locus-tag	class	description
KBP49_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KBP49_00020	COG0187	DNA topoisomerase II activity
KBP49_00030	COG0501	Belongs to the peptidase M48B family
KBP49_00085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KBP49_00145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KBP49_00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KBP49_00165	COG0511	ligase activity, forming carbon-carbon bonds
KBP49_00170	COG0439	Biotin carboxylase
KBP49_00175	COG0210	DNA helicase
KBP49_00200	COG1040	competence protein
KBP49_00210	COG1752	Esterase of the alpha-beta hydrolase superfamily
KBP49_00250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KBP49_00260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KBP49_00285	COG3121	Chaperone
KBP49_00290	COG3539	Fimbrial protein
KBP49_00295	COG1546	Belongs to the CinA family
KBP49_00300	COG0477	Major facilitator Superfamily
KBP49_00305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KBP49_00320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KBP49_00325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KBP49_00335	COG1534	Rna-binding protein
KBP49_00365	COG1560	Kdo2-lipid A biosynthetic process
KBP49_00370	COG1519	Transferase
KBP49_00390	COG0336	Belongs to the RNA methyltransferase TrmD family
KBP49_00410	COG1393	Belongs to the ArsC family
KBP49_00420	COG0367	asparagine synthase
KBP49_00430	COG2070	2-Nitropropane dioxygenase
KBP49_00460	COG0339	signal peptide processing
KBP49_00540	COG4221	oxidoreductase activity
KBP49_00560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KBP49_00570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBP49_00615	COG2223	nitrite transmembrane transporter activity
KBP49_00625	COG0739	heme binding
KBP49_00660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KBP49_00675	COG1028	Short-chain dehydrogenase reductase Sdr
KBP49_00685	COG1272	protein, Hemolysin III
KBP49_00690	COG0463	Glycosyl transferase, family 2
KBP49_00695	COG0084	hydrolase, TatD family'
KBP49_00725	COG0330	HflC and HflK could
KBP49_00730	COG3956	TIGRFAM MazG family protein
KBP49_00740	COG0494	nUDIX hydrolase
KBP49_00750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KBP49_00755	COG0513	Belongs to the DEAD box helicase family
KBP49_00760	COG0720	synthase
KBP49_00785	COG1981	membrane
KBP49_00820	COG0512	Glutamine amidotransferase of anthranilate synthase
KBP49_00850	COG0006	proline dipeptidase activity
KBP49_00870	COG1862	Preprotein translocase
KBP49_00875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBP49_00880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBP49_00890	COG0617	tRNA 3'-terminal CCA addition
KBP49_00930	COG0195	Participates in both transcription termination and antitermination
KBP49_00960	COG1733	regulation of RNA biosynthetic process
KBP49_00965	COG0702	epimerase
KBP49_01015	COG2086	electron transfer activity
KBP49_01045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBP49_01075	COG0477	Major facilitator Superfamily
KBP49_01095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KBP49_01100	COG0671	phosphoesterase, PA-phosphatase related
KBP49_01115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KBP49_01120	COG0628	permease
KBP49_01140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBP49_01145	COG1090	epimerase
KBP49_01150	COG0318	PFAM AMP-dependent synthetase and ligase
KBP49_01170	COG1049	propionate catabolic process, 2-methylcitrate cycle
KBP49_01190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP49_01195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP49_01225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBP49_01250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KBP49_01270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KBP49_01275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KBP49_01280	COG1034	ATP synthesis coupled electron transport
KBP49_01315	COG1007	ATP synthesis coupled electron transport
KBP49_01320	COG1028	Short-chain dehydrogenase reductase Sdr
KBP49_01325	COG2851	Citrate transporter
KBP49_01340	COG0642	Histidine kinase
KBP49_01355	COG0784	Response regulator, receiver
KBP49_01355	COG2205	protein histidine kinase activity
KBP49_01375	COG0280	phosphate acetyltransferase
KBP49_01375	COG0281	malic enzyme
KBP49_01385	COG0742	ribosomal rna small subunit methyltransferase
