locus-tag	class	description
D934_00005	COG1538	Outer membrane efflux protein
D934_00035	COG0745	RESPONSE REGULATOR receiver
D934_00040	COG4783	chaperone-mediated protein folding
D934_00050	COG0473	3-isopropylmalate dehydrogenase activity
D934_00065	COG3083	sulfuric ester hydrolase activity
D934_00070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D934_00095	COG0564	pseudouridine synthase activity
D934_00100	COG1530	ribonuclease E activity
D934_00105	COG2197	response regulator
D934_00150	COG1278	Cold shock
D934_00180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D934_00255	COG0012	GTP binding
D934_00270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D934_00360	COG2095	MarC family integral membrane protein
D934_00365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D934_00395	COG2132	Multicopper oxidase
D934_00405	COG0210	DNA helicase
D934_00415	COG0616	signal peptide processing
D934_00435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D934_00450	COG2201	protein-glutamate methylesterase activity
D934_00455	COG2177	Part of the ABC transporter FtsEX involved in
D934_00460	COG2884	Cell division ATP-binding protein ftsE
D934_00470	COG3118	belongs to the thioredoxin family
D934_00475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D934_00485	COG0793	Belongs to the peptidase S41A family
D934_00490	COG4942	peptidase
D934_00505	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D934_00515	COG0493	'glutamate synthase
D934_00520	COG0070	glutamate synthase
D934_00520	COG0069	glutamate synthase activity
D934_00520	COG0067	glutamate synthase
D934_00570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D934_00640	COG4942	peptidase
D934_00935	COG0187	DNA topoisomerase II activity
D934_00945	COG0501	Belongs to the peptidase M48B family
D934_00985	COG0408	coproporphyrinogen oxidase activity
D934_01010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D934_01080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D934_01090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D934_01105	COG0511	ligase activity, forming carbon-carbon bonds
D934_01110	COG0439	Biotin carboxylase
D934_01115	COG0210	DNA helicase
D934_01155	COG1040	competence protein
D934_01165	COG1752	Esterase of the alpha-beta hydrolase superfamily
D934_01215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D934_01225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D934_01255	COG3121	Chaperone
D934_01260	COG3539	Fimbrial protein
D934_01270	COG1546	Belongs to the CinA family
D934_01275	COG0477	Major facilitator Superfamily
D934_01280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D934_01295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D934_01305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D934_01315	COG1534	Rna-binding protein
D934_01345	COG1560	Kdo2-lipid A biosynthetic process
D934_01350	COG1519	Transferase
D934_01365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D934_01380	COG0024	Methionine aminopeptidase
D934_01395	COG1393	Belongs to the ArsC family
D934_01410	COG0367	asparagine synthase
D934_01420	COG2070	2-Nitropropane dioxygenase
D934_01440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D934_01455	COG0339	signal peptide processing
D934_01470	COG2132	Multicopper oxidase
D934_01570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D934_01580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D934_01635	COG2223	nitrite transmembrane transporter activity
D934_01645	COG0739	heme binding
D934_01680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D934_01695	COG1028	Short-chain dehydrogenase reductase Sdr
D934_01705	COG1272	protein, Hemolysin III
D934_01710	COG0463	Glycosyl transferase, family 2
D934_01715	COG0084	hydrolase, TatD family'
D934_01755	COG0330	HflC and HflK could
D934_01760	COG3956	TIGRFAM MazG family protein
D934_01765	COG1218	3'(2'),5'-bisphosphate nucleotidase
D934_01770	COG0494	nUDIX hydrolase
D934_01780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D934_01785	COG0513	Belongs to the DEAD box helicase family
D934_01790	COG0720	synthase
D934_01855	COG0512	Glutamine amidotransferase of anthranilate synthase
D934_01885	COG0006	proline dipeptidase activity
D934_01905	COG1862	Preprotein translocase
D934_01910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D934_01915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D934_01925	COG0617	tRNA 3'-terminal CCA addition
D934_01935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D934_01965	COG0195	Participates in both transcription termination and antitermination
D934_01995	COG1733	regulation of RNA biosynthetic process
D934_02050	COG2086	electron transfer activity
D934_02080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D934_02115	COG0477	Major facilitator Superfamily
D934_02140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D934_02145	COG0671	phosphoesterase, PA-phosphatase related
D934_02160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D934_02165	COG0628	permease
D934_02185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D934_02190	COG1090	epimerase
D934_02195	COG0318	PFAM AMP-dependent synthetase and ligase
D934_02220	COG1049	propionate catabolic process, 2-methylcitrate cycle
D934_02270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D934_02300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D934_02310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D934_02320	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
