locus-tag	class	description
GT347_00040	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_00050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GT347_00060	COG0156	8-amino-7-oxononanoate synthase activity
GT347_00070	COG2183	response to ionizing radiation
GT347_00080	COG0475	glutathione-regulated potassium exporter activity
GT347_00080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT347_00120	COG0411	ABC transporter
GT347_00190	COG0716	FMN binding
GT347_00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_00220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GT347_00240	COG0583	DNA-binding transcription factor activity
GT347_00245	COG0436	Aminotransferase
GT347_00260	COG0584	glycerophosphoryl diester phosphodiesterase
GT347_00265	COG0789	Transcriptional regulator
GT347_00285	COG0587	DNA-directed DNA polymerase activity
GT347_00300	COG1132	(ABC) transporter
GT347_00310	COG0642	Histidine kinase
GT347_00315	COG0745	RESPONSE REGULATOR receiver
GT347_00345	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GT347_00345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_00350	COG0840	transmembrane signaling receptor activity
GT347_00365	COG0175	sulfate reduction
GT347_00375	COG2895	sulfate adenylyltransferase (ATP) activity
GT347_00380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GT347_00385	COG0492	ferredoxin-NADP+ reductase activity
GT347_00400	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_00420	COG1609	Transcriptional regulator
GT347_00430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_00435	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_00440	COG1960	acyl-CoA dehydrogenase activity
GT347_00450	COG3622	Belongs to the hyi family
GT347_00455	COG3395	kinase activity
GT347_00475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT347_00485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_00525	COG1476	TRANSCRIPTIONal
GT347_00545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GT347_00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT347_00570	COG2066	Belongs to the glutaminase family
GT347_00580	COG2918	glutathione biosynthetic process
GT347_00590	COG0400	carboxylic ester hydrolase activity
GT347_00630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_00630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_00645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GT347_00650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT347_00655	COG0436	Aminotransferase
GT347_00675	COG0824	Thioesterase
GT347_00685	COG0848	biopolymer transport protein
GT347_00705	COG3791	Glutathione-dependent formaldehyde-activating
GT347_00710	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GT347_00720	COG1011	Hydrolase
GT347_00735	COG1196	nuclear chromosome segregation
GT347_00735	COG3264	Mechanosensitive ion channel
GT347_00740	COG0628	permease
GT347_00770	COG0840	transmembrane signaling receptor activity
GT347_00780	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GT347_00800	COG1845	cytochrome c oxidase, subunit III
GT347_00805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GT347_00810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT347_00815	COG0477	Major facilitator Superfamily
GT347_00840	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_00845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_00855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_00865	COG3415	Transposase
GT347_00865	COG2801	Transposase and inactivated derivatives
GT347_00875	COG2207	Transcriptional regulator
GT347_00880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_00885	COG2354	Protein conserved in bacteria
GT347_00890	COG0047	phosphoribosylformylglycinamidine synthase activity
GT347_00890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GT347_00895	COG0024	Methionine aminopeptidase
GT347_00910	COG2186	Transcriptional regulator
GT347_00930	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GT347_00945	COG0765	amino acid transport
GT347_00950	COG4597	amino acid ABC transporter
GT347_00960	COG0242	peptide deformylase activity
GT347_00985	COG1196	nuclear chromosome segregation
GT347_01000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT347_01005	COG0058	SHG alpha-glucan phosphorylase activity
GT347_01010	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_01015	COG0436	Aminotransferase
GT347_01025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_01030	COG2890	protein-(glutamine-N5) methyltransferase activity
GT347_01055	COG3415	Transposase
GT347_01055	COG2801	Transposase and inactivated derivatives
GT347_01070	COG4191	Histidine kinase
GT347_01075	COG3920	Histidine kinase
GT347_01080	COG4566	intracellular signal transduction
GT347_01085	COG4566	intracellular signal transduction
GT347_01125	COG1116	anion transmembrane transporter activity
GT347_01140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_01145	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_01150	COG1802	Transcriptional regulator
GT347_01175	COG1335	isochorismatase
GT347_01180	COG2175	clavaminate synthase activity
GT347_01185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GT347_01190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_01265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GT347_01290	COG5002	protein histidine kinase activity
GT347_01300	COG0745	RESPONSE REGULATOR receiver
GT347_01375	COG0037	tRNA processing
GT347_01380	COG0825	malonyl-CoA metabolic process
GT347_01390	COG0215	cysteine-tRNA ligase activity
GT347_01405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GT347_01415	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_01435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_01440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT347_01450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_01475	COG1196	nuclear chromosome segregation
GT347_01490	COG1752	Esterase of the alpha-beta hydrolase superfamily
GT347_01510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GT347_01515	COG3300	MHYT domain
GT347_01515	COG5001	Diguanylate cyclase
GT347_01555	COG0583	DNA-binding transcription factor activity
GT347_01560	COG0693	protein deglycase activity
GT347_01580	COG0612	Peptidase, M16
GT347_01585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GT347_01585	COG0519	Catalyzes the synthesis of GMP from XMP
GT347_01605	COG2867	negative regulation of translational initiation
GT347_01610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GT347_01615	COG0154	amidase activity
GT347_01620	COG1126	abc transporter atp-binding protein
GT347_01625	COG1137	ATPase activity
GT347_01635	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_01675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GT347_01680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GT347_01685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GT347_01690	COG0195	Participates in both transcription termination and antitermination
GT347_01690	COG2251	uridine kinase activity
GT347_01695	COG0779	Required for maturation of 30S ribosomal subunits
GT347_01705	COG4172	Belongs to the ABC transporter superfamily
GT347_01710	COG4239	(ABC) transporter, permease
GT347_01715	COG4174	ABC transporter (Permease)
GT347_01720	COG4166	transmembrane transport
GT347_01725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GT347_01730	COG1793	dna ligase
GT347_01800	COG2204	response regulator
GT347_01815	COG1280	lysine exporter protein (LysE YggA)
GT347_01830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_01840	COG2207	Transcriptional regulator
GT347_01850	COG0657	acetylesterase activity
GT347_01855	COG0235	Class ii aldolase
GT347_01865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GT347_01875	COG0183	Belongs to the thiolase family
GT347_01885	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_01890	COG2188	Transcriptional regulator
GT347_01940	COG1960	acyl-CoA dehydrogenase activity
GT347_01945	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
GT347_01975	COG0724	RNA recognition motif
GT347_01980	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GT347_01985	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GT347_01990	COG1414	Transcriptional regulator
GT347_01995	COG0583	DNA-binding transcription factor activity
GT347_02020	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_02030	COG0840	transmembrane signaling receptor activity
GT347_02060	COG3287	FIST C domain
GT347_02060	COG2200	EAL domain
GT347_02060	COG2199	diguanylate cyclase activity
GT347_02085	COG0642	Histidine kinase
GT347_02090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GT347_02115	COG0076	glutamate decarboxylase activity
GT347_02120	COG2982	Protein involved in outer membrane biogenesis
GT347_02135	COG1643	Atp-dependent helicase
GT347_02140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GT347_02140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT347_02145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GT347_02155	COG4208	sulfate ABC transporter
GT347_02160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GT347_02165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GT347_02170	COG0450	alkyl hydroperoxide reductase
GT347_02185	COG1183	phosphatidylcholine synthase activity
GT347_02195	COG0440	acetolactate synthase activity
GT347_02200	COG0028	Belongs to the TPP enzyme family
GT347_02225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GT347_02235	COG0347	Belongs to the P(II) protein family
GT347_02245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GT347_02255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GT347_02260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GT347_02265	COG0746	molybdenum cofactor guanylyltransferase activity
GT347_02270	COG0328	RNA-DNA hybrid ribonuclease activity
GT347_02275	COG2226	methyltransferase
GT347_02280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT347_02285	COG0741	lytic transglycosylase activity
GT347_02285	COG1388	LysM domain
GT347_02295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_02380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GT347_02410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GT347_02415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GT347_02425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GT347_02445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GT347_02450	COG0028	Belongs to the TPP enzyme family
GT347_02455	COG0254	rRNA binding
GT347_02465	COG0534	Mate efflux family protein
GT347_02485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT347_02490	COG0581	inorganic phosphate transmembrane transporter activity
GT347_02495	COG0573	inorganic phosphate transmembrane transporter activity
GT347_02500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GT347_02505	COG0248	Ppx GppA phosphatase
GT347_02530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GT347_02535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GT347_02540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT347_02545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GT347_02550	COG1534	Rna-binding protein
GT347_02565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT347_02575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GT347_02580	COG0505	Belongs to the CarA family
GT347_02585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT347_02590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GT347_02595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_02600	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_02605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT347_02610	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_02625	COG0750	zinc metalloprotease
GT347_02630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GT347_02635	COG0575	Belongs to the CDS family
GT347_02645	COG0233	cytoplasmic translational termination
GT347_02650	COG0528	UMP kinase activity
GT347_02655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GT347_02660	COG0052	Belongs to the universal ribosomal protein uS2 family
GT347_02665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GT347_02685	COG0557	exoribonuclease II activity
GT347_02695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT347_02740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GT347_02775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT347_02785	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_02795	COG0745	RESPONSE REGULATOR receiver
GT347_02805	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GT347_02805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GT347_02810	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GT347_02810	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GT347_02815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GT347_02820	COG0560	Phosphoserine phosphatase
GT347_02835	COG0583	DNA-binding transcription factor activity
GT347_02840	COG1304	FMN binding
GT347_02865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GT347_02870	COG0513	Belongs to the DEAD box helicase family
GT347_02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_02895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GT347_02920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GT347_02935	COG4977	sequence-specific DNA binding
GT347_02955	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GT347_02965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GT347_02985	COG1492	cobalamin metabolic process
GT347_03000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GT347_03005	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GT347_03010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GT347_03015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT347_03020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GT347_03030	COG1797	cobyrinic acid a,c-diamide synthase activity
GT347_03035	COG4206	TonB-dependent receptor
GT347_03060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GT347_03065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GT347_03090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_03105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT347_03125	COG1802	Transcriptional regulator
GT347_03145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT347_03155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_03160	COG2205	protein histidine kinase activity
GT347_03165	COG0745	RESPONSE REGULATOR receiver
GT347_03170	COG0840	transmembrane signaling receptor activity
GT347_03230	COG2080	2 iron, 2 sulfur cluster binding
GT347_03235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GT347_03240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_03245	COG2951	lytic endotransglycosylase activity
GT347_03265	COG0628	permease
GT347_03280	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GT347_03290	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GT347_03295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GT347_03300	COG3639	organic phosphonate transmembrane transporter activity
GT347_03305	COG3639	organic phosphonate transmembrane transporter activity
GT347_03325	COG2203	Gaf domain
GT347_03325	COG3706	GGDEF domain
GT347_03325	COG5001	Diguanylate cyclase