KBP49_01400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KBP49_01420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KBP49_01445	COG2166	iron-sulfur cluster assembly
KBP49_01470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KBP49_01535	COG1321	iron dependent repressor
KBP49_01555	COG1946	Acyl-CoA thioesterase
KBP49_01640	COG0750	zinc metalloprotease
KBP49_01650	COG0575	Belongs to the CDS family
KBP49_01655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KBP49_01690	COG0528	UMP kinase activity
KBP49_01735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KBP49_01745	COG0354	folic acid binding
KBP49_01755	COG2009	succinate dehydrogenase
KBP49_01760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KBP49_01770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KBP49_01800	COG0811	peptide transport
KBP49_01955	COG3772	lysozyme
KBP49_02030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBP49_02100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KBP49_02125	COG1024	Enoyl-CoA hydratase
KBP49_02130	COG0527	aspartate kinase activity
KBP49_02150	COG0494	nUDIX hydrolase
KBP49_02155	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KBP49_02165	COG0424	maF-like protein
KBP49_02180	COG0312	modulator of DNA gyrase
KBP49_02190	COG0312	modulator of DNA gyrase
KBP49_02195	COG0583	DNA-binding transcription factor activity
KBP49_02210	COG1064	alcohol dehydrogenase
KBP49_02265	COG0356	it plays a direct role in the translocation of protons across the membrane
KBP49_02320	COG0255	Belongs to the universal ribosomal protein uL29 family
KBP49_02380	COG0201	protein transport
KBP49_02410	COG2960	long-chain fatty acid transporting porin activity
KBP49_02415	COG0606	chelatase, subunit chli
KBP49_02435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KBP49_02495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBP49_02500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBP49_02515	COG1187	pseudouridine synthase activity
KBP49_02540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBP49_02545	COG0625	glutathione transferase activity
KBP49_02555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KBP49_02560	COG1217	gtp-binding protein TYPA
KBP49_02600	COG0842	Transport permease protein
KBP49_02605	COG1131	(ABC) transporter
KBP49_02625	COG1643	Atp-dependent helicase
KBP49_02640	COG1956	GAF domain-containing protein
KBP49_02650	COG0729	surface antigen
KBP49_02655	COG2911	Protein conserved in bacteria
KBP49_02665	COG0582	viral genome integration into host DNA
KBP49_02735	COG2337	Toxic component of a toxin-antitoxin (TA) module
KBP49_02740	COG0582	viral genome integration into host DNA
KBP49_02880	COG0668	transmembrane transport
KBP49_02910	COG5297	Belongs to the glycosyl hydrolase family 6
KBP49_02915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KBP49_02950	COG2733	membrane
KBP49_02955	COG1253	flavin adenine dinucleotide binding
KBP49_02985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KBP49_03005	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KBP49_03020	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KBP49_03020	COG0644	oxidoreductase
KBP49_03035	COG3218	ABC-type transport auxiliary lipoprotein component
KBP49_03035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KBP49_03040	COG1127	ABC transporter
KBP49_03045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBP49_03080	COG0629	single-stranded DNA binding
KBP49_03100	COG4969	Belongs to the N-Me-Phe pilin family
KBP49_03235	COG1077	Cell shape determining protein MreB Mrl
KBP49_03240	COG1792	Involved in formation and maintenance of cell shape
KBP49_03245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KBP49_03250	COG0768	penicillin binding
KBP49_03255	COG0772	Belongs to the SEDS family
KBP49_03265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBP49_03285	COG2894	cell division
KBP49_03305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KBP49_03320	COG2353	YceI-like domain
KBP49_03325	COG2205	protein histidine kinase activity
KBP49_03325	COG2198	Histidine kinase
KBP49_03325	COG0784	Response regulator, receiver
KBP49_03370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KBP49_03375	COG4208	sulfate ABC transporter
KBP49_03400	COG1846	Transcriptional regulator
KBP49_03430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KBP49_03440	COG0741	lytic transglycosylase activity