D934_02325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D934_02330	COG1034	ATP synthesis coupled electron transport
D934_02340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D934_02365	COG1007	ATP synthesis coupled electron transport
D934_02370	COG1028	Short-chain dehydrogenase reductase Sdr
D934_02375	COG2851	Citrate transporter
D934_02390	COG0642	Histidine kinase
D934_02410	COG0784	Response regulator, receiver
D934_02410	COG2205	protein histidine kinase activity
D934_02425	COG0281	malic enzyme
D934_02425	COG0280	phosphate acetyltransferase
D934_02435	COG0742	ribosomal rna small subunit methyltransferase
D934_02450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D934_02465	COG3706	GGDEF domain
D934_02475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D934_02485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D934_02500	COG2166	iron-sulfur cluster assembly
D934_02530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D934_02600	COG0590	tRNA wobble adenosine to inosine editing
D934_02605	COG1321	iron dependent repressor
D934_02610	COG1914	H( )-stimulated, divalent metal cation uptake system
D934_02630	COG1946	Acyl-CoA thioesterase
D934_02705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D934_02730	COG0575	Belongs to the CDS family
D934_02735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D934_02765	COG0528	UMP kinase activity
D934_02790	COG0800	Aldolase
D934_02810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D934_02820	COG0354	folic acid binding
D934_02830	COG2009	succinate dehydrogenase
D934_02835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D934_02845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D934_02870	COG2333	competence protein COMEC
D934_02870	COG0658	competence protein
D934_02875	COG0811	peptide transport
D934_02950	COG3077	Addiction module antitoxin, RelB DinJ family
D934_02955	COG3041	Addiction module toxin RelE StbE family
D934_03035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D934_03090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D934_03090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D934_03115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D934_03125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D934_03130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D934_03150	COG1024	Enoyl-CoA hydratase
D934_03155	COG0527	aspartate kinase activity
D934_03180	COG0494	nUDIX hydrolase
D934_03185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D934_03195	COG0424	maF-like protein
D934_03200	COG1530	ribonuclease E activity
D934_03215	COG0312	modulator of DNA gyrase
D934_03230	COG0312	modulator of DNA gyrase
D934_03235	COG0583	DNA-binding transcription factor activity
D934_03250	COG1064	alcohol dehydrogenase
D934_03310	COG0356	it plays a direct role in the translocation of protons across the membrane
D934_03325	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D934_03415	COG0201	protein transport
D934_03445	COG2960	long-chain fatty acid transporting porin activity
D934_03450	COG0606	chelatase, subunit chli
D934_03475	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D934_03500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D934_03510	COG0776	regulation of translation
D934_03540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D934_03545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D934_03560	COG1187	pseudouridine synthase activity
D934_03595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D934_03605	COG0625	glutathione transferase activity
D934_03615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D934_03655	COG0842	Transport permease protein
D934_03660	COG1131	(ABC) transporter
D934_03685	COG1643	Atp-dependent helicase
D934_03695	COG1956	GAF domain-containing protein
D934_03700	COG0729	surface antigen
D934_03705	COG2911	Protein conserved in bacteria
D934_03820	COG0668	transmembrane transport
D934_03860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D934_03890	COG2733	membrane
D934_03895	COG1253	flavin adenine dinucleotide binding
D934_03955	COG2840	Smr protein MutS2
D934_03970	COG0644	oxidoreductase
D934_03970	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D934_03985	COG3218	ABC-type transport auxiliary lipoprotein component
D934_03985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D934_03990	COG1127	ABC transporter
D934_03995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D934_04020	COG1077	Cell shape determining protein MreB Mrl
D934_04025	COG1792	Involved in formation and maintenance of cell shape
D934_04030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D934_04035	COG0768	penicillin binding
D934_04040	COG0772	Belongs to the SEDS family
D934_04050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D934_04070	COG2894	cell division
D934_04105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D934_04120	COG2353	YceI-like domain
D934_04200	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D934_04205	COG4208	sulfate ABC transporter
D934_04235	COG1846	Transcriptional regulator
D934_04270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D934_04280	COG0741	lytic transglycosylase activity
D934_04310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D934_04350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D934_04360	COG0514	ATP-dependent DNA helicase (RecQ)
