locus-tag	class	description
B9J09_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B9J09_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B9J09_00025	COG0187	DNA topoisomerase II activity
B9J09_00035	COG0501	Belongs to the peptidase M48B family
B9J09_00075	COG0408	coproporphyrinogen oxidase activity
B9J09_00100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B9J09_00115	COG4969	Belongs to the N-Me-Phe pilin family
B9J09_00145	COG0284	orotidine-5'-phosphate decarboxylase activity
B9J09_00180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B9J09_00190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B9J09_00200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B9J09_00205	COG0511	ligase activity, forming carbon-carbon bonds
B9J09_00210	COG0439	Biotin carboxylase
B9J09_00215	COG0210	DNA helicase
B9J09_00225	COG1017	nitric oxide dioxygenase activity
B9J09_00225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9J09_00240	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B9J09_00250	COG1040	competence protein
B9J09_00255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B9J09_00260	COG1752	Esterase of the alpha-beta hydrolase superfamily
B9J09_00270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B9J09_00305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B9J09_00315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B9J09_00345	COG3121	Chaperone
B9J09_00350	COG3539	Fimbrial protein
B9J09_00355	COG1546	Belongs to the CinA family
B9J09_00360	COG0477	Major facilitator Superfamily
B9J09_00365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B9J09_00370	COG1923	regulation of RNA biosynthetic process
B9J09_00375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B9J09_00380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B9J09_00390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B9J09_00395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B9J09_00400	COG1534	Rna-binding protein
B9J09_00430	COG1560	Kdo2-lipid A biosynthetic process
B9J09_00435	COG1519	Transferase
B9J09_00445	COG0228	four-way junction DNA binding
B9J09_00450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B9J09_00455	COG0336	Belongs to the RNA methyltransferase TrmD family
B9J09_00460	COG0335	large ribosomal subunit rRNA binding
B9J09_00470	COG0024	Methionine aminopeptidase
B9J09_00480	COG2171	N-acyltransferase activity
B9J09_00485	COG1393	Belongs to the ArsC family
B9J09_00490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9J09_00495	COG0367	asparagine synthase
B9J09_00505	COG2070	2-Nitropropane dioxygenase
B9J09_00515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B9J09_00520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B9J09_00535	COG0339	signal peptide processing
B9J09_00560	COG0525	valine-tRNA ligase activity
B9J09_00600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9J09_00610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B9J09_00620	COG4221	oxidoreductase activity
B9J09_00640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B9J09_00650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9J09_00660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B9J09_00705	COG2223	nitrite transmembrane transporter activity
B9J09_00710	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B9J09_00715	COG0739	heme binding
B9J09_00720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B9J09_00750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B9J09_00765	COG1028	Short-chain dehydrogenase reductase Sdr
B9J09_00770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B9J09_00775	COG1272	protein, Hemolysin III
B9J09_00780	COG0463	Glycosyl transferase, family 2
B9J09_00785	COG0084	hydrolase, TatD family'
B9J09_00800	COG0509	glycine decarboxylation via glycine cleavage system
B9J09_00805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B9J09_00820	COG3956	TIGRFAM MazG family protein
B9J09_00825	COG1218	3'(2'),5'-bisphosphate nucleotidase
B9J09_00830	COG0494	nUDIX hydrolase
B9J09_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B9J09_00850	COG0513	Belongs to the DEAD box helicase family
B9J09_00855	COG0720	synthase
B9J09_00890	COG0825	malonyl-CoA metabolic process
B9J09_00895	COG0587	DNA-directed DNA polymerase activity
B9J09_00925	COG0512	Glutamine amidotransferase of anthranilate synthase
B9J09_00930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9J09_00935	COG0134	indole-3-glycerol-phosphate synthase activity
B9J09_00960	COG0006	proline dipeptidase activity
B9J09_00975	COG0343	queuine tRNA-ribosyltransferase activity
B9J09_00980	COG1862	Preprotein translocase
B9J09_00985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9J09_00990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9J09_01000	COG0617	tRNA 3'-terminal CCA addition
B9J09_01010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B9J09_01015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B9J09_01020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B9J09_01025	COG0166	Belongs to the GPI family
B9J09_01040	COG0779	Required for maturation of 30S ribosomal subunits
B9J09_01045	COG0195	Participates in both transcription termination and antitermination
B9J09_01050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B9J09_01055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B9J09_01060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B9J09_01065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B9J09_01070	COG1185	polyribonucleotide nucleotidyltransferase activity
B9J09_01075	COG1733	regulation of RNA biosynthetic process
B9J09_01080	COG0702	epimerase
B9J09_01140	COG2086	electron transfer activity
B9J09_01170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9J09_01205	COG0477	Major facilitator Superfamily
B9J09_01220	COG0563	adenylate kinase activity
B9J09_01225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9J09_01230	COG0671	phosphoesterase, PA-phosphatase related
B9J09_01240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B9J09_01245	COG0628	permease
B9J09_01265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9J09_01270	COG1090	epimerase
B9J09_01275	COG0318	PFAM AMP-dependent synthetase and ligase
B9J09_01305	COG1049	propionate catabolic process, 2-methylcitrate cycle
B9J09_01380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9J09_01390	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9J09_01400	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B9J09_01405	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B9J09_01410	COG1034	ATP synthesis coupled electron transport
B9J09_01420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B9J09_01430	COG0713	ATP synthesis coupled electron transport
