locus-tag	class	description
KBP48_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KBP48_00020	COG0187	DNA topoisomerase II activity
KBP48_00030	COG0501	Belongs to the peptidase M48B family
KBP48_00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KBP48_00145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KBP48_00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KBP48_00165	COG0511	ligase activity, forming carbon-carbon bonds
KBP48_00170	COG0439	Biotin carboxylase
KBP48_00175	COG0210	DNA helicase
KBP48_00205	COG1752	Esterase of the alpha-beta hydrolase superfamily
KBP48_00255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KBP48_00280	COG3121	Chaperone
KBP48_00285	COG3539	Fimbrial protein
KBP48_00290	COG1546	Belongs to the CinA family
KBP48_00295	COG0477	Major facilitator Superfamily
KBP48_00300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KBP48_00315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KBP48_00320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KBP48_00330	COG1534	Rna-binding protein
KBP48_00360	COG1560	Kdo2-lipid A biosynthetic process
KBP48_00365	COG1519	Transferase
KBP48_00385	COG0336	Belongs to the RNA methyltransferase TrmD family
KBP48_00405	COG1393	Belongs to the ArsC family
KBP48_00415	COG0367	asparagine synthase
KBP48_00425	COG2070	2-Nitropropane dioxygenase
KBP48_00455	COG0339	signal peptide processing
KBP48_00535	COG4221	oxidoreductase activity
KBP48_00555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KBP48_00565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBP48_00610	COG2223	nitrite transmembrane transporter activity
KBP48_00670	COG1028	Short-chain dehydrogenase reductase Sdr
KBP48_00680	COG1272	protein, Hemolysin III
KBP48_00685	COG0463	Glycosyl transferase, family 2
KBP48_00690	COG0084	hydrolase, TatD family'
KBP48_00720	COG0330	HflC and HflK could
KBP48_00725	COG3956	TIGRFAM MazG family protein
KBP48_00735	COG0494	nUDIX hydrolase
KBP48_00745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KBP48_00750	COG0513	Belongs to the DEAD box helicase family
KBP48_00755	COG0720	synthase
KBP48_00780	COG1981	membrane
KBP48_00815	COG0512	Glutamine amidotransferase of anthranilate synthase
KBP48_00845	COG0006	proline dipeptidase activity
KBP48_00865	COG1862	Preprotein translocase
KBP48_00870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBP48_00875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KBP48_00885	COG0617	tRNA 3'-terminal CCA addition
KBP48_00925	COG0195	Participates in both transcription termination and antitermination
KBP48_00955	COG1733	regulation of RNA biosynthetic process
KBP48_00960	COG0702	epimerase
KBP48_01010	COG2086	electron transfer activity
KBP48_01040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBP48_01065	COG0477	Major facilitator Superfamily
KBP48_01085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KBP48_01090	COG0671	phosphoesterase, PA-phosphatase related
KBP48_01105	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KBP48_01110	COG0628	permease
KBP48_01130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBP48_01135	COG1090	epimerase
KBP48_01140	COG0318	PFAM AMP-dependent synthetase and ligase
KBP48_01160	COG1049	propionate catabolic process, 2-methylcitrate cycle
KBP48_01180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP48_01185	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP48_01225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBP48_01250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KBP48_01270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KBP48_01275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KBP48_01280	COG1034	ATP synthesis coupled electron transport
KBP48_01315	COG1007	ATP synthesis coupled electron transport
KBP48_01320	COG1028	Short-chain dehydrogenase reductase Sdr
KBP48_01325	COG2851	Citrate transporter
KBP48_01340	COG0642	Histidine kinase
KBP48_01355	COG0784	Response regulator, receiver
KBP48_01355	COG2205	protein histidine kinase activity
KBP48_01375	COG0280	phosphate acetyltransferase
KBP48_01375	COG0281	malic enzyme
KBP48_01385	COG0742	ribosomal rna small subunit methyltransferase
KBP48_01405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KBP48_01425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KBP48_01450	COG2166	iron-sulfur cluster assembly