GT347_03325	COG4251	negative regulation of phosphorylation
GT347_03330	COG0745	RESPONSE REGULATOR receiver
GT347_03345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GT347_03355	COG2885	chlorophyll binding
GT347_03360	COG0823	Involved in the tonB-independent uptake of proteins
GT347_03365	COG1132	(ABC) transporter
GT347_03375	COG1530	ribonuclease E activity
GT347_03380	COG0424	maF-like protein
GT347_03385	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GT347_03390	COG0799	negative regulation of ribosome biogenesis
GT347_03400	COG0408	coproporphyrinogen oxidase activity
GT347_03410	COG0217	transcriptional regulatory protein
GT347_03415	COG0433	COG0433 Predicted ATPase
GT347_03420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GT347_03425	COG1744	ABC transporter substrate-binding protein PnrA-like
GT347_03450	COG0402	S-adenosylhomocysteine deaminase activity
GT347_03490	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GT347_03505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT347_03535	COG1414	Transcriptional regulator
GT347_03540	COG3706	GGDEF domain
GT347_03565	COG0583	DNA-binding transcription factor activity
GT347_03590	COG0346	lactoylglutathione lyase activity
GT347_03595	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GT347_03600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GT347_03635	COG0800	Aldolase
GT347_03640	COG0129	dihydroxy-acid dehydratase activity
GT347_03645	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GT347_03650	COG2032	superoxide dismutase activity
GT347_03660	COG0259	pyridoxamine-phosphate oxidase activity
GT347_03690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_03695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GT347_03720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GT347_03735	COG3657	addiction module killer protein
GT347_03755	COG2133	pyrroloquinoline quinone binding
GT347_03760	COG0791	NLP P60 protein
GT347_03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT347_03770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GT347_03775	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT347_03780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GT347_03790	COG4566	intracellular signal transduction
GT347_03795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GT347_03810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GT347_03815	COG0167	dihydroorotate dehydrogenase activity
GT347_03825	COG0783	Belongs to the Dps family
GT347_03855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_03870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GT347_03875	COG1074	ATP-dependent DNA helicase activity
GT347_03880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GT347_03895	COG0625	glutathione transferase activity
GT347_03900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT347_03900	COG1017	nitric oxide dioxygenase activity
GT347_03910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GT347_03920	COG0443	Heat shock 70 kDa protein
GT347_03930	COG0316	Belongs to the HesB IscA family
GT347_03935	COG0822	iron-sulfur transferase activity
GT347_03940	COG1104	cysteine desulfurase activity
GT347_03945	COG1959	2 iron, 2 sulfur cluster binding
GT347_03950	COG0556	nucleotide-excision repair
GT347_03965	COG2878	Part of a membrane complex involved in electron transport
GT347_03975	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_03980	COG2030	dehydratase
GT347_03995	COG1960	acyl-CoA dehydrogenase activity
GT347_04000	COG0427	acetyl-CoA hydrolase
GT347_04005	COG2301	Belongs to the HpcH HpaI aldolase family
GT347_04015	COG2808	Putative FMN-binding domain
GT347_04020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_04025	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_04030	COG0154	amidase activity
GT347_04035	COG1414	Transcriptional regulator
GT347_04045	COG2814	Major facilitator Superfamily
GT347_04065	COG1595	DNA-templated transcription, initiation
GT347_04105	COG4651	solute:proton antiporter activity
GT347_04105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT347_04110	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_04115	COG0183	Belongs to the thiolase family
GT347_04120	COG3243	poly(R)-hydroxyalkanoic acid synthase
GT347_04150	COG2831	hemolysin activation secretion protein
GT347_04190	COG0625	glutathione transferase activity
GT347_04195	COG0667	Aldo Keto reductase
GT347_04220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GT347_04225	COG1570	exodeoxyribonuclease VII activity
GT347_04230	COG0811	peptide transport
GT347_04235	COG0848	biopolymer transport protein
GT347_04240	COG1663	tetraacyldisaccharide 4'-kinase activity
GT347_04245	COG2835	tetraacyldisaccharide 4'-kinase activity
GT347_04250	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GT347_04275	COG0563	adenylate kinase activity
GT347_04280	COG0252	asparaginase activity
GT347_04285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT347_04295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_04305	COG1024	Enoyl-CoA hydratase
GT347_04355	COG0667	Aldo Keto reductase
GT347_04390	COG2308	Evidence 4 Homologs of previously reported genes of
GT347_04415	COG0741	lytic transglycosylase activity
GT347_04430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_04435	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GT347_04440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GT347_04450	COG2850	peptidyl-arginine hydroxylation
GT347_04455	COG1047	Peptidyl-prolyl cis-trans
GT347_04465	COG0756	dUTP diphosphatase activity
GT347_04470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GT347_04475	COG0504	CTP synthase activity
GT347_04480	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GT347_04490	COG0148	phosphopyruvate hydratase activity
GT347_04495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GT347_04520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GT347_04530	COG2833	Protein of unknown function (DUF455)
GT347_04540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GT347_04565	COG4974	Belongs to the 'phage' integrase family
GT347_04580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GT347_04585	COG0802	atpase or kinase
GT347_04590	COG0860	N-Acetylmuramoyl-L-alanine amidase
GT347_04600	COG0586	Pfam SNARE associated Golgi protein
GT347_04605	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GT347_04615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GT347_04620	COG1136	(ABC) transporter
GT347_04660	COG3237	CsbD-like
GT347_04670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GT347_04675	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GT347_04720	COG3158	transport of potassium into the cell
GT347_04745	COG0542	response to heat
GT347_04775	COG0297	glycogen (starch) synthase activity
GT347_04780	COG1640	4-alpha-glucanotransferase
GT347_04795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GT347_04800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GT347_04810	COG0617	tRNA 3'-terminal CCA addition
GT347_04820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GT347_04830	COG0728	peptidoglycan biosynthetic process
GT347_04835	COG0268	Binds directly to 16S ribosomal RNA
GT347_04855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GT347_04860	COG2202	Pas domain
GT347_04860	COG2200	EAL domain
GT347_04860	COG2199	diguanylate cyclase activity
GT347_04890	COG1845	cytochrome c oxidase, subunit III
GT347_04900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT347_04935	COG0437	4 iron, 4 sulfur cluster binding
GT347_04960	COG0308	aminopeptidase N
GT347_04965	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GT347_05005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_05035	COG0811	peptide transport
GT347_05080	COG3591	Belongs to the peptidase S1B family
GT347_05080	COG1864	DNA RNA non-specific endonuclease
GT347_05090	COG0583	DNA-binding transcription factor activity
GT347_05100	COG1309	transcriptional regulator
GT347_05110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_05115	COG0156	8-amino-7-oxononanoate synthase activity
GT347_05125	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_05135	COG1285	pathogenesis
GT347_05140	COG3046	protein related to deoxyribodipyrimidine photolyase
GT347_05145	COG0583	DNA-binding transcription factor activity
GT347_05150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_05165	COG0484	heat shock protein binding
GT347_05200	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_05235	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GT347_05240	COG2267	carboxylic ester hydrolase activity
GT347_05260	COG0840	transmembrane signaling receptor activity
GT347_05265	COG2198	Histidine kinase
GT347_05265	COG0643	Histidine kinase
GT347_05270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_05285	COG0583	DNA-binding transcription factor activity
GT347_05300	COG1012	belongs to the aldehyde dehydrogenase family
GT347_05325	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_05330	COG2079	MmgE PrpD family protein
GT347_05335	COG0583	DNA-binding transcription factor activity
GT347_05350	COG0765	amino acid transport
GT347_05360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_05370	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_05395	COG1414	Transcriptional regulator
GT347_05405	COG2301	Belongs to the HpcH HpaI aldolase family
GT347_05410	COG0427	acetyl-CoA hydrolase
GT347_05415	COG1024	Enoyl-CoA hydratase
GT347_05425	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_05430	COG0318	PFAM AMP-dependent synthetase and ligase
GT347_05435	COG2188	Transcriptional regulator
GT347_05465	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_05510	COG0583	DNA-binding transcription factor activity
GT347_05520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT347_05530	COG0583	DNA-binding transcription factor activity
GT347_05535	COG0402	S-adenosylhomocysteine deaminase activity
GT347_05545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_05570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GT347_05580	COG0835	chemotaxis
GT347_05585	COG0840	transmembrane signaling receptor activity
GT347_05590	COG2198	Histidine kinase
GT347_05590	COG0643	Histidine kinase
GT347_05600	COG2201	protein-glutamate methylesterase activity
GT347_05605	COG0840	transmembrane signaling receptor activity
GT347_05615	COG2814	Major facilitator Superfamily
GT347_05620	COG0583	DNA-binding transcription factor activity
GT347_05625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT347_05675	COG0589	response to stress
GT347_05690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GT347_05695	COG0724	RNA recognition motif
GT347_05705	COG0459	protein refolding
GT347_05730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT347_05745	COG1063	alcohol dehydrogenase
GT347_05770	COG4191	Histidine kinase
GT347_05770	COG0745	RESPONSE REGULATOR receiver
GT347_05770	COG2205	protein histidine kinase activity
GT347_05780	COG0024	Methionine aminopeptidase
GT347_05795	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_05805	COG0583	DNA-binding transcription factor activity
GT347_05840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_05855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_05860	COG2186	Transcriptional regulator
GT347_05885	COG0243	molybdopterin cofactor binding
GT347_05895	COG0642	Histidine kinase
GT347_05900	COG0745	RESPONSE REGULATOR receiver
GT347_05910	COG2814	Major facilitator Superfamily
GT347_05915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_05945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_05950	COG0066	3-isopropylmalate dehydratase activity
GT347_05960	COG2188	Transcriptional regulator
GT347_06010	COG1902	pentaerythritol trinitrate reductase activity
GT347_06015	COG0154	amidase activity
GT347_06065	COG1136	(ABC) transporter
GT347_06095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GT347_06105	COG0613	PHP domain protein
GT347_06115	COG0009	L-threonylcarbamoyladenylate synthase
GT347_06120	COG1994	Peptidase M50
GT347_06125	COG0180	Tryptophanyl-tRNA synthetase
GT347_06170	COG1620	l-lactate permease
GT347_06175	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_06185	COG0583	DNA-binding transcription factor activity
GT347_06210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_06220	COG2954	triphosphatase activity
GT347_06240	COG0564	pseudouridine synthase activity
GT347_06295	COG0514	ATP-dependent DNA helicase (RecQ)
GT347_06310	COG0633	Ferredoxin
GT347_06325	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_06335	COG4336	lyase activity
GT347_06345	COG0848	biopolymer transport protein
GT347_06350	COG0811	peptide transport
GT347_06370	COG1012	belongs to the aldehyde dehydrogenase family
GT347_06375	COG0626	cystathionine gamma-synthase activity
GT347_06380	COG0300	oxidoreductase activity
GT347_06385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_06390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_06420	COG1253	flavin adenine dinucleotide binding
GT347_06430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GT347_06435	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GT347_06440	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GT347_06445	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_06450	COG0583	DNA-binding transcription factor activity
GT347_06455	COG4993	Dehydrogenase
GT347_06465	COG3119	arylsulfatase activity
GT347_06475	COG5002	protein histidine kinase activity
GT347_06505	COG1132	(ABC) transporter
GT347_06515	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GT347_06520	COG2207	Transcriptional regulator
GT347_06525	COG2223	nitrite transmembrane transporter activity
GT347_06550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT347_06560	COG1595	DNA-templated transcription, initiation
GT347_06570	COG2203	Gaf domain
GT347_06570	COG3706	GGDEF domain
GT347_06570	COG4251	negative regulation of phosphorylation
GT347_06570	COG5001	Diguanylate cyclase
GT347_06575	COG0583	DNA-binding transcription factor activity
GT347_06605	COG2900	Belongs to the SlyX family
GT347_06610	COG0579	oxidoreductase
GT347_06620	COG1414	Transcriptional regulator
GT347_06645	COG1609	Transcriptional regulator
GT347_06655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_06680	COG0217	transcriptional regulatory protein
GT347_06700	COG2814	Major facilitator Superfamily
GT347_06710	COG1309	transcriptional regulator
GT347_06725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GT347_06770	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_06780	COG2378	regulation of single-species biofilm formation
GT347_06800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_06810	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_06840	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_06845	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_06855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GT347_06865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GT347_06875	COG0110	maltose O-acetyltransferase activity
GT347_06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_06925	COG0601	transmembrane transport
GT347_06930	COG0747	negative chemotaxis
GT347_06935	COG0402	S-adenosylhomocysteine deaminase activity
