locus-tag	class	description
HKJ33_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKJ33_00020	COG0187	DNA topoisomerase II activity
HKJ33_00030	COG0501	Belongs to the peptidase M48B family
HKJ33_00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKJ33_00155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HKJ33_00165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKJ33_00175	COG0511	ligase activity, forming carbon-carbon bonds
HKJ33_00180	COG0439	Biotin carboxylase
HKJ33_00185	COG0210	DNA helicase
HKJ33_00210	COG1040	competence protein
HKJ33_00220	COG1752	Esterase of the alpha-beta hydrolase superfamily
HKJ33_00260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HKJ33_00270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKJ33_00295	COG3121	Chaperone
HKJ33_00300	COG3539	Fimbrial protein
HKJ33_00305	COG1546	Belongs to the CinA family
HKJ33_00310	COG0477	Major facilitator Superfamily
HKJ33_00315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKJ33_00330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKJ33_00340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKJ33_00350	COG1534	Rna-binding protein
HKJ33_00380	COG1560	Kdo2-lipid A biosynthetic process
HKJ33_00385	COG1519	Transferase
HKJ33_00405	COG0336	Belongs to the RNA methyltransferase TrmD family
HKJ33_00425	COG1393	Belongs to the ArsC family
HKJ33_00435	COG0367	asparagine synthase
HKJ33_00445	COG2070	2-Nitropropane dioxygenase
HKJ33_00475	COG0339	signal peptide processing
HKJ33_00565	COG4221	oxidoreductase activity
HKJ33_00585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKJ33_00595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ33_00640	COG2223	nitrite transmembrane transporter activity
HKJ33_00650	COG0739	heme binding
HKJ33_00700	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ33_00710	COG1272	protein, Hemolysin III
HKJ33_00715	COG0463	Glycosyl transferase, family 2
HKJ33_00720	COG0084	hydrolase, TatD family'
HKJ33_00750	COG0330	HflC and HflK could
HKJ33_00755	COG3956	TIGRFAM MazG family protein
HKJ33_00765	COG0494	nUDIX hydrolase
HKJ33_00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HKJ33_00780	COG0513	Belongs to the DEAD box helicase family
HKJ33_00785	COG0720	synthase
HKJ33_00805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HKJ33_00840	COG3617	BRO family, N-terminal domain
HKJ33_00935	COG3772	lysozyme
HKJ33_01005	COG3093	addiction module antidote protein HigA
HKJ33_01125	COG0512	Glutamine amidotransferase of anthranilate synthase
HKJ33_01155	COG0006	proline dipeptidase activity
HKJ33_01175	COG1862	Preprotein translocase
HKJ33_01180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKJ33_01185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKJ33_01195	COG0617	tRNA 3'-terminal CCA addition
HKJ33_01235	COG0195	Participates in both transcription termination and antitermination
HKJ33_01265	COG1733	regulation of RNA biosynthetic process
HKJ33_01270	COG0702	epimerase
HKJ33_01315	COG2086	electron transfer activity
HKJ33_01345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ33_01375	COG0477	Major facilitator Superfamily
HKJ33_01395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HKJ33_01400	COG0671	phosphoesterase, PA-phosphatase related
HKJ33_01415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKJ33_01420	COG0628	permease
HKJ33_01440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKJ33_01445	COG1090	epimerase
HKJ33_01450	COG0318	PFAM AMP-dependent synthetase and ligase
HKJ33_01470	COG1049	propionate catabolic process, 2-methylcitrate cycle
HKJ33_01520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ33_01545	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKJ33_01565	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HKJ33_01570	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HKJ33_01575	COG1034	ATP synthesis coupled electron transport
HKJ33_01610	COG1007	ATP synthesis coupled electron transport
HKJ33_01615	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ33_01620	COG2851	Citrate transporter
HKJ33_01635	COG0642	Histidine kinase
HKJ33_01655	COG2205	protein histidine kinase activity
HKJ33_01655	COG0784	Response regulator, receiver
HKJ33_01675	COG0281	malic enzyme
HKJ33_01675	COG0280	phosphate acetyltransferase
HKJ33_01685	COG0742	ribosomal rna small subunit methyltransferase
HKJ33_01700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HKJ33_01710	COG3706	GGDEF domain
HKJ33_01720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HKJ33_01745	COG2166	iron-sulfur cluster assembly