B9J09_01445	COG1007	ATP synthesis coupled electron transport
B9J09_01450	COG1028	Short-chain dehydrogenase reductase Sdr
B9J09_01455	COG2851	Citrate transporter
B9J09_01470	COG0642	Histidine kinase
B9J09_01490	COG0675	Transposase, IS605 OrfB family
B9J09_01525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B9J09_01530	COG4206	TonB-dependent receptor
B9J09_01535	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B9J09_01555	COG0277	FAD linked oxidase domain protein
B9J09_01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9J09_01570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B9J09_01575	COG2124	cytochrome p450
B9J09_01585	COG0305	Participates in initiation and elongation during chromosome replication
B9J09_01600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9J09_01605	COG0667	Aldo Keto reductase
B9J09_01610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B9J09_01645	COG2194	sulfuric ester hydrolase activity
B9J09_01655	COG0352	thiamine-phosphate diphosphorylase activity
B9J09_01665	COG0542	response to heat
B9J09_01685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9J09_01695	COG0745	RESPONSE REGULATOR receiver
B9J09_01700	COG2205	protein histidine kinase activity
B9J09_01710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B9J09_01725	COG0494	nUDIX hydrolase
B9J09_01735	COG2193	ferroxidase activity
B9J09_01785	COG0861	Integral membrane protein TerC family
B9J09_01790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B9J09_01795	COG0531	amino acid
B9J09_01805	COG1116	anion transmembrane transporter activity
B9J09_01810	COG1322	Protein conserved in bacteria
B9J09_01820	COG2853	Lipoprotein
B9J09_01835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B9J09_01840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B9J09_01845	COG1127	ABC transporter
B9J09_01850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B9J09_01855	COG1074	ATP-dependent DNA helicase activity
B9J09_01880	COG0358	DNA primase activity
B9J09_01890	COG1610	YqeY-like protein
B9J09_01895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B9J09_01900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B9J09_01905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B9J09_01910	COG0668	transmembrane transport
B9J09_01930	COG1183	phosphatidylcholine synthase activity
B9J09_01940	COG0442	prolyl-tRNA aminoacylation
B9J09_01965	COG0604	alcohol dehydrogenase
B9J09_01970	COG0330	HflC and HflK could
B9J09_01975	COG0330	HflC and HflK could
B9J09_01985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B9J09_01990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B9J09_01995	COG0105	UTP biosynthetic process
B9J09_02000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B9J09_02020	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9J09_02025	COG1160	GTP binding
B9J09_02030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B9J09_02045	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B9J09_02050	COG1611	Belongs to the LOG family
B9J09_02055	COG4968	Prepilin-type N-terminal cleavage methylation domain
B9J09_02150	COG2878	Part of a membrane complex involved in electron transport
B9J09_02155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9J09_02155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9J09_02165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B9J09_02170	COG3107	peptidoglycan biosynthetic process
B9J09_02180	COG1162	GTPase activity
B9J09_02185	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B9J09_02200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B9J09_02200	COG0519	Catalyzes the synthesis of GMP from XMP
B9J09_02230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B9J09_02245	COG0037	tRNA processing
B9J09_02255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9J09_02270	COG3590	peptidase
B9J09_02295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B9J09_02305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B9J09_02315	COG0628	permease
B9J09_02325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B9J09_02330	COG3178	'Phosphotransferase
B9J09_02335	COG1555	photosystem II stabilization
B9J09_02340	COG1477	protein flavinylation
B9J09_02360	COG3128	pkhd-type hydroxylase
B9J09_02365	COG4774	siderophore transport
B9J09_02385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9J09_02400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B9J09_02405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9J09_02410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9J09_02435	COG0459	protein refolding
B9J09_02445	COG1324	tolerance protein
B9J09_02455	COG0351	phosphomethylpyrimidine kinase
B9J09_02455	COG0352	thiamine-phosphate diphosphorylase activity
B9J09_02465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B9J09_02520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B9J09_02535	COG2311	Membrane
B9J09_02545	COG0791	NLP P60 protein
B9J09_02550	COG0791	NLP P60 protein
B9J09_02560	COG1301	dicarboxylic acid transport
B9J09_02570	COG0037	tRNA processing
B9J09_02575	COG1722	exodeoxyribonuclease VII activity
B9J09_02580	COG0142	geranyltranstransferase activity
B9J09_02620	COG1028	Short-chain dehydrogenase reductase Sdr
B9J09_02635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9J09_02640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B9J09_02665	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B9J09_02670	COG0483	inositol monophosphate 1-phosphatase activity
B9J09_02680	COG1509	lysine 2,3-aminomutase activity
B9J09_02690	COG0402	S-adenosylhomocysteine deaminase activity
B9J09_02700	COG0546	phosphoglycolate phosphatase activity
B9J09_02715	COG5434	Belongs to the glycosyl hydrolase 28 family
B9J09_02720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9J09_02740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9J09_02745	COG1138	Cytochrome C-type biogenesis protein
B9J09_02750	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
B9J09_02770	COG4133	protoheme IX ABC transporter activity
B9J09_02775	COG0436	Aminotransferase
B9J09_02790	COG1187	pseudouridine synthase activity
B9J09_02795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B9J09_02800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B9J09_02825	COG1175	transmembrane transport
B9J09_02830	COG0395	ABC-type sugar transport system, permease component
B9J09_02860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B9J09_02865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B9J09_02875	COG0776	regulation of translation
B9J09_02885	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B9J09_02900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9J09_02905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B9J09_02915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B9J09_02915	COG0519	Catalyzes the synthesis of GMP from XMP