GT347_06945	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GT347_06950	COG0583	DNA-binding transcription factor activity
GT347_06955	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_06960	COG0300	oxidoreductase activity
GT347_06975	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT347_06980	COG0583	DNA-binding transcription factor activity
GT347_06985	COG0534	Mate efflux family protein
GT347_07005	COG2995	paraquat-inducible protein a
GT347_07010	COG2995	paraquat-inducible protein a
GT347_07015	COG3008	intermembrane lipid transfer
GT347_07015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT347_07035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_07040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_07050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_07060	COG3415	Transposase
GT347_07060	COG2801	Transposase and inactivated derivatives
GT347_07100	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_07105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GT347_07120	COG0583	DNA-binding transcription factor activity
GT347_07130	COG2814	Major facilitator Superfamily
GT347_07180	COG2186	Transcriptional regulator
GT347_07185	COG1312	Catalyzes the dehydration of D-mannonate
GT347_07200	COG0154	amidase activity
GT347_07210	COG0402	S-adenosylhomocysteine deaminase activity
GT347_07225	COG3842	ATPase activity
GT347_07235	COG0402	S-adenosylhomocysteine deaminase activity
GT347_07245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT347_07250	COG0402	S-adenosylhomocysteine deaminase activity
GT347_07255	COG3842	ATPase activity
GT347_07260	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_07265	COG1177	transmembrane transport
GT347_07275	COG1321	iron dependent repressor
GT347_07280	COG1609	Transcriptional regulator
GT347_07295	COG0601	transmembrane transport
GT347_07315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT347_07320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GT347_07325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GT347_07340	COG1561	YicC-like family, N-terminal region
GT347_07345	COG0194	GDP metabolic process
GT347_07350	COG1758	RNA polymerase activity
GT347_07355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT347_07370	COG0406	alpha-ribazole phosphatase activity
GT347_07385	COG0302	gtp cyclohydrolase
GT347_07390	COG0745	RESPONSE REGULATOR receiver
GT347_07410	COG0494	nUDIX hydrolase
GT347_07415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GT347_07435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GT347_07450	COG2226	methyltransferase
GT347_07475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_07480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GT347_07485	COG2188	Transcriptional regulator
GT347_07490	COG1960	acyl-CoA dehydrogenase activity
GT347_07500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GT347_07500	COG0189	ligase activity
GT347_07505	COG0189	ligase activity
GT347_07505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GT347_07510	COG1132	(ABC) transporter
GT347_07520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GT347_07530	COG3437	response regulator, receiver
GT347_07550	COG1459	type II secretion system
GT347_07555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_07560	COG0720	synthase
GT347_07565	COG0602	queuosine metabolic process
GT347_07570	COG3842	ATPase activity
GT347_07580	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_07585	COG1177	transmembrane transport
GT347_07600	COG2205	protein histidine kinase activity
GT347_07600	COG0784	Response regulator, receiver
GT347_07605	COG0792	nuclease activity
GT347_07615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_07620	COG1136	(ABC) transporter
GT347_07620	COG0577	efflux transmembrane transporter activity
GT347_07640	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GT347_07645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GT347_07655	COG0642	Histidine kinase
GT347_07660	COG0745	RESPONSE REGULATOR receiver
GT347_07680	COG3045	CreA protein
GT347_07685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT347_07700	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GT347_07725	COG0501	Belongs to the peptidase M48B family
GT347_07735	COG0418	dihydroorotase activity
GT347_07750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_07770	COG1126	abc transporter atp-binding protein
GT347_07775	COG0765	amino acid transport
GT347_07780	COG0765	amino acid transport
GT347_07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_07790	COG0583	DNA-binding transcription factor activity
GT347_07795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_07800	COG5265	(ABC) transporter
GT347_07810	COG1024	Enoyl-CoA hydratase
GT347_07820	COG1309	transcriptional regulator
GT347_07825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT347_07830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT347_07865	COG0438	transferase activity, transferring glycosyl groups
GT347_07865	COG1216	Glycosyl transferase, family 2
GT347_07880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GT347_07895	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GT347_07930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT347_07935	COG2201	protein-glutamate methylesterase activity
GT347_07940	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GT347_07945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GT347_07950	COG0835	chemotaxis
GT347_07955	COG2198	Histidine kinase
GT347_07955	COG0643	Histidine kinase
GT347_07960	COG0784	Response regulator, receiver
GT347_07960	COG2205	protein histidine kinase activity
GT347_07975	COG2197	response regulator
GT347_07980	COG1684	flagellar biosynthetic protein fliR
GT347_07985	COG1987	bacterial-type flagellum assembly
GT347_08000	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT347_08040	COG1766	The M ring may be actively involved in energy transduction
GT347_08060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GT347_08065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GT347_08080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT347_08150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GT347_08160	COG0745	RESPONSE REGULATOR receiver
GT347_08165	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GT347_08180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_08190	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_08205	COG1191	sigma factor activity
GT347_08225	COG1815	bacterial-type flagellum-dependent cell motility
GT347_08230	COG1558	bacterial-type flagellum-dependent cell motility
GT347_08245	COG4787	bacterial-type flagellum-dependent cell motility
GT347_08250	COG4786	Flagellar basal body rod
GT347_08255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT347_08260	COG1706	bacterial-type flagellum-dependent cell motility
GT347_08265	COG1705	Flagellar rod assembly protein muramidase FlgJ
GT347_08265	COG3951	Flagellar rod assembly protein muramidase FlgJ
GT347_08290	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_08295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GT347_08305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_08310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_08335	COG1335	isochorismatase
GT347_08360	COG0123	including yeast histone deacetylase and acetoin utilization protein
GT347_08430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT347_08450	COG0285	dihydrofolate synthase activity
GT347_08455	COG1393	Belongs to the ArsC family
GT347_08470	COG1595	DNA-templated transcription, initiation
GT347_08475	COG3123	guanosine phosphorylase activity
GT347_08480	COG0137	argininosuccinate synthase activity
GT347_08490	COG1872	DUF167
GT347_08500	COG0736	holo-[acyl-carrier-protein] synthase activity
GT347_08505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GT347_08510	COG1381	Involved in DNA repair and RecF pathway recombination
GT347_08515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GT347_08520	COG0571	ribonuclease III activity
GT347_08530	COG0681	Belongs to the peptidase S26 family
GT347_08535	COG0481	GTPase activity
GT347_08540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT347_08565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GT347_08570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT347_08575	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_08585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT347_08590	COG0416	fatty acid biosynthetic process
GT347_08595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GT347_08600	COG1399	metal-binding, possibly nucleic acid-binding protein
GT347_08605	COG0424	maF-like protein
GT347_08615	COG0616	signal peptide processing
GT347_08615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GT347_08625	COG0546	phosphoglycolate phosphatase activity
GT347_08635	COG1530	ribonuclease E activity
GT347_08640	COG3022	response to hydroperoxide
GT347_08650	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GT347_08650	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GT347_08665	COG0784	Response regulator, receiver
GT347_08675	COG1914	H( )-stimulated, divalent metal cation uptake system
GT347_08685	COG0778	Nitroreductase
GT347_08690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT347_08700	COG3300	MHYT domain
GT347_08700	COG5001	Diguanylate cyclase
GT347_08720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GT347_08725	COG2916	Histone family protein nucleoid-structuring protein H-NS
GT347_08730	COG1253	flavin adenine dinucleotide binding
GT347_08735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GT347_08740	COG0513	Belongs to the DEAD box helicase family
GT347_08745	COG2321	neutral zinc metallopeptidase
GT347_08765	COG0402	S-adenosylhomocysteine deaminase activity
GT347_08775	COG0583	DNA-binding transcription factor activity
GT347_08780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GT347_08785	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_08790	COG0697	spore germination
GT347_08810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GT347_08815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GT347_08820	COG0084	hydrolase, TatD family'
GT347_08825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT347_08830	COG0714	Associated with various cellular activities
GT347_08840	COG2304	oxidoreductase activity
GT347_08845	COG5001	Diguanylate cyclase
GT347_08845	COG4251	negative regulation of phosphorylation
GT347_08845	COG3706	GGDEF domain
GT347_08845	COG2203	Gaf domain
GT347_08860	COG4191	Histidine kinase
GT347_08860	COG0784	Response regulator, receiver
GT347_08875	COG0456	acetyltransferase
GT347_08925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_08930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_08940	COG3618	amidohydrolase
GT347_08965	COG0400	carboxylic ester hydrolase activity
GT347_08970	COG3384	dioxygenase
GT347_08985	COG2814	Major facilitator Superfamily
GT347_09035	COG2186	Transcriptional regulator
GT347_09055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GT347_09060	COG1253	flavin adenine dinucleotide binding
GT347_09075	COG0442	prolyl-tRNA aminoacylation
GT347_09080	COG0494	nUDIX hydrolase
GT347_09090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GT347_09095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GT347_09100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GT347_09105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GT347_09110	COG0142	geranyltranstransferase activity
GT347_09125	COG0596	Alpha beta hydrolase
GT347_09130	COG2205	protein histidine kinase activity
GT347_09135	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GT347_09175	COG0673	inositol 2-dehydrogenase activity
GT347_09180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GT347_09185	COG0237	dephospho-CoA kinase activity
GT347_09195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GT347_09200	COG0494	nUDIX hydrolase
GT347_09210	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GT347_09215	COG0653	protein targeting
GT347_09260	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_09270	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_09290	COG3246	L-lysine catabolic process to acetate
GT347_09295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GT347_09300	COG0656	L-ascorbic acid biosynthetic process
GT347_09310	COG0583	DNA-binding transcription factor activity
GT347_09330	COG2969	positive regulation of protein catabolic process
GT347_09335	COG0625	glutathione transferase activity
GT347_09340	COG2857	Cytochrome c1
GT347_09345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GT347_09350	COG0723	plastoquinol--plastocyanin reductase activity
GT347_09355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GT347_09360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GT347_09395	COG0805	protein transport
GT347_09400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT347_09405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT347_09410	COG0537	adenosine 5'-monophosphoramidase activity
GT347_09420	COG0140	phosphoribosyl-ATP diphosphatase activity
GT347_09425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GT347_09430	COG0107	imidazoleglycerol-phosphate synthase activity
GT347_09440	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GT347_09450	COG0131	Imidazoleglycerol-phosphate dehydratase
GT347_09455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GT347_09460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GT347_09465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GT347_09470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GT347_09475	COG0271	Belongs to the BolA IbaG family
GT347_09480	COG0842	Transport permease protein
GT347_09485	COG1131	(ABC) transporter
GT347_09495	COG2854	intermembrane phospholipid transfer
GT347_09505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT347_09510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GT347_09515	COG1127	ABC transporter
GT347_09525	COG0069	glutamate synthase activity
GT347_09525	COG0070	glutamate synthase
GT347_09525	COG0067	glutamate synthase
GT347_09560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GT347_09565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GT347_09570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GT347_09610	COG1965	Belongs to the frataxin family
GT347_09630	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GT347_09640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GT347_09645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT347_09650	COG1333	cytochrome c biogenesis protein
GT347_09660	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GT347_09680	COG1560	Kdo2-lipid A biosynthetic process
GT347_09685	COG1560	Kdo2-lipid A biosynthetic process
GT347_09690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GT347_09720	COG2814	Major facilitator Superfamily
GT347_09725	COG0583	DNA-binding transcription factor activity
GT347_09740	COG1742	UPF0060 membrane protein
GT347_09745	COG0840	transmembrane signaling receptor activity
GT347_09750	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GT347_09765	COG2203	Gaf domain
GT347_09765	COG3706	GGDEF domain
GT347_09765	COG4251	negative regulation of phosphorylation
GT347_09765	COG5001	Diguanylate cyclase