D934_04365	COG0783	Belongs to the Dps family
D934_04370	COG1643	Atp-dependent helicase
D934_04490	COG3772	lysozyme
D934_04605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D934_04610	COG1845	cytochrome c oxidase, subunit III
D934_04615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D934_04620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D934_04625	COG0142	geranyltranstransferase activity
D934_04640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D934_04660	COG2239	Acts as a magnesium transporter
D934_04670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D934_04705	COG1137	ATPase activity
D934_04720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D934_04730	COG0271	Belongs to the BolA IbaG family
D934_04770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D934_04780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D934_04785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D934_04820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D934_04855	COG0542	response to heat
D934_04875	COG0492	ferredoxin-NADP+ reductase activity
D934_04895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D934_04910	COG4191	Histidine kinase
D934_04915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D934_04920	COG1028	Short-chain dehydrogenase reductase Sdr
D934_04950	COG1609	Transcriptional regulator
D934_04955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D934_04960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D934_04965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D934_04975	COG0726	polysaccharide deacetylase
D934_04980	COG0297	glycogen (starch) synthase activity
D934_04995	COG0719	Fe-S assembly protein
D934_05000	COG0396	ATPase activity
D934_05005	COG0719	Fe-S assembly protein
D934_05010	COG1959	2 iron, 2 sulfur cluster binding
D934_05195	COG3772	lysozyme
D934_05235	COG4197	protein conserved in bacteria, prophage-related
D934_05315	COG3617	BRO family, N-terminal domain
D934_05385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D934_05390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D934_05395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D934_05400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D934_05415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D934_05440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D934_05440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D934_05460	COG0488	(ABC) transporter
D934_05500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D934_05500	COG1918	ferrous iron import across plasma membrane
D934_05510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D934_05535	COG0758	DNA mediated transformation
D934_05585	COG2969	positive regulation of protein catabolic process
D934_05590	COG0625	glutathione transferase activity
D934_05595	COG2857	Cytochrome c1
D934_05600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D934_05610	COG0741	lytic transglycosylase activity
D934_05625	COG1702	phosphate starvation-inducible protein PhoH
D934_05640	COG4535	Mg2 and Co2 transporter CorC
D934_05650	COG0598	Magnesium transport protein CorA
D934_05785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D934_05790	COG0277	FAD linked oxidase domain protein
D934_05795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D934_05800	COG0531	amino acid
D934_05805	COG0531	amino acid
D934_05855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D934_05890	COG0460	homoserine dehydrogenase
D934_05890	COG0527	aspartate kinase activity
D934_05910	COG1686	Belongs to the peptidase S11 family
D934_05940	COG4953	penicillin-binding protein 1C
D934_05965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D934_05985	COG0571	ribonuclease III activity
D934_06040	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D934_06045	COG1506	peptidase
D934_06045	COG0823	Involved in the tonB-independent uptake of proteins
D934_06050	COG1297	OPT oligopeptide transporter protein
D934_06090	COG0676	glucose-6-phosphate 1-epimerase activity
D934_06100	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D934_06105	COG1335	isochorismatase
D934_06110	COG0318	PFAM AMP-dependent synthetase and ligase
D934_06120	COG0463	Glycosyl transferase, family 2
D934_06135	COG1192	Involved in chromosome partitioning
D934_06290	COG3617	BRO family, N-terminal domain
D934_06305	COG3772	lysozyme
D934_06375	COG3093	addiction module antidote protein HigA
D934_06455	COG0629	single-stranded DNA binding
D934_06485	COG5532	Uncharacterized conserved protein (DUF2303)
D934_06550	COG4197	protein conserved in bacteria, prophage-related
D934_06570	COG3617	BRO family, N-terminal domain
D934_06575	COG3617	BRO family, N-terminal domain
D934_06590	COG0305	Participates in initiation and elongation during chromosome replication
D934_06605	COG3772	lysozyme
D934_06630	COG5410	chromosome segregation
D934_06635	COG3567	Phage-associated protein, HI1409 family
D934_06650	COG2369	cell adhesion
D934_06750	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_06755	COG3657	addiction module killer protein
D934_06785	COG1131	(ABC) transporter
D934_06790	COG0386	Belongs to the glutathione peroxidase family
D934_06825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D934_06835	COG2027	D-alanyl-D-alanine carboxypeptidase
D934_06840	COG2027	D-alanyl-D-alanine carboxypeptidase
D934_06860	COG2226	methyltransferase