B9J09_02930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9J09_02935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B9J09_02940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B9J09_02945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B9J09_02950	COG0268	Binds directly to 16S ribosomal RNA
B9J09_02955	COG0728	peptidoglycan biosynthetic process
B9J09_02960	COG0196	riboflavin kinase activity
B9J09_02965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B9J09_03090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B9J09_03105	COG3757	hydrolase, family 25
B9J09_03105	COG3409	Peptidoglycan-binding domain 1 protein
B9J09_03115	COG1064	alcohol dehydrogenase
B9J09_03130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9J09_03135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9J09_03140	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B9J09_03140	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B9J09_03160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B9J09_03165	COG0066	3-isopropylmalate dehydratase activity
B9J09_03170	COG0473	3-isopropylmalate dehydrogenase activity
B9J09_03200	COG0438	transferase activity, transferring glycosyl groups
B9J09_03220	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
B9J09_03225	COG0745	RESPONSE REGULATOR receiver
B9J09_03255	COG1278	Cold shock
B9J09_03265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B9J09_03275	COG2914	Belongs to the UPF0125 (RnfH) family
B9J09_03280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9J09_03290	COG0497	DNA recombination
B9J09_03295	COG1420	regulation of RNA biosynthetic process
B9J09_03300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B9J09_03305	COG0443	Heat shock 70 kDa protein
B9J09_03310	COG0484	heat shock protein binding
B9J09_03315	COG1605	Chorismate mutase
B9J09_03315	COG0287	Prephenate dehydrogenase
B9J09_03335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B9J09_03360	COG4555	ABC transporter
B9J09_03365	COG1668	transmembrane transport
B9J09_03375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B9J09_03380	COG0077	Prephenate dehydratase
B9J09_03380	COG1605	Chorismate mutase
B9J09_03385	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B9J09_03440	COG0322	excinuclease ABC activity
B9J09_03445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B9J09_03480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B9J09_03485	COG0489	protein tyrosine kinase activity
B9J09_03490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B9J09_03495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9J09_03550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B9J09_03560	COG1192	Involved in chromosome partitioning
B9J09_03565	COG1475	DNA binding
B9J09_03575	COG0463	Glycosyl transferase, family 2
B9J09_03585	COG0318	PFAM AMP-dependent synthetase and ligase
B9J09_03595	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B9J09_03610	COG0676	glucose-6-phosphate 1-epimerase activity
B9J09_03620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B9J09_03625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B9J09_03640	COG1297	OPT oligopeptide transporter protein
B9J09_03650	COG0823	Involved in the tonB-independent uptake of proteins
B9J09_03650	COG1506	peptidase
B9J09_03655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9J09_03670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9J09_03680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9J09_03685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B9J09_03690	COG1381	Involved in DNA repair and RecF pathway recombination
B9J09_03695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B9J09_03700	COG0571	ribonuclease III activity
B9J09_03720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9J09_03745	COG4953	penicillin-binding protein 1C
B9J09_03760	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B9J09_03770	COG1686	Belongs to the peptidase S11 family
B9J09_03780	COG1678	Uncharacterized ACR, COG1678
B9J09_03790	COG0540	Belongs to the ATCase OTCase family
B9J09_03795	COG0460	homoserine dehydrogenase
B9J09_03795	COG0527	aspartate kinase activity
B9J09_03800	COG0083	homoserine kinase activity
B9J09_03810	COG0124	histidyl-tRNA synthetase
B9J09_03820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B9J09_03825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B9J09_03835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B9J09_03835	COG0131	Imidazoleglycerol-phosphate dehydratase
B9J09_03845	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B9J09_03860	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
B9J09_03865	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B9J09_03870	COG0235	Class ii aldolase
B9J09_03875	COG0531	amino acid
B9J09_03880	COG0531	amino acid
B9J09_03885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9J09_03890	COG0277	FAD linked oxidase domain protein
B9J09_03895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B9J09_03905	COG2264	protein methyltransferase activity
B9J09_03990	COG2951	lytic endotransglycosylase activity
B9J09_04015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B9J09_04030	COG0495	leucyl-tRNA aminoacylation
B9J09_04040	COG3118	belongs to the thioredoxin family
B9J09_04050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B9J09_04065	COG2183	response to ionizing radiation
B9J09_04080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9J09_04090	COG0328	RNA-DNA hybrid ribonuclease activity
B9J09_04095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9J09_04100	COG0631	protein serine/threonine phosphatase activity
B9J09_04115	COG0859	PFAM glycosyl transferase family 9
B9J09_04120	COG3642	lipopolysaccharide core region biosynthetic process
B9J09_04135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B9J09_04140	COG2967	ApaG domain
B9J09_04145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B9J09_04150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9J09_04155	COG0704	Plays a role in the regulation of phosphate uptake
B9J09_04160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B9J09_04165	COG0581	inorganic phosphate transmembrane transporter activity
B9J09_04170	COG0573	inorganic phosphate transmembrane transporter activity
B9J09_04175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B9J09_04180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9J09_04180	COG4651	solute:proton antiporter activity
B9J09_04195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B9J09_04205	COG0488	(ABC) transporter
B9J09_04255	COG0358	DNA primase activity
B9J09_04365	COG0445	tRNA wobble uridine modification
B9J09_04405	COG1469	GTP cyclohydrolase I activity
B9J09_04410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9J09_04415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9J09_04420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9J09_04430	COG2902	Dehydrogenase
B9J09_04435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B9J09_04475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9J09_04480	COG4221	oxidoreductase activity
B9J09_04485	COG3077	Addiction module antitoxin, RelB DinJ family
B9J09_04490	COG3041	Addiction module toxin RelE StbE family
B9J09_04565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B9J09_04590	COG2925	Exonuclease
B9J09_04605	COG0025	NhaP-type Na H and K H
B9J09_04615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B9J09_04625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B9J09_04645	COG3079	Belongs to the UPF0149 family
B9J09_04650	COG0006	proline dipeptidase activity
B9J09_04695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9J09_04700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B9J09_04735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B9J09_04740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9J09_04750	COG0557	exoribonuclease II activity
B9J09_04760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9J09_04765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9J09_04770	COG0302	gtp cyclohydrolase
B9J09_04780	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B9J09_04785	COG1289	transmembrane transporter activity
B9J09_04795	COG0151	Belongs to the GarS family
B9J09_04800	COG0138	bifunctional purine biosynthesis protein purh
B9J09_04815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B9J09_04825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9J09_04845	COG0596	Alpha beta hydrolase
B9J09_04865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B9J09_04865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9J09_04890	COG0189	ligase activity
B9J09_04905	COG0840	transmembrane signaling receptor activity
B9J09_04940	COG0285	dihydrofolate synthase activity
B9J09_04950	COG0339	signal peptide processing
B9J09_04975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9J09_04980	COG1301	dicarboxylic acid transport
B9J09_04985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B9J09_04990	COG0357	Ribosomal RNA small subunit methyltransferase G
B9J09_04995	COG2091	lysine biosynthetic process via aminoadipic acid
B9J09_05065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B9J09_05075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9J09_05115	COG0084	hydrolase, TatD family'
B9J09_05130	COG0552	protein localization to endoplasmic reticulum
B9J09_05140	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B9J09_05150	COG0217	transcriptional regulatory protein
B9J09_05155	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B9J09_05160	COG0632	four-way junction helicase activity
B9J09_05165	COG3158	transport of potassium into the cell
B9J09_05170	COG2255	four-way junction helicase activity
B9J09_05175	COG0824	Thioesterase
B9J09_05195	COG0823	Involved in the tonB-independent uptake of proteins
B9J09_05200	COG2885	chlorophyll binding
B9J09_05210	COG0602	queuosine metabolic process
B9J09_05215	COG0588	phosphoglycerate mutase activity
B9J09_05220	COG1515	deoxyribonuclease V activity
B9J09_05225	COG3104	oligopeptide transport
B9J09_05240	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B9J09_05250	COG0406	alpha-ribazole phosphatase activity
B9J09_05640	COG2337	Toxic component of a toxin-antitoxin (TA) module
B9J09_05665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B9J09_05670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B9J09_05705	COG0675	Transposase, IS605 OrfB family
B9J09_05795	COG3772	lysozyme
B9J09_05915	COG3617	BRO family, N-terminal domain
B9J09_05945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B9J09_05950	COG3852	Histidine kinase
B9J09_05955	COG2204	response regulator
B9J09_05965	COG0004	ammonium transporteR
B9J09_05970	COG0347	Belongs to the P(II) protein family
B9J09_05975	COG0174	glutamine synthetase
B9J09_05980	COG1968	undecaprenyl-diphosphatase activity
B9J09_05985	COG2353	YceI-like domain
B9J09_06005	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B9J09_06040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B9J09_06045	COG1764	response to oxidative stress
B9J09_06050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9J09_06060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B9J09_06080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9J09_06085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9J09_06090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B9J09_06095	COG1399	metal-binding, possibly nucleic acid-binding protein
B9J09_06105	COG0714	Associated with various cellular activities
B9J09_06125	COG0537	adenosine 5'-monophosphoramidase activity
B9J09_06135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B9J09_06155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B9J09_06175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9J09_06205	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B9J09_06240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B9J09_06245	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B9J09_06250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9J09_06255	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B9J09_06270	COG0251	oxidation-reduction process
B9J09_06310	COG3657	addiction module killer protein
B9J09_06315	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9J09_06410	COG2369	cell adhesion
B9J09_06425	COG3567	Phage-associated protein, HI1409 family
B9J09_06430	COG5410	chromosome segregation
B9J09_06455	COG3772	lysozyme
B9J09_06480	COG0305	Participates in initiation and elongation during chromosome replication
B9J09_06505	COG3617	BRO family, N-terminal domain
B9J09_06510	COG3617	BRO family, N-terminal domain
B9J09_06630	COG0629	single-stranded DNA binding
B9J09_06640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B9J09_06645	COG0392	lysyltransferase activity
B9J09_06645	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B9J09_06660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9J09_06670	COG0463	Glycosyl transferase, family 2
B9J09_06725	COG3275	phosphorelay sensor kinase activity
B9J09_06735	COG2943	transferase activity, transferring hexosyl groups
B9J09_06750	COG2226	methyltransferase
B9J09_06765	COG2027	D-alanyl-D-alanine carboxypeptidase
B9J09_06775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9J09_06790	COG2900	Belongs to the SlyX family
B9J09_06805	COG0386	Belongs to the glutathione peroxidase family
B9J09_06815	COG1131	(ABC) transporter
B9J09_06835	COG3657	addiction module killer protein
B9J09_06840	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9J09_06895	COG3657	addiction module killer protein
B9J09_06900	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9J09_06995	COG2369	cell adhesion
B9J09_07010	COG3567	Phage-associated protein, HI1409 family
B9J09_07015	COG5410	chromosome segregation
B9J09_07040	COG3772	lysozyme
B9J09_07080	COG0629	single-stranded DNA binding
B9J09_07090	COG0114	fumarate hydratase activity
B9J09_07105	COG2850	peptidyl-arginine hydroxylation
B9J09_07110	COG0567	Dehydrogenase, E1 component
B9J09_07135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B9J09_07150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B9J09_07155	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B9J09_07160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B9J09_07175	COG0254	rRNA binding
B9J09_07185	COG0583	DNA-binding transcription factor activity
B9J09_07190	COG3634	alkyl hydroperoxide reductase activity
B9J09_07195	COG0450	alkyl hydroperoxide reductase
B9J09_07210	COG1450	Type ii and iii secretion system protein
B9J09_07225	COG3166	PFAM Fimbrial assembly family protein
B9J09_07230	COG3156	type II secretion system protein K
B9J09_07235	COG4795	General secretion pathway protein
B9J09_07240	COG2165	general secretion pathway protein
B9J09_07245	COG4970	Tfp pilus assembly protein FimT
B9J09_07250	COG2165	general secretion pathway protein
B9J09_07255	COG1459	type II secretion system
B9J09_07260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B9J09_07265	COG5295	Hep Hag repeat protein
B9J09_07285	COG2890	protein-(glutamine-N5) methyltransferase activity
B9J09_07290	COG0596	Alpha beta hydrolase
B9J09_07305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9J09_07320	COG1561	YicC-like family, N-terminal region
B9J09_07325	COG0194	GDP metabolic process
B9J09_07330	COG1758	RNA polymerase activity
B9J09_07335	COG0529	Catalyzes the synthesis of activated sulfate
B9J09_07335	COG2895	sulfate adenylyltransferase (ATP) activity
B9J09_07340	COG0175	sulfate reduction
B9J09_07345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B9J09_07355	COG0175	sulfate reduction
B9J09_07370	COG2912	Transglutaminase-like superfamily
B9J09_07390	COG0308	aminopeptidase N
B9J09_07395	COG2226	methyltransferase
B9J09_07405	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B9J09_07415	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B9J09_07425	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B9J09_07445	COG1959	2 iron, 2 sulfur cluster binding
B9J09_07450	COG0719	Fe-S assembly protein
B9J09_07455	COG0396	ATPase activity
B9J09_07460	COG0719	Fe-S assembly protein
B9J09_07465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9J09_07480	COG0297	glycogen (starch) synthase activity
B9J09_07485	COG0726	polysaccharide deacetylase
B9J09_07490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9J09_07500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B9J09_07505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9J09_07510	COG1609	Transcriptional regulator
B9J09_07525	COG0837	glucose binding
B9J09_07540	COG1028	Short-chain dehydrogenase reductase Sdr
B9J09_07545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B9J09_07550	COG4191	Histidine kinase
B9J09_07555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9J09_07560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B9J09_07565	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B9J09_07575	COG1674	ftsk spoiiie
B9J09_07580	COG0492	ferredoxin-NADP+ reductase activity
B9J09_07590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B9J09_07595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B9J09_07605	COG0542	response to heat
B9J09_07610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B9J09_07625	COG2915	High frequency lysogenization protein hflD homolog
B9J09_07635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9J09_07655	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B9J09_07670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9J09_07675	COG4974	Belongs to the 'phage' integrase family
B9J09_07680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9J09_07720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B9J09_07725	COG0271	Belongs to the BolA IbaG family
B9J09_07735	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B9J09_07750	COG1137	ATPase activity
B9J09_07770	COG1660	Displays ATPase and GTPase activities
B9J09_07785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9J09_07805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9J09_07810	COG0629	single-stranded DNA binding
B9J09_07815	COG0142	geranyltranstransferase activity
B9J09_07820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B9J09_07825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9J09_07830	COG1845	cytochrome c oxidase, subunit III
B9J09_07835	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B9J09_07840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9J09_07840	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9J09_07855	COG1643	Atp-dependent helicase
B9J09_07860	COG0783	Belongs to the Dps family
B9J09_07865	COG0514	ATP-dependent DNA helicase (RecQ)
B9J09_07875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9J09_07885	COG0159	tryptophan synthase activity
B9J09_07890	COG0133	tryptophan synthase activity
B9J09_07895	COG0135	phosphoribosylanthranilate isomerase activity
B9J09_07910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B9J09_07920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B9J09_07925	COG2890	protein-(glutamine-N5) methyltransferase activity
B9J09_07930	COG1999	signal sequence binding
B9J09_07945	COG0741	lytic transglycosylase activity
B9J09_07950	COG0617	tRNA 3'-terminal CCA addition
B9J09_07955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9J09_07970	COG0156	8-amino-7-oxononanoate synthase activity
B9J09_07975	COG2267	carboxylic ester hydrolase activity
B9J09_07985	COG1846	Transcriptional regulator
B9J09_07995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9J09_08005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B9J09_08010	COG4208	sulfate ABC transporter
B9J09_08015	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B9J09_08030	COG3142	Participates in the control of copper homeostasis
B9J09_08040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B9J09_08045	COG0259	pyridoxamine-phosphate oxidase activity
B9J09_08055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B9J09_08060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B9J09_08070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B9J09_08085	COG2353	YceI-like domain
B9J09_08100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B9J09_08125	COG2894	cell division
B9J09_08145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9J09_08150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B9J09_08155	COG0772	Belongs to the SEDS family
B9J09_08160	COG0768	penicillin binding
B9J09_08165	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B9J09_08170	COG1792	Involved in formation and maintenance of cell shape
B9J09_08175	COG1077	Cell shape determining protein MreB Mrl
B9J09_08220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B9J09_08225	COG1127	ABC transporter
B9J09_08230	COG3218	ABC-type transport auxiliary lipoprotein component
B9J09_08230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B9J09_08245	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B9J09_08245	COG0644	oxidoreductase
B9J09_08255	COG2840	Smr protein MutS2
B9J09_08260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B9J09_08265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B9J09_08270	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B9J09_08275	COG0148	phosphopyruvate hydratase activity
B9J09_08280	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B9J09_08310	COG1253	flavin adenine dinucleotide binding
B9J09_08315	COG2733	membrane
B9J09_08340	COG0321	lipoyl(octanoyl) transferase activity
B9J09_08345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B9J09_08380	COG0668	transmembrane transport
B9J09_08385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B9J09_08405	COG2373	Large extracellular alpha-helical protein
B9J09_08560	COG0582	viral genome integration into host DNA
B9J09_08570	COG2911	Protein conserved in bacteria
B9J09_08575	COG0729	surface antigen
B9J09_08580	COG1956	GAF domain-containing protein
B9J09_08585	COG1643	Atp-dependent helicase
B9J09_08610	COG1131	(ABC) transporter
B9J09_08615	COG0842	Transport permease protein
B9J09_08660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9J09_08665	COG0039	L-malate dehydrogenase activity
B9J09_08670	COG0625	glutathione transferase activity
B9J09_08675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9J09_08715	COG1187	pseudouridine synthase activity
B9J09_08730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9J09_08735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9J09_08770	COG0776	regulation of translation
B9J09_08780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B9J09_08785	COG0740	serine-type endopeptidase activity
B9J09_08790	COG0544	peptidyl-prolyl cis-trans isomerase activity
B9J09_08805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B9J09_08825	COG0606	chelatase, subunit chli
B9J09_08830	COG2960	long-chain fatty acid transporting porin activity
B9J09_08835	COG0203	ribosomal protein L17
B9J09_08845	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B9J09_08850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B9J09_08855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B9J09_08860	COG0201	protein transport
B9J09_08865	COG0200	Binds to the 23S rRNA
B9J09_08870	COG1841	ribosomal large subunit assembly
B9J09_08875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B9J09_08880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B9J09_08885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B9J09_08890	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B9J09_08895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B9J09_08900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B9J09_08905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B9J09_08910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B9J09_08915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B9J09_08920	COG0255	Belongs to the universal ribosomal protein uL29 family
B9J09_08930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B9J09_08935	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B9J09_08940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B9J09_08945	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B9J09_08950	COG0089	rRNA binding
B9J09_08955	COG0088	Forms part of the polypeptide exit tunnel
B9J09_08960	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B9J09_08975	COG0356	it plays a direct role in the translocation of protons across the membrane
B9J09_08985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B9J09_08990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B9J09_08995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B9J09_09000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B9J09_09005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B9J09_09010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B9J09_09020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B9J09_09035	COG1064	alcohol dehydrogenase
B9J09_09050	COG0583	DNA-binding transcription factor activity
B9J09_09055	COG0312	modulator of DNA gyrase
B9J09_09060	COG3028	Belongs to the UPF0307 family
B9J09_09065	COG0312	modulator of DNA gyrase
B9J09_09075	COG1530	ribonuclease E activity
B9J09_09080	COG0424	maF-like protein
B9J09_09095	COG0494	nUDIX hydrolase
B9J09_09105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B9J09_09115	COG0019	diaminopimelate decarboxylase activity
B9J09_09120	COG1024	Enoyl-CoA hydratase
B9J09_09135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B9J09_09140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B9J09_09145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B9J09_09155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9J09_09160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B9J09_09165	COG0505	Belongs to the CarA family
B9J09_09170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B9J09_09225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9J09_09245	COG1663	tetraacyldisaccharide 4'-kinase activity
B9J09_09250	COG1132	(ABC) transporter
B9J09_09260	COG0811	peptide transport
B9J09_09270	COG1136	(ABC) transporter
B9J09_09275	COG4591	ABC-type transport system involved in lipoprotein release permease component
B9J09_09290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9J09_09300	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B9J09_09305	COG2009	succinate dehydrogenase
B9J09_09315	COG0354	folic acid binding
B9J09_09320	COG3842	ATPase activity
B9J09_09325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B9J09_09330	COG0837	glucose binding
B9J09_09335	COG0363	glucosamine-6-phosphate deaminase activity
B9J09_09370	COG0528	UMP kinase activity
B9J09_09395	COG2067	long-chain fatty acid transport protein
B9J09_09400	COG0233	cytoplasmic translational termination
B9J09_09405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B9J09_09410	COG0575	Belongs to the CDS family
B9J09_09420	COG0750	zinc metalloprotease
B9J09_09430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9J09_09435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9J09_09440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9J09_09445	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9J09_09450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B9J09_09460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B9J09_09480	COG2937	Belongs to the GPAT DAPAT family
B9J09_09510	COG1946	Acyl-CoA thioesterase
B9J09_09520	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B9J09_09530	COG1914	H( )-stimulated, divalent metal cation uptake system
B9J09_09535	COG1321	iron dependent repressor
B9J09_09540	COG0590	tRNA wobble adenosine to inosine editing
B9J09_09575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B9J09_09580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B9J09_09585	COG0165	Argininosuccinate lyase
B9J09_09595	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B9J09_09600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9J09_09605	COG0137	argininosuccinate synthase activity
B9J09_09610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B9J09_09625	COG0215	cysteine-tRNA ligase activity
B9J09_09630	COG2166	iron-sulfur cluster assembly
B9J09_09645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B9J09_09650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B9J09_09655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9J09_09665	COG3706	GGDEF domain
B9J09_09675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9J09_09690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B9J09_09695	COG0742	ribosomal rna small subunit methyltransferase
B9J09_09700	COG0326	Molecular chaperone. Has ATPase activity
B9J09_09705	COG0281	malic enzyme
B9J09_09705	COG0280	phosphate acetyltransferase
B9J09_09710	COG1301	dicarboxylic acid transport
B9J09_09760	COG0556	nucleotide-excision repair
B9J09_09785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B9J09_09810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B9J09_09815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9J09_09835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9J09_09835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9J09_09855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B9J09_09860	COG0488	(ABC) transporter
B9J09_09870	COG3011	Protein conserved in bacteria
B9J09_09880	COG0564	pseudouridine synthase activity
B9J09_09885	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9J09_09895	COG1918	ferrous iron import across plasma membrane
B9J09_09895	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B9J09_09905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B9J09_09915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B9J09_09930	COG0758	DNA mediated transformation
B9J09_09935	COG2922	Belongs to the Smg family
B9J09_09945	COG1754	DNA topoisomerase type I activity
B9J09_09945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B9J09_09950	COG0009	L-threonylcarbamoyladenylate synthase
B9J09_09980	COG2969	positive regulation of protein catabolic process
B9J09_09985	COG0625	glutathione transferase activity
B9J09_09990	COG2857	Cytochrome c1
B9J09_09995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B9J09_10000	COG0723	plastoquinol--plastocyanin reductase activity
B9J09_10005	COG0741	lytic transglycosylase activity
B9J09_10010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9J09_10015	COG1702	phosphate starvation-inducible protein PhoH
B9J09_10020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B9J09_10030	COG4535	Mg2 and Co2 transporter CorC
B9J09_10095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9J09_10105	COG1199	ATP-dependent helicase activity
B9J09_10115	COG0288	reversible hydration of carbon dioxide
B9J09_10140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B9J09_10145	COG2011	ABC-type metal ion transport system permease component
B9J09_10165	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9J09_10170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9J09_10185	COG0626	cystathionine gamma-synthase activity
B9J09_10190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B9J09_10195	COG0739	heme binding
B9J09_10210	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B9J09_10215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9J09_10220	COG1238	metal cluster binding
B9J09_10235	COG5002	protein histidine kinase activity
B9J09_10245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B9J09_10250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9J09_10255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9J09_10260	COG3858	chitin binding
B9J09_10260	COG1388	LysM domain
B9J09_10265	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B9J09_10275	COG1472	Belongs to the glycosyl hydrolase 3 family
B9J09_10290	COG3537	Alpha-1,2-mannosidase
B9J09_10300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B9J09_10305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9J09_10310	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B9J09_10320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9J09_10325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9J09_10365	COG3588	fructose-bisphosphate aldolase
B9J09_10375	COG0469	pyruvate kinase activity
B9J09_10385	COG0126	phosphoglycerate kinase activity
B9J09_10390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B9J09_10395	COG0735	belongs to the Fur family
B9J09_10405	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9J09_10405	COG5297	Belongs to the glycosyl hydrolase family 6
B9J09_10415	COG0612	Peptidase, M16
B9J09_10430	COG4305	rare lipoprotein A
B9J09_10435	COG0653	protein targeting
B9J09_10440	COG0739	heme binding
B9J09_10450	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B9J09_10460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B9J09_10470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B9J09_10475	COG1181	Belongs to the D-alanine--D-alanine ligase family
B9J09_10480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9J09_10485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B9J09_10495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9J09_10500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B9J09_10505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B9J09_10515	COG3116	cell division
B9J09_10520	COG0275	rRNA processing
B9J09_10540	COG3273	potassium ion transport
B9J09_10540	COG0471	metal ion transport
B9J09_10545	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B9J09_10580	COG2755	lipolytic protein G-D-S-L family
B9J09_10580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B9J09_10610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9J09_10640	COG0640	Transcriptional regulator
B9J09_10645	COG2391	methyltransferase activity
B9J09_10650	COG2391	methyltransferase activity
B9J09_10655	COG0730	response to heat
B9J09_10660	COG0717	Belongs to the dCTP deaminase family
B9J09_10670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B9J09_10675	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9J09_10680	COG0802	atpase or kinase
B9J09_10685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B9J09_10685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B9J09_10720	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
B9J09_10740	COG0776	regulation of translation
B9J09_10745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9J09_10745	COG0072	phenylalanine-tRNA ligase activity
B9J09_10750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B9J09_10755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B9J09_10765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B9J09_10770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B9J09_10795	COG0745	RESPONSE REGULATOR receiver
B9J09_10800	COG0642	Histidine kinase
B9J09_10805	COG0237	dephospho-CoA kinase activity
B9J09_10810	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B9J09_10860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9J09_10870	COG2831	hemolysin activation secretion protein
B9J09_10895	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
B9J09_10905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B9J09_10915	COG3115	cell septum assembly
B9J09_10925	COG0359	binds to the 23S rRNA
B9J09_10930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B9J09_10940	COG0316	Belongs to the HesB IscA family
B9J09_10945	COG0017	Asparaginyl-tRNA synthetase
B9J09_10975	COG0167	dihydroorotate dehydrogenase activity
B9J09_10980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B9J09_10985	COG0697	spore germination
B9J09_10995	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B9J09_11005	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B9J09_11010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B9J09_11025	COG1132	(ABC) transporter
B9J09_11035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9J09_11040	COG1538	Outer membrane efflux protein
B9J09_11045	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9J09_11060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B9J09_11075	COG4783	chaperone-mediated protein folding
B9J09_11085	COG0473	3-isopropylmalate dehydrogenase activity
B9J09_11095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B9J09_11105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B9J09_11115	COG0316	Belongs to the HesB IscA family
B9J09_11115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B9J09_11120	COG2154	pterin-4-alpha-carbinolamine dehydratase
B9J09_11130	COG0564	pseudouridine synthase activity
B9J09_11135	COG1530	ribonuclease E activity
B9J09_11140	COG2197	response regulator
B9J09_11185	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B9J09_11190	COG1278	Cold shock
B9J09_11200	COG0501	Belongs to the peptidase M48B family
B9J09_11210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B9J09_11215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B9J09_11220	COG0049	tRNA binding
B9J09_11225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B9J09_11230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B9J09_11235	COG0085	RNA polymerase activity
B9J09_11240	COG0222	ribosome binding
B9J09_11245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B9J09_11250	COG0081	regulation of translation
B9J09_11255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B9J09_11260	COG0250	Participates in transcription elongation, termination and antitermination
B9J09_11265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B9J09_11275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B9J09_11295	COG0012	GTP binding
B9J09_11300	COG0193	aminoacyl-tRNA hydrolase activity
B9J09_11305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B9J09_11310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B9J09_11320	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B9J09_11325	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B9J09_11335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B9J09_11340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B9J09_11350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B9J09_11350	COG0116	Belongs to the methyltransferase superfamily
B9J09_11400	COG2095	MarC family integral membrane protein
B9J09_11410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B9J09_11425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B9J09_11440	COG2132	Multicopper oxidase
B9J09_11450	COG0210	DNA helicase
B9J09_11455	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
B9J09_11460	COG0616	signal peptide processing
B9J09_11465	COG0534	Mate efflux family protein
B9J09_11485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B9J09_11495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B9J09_11500	COG2201	protein-glutamate methylesterase activity
B9J09_11505	COG2177	Part of the ABC transporter FtsEX involved in
B9J09_11510	COG2884	Cell division ATP-binding protein ftsE
B9J09_11515	COG0513	Belongs to the DEAD box helicase family
B9J09_11520	COG3118	belongs to the thioredoxin family
B9J09_11525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B9J09_11540	COG0793	Belongs to the peptidase S41A family
B9J09_11545	COG4942	peptidase
B9J09_11560	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9J09_11565	COG0493	'glutamate synthase
B9J09_11570	COG0070	glutamate synthase
B9J09_11570	COG0067	glutamate synthase
B9J09_11570	COG0069	glutamate synthase activity
B9J09_11605	COG1028	Short-chain dehydrogenase reductase Sdr
B9J09_11625	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B9J09_11670	COG1280	lysine exporter protein (LysE YggA)
B9J09_11680	COG4942	peptidase
B9J09_11710	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B9J09_11720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B9J09_11815	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9J09_11820	COG3657	addiction module killer protein
B9J09_11885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B9J09_11895	COG0706	membrane insertase activity
B9J09_11900	COG0594	ribonuclease P activity
B9J09_11990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B9J09_12000	COG3609	addiction module antidote protein, CC2985 family
B9J09_12005	COG3657	addiction module killer protein
B9J09_12065	COG3451	type IV secretory pathway VirB4
B9J09_12080	COG4962	Type ii secretion system protein e
B9J09_12090	COG0629	single-stranded DNA binding