HKJ33_01775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HKJ33_01845	COG1914	H( )-stimulated, divalent metal cation uptake system
HKJ33_01860	COG1946	Acyl-CoA thioesterase
HKJ33_01945	COG0750	zinc metalloprotease
HKJ33_01955	COG0575	Belongs to the CDS family
HKJ33_01960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKJ33_01995	COG0528	UMP kinase activity
HKJ33_02040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKJ33_02050	COG0354	folic acid binding
HKJ33_02060	COG2009	succinate dehydrogenase
HKJ33_02065	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HKJ33_02075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HKJ33_02105	COG0811	peptide transport
HKJ33_02180	COG3077	Addiction module antitoxin, RelB DinJ family
HKJ33_02255	COG3772	lysozyme
HKJ33_02330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKJ33_02380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKJ33_02380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKJ33_02410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HKJ33_02435	COG1024	Enoyl-CoA hydratase
HKJ33_02440	COG0527	aspartate kinase activity
HKJ33_02460	COG0494	nUDIX hydrolase
HKJ33_02465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HKJ33_02475	COG0424	maF-like protein
HKJ33_02480	COG1530	ribonuclease E activity
HKJ33_02490	COG0312	modulator of DNA gyrase
HKJ33_02500	COG0312	modulator of DNA gyrase
HKJ33_02505	COG0583	DNA-binding transcription factor activity
HKJ33_02520	COG1064	alcohol dehydrogenase
HKJ33_02575	COG0356	it plays a direct role in the translocation of protons across the membrane
HKJ33_02630	COG0255	Belongs to the universal ribosomal protein uL29 family
HKJ33_02690	COG0201	protein transport
HKJ33_02720	COG2960	long-chain fatty acid transporting porin activity
HKJ33_02725	COG0606	chelatase, subunit chli
HKJ33_02745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HKJ33_02805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKJ33_02810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKJ33_02825	COG1187	pseudouridine synthase activity
HKJ33_02830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HKJ33_02850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKJ33_02855	COG0625	glutathione transferase activity
HKJ33_02865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKJ33_02910	COG0842	Transport permease protein
HKJ33_02915	COG1131	(ABC) transporter
HKJ33_02940	COG1643	Atp-dependent helicase
HKJ33_02955	COG1956	GAF domain-containing protein
HKJ33_02965	COG0729	surface antigen
HKJ33_02970	COG2911	Protein conserved in bacteria
HKJ33_03025	COG3657	addiction module killer protein
HKJ33_03030	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKJ33_03060	COG3657	addiction module killer protein
HKJ33_03065	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKJ33_03130	COG2369	cell adhesion
HKJ33_03175	COG3772	lysozyme
HKJ33_03190	COG0305	Participates in initiation and elongation during chromosome replication
HKJ33_03205	COG3617	BRO family, N-terminal domain
HKJ33_03230	COG4197	protein conserved in bacteria, prophage-related
HKJ33_03300	COG5532	Uncharacterized conserved protein (DUF2303)
HKJ33_03320	COG0629	single-stranded DNA binding
HKJ33_03445	COG0668	transmembrane transport
HKJ33_03475	COG5297	Belongs to the glycosyl hydrolase family 6
HKJ33_03510	COG2733	membrane
HKJ33_03515	COG1253	flavin adenine dinucleotide binding
HKJ33_03565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HKJ33_03580	COG0644	oxidoreductase
HKJ33_03580	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HKJ33_03595	COG3218	ABC-type transport auxiliary lipoprotein component
HKJ33_03595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HKJ33_03600	COG1127	ABC transporter
HKJ33_03605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HKJ33_03645	COG0629	single-stranded DNA binding
HKJ33_03670	COG4969	Belongs to the N-Me-Phe pilin family
HKJ33_03785	COG0675	Transposase, IS605 OrfB family
HKJ33_03820	COG1077	Cell shape determining protein MreB Mrl
HKJ33_03825	COG1792	Involved in formation and maintenance of cell shape
HKJ33_03830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HKJ33_03835	COG0768	penicillin binding
HKJ33_03840	COG0772	Belongs to the SEDS family
HKJ33_03850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKJ33_03870	COG2894	cell division
HKJ33_03890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKJ33_03905	COG2353	YceI-like domain
HKJ33_03955	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HKJ33_03960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HKJ33_03965	COG4208	sulfate ABC transporter