D934_06880	COG0400	carboxylic ester hydrolase activity
D934_06885	COG3275	phosphorelay sensor kinase activity
D934_06940	COG0463	Glycosyl transferase, family 2
D934_06950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D934_06965	COG0392	lysyltransferase activity
D934_06965	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D934_06970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D934_07005	COG3617	BRO family, N-terminal domain
D934_07090	COG3772	lysozyme
D934_07185	COG0251	oxidation-reduction process
D934_07200	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D934_07215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D934_07230	COG4969	Belongs to the N-Me-Phe pilin family
D934_07270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D934_07300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D934_07355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D934_07370	COG0537	adenosine 5'-monophosphoramidase activity
D934_07390	COG0714	Associated with various cellular activities
D934_07405	COG1399	metal-binding, possibly nucleic acid-binding protein
D934_07410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D934_07415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D934_07450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D934_07455	COG1764	response to oxidative stress
D934_07460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D934_07520	COG2353	YceI-like domain
D934_07535	COG0347	Belongs to the P(II) protein family
D934_07560	COG2204	response regulator
D934_07565	COG3852	Histidine kinase
D934_07585	COG1943	Transposase
D934_07600	COG0675	Transposase, IS605 OrfB family
D934_07655	COG0629	single-stranded DNA binding
D934_07670	COG4969	Belongs to the N-Me-Phe pilin family
D934_07755	COG0358	DNA primase activity
D934_07780	COG0740	serine-type endopeptidase activity
D934_07795	COG3772	lysozyme
D934_07845	COG5449	Phage conserved hypothetical protein BR0599
D934_07930	COG0745	RESPONSE REGULATOR receiver
D934_07935	COG2205	protein histidine kinase activity
D934_07970	COG2193	ferroxidase activity
D934_08000	COG0861	Integral membrane protein TerC family
D934_08005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D934_08015	COG0531	amino acid
D934_08030	COG1116	anion transmembrane transporter activity
D934_08045	COG2853	Lipoprotein
D934_08065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D934_08070	COG1127	ABC transporter
D934_08075	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D934_08080	COG1074	ATP-dependent DNA helicase activity
D934_08100	COG0180	Tryptophanyl-tRNA synthetase
D934_08130	COG0358	DNA primase activity
D934_08140	COG1610	YqeY-like protein
D934_08160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D934_08165	COG0668	transmembrane transport
D934_08185	COG1183	phosphatidylcholine synthase activity
D934_08215	COG0604	alcohol dehydrogenase
D934_08220	COG0330	HflC and HflK could
D934_08225	COG0330	HflC and HflK could
D934_08240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D934_08270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D934_08285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D934_08295	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D934_08305	COG1611	Belongs to the LOG family
D934_08355	COG0629	single-stranded DNA binding
D934_08385	COG5532	Uncharacterized conserved protein (DUF2303)
D934_08460	COG3617	BRO family, N-terminal domain
D934_08475	COG0305	Participates in initiation and elongation during chromosome replication
D934_08495	COG3772	lysozyme
D934_08520	COG5410	chromosome segregation
D934_08525	COG3567	Phage-associated protein, HI1409 family
D934_08540	COG2369	cell adhesion
D934_08640	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_08645	COG3657	addiction module killer protein
D934_08700	COG4206	TonB-dependent receptor
D934_08705	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D934_08725	COG0277	FAD linked oxidase domain protein
D934_08730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D934_08740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D934_08760	COG0305	Participates in initiation and elongation during chromosome replication
D934_08780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D934_08785	COG0667	Aldo Keto reductase
D934_08825	COG2194	sulfuric ester hydrolase activity
D934_08835	COG0352	thiamine-phosphate diphosphorylase activity
D934_08875	COG0629	single-stranded DNA binding
D934_08890	COG4969	Belongs to the N-Me-Phe pilin family
D934_08975	COG0358	DNA primase activity
D934_09000	COG0740	serine-type endopeptidase activity
D934_09015	COG3772	lysozyme
D934_09065	COG5449	Phage conserved hypothetical protein BR0599
D934_09210	COG2337	Toxic component of a toxin-antitoxin (TA) module
D934_09390	COG0406	alpha-ribazole phosphatase activity
D934_09410	COG0386	Belongs to the glutathione peroxidase family
D934_09415	COG3104	oligopeptide transport
D934_09430	COG0602	queuosine metabolic process
D934_09440	COG2885	chlorophyll binding
D934_09465	COG0824	Thioesterase
D934_09505	COG0552	protein localization to endoplasmic reticulum
D934_09525	COG0084	hydrolase, TatD family'
D934_09540	COG0512	Glutamine amidotransferase of anthranilate synthase
D934_09540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D934_09570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D934_09630	COG2091	lysine biosynthetic process via aminoadipic acid
D934_09645	COG1301	dicarboxylic acid transport
