locus-tag	class	description
LZ756_00025	COG0187	DNA topoisomerase II activity
LZ756_00035	COG0501	Belongs to the peptidase M48B family
LZ756_00075	COG0408	coproporphyrinogen oxidase activity
LZ756_00095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZ756_00155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZ756_00165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZ756_00175	COG0511	ligase activity, forming carbon-carbon bonds
LZ756_00180	COG0439	Biotin carboxylase
LZ756_00185	COG0210	DNA helicase
LZ756_00220	COG1040	competence protein
LZ756_00230	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZ756_00270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ756_00280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZ756_00310	COG3121	Chaperone
LZ756_00315	COG3539	Fimbrial protein
LZ756_00320	COG1546	Belongs to the CinA family
LZ756_00325	COG0477	Major facilitator Superfamily
LZ756_00330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZ756_00345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZ756_00360	COG1534	Rna-binding protein
LZ756_00390	COG1560	Kdo2-lipid A biosynthetic process
LZ756_00395	COG1519	Transferase
LZ756_00410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LZ756_00435	COG1393	Belongs to the ArsC family
LZ756_00445	COG0367	asparagine synthase
LZ756_00455	COG2070	2-Nitropropane dioxygenase
LZ756_00470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LZ756_00485	COG0339	signal peptide processing
LZ756_00570	COG4221	oxidoreductase activity
LZ756_00590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZ756_00600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ756_00650	COG2223	nitrite transmembrane transporter activity
LZ756_00660	COG0739	heme binding
LZ756_00695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ756_00710	COG1028	Short-chain dehydrogenase reductase Sdr
LZ756_00720	COG1272	protein, Hemolysin III
LZ756_00725	COG0463	Glycosyl transferase, family 2
LZ756_00730	COG0084	hydrolase, TatD family'
LZ756_00760	COG0330	HflC and HflK could
LZ756_00765	COG3956	TIGRFAM MazG family protein
LZ756_00770	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZ756_00775	COG0494	nUDIX hydrolase
LZ756_00785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZ756_00790	COG0513	Belongs to the DEAD box helicase family
LZ756_00795	COG0720	synthase
LZ756_00820	COG1981	membrane
LZ756_00855	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ756_00885	COG0006	proline dipeptidase activity
LZ756_00905	COG1862	Preprotein translocase
LZ756_00910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ756_00915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ756_00925	COG0617	tRNA 3'-terminal CCA addition
LZ756_00935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LZ756_00965	COG0195	Participates in both transcription termination and antitermination
LZ756_00995	COG1733	regulation of RNA biosynthetic process
LZ756_01045	COG2086	electron transfer activity
LZ756_01075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ756_01100	COG0477	Major facilitator Superfamily
LZ756_01120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZ756_01125	COG0671	phosphoesterase, PA-phosphatase related
LZ756_01140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZ756_01145	COG0628	permease
LZ756_01165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ756_01170	COG1090	epimerase
LZ756_01175	COG0318	PFAM AMP-dependent synthetase and ligase
LZ756_01195	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZ756_01250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ756_01280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ756_01290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ756_01300	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZ756_01305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZ756_01310	COG1034	ATP synthesis coupled electron transport
LZ756_01345	COG1007	ATP synthesis coupled electron transport
LZ756_01350	COG1028	Short-chain dehydrogenase reductase Sdr
LZ756_01355	COG2851	Citrate transporter
LZ756_01370	COG0642	Histidine kinase
LZ756_01405	COG0280	phosphate acetyltransferase
LZ756_01405	COG0281	malic enzyme
LZ756_01415	COG0742	ribosomal rna small subunit methyltransferase
LZ756_01430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZ756_01450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZ756_01475	COG2166	iron-sulfur cluster assembly
LZ756_01500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZ756_01575	COG1321	iron dependent repressor
LZ756_01580	COG1914	H( )-stimulated, divalent metal cation uptake system
LZ756_01595	COG1946	Acyl-CoA thioesterase
LZ756_01660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ756_01685	COG0575	Belongs to the CDS family
LZ756_01690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LZ756_01720	COG0528	UMP kinase activity
LZ756_01740	COG0800	Aldolase
LZ756_01760	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZ756_01770	COG0354	folic acid binding
LZ756_01780	COG2009	succinate dehydrogenase
LZ756_01785	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZ756_01795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZ756_01820	COG2333	competence protein COMEC
LZ756_01820	COG0658	competence protein
LZ756_01825	COG0811	peptide transport
LZ756_01905	COG3077	Addiction module antitoxin, RelB DinJ family
LZ756_01910	COG3041	Addiction module toxin RelE StbE family
LZ756_01990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ756_02030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZ756_02030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZ756_02050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZ756_02060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZ756_02085	COG1024	Enoyl-CoA hydratase
LZ756_02090	COG0527	aspartate kinase activity
LZ756_02110	COG0494	nUDIX hydrolase
LZ756_02115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZ756_02125	COG0424	maF-like protein
LZ756_02140	COG0312	modulator of DNA gyrase
LZ756_02150	COG0312	modulator of DNA gyrase
LZ756_02155	COG0583	DNA-binding transcription factor activity
LZ756_02170	COG1064	alcohol dehydrogenase
LZ756_02230	COG0356	it plays a direct role in the translocation of protons across the membrane
LZ756_02250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LZ756_02350	COG0201	protein transport
LZ756_02380	COG2960	long-chain fatty acid transporting porin activity
LZ756_02385	COG0606	chelatase, subunit chli
LZ756_02410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZ756_02435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZ756_02470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ756_02475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ756_02520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ756_02525	COG0625	glutathione transferase activity
LZ756_02535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZ756_02540	COG1217	gtp-binding protein TYPA
LZ756_02580	COG0842	Transport permease protein
LZ756_02585	COG1131	(ABC) transporter
LZ756_02605	COG1643	Atp-dependent helicase
LZ756_02620	COG1956	GAF domain-containing protein
LZ756_02625	COG0729	surface antigen
LZ756_02630	COG2911	Protein conserved in bacteria
LZ756_02730	COG0668	transmembrane transport
LZ756_02760	COG5297	Belongs to the glycosyl hydrolase family 6
LZ756_02765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZ756_02795	COG2733	membrane
LZ756_02800	COG1253	flavin adenine dinucleotide binding
LZ756_02855	COG2840	Smr protein MutS2
LZ756_02865	COG0644	oxidoreductase
LZ756_02865	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZ756_02880	COG3218	ABC-type transport auxiliary lipoprotein component
LZ756_02880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZ756_02885	COG1127	ABC transporter
LZ756_02890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ756_02920	COG1077	Cell shape determining protein MreB Mrl
LZ756_02930	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZ756_02935	COG0768	penicillin binding
LZ756_02940	COG0772	Belongs to the SEDS family
LZ756_02950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ756_02970	COG2894	cell division
LZ756_03000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZ756_03015	COG2353	YceI-like domain
LZ756_03090	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZ756_03095	COG4208	sulfate ABC transporter
LZ756_03120	COG1846	Transcriptional regulator
LZ756_03150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZ756_03160	COG0741	lytic transglycosylase activity
LZ756_03190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZ756_03225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZ756_03235	COG0514	ATP-dependent DNA helicase (RecQ)
LZ756_03240	COG0783	Belongs to the Dps family
LZ756_03245	COG1643	Atp-dependent helicase
LZ756_03370	COG3772	lysozyme
LZ756_03470	COG0251	oxidation-reduction process
LZ756_03485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZ756_03500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZ756_03515	COG4969	Belongs to the N-Me-Phe pilin family
LZ756_03555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LZ756_03585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZ756_03630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LZ756_03645	COG0537	adenosine 5'-monophosphoramidase activity
LZ756_03665	COG0714	Associated with various cellular activities
LZ756_03675	COG1399	metal-binding, possibly nucleic acid-binding protein
LZ756_03680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LZ756_03685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ756_03720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ756_03725	COG1764	response to oxidative stress
LZ756_03730	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZ756_03790	COG2353	YceI-like domain
LZ756_03800	COG0174	glutamine synthetase
LZ756_03805	COG0347	Belongs to the P(II) protein family
LZ756_03820	COG2204	response regulator
LZ756_03825	COG3852	Histidine kinase
LZ756_03860	COG0675	Transposase, IS605 OrfB family
LZ756_03920	COG0629	single-stranded DNA binding
LZ756_03935	COG4969	Belongs to the N-Me-Phe pilin family
LZ756_04015	COG0358	DNA primase activity
LZ756_04040	COG0740	serine-type endopeptidase activity
LZ756_04060	COG3772	lysozyme
LZ756_04110	COG5449	Phage conserved hypothetical protein BR0599
LZ756_04225	COG2193	ferroxidase activity
LZ756_04255	COG0861	Integral membrane protein TerC family
LZ756_04260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZ756_04265	COG0531	amino acid
LZ756_04275	COG1116	anion transmembrane transporter activity
LZ756_04285	COG2853	Lipoprotein
LZ756_04305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ756_04310	COG1127	ABC transporter
LZ756_04315	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZ756_04320	COG1074	ATP-dependent DNA helicase activity
LZ756_04355	COG0358	DNA primase activity
LZ756_04365	COG1610	YqeY-like protein
LZ756_04380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZ756_04385	COG0668	transmembrane transport
LZ756_04405	COG1183	phosphatidylcholine synthase activity
LZ756_04435	COG0604	alcohol dehydrogenase
LZ756_04440	COG0330	HflC and HflK could
LZ756_04445	COG0330	HflC and HflK could
LZ756_04460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZ756_04490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ756_04500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZ756_04505	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZ756_04510	COG1611	Belongs to the LOG family
LZ756_04560	COG0629	single-stranded DNA binding
LZ756_04585	COG5532	Uncharacterized conserved protein (DUF2303)
LZ756_04675	COG3617	BRO family, N-terminal domain
LZ756_04690	COG0305	Participates in initiation and elongation during chromosome replication
LZ756_04715	COG3772	lysozyme
LZ756_04740	COG5410	chromosome segregation
LZ756_04745	COG3567	Phage-associated protein, HI1409 family
LZ756_04750	COG2369	cell adhesion
LZ756_04860	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ756_04865	COG3657	addiction module killer protein
LZ756_04895	COG1131	(ABC) transporter
LZ756_04900	COG0386	Belongs to the glutathione peroxidase family
LZ756_04930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ756_04940	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ756_04945	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ756_04965	COG2226	methyltransferase
LZ756_04985	COG0400	carboxylic ester hydrolase activity
LZ756_04990	COG3275	phosphorelay sensor kinase activity
LZ756_05040	COG0463	Glycosyl transferase, family 2
LZ756_05050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZ756_05060	COG0392	lysyltransferase activity
LZ756_05060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZ756_05065	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ756_05100	COG3617	BRO family, N-terminal domain
LZ756_05190	COG3772	lysozyme
LZ756_05305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZ756_05310	COG1845	cytochrome c oxidase, subunit III
LZ756_05315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZ756_05320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZ756_05325	COG0142	geranyltranstransferase activity
LZ756_05340	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZ756_05360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZ756_05395	COG1137	ATPase activity
LZ756_05410	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZ756_05455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ756_05465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZ756_05470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZ756_05495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ756_05525	COG0542	response to heat
LZ756_05545	COG0492	ferredoxin-NADP+ reductase activity
LZ756_05565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZ756_05575	COG4191	Histidine kinase
LZ756_05580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZ756_05585	COG1028	Short-chain dehydrogenase reductase Sdr
LZ756_05615	COG1609	Transcriptional regulator
LZ756_05620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZ756_05625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZ756_05630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZ756_05640	COG0726	polysaccharide deacetylase
LZ756_05645	COG0297	glycogen (starch) synthase activity
LZ756_05660	COG0719	Fe-S assembly protein
LZ756_05665	COG0396	ATPase activity
LZ756_05670	COG0719	Fe-S assembly protein
LZ756_05675	COG1959	2 iron, 2 sulfur cluster binding
LZ756_05875	COG3772	lysozyme
LZ756_05890	COG3617	BRO family, N-terminal domain
LZ756_06040	COG1192	Involved in chromosome partitioning
LZ756_06055	COG0463	Glycosyl transferase, family 2
LZ756_06065	COG0318	PFAM AMP-dependent synthetase and ligase
LZ756_06070	COG1335	isochorismatase
LZ756_06075	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZ756_06085	COG0676	glucose-6-phosphate 1-epimerase activity
LZ756_06115	COG1297	OPT oligopeptide transporter protein
LZ756_06120	COG0823	Involved in the tonB-independent uptake of proteins
LZ756_06120	COG1506	peptidase
LZ756_06125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ756_06170	COG0571	ribonuclease III activity
LZ756_06190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ756_06215	COG4953	penicillin-binding protein 1C
LZ756_06240	COG1686	Belongs to the peptidase S11 family
LZ756_06260	COG0527	aspartate kinase activity
LZ756_06260	COG0460	homoserine dehydrogenase
LZ756_06295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LZ756_06345	COG0531	amino acid
LZ756_06350	COG0531	amino acid
LZ756_06355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZ756_06360	COG0277	FAD linked oxidase domain protein
LZ756_06365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZ756_06455	COG0598	Magnesium transport protein CorA
LZ756_06465	COG4535	Mg2 and Co2 transporter CorC
LZ756_06480	COG1702	phosphate starvation-inducible protein PhoH
LZ756_06490	COG0741	lytic transglycosylase activity
LZ756_06500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZ756_06505	COG2857	Cytochrome c1
LZ756_06510	COG0625	glutathione transferase activity
LZ756_06515	COG2969	positive regulation of protein catabolic process
LZ756_06560	COG0758	DNA mediated transformation
LZ756_06585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZ756_06595	COG1918	ferrous iron import across plasma membrane
LZ756_06595	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LZ756_06635	COG0488	(ABC) transporter
LZ756_06655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ756_06655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ756_06680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZ756_06700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZ756_06770	COG3617	BRO family, N-terminal domain
LZ756_06850	COG4197	protein conserved in bacteria, prophage-related
LZ756_06895	COG3772	lysozyme
LZ756_06965	COG3093	addiction module antidote protein HigA
LZ756_07040	COG0629	single-stranded DNA binding
LZ756_07070	COG5532	Uncharacterized conserved protein (DUF2303)
LZ756_07155	COG3617	BRO family, N-terminal domain
LZ756_07160	COG3617	BRO family, N-terminal domain
LZ756_07175	COG0305	Participates in initiation and elongation during chromosome replication
LZ756_07190	COG3772	lysozyme
LZ756_07215	COG5410	chromosome segregation
LZ756_07220	COG3567	Phage-associated protein, HI1409 family
LZ756_07235	COG2369	cell adhesion
LZ756_07340	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ756_07345	COG3657	addiction module killer protein
LZ756_07395	COG0277	FAD linked oxidase domain protein
LZ756_07400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ756_07410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZ756_07435	COG0305	Participates in initiation and elongation during chromosome replication
LZ756_07445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ756_07450	COG0667	Aldo Keto reductase
LZ756_07490	COG2194	sulfuric ester hydrolase activity
LZ756_07500	COG0352	thiamine-phosphate diphosphorylase activity
LZ756_07540	COG0629	single-stranded DNA binding
LZ756_07555	COG4969	Belongs to the N-Me-Phe pilin family
LZ756_07640	COG0358	DNA primase activity
LZ756_07670	COG0740	serine-type endopeptidase activity
LZ756_07695	COG3772	lysozyme
LZ756_07745	COG5449	Phage conserved hypothetical protein BR0599
LZ756_07855	COG0582	viral genome integration into host DNA
LZ756_07890	COG2337	Toxic component of a toxin-antitoxin (TA) module
LZ756_07930	COG2337	Toxic component of a toxin-antitoxin (TA) module
LZ756_08000	COG0582	viral genome integration into host DNA
LZ756_08125	COG0406	alpha-ribazole phosphatase activity
LZ756_08145	COG0386	Belongs to the glutathione peroxidase family
LZ756_08165	COG0602	queuosine metabolic process
LZ756_08175	COG2885	chlorophyll binding
LZ756_08200	COG0824	Thioesterase
LZ756_08245	COG0552	protein localization to endoplasmic reticulum
LZ756_08265	COG0084	hydrolase, TatD family'
LZ756_08275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZ756_08275	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ756_08310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ756_08345	COG2091	lysine biosynthetic process via aminoadipic acid
LZ756_08355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZ756_08360	COG1301	dicarboxylic acid transport
LZ756_08380	COG0339	signal peptide processing
LZ756_08390	COG0285	dihydrofolate synthase activity
LZ756_08420	COG0784	Response regulator, receiver
LZ756_08420	COG2198	Histidine kinase
LZ756_08420	COG0643	Histidine kinase
LZ756_08425	COG0840	transmembrane signaling receptor activity
LZ756_08470	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZ756_08475	COG0596	Alpha beta hydrolase
LZ756_08495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ756_08505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZ756_08510	COG0138	bifunctional purine biosynthesis protein purh
LZ756_08520	COG1289	transmembrane transporter activity
LZ756_08525	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZ756_08540	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZ756_08550	COG0557	exoribonuclease II activity
LZ756_08560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ756_08565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZ756_08600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZ756_08635	COG0778	Nitroreductase
LZ756_08645	COG0006	proline dipeptidase activity
LZ756_08670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZ756_08690	COG0025	NhaP-type Na H and K H
LZ756_08700	COG2925	Exonuclease
LZ756_08765	COG1028	Short-chain dehydrogenase reductase Sdr
LZ756_08770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ756_08825	COG4962	Type ii secretion system protein e
LZ756_08855	COG2902	Dehydrogenase
LZ756_08860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ756_08865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ756_08970	COG2850	peptidyl-arginine hydroxylation
LZ756_08975	COG0567	Dehydrogenase, E1 component
LZ756_09000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZ756_09060	COG0583	DNA-binding transcription factor activity
LZ756_09065	COG3634	alkyl hydroperoxide reductase activity
LZ756_09080	COG1450	Type ii and iii secretion system protein
LZ756_09095	COG3166	PFAM Fimbrial assembly family protein
LZ756_09100	COG3156	type II secretion system protein K
LZ756_09105	COG4795	General secretion pathway protein
LZ756_09110	COG2165	general secretion pathway protein
LZ756_09115	COG4970	Tfp pilus assembly protein FimT
LZ756_09120	COG2165	general secretion pathway protein
LZ756_09125	COG1459	type II secretion system
LZ756_09130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZ756_09135	COG5295	Hep Hag repeat protein
LZ756_09170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZ756_09185	COG1561	YicC-like family, N-terminal region
LZ756_09195	COG1758	RNA polymerase activity
LZ756_09210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZ756_09265	COG0308	aminopeptidase N
LZ756_09315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZ756_09360	COG0489	protein tyrosine kinase activity
LZ756_09370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZ756_09425	COG2267	carboxylic ester hydrolase activity
LZ756_09460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZ756_09535	COG1605	Chorismate mutase
LZ756_09535	COG0077	Prephenate dehydratase
LZ756_09550	COG1668	transmembrane transport
LZ756_09555	COG4555	ABC transporter
LZ756_09580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZ756_09590	COG0287	Prephenate dehydrogenase
LZ756_09590	COG1605	Chorismate mutase
LZ756_09595	COG0484	heat shock protein binding
LZ756_09625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ756_09650	COG1278	Cold shock
LZ756_09660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZ756_09670	COG2954	triphosphatase activity
LZ756_09685	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZ756_09690	COG0438	transferase activity, transferring glycosyl groups
LZ756_09700	COG0438	transferase activity, transferring glycosyl groups
LZ756_09755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ756_09760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ756_09775	COG1064	alcohol dehydrogenase
LZ756_09795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ756_09810	COG0436	Aminotransferase
LZ756_09865	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LZ756_09865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ756_09915	COG0196	riboflavin kinase activity
LZ756_09920	COG0728	peptidoglycan biosynthetic process
LZ756_09925	COG0268	Binds directly to 16S ribosomal RNA
LZ756_09945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZ756_09980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZ756_09995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZ756_10050	COG0395	ABC-type sugar transport system, permease component
LZ756_10055	COG1175	transmembrane transport
LZ756_10100	COG0436	Aminotransferase
LZ756_10160	COG5434	Belongs to the glycosyl hydrolase 28 family
LZ756_10180	COG0402	S-adenosylhomocysteine deaminase activity
LZ756_10190	COG1509	lysine 2,3-aminomutase activity
LZ756_10225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZ756_10230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZ756_10245	COG1028	Short-chain dehydrogenase reductase Sdr
LZ756_10300	COG0142	geranyltranstransferase activity
LZ756_10325	COG1301	dicarboxylic acid transport
LZ756_10330	COG0791	NLP P60 protein
LZ756_10335	COG0791	NLP P60 protein
LZ756_10345	COG2311	Membrane
LZ756_10355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZ756_10415	COG0351	phosphomethylpyrimidine kinase
LZ756_10415	COG0352	thiamine-phosphate diphosphorylase activity
LZ756_10425	COG1324	tolerance protein
LZ756_10435	COG0459	protein refolding
LZ756_10475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ756_10480	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZ756_10495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZ756_10515	COG4774	siderophore transport
LZ756_10540	COG1477	protein flavinylation
LZ756_10545	COG1555	photosystem II stabilization
LZ756_10550	COG3178	'Phosphotransferase
LZ756_10555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZ756_10565	COG0628	permease
LZ756_10585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZ756_10610	COG3590	peptidase
LZ756_10655	COG0805	protein transport
LZ756_10665	COG0519	Catalyzes the synthesis of GMP from XMP
LZ756_10665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZ756_10680	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZ756_10695	COG3107	peptidoglycan biosynthetic process
LZ756_10715	COG2878	Part of a membrane complex involved in electron transport
LZ756_10770	COG0358	DNA primase activity
LZ756_10790	COG4197	protein conserved in bacteria, prophage-related
LZ756_10855	COG4969	Belongs to the N-Me-Phe pilin family
LZ756_10870	COG0629	single-stranded DNA binding
LZ756_10930	COG3657	addiction module killer protein
LZ756_10935	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ756_10985	COG3657	addiction module killer protein
LZ756_10990	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ756_11020	COG0675	Transposase, IS605 OrfB family
LZ756_11065	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ756_11070	COG0488	(ABC) transporter
LZ756_11090	COG4651	solute:proton antiporter activity
LZ756_11090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZ756_11120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ756_11150	COG0859	PFAM glycosyl transferase family 9
LZ756_11165	COG0631	protein serine/threonine phosphatase activity
LZ756_11170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ756_11175	COG0328	RNA-DNA hybrid ribonuclease activity
LZ756_11200	COG2183	response to ionizing radiation
LZ756_11215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZ756_11220	COG3118	belongs to the thioredoxin family
LZ756_11270	COG2951	lytic endotransglycosylase activity
LZ756_11400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZ756_11410	COG1199	ATP-dependent helicase activity
LZ756_11420	COG0288	reversible hydration of carbon dioxide
LZ756_11445	COG2011	ABC-type metal ion transport system permease component
LZ756_11460	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ756_11475	COG0626	cystathionine gamma-synthase activity
LZ756_11480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZ756_11485	COG0739	heme binding
LZ756_11500	COG1238	metal cluster binding
LZ756_11535	COG1388	LysM domain
LZ756_11535	COG3858	chitin binding
LZ756_11540	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZ756_11550	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ756_11565	COG3537	Alpha-1,2-mannosidase
LZ756_11595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ756_11600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ756_11640	COG0469	pyruvate kinase activity
LZ756_11660	COG0735	belongs to the Fur family
LZ756_11685	COG0612	Peptidase, M16
LZ756_11705	COG4305	rare lipoprotein A
LZ756_11715	COG0739	heme binding
LZ756_11725	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LZ756_11730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZ756_11740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZ756_11770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZ756_11785	COG3116	cell division
LZ756_11800	COG3273	potassium ion transport
LZ756_11800	COG0471	metal ion transport
LZ756_11855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ756_11920	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZ756_11925	COG0802	atpase or kinase
LZ756_11930	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZ756_11930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZ756_12005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZ756_12030	COG0745	RESPONSE REGULATOR receiver
LZ756_12035	COG0642	Histidine kinase
LZ756_12045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZ756_12090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZ756_12100	COG2831	hemolysin activation secretion protein
LZ756_12125	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZ756_12170	COG0316	Belongs to the HesB IscA family
LZ756_12210	COG0697	spore germination
LZ756_12215	COG0671	phosphoesterase, PA-phosphatase related
LZ756_12220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LZ756_12230	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZ756_12250	COG1132	(ABC) transporter
LZ756_12260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZ756_12265	COG1538	Outer membrane efflux protein
LZ756_12295	COG0745	RESPONSE REGULATOR receiver
LZ756_12300	COG4783	chaperone-mediated protein folding
LZ756_12310	COG0473	3-isopropylmalate dehydrogenase activity
LZ756_12325	COG3083	sulfuric ester hydrolase activity
LZ756_12330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZ756_12355	COG0564	pseudouridine synthase activity
LZ756_12360	COG1530	ribonuclease E activity
LZ756_12365	COG2197	response regulator
LZ756_12380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ756_12395	COG0488	(ABC) transporter
LZ756_12410	COG1278	Cold shock
LZ756_12510	COG0012	GTP binding
LZ756_12525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZ756_12610	COG2095	MarC family integral membrane protein
LZ756_12620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ756_12645	COG2132	Multicopper oxidase
LZ756_12655	COG0210	DNA helicase
LZ756_12665	COG0616	signal peptide processing
LZ756_12685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZ756_12700	COG2201	protein-glutamate methylesterase activity
LZ756_12705	COG2177	Part of the ABC transporter FtsEX involved in
LZ756_12710	COG2884	Cell division ATP-binding protein ftsE
LZ756_12720	COG3118	belongs to the thioredoxin family
LZ756_12725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZ756_12740	COG0793	Belongs to the peptidase S41A family
LZ756_12745	COG4942	peptidase
LZ756_12765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ756_12770	COG0493	'glutamate synthase
LZ756_12775	COG0070	glutamate synthase
LZ756_12775	COG0069	glutamate synthase activity
LZ756_12775	COG0067	glutamate synthase
LZ756_12830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ756_12895	COG4942	peptidase
LZ756_13130	COG3736	Type IV secretory pathway, component VirB8
LZ756_13180	COG0675	Transposase, IS605 OrfB family
LZ756_13215	COG3077	Addiction module antitoxin, RelB DinJ family
LZ756_13225	COG0675	Transposase, IS605 OrfB family
LZ756_13265	COG2027	D-alanyl-D-alanine carboxypeptidase