GT347_09770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GT347_09775	COG0459	protein refolding
GT347_09780	COG0166	Belongs to the GPI family
GT347_09785	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GT347_09790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GT347_09850	COG0540	Belongs to the ATCase OTCase family
GT347_09855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GT347_09860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GT347_09865	COG1678	Uncharacterized ACR, COG1678
GT347_09870	COG0415	Belongs to the DNA photolyase family
GT347_09905	COG1773	rubredoxin
GT347_09915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GT347_09920	COG4772	TonB-dependent receptor
GT347_09930	COG3284	Transcriptional regulator
GT347_09935	COG0138	bifunctional purine biosynthesis protein purh
GT347_09940	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GT347_09950	COG1238	metal cluster binding
GT347_09965	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GT347_09975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GT347_09980	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GT347_10095	COG0583	DNA-binding transcription factor activity
GT347_10130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GT347_10135	COG0583	DNA-binding transcription factor activity
GT347_10145	COG5383	Protein conserved in bacteria
GT347_10150	COG0583	DNA-binding transcription factor activity
GT347_10155	COG2186	Transcriptional regulator
GT347_10170	COG0747	negative chemotaxis
GT347_10180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_10185	COG4608	Belongs to the ABC transporter superfamily
GT347_10190	COG0444	Belongs to the ABC transporter superfamily
GT347_10200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT347_10210	COG1473	amidohydrolase
GT347_10235	COG1566	PFAM secretion protein HlyD family protein
GT347_10260	COG2375	cellular response to nickel ion
GT347_10280	COG0671	phosphoesterase, PA-phosphatase related
GT347_10295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_10310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_10320	COG0688	phosphatidylethanolamine metabolic process
GT347_10335	COG0583	DNA-binding transcription factor activity
GT347_10365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_10370	COG0384	phenazine biosynthesis protein PhzF
GT347_10375	COG0625	glutathione transferase activity
GT347_10380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_10390	COG4774	siderophore transport
GT347_10400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_10405	COG0601	transmembrane transport
GT347_10410	COG0747	negative chemotaxis
GT347_10415	COG4172	Belongs to the ABC transporter superfamily
GT347_10425	COG1414	Transcriptional regulator
GT347_10430	COG1012	belongs to the aldehyde dehydrogenase family
GT347_10445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT347_10460	COG0765	amino acid transport
GT347_10465	COG0765	amino acid transport
GT347_10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_10480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_10485	COG0277	FAD linked oxidase domain protein
GT347_10495	COG0010	Belongs to the arginase family
GT347_10500	COG2814	Major facilitator Superfamily
GT347_10515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_10525	COG2084	Dehydrogenase
GT347_10535	COG0210	DNA helicase
GT347_10550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GT347_10590	COG2337	Toxic component of a toxin-antitoxin (TA) module
GT347_10595	COG0037	tRNA processing
GT347_10615	COG2255	four-way junction helicase activity
GT347_10635	COG0632	four-way junction helicase activity
GT347_10640	COG1702	phosphate starvation-inducible protein PhoH
GT347_10645	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GT347_10650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GT347_10655	COG1490	D-aminoacyl-tRNA deacylase activity
GT347_10665	COG0583	DNA-binding transcription factor activity
GT347_10680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GT347_10695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GT347_10700	COG1131	(ABC) transporter
GT347_10705	COG0842	Transport permease protein
GT347_10710	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_10720	COG0277	FAD linked oxidase domain protein
GT347_10725	COG2271	Major facilitator Superfamily
GT347_10730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT347_10735	COG4628	conserved protein (DUF2132)
GT347_10740	COG0326	Molecular chaperone. Has ATPase activity
GT347_10745	COG1187	pseudouridine synthase activity
GT347_10760	COG0165	Argininosuccinate lyase
GT347_10775	COG1914	H( )-stimulated, divalent metal cation uptake system
GT347_10780	COG0405	Gamma-glutamyltransferase
GT347_10805	COG0509	glycine decarboxylation via glycine cleavage system
GT347_10810	COG0235	Class ii aldolase
GT347_10820	COG0384	phenazine biosynthesis protein PhzF
GT347_10835	COG0012	GTP binding
GT347_10840	COG0438	transferase activity, transferring glycosyl groups
GT347_10840	COG0297	glycogen (starch) synthase activity
GT347_10845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_10855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT347_10860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT347_10915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_10930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_10935	COG1686	Belongs to the peptidase S11 family
GT347_10945	COG0473	3-isopropylmalate dehydrogenase activity
GT347_10980	COG2159	amidohydrolase
GT347_10990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GT347_11005	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_11010	COG3384	dioxygenase
GT347_11015	COG0583	DNA-binding transcription factor activity
GT347_11060	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_11065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_11075	COG0583	DNA-binding transcription factor activity
GT347_11080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_11085	COG0583	DNA-binding transcription factor activity
GT347_11100	COG0583	DNA-binding transcription factor activity
GT347_11130	COG2814	Major facilitator Superfamily
GT347_11140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_11155	COG4172	Belongs to the ABC transporter superfamily
GT347_11185	COG0583	DNA-binding transcription factor activity
GT347_11190	COG1414	Transcriptional regulator
GT347_11200	COG1012	belongs to the aldehyde dehydrogenase family
GT347_11210	COG0667	Aldo Keto reductase
GT347_11240	COG1177	transmembrane transport
GT347_11245	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_11270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_11275	COG2072	flavoprotein involved in K transport
GT347_11280	COG3842	ATPase activity
GT347_11285	COG0604	alcohol dehydrogenase
GT347_11285	COG4221	oxidoreductase activity
GT347_11285	COG3321	synthase
GT347_11285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GT347_11300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_11305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT347_11360	COG0583	DNA-binding transcription factor activity
GT347_11385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_11390	COG0436	Aminotransferase
GT347_11400	COG0765	amino acid transport
GT347_11420	COG0583	DNA-binding transcription factor activity
GT347_11445	COG0583	DNA-binding transcription factor activity
GT347_11450	COG0436	Aminotransferase
GT347_11460	COG0437	4 iron, 4 sulfur cluster binding
GT347_11465	COG2864	formate dehydrogenase
GT347_11495	COG1609	Transcriptional regulator
GT347_11515	COG2801	Transposase and inactivated derivatives
GT347_11515	COG3415	Transposase
GT347_11520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_11525	COG1335	isochorismatase
GT347_11530	COG0251	oxidation-reduction process
GT347_11535	COG2267	carboxylic ester hydrolase activity
GT347_11540	COG0778	Nitroreductase
GT347_11545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_11550	COG3971	2-oxopent-4-enoate hydratase activity
GT347_11555	COG0179	Fumarylacetoacetate (FAA) hydrolase
GT347_11565	COG0251	oxidation-reduction process
GT347_11575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_11580	COG1414	Transcriptional regulator
GT347_11620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GT347_11630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT347_11635	COG0736	holo-[acyl-carrier-protein] synthase activity
GT347_11640	COG1802	Transcriptional regulator
GT347_11645	COG2423	ornithine cyclodeaminase activity
GT347_11670	COG1012	belongs to the aldehyde dehydrogenase family
GT347_11685	COG3069	C4-dicarboxylate transmembrane transporter activity
GT347_11695	COG0154	amidase activity
GT347_11725	COG2814	Major facilitator Superfamily
GT347_11735	COG1609	Transcriptional regulator
GT347_11745	COG1846	Transcriptional regulator
GT347_11750	COG1764	response to oxidative stress
GT347_11760	COG0025	NhaP-type Na H and K H
GT347_11780	COG0642	Histidine kinase
GT347_11790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_11810	COG2204	response regulator
GT347_11815	COG5000	phosphorelay sensor kinase activity
GT347_11835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GT347_11840	COG0085	RNA polymerase activity
GT347_11845	COG0222	ribosome binding
GT347_11850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GT347_11855	COG0081	regulation of translation
GT347_11860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GT347_11880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GT347_11905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GT347_11910	COG0134	indole-3-glycerol-phosphate synthase activity
GT347_11915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GT347_11930	COG0546	phosphoglycolate phosphatase activity
GT347_11950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GT347_11955	COG2967	ApaG domain
GT347_11965	COG2199	diguanylate cyclase activity
GT347_11980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GT347_11985	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_12005	COG4335	DNA alkylation repair
GT347_12015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GT347_12030	COG0653	protein targeting
GT347_12035	COG0069	glutamate synthase activity
GT347_12050	COG1802	Transcriptional regulator
GT347_12065	COG3395	kinase activity
GT347_12070	COG0235	Class ii aldolase
GT347_12085	COG2814	Major facilitator Superfamily
GT347_12095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GT347_12120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GT347_12125	COG1137	ATPase activity
GT347_12130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GT347_12135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT347_12145	COG0018	arginyl-trna synthetase
GT347_12160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GT347_12170	COG1942	4-Oxalocrotonate Tautomerase
GT347_12175	COG0121	glutamine amidotransferase
GT347_12205	COG0189	ligase activity
GT347_12210	COG3135	benzoate transporter
GT347_12215	COG3158	transport of potassium into the cell
GT347_12225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GT347_12240	COG0495	leucyl-tRNA aminoacylation
GT347_12255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GT347_12260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT347_12265	COG0735	belongs to the Fur family
GT347_12270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GT347_12280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GT347_12285	COG0598	Magnesium transport protein CorA
GT347_12290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GT347_12295	COG0318	PFAM AMP-dependent synthetase and ligase
GT347_12310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT347_12315	COG1862	Preprotein translocase
GT347_12365	COG0583	DNA-binding transcription factor activity
GT347_12370	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_12375	COG1794	racemase activity, acting on amino acids and derivatives
GT347_12385	COG2885	chlorophyll binding
GT347_12405	COG3188	usher protein
GT347_12425	COG0469	pyruvate kinase activity
GT347_12430	COG0405	Gamma-glutamyltransferase
GT347_12435	COG0126	phosphoglycerate kinase activity
GT347_12455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GT347_12465	COG0242	peptide deformylase activity
GT347_12475	COG0758	DNA mediated transformation
GT347_12485	COG0629	single-stranded DNA binding
GT347_12490	COG0513	Belongs to the DEAD box helicase family
GT347_12510	COG5001	Diguanylate cyclase
GT347_12525	COG0482	sulfurtransferase activity
GT347_12530	COG0583	DNA-binding transcription factor activity
GT347_12535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_12540	COG3799	methylaspartate ammonia-lyase activity
GT347_12550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_12570	COG0840	transmembrane signaling receptor activity
GT347_12590	COG0235	Class ii aldolase
GT347_12595	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_12610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_12615	COG2814	Major facilitator Superfamily
GT347_12620	COG3706	GGDEF domain
GT347_12635	COG2814	Major facilitator Superfamily
GT347_12655	COG2186	Transcriptional regulator
GT347_12665	COG2423	ornithine cyclodeaminase activity
GT347_12680	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GT347_12700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_12710	COG4566	intracellular signal transduction
GT347_12735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GT347_12740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GT347_12765	COG3550	peptidyl-serine autophosphorylation
GT347_12775	COG1410	methionine synthase
GT347_12775	COG0646	methionine synthase
GT347_12785	COG3550	peptidyl-serine autophosphorylation
GT347_12790	COG1047	Peptidyl-prolyl cis-trans
GT347_12795	COG0023	Translation Initiation Factor
GT347_12810	COG3267	Type II secretory pathway component ExeA
GT347_12810	COG3409	Peptidoglycan-binding domain 1 protein
GT347_12830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GT347_12835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GT347_12855	COG0006	proline dipeptidase activity
GT347_12870	COG2814	Major facilitator Superfamily
GT347_12875	COG0737	Belongs to the 5'-nucleotidase family
GT347_12895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GT347_12900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_12905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT347_12915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GT347_12935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT347_12940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GT347_12950	COG0300	oxidoreductase activity
GT347_12980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GT347_12985	COG0706	membrane insertase activity
GT347_12990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GT347_12995	COG0594	ribonuclease P activity
GT347_13000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GT347_13005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GT347_13010	COG0592	DNA-directed DNA polymerase activity
GT347_13055	COG1064	alcohol dehydrogenase
GT347_13065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GT347_13075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT347_13080	COG1012	belongs to the aldehyde dehydrogenase family