D934_09680	COG0339	signal peptide processing
D934_09690	COG0285	dihydrofolate synthase activity
D934_09725	COG0840	transmembrane signaling receptor activity
D934_09785	COG0596	Alpha beta hydrolase
D934_09805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D934_09815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D934_09825	COG0138	bifunctional purine biosynthesis protein purh
D934_09840	COG1289	transmembrane transporter activity
D934_09845	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D934_09855	COG0302	gtp cyclohydrolase
D934_09860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D934_09870	COG0557	exoribonuclease II activity
D934_09880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D934_09885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D934_09925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D934_09960	COG0778	Nitroreductase
D934_09970	COG0006	proline dipeptidase activity
D934_09990	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D934_10010	COG0025	NhaP-type Na H and K H
D934_10025	COG2925	Exonuclease
D934_10085	COG1028	Short-chain dehydrogenase reductase Sdr
D934_10090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D934_10130	COG3451	type IV secretory pathway VirB4
D934_10150	COG4962	Type ii secretion system protein e
D934_10180	COG2902	Dehydrogenase
D934_10190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D934_10200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D934_10310	COG2850	peptidyl-arginine hydroxylation
D934_10315	COG0567	Dehydrogenase, E1 component
D934_10345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D934_10370	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D934_10395	COG0254	rRNA binding
D934_10405	COG0583	DNA-binding transcription factor activity
D934_10410	COG3634	alkyl hydroperoxide reductase activity
D934_10415	COG0450	alkyl hydroperoxide reductase
D934_10430	COG1450	Type ii and iii secretion system protein
D934_10445	COG3166	PFAM Fimbrial assembly family protein
D934_10450	COG3156	type II secretion system protein K
D934_10455	COG4795	General secretion pathway protein
D934_10460	COG2165	general secretion pathway protein
D934_10465	COG4970	Tfp pilus assembly protein FimT
D934_10470	COG2165	general secretion pathway protein
D934_10485	COG1459	type II secretion system
D934_10490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D934_10495	COG5295	Hep Hag repeat protein
D934_10535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D934_10550	COG1561	YicC-like family, N-terminal region
D934_10560	COG1758	RNA polymerase activity
D934_10575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D934_10630	COG0308	aminopeptidase N
D934_10675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D934_10715	COG3316	Transposase and inactivated derivatives
D934_10740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D934_10795	COG2267	carboxylic ester hydrolase activity
D934_10815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D934_10880	COG1605	Chorismate mutase
D934_10880	COG0077	Prephenate dehydratase
D934_10895	COG1668	transmembrane transport
D934_10900	COG4555	ABC transporter
D934_10925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D934_10935	COG1605	Chorismate mutase
D934_10935	COG0287	Prephenate dehydrogenase
D934_10940	COG0484	heat shock protein binding
D934_10970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D934_10995	COG1278	Cold shock
D934_11025	COG0745	RESPONSE REGULATOR receiver
D934_11030	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D934_11050	COG0438	transferase activity, transferring glycosyl groups
D934_11110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D934_11115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D934_11130	COG1064	alcohol dehydrogenase
D934_11155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D934_11165	COG0436	Aminotransferase
D934_11220	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
D934_11220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D934_11270	COG0196	riboflavin kinase activity
D934_11275	COG0728	peptidoglycan biosynthetic process
D934_11280	COG0268	Binds directly to 16S ribosomal RNA
D934_11300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D934_11335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D934_11350	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D934_11370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D934_11375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D934_11405	COG0395	ABC-type sugar transport system, permease component
D934_11410	COG1175	transmembrane transport
D934_11435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D934_11455	COG0436	Aminotransferase
D934_11515	COG5434	Belongs to the glycosyl hydrolase 28 family
D934_11535	COG0402	S-adenosylhomocysteine deaminase activity
D934_11545	COG1509	lysine 2,3-aminomutase activity
D934_11585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D934_11590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D934_11605	COG1028	Short-chain dehydrogenase reductase Sdr
D934_11655	COG0142	geranyltranstransferase activity
D934_11680	COG1301	dicarboxylic acid transport
D934_11690	COG0791	NLP P60 protein
D934_11695	COG0791	NLP P60 protein
D934_11705	COG2311	Membrane
D934_11725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D934_11785	COG0351	phosphomethylpyrimidine kinase
D934_11785	COG0352	thiamine-phosphate diphosphorylase activity
D934_11795	COG1324	tolerance protein
D934_11805	COG0459	protein refolding
D934_11835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D934_11840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D934_11855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D934_11875	COG4774	siderophore transport
D934_11900	COG1477	protein flavinylation
D934_11910	COG1555	photosystem II stabilization
D934_11920	COG3178	'Phosphotransferase
D934_11925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D934_11935	COG0628	permease
D934_11950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D934_11980	COG3590	peptidase
D934_12030	COG0805	protein transport
D934_12045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D934_12045	COG0519	Catalyzes the synthesis of GMP from XMP
D934_12060	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
D934_12080	COG3107	peptidoglycan biosynthetic process
D934_12100	COG2878	Part of a membrane complex involved in electron transport
D934_12165	COG0358	DNA primase activity
D934_12185	COG4197	protein conserved in bacteria, prophage-related
D934_12250	COG4969	Belongs to the N-Me-Phe pilin family
D934_12265	COG0629	single-stranded DNA binding
D934_12320	COG3657	addiction module killer protein
D934_12325	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_12375	COG3657	addiction module killer protein
D934_12380	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_12405	COG0675	Transposase, IS605 OrfB family
D934_12455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D934_12460	COG0488	(ABC) transporter
D934_12475	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D934_12485	COG4651	solute:proton antiporter activity
D934_12485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D934_12515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D934_12545	COG0859	PFAM glycosyl transferase family 9
D934_12560	COG0631	protein serine/threonine phosphatase activity
D934_12565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D934_12570	COG0328	RNA-DNA hybrid ribonuclease activity
D934_12585	COG2183	response to ionizing radiation
D934_12600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D934_12610	COG3118	belongs to the thioredoxin family
D934_12655	COG2951	lytic endotransglycosylase activity
D934_12795	COG3210	domain, Protein
D934_12820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D934_12830	COG1199	ATP-dependent helicase activity
D934_12845	COG0288	reversible hydration of carbon dioxide
D934_12865	COG2011	ABC-type metal ion transport system permease component
D934_12880	COG0508	dehydrogenase complex catalyzes the overall conversion of
D934_12885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D934_12900	COG0626	cystathionine gamma-synthase activity
D934_12905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D934_12910	COG0739	heme binding
D934_12930	COG1238	metal cluster binding
D934_12950	COG5002	protein histidine kinase activity
D934_12975	COG3858	chitin binding
D934_12975	COG1388	LysM domain
D934_12980	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D934_12990	COG1472	Belongs to the glycosyl hydrolase 3 family
D934_13005	COG3537	Alpha-1,2-mannosidase
D934_13030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D934_13035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D934_13075	COG0469	pyruvate kinase activity
D934_13090	COG0735	belongs to the Fur family
D934_13100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D934_13100	COG5297	Belongs to the glycosyl hydrolase family 6
D934_13110	COG0612	Peptidase, M16
D934_13125	COG4305	rare lipoprotein A
D934_13135	COG0739	heme binding
D934_13145	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D934_13150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D934_13160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D934_13190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D934_13205	COG3116	cell division
D934_13220	COG3273	potassium ion transport
D934_13220	COG0471	metal ion transport
D934_13270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D934_13335	COG0860	N-Acetylmuramoyl-L-alanine amidase
D934_13340	COG0802	atpase or kinase
D934_13345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D934_13345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D934_13420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D934_13445	COG0745	RESPONSE REGULATOR receiver
D934_13450	COG0642	Histidine kinase
D934_13460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D934_13510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D934_13520	COG2831	hemolysin activation secretion protein
D934_13550	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D934_13595	COG0316	Belongs to the HesB IscA family
D934_13635	COG0697	spore germination
D934_13640	COG0671	phosphoesterase, PA-phosphatase related
D934_13645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D934_13655	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D934_13675	COG1132	(ABC) transporter
D934_13690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D934_13750	COG0675	Transposase, IS605 OrfB family
D934_13755	COG3077	Addiction module antitoxin, RelB DinJ family
D934_13790	COG0675	Transposase, IS605 OrfB family
D934_13795	COG1943	Transposase
D934_13835	COG2027	D-alanyl-D-alanine carboxypeptidase
D934_13910	COG3736	Type IV secretory pathway, component VirB8