HKJ33_03990	COG1846	Transcriptional regulator
HKJ33_04020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HKJ33_04030	COG0741	lytic transglycosylase activity
HKJ33_04060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKJ33_04095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKJ33_04105	COG0514	ATP-dependent DNA helicase (RecQ)
HKJ33_04110	COG0783	Belongs to the Dps family
HKJ33_04115	COG1643	Atp-dependent helicase
HKJ33_04125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HKJ33_04130	COG1845	cytochrome c oxidase, subunit III
HKJ33_04135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKJ33_04140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HKJ33_04145	COG0142	geranyltranstransferase activity
HKJ33_04150	COG0629	single-stranded DNA binding
HKJ33_04190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKJ33_04225	COG1137	ATPase activity
HKJ33_04240	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HKJ33_04250	COG0271	Belongs to the BolA IbaG family
HKJ33_04290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HKJ33_04300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKJ33_04315	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HKJ33_04335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HKJ33_04365	COG0542	response to heat
HKJ33_04385	COG0492	ferredoxin-NADP+ reductase activity
HKJ33_04405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HKJ33_04415	COG4191	Histidine kinase
HKJ33_04420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKJ33_04425	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ33_04455	COG1609	Transcriptional regulator
HKJ33_04460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HKJ33_04465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKJ33_04470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKJ33_04475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ33_04480	COG0726	polysaccharide deacetylase
HKJ33_04485	COG0297	glycogen (starch) synthase activity
HKJ33_04500	COG0719	Fe-S assembly protein
HKJ33_04505	COG0396	ATPase activity
HKJ33_04510	COG0719	Fe-S assembly protein
HKJ33_04515	COG1959	2 iron, 2 sulfur cluster binding
HKJ33_04705	COG3772	lysozyme
HKJ33_04810	COG3617	BRO family, N-terminal domain
HKJ33_04850	COG0308	aminopeptidase N
HKJ33_04895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKJ33_04920	COG1561	YicC-like family, N-terminal region
HKJ33_04935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HKJ33_04970	COG5295	Hep Hag repeat protein
HKJ33_04975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKJ33_04980	COG1459	type II secretion system
HKJ33_04985	COG2165	general secretion pathway protein
HKJ33_04990	COG4970	Tfp pilus assembly protein FimT
HKJ33_04995	COG2165	general secretion pathway protein
HKJ33_05000	COG4795	General secretion pathway protein
HKJ33_05005	COG3156	type II secretion system protein K
HKJ33_05010	COG3166	PFAM Fimbrial assembly family protein
HKJ33_05025	COG1450	Type ii and iii secretion system protein
HKJ33_05040	COG3634	alkyl hydroperoxide reductase activity
HKJ33_05045	COG0583	DNA-binding transcription factor activity
HKJ33_05110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HKJ33_05130	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKJ33_05135	COG0567	Dehydrogenase, E1 component
HKJ33_05140	COG2850	peptidyl-arginine hydroxylation
HKJ33_05250	COG3772	lysozyme
HKJ33_05345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKJ33_05350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ33_05355	COG2902	Dehydrogenase
HKJ33_05395	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ33_05425	COG1472	Belongs to the glycosyl hydrolase 3 family
HKJ33_05445	COG2925	Exonuclease
HKJ33_05460	COG0025	NhaP-type Na H and K H
HKJ33_05480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKJ33_05505	COG0006	proline dipeptidase activity
HKJ33_05515	COG0778	Nitroreductase
HKJ33_05550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HKJ33_05585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKJ33_05600	COG0557	exoribonuclease II activity
HKJ33_05610	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKJ33_05625	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HKJ33_05630	COG1289	transmembrane transporter activity
HKJ33_05655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HKJ33_05665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKJ33_05685	COG0596	Alpha beta hydrolase
HKJ33_05690	COG0727	PFAM Uncharacterised protein family (UPF0153)
HKJ33_05695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HKJ33_05695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HKJ33_05735	COG0840	transmembrane signaling receptor activity
HKJ33_05740	COG0784	Response regulator, receiver
HKJ33_05740	COG0643	Histidine kinase
HKJ33_05740	COG2198	Histidine kinase
HKJ33_05770	COG0285	dihydrofolate synthase activity
HKJ33_05780	COG0339	signal peptide processing
HKJ33_05800	COG1301	dicarboxylic acid transport
HKJ33_05805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKJ33_05815	COG2091	lysine biosynthetic process via aminoadipic acid
HKJ33_05850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKJ33_05885	COG0084	hydrolase, TatD family'
HKJ33_05900	COG0552	protein localization to endoplasmic reticulum
HKJ33_05945	COG0824	Thioesterase
HKJ33_05970	COG2885	chlorophyll binding
HKJ33_05980	COG0602	queuosine metabolic process
HKJ33_05995	COG3104	oligopeptide transport
HKJ33_06000	COG0386	Belongs to the glutathione peroxidase family
HKJ33_06020	COG0406	alpha-ribazole phosphatase activity
HKJ33_06245	COG3852	Histidine kinase
HKJ33_06250	COG2204	response regulator
HKJ33_06265	COG0004	ammonium transporteR
HKJ33_06270	COG0347	Belongs to the P(II) protein family
HKJ33_06275	COG0174	glutamine synthetase
HKJ33_06280	COG1968	undecaprenyl-diphosphatase activity
HKJ33_06285	COG2353	YceI-like domain
HKJ33_06390	COG3772	lysozyme
HKJ33_06490	COG3617	BRO family, N-terminal domain
HKJ33_06520	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HKJ33_06570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HKJ33_06575	COG1764	response to oxidative stress
HKJ33_06580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ33_06590	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKJ33_06615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKJ33_06625	COG1399	metal-binding, possibly nucleic acid-binding protein
HKJ33_06635	COG0714	Associated with various cellular activities
HKJ33_06655	COG0537	adenosine 5'-monophosphoramidase activity
HKJ33_06705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKJ33_06735	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKJ33_06760	COG4969	Belongs to the N-Me-Phe pilin family
HKJ33_06775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKJ33_06780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKJ33_06790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKJ33_06800	COG0251	oxidation-reduction process
HKJ33_06805	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKJ33_06805	COG0392	lysyltransferase activity
HKJ33_06815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HKJ33_06825	COG0463	Glycosyl transferase, family 2
HKJ33_06870	COG3275	phosphorelay sensor kinase activity
HKJ33_06875	COG0400	carboxylic ester hydrolase activity
HKJ33_06895	COG2226	methyltransferase
HKJ33_06910	COG2027	D-alanyl-D-alanine carboxypeptidase
HKJ33_06925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKJ33_06960	COG1131	(ABC) transporter
HKJ33_07085	COG2369	cell adhesion
HKJ33_07090	COG3567	Phage-associated protein, HI1409 family
HKJ33_07120	COG3772	lysozyme
HKJ33_07190	COG0489	protein tyrosine kinase activity
HKJ33_07200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKJ33_07280	COG0489	protein tyrosine kinase activity
HKJ33_07290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKJ33_07350	COG0488	(ABC) transporter
HKJ33_07370	COG4651	solute:proton antiporter activity
HKJ33_07370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HKJ33_07435	COG0859	PFAM glycosyl transferase family 9
HKJ33_07450	COG0631	protein serine/threonine phosphatase activity
HKJ33_07455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKJ33_07460	COG0328	RNA-DNA hybrid ribonuclease activity
HKJ33_07485	COG2183	response to ionizing radiation
HKJ33_07500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HKJ33_07505	COG3118	belongs to the thioredoxin family
HKJ33_07560	COG2951	lytic endotransglycosylase activity
HKJ33_07565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKJ33_07690	COG0277	FAD linked oxidase domain protein
HKJ33_07695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HKJ33_07700	COG0531	amino acid
HKJ33_07705	COG0531	amino acid
HKJ33_07785	COG0460	homoserine dehydrogenase
HKJ33_07785	COG0527	aspartate kinase activity
HKJ33_07790	COG0540	Belongs to the ATCase OTCase family
HKJ33_07805	COG1686	Belongs to the peptidase S11 family
HKJ33_07830	COG4953	penicillin-binding protein 1C
HKJ33_07855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKJ33_07925	COG1506	peptidase
HKJ33_07925	COG0823	Involved in the tonB-independent uptake of proteins
HKJ33_07930	COG1297	OPT oligopeptide transporter protein
HKJ33_07960	COG0676	glucose-6-phosphate 1-epimerase activity
HKJ33_07970	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKJ33_07975	COG1335	isochorismatase
HKJ33_07980	COG0318	PFAM AMP-dependent synthetase and ligase
HKJ33_07990	COG0463	Glycosyl transferase, family 2
HKJ33_08005	COG1192	Involved in chromosome partitioning
HKJ33_08065	COG3772	lysozyme
HKJ33_08125	COG1605	Chorismate mutase
HKJ33_08125	COG0077	Prephenate dehydratase
HKJ33_08140	COG1668	transmembrane transport
HKJ33_08145	COG4555	ABC transporter
HKJ33_08170	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HKJ33_08185	COG0287	Prephenate dehydrogenase
HKJ33_08185	COG1605	Chorismate mutase
HKJ33_08210	COG0497	DNA recombination
HKJ33_08220	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKJ33_08225	COG2914	Belongs to the UPF0125 (RnfH) family
HKJ33_08245	COG1278	Cold shock
HKJ33_08265	COG2954	triphosphatase activity
HKJ33_08275	COG0745	RESPONSE REGULATOR receiver
HKJ33_08280	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HKJ33_08285	COG0438	transferase activity, transferring glycosyl groups
HKJ33_08300	COG0438	transferase activity, transferring glycosyl groups
HKJ33_08365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ33_08370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKJ33_08385	COG1064	alcohol dehydrogenase
HKJ33_08405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HKJ33_08430	COG3609	addiction module antidote protein, CC2985 family
HKJ33_08440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HKJ33_08445	COG0675	Transposase, IS605 OrfB family
HKJ33_08455	COG0436	Aminotransferase
HKJ33_08520	COG0196	riboflavin kinase activity
HKJ33_08525	COG0728	peptidoglycan biosynthetic process
HKJ33_08530	COG0268	Binds directly to 16S ribosomal RNA
HKJ33_08550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKJ33_08570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKJ33_08575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HKJ33_08590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HKJ33_08600	COG0776	regulation of translation
HKJ33_08645	COG0395	ABC-type sugar transport system, permease component
HKJ33_08650	COG1175	transmembrane transport
HKJ33_08675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKJ33_08695	COG0436	Aminotransferase
HKJ33_08700	COG4133	protoheme IX ABC transporter activity
HKJ33_08720	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HKJ33_08730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HKJ33_08760	COG5434	Belongs to the glycosyl hydrolase 28 family
HKJ33_08780	COG0402	S-adenosylhomocysteine deaminase activity
HKJ33_08790	COG1509	lysine 2,3-aminomutase activity
HKJ33_08830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKJ33_08835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKJ33_08850	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ33_08895	COG0142	geranyltranstransferase activity
HKJ33_08905	COG0037	tRNA processing
HKJ33_08920	COG1301	dicarboxylic acid transport
HKJ33_08925	COG0791	NLP P60 protein
HKJ33_08930	COG0791	NLP P60 protein
HKJ33_08940	COG2311	Membrane
HKJ33_08955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKJ33_09080	COG0352	thiamine-phosphate diphosphorylase activity
HKJ33_09080	COG0351	phosphomethylpyrimidine kinase
HKJ33_09090	COG1324	tolerance protein
HKJ33_09125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ33_09130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ33_09135	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HKJ33_09150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HKJ33_09170	COG4774	siderophore transport
HKJ33_09195	COG1477	protein flavinylation
HKJ33_09200	COG1555	photosystem II stabilization
HKJ33_09205	COG3178	'Phosphotransferase
HKJ33_09210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HKJ33_09220	COG0628	permease
HKJ33_09230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HKJ33_09235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKJ33_09260	COG3590	peptidase
HKJ33_09315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HKJ33_09315	COG0519	Catalyzes the synthesis of GMP from XMP
HKJ33_09330	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HKJ33_09345	COG3107	peptidoglycan biosynthetic process
HKJ33_09365	COG2878	Part of a membrane complex involved in electron transport
HKJ33_09420	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HKJ33_09475	COG1611	Belongs to the LOG family
HKJ33_09480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HKJ33_09485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HKJ33_09495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKJ33_09525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HKJ33_09540	COG0330	HflC and HflK could
HKJ33_09545	COG0330	HflC and HflK could
HKJ33_09550	COG0604	alcohol dehydrogenase
HKJ33_09580	COG1183	phosphatidylcholine synthase activity
HKJ33_09600	COG0668	transmembrane transport
HKJ33_09605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKJ33_09620	COG1610	YqeY-like protein
HKJ33_09630	COG0358	DNA primase activity
HKJ33_09665	COG1074	ATP-dependent DNA helicase activity
HKJ33_09670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HKJ33_09675	COG1127	ABC transporter
HKJ33_09680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HKJ33_09700	COG2853	Lipoprotein
HKJ33_09710	COG1322	Protein conserved in bacteria
HKJ33_09715	COG1116	anion transmembrane transporter activity
HKJ33_09725	COG0531	amino acid
HKJ33_09730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HKJ33_09735	COG0861	Integral membrane protein TerC family
HKJ33_09775	COG2193	ferroxidase activity
HKJ33_09805	COG2205	protein histidine kinase activity
HKJ33_09810	COG0745	RESPONSE REGULATOR receiver
HKJ33_09820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKJ33_09845	COG0542	response to heat
HKJ33_09855	COG0352	thiamine-phosphate diphosphorylase activity
HKJ33_09860	COG2124	cytochrome p450
HKJ33_09865	COG2194	sulfuric ester hydrolase activity
HKJ33_09905	COG0667	Aldo Keto reductase
HKJ33_09910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKJ33_09920	COG0305	Participates in initiation and elongation during chromosome replication
HKJ33_09940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKJ33_09950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKJ33_09955	COG0277	FAD linked oxidase domain protein
HKJ33_09965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HKJ33_09970	COG4206	TonB-dependent receptor
HKJ33_10055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKJ33_10075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKJ33_10105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKJ33_10105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKJ33_10125	COG0488	(ABC) transporter
HKJ33_10135	COG3011	Protein conserved in bacteria
HKJ33_10145	COG0564	pseudouridine synthase activity
HKJ33_10170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKJ33_10195	COG0758	DNA mediated transformation
HKJ33_10240	COG2969	positive regulation of protein catabolic process
HKJ33_10245	COG0625	glutathione transferase activity
HKJ33_10250	COG2857	Cytochrome c1
HKJ33_10255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HKJ33_10260	COG0723	plastoquinol--plastocyanin reductase activity
HKJ33_10265	COG0741	lytic transglycosylase activity
HKJ33_10275	COG1702	phosphate starvation-inducible protein PhoH
HKJ33_10290	COG4535	Mg2 and Co2 transporter CorC
HKJ33_10300	COG0598	Magnesium transport protein CorA
HKJ33_10375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKJ33_10385	COG1199	ATP-dependent helicase activity
HKJ33_10400	COG0288	reversible hydration of carbon dioxide
HKJ33_10425	COG2011	ABC-type metal ion transport system permease component
HKJ33_10430	COG1464	Belongs to the NlpA lipoprotein family
HKJ33_10445	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKJ33_10450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKJ33_10465	COG0626	cystathionine gamma-synthase activity
HKJ33_10470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKJ33_10475	COG0739	heme binding
HKJ33_10495	COG1238	metal cluster binding
HKJ33_10510	COG5002	protein histidine kinase activity
HKJ33_10530	COG3858	chitin binding
HKJ33_10530	COG1388	LysM domain
HKJ33_10535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HKJ33_10545	COG1472	Belongs to the glycosyl hydrolase 3 family
HKJ33_10560	COG3537	Alpha-1,2-mannosidase
HKJ33_10585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HKJ33_10590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HKJ33_10640	COG0469	pyruvate kinase activity
HKJ33_10660	COG0735	belongs to the Fur family
HKJ33_10670	COG5297	Belongs to the glycosyl hydrolase family 6
HKJ33_10670	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKJ33_10680	COG0612	Peptidase, M16
HKJ33_10700	COG4305	rare lipoprotein A
HKJ33_10710	COG0739	heme binding
HKJ33_10720	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HKJ33_10735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HKJ33_10765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HKJ33_10780	COG3116	cell division
HKJ33_10800	COG0471	metal ion transport
HKJ33_10800	COG3273	potassium ion transport
HKJ33_10855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HKJ33_10900	COG0730	response to heat
HKJ33_10920	COG0860	N-Acetylmuramoyl-L-alanine amidase
HKJ33_10925	COG0802	atpase or kinase
HKJ33_10930	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKJ33_10930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HKJ33_10935	COG1570	exodeoxyribonuclease VII activity
HKJ33_11005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKJ33_11075	COG3657	addiction module killer protein
HKJ33_11080	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKJ33_11145	COG2369	cell adhesion
HKJ33_11150	COG3567	Phage-associated protein, HI1409 family
HKJ33_11180	COG3772	lysozyme
HKJ33_11210	COG3617	BRO family, N-terminal domain
HKJ33_11215	COG3617	BRO family, N-terminal domain
HKJ33_11320	COG5532	Uncharacterized conserved protein (DUF2303)
HKJ33_11340	COG0629	single-stranded DNA binding
HKJ33_11350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HKJ33_11365	COG0745	RESPONSE REGULATOR receiver
HKJ33_11370	COG0642	Histidine kinase
HKJ33_11380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HKJ33_11425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKJ33_11435	COG2831	hemolysin activation secretion protein
HKJ33_11460	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HKJ33_11500	COG0316	Belongs to the HesB IscA family
HKJ33_11535	COG0697	spore germination
HKJ33_11540	COG0671	phosphoesterase, PA-phosphatase related
HKJ33_11545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKJ33_11555	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HKJ33_11560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKJ33_11575	COG1132	(ABC) transporter
HKJ33_11585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HKJ33_11590	COG1538	Outer membrane efflux protein
HKJ33_11620	COG0745	RESPONSE REGULATOR receiver
HKJ33_11625	COG4783	chaperone-mediated protein folding
HKJ33_11635	COG0473	3-isopropylmalate dehydrogenase activity
HKJ33_11645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKJ33_11650	COG3083	sulfuric ester hydrolase activity
HKJ33_11655	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HKJ33_11680	COG0564	pseudouridine synthase activity
HKJ33_11685	COG1530	ribonuclease E activity
HKJ33_11705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKJ33_11730	COG1278	Cold shock
HKJ33_11735	COG5001	Diguanylate cyclase
HKJ33_11735	COG3706	GGDEF domain
HKJ33_11735	COG2203	Gaf domain
HKJ33_11735	COG4251	negative regulation of phosphorylation
HKJ33_11745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKJ33_11790	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKJ33_11795	COG0250	Participates in transcription elongation, termination and antitermination
HKJ33_11800	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HKJ33_11810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKJ33_11830	COG0012	GTP binding
HKJ33_11845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKJ33_11920	COG2095	MarC family integral membrane protein
HKJ33_11925	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HKJ33_11955	COG2132	Multicopper oxidase
HKJ33_11965	COG0210	DNA helicase
HKJ33_11975	COG0616	signal peptide processing
HKJ33_11995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKJ33_12010	COG2201	protein-glutamate methylesterase activity
HKJ33_12015	COG2177	Part of the ABC transporter FtsEX involved in
HKJ33_12020	COG2884	Cell division ATP-binding protein ftsE
HKJ33_12025	COG0513	Belongs to the DEAD box helicase family
HKJ33_12030	COG3118	belongs to the thioredoxin family
HKJ33_12035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKJ33_12050	COG0793	Belongs to the peptidase S41A family
HKJ33_12055	COG4942	peptidase
HKJ33_12070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKJ33_12075	COG0493	'glutamate synthase
HKJ33_12080	COG0070	glutamate synthase
HKJ33_12080	COG0069	glutamate synthase activity
HKJ33_12080	COG0067	glutamate synthase
HKJ33_12130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKJ33_12175	COG1280	lysine exporter protein (LysE YggA)
HKJ33_12190	COG4942	peptidase
HKJ33_12240	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HKJ33_12360	COG1487	ribonuclease activity
HKJ33_12365	COG4691	Plasmid stability protein
HKJ33_12460	COG0594	ribonuclease P activity