GT347_13090	COG2608	mercury ion transmembrane transporter activity
GT347_13095	COG2974	May be involved in recombination
GT347_13115	COG3568	Endonuclease Exonuclease Phosphatase
GT347_13120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT347_13125	COG0392	lysyltransferase activity
GT347_13135	COG1573	uracil-dna glycosylase
GT347_13150	COG0583	DNA-binding transcription factor activity
GT347_13155	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_13160	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_13165	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_13170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GT347_13175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_13180	COG0583	DNA-binding transcription factor activity
GT347_13185	COG1396	sequence-specific DNA binding
GT347_13195	COG1408	metallophosphoesterase
GT347_13200	COG2814	Major facilitator Superfamily
GT347_13220	COG2217	Heavy metal translocating P-type atpase
GT347_13225	COG0840	transmembrane signaling receptor activity
GT347_13235	COG0583	DNA-binding transcription factor activity
GT347_13240	COG0277	FAD linked oxidase domain protein
GT347_13250	COG2205	protein histidine kinase activity
GT347_13250	COG2198	Histidine kinase
GT347_13250	COG0784	Response regulator, receiver
GT347_13260	COG5001	Diguanylate cyclase
GT347_13260	COG3300	MHYT domain
GT347_13280	COG1475	DNA binding
GT347_13290	COG1192	Involved in chromosome partitioning
GT347_13295	COG0357	Ribosomal RNA small subunit methyltransferase G
GT347_13330	COG0625	glutathione transferase activity
GT347_13335	COG4178	(ABC) transporter
GT347_13340	COG1902	pentaerythritol trinitrate reductase activity
GT347_13395	COG0625	glutathione transferase activity
GT347_13400	COG1609	Transcriptional regulator
GT347_13405	COG1609	Transcriptional regulator
GT347_13410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_13415	COG1022	Amp-dependent synthetase and ligase
GT347_13460	COG0850	regulation of cytokinetic process
GT347_13470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GT347_13485	COG0284	orotidine-5'-phosphate decarboxylase activity
GT347_13505	COG2027	D-alanyl-D-alanine carboxypeptidase
GT347_13515	COG0009	L-threonylcarbamoyladenylate synthase
GT347_13520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GT347_13525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GT347_13530	COG3118	belongs to the thioredoxin family
GT347_13535	COG1902	pentaerythritol trinitrate reductase activity
GT347_13565	COG0457	Tetratricopeptide repeat
GT347_13570	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GT347_13575	COG0457	Tetratricopeptide repeat
GT347_13580	COG1215	transferase activity, transferring glycosyl groups
GT347_13585	COG1215	transferase activity, transferring glycosyl groups
GT347_13605	COG2814	Major facilitator Superfamily
GT347_13635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GT347_13640	COG2801	Transposase and inactivated derivatives
GT347_13640	COG3415	Transposase
GT347_13660	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GT347_13660	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GT347_13680	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_13690	COG0642	Histidine kinase
GT347_13705	COG5001	Diguanylate cyclase
GT347_13705	COG4251	negative regulation of phosphorylation
GT347_13705	COG3706	GGDEF domain
GT347_13705	COG2203	Gaf domain
GT347_13715	COG0154	amidase activity
GT347_13725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GT347_13735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GT347_13740	COG2137	regulation of response to DNA damage stimulus
GT347_13750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_13755	COG4166	transmembrane transport
GT347_13760	COG4172	Belongs to the ABC transporter superfamily
GT347_13795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_13795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_13805	COG1764	response to oxidative stress
GT347_13820	COG1522	sequence-specific DNA binding
GT347_13840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GT347_13875	COG2094	Belongs to the DNA glycosylase MPG family
GT347_13880	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_13900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GT347_13905	COG0045	succinate-CoA ligase (ADP-forming) activity
GT347_13910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GT347_13915	COG0861	Integral membrane protein TerC family
GT347_13920	COG0631	protein serine/threonine phosphatase activity
GT347_13925	COG1716	ATPase activity
GT347_13940	COG4969	Belongs to the N-Me-Phe pilin family
GT347_13970	COG1950	PFAM Membrane protein of
GT347_13980	COG0861	Integral membrane protein TerC family
GT347_14000	COG0625	glutathione transferase activity
GT347_14005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT347_14060	COG0583	DNA-binding transcription factor activity
GT347_14075	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_14080	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_14095	COG0347	Belongs to the P(II) protein family
GT347_14100	COG0004	ammonium transporteR
GT347_14110	COG0277	FAD linked oxidase domain protein
GT347_14120	COG0247	lactate metabolic process
GT347_14135	COG0477	Major facilitator Superfamily
GT347_14145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT347_14155	COG0700	Nucleoside recognition
GT347_14230	COG0745	RESPONSE REGULATOR receiver
GT347_14270	COG0708	Exodeoxyribonuclease III
GT347_14275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GT347_14300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GT347_14305	COG0154	amidase activity
GT347_14310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GT347_14315	COG1077	Cell shape determining protein MreB Mrl
GT347_14320	COG1792	Involved in formation and maintenance of cell shape
GT347_14330	COG0768	penicillin binding
GT347_14340	COG0004	ammonium transporteR
GT347_14350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GT347_14355	COG1127	ABC transporter
GT347_14370	COG0412	Dienelactone hydrolase
GT347_14375	COG0598	Magnesium transport protein CorA
GT347_14395	COG3411	Ferredoxin
GT347_14400	COG2945	thiolester hydrolase activity
GT347_14405	COG1686	Belongs to the peptidase S11 family
GT347_14410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GT347_14415	COG0049	tRNA binding
GT347_14420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GT347_14425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GT347_14430	COG0051	transcription antitermination factor activity, RNA binding
GT347_14435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GT347_14440	COG0088	Forms part of the polypeptide exit tunnel
GT347_14445	COG0089	rRNA binding
GT347_14450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GT347_14455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GT347_14460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GT347_14465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GT347_14470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GT347_14475	COG0255	Belongs to the universal ribosomal protein uL29 family
GT347_14480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GT347_14485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT347_14485	COG0678	peroxiredoxin activity
GT347_14510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT347_14515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GT347_14525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GT347_14530	COG0321	lipoyl(octanoyl) transferase activity
GT347_14535	COG2921	Belongs to the UPF0250 family
GT347_14550	COG0356	it plays a direct role in the translocation of protons across the membrane
GT347_14560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GT347_14565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GT347_14570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GT347_14575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GT347_14580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GT347_14585	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GT347_14595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GT347_14595	COG1793	dna ligase
GT347_14600	COG1793	dna ligase
GT347_14610	COG1201	RNA secondary structure unwinding
GT347_14660	COG0438	transferase activity, transferring glycosyl groups
GT347_14665	COG3245	cytochrome
GT347_14675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT347_14680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_14695	COG0583	DNA-binding transcription factor activity
GT347_14740	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_14745	COG0583	DNA-binding transcription factor activity
GT347_14760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT347_14765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_14810	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT347_14810	COG2918	glutathione biosynthetic process
GT347_14955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GT347_14970	COG1157	protein secretion by the type III secretion system
GT347_14990	COG1677	Flagellar hook-basal body complex protein FliE
GT347_15000	COG1815	bacterial-type flagellum-dependent cell motility
GT347_15005	COG1706	bacterial-type flagellum-dependent cell motility
GT347_15010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT347_15025	COG4786	Flagellar basal body rod
GT347_15030	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_15040	COG1684	flagellar biosynthetic protein fliR
GT347_15045	COG1987	bacterial-type flagellum assembly
GT347_15130	COG0343	queuine tRNA-ribosyltransferase activity
GT347_15145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GT347_15160	COG0783	Belongs to the Dps family
GT347_15165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GT347_15175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT347_15185	COG3842	ATPase activity
GT347_15200	COG0395	ABC-type sugar transport system, permease component
GT347_15215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GT347_15220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GT347_15225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GT347_15230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GT347_15235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GT347_15240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GT347_15245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GT347_15250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GT347_15260	COG1841	ribosomal large subunit assembly
GT347_15265	COG0200	Binds to the 23S rRNA
GT347_15275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GT347_15280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GT347_15285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GT347_15290	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GT347_15295	COG0202	RNA polymerase activity
GT347_15300	COG0203	ribosomal protein L17
GT347_15310	COG1802	Transcriptional regulator
GT347_15320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_15325	COG0251	oxidation-reduction process
GT347_15330	COG0235	Class ii aldolase
GT347_15345	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_15350	COG1396	sequence-specific DNA binding
GT347_15365	COG0725	ABC transporter, periplasmic molybdate-binding protein
GT347_15370	COG4149	molybdate abc transporter
GT347_15375	COG1971	Probably functions as a manganese efflux pump
GT347_15410	COG1254	Belongs to the acylphosphatase family
GT347_15430	COG0420	3'-5' exonuclease activity
GT347_15440	COG3415	Transposase
GT347_15440	COG2801	Transposase and inactivated derivatives
GT347_15445	COG1309	transcriptional regulator
GT347_15465	COG1129	ABC transporter
GT347_15505	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_15510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GT347_15515	COG1724	mRNA binding
GT347_15520	COG1598	PFAM Uncharacterised protein family UPF0150
GT347_15540	COG2080	2 iron, 2 sulfur cluster binding
GT347_15545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GT347_15550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_15555	COG0028	Belongs to the TPP enzyme family
GT347_15575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_15585	COG3415	Transposase
GT347_15585	COG2801	Transposase and inactivated derivatives
GT347_15590	COG3415	Transposase
GT347_15590	COG2801	Transposase and inactivated derivatives
GT347_15595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_15605	COG0752	glycyl-tRNA synthetase alpha subunit
GT347_15610	COG0751	glycine-tRNA ligase activity
GT347_15615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GT347_15650	COG0288	reversible hydration of carbon dioxide
GT347_15655	COG0183	Belongs to the thiolase family
GT347_15660	COG3210	domain, Protein
GT347_15670	COG1902	pentaerythritol trinitrate reductase activity
GT347_15675	COG3012	SEC-C Motif Domain Protein
GT347_15685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_15695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GT347_15715	COG0351	phosphomethylpyrimidine kinase
GT347_15760	COG1960	acyl-CoA dehydrogenase activity
GT347_15765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GT347_15770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GT347_15880	COG0477	Major facilitator Superfamily
GT347_15890	COG0583	DNA-binding transcription factor activity
GT347_15895	COG1902	pentaerythritol trinitrate reductase activity
GT347_15900	COG2132	Multicopper oxidase
GT347_15910	COG2372	response to copper ion
GT347_15950	COG1475	DNA binding
GT347_16040	COG1802	Transcriptional regulator
GT347_16040	COG4626	Terminase
GT347_16160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT347_16165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT347_16215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT347_16245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GT347_16250	COG0183	Belongs to the thiolase family
GT347_16255	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_16280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GT347_16290	COG1040	competence protein
GT347_16295	COG2226	methyltransferase
GT347_16315	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GT347_16345	COG1612	heme a metabolic process
GT347_16350	COG0109	protoheme IX farnesyltransferase activity
GT347_16355	COG1999	signal sequence binding
GT347_16365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GT347_16375	COG0612	Peptidase, M16
GT347_16390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GT347_16435	COG2197	response regulator
GT347_16450	COG2982	Protein involved in outer membrane biogenesis
GT347_16460	COG0793	Belongs to the peptidase S41A family
GT347_16465	COG0588	phosphoglycerate mutase activity
GT347_16470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT347_16475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT347_16480	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GT347_16485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GT347_16490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GT347_16495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GT347_16505	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GT347_16510	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GT347_16520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GT347_16530	COG1194	a g-specific adenine glycosylase