KBP48_01480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KBP48_01565	COG1321	iron dependent repressor
KBP48_01570	COG1914	H( )-stimulated, divalent metal cation uptake system
KBP48_01585	COG1946	Acyl-CoA thioesterase
KBP48_01665	COG0750	zinc metalloprotease
KBP48_01675	COG0575	Belongs to the CDS family
KBP48_01680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KBP48_01710	COG0528	UMP kinase activity
KBP48_01755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KBP48_01765	COG0354	folic acid binding
KBP48_01775	COG2009	succinate dehydrogenase
KBP48_01780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KBP48_01790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KBP48_01820	COG0811	peptide transport
KBP48_01975	COG3772	lysozyme
KBP48_02050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBP48_02125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KBP48_02150	COG1024	Enoyl-CoA hydratase
KBP48_02155	COG0527	aspartate kinase activity
KBP48_02175	COG0494	nUDIX hydrolase
KBP48_02180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KBP48_02190	COG0424	maF-like protein
KBP48_02205	COG0312	modulator of DNA gyrase
KBP48_02215	COG0312	modulator of DNA gyrase
KBP48_02220	COG0583	DNA-binding transcription factor activity
KBP48_02235	COG1064	alcohol dehydrogenase
KBP48_02290	COG0356	it plays a direct role in the translocation of protons across the membrane
KBP48_02345	COG0255	Belongs to the universal ribosomal protein uL29 family
KBP48_02405	COG0201	protein transport
KBP48_02435	COG2960	long-chain fatty acid transporting porin activity
KBP48_02440	COG0606	chelatase, subunit chli
KBP48_02460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KBP48_02520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBP48_02525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KBP48_02540	COG1187	pseudouridine synthase activity
KBP48_02565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KBP48_02570	COG0625	glutathione transferase activity
KBP48_02580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KBP48_02585	COG1217	gtp-binding protein TYPA
KBP48_02625	COG0842	Transport permease protein
KBP48_02630	COG1131	(ABC) transporter
KBP48_02650	COG1643	Atp-dependent helicase
KBP48_02665	COG1956	GAF domain-containing protein
KBP48_02675	COG0729	surface antigen
KBP48_02680	COG2911	Protein conserved in bacteria
KBP48_02690	COG0582	viral genome integration into host DNA
KBP48_02835	COG0668	transmembrane transport
KBP48_02865	COG5297	Belongs to the glycosyl hydrolase family 6
KBP48_02870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KBP48_02905	COG2733	membrane
KBP48_02910	COG1253	flavin adenine dinucleotide binding
KBP48_02940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KBP48_02960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KBP48_02975	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KBP48_02975	COG0644	oxidoreductase
KBP48_02990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KBP48_02990	COG3218	ABC-type transport auxiliary lipoprotein component
KBP48_02995	COG1127	ABC transporter
KBP48_03000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBP48_03030	COG0827	DNA restriction-modification system
KBP48_03035	COG0827	DNA restriction-modification system
KBP48_03060	COG0629	single-stranded DNA binding
KBP48_03080	COG4969	Belongs to the N-Me-Phe pilin family
KBP48_03225	COG0675	Transposase, IS605 OrfB family
KBP48_03230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KBP48_03240	COG3609	addiction module antidote protein, CC2985 family
KBP48_03295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBP48_03315	COG1064	alcohol dehydrogenase
KBP48_03330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBP48_03335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBP48_03395	COG0438	transferase activity, transferring glycosyl groups
KBP48_03405	COG0438	transferase activity, transferring glycosyl groups
KBP48_03410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KBP48_03415	COG0745	RESPONSE REGULATOR receiver
KBP48_03425	COG2954	triphosphatase activity
KBP48_03435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KBP48_03445	COG1278	Cold shock
KBP48_03465	COG2914	Belongs to the UPF0125 (RnfH) family
KBP48_03470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBP48_03505	COG0287	Prephenate dehydrogenase
KBP48_03505	COG1605	Chorismate mutase
KBP48_03520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KBP48_03545	COG4555	ABC transporter
KBP48_03550	COG1668	transmembrane transport
KBP48_03565	COG0077	Prephenate dehydratase
KBP48_03565	COG1605	Chorismate mutase
KBP48_03615	COG3772	lysozyme
KBP48_03675	COG1192	Involved in chromosome partitioning
KBP48_03690	COG0463	Glycosyl transferase, family 2
KBP48_03700	COG0318	PFAM AMP-dependent synthetase and ligase
KBP48_03705	COG1335	isochorismatase
KBP48_03710	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KBP48_03720	COG0676	glucose-6-phosphate 1-epimerase activity
KBP48_03750	COG1297	OPT oligopeptide transporter protein
KBP48_03755	COG1506	peptidase
KBP48_03755	COG0823	Involved in the tonB-independent uptake of proteins
KBP48_03825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KBP48_03850	COG4953	penicillin-binding protein 1C
KBP48_03875	COG1686	Belongs to the peptidase S11 family
KBP48_03890	COG0540	Belongs to the ATCase OTCase family
KBP48_03895	COG0527	aspartate kinase activity
KBP48_03895	COG0460	homoserine dehydrogenase
KBP48_03970	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KBP48_03980	COG0531	amino acid
KBP48_03985	COG0531	amino acid
KBP48_03990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KBP48_03995	COG0277	FAD linked oxidase domain protein
KBP48_04035	COG3210	domain, Protein
KBP48_04275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KBP48_04280	COG2951	lytic endotransglycosylase activity
KBP48_04330	COG3118	belongs to the thioredoxin family
KBP48_04335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KBP48_04350	COG2183	response to ionizing radiation
KBP48_04375	COG0328	RNA-DNA hybrid ribonuclease activity
KBP48_04380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KBP48_04385	COG0631	protein serine/threonine phosphatase activity
KBP48_04400	COG0859	PFAM glycosyl transferase family 9
KBP48_04460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KBP48_04460	COG4651	solute:proton antiporter activity
KBP48_04480	COG0488	(ABC) transporter
KBP48_04545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KBP48_04555	COG0489	protein tyrosine kinase activity
KBP48_04625	COG3772	lysozyme
KBP48_04650	COG5410	chromosome segregation
KBP48_04655	COG3567	Phage-associated protein, HI1409 family
KBP48_04670	COG2369	cell adhesion
KBP48_04740	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KBP48_04745	COG3657	addiction module killer protein
KBP48_04775	COG1131	(ABC) transporter
KBP48_04780	COG0386	Belongs to the glutathione peroxidase family
KBP48_04810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBP48_04825	COG2027	D-alanyl-D-alanine carboxypeptidase
KBP48_04840	COG2226	methyltransferase
KBP48_04860	COG0400	carboxylic ester hydrolase activity
KBP48_04865	COG3275	phosphorelay sensor kinase activity
KBP48_04910	COG0463	Glycosyl transferase, family 2
KBP48_04920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KBP48_04930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KBP48_04930	COG0392	lysyltransferase activity
KBP48_04935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KBP48_04970	COG3617	BRO family, N-terminal domain
KBP48_05065	COG3772	lysozyme
KBP48_05165	COG0251	oxidation-reduction process
KBP48_05180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KBP48_05190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KBP48_05195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KBP48_05230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KBP48_05260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KBP48_05315	COG0537	adenosine 5'-monophosphoramidase activity
KBP48_05335	COG0714	Associated with various cellular activities
KBP48_05345	COG1399	metal-binding, possibly nucleic acid-binding protein
KBP48_05390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBP48_05395	COG1764	response to oxidative stress
KBP48_05400	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KBP48_05455	COG2353	YceI-like domain
KBP48_05460	COG1968	undecaprenyl-diphosphatase activity
KBP48_05465	COG0174	glutamine synthetase
KBP48_05470	COG0347	Belongs to the P(II) protein family
KBP48_05475	COG0004	ammonium transporteR
KBP48_05490	COG2204	response regulator
KBP48_05495	COG3852	Histidine kinase
KBP48_05610	COG0582	viral genome integration into host DNA
KBP48_05615	COG2337	Toxic component of a toxin-antitoxin (TA) module
KBP48_05705	COG0406	alpha-ribazole phosphatase activity
KBP48_05725	COG0386	Belongs to the glutathione peroxidase family
KBP48_05745	COG0602	queuosine metabolic process
KBP48_05755	COG2885	chlorophyll binding
KBP48_05780	COG0824	Thioesterase
KBP48_05825	COG0552	protein localization to endoplasmic reticulum
KBP48_05840	COG0084	hydrolase, TatD family'
KBP48_05865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KBP48_05900	COG2091	lysine biosynthetic process via aminoadipic acid
KBP48_05910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KBP48_05915	COG1301	dicarboxylic acid transport
KBP48_05935	COG0339	signal peptide processing
KBP48_05945	COG0285	dihydrofolate synthase activity
KBP48_05975	COG2198	Histidine kinase
KBP48_05975	COG0643	Histidine kinase
KBP48_05975	COG0784	Response regulator, receiver
KBP48_05980	COG0840	transmembrane signaling receptor activity
KBP48_06025	COG0727	PFAM Uncharacterised protein family (UPF0153)
KBP48_06030	COG0596	Alpha beta hydrolase
KBP48_06045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KBP48_06055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KBP48_06070	COG1289	transmembrane transporter activity
KBP48_06075	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KBP48_06090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KBP48_06100	COG0557	exoribonuclease II activity
KBP48_06110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBP48_06150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KBP48_06185	COG0778	Nitroreductase
KBP48_06195	COG0006	proline dipeptidase activity
KBP48_06220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KBP48_06240	COG0025	NhaP-type Na H and K H
KBP48_06250	COG2925	Exonuclease
KBP48_06290	COG1472	Belongs to the glycosyl hydrolase 3 family
KBP48_06300	COG1028	Short-chain dehydrogenase reductase Sdr
KBP48_06340	COG2902	Dehydrogenase
KBP48_06345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KBP48_06350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KBP48_06430	COG3772	lysozyme
KBP48_06435	COG0675	Transposase, IS605 OrfB family
KBP48_06485	COG2850	peptidyl-arginine hydroxylation
KBP48_06490	COG0567	Dehydrogenase, E1 component
KBP48_06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBP48_06515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KBP48_06580	COG0583	DNA-binding transcription factor activity
KBP48_06585	COG3634	alkyl hydroperoxide reductase activity
KBP48_06600	COG1450	Type ii and iii secretion system protein
KBP48_06615	COG3166	PFAM Fimbrial assembly family protein
KBP48_06620	COG3156	type II secretion system protein K
KBP48_06625	COG4795	General secretion pathway protein
KBP48_06630	COG2165	general secretion pathway protein
KBP48_06635	COG4970	Tfp pilus assembly protein FimT
KBP48_06640	COG2165	general secretion pathway protein
KBP48_06645	COG1459	type II secretion system
KBP48_06650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KBP48_06655	COG5295	Hep Hag repeat protein
KBP48_06690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KBP48_06705	COG1561	YicC-like family, N-terminal region
KBP48_06730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KBP48_06775	COG0308	aminopeptidase N
KBP48_06830	COG1959	2 iron, 2 sulfur cluster binding
KBP48_06835	COG0719	Fe-S assembly protein
KBP48_06840	COG0396	ATPase activity
KBP48_06845	COG0719	Fe-S assembly protein
KBP48_06865	COG0297	glycogen (starch) synthase activity
KBP48_06870	COG0726	polysaccharide deacetylase
KBP48_06875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KBP48_06880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KBP48_06885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KBP48_06890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KBP48_06895	COG1609	Transcriptional regulator
KBP48_06925	COG1028	Short-chain dehydrogenase reductase Sdr
KBP48_06930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KBP48_06935	COG4191	Histidine kinase
KBP48_06945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KBP48_06965	COG0492	ferredoxin-NADP+ reductase activity
KBP48_06985	COG0542	response to heat
KBP48_07015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBP48_07035	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KBP48_07050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KBP48_07060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KBP48_07095	COG0271	Belongs to the BolA IbaG family
KBP48_07105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KBP48_07120	COG1137	ATPase activity
KBP48_07155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KBP48_07175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KBP48_07180	COG0629	single-stranded DNA binding
KBP48_07185	COG0142	geranyltranstransferase activity
KBP48_07190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KBP48_07195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KBP48_07200	COG1845	cytochrome c oxidase, subunit III
KBP48_07205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KBP48_07220	COG1643	Atp-dependent helicase
KBP48_07225	COG0783	Belongs to the Dps family
KBP48_07230	COG0514	ATP-dependent DNA helicase (RecQ)
KBP48_07240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KBP48_07275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KBP48_07300	COG0741	lytic transglycosylase activity
KBP48_07310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KBP48_07340	COG1846	Transcriptional regulator
KBP48_07365	COG4208	sulfate ABC transporter
KBP48_07370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KBP48_07415	COG0784	Response regulator, receiver
KBP48_07415	COG2198	Histidine kinase
KBP48_07415	COG2205	protein histidine kinase activity
KBP48_07420	COG2353	YceI-like domain
KBP48_07435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KBP48_07455	COG2894	cell division
KBP48_07475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBP48_07485	COG0772	Belongs to the SEDS family
KBP48_07490	COG0768	penicillin binding
KBP48_07495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KBP48_07500	COG1792	Involved in formation and maintenance of cell shape
KBP48_07505	COG1077	Cell shape determining protein MreB Mrl
KBP48_07600	COG0436	Aminotransferase
KBP48_07665	COG0196	riboflavin kinase activity
KBP48_07670	COG0728	peptidoglycan biosynthetic process
KBP48_07675	COG0268	Binds directly to 16S ribosomal RNA
KBP48_07695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KBP48_07715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KBP48_07720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KBP48_07735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KBP48_07745	COG0776	regulation of translation
KBP48_07790	COG0395	ABC-type sugar transport system, permease component
KBP48_07795	COG1175	transmembrane transport
KBP48_07820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KBP48_07840	COG0436	Aminotransferase
KBP48_07865	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KBP48_07875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KBP48_07905	COG5434	Belongs to the glycosyl hydrolase 28 family
KBP48_07930	COG0402	S-adenosylhomocysteine deaminase activity
KBP48_07940	COG1509	lysine 2,3-aminomutase activity
KBP48_07975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KBP48_07980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KBP48_07995	COG1028	Short-chain dehydrogenase reductase Sdr
KBP48_08065	COG0142	geranyltranstransferase activity
KBP48_08075	COG0037	tRNA processing
KBP48_08090	COG1301	dicarboxylic acid transport
KBP48_08100	COG0791	NLP P60 protein
KBP48_08105	COG0791	NLP P60 protein
KBP48_08115	COG2311	Membrane
KBP48_08130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KBP48_08250	COG0351	phosphomethylpyrimidine kinase
KBP48_08250	COG0352	thiamine-phosphate diphosphorylase activity
KBP48_08260	COG1324	tolerance protein
KBP48_08295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBP48_08300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KBP48_08305	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KBP48_08320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KBP48_08340	COG4774	siderophore transport
KBP48_08365	COG1477	protein flavinylation
KBP48_08370	COG1555	photosystem II stabilization
KBP48_08375	COG3178	'Phosphotransferase
KBP48_08380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KBP48_08390	COG0628	permease
KBP48_08405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KBP48_08430	COG3590	peptidase
KBP48_08490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KBP48_08490	COG0519	Catalyzes the synthesis of GMP from XMP
KBP48_08505	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KBP48_08520	COG3107	peptidoglycan biosynthetic process
KBP48_08540	COG2878	Part of a membrane complex involved in electron transport
KBP48_08645	COG1611	Belongs to the LOG family
KBP48_08650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KBP48_08655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KBP48_08665	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KBP48_08695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KBP48_08710	COG0330	HflC and HflK could
KBP48_08715	COG0330	HflC and HflK could
KBP48_08720	COG0604	alcohol dehydrogenase
KBP48_08750	COG1183	phosphatidylcholine synthase activity
KBP48_08770	COG0668	transmembrane transport
KBP48_08775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KBP48_08790	COG1610	YqeY-like protein
KBP48_08800	COG0358	DNA primase activity
KBP48_08835	COG1074	ATP-dependent DNA helicase activity
KBP48_08840	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KBP48_08845	COG1127	ABC transporter
KBP48_08850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KBP48_08870	COG2853	Lipoprotein
KBP48_08875	COG1322	Protein conserved in bacteria
KBP48_08880	COG1116	anion transmembrane transporter activity
KBP48_08890	COG0531	amino acid
KBP48_08895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KBP48_08900	COG0861	Integral membrane protein TerC family
KBP48_08945	COG2193	ferroxidase activity
KBP48_09025	COG2124	cytochrome p450
KBP48_09030	COG2194	sulfuric ester hydrolase activity
KBP48_09070	COG0667	Aldo Keto reductase
KBP48_09075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KBP48_09085	COG0305	Participates in initiation and elongation during chromosome replication
KBP48_09105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KBP48_09115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KBP48_09120	COG0277	FAD linked oxidase domain protein
KBP48_09130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KBP48_09135	COG4206	TonB-dependent receptor
KBP48_09215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KBP48_09235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KBP48_09265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBP48_09265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KBP48_09285	COG0488	(ABC) transporter
KBP48_09295	COG3011	Protein conserved in bacteria
KBP48_09305	COG0564	pseudouridine synthase activity
KBP48_09320	COG1918	ferrous iron import across plasma membrane
KBP48_09320	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KBP48_09330	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KBP48_09355	COG0758	DNA mediated transformation
KBP48_09400	COG2969	positive regulation of protein catabolic process
KBP48_09405	COG0625	glutathione transferase activity
KBP48_09410	COG2857	Cytochrome c1
KBP48_09415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KBP48_09420	COG0723	plastoquinol--plastocyanin reductase activity
KBP48_09435	COG1702	phosphate starvation-inducible protein PhoH
KBP48_09450	COG4535	Mg2 and Co2 transporter CorC
KBP48_09460	COG0598	Magnesium transport protein CorA
KBP48_09565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KBP48_09575	COG1199	ATP-dependent helicase activity
KBP48_09590	COG0288	reversible hydration of carbon dioxide
KBP48_09615	COG2011	ABC-type metal ion transport system permease component
KBP48_09620	COG1464	Belongs to the NlpA lipoprotein family
KBP48_09635	COG0508	dehydrogenase complex catalyzes the overall conversion of
KBP48_09640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KBP48_09655	COG0626	cystathionine gamma-synthase activity
KBP48_09660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KBP48_09665	COG0739	heme binding
KBP48_09685	COG1238	metal cluster binding
KBP48_09700	COG5002	protein histidine kinase activity
KBP48_09720	COG1388	LysM domain
KBP48_09720	COG3858	chitin binding
KBP48_09725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KBP48_09735	COG1472	Belongs to the glycosyl hydrolase 3 family
KBP48_09750	COG3537	Alpha-1,2-mannosidase
KBP48_09775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBP48_09780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KBP48_09825	COG0469	pyruvate kinase activity
KBP48_09845	COG0735	belongs to the Fur family
KBP48_09855	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBP48_09855	COG5297	Belongs to the glycosyl hydrolase family 6
KBP48_09865	COG0612	Peptidase, M16
KBP48_09880	COG4305	rare lipoprotein A
KBP48_09890	COG0739	heme binding
KBP48_09900	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KBP48_09915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KBP48_09945	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KBP48_09960	COG3116	cell division
KBP48_09975	COG0471	metal ion transport
KBP48_09975	COG3273	potassium ion transport
KBP48_10030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KBP48_10090	COG0860	N-Acetylmuramoyl-L-alanine amidase
KBP48_10095	COG0802	atpase or kinase
KBP48_10100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KBP48_10100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KBP48_10105	COG1570	exodeoxyribonuclease VII activity
KBP48_10170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KBP48_10195	COG0745	RESPONSE REGULATOR receiver
KBP48_10200	COG0642	Histidine kinase
KBP48_10210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KBP48_10255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KBP48_10270	COG2831	hemolysin activation secretion protein
KBP48_10295	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KBP48_10335	COG0316	Belongs to the HesB IscA family
KBP48_10375	COG0697	spore germination
KBP48_10380	COG0671	phosphoesterase, PA-phosphatase related
KBP48_10385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KBP48_10395	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KBP48_10400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KBP48_10415	COG1132	(ABC) transporter
KBP48_10420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KBP48_10425	COG1538	Outer membrane efflux protein
KBP48_10455	COG0745	RESPONSE REGULATOR receiver
KBP48_10460	COG4783	chaperone-mediated protein folding
KBP48_10470	COG0473	3-isopropylmalate dehydrogenase activity
KBP48_10480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KBP48_10485	COG3083	sulfuric ester hydrolase activity
KBP48_10490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KBP48_10515	COG0564	pseudouridine synthase activity
KBP48_10520	COG1530	ribonuclease E activity
KBP48_10525	COG2197	response regulator
KBP48_10540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KBP48_10555	COG0488	(ABC) transporter
KBP48_10570	COG1278	Cold shock
KBP48_10575	COG2203	Gaf domain
KBP48_10575	COG3706	GGDEF domain
KBP48_10575	COG4251	negative regulation of phosphorylation
KBP48_10575	COG5001	Diguanylate cyclase
KBP48_10585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KBP48_10615	COG0222	ribosome binding
KBP48_10630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KBP48_10635	COG0250	Participates in transcription elongation, termination and antitermination
KBP48_10640	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KBP48_10670	COG0012	GTP binding
KBP48_10685	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KBP48_10760	COG2095	MarC family integral membrane protein
KBP48_10770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KBP48_10795	COG2132	Multicopper oxidase
KBP48_10805	COG0210	DNA helicase
KBP48_10815	COG0616	signal peptide processing
KBP48_10835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KBP48_10850	COG2201	protein-glutamate methylesterase activity
KBP48_10855	COG2177	Part of the ABC transporter FtsEX involved in
KBP48_10860	COG2884	Cell division ATP-binding protein ftsE
KBP48_10865	COG0513	Belongs to the DEAD box helicase family
KBP48_10870	COG3118	belongs to the thioredoxin family
KBP48_10875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KBP48_10890	COG0793	Belongs to the peptidase S41A family
KBP48_10895	COG4942	peptidase
KBP48_10910	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KBP48_10915	COG0493	'glutamate synthase
KBP48_10920	COG0070	glutamate synthase
KBP48_10920	COG0069	glutamate synthase activity
KBP48_10920	COG0067	glutamate synthase
KBP48_10970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP48_11015	COG1280	lysine exporter protein (LysE YggA)
KBP48_11030	COG4942	peptidase
KBP48_11070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KBP48_11085	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KBP48_11225	COG1487	ribonuclease activity
KBP48_11230	COG4691	Plasmid stability protein
KBP48_11325	COG0594	ribonuclease P activity