KBP49_03470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KBP49_03505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBP49_03515	COG0514	ATP-dependent DNA helicase (RecQ)
KBP49_03520	COG0783	Belongs to the Dps family
KBP49_03525	COG1643	Atp-dependent helicase
KBP49_03540	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KBP49_03545	COG1845	cytochrome c oxidase, subunit III
KBP49_03550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBP49_03555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KBP49_03560	COG0142	geranyltranstransferase activity
KBP49_03565	COG0629	single-stranded DNA binding
KBP49_03590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KBP49_03625	COG1137	ATPase activity
KBP49_03640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KBP49_03650	COG0271	Belongs to the BolA IbaG family
KBP49_03685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBP49_03695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KBP49_03710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KBP49_03730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBP49_03760	COG0542	response to heat
KBP49_03780	COG0492	ferredoxin-NADP+ reductase activity
KBP49_03800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KBP49_03810	COG4191	Histidine kinase
KBP49_03815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KBP49_03820	COG1028	Short-chain dehydrogenase reductase Sdr
KBP49_03850	COG1609	Transcriptional regulator
KBP49_03855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KBP49_03860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KBP49_03865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KBP49_03870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBP49_03875	COG0726	polysaccharide deacetylase
KBP49_03880	COG0297	glycogen (starch) synthase activity
KBP49_03895	COG0719	Fe-S assembly protein
KBP49_03900	COG0396	ATPase activity
KBP49_03905	COG0719	Fe-S assembly protein
KBP49_03910	COG1959	2 iron, 2 sulfur cluster binding
KBP49_03965	COG0308	aminopeptidase N
KBP49_04010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KBP49_04035	COG1561	YicC-like family, N-terminal region
KBP49_04050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KBP49_04085	COG5295	Hep Hag repeat protein
KBP49_04090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KBP49_04095	COG1459	type II secretion system
KBP49_04100	COG2165	general secretion pathway protein
KBP49_04105	COG4970	Tfp pilus assembly protein FimT
KBP49_04110	COG2165	general secretion pathway protein
KBP49_04115	COG4795	General secretion pathway protein
KBP49_04120	COG3156	type II secretion system protein K
KBP49_04125	COG3166	PFAM Fimbrial assembly family protein
KBP49_04140	COG1450	Type ii and iii secretion system protein
KBP49_04160	COG3634	alkyl hydroperoxide reductase activity
KBP49_04165	COG0583	DNA-binding transcription factor activity
KBP49_04230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KBP49_04250	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBP49_04255	COG0567	Dehydrogenase, E1 component
KBP49_04260	COG2850	peptidyl-arginine hydroxylation
KBP49_04365	COG3772	lysozyme
KBP49_04530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBP49_04535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBP49_04540	COG2902	Dehydrogenase
KBP49_04580	COG1028	Short-chain dehydrogenase reductase Sdr
KBP49_04590	COG1472	Belongs to the glycosyl hydrolase 3 family
KBP49_04630	COG2925	Exonuclease
KBP49_04640	COG0025	NhaP-type Na H and K H
KBP49_04660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KBP49_04685	COG0006	proline dipeptidase activity
KBP49_04695	COG0778	Nitroreductase
KBP49_04725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KBP49_04765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBP49_04775	COG0557	exoribonuclease II activity
KBP49_04785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KBP49_04800	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KBP49_04805	COG1289	transmembrane transporter activity
KBP49_04820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KBP49_04830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBP49_04845	COG0596	Alpha beta hydrolase
KBP49_04850	COG0727	PFAM Uncharacterised protein family (UPF0153)
KBP49_04855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KBP49_04855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KBP49_04895	COG0840	transmembrane signaling receptor activity
KBP49_04900	COG0784	Response regulator, receiver
KBP49_04900	COG2198	Histidine kinase
KBP49_04900	COG0643	Histidine kinase
KBP49_04930	COG0285	dihydrofolate synthase activity
KBP49_04940	COG0339	signal peptide processing
KBP49_04960	COG1301	dicarboxylic acid transport
KBP49_04965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KBP49_04975	COG2091	lysine biosynthetic process via aminoadipic acid
KBP49_05010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KBP49_05035	COG0084	hydrolase, TatD family'
KBP49_05050	COG0552	protein localization to endoplasmic reticulum
KBP49_05095	COG0824	Thioesterase
KBP49_05120	COG2885	chlorophyll binding
KBP49_05130	COG0602	queuosine metabolic process
KBP49_05150	COG0386	Belongs to the glutathione peroxidase family
KBP49_05170	COG0406	alpha-ribazole phosphatase activity
KBP49_05295	COG3852	Histidine kinase
KBP49_05300	COG2204	response regulator
KBP49_05315	COG0004	ammonium transporteR
KBP49_05320	COG0347	Belongs to the P(II) protein family
KBP49_05325	COG0174	glutamine synthetase
KBP49_05330	COG1968	undecaprenyl-diphosphatase activity
KBP49_05335	COG2353	YceI-like domain
KBP49_05390	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KBP49_05395	COG1764	response to oxidative stress
KBP49_05400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBP49_05445	COG1399	metal-binding, possibly nucleic acid-binding protein
KBP49_05455	COG0714	Associated with various cellular activities
KBP49_05475	COG0537	adenosine 5'-monophosphoramidase activity
KBP49_05525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KBP49_05555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KBP49_05575	COG4969	Belongs to the N-Me-Phe pilin family
KBP49_05590	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KBP49_05595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KBP49_05605	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KBP49_05620	COG0251	oxidation-reduction process
KBP49_05625	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KBP49_05625	COG0392	lysyltransferase activity
KBP49_05635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KBP49_05645	COG0463	Glycosyl transferase, family 2
KBP49_05690	COG3275	phosphorelay sensor kinase activity
KBP49_05695	COG0400	carboxylic ester hydrolase activity
KBP49_05715	COG2226	methyltransferase
KBP49_05730	COG2027	D-alanyl-D-alanine carboxypeptidase
KBP49_05745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBP49_05775	COG0386	Belongs to the glutathione peroxidase family
KBP49_05780	COG1131	(ABC) transporter
KBP49_05810	COG3657	addiction module killer protein
KBP49_05815	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KBP49_05880	COG2369	cell adhesion
KBP49_05895	COG3567	Phage-associated protein, HI1409 family
KBP49_05900	COG5410	chromosome segregation
KBP49_05925	COG3772	lysozyme
KBP49_05995	COG0489	protein tyrosine kinase activity
KBP49_06005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KBP49_06070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KBP49_06075	COG0488	(ABC) transporter
KBP49_06095	COG4651	solute:proton antiporter activity
KBP49_06095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KBP49_06155	COG0859	PFAM glycosyl transferase family 9
KBP49_06170	COG0631	protein serine/threonine phosphatase activity
KBP49_06175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KBP49_06180	COG0328	RNA-DNA hybrid ribonuclease activity
KBP49_06205	COG2183	response to ionizing radiation
KBP49_06220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KBP49_06225	COG3118	belongs to the thioredoxin family
KBP49_06275	COG2951	lytic endotransglycosylase activity
KBP49_06280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KBP49_06445	COG0277	FAD linked oxidase domain protein
KBP49_06450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KBP49_06455	COG0531	amino acid
KBP49_06470	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KBP49_06545	COG0527	aspartate kinase activity
KBP49_06545	COG0460	homoserine dehydrogenase
KBP49_06550	COG0540	Belongs to the ATCase OTCase family
KBP49_06565	COG1686	Belongs to the peptidase S11 family
KBP49_06590	COG4953	penicillin-binding protein 1C
KBP49_06620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBP49_06690	COG1506	peptidase
KBP49_06690	COG0823	Involved in the tonB-independent uptake of proteins
KBP49_06695	COG1297	OPT oligopeptide transporter protein
KBP49_06725	COG0676	glucose-6-phosphate 1-epimerase activity
KBP49_06735	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KBP49_06740	COG1335	isochorismatase
KBP49_06745	COG0318	PFAM AMP-dependent synthetase and ligase
KBP49_06755	COG0463	Glycosyl transferase, family 2
KBP49_06770	COG1192	Involved in chromosome partitioning
KBP49_06830	COG3772	lysozyme
KBP49_06880	COG1605	Chorismate mutase
KBP49_06880	COG0077	Prephenate dehydratase
KBP49_06895	COG1668	transmembrane transport
KBP49_06900	COG4555	ABC transporter
KBP49_06925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KBP49_06940	COG0287	Prephenate dehydrogenase
KBP49_06940	COG1605	Chorismate mutase
KBP49_06965	COG0497	DNA recombination
KBP49_06975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBP49_06980	COG2914	Belongs to the UPF0125 (RnfH) family
KBP49_07000	COG1278	Cold shock
KBP49_07010	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KBP49_07020	COG2954	triphosphatase activity
KBP49_07030	COG0745	RESPONSE REGULATOR receiver
KBP49_07035	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KBP49_07040	COG0438	transferase activity, transferring glycosyl groups
KBP49_07050	COG0438	transferase activity, transferring glycosyl groups
KBP49_07110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBP49_07115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBP49_07140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBP49_07180	COG3609	addiction module antidote protein, CC2985 family
KBP49_07190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KBP49_07195	COG0675	Transposase, IS605 OrfB family
KBP49_07205	COG0436	Aminotransferase
KBP49_07270	COG0196	riboflavin kinase activity
KBP49_07275	COG0728	peptidoglycan biosynthetic process
KBP49_07280	COG0268	Binds directly to 16S ribosomal RNA
KBP49_07300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KBP49_07320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KBP49_07325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KBP49_07340	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KBP49_07350	COG0776	regulation of translation
KBP49_07395	COG0395	ABC-type sugar transport system, permease component
KBP49_07400	COG1175	transmembrane transport
KBP49_07425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KBP49_07445	COG0436	Aminotransferase
KBP49_07470	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KBP49_07480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBP49_07510	COG5434	Belongs to the glycosyl hydrolase 28 family
KBP49_07535	COG0402	S-adenosylhomocysteine deaminase activity
KBP49_07545	COG1509	lysine 2,3-aminomutase activity
KBP49_07580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KBP49_07585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KBP49_07600	COG1028	Short-chain dehydrogenase reductase Sdr
KBP49_07675	COG0142	geranyltranstransferase activity
KBP49_07685	COG0037	tRNA processing
KBP49_07695	COG1301	dicarboxylic acid transport
KBP49_07705	COG0791	NLP P60 protein
KBP49_07710	COG0791	NLP P60 protein
KBP49_07720	COG2311	Membrane
KBP49_07735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KBP49_07855	COG0351	phosphomethylpyrimidine kinase
KBP49_07855	COG0352	thiamine-phosphate diphosphorylase activity
KBP49_07865	COG1324	tolerance protein
KBP49_07900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBP49_07905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBP49_07910	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KBP49_07925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KBP49_07945	COG4774	siderophore transport
KBP49_07970	COG1477	protein flavinylation
KBP49_07975	COG1555	photosystem II stabilization
KBP49_07980	COG3178	'Phosphotransferase
KBP49_07985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KBP49_07995	COG0628	permease
KBP49_08010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KBP49_08035	COG3590	peptidase
KBP49_08095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KBP49_08095	COG0519	Catalyzes the synthesis of GMP from XMP
KBP49_08110	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KBP49_08125	COG3107	peptidoglycan biosynthetic process
KBP49_08145	COG2878	Part of a membrane complex involved in electron transport
KBP49_08250	COG1611	Belongs to the LOG family
KBP49_08255	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KBP49_08260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KBP49_08270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBP49_08300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KBP49_08315	COG0330	HflC and HflK could
KBP49_08320	COG0330	HflC and HflK could
KBP49_08325	COG0604	alcohol dehydrogenase
KBP49_08355	COG1183	phosphatidylcholine synthase activity
KBP49_08375	COG0668	transmembrane transport
KBP49_08380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KBP49_08395	COG1610	YqeY-like protein
KBP49_08405	COG0358	DNA primase activity
KBP49_08440	COG1074	ATP-dependent DNA helicase activity
KBP49_08445	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KBP49_08450	COG1127	ABC transporter
KBP49_08455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBP49_08475	COG2853	Lipoprotein
KBP49_08480	COG1322	Protein conserved in bacteria
KBP49_08485	COG1116	anion transmembrane transporter activity
KBP49_08495	COG0531	amino acid
KBP49_08500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KBP49_08505	COG0861	Integral membrane protein TerC family
KBP49_08550	COG2193	ferroxidase activity
KBP49_08630	COG2124	cytochrome p450
KBP49_08635	COG2194	sulfuric ester hydrolase activity
KBP49_08675	COG0667	Aldo Keto reductase
KBP49_08680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBP49_08690	COG0305	Participates in initiation and elongation during chromosome replication
KBP49_08710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KBP49_08720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBP49_08725	COG0277	FAD linked oxidase domain protein
KBP49_08735	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KBP49_08740	COG4206	TonB-dependent receptor
KBP49_08770	COG0675	Transposase, IS605 OrfB family
KBP49_08820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KBP49_08840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KBP49_08870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBP49_08870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBP49_08890	COG0488	(ABC) transporter
KBP49_08900	COG3011	Protein conserved in bacteria
KBP49_08915	COG0564	pseudouridine synthase activity
KBP49_08930	COG1918	ferrous iron import across plasma membrane
KBP49_08930	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KBP49_08940	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KBP49_08965	COG0758	DNA mediated transformation
KBP49_09010	COG2969	positive regulation of protein catabolic process
KBP49_09015	COG0625	glutathione transferase activity
KBP49_09020	COG2857	Cytochrome c1
KBP49_09025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KBP49_09030	COG0723	plastoquinol--plastocyanin reductase activity
KBP49_09035	COG0741	lytic transglycosylase activity
KBP49_09045	COG1702	phosphate starvation-inducible protein PhoH
KBP49_09060	COG4535	Mg2 and Co2 transporter CorC
KBP49_09070	COG0598	Magnesium transport protein CorA
KBP49_09145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KBP49_09155	COG1199	ATP-dependent helicase activity
KBP49_09165	COG0288	reversible hydration of carbon dioxide
KBP49_09190	COG2011	ABC-type metal ion transport system permease component
KBP49_09195	COG1464	Belongs to the NlpA lipoprotein family
KBP49_09210	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBP49_09215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KBP49_09230	COG0626	cystathionine gamma-synthase activity
KBP49_09235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBP49_09240	COG0739	heme binding
KBP49_09255	COG1238	metal cluster binding
KBP49_09275	COG5002	protein histidine kinase activity
KBP49_09295	COG1388	LysM domain
KBP49_09295	COG3858	chitin binding
KBP49_09300	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KBP49_09310	COG1472	Belongs to the glycosyl hydrolase 3 family
KBP49_09325	COG3537	Alpha-1,2-mannosidase
KBP49_09350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBP49_09355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBP49_09400	COG0469	pyruvate kinase activity
KBP49_09420	COG0735	belongs to the Fur family
KBP49_09430	COG5297	Belongs to the glycosyl hydrolase family 6
KBP49_09430	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBP49_09440	COG0612	Peptidase, M16
KBP49_09455	COG4305	rare lipoprotein A
KBP49_09465	COG0739	heme binding
KBP49_09475	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KBP49_09490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KBP49_09520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KBP49_09535	COG3116	cell division
KBP49_09550	COG0471	metal ion transport
KBP49_09550	COG3273	potassium ion transport
KBP49_09605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KBP49_09670	COG0860	N-Acetylmuramoyl-L-alanine amidase
KBP49_09675	COG0802	atpase or kinase
KBP49_09680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KBP49_09680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KBP49_09685	COG1570	exodeoxyribonuclease VII activity
KBP49_09750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KBP49_09770	COG0745	RESPONSE REGULATOR receiver
KBP49_09775	COG0642	Histidine kinase
KBP49_09785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KBP49_09830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KBP49_09840	COG2831	hemolysin activation secretion protein
KBP49_09865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KBP49_09905	COG0316	Belongs to the HesB IscA family
KBP49_09940	COG0697	spore germination
KBP49_09945	COG0671	phosphoesterase, PA-phosphatase related
KBP49_09950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KBP49_09960	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KBP49_09965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KBP49_09980	COG1132	(ABC) transporter
KBP49_09985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KBP49_09990	COG1538	Outer membrane efflux protein
KBP49_10020	COG0745	RESPONSE REGULATOR receiver
KBP49_10025	COG4783	chaperone-mediated protein folding
KBP49_10035	COG0473	3-isopropylmalate dehydrogenase activity
KBP49_10045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KBP49_10050	COG3083	sulfuric ester hydrolase activity
KBP49_10055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KBP49_10080	COG0564	pseudouridine synthase activity
KBP49_10085	COG1530	ribonuclease E activity
KBP49_10090	COG2197	response regulator
KBP49_10105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KBP49_10120	COG0488	(ABC) transporter
KBP49_10135	COG1278	Cold shock
KBP49_10140	COG2203	Gaf domain
KBP49_10140	COG3706	GGDEF domain
KBP49_10140	COG4251	negative regulation of phosphorylation
KBP49_10140	COG5001	Diguanylate cyclase
KBP49_10150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBP49_10180	COG0222	ribosome binding
KBP49_10195	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KBP49_10200	COG0250	Participates in transcription elongation, termination and antitermination
KBP49_10205	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KBP49_10215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBP49_10235	COG0012	GTP binding
KBP49_10250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KBP49_10330	COG2095	MarC family integral membrane protein
KBP49_10340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBP49_10370	COG2132	Multicopper oxidase
KBP49_10380	COG0210	DNA helicase
KBP49_10390	COG0616	signal peptide processing
KBP49_10410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KBP49_10425	COG2201	protein-glutamate methylesterase activity
KBP49_10430	COG2177	Part of the ABC transporter FtsEX involved in
KBP49_10435	COG2884	Cell division ATP-binding protein ftsE
KBP49_10440	COG0513	Belongs to the DEAD box helicase family
KBP49_10445	COG3118	belongs to the thioredoxin family
KBP49_10450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KBP49_10465	COG0793	Belongs to the peptidase S41A family
KBP49_10470	COG4942	peptidase
KBP49_10485	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBP49_10490	COG0493	'glutamate synthase
KBP49_10495	COG0070	glutamate synthase
KBP49_10495	COG0069	glutamate synthase activity
KBP49_10495	COG0067	glutamate synthase
KBP49_10545	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP49_10590	COG1280	lysine exporter protein (LysE YggA)
KBP49_10605	COG4942	peptidase
KBP49_10640	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP49_10655	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KBP49_10755	COG1487	ribonuclease activity
KBP49_10760	COG4691	Plasmid stability protein
KBP49_10845	COG0594	ribonuclease P activity