GT347_16535	COG1660	Displays ATPase and GTPase activities
GT347_16540	COG0497	DNA recombination
GT347_16545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GT347_16550	COG1420	regulation of RNA biosynthetic process
GT347_16565	COG1024	Enoyl-CoA hydratase
GT347_16575	COG1024	Enoyl-CoA hydratase
GT347_16580	COG1960	acyl-CoA dehydrogenase activity
GT347_16585	COG3180	Ammonia monooxygenase
GT347_16610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_16620	COG0436	Aminotransferase
GT347_16630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_16635	COG0765	amino acid transport
GT347_16640	COG1126	abc transporter atp-binding protein
GT347_16645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_16655	COG0006	proline dipeptidase activity
GT347_16670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_16685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_16690	COG0601	transmembrane transport
GT347_16695	COG0747	negative chemotaxis
GT347_16705	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_16710	COG3842	ATPase activity
GT347_16720	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_16725	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GT347_16730	COG1984	allophanate hydrolase subunit 2
GT347_16735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GT347_16740	COG0436	Aminotransferase
GT347_16790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_16795	COG1802	Transcriptional regulator
GT347_16820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_16820	COG2010	Cytochrome c
GT347_16825	COG2080	2 iron, 2 sulfur cluster binding
GT347_16830	COG1335	isochorismatase
GT347_16855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT347_16875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT347_16885	COG1126	abc transporter atp-binding protein
GT347_16900	COG0765	amino acid transport
GT347_16930	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_16940	COG0697	spore germination
GT347_16950	COG0243	molybdopterin cofactor binding
GT347_16955	COG2916	Histone family protein nucleoid-structuring protein H-NS
GT347_16980	COG2205	protein histidine kinase activity
GT347_16985	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GT347_17000	COG0588	phosphoglycerate mutase activity
GT347_17005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GT347_17010	COG2084	Dehydrogenase
GT347_17055	COG1802	Transcriptional regulator
GT347_17060	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_17095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_17110	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GT347_17115	COG3387	PFAM Glycoside hydrolase 15-related
GT347_17125	COG1877	trehalose-phosphatase activity
GT347_17135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_17145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT347_17155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GT347_17155	COG5297	Belongs to the glycosyl hydrolase family 6
GT347_17170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GT347_17195	COG0617	tRNA 3'-terminal CCA addition
GT347_17200	COG3279	Response regulator of the LytR AlgR family
GT347_17205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GT347_17210	COG0739	heme binding
GT347_17210	COG1196	nuclear chromosome segregation
GT347_17210	COG0741	lytic transglycosylase activity
GT347_17235	COG4535	Mg2 and Co2 transporter CorC
GT347_17240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GT347_17255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GT347_17270	COG0829	nickel cation binding
GT347_17280	COG0831	urea catabolic process
GT347_17290	COG0832	Belongs to the urease beta subunit family
GT347_17295	COG0804	urea catabolic process
GT347_17310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GT347_17315	COG0830	nickel cation binding
GT347_17320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GT347_17340	COG2076	Multidrug Resistance protein
GT347_17375	COG0745	RESPONSE REGULATOR receiver
GT347_17380	COG2205	protein histidine kinase activity
GT347_17400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GT347_17435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GT347_17440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GT347_17445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GT347_17470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GT347_17475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GT347_17480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GT347_17485	COG0316	Belongs to the HesB IscA family
GT347_17490	COG0477	Major facilitator Superfamily
GT347_17495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GT347_17500	COG0739	heme binding
GT347_17505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GT347_17510	COG0583	DNA-binding transcription factor activity
GT347_17540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GT347_17545	COG4251	negative regulation of phosphorylation
GT347_17610	COG4770	biotin carboxylase activity
GT347_17615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GT347_17635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GT347_17640	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GT347_17675	COG0765	amino acid transport
GT347_17685	COG4774	siderophore transport
GT347_17695	COG2188	Transcriptional regulator
GT347_17705	COG0066	3-isopropylmalate dehydratase activity
GT347_17710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_17730	COG4608	Belongs to the ABC transporter superfamily
GT347_17735	COG0444	Belongs to the ABC transporter superfamily
GT347_17740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_17745	COG0601	transmembrane transport
GT347_17750	COG0747	negative chemotaxis
GT347_17770	COG0778	Nitroreductase
GT347_17780	COG2197	response regulator
GT347_17785	COG4585	Histidine kinase
GT347_17805	COG3550	peptidyl-serine autophosphorylation
GT347_17815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_17825	COG1414	Transcriptional regulator
GT347_17830	COG0583	DNA-binding transcription factor activity
GT347_17840	COG1012	belongs to the aldehyde dehydrogenase family
GT347_17855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_17870	COG0405	Gamma-glutamyltransferase
GT347_17880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_17920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GT347_17925	COG2146	nitrite reductase [NAD(P)H] activity
GT347_17930	COG0446	pyridine nucleotide-disulphide oxidoreductase
GT347_17955	COG3473	Maleate cis-trans isomerase
GT347_17960	COG0596	Alpha beta hydrolase
GT347_17965	COG2309	aminopeptidase activity
GT347_17970	COG1335	isochorismatase
GT347_17995	COG5002	protein histidine kinase activity
GT347_17995	COG5001	Diguanylate cyclase
GT347_18000	COG0583	DNA-binding transcription factor activity
GT347_18015	COG0583	DNA-binding transcription factor activity
GT347_18020	COG4336	lyase activity
GT347_18030	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_18055	COG0583	DNA-binding transcription factor activity
GT347_18060	COG0405	Gamma-glutamyltransferase
GT347_18065	COG4178	(ABC) transporter
GT347_18085	COG3842	ATPase activity
GT347_18090	COG1609	Transcriptional regulator
GT347_18095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GT347_18145	COG2847	Copper chaperone PCu(A)C
GT347_18160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GT347_18170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GT347_18180	COG0523	cobalamin synthesis protein
GT347_18195	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GT347_18200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GT347_18205	COG2001	Belongs to the MraZ family
GT347_18210	COG0275	rRNA processing
GT347_18225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GT347_18230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GT347_18235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT347_18240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GT347_18245	COG0772	Belongs to the SEDS family
GT347_18255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT347_18260	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT347_18265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GT347_18275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GT347_18290	COG3177	Filamentation induced by cAMP protein fic
GT347_18310	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GT347_18345	COG0347	Belongs to the P(II) protein family
GT347_18355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_18370	COG2205	protein histidine kinase activity
GT347_18370	COG0784	Response regulator, receiver
GT347_18450	COG2814	Major facilitator Superfamily
GT347_18455	COG1639	'signal transduction protein
GT347_18465	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GT347_18510	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GT347_18520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT347_18525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT347_18540	COG3150	esterase
GT347_18555	COG0772	Belongs to the SEDS family
GT347_18565	COG0312	modulator of DNA gyrase
GT347_18585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT347_18590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT347_18600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GT347_18605	COG0511	ligase activity, forming carbon-carbon bonds
GT347_18610	COG0439	Biotin carboxylase
GT347_18615	COG2264	protein methyltransferase activity
GT347_18625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT347_18635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT347_18640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT347_18640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT347_18670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GT347_18675	COG2943	transferase activity, transferring hexosyl groups
GT347_18680	COG2204	response regulator
GT347_18695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT347_18730	COG2197	response regulator
GT347_18735	COG1116	anion transmembrane transporter activity
GT347_18735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_18740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_18745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_18745	COG1116	anion transmembrane transporter activity
GT347_18750	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GT347_18795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_18835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_18870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_18875	COG0154	amidase activity
GT347_18885	COG3657	addiction module killer protein
GT347_18905	COG0280	phosphate acetyltransferase
GT347_18905	COG0281	malic enzyme
GT347_18920	COG3206	protein involved in exopolysaccharide biosynthesis
GT347_18920	COG0489	protein tyrosine kinase activity
GT347_18960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GT347_18965	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GT347_18980	COG2346	COG2346, Truncated hemoglobins
GT347_18985	COG1193	negative regulation of DNA recombination
GT347_18990	COG2003	Belongs to the UPF0758 family
GT347_18995	COG1047	Peptidyl-prolyl cis-trans
GT347_19010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GT347_19030	COG1063	alcohol dehydrogenase
GT347_19035	COG1295	ribonuclease BN
GT347_19045	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_19050	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GT347_19055	COG0066	3-isopropylmalate dehydratase activity
GT347_19060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_19065	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_19120	COG2186	Transcriptional regulator
GT347_19125	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_19130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_19140	COG1366	Belongs to the anti-sigma-factor antagonist family
GT347_19145	COG1366	Belongs to the anti-sigma-factor antagonist family
GT347_19150	COG2172	sigma factor antagonist activity
GT347_19160	COG2205	protein histidine kinase activity
GT347_19165	COG2205	protein histidine kinase activity
GT347_19165	COG0784	Response regulator, receiver
GT347_19170	COG2205	protein histidine kinase activity
GT347_19170	COG0784	Response regulator, receiver
GT347_19170	COG2198	Histidine kinase
GT347_19175	COG0784	Response regulator, receiver
GT347_19180	COG4251	negative regulation of phosphorylation
GT347_19185	COG1064	alcohol dehydrogenase
GT347_19195	COG0791	NLP P60 protein
GT347_19215	COG1611	Belongs to the LOG family
GT347_19250	COG2059	Chromate
GT347_19255	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GT347_19270	COG3706	GGDEF domain
GT347_19270	COG4251	negative regulation of phosphorylation
GT347_19270	COG2203	Gaf domain
GT347_19270	COG5001	Diguanylate cyclase
GT347_19275	COG0154	amidase activity
GT347_19295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT347_19300	COG0277	FAD linked oxidase domain protein
GT347_19310	COG1295	ribonuclease BN
GT347_19320	COG0516	GMP reductase activity
GT347_19320	COG0517	IMP dehydrogenase activity
GT347_19335	COG1320	monovalent cation:proton antiporter activity
GT347_19340	COG2212	antiporter activity
GT347_19345	COG1863	multisubunit Na H antiporter MnhE subunit
GT347_19350	COG0651	ATP synthesis coupled electron transport
GT347_19355	COG1006	Multisubunit Na H antiporter MnhC subunit
GT347_19360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GT347_19360	COG2111	Na H antiporter
GT347_19375	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GT347_19385	COG0776	regulation of translation
GT347_19395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GT347_19400	COG0287	Prephenate dehydrogenase
GT347_19410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GT347_19425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT347_19440	COG1187	pseudouridine synthase activity
GT347_19465	COG0174	glutamine synthetase
GT347_19475	COG3852	Histidine kinase
GT347_19485	COG0708	Exodeoxyribonuclease III
GT347_19505	COG1216	Glycosyl transferase, family 2
GT347_19510	COG1045	serine acetyltransferase
GT347_19585	COG2197	response regulator
GT347_19590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GT347_19600	COG5002	protein histidine kinase activity
GT347_19600	COG0784	Response regulator, receiver
GT347_19600	COG2198	Histidine kinase
GT347_19625	COG2207	Transcriptional regulator
GT347_19650	COG4794	Type iii secretion
GT347_19730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_19740	COG1450	Type ii and iii secretion system protein
GT347_19750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GT347_19755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GT347_19765	COG2808	Putative FMN-binding domain
GT347_19770	COG1609	Transcriptional regulator
GT347_19780	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GT347_19785	COG1289	transmembrane transporter activity
GT347_19790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT347_19795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT347_19800	COG0741	lytic transglycosylase activity
GT347_19815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GT347_19840	COG0688	phosphatidylethanolamine metabolic process
GT347_19855	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_19860	COG2072	flavoprotein involved in K transport
GT347_19865	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_19875	COG4172	Belongs to the ABC transporter superfamily
GT347_19880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_19885	COG0601	transmembrane transport
GT347_19890	COG0747	negative chemotaxis
GT347_19900	COG0322	excinuclease ABC activity
GT347_19920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_19930	COG3437	response regulator, receiver
GT347_19955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GT347_19960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GT347_19985	COG0583	DNA-binding transcription factor activity
GT347_19990	COG1960	acyl-CoA dehydrogenase activity
GT347_19995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_20005	COG1295	ribonuclease BN
GT347_20005	COG1959	2 iron, 2 sulfur cluster binding
GT347_20040	COG0683	leucine binding
GT347_20440	COG0425	Belongs to the sulfur carrier protein TusA family
GT347_20445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GT347_20475	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GT347_20490	COG0477	Major facilitator Superfamily
GT347_20500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GT347_20505	COG0358	DNA primase activity
GT347_20510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GT347_20535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GT347_20555	COG3959	Transketolase, thiamine diphosphate binding domain
GT347_20560	COG3958	Transketolase
GT347_20575	COG1442	glycosyl transferase family 8
GT347_20575	COG1216	Glycosyl transferase, family 2
GT347_20625	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT347_20640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GT347_20655	COG3540	Alkaline phosphatase
GT347_20680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_20685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT347_20690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GT347_20695	COG4988	ABC transporter
GT347_20705	COG1294	oxidase, subunit
GT347_20715	COG3047	cAMP biosynthetic process
GT347_20730	COG0583	DNA-binding transcription factor activity
GT347_20735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_20745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GT347_20755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_20760	COG1960	acyl-CoA dehydrogenase activity
GT347_20780	COG1301	dicarboxylic acid transport
GT347_20810	COG3618	amidohydrolase
GT347_20815	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_20835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_20850	COG4172	Belongs to the ABC transporter superfamily
GT347_20855	COG1446	asparaginase
GT347_20885	COG0583	DNA-binding transcription factor activity
GT347_20905	COG2267	carboxylic ester hydrolase activity
GT347_20910	COG3706	GGDEF domain
GT347_20940	COG0583	DNA-binding transcription factor activity
GT347_20945	COG0667	Aldo Keto reductase
GT347_20960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_20970	COG0583	DNA-binding transcription factor activity
GT347_20975	COG3781	membrane
GT347_21005	COG4302	ethanolamine ammonia-lyase activity
GT347_21025	COG0583	DNA-binding transcription factor activity
GT347_21030	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_21045	COG2207	Transcriptional regulator
GT347_21050	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_21055	COG0784	Response regulator, receiver
GT347_21055	COG4191	Histidine kinase
GT347_21060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_21070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_21085	COG1129	ABC transporter
GT347_21120	COG0583	DNA-binding transcription factor activity
GT347_21135	COG1283	sodium-dependent phosphate transmembrane transporter activity
GT347_21140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GT347_21150	COG0196	riboflavin kinase activity
GT347_21160	COG3132	Protein of unknown function, DUF480
GT347_21165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GT347_21175	COG0745	RESPONSE REGULATOR receiver
GT347_21180	COG2205	protein histidine kinase activity
GT347_21185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT347_21185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GT347_21195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GT347_21200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GT347_21205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GT347_21210	COG0492	ferredoxin-NADP+ reductase activity
GT347_21220	COG1674	ftsk spoiiie
GT347_21225	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GT347_21230	COG0038	chloride channel
GT347_21240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GT347_21245	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_21270	COG1392	Phosphate transport regulator
GT347_21275	COG0306	phosphate transporter
GT347_21290	COG0228	four-way junction DNA binding
GT347_21295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GT347_21300	COG0336	Belongs to the RNA methyltransferase TrmD family
GT347_21305	COG0335	large ribosomal subunit rRNA binding
GT347_21315	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GT347_21325	COG1162	GTPase activity
GT347_21330	COG2154	pterin-4-alpha-carbinolamine dehydratase
GT347_21335	COG0501	Belongs to the peptidase M48B family
GT347_21340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GT347_21345	COG0513	Belongs to the DEAD box helicase family
GT347_21350	COG5001	Diguanylate cyclase
GT347_21350	COG3300	MHYT domain
GT347_21355	COG2814	Major facilitator Superfamily
GT347_21400	COG1595	DNA-templated transcription, initiation
GT347_21405	COG3712	iron ion homeostasis
GT347_21410	COG4774	siderophore transport
GT347_21415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_21465	COG1522	sequence-specific DNA binding
GT347_21470	COG0028	Belongs to the TPP enzyme family
GT347_21485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT347_21490	COG0583	DNA-binding transcription factor activity
GT347_21520	COG0671	phosphoesterase, PA-phosphatase related
GT347_21525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GT347_21530	COG2076	Multidrug Resistance protein
GT347_21540	COG1215	transferase activity, transferring glycosyl groups
GT347_21545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_21545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GT347_21555	COG0726	polysaccharide deacetylase
GT347_21590	COG3712	iron ion homeostasis
GT347_21600	COG0390	transport system, permease component
GT347_21605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT347_21630	COG4191	Histidine kinase
GT347_21630	COG0784	Response regulator, receiver
GT347_21640	COG0745	RESPONSE REGULATOR receiver
GT347_21645	COG0642	Histidine kinase
GT347_21650	COG5002	protein histidine kinase activity
GT347_21655	COG0745	RESPONSE REGULATOR receiver
GT347_21660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_21670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_21695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_21700	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_21710	COG1802	Transcriptional regulator
GT347_21725	COG2353	YceI-like domain
GT347_21770	COG1595	DNA-templated transcription, initiation
GT347_21785	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_21790	COG0583	DNA-binding transcription factor activity
GT347_21795	COG0583	DNA-binding transcription factor activity
GT347_21810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GT347_21870	COG1280	lysine exporter protein (LysE YggA)
GT347_21920	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_21955	COG1309	transcriptional regulator
GT347_21985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_21995	COG0747	negative chemotaxis
GT347_22010	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_22015	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_22025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_22030	COG0583	DNA-binding transcription factor activity
GT347_22060	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_22085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_22090	COG0436	Aminotransferase
GT347_22105	COG0745	RESPONSE REGULATOR receiver
GT347_22120	COG2194	sulfuric ester hydrolase activity
GT347_22170	COG3800	Transcriptional regulator
GT347_22170	COG1396	sequence-specific DNA binding
GT347_22185	COG2376	Dihydroxyacetone kinase
GT347_22190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_22225	COG3246	L-lysine catabolic process to acetate
GT347_22230	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_22235	COG0583	DNA-binding transcription factor activity
GT347_22255	COG3186	Phenylalanine-4-hydroxylase
GT347_22275	COG5002	protein histidine kinase activity
GT347_22275	COG5001	Diguanylate cyclase
GT347_22275	COG3447	MASE1 domain protein
GT347_22305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_22310	COG1024	Enoyl-CoA hydratase
GT347_22315	COG1960	acyl-CoA dehydrogenase activity
GT347_22320	COG1960	acyl-CoA dehydrogenase activity
GT347_22325	COG0183	Belongs to the thiolase family
GT347_22330	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_22330	COG1024	Enoyl-CoA hydratase
GT347_22335	COG0583	DNA-binding transcription factor activity
GT347_22365	COG0436	Aminotransferase
GT347_22405	COG0745	RESPONSE REGULATOR receiver
GT347_22420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT347_22425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT347_22435	COG0129	dihydroxy-acid dehydratase activity
GT347_22440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_22450	COG0583	DNA-binding transcription factor activity
GT347_22460	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_22470	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_22515	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_22525	COG1116	anion transmembrane transporter activity
GT347_22530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_22560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_22605	COG1858	cytochrome C peroxidase
GT347_22625	COG1024	Enoyl-CoA hydratase
GT347_22630	COG1960	acyl-CoA dehydrogenase activity
GT347_22640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_22650	COG0516	GMP reductase activity
GT347_22660	COG0210	DNA helicase
GT347_22670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GT347_22710	COG0165	Argininosuccinate lyase
GT347_22720	COG0642	Histidine kinase
GT347_22750	COG3634	alkyl hydroperoxide reductase activity
GT347_22760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GT347_22780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT347_22800	COG0193	aminoacyl-tRNA hydrolase activity
GT347_22820	COG1012	belongs to the aldehyde dehydrogenase family
GT347_22830	COG2721	sulfolactate sulfo-lyase activity
GT347_22835	COG2186	Transcriptional regulator
GT347_22840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_22845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_22855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GT347_22875	COG0489	protein tyrosine kinase activity
GT347_22915	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_22930	COG2223	nitrite transmembrane transporter activity
GT347_22935	COG0243	molybdopterin cofactor binding
GT347_22950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GT347_22985	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GT347_23000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GT347_23005	COG2890	protein-(glutamine-N5) methyltransferase activity
GT347_23010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GT347_23015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GT347_23030	COG0584	glycerophosphoryl diester phosphodiesterase
GT347_23035	COG3842	ATPase activity
GT347_23050	COG1653	transport
GT347_23055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_23065	COG3720	iron ion transport
GT347_23070	COG3733	amine oxidase
GT347_23090	COG0583	DNA-binding transcription factor activity
GT347_23105	COG4166	transmembrane transport
GT347_23115	COG3842	ATPase activity
GT347_23120	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_23125	COG1177	transmembrane transport
GT347_23140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_23155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT347_23160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT347_23165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GT347_23170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_23180	COG2267	carboxylic ester hydrolase activity
GT347_23185	COG3485	protocatechuate 3,4-dioxygenase
GT347_23190	COG3485	protocatechuate 3,4-dioxygenase
GT347_23195	COG0583	DNA-binding transcription factor activity
GT347_23215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_23230	COG0028	Belongs to the TPP enzyme family
GT347_23240	COG0477	Major facilitator Superfamily
GT347_23255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT347_23265	COG1473	amidohydrolase
GT347_23270	COG0583	DNA-binding transcription factor activity
GT347_23275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GT347_23295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GT347_23330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT347_23330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT347_23335	COG0513	Belongs to the DEAD box helicase family
GT347_23350	COG0488	(ABC) transporter
GT347_23360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GT347_23370	COG4977	sequence-specific DNA binding
GT347_23375	COG0372	Belongs to the citrate synthase family
GT347_23380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GT347_23385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GT347_23395	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GT347_23405	COG2188	Transcriptional regulator
GT347_23410	COG0039	L-malate dehydrogenase activity
GT347_23415	COG4106	trans-aconitate 2-methyltransferase activity
GT347_23445	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GT347_23465	COG0544	peptidyl-prolyl cis-trans isomerase activity
GT347_23470	COG0740	serine-type endopeptidase activity
GT347_23475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GT347_23480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GT347_23500	COG3447	MASE1 domain protein
GT347_23500	COG5001	Diguanylate cyclase
GT347_23500	COG5002	protein histidine kinase activity
GT347_23515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GT347_23525	COG1858	cytochrome C peroxidase
GT347_23540	COG1012	belongs to the aldehyde dehydrogenase family
GT347_23545	COG3284	Transcriptional regulator
GT347_23560	COG0114	fumarate hydratase activity
GT347_23570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GT347_23580	COG4654	Cytochrome c, class I
GT347_23590	COG0129	dihydroxy-acid dehydratase activity
GT347_23595	COG0583	DNA-binding transcription factor activity
GT347_23600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GT347_23605	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GT347_23615	COG0667	Aldo Keto reductase
GT347_23620	COG4999	Histidine kinase
GT347_23620	COG3850	Histidine kinase
GT347_23620	COG2205	protein histidine kinase activity
GT347_23620	COG3437	response regulator, receiver
GT347_23625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GT347_23650	COG1666	GTP binding
GT347_23655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GT347_23670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GT347_23680	COG0762	integral membrane protein
GT347_23685	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GT347_23690	COG0159	tryptophan synthase activity
GT347_23695	COG0133	tryptophan synthase activity
GT347_23700	COG0135	phosphoribosylanthranilate isomerase activity
GT347_23705	COG0101	tRNA pseudouridine synthase activity
GT347_23725	COG5001	Diguanylate cyclase
GT347_23725	COG4251	negative regulation of phosphorylation
GT347_23725	COG3706	GGDEF domain
GT347_23725	COG2203	Gaf domain
GT347_23730	COG0473	3-isopropylmalate dehydrogenase activity
GT347_23735	COG0066	3-isopropylmalate dehydratase activity
GT347_23740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_23750	COG0484	heat shock protein binding
GT347_23755	COG0443	Heat shock 70 kDa protein
GT347_23760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GT347_23765	COG0360	Binds together with S18 to 16S ribosomal RNA
GT347_23775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GT347_23780	COG0359	binds to the 23S rRNA
GT347_23785	COG0305	Participates in initiation and elongation during chromosome replication
GT347_23800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT347_23810	COG0436	Aminotransferase
GT347_23830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GT347_23835	COG1763	Mo-molybdopterin cofactor biosynthetic process
GT347_23850	COG0314	molybdopterin synthase activity
GT347_23860	COG0784	Response regulator, receiver
GT347_23860	COG4191	Histidine kinase
GT347_23870	COG0567	Dehydrogenase, E1 component
GT347_23875	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT347_23890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT347_23895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GT347_23910	COG1199	ATP-dependent helicase activity
GT347_23920	COG0564	pseudouridine synthase activity
GT347_23940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GT347_23955	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GT347_23960	COG0124	histidyl-tRNA synthetase
GT347_23975	COG1160	GTP binding
GT347_23980	COG1923	regulation of RNA biosynthetic process
GT347_23985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GT347_23990	COG0330	HflC and HflK could
GT347_23995	COG0330	HflC and HflK could
GT347_24005	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GT347_24010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GT347_24030	COG1846	Transcriptional regulator
GT347_24035	COG1538	Outer membrane efflux protein
GT347_24040	COG1566	PFAM secretion protein HlyD family protein
GT347_24075	COG4968	Prepilin-type N-terminal cleavage methylation domain
GT347_24080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT347_24105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT347_24120	COG1454	alcohol dehydrogenase
GT347_24125	COG2130	NADP-dependent
GT347_24130	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_24140	COG0628	permease
GT347_24160	COG1722	exodeoxyribonuclease VII activity
GT347_24165	COG0142	geranyltranstransferase activity
GT347_24170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GT347_24175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GT347_24190	COG0243	molybdopterin cofactor binding
GT347_24255	COG1012	belongs to the aldehyde dehydrogenase family
GT347_24265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GT347_24270	COG3706	GGDEF domain
GT347_24275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GT347_24280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT347_24285	COG0583	DNA-binding transcription factor activity
GT347_24290	COG1741	Belongs to the pirin family
GT347_24300	COG1741	Belongs to the pirin family
GT347_24310	COG0025	NhaP-type Na H and K H
GT347_24315	COG0477	Major facilitator Superfamily
GT347_24345	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_24360	COG0443	Heat shock 70 kDa protein
GT347_24375	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GT347_24380	COG0542	response to heat
GT347_24390	COG2925	Exonuclease
GT347_24415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GT347_24420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GT347_24425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GT347_24430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GT347_24435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GT347_24445	COG0776	regulation of translation
GT347_24480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT347_24510	COG2814	Major facilitator Superfamily
GT347_24520	COG0583	DNA-binding transcription factor activity
GT347_24535	COG3387	PFAM Glycoside hydrolase 15-related
GT347_24560	COG1802	Transcriptional regulator
GT347_24565	COG2084	Dehydrogenase
GT347_24575	COG2186	Transcriptional regulator
GT347_24580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_24585	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_24590	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_24640	COG2721	sulfolactate sulfo-lyase activity
GT347_24650	COG0473	3-isopropylmalate dehydrogenase activity
GT347_24655	COG0583	DNA-binding transcription factor activity
GT347_24665	COG0583	DNA-binding transcription factor activity
GT347_24670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_24700	COG1451	nucleotide metabolic process
GT347_24730	COG0747	negative chemotaxis
GT347_24740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_24755	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_24765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_24775	COG2885	chlorophyll binding
GT347_24800	COG2197	response regulator
GT347_24815	COG0515	serine threonine protein kinase
GT347_24820	COG0840	transmembrane signaling receptor activity
GT347_24845	COG0492	ferredoxin-NADP+ reductase activity
GT347_24855	COG0028	Belongs to the TPP enzyme family
GT347_24860	COG1414	Transcriptional regulator
GT347_24870	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_24895	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_24940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GT347_24940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GT347_24955	COG0438	transferase activity, transferring glycosyl groups
GT347_24960	COG2144	transferase activity, transferring acyl groups
GT347_24985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_25020	COG0583	DNA-binding transcription factor activity
GT347_25040	COG0625	glutathione transferase activity
GT347_25065	COG1360	Flagellar Motor Protein
GT347_25080	COG0631	protein serine/threonine phosphatase activity
GT347_25105	COG3501	Rhs element vgr protein
GT347_25220	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GT347_25225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GT347_25235	COG1595	DNA-templated transcription, initiation
GT347_25240	COG4944	Protein of unknown function (DUF1109)
GT347_25255	COG3093	addiction module antidote protein HigA
GT347_25270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_25275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT347_25285	COG0038	chloride channel
GT347_25295	COG0583	DNA-binding transcription factor activity
GT347_25355	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_25360	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_25365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GT347_25375	COG3128	pkhd-type hydroxylase
GT347_25400	COG0583	DNA-binding transcription factor activity
GT347_25405	COG1024	Enoyl-CoA hydratase
GT347_25415	COG1960	acyl-CoA dehydrogenase activity
GT347_25435	COG0386	Belongs to the glutathione peroxidase family
GT347_25445	COG2011	ABC-type metal ion transport system permease component
GT347_25455	COG1045	serine acetyltransferase
GT347_25510	COG3706	GGDEF domain
GT347_25535	COG0235	Class ii aldolase
GT347_25540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_25545	COG0697	spore germination
GT347_25565	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_25580	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_25655	COG3550	peptidyl-serine autophosphorylation
GT347_25665	COG4191	Histidine kinase
GT347_25665	COG0784	Response regulator, receiver
GT347_25695	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GT347_25705	COG1741	Belongs to the pirin family
GT347_25710	COG0583	DNA-binding transcription factor activity
GT347_25730	COG1840	ABC-type Fe3 transport system, periplasmic component
GT347_25735	COG3842	ATPase activity
GT347_25755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_25765	COG2828	Protein conserved in bacteria
GT347_25770	COG1733	regulation of RNA biosynthetic process
GT347_25775	COG0702	epimerase
GT347_25785	COG1595	DNA-templated transcription, initiation
GT347_25835	COG1012	belongs to the aldehyde dehydrogenase family
GT347_25855	COG0243	molybdopterin cofactor binding
GT347_25860	COG3279	Response regulator of the LytR AlgR family
GT347_25865	COG3275	phosphorelay sensor kinase activity
GT347_25880	COG1968	undecaprenyl-diphosphatase activity
GT347_25895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GT347_25915	COG2171	N-acyltransferase activity
GT347_25930	COG1289	transmembrane transporter activity
GT347_25945	COG1045	serine acetyltransferase
GT347_25960	COG0521	Mo-molybdopterin cofactor biosynthetic process
GT347_25965	COG3028	Belongs to the UPF0307 family
GT347_25970	COG0312	modulator of DNA gyrase
GT347_25985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GT347_25990	COG2081	HI0933 family
GT347_26015	COG1609	Transcriptional regulator
GT347_26030	COG1175	transmembrane transport
GT347_26035	COG0395	ABC-type sugar transport system, permease component
GT347_26040	COG1063	alcohol dehydrogenase
GT347_26045	COG3842	ATPase activity
GT347_26050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT347_26055	COG3684	Belongs to the aldolase LacD family
GT347_26060	COG0730	response to heat
GT347_26070	COG2188	Transcriptional regulator
GT347_26085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GT347_26090	COG0243	molybdopterin cofactor binding
GT347_26105	COG1116	anion transmembrane transporter activity
GT347_26110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_26115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_26125	COG3707	response regulator
GT347_26135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GT347_26145	COG0683	leucine binding
GT347_26155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GT347_26160	COG1185	polyribonucleotide nucleotidyltransferase activity
GT347_26165	COG0604	alcohol dehydrogenase
GT347_26165	COG3321	synthase
GT347_26170	COG0149	triose-phosphate isomerase activity
GT347_26185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_26190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_26195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_26200	COG0649	NAD binding
GT347_26205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GT347_26210	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GT347_26215	COG1034	ATP synthesis coupled electron transport
GT347_26220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GT347_26225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_26235	COG0713	ATP synthesis coupled electron transport
GT347_26250	COG1007	ATP synthesis coupled electron transport
GT347_26275	COG3237	CsbD-like
GT347_26285	COG0626	cystathionine gamma-synthase activity
GT347_26295	COG4181	ATPase activity
GT347_26300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT347_26305	COG2951	lytic endotransglycosylase activity
GT347_26320	COG0714	Associated with various cellular activities
GT347_26330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GT347_26330	COG3264	Mechanosensitive ion channel
GT347_26370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GT347_26370	COG3608	succinylglutamate desuccinylase aspartoacylase
GT347_26380	COG0840	transmembrane signaling receptor activity
GT347_26385	COG0604	alcohol dehydrogenase
GT347_26385	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_26385	COG3321	synthase
GT347_26405	COG4774	siderophore transport
GT347_26425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_26435	COG2917	probably involved in intracellular septation
GT347_26440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_26445	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GT347_26455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GT347_26475	COG2814	Major facilitator Superfamily
GT347_26485	COG1522	sequence-specific DNA binding
GT347_26490	COG0626	cystathionine gamma-synthase activity
GT347_26495	COG2072	flavoprotein involved in K transport
GT347_26530	COG0765	amino acid transport
GT347_26535	COG0765	amino acid transport
GT347_26555	COG1304	FMN binding
GT347_26565	COG0589	response to stress
GT347_26570	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_26575	COG0564	pseudouridine synthase activity
GT347_26585	COG0596	Alpha beta hydrolase
GT347_26610	COG1619	proteins homologs of microcin C7 resistance protein MccF
GT347_26615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT347_26635	COG3265	gluconokinase activity
GT347_26640	COG2271	Major facilitator Superfamily
GT347_26650	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_26700	COG0114	fumarate hydratase activity
GT347_26710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GT347_26715	COG2188	Transcriptional regulator
GT347_26775	COG0583	DNA-binding transcription factor activity
GT347_26790	COG0145	ligase activity
GT347_26795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_26820	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GT347_26840	COG0431	NADPH-dependent FMN reductase
GT347_26845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_26850	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GT347_26855	COG2080	2 iron, 2 sulfur cluster binding
GT347_26865	COG0454	-acetyltransferase
GT347_26880	COG0412	Dienelactone hydrolase
GT347_26900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GT347_26910	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_26920	COG2079	MmgE PrpD family protein
GT347_26935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_26965	COG0670	Belongs to the BI1 family
GT347_26975	COG0583	DNA-binding transcription factor activity
GT347_26980	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_26985	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_26995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_27015	COG0747	negative chemotaxis
GT347_27035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GT347_27055	COG0604	alcohol dehydrogenase
GT347_27055	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_27055	COG3321	synthase
GT347_27070	COG1802	Transcriptional regulator
GT347_27090	COG2814	Major facilitator Superfamily
GT347_27120	COG0084	hydrolase, TatD family'
GT347_27135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GT347_27140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GT347_27145	COG1192	Involved in chromosome partitioning
GT347_27210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT347_27215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair