locus-tag	class	description
AYJ57_00010	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AYJ57_00025	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AYJ57_00045	ENOG4108ZP8	Acetolactate synthase small subunit
AYJ57_00055	ENOG4105C7K	acetolactate synthase
AYJ57_00075	ENOG4105CH5	extracellular solute-binding protein, family 7
AYJ57_00085	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_00090	ENOG4105C3R	Methionine synthase
AYJ57_00100	ENOG4105DVW	rieske (2Fe-2S)
AYJ57_00105	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AYJ57_00110	ENOG4105C7K	acetolactate synthase
AYJ57_00115	ENOG4105EW9	transcriptional regulator AsnC family
AYJ57_00125	ENOG4105VDB	UPF0125 protein
AYJ57_00130	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
AYJ57_00145	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
AYJ57_00150	ENOG4108R3D	Electron transport complex
AYJ57_00160	ENOG4105KXW	Ferredoxin
AYJ57_00165	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
AYJ57_00175	ENOG4105U82	Ferredoxin
AYJ57_00185	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AYJ57_00215	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
AYJ57_00220	ENOG4108UR2	Nitrogen fixation protein NifX
AYJ57_00225	ENOG4108VQE	nitrogen fixation protein
AYJ57_00230	ENOG4105X87	nitrogen fixation
AYJ57_00235	ENOG4105WCA	Ferredoxin
AYJ57_00240	ENOG4105PS4	nifq family
AYJ57_00250	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
AYJ57_00255	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AYJ57_00260	ENOG4105C3J	Cysteine desulfurase
AYJ57_00265	ENOG4107S73	homocitrate synthase
AYJ57_00275	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
AYJ57_00280	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AYJ57_00285	ENOG4105E0C	molybdate abc transporter
AYJ57_00290	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_00300	ENOG4108UQY	Iron-storage protein
AYJ57_00305	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ57_00310	ENOG4108JUA	Transcriptional regulator
AYJ57_00315	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
AYJ57_00320	ENOG4107IVC	4Fe-4S ferredoxin, iron-sulfur binding
AYJ57_00325	ENOG4108QWQ	LRV FeS4 cluster domain protein
AYJ57_00330	ENOG4105XV5	nifz family
AYJ57_00360	ENOG4105ENX	hydrolase
AYJ57_00365	ENOG4105EQ2	LysR family Transcriptional regulator
AYJ57_00375	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AYJ57_00385	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AYJ57_00390	ENOG4106FI7	cytochrome c-type biogenesis protein
AYJ57_00395	ENOG4105DDR	sarcosine oxidase (Beta subunit)
AYJ57_00415	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AYJ57_00430	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AYJ57_00435	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AYJ57_00445	ENOG4105DEN	Luciferase family
AYJ57_00470	ENOG4105C94	Transporter
AYJ57_00480	ENOG4105YCT	UPF0386 protein
AYJ57_00485	ENOG4105C9B	Cysteine desulfurase
AYJ57_00490	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AYJ57_00500	ENOG41087AY	ADP-Ribose pyrophosphatase
AYJ57_00515	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AYJ57_00530	ENOG4105CNG	UPF0061 protein
AYJ57_00545	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AYJ57_00555	ENOG4107QP8	phosphohexose isomerase
AYJ57_00590	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ57_00595	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AYJ57_00605	ENOG4108YYH	Nadph-dependent fmn reductase
AYJ57_00610	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ57_00615	ENOG4105CKW	Inner membrane protein yedI
AYJ57_00625	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AYJ57_00655	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AYJ57_00670	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AYJ57_00675	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AYJ57_00680	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AYJ57_00685	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AYJ57_00690	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AYJ57_00700	ENOG4105FKQ	transcriptional regulator
AYJ57_00705	ENOG4105EPJ	extracellular solute-binding protein family 1
AYJ57_00710	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
AYJ57_00715	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
AYJ57_00720	ENOG4105CG3	alpha amylase, catalytic region
AYJ57_00725	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_00730	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AYJ57_00740	ENOG4108UKI	Enoyl-CoA hydratase
AYJ57_00750	ENOG4105DG4	malate L-lactate dehydrogenase
AYJ57_00775	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AYJ57_00800	ENOG4105C2C	drug resistance transporter, Bcr CflA
AYJ57_00815	ENOG4108IPT	Naphthoate synthase
AYJ57_00820	ENOG4105C1G	acyl-Coa dehydrogenase
AYJ57_00825	ENOG4107T8Q	Glycosyl transferase (Group 1
AYJ57_00830	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_00840	ENOG4105CH5	extracellular solute-binding protein, family 7
AYJ57_00845	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AYJ57_00850	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AYJ57_00860	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AYJ57_00875	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AYJ57_00880	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AYJ57_00885	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AYJ57_00890	ENOG4105KNE	Phosphatidate cytidylyltransferase
AYJ57_00895	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AYJ57_00900	ENOG4105DZP	Membrane-associated zinc metalloprotease
AYJ57_00915	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AYJ57_00920	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ57_00925	ENOG4105GYT	Protein of unknown function (DUF1009)
AYJ57_00930	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ57_00940	ENOG4105D7A	ATP-binding protein
AYJ57_00955	ENOG4105E43	Extracellular solute-binding protein, family 5
AYJ57_00970	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AYJ57_00980	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
AYJ57_00985	ENOG4108KPW	sugar kinase
AYJ57_00990	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AYJ57_01005	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AYJ57_01015	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AYJ57_01020	ENOG4105CE9	30S ribosomal protein S2
AYJ57_01040	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ57_01045	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AYJ57_01050	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_01055	ENOG4105E2Z	phosphate ABC transporter (Permease
AYJ57_01060	ENOG4105C8U	phosphate abc transporter
AYJ57_01070	ENOG4105BZU	Histidine kinase
AYJ57_01075	ENOG4105C28	cystathionine
AYJ57_01085	ENOG4108Z0R	Transferase
AYJ57_01090	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AYJ57_01095	ENOG4105DSJ	YicC domain protein
AYJ57_01105	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AYJ57_01110	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AYJ57_01135	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AYJ57_01140	ENOG4105ECQ	AraC Family Transcriptional Regulator
AYJ57_01145	ENOG4105D8V	Glucose sorbosone dehydrogenase
AYJ57_01150	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AYJ57_01155	ENOG4105C0Z	ABC transporter
AYJ57_01160	ENOG4108IV0	ABC, transporter
AYJ57_01175	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_01200	ENOG4107RTZ	reductase
AYJ57_01220	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AYJ57_01225	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AYJ57_01235	ENOG4105ECR	NmrA family
AYJ57_01240	ENOG4105KVH	Transcriptional regulator
AYJ57_01245	ENOG4105CHM	Aminotransferase
AYJ57_01255	ENOG4105CRQ	synthase (Component I)
AYJ57_01270	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AYJ57_01280	ENOG4105C3R	Methionine synthase
AYJ57_01295	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AYJ57_01310	ENOG4105DDQ	anthranilate synthase
AYJ57_01315	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AYJ57_01320	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AYJ57_01325	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AYJ57_01335	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AYJ57_01340	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AYJ57_01345	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AYJ57_01350	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AYJ57_01360	ENOG4105CGU	Enoyl-CoA hydratase
AYJ57_01370	ENOG4105KWW	Biogenesis protein
AYJ57_01375	ENOG4105DA4	cytochrome c-type biogenesis protein
AYJ57_01385	ENOG4105K46	50S ribosomal protein l27
AYJ57_01390	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AYJ57_01425	ENOG4108UM1	dedA family
AYJ57_01435	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ57_01450	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AYJ57_01455	ENOG41080XQ	Signal transduction protein with cbs domains
AYJ57_01465	ENOG4105C26	Dehydrogenase
AYJ57_01490	ENOG4105CAH	Chromate
AYJ57_01500	ENOG4105C9Q	fumarate hydratase class II
AYJ57_01520	ENOG4105C83	adenylosuccinate lyase
AYJ57_01550	ENOG4107QM5	aconitate hydratase
AYJ57_01565	ENOG4105DHQ	Histidine kinase
AYJ57_01570	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AYJ57_01575	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
AYJ57_01585	ENOG4105CMG	Carbohydrate kinase
AYJ57_01590	ENOG4105DEI	Mannitol dehydrogenase
AYJ57_01595	ENOG4105CHR	reductase
AYJ57_01600	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_01610	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
AYJ57_01625	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AYJ57_01635	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AYJ57_01640	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AYJ57_01645	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AYJ57_01650	ENOG4105D29	Helix-turn-helix type 11 domain protein
AYJ57_01665	ENOG4108ISG	Major Facilitator
AYJ57_01675	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AYJ57_01685	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AYJ57_01690	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AYJ57_01695	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AYJ57_01705	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AYJ57_01710	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AYJ57_01715	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AYJ57_01735	ENOG4108Z86	Glutamine amidotransferase
AYJ57_01745	ENOG4107QP3	malate synthase g
AYJ57_01750	ENOG4108JJ7	ABC transporter
AYJ57_01760	ENOG4108URH	decarboxylase
AYJ57_01775	ENOG4105WYW	fructose-bisphosphate aldolase
AYJ57_01790	ENOG4107QIV	Cytochrome c biogenesis protein
AYJ57_01795	ENOG4105C03	ribonuclease
AYJ57_01805	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AYJ57_01820	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AYJ57_01825	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AYJ57_01830	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AYJ57_01835	ENOG4105C1A	potassium transporter peripheral membrane
AYJ57_01840	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ57_01845	ENOG4105ES5	Histidine kinase
AYJ57_01855	ENOG4105CUX	Signal transduction histidine kinase
AYJ57_01860	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AYJ57_01865	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AYJ57_01870	ENOG4108ZAI	phosphatidylglycerophosphatase a
AYJ57_01875	ENOG4107TH8	cina domain protein
AYJ57_01880	ENOG4108Z1B	Cyclase dehydrase
AYJ57_01885	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AYJ57_01895	ENOG4105KA7	cytochrome C
AYJ57_01900	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AYJ57_01910	ENOG4105CUC	YeeE YedE family protein
AYJ57_01915	ENOG41080HT	Transcriptional regulator, arsr family
AYJ57_01925	ENOG4107QIV	Cytochrome c biogenesis protein
AYJ57_01955	ENOG4105CGH	5'-nucleotidase
AYJ57_01975	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AYJ57_01980	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
AYJ57_01990	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AYJ57_01995	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AYJ57_02005	ENOG4105CB5	ATP-dependent DNA helicase recG
AYJ57_02010	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AYJ57_02015	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AYJ57_02025	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AYJ57_02035	ENOG4105BZU	Histidine kinase
AYJ57_02045	ENOG4105CQZ	Histidine kinase
AYJ57_02050	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AYJ57_02055	ENOG4105CPQ	Dehydrogenase
AYJ57_02060	ENOG4105CVG	Homoserine O-transsuccinylase
AYJ57_02070	ENOG4105CSR	polyphosphate kinase 2
AYJ57_02080	ENOG4107T8Q	Glycosyl transferase (Group 1
AYJ57_02095	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AYJ57_02110	ENOG4105D49	3-dehydroquinate synthase
AYJ57_02115	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AYJ57_02125	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AYJ57_02130	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AYJ57_02135	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AYJ57_02155	ENOG4105E4C	Lytic transglycosylase catalytic
AYJ57_02160	ENOG4108UUM	single-stranded DNA-binding protein
AYJ57_02170	ENOG4108JU6	CBS domain protein
AYJ57_02190	ENOG410839H	phosphoribosylformylglycinamidine synthase
AYJ57_02195	ENOG4107QPR	SAICAR synthetase
AYJ57_02205	ENOG4105E0F	Histidine kinase
AYJ57_02210	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AYJ57_02220	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ57_02235	ENOG4105CYW	agmatinase
AYJ57_02265	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AYJ57_02275	ENOG4105ENH	Sulfatase
AYJ57_02290	ENOG4105CH6	catalase
AYJ57_02320	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AYJ57_02325	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AYJ57_02330	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AYJ57_02340	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AYJ57_02350	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ57_02350	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ57_02360	ENOG410814C	multidrug resistance protein
AYJ57_02365	ENOG4105CI3	gtp-binding protein typa
AYJ57_02390	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AYJ57_02435	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AYJ57_02440	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AYJ57_02450	ENOG4105JQN	Transcriptional regulator
AYJ57_02460	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AYJ57_02475	ENOG4105CTD	carboxy-peptidase
AYJ57_02480	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
AYJ57_02490	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AYJ57_02520	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AYJ57_02525	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AYJ57_02530	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AYJ57_02555	ENOG4105VG1	fes assembly suf system protein
AYJ57_02565	ENOG4105D9U	N-acetyltransferase
AYJ57_02570	ENOG4108Z4V	iron-sulfur cluster assembly
AYJ57_02575	ENOG4105CP7	Triose-phosphate isomerase
AYJ57_02585	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_02590	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
AYJ57_02595	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_02600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ57_02605	ENOG4105CQZ	Histidine kinase
AYJ57_02620	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AYJ57_02625	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AYJ57_02630	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ57_02635	ENOG4105C8S	subunit m
AYJ57_02640	ENOG4105D65	subunit l
AYJ57_02645	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ57_02650	ENOG4105DF2	NADH dehydrogenase subunit j
AYJ57_02655	ENOG4108048	decarboxylase
AYJ57_02665	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AYJ57_02675	ENOG4107R0R	NADH dehydrogenase subunit g
AYJ57_02695	ENOG4107QIZ	NADH dehydrogenase
AYJ57_02705	ENOG41080PD	NADH ubiquinone oxidoreductase 41 kD complex I subunit
AYJ57_02710	ENOG4105GKE	subunit e
AYJ57_02720	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ57_02725	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYJ57_02730	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ57_02735	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYJ57_02740	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AYJ57_02745	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AYJ57_02750	ENOG4108RXX	maleylacetoacetate isomerase
AYJ57_02760	ENOG4107QX3	carboxylase
AYJ57_02775	ENOG4105C1G	acyl-Coa dehydrogenase
AYJ57_02790	ENOG4105MSY	salicylate hydroxylase
AYJ57_02795	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYJ57_02800	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AYJ57_02805	ENOG4105C1J	atp-dependent rna helicase
AYJ57_02810	ENOG4108Z9K	Osmotically inducible protein
AYJ57_02820	ENOG4108XM1	transcriptional regulator AsnC family
AYJ57_02830	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AYJ57_02835	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AYJ57_02845	ENOG4105DP0	ferredoxin-NADP reductase
AYJ57_02850	ENOG4105CWC	Acetylornithine deacetylase
AYJ57_02885	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AYJ57_02895	ENOG4107XAN	XdhC and CoxI family
AYJ57_02915	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AYJ57_02920	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AYJ57_02930	ENOG4105C9B	Cysteine desulfurase
AYJ57_02945	ENOG4105JRK	feS assembly protein SufD
AYJ57_02950	ENOG4105C3K	feS assembly ATPase SufC
AYJ57_02960	ENOG4105K8R	UPF0145 protein
AYJ57_02980	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AYJ57_02985	ENOG4105DHZ	alpha beta
AYJ57_03000	ENOG4107QN2	dihydrolipoyl dehydrogenase
AYJ57_03025	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AYJ57_03035	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ57_03040	ENOG4105DR5	peptidase
AYJ57_03075	ENOG4105DXI	Major Facilitator superfamily
AYJ57_03085	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AYJ57_03090	ENOG4105C8N	cysteinyl-tRNA synthetase
AYJ57_03105	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AYJ57_03110	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AYJ57_03120	ENOG4105CYW	agmatinase
AYJ57_03125	ENOG4105CH2	amidohydrolase
AYJ57_03130	ENOG4105CH2	amidohydrolase
AYJ57_03135	ENOG4105DXN	mazG family
AYJ57_03145	ENOG4105FD8	phosphonate metabolism protein PhnM
AYJ57_03150	ENOG4108TXN	phosphonate metabolism protein
AYJ57_03160	ENOG4105HRV	phosphonate c-p lyase system protein phnl
AYJ57_03165	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
AYJ57_03190	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
AYJ57_03195	ENOG4107RJJ	Transcriptional regulator
AYJ57_03200	ENOG4105FD8	phosphonate metabolism protein PhnM
AYJ57_03205	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AYJ57_03230	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
AYJ57_03235	ENOG4105D5T	phosphonate abc transporter
AYJ57_03245	ENOG4108IGT	Dipeptidase
AYJ57_03250	ENOG4105DWF	phosphomethylpyrimidine kinase
AYJ57_03255	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AYJ57_03265	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AYJ57_03270	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AYJ57_03285	ENOG4105C0Z	ABC transporter
AYJ57_03290	ENOG4108IV0	ABC, transporter
AYJ57_03295	ENOG4108VHT	MarR family transcriptional regulator
AYJ57_03300	ENOG4105BZS	acriflavin resistance protein
AYJ57_03305	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AYJ57_03315	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AYJ57_03320	ENOG4105DJ9	glucan biosynthesis protein
AYJ57_03335	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_03340	ENOG4105C3U	ABC transporter
AYJ57_03345	ENOG4108JQ7	(ABC) transporter
AYJ57_03350	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_03360	ENOG4107QSI	ABC, transporter
AYJ57_03365	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AYJ57_03385	ENOG4105CHU	acetyl-coa acetyltransferase
AYJ57_03390	ENOG4107QNJ	CoA-transferase subunit B
AYJ57_03400	ENOG4107HP6	Transcriptional regulator
AYJ57_03415	ENOG4105EPW	hflc protein
AYJ57_03420	ENOG4107QJR	hflk protein
AYJ57_03430	ENOG4105E66	phosphoriboisomerase A
AYJ57_03435	ENOG4105EJQ	L-serine dehydratase
AYJ57_03445	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AYJ57_03455	ENOG4105C45	hydrogenase expression formation protein (HypE)
AYJ57_03460	ENOG4105CQS	hydrogenase expression formation protein HypD
AYJ57_03465	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
AYJ57_03470	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ57_03475	ENOG4107RSS	Hydrogenase accessory protein HypB
AYJ57_03480	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AYJ57_03485	ENOG4108ZBK	Inherit from NOG: hydrogenase expression formation protein HupK
AYJ57_03490	ENOG410631X	Hydrogenase expression formation protein
AYJ57_03495	ENOG4108UT5	Hydrogenase expression
AYJ57_03500	ENOG4105YYZ	Hydrogenase expression formation protein
AYJ57_03505	ENOG4105X9Y	Hydrogenase assembly chaperone hypC hupF
AYJ57_03510	ENOG4108USZ	hydrogenase
AYJ57_03515	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
AYJ57_03525	ENOG4105DPX	Hydrogenase, large subunit
AYJ57_03530	ENOG4105E3S	small subunit
AYJ57_03535	ENOG4105C8H	hydrogenase maturation protein Hypf
AYJ57_03540	ENOG4105DPX	Hydrogenase, large subunit
AYJ57_03565	ENOG4108JQ9	ABC transporter
AYJ57_03570	ENOG41083U2	ABC transporter, permease
AYJ57_03580	ENOG4105DZC	cytosine deaminase
AYJ57_03595	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AYJ57_03605	ENOG4105D6E	homoserine dehydrogenase
AYJ57_03635	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AYJ57_03645	ENOG4108YYC	ycei family
AYJ57_03650	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AYJ57_03660	ENOG4105C5R	Aminotransferase
AYJ57_03670	ENOG4105BZ1	(ABC) transporter
AYJ57_03675	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AYJ57_03690	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AYJ57_03710	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AYJ57_03725	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AYJ57_03750	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ57_03755	ENOG4105CFF	transcriptional regulator
AYJ57_03765	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_03775	ENOG4105C0Z	ABC transporter
AYJ57_03780	ENOG4108IV0	ABC, transporter
AYJ57_03785	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AYJ57_03800	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AYJ57_03805	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AYJ57_03835	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AYJ57_03840	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AYJ57_03845	ENOG4105PGM	cation diffusion facilitator family transporter
AYJ57_03855	ENOG41084CK	capsule polysaccharide
AYJ57_03865	ENOG4105E12	capsule polysaccharide
AYJ57_03870	ENOG4105FAV	ABC, transporter
AYJ57_03875	ENOG4105FDK	ABC transporter
AYJ57_03880	ENOG4105MYN	Zinc uptake regulation protein
AYJ57_03890	ENOG4108HUF	Transporter
AYJ57_03895	ENOG4105DQ5	transport system permease protein
AYJ57_03900	ENOG4108IHU	transport system permease protein
AYJ57_03905	ENOG4105E0A	ABC, transporter
AYJ57_03915	ENOG4105E7W	lamb ycsf family protein
AYJ57_03925	ENOG4105P4J	Allophanate hydrolase, subunit 1
AYJ57_03940	ENOG4105C03	ribonuclease
AYJ57_03955	ENOG4105ES4	Nitrilase
AYJ57_03995	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AYJ57_04010	ENOG4105P0I	Adenylate cyclase
AYJ57_04015	ENOG4107QJE	Chromosome Partitioning Protein
AYJ57_04035	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AYJ57_04040	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ57_04060	ENOG4105CFU	surface antigen
AYJ57_04075	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AYJ57_04080	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AYJ57_04085	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
AYJ57_04095	ENOG4105CQM	Urea amidohydrolase subunit alpha
AYJ57_04105	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AYJ57_04120	ENOG4105KI2	Urea amidohydrolase subunit beta
AYJ57_04125	ENOG4108YZ9	Urea amidohydrolase subunit gamma
AYJ57_04130	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AYJ57_04140	ENOG4108RTU	Aldolase
AYJ57_04145	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
AYJ57_04165	ENOG4105NPQ	Pfam:DUF403
AYJ57_04175	ENOG4105EMU	Dehydrogenase
AYJ57_04190	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AYJ57_04195	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AYJ57_04230	ENOG4105G9V	cytochrome C
AYJ57_04235	ENOG4105E43	Extracellular solute-binding protein, family 5
AYJ57_04240	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AYJ57_04245	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AYJ57_04250	ENOG4108JQ5	ABC transporter
AYJ57_04255	ENOG4105D4P	Coproporphyrinogen iii oxidase
AYJ57_04260	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AYJ57_04265	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AYJ57_04280	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AYJ57_04295	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AYJ57_04300	ENOG410810E	transcriptional regulator, lysR family
AYJ57_04305	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AYJ57_04335	ENOG4108YXU	transcriptional regulator AsnC family
AYJ57_04340	ENOG4105DCF	alanine dehydrogenase
AYJ57_04350	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AYJ57_04355	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
AYJ57_04375	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AYJ57_04385	ENOG4105CJN	penicillin-binding protein
AYJ57_04390	ENOG4105CNI	cell division protein FtsW
AYJ57_04395	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_04400	ENOG4105DJV	ribulose-phosphate 3-epimerase
AYJ57_04405	ENOG4105CHH	sulfate transporter
AYJ57_04415	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AYJ57_04420	ENOG410829K	Lysine exporter protein (Lyse ygga)
AYJ57_04430	ENOG4107R73	Mate efflux family protein
AYJ57_04460	ENOG4108K3A	Glutathione S-transferase
AYJ57_04475	ENOG4105EE1	crotonyl-CoA reductase
AYJ57_04480	ENOG4105RFZ	Methylmalonyl-coA mutase
AYJ57_04485	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AYJ57_04490	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AYJ57_04510	ENOG4105E33	succinate dehydrogenase
AYJ57_04520	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AYJ57_04525	ENOG4105PDA	succinate dehydrogenase, hydrophobic membrane anchor protein
AYJ57_04530	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AYJ57_04535	ENOG4105DJG	MaoC domain protein dehydratase
AYJ57_04550	ENOG4105CI0	Citrate lyase
AYJ57_04560	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
AYJ57_04565	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
AYJ57_04570	ENOG4108IJ8	ABC transporter
AYJ57_04575	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
AYJ57_04580	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AYJ57_04585	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AYJ57_04595	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AYJ57_04600	ENOG4105C7S	Dehydrogenase
AYJ57_04615	ENOG4107QN2	dihydrolipoyl dehydrogenase
AYJ57_04640	ENOG4105CAK	Cell division ATP-binding protein ftsE
AYJ57_04650	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AYJ57_04655	ENOG4108IY8	ABC, transporter
AYJ57_04665	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AYJ57_04680	ENOG4105FYV	Amp nucleosidase
AYJ57_04690	ENOG4105E4C	Lytic transglycosylase catalytic
AYJ57_04700	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AYJ57_04705	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AYJ57_04710	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AYJ57_04715	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AYJ57_04720	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AYJ57_04725	ENOG4105CTB	Polyprenyl synthetase
AYJ57_04730	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AYJ57_04740	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AYJ57_04745	ENOG41090HR	transcriptional regulator
AYJ57_04750	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AYJ57_04765	ENOG4105F38	ABC transporter, permease
AYJ57_04775	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_04780	ENOG4105CWC	Acetylornithine deacetylase
AYJ57_04790	ENOG4107QJN	gtp cyclohydrolase ii
AYJ57_04795	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ57_04805	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AYJ57_04810	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AYJ57_04830	ENOG4105W49	UPF0434 protein
AYJ57_04840	ENOG4105K63	Thioredoxin
AYJ57_04850	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AYJ57_04855	ENOG4105CGK	Exodeoxyribonuclease III
AYJ57_04870	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AYJ57_04875	ENOG4108JU5	Magnesium and cobalt efflux protein
AYJ57_04885	ENOG4105C9A	Phoh family
AYJ57_04895	ENOG41090EK	ompa motb domain protein
AYJ57_04900	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AYJ57_04910	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AYJ57_04915	ENOG41090R7	Ferric uptake
AYJ57_04920	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AYJ57_04925	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AYJ57_04930	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AYJ57_04940	ENOG4108UAU	isochorismatase
AYJ57_04945	ENOG4105J12	Multidrug resistance protein mdtN
AYJ57_04965	ENOG4105EW9	transcriptional regulator AsnC family
AYJ57_04985	ENOG4105ECY	inositol monophosphatase
AYJ57_05000	ENOG4105CBG	Sulfatase
AYJ57_05005	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AYJ57_05015	ENOG4105CHM	Aminotransferase
AYJ57_05045	ENOG4108UYE	Lactoylglutathione lyase
AYJ57_05060	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AYJ57_05090	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ57_05115	ENOG4105VDW	Csbd family
AYJ57_05135	ENOG4107RZC	phospholipase d
AYJ57_05140	ENOG4105DSF	transport protein
AYJ57_05165	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AYJ57_05185	ENOG4105DZR	Type I site-specific deoxyribonuclease
AYJ57_05195	ENOG4105CVR	type I restriction-modification system
AYJ57_05235	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AYJ57_05240	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AYJ57_05245	ENOG4108JJ8	(ABC) transporter
AYJ57_05250	ENOG4108JJ9	ABC, transporter
AYJ57_05265	ENOG4107SCA	Formamidase (EC 3.5.1.49)
AYJ57_05270	ENOG4105BZS	acriflavin resistance protein
AYJ57_05275	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AYJ57_05290	ENOG4108JEH	abc transporter atp-binding protein
AYJ57_05295	ENOG4105DRP	amino acid AbC transporter
AYJ57_05300	ENOG4105E5Q	amino acid AbC transporter
AYJ57_05305	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AYJ57_05310	ENOG4105CQB	FAD linked oxidase domain protein
AYJ57_05315	ENOG4105CGP	Urocanate hydratase
AYJ57_05325	ENOG4105C84	Histidine ammonia-lyase
AYJ57_05330	ENOG4105CI2	imidazolone-5-propionate hydrolase
AYJ57_05340	ENOG4105DSF	transport protein
AYJ57_05350	ENOG4107U9T	Pfam:Ribonuclease_BN
AYJ57_05360	ENOG4105CBD	Diacylglycerol kinase
AYJ57_05385	ENOG4105E0X	reductase
AYJ57_05395	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AYJ57_05405	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AYJ57_05425	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AYJ57_05430	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AYJ57_05440	ENOG4105C26	Dehydrogenase
AYJ57_05445	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AYJ57_05460	ENOG4105CGF	Aromatic amino acid aminotransferase
AYJ57_05465	ENOG4105KHC	sulfurtransferase
AYJ57_05470	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AYJ57_05480	ENOG4105S0E	allantoin catabolism protein
AYJ57_05485	ENOG4108Z2U	ureidoglycolate hydrolase
AYJ57_05515	ENOG4105CVE	Lytic murein transglycosylase
AYJ57_05535	ENOG4105E98	transcriptional regulator DeoR family
AYJ57_05540	ENOG4105MP9	class II Aldolase
AYJ57_05545	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AYJ57_05550	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
AYJ57_05555	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AYJ57_05560	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
AYJ57_05575	ENOG4107STW	synthase
AYJ57_05580	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AYJ57_05590	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AYJ57_05610	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AYJ57_05620	ENOG4108RW8	Universal stress protein F
AYJ57_05640	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AYJ57_05645	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AYJ57_05650	ENOG4105CEC	DNA methylase N-4 N-6
AYJ57_05660	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AYJ57_05665	ENOG4105DP9	ABC transporter
AYJ57_05675	ENOG4107T0D	ABC, transporter
AYJ57_05680	ENOG4105EIX	cytochrome c1
AYJ57_05685	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AYJ57_05690	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AYJ57_05700	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AYJ57_05705	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AYJ57_05720	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AYJ57_05730	ENOG4105DFI	Membrane
AYJ57_05745	ENOG4105DGW	oligopeptidase A
AYJ57_05750	ENOG4105E5Q	amino acid AbC transporter
AYJ57_05760	ENOG4105D06	uba thif-type nad fad binding protein
AYJ57_05765	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AYJ57_05770	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AYJ57_05780	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ57_05785	ENOG4105C0P	Mg chelatase subunit ChlI
AYJ57_05800	ENOG41082D8	UPF0102 protein
AYJ57_05805	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AYJ57_05815	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AYJ57_05825	ENOG4105C1J	atp-dependent rna helicase
AYJ57_05835	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AYJ57_05845	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AYJ57_05855	ENOG4105C31	Tryptophanyl-tRNA synthetase
AYJ57_05870	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AYJ57_05875	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AYJ57_05895	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
AYJ57_05905	ENOG4106BM2	Cupin domain
AYJ57_05910	ENOG4105CUC	YeeE YedE family protein
AYJ57_05915	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AYJ57_05920	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AYJ57_05925	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AYJ57_05930	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AYJ57_05940	ENOG4105DZ1	carboxypeptidase
AYJ57_05945	ENOG4105K5G	30S ribosomal protein S21
AYJ57_05965	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AYJ57_05970	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AYJ57_05985	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AYJ57_06000	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AYJ57_06005	ENOG41080HT	Transcriptional regulator, arsr family
AYJ57_06010	ENOG4105CEY	Amp-dependent synthetase and ligase
AYJ57_06015	ENOG4105BZ1	(ABC) transporter
AYJ57_06030	ENOG4108IXY	short-chain dehydrogenase reductase
AYJ57_06035	ENOG4108NIX	Factor ChrR
AYJ57_06040	ENOG4105K6V	RNA polymerase
AYJ57_06055	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AYJ57_06065	ENOG4108RAV	Conserved protein
AYJ57_06070	ENOG4108R99	pseudouridine synthase
AYJ57_06075	ENOG4108Z6B	deaminase
AYJ57_06080	ENOG4105FE9	pseudouridine synthase
AYJ57_06100	ENOG4105CDW	Resistance protein
AYJ57_06130	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AYJ57_06150	ENOG4105BZU	Histidine kinase
AYJ57_06165	ENOG4105VG0	50S ribosomal protein l34
AYJ57_06170	ENOG4105KK3	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AYJ57_06175	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AYJ57_06180	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AYJ57_06185	ENOG4105BZU	Histidine kinase
AYJ57_06190	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AYJ57_06200	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AYJ57_06205	ENOG4105CAS	nag kinase
AYJ57_06215	ENOG4105M4E	phosphohistidine phosphatase, SixA
AYJ57_06220	ENOG4105CDA	abc transporter atp-binding protein
AYJ57_06225	ENOG4105DRP	amino acid AbC transporter
AYJ57_06230	ENOG4105EZ7	amino acid ABC transporter
AYJ57_06235	ENOG4107QXX	ABC transporter
AYJ57_06245	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AYJ57_06250	ENOG4105EI2	Pseudouridine synthase
AYJ57_06260	ENOG4105D1H	recombination factor protein RarA
AYJ57_06265	ENOG4105C0H	protease
AYJ57_06270	ENOG4105EAC	phosphoserine phosphatase
AYJ57_06285	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AYJ57_06305	ENOG4105BZU	Histidine kinase
AYJ57_06315	ENOG4105WH1	Two component transcriptional regulator luxr family
AYJ57_06335	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AYJ57_06350	ENOG4108WBT	adenosyltransferase
AYJ57_06360	ENOG4105E1F	short-chain dehydrogenase reductase
AYJ57_06370	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ57_06375	ENOG4105TPV	
AYJ57_06410	ENOG4108RG0	uracil-dna glycosylase
AYJ57_06420	ENOG4105KXX	peptidase s58 dmpa
AYJ57_06440	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_06450	ENOG4105E09	nadh pyrophosphatase
AYJ57_06455	ENOG4105FD8	phosphonate metabolism protein PhnM
AYJ57_06460	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AYJ57_06465	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AYJ57_06470	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AYJ57_06485	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AYJ57_06490	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AYJ57_06495	ENOG4105EB3	Histidine kinase
AYJ57_06505	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AYJ57_06515	ENOG41080Z8	PHOSPHOCARRIER protein
AYJ57_06525	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AYJ57_06535	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AYJ57_06545	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AYJ57_06555	ENOG4107RUE	extracellular solute-binding protein family 1
AYJ57_06560	ENOG4105D38	putrescine abc transporter
AYJ57_06565	ENOG4105F38	ABC transporter, permease
AYJ57_06570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_06585	ENOG4105DVW	rieske (2Fe-2S)
AYJ57_06600	ENOG4105CA9	Pyruvate kinase
AYJ57_06610	ENOG41082BR	50S ribosomal protein L35
AYJ57_06615	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AYJ57_06620	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AYJ57_06640	ENOG4105C8T	Leucyl-tRNA synthetase
AYJ57_06645	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AYJ57_06650	ENOG4105TXM	Domain of unknown function (DUF3576)
AYJ57_06660	ENOG4107RDJ	Sulfotransferase
AYJ57_06665	ENOG4105DFA	alanine racemase domain protein
AYJ57_06670	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AYJ57_06680	ENOG4108ZZ3	UPF0260 protein
AYJ57_06685	ENOG4105C5W	Aldolase
AYJ57_06710	ENOG4105CHM	Aminotransferase
AYJ57_06720	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AYJ57_06730	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AYJ57_06735	ENOG4105CVE	Lytic murein transglycosylase
AYJ57_06745	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AYJ57_06750	ENOG4105CN1	protease
AYJ57_06760	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AYJ57_06765	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_06775	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_06805	ENOG41084XA	UPF0235 protein
AYJ57_06810	ENOG41069NU	Nitroreductase
AYJ57_06860	ENOG4105C9M	aspartyl-trna synthetase
AYJ57_06865	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AYJ57_06870	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AYJ57_06875	ENOG4108IV0	ABC, transporter
AYJ57_06880	ENOG4105C0Z	ABC transporter
AYJ57_06885	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AYJ57_06890	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_06905	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AYJ57_06910	ENOG4105E0C	molybdate abc transporter
AYJ57_06915	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_06950	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AYJ57_06955	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AYJ57_06960	ENOG4105D6Z	AFG1 family ATPase
AYJ57_06965	ENOG4105DCM	major facilitator superfamily
AYJ57_06970	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AYJ57_06980	ENOG4108UPT	UPF0178 protein
AYJ57_06985	ENOG4105C4W	S-formylglutathione hydrolase
AYJ57_07000	ENOG4105DA5	(ABC) transporter
AYJ57_07005	ENOG4105K59	histidine triad (HIT) protein
AYJ57_07025	ENOG4105CHR	reductase
AYJ57_07035	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AYJ57_07070	ENOG4105CQB	FAD linked oxidase domain protein
AYJ57_07075	ENOG4105EU8	FAD linked oxidase domain protein
AYJ57_07080	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AYJ57_07085	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
AYJ57_07095	ENOG4108ZNX	Heat shock protein
AYJ57_07105	ENOG4108JA1	polyketide synthase
AYJ57_07110	ENOG4105C5Q	Transcriptional regulator
AYJ57_07130	ENOG4105C26	Dehydrogenase
AYJ57_07140	ENOG4105RX8	Protein of unknown function (DUF1523)
AYJ57_07145	ENOG4105KAF	membrAne
AYJ57_07160	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AYJ57_07165	ENOG4105DB1	molybdopterin oxidoreductase
AYJ57_07180	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AYJ57_07190	ENOG4105EXC	Acyl-transferase
AYJ57_07210	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AYJ57_07220	ENOG4107T8Q	Glycosyl transferase (Group 1
AYJ57_07225	ENOG4106WTF	Glycosyl transferase, family 2
AYJ57_07235	ENOG4107YJ4	chain length determinant protein
AYJ57_07275	ENOG4105JNK	Glycosyl transferase (Group 1
AYJ57_07285	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AYJ57_07315	ENOG4105C2X	Arabinose 5-phosphate isomerase
AYJ57_07320	ENOG41067MG	lrgb family
AYJ57_07325	ENOG4105VAW	lrga family
AYJ57_07350	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AYJ57_07355	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AYJ57_07385	ENOG4105BZG	amino acid carrier protein
AYJ57_07395	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AYJ57_07405	ENOG4108R7K	Metal Dependent Phosphohydrolase
AYJ57_07425	ENOG4108ZX6	Electron transport protein SCO1 SenC
AYJ57_07430	ENOG4105TX3	Histidine kinase
AYJ57_07440	ENOG4108E87	P-loop hydrolase UPF0079
AYJ57_07445	ENOG4105EHM	Aminoglycoside phosphotransferase
AYJ57_07450	ENOG4108S0S	Nucleotidyl transferase
AYJ57_07455	ENOG4107RMM	double-strand break repair protein Addb
AYJ57_07465	ENOG4105K63	Thioredoxin
AYJ57_07475	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AYJ57_07480	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AYJ57_07500	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AYJ57_07505	ENOG4105CK2	sodium dicarboxylate symporter
AYJ57_07515	ENOG4105VW4	glutaredoxin 3
AYJ57_07520	ENOG4105MJ2	Competence protein
AYJ57_07530	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AYJ57_07555	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
AYJ57_07560	ENOG4107QS4	23S rRNA
AYJ57_07565	ENOG4105BZ1	(ABC) transporter
AYJ57_07570	ENOG4105BZ1	(ABC) transporter
AYJ57_07580	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AYJ57_07585	ENOG4105P8F	nudix hydrolase
AYJ57_07590	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AYJ57_07600	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ57_07610	ENOG4105C7B	Threonine dehydratase
AYJ57_07620	ENOG4105CDH	Citrulline--aspartate ligase
AYJ57_07635	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AYJ57_07640	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AYJ57_07650	ENOG4105C6K	Malic enzyme
AYJ57_07655	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AYJ57_07660	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AYJ57_07665	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AYJ57_07670	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AYJ57_07675	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AYJ57_07680	ENOG4105CSA	Coproporphyrinogen iii oxidase
AYJ57_07685	ENOG4105FA0	parb-like partition protein
AYJ57_07690	ENOG4107QJE	Chromosome Partitioning Protein
AYJ57_07695	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
AYJ57_07700	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AYJ57_07705	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AYJ57_07710	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AYJ57_07715	ENOG4108UHJ	MAF-like protein
AYJ57_07720	ENOG4105E2X	shikimate dehydrogenase
AYJ57_07725	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AYJ57_07730	ENOG4107RZZ	dna polymerase iii epsilon subunit
AYJ57_07735	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AYJ57_07740	ENOG4105FS0	cytoplasmic membrane protein
AYJ57_07760	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AYJ57_07770	ENOG4105DAY	polysaccharide export protein
AYJ57_07775	ENOG4105D3Q	Sugar transferase
AYJ57_07785	ENOG4105E3R	(LipO)protein
AYJ57_07790	ENOG4105ER2	Ompa motb domain protein
AYJ57_07820	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AYJ57_07825	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AYJ57_07830	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AYJ57_07845	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AYJ57_07850	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AYJ57_07855	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AYJ57_07860	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AYJ57_07865	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ57_07915	ENOG4107QSI	ABC, transporter
AYJ57_07920	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_07925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_07930	ENOG4108JQ6	ABC transporter
AYJ57_07935	ENOG4108WUH	Transcriptional regulator, TetR family
AYJ57_07940	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AYJ57_07950	ENOG4105DJP	Membrane
AYJ57_07955	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AYJ57_07970	ENOG4107QP7	CoA-transferase subunit A
AYJ57_07980	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AYJ57_07995	ENOG4105CHU	acetyl-coa acetyltransferase
AYJ57_08005	ENOG4105BZU	Histidine kinase
AYJ57_08010	ENOG4105D1Q	UPF0246 protein
AYJ57_08015	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AYJ57_08020	ENOG4108YZN	class I peptide chain release factor
AYJ57_08025	ENOG4105EX9	Membrane
AYJ57_08035	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
AYJ57_08080	ENOG4105CH7	arginosuccinase
AYJ57_08085	ENOG4107ZT5	Thiol disulfide interchange protein
AYJ57_08105	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AYJ57_08110	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AYJ57_08115	ENOG4108RWI	nicotinamidase
AYJ57_08120	ENOG4105C72	UPF0176 protein
AYJ57_08125	ENOG4105CN7	Flagellar biosynthetic protein FliP
AYJ57_08130	ENOG4105DD5	Flagellar motor switch protein
AYJ57_08140	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AYJ57_08160	ENOG4105K63	Thioredoxin
AYJ57_08165	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AYJ57_08180	ENOG4108I0Y	(ABC) transporter
AYJ57_08195	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AYJ57_08200	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AYJ57_08205	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AYJ57_08210	ENOG4105KPV	Transcriptional regulator
AYJ57_08220	ENOG4105EXU	Membrane
AYJ57_08225	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AYJ57_08250	ENOG4107E2E	PKHD-type hydroxylase
AYJ57_08260	ENOG4105C4K	Nad synthetase
AYJ57_08275	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AYJ57_08295	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_08305	ENOG4105F38	ABC transporter, permease
AYJ57_08315	ENOG410633P	Hydantoin racemase
AYJ57_08320	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AYJ57_08330	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
AYJ57_08335	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AYJ57_08340	ENOG4105D7T	ABC transporter
AYJ57_08365	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AYJ57_08380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_08385	ENOG4105F38	ABC transporter, permease
AYJ57_08390	ENOG4105D38	putrescine abc transporter
AYJ57_08395	ENOG4105CJP	fad dependent oxidoreductase
AYJ57_08400	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AYJ57_08410	ENOG4108YZA	Nitrogen regulatory protein pii
AYJ57_08415	ENOG4108JQC	penicillin-binding protein 1A
AYJ57_08420	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AYJ57_08450	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AYJ57_08465	ENOG4107QSV	RmuC domain protein
AYJ57_08470	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AYJ57_08480	ENOG4105M0C	cytoplasmic protein
AYJ57_08490	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AYJ57_08495	ENOG4105K8Z	Phage shock protein
AYJ57_08500	ENOG41073TP	transcriptional regulator
AYJ57_08505	ENOG4108ZAF	Molybdopterin
AYJ57_08515	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AYJ57_08520	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
AYJ57_08535	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AYJ57_08540	ENOG4105DFI	Membrane
AYJ57_08545	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AYJ57_08550	ENOG4105C3F	Signal peptidase i
AYJ57_08555	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AYJ57_08560	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AYJ57_08570	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AYJ57_08590	ENOG4105W39	Membrane
AYJ57_08595	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AYJ57_08615	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AYJ57_08620	ENOG4105EN6	Membrane
AYJ57_08625	ENOG4105C87	Aminotransferase class I and II
AYJ57_08630	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AYJ57_08635	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AYJ57_08640	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AYJ57_08645	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AYJ57_08655	ENOG4105CHF	Glutathione S-transferase
AYJ57_08675	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_08680	ENOG4105D0A	hydroxylase
AYJ57_08690	ENOG4105EMU	Dehydrogenase
AYJ57_08695	ENOG4108VUG	Enoyl-CoA hydratase
AYJ57_08700	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ57_08710	ENOG4105CPN	adenine deaminase
AYJ57_08730	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AYJ57_08755	ENOG4105C7B	Threonine dehydratase
AYJ57_08780	ENOG41077A9	carbonic anhydrase
AYJ57_08790	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AYJ57_08795	ENOG4107SN7	NLP P60 protein
AYJ57_08800	ENOG4105CYW	agmatinase
AYJ57_08815	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AYJ57_08820	ENOG4108JQ1	Dehydrogenase
AYJ57_08825	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AYJ57_08830	ENOG4105CHH	sulfate transporter
AYJ57_08840	ENOG41082FS	50S ribosomal protein L31
AYJ57_08845	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AYJ57_08850	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AYJ57_08860	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AYJ57_08870	ENOG4105K5M	30s ribosomal protein S16
AYJ57_08900	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYJ57_08925	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AYJ57_08930	ENOG4105VD1	ATP synthase subunit C
AYJ57_08935	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AYJ57_08940	ENOG4105N5Q	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AYJ57_08945	ENOG4105D1F	ATP-binding protein
AYJ57_08970	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AYJ57_08975	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AYJ57_08980	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_08985	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AYJ57_08995	ENOG4108NH8	Cation transport protein
AYJ57_09005	ENOG4105UYK	outer membrane protein a
AYJ57_09020	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AYJ57_09035	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AYJ57_09040	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AYJ57_09045	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AYJ57_09050	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AYJ57_09075	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AYJ57_09090	ENOG4105CXT	aspartate transcarbamylase
AYJ57_09095	ENOG4106H78	methyltransferase
AYJ57_09110	ENOG4105KZX	Pterin carbinolamine dehydratase
AYJ57_09140	ENOG410903C	(LipO)protein
AYJ57_09165	ENOG4105CBC	glutamate synthase
AYJ57_09170	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AYJ57_09175	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AYJ57_09210	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AYJ57_09250	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AYJ57_09255	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AYJ57_09260	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AYJ57_09265	ENOG4108VZM	50s ribosomal protein L10
AYJ57_09270	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AYJ57_09275	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AYJ57_09280	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AYJ57_09295	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AYJ57_09300	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AYJ57_09305	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AYJ57_09310	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AYJ57_09315	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AYJ57_09320	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AYJ57_09325	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AYJ57_09330	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AYJ57_09335	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AYJ57_09340	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AYJ57_09345	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AYJ57_09350	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AYJ57_09355	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AYJ57_09365	ENOG41083MP	50s ribosomal protein l29
AYJ57_09370	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AYJ57_09375	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AYJ57_09380	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AYJ57_09385	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AYJ57_09390	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AYJ57_09395	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AYJ57_09400	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AYJ57_09405	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AYJ57_09410	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AYJ57_09415	ENOG41084HQ	50S ribosomal protein L30
AYJ57_09420	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AYJ57_09425	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AYJ57_09430	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AYJ57_09440	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AYJ57_09445	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AYJ57_09450	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AYJ57_09460	ENOG4107QPD	alcohol dehydrogenase
AYJ57_09490	ENOG4105C2M	dna polymerase I
AYJ57_09500	ENOG4105CSM	endonuclease III
AYJ57_09505	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AYJ57_09510	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AYJ57_09515	ENOG4105D3Q	Sugar transferase
AYJ57_09520	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AYJ57_09530	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AYJ57_09535	ENOG4108IUZ	ABC transporter
AYJ57_09540	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
AYJ57_09545	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AYJ57_09575	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AYJ57_09585	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AYJ57_09600	ENOG4105CF1	Alkylated DNA repair protein
AYJ57_09605	ENOG4105CFG	Acts as a chaperone (By similarity)
AYJ57_09610	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AYJ57_09615	ENOG4105W5Q	DNA repair protein (RadC
AYJ57_09630	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AYJ57_09635	ENOG4107TF3	peptidylprolyl cis-trans isomerase
AYJ57_09640	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AYJ57_09645	ENOG4105M6F	mutator MutT protein
AYJ57_09650	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AYJ57_09665	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AYJ57_09690	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AYJ57_09695	ENOG4105EAH	synthase
AYJ57_09705	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AYJ57_09710	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
AYJ57_09715	ENOG4105CHR	reductase
AYJ57_09730	ENOG4105CXC	rtn protein
AYJ57_09735	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AYJ57_09740	ENOG4108R86	Transcriptional regulator
AYJ57_09745	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
AYJ57_09750	ENOG4105CD3	dihydroorotase
AYJ57_09765	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AYJ57_09770	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AYJ57_09790	ENOG4105DIQ	Transcriptional regulator
AYJ57_09805	ENOG4108KB2	LysR family Transcriptional regulator
AYJ57_09810	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AYJ57_09830	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AYJ57_09840	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AYJ57_09850	ENOG4105F7P	transcriptional regulator AsnC family
AYJ57_09855	ENOG4105C3M	thioredoxin reductase
AYJ57_09865	ENOG4107RIQ	Sulfate adenylate transferase
AYJ57_09875	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AYJ57_09885	ENOG4108ZNX	Heat shock protein
AYJ57_09895	ENOG4105II7	pyrroline-5-carboxylate reductase
AYJ57_09900	ENOG4108Z7R	Chaperone CsaA
AYJ57_09910	ENOG4107104	thymidine kinase
AYJ57_09935	ENOG4105E3A	(ABC) transporter
AYJ57_09940	ENOG4105VE1	Phosphatidylcholine synthase
AYJ57_09950	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AYJ57_09955	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AYJ57_09975	ENOG4105PSV	Polysaccharide Biosynthesis Protein
AYJ57_10010	ENOG4105D3Q	Sugar transferase
AYJ57_10020	ENOG4105E2K	Glycosyl transferase (Group 1
AYJ57_10035	ENOG4108KBP	metal-dependent protein hydrolase
AYJ57_10040	ENOG4105CSU	acyl-Coa dehydrogenase
AYJ57_10055	ENOG4105E4E	Thioester reductase domain-containing protein
AYJ57_10060	ENOG4105E9F	Enoyl-CoA hydratase
AYJ57_10070	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_10090	ENOG4105QPS	Monooxygenase
AYJ57_10105	ENOG4108UAU	isochorismatase
AYJ57_10110	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
AYJ57_10115	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_10120	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
AYJ57_10125	ENOG41073TP	transcriptional regulator
AYJ57_10140	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_10145	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AYJ57_10150	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AYJ57_10160	ENOG4105X1V	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AYJ57_10165	ENOG4105C1G	acyl-Coa dehydrogenase
AYJ57_10180	ENOG4105FBA	Phospholipase Carboxylesterase
AYJ57_10195	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AYJ57_10215	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
AYJ57_10235	ENOG4105C5H	ABC transporter
AYJ57_10240	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AYJ57_10255	ENOG4105DK7	lysyl-tRNA synthetase
AYJ57_10265	ENOG4105QNJ	serralysin (EC 3.4.24.40)
AYJ57_10275	ENOG4107QMS	site-determining protein
AYJ57_10285	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AYJ57_10290	ENOG4105C25	Primosomal protein n'
AYJ57_10295	ENOG4105EW9	transcriptional regulator AsnC family
AYJ57_10310	ENOG4105K4P	CoA-binding domain protein
AYJ57_10315	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
AYJ57_10320	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AYJ57_10325	ENOG4105CGH	5'-nucleotidase
AYJ57_10330	ENOG4108JGH	Tetr family transcriptional regulator
AYJ57_10350	ENOG4105K89	arsenate reductase
AYJ57_10355	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AYJ57_10360	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AYJ57_10365	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AYJ57_10370	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AYJ57_10395	ENOG4105C4R	Atp-dependent dna helicase
AYJ57_10405	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AYJ57_10420	ENOG4107RCH	Diaminopropionate ammonia-lyase
AYJ57_10425	ENOG4105DDW	LysR family Transcriptional regulator
AYJ57_10430	ENOG4105C1G	acyl-Coa dehydrogenase
AYJ57_10435	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AYJ57_10475	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AYJ57_10480	ENOG4105CFH	Aspartokinase
AYJ57_10490	ENOG4105CHR	reductase
AYJ57_10505	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AYJ57_10515	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AYJ57_10525	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AYJ57_10530	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AYJ57_10535	ENOG4107XZX	Involved in the transcription termination process (By similarity)
AYJ57_10585	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ57_10600	ENOG4105DWP	Membrane
AYJ57_10605	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AYJ57_10610	ENOG4105CJP	fad dependent oxidoreductase
AYJ57_10615	ENOG4105CFQ	glutamine synthetase
AYJ57_10620	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AYJ57_10625	ENOG4105CFQ	glutamine synthetase
AYJ57_10630	ENOG4105DMR	ABC, transporter
AYJ57_10635	ENOG4105GBT	ABC transporter
AYJ57_10660	ENOG4105D6S	protein involved in catabolism of external DNA
AYJ57_10670	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AYJ57_10695	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AYJ57_10700	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AYJ57_10715	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AYJ57_10720	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AYJ57_10725	ENOG4107SQ0	N-acetyl-gamma-glutamyl-phosphate reductase
AYJ57_10730	ENOG4105C3G	gtp-binding protein
AYJ57_10735	ENOG4107QI1	Mate efflux family protein
AYJ57_10755	ENOG4105CSR	polyphosphate kinase 2
AYJ57_10765	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AYJ57_10770	ENOG4105ZXK	Dehydrogenase
AYJ57_10775	ENOG4105G63	Type III effector Hrp-dependent
AYJ57_10780	ENOG4105FB2	class II Aldolase
AYJ57_10785	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AYJ57_10790	ENOG4105C5I	Dehydrogenase
AYJ57_10800	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AYJ57_10810	ENOG4105CQB	FAD linked oxidase domain protein
AYJ57_10825	ENOG4105CHR	reductase
AYJ57_10835	ENOG4105FKQ	transcriptional regulator
AYJ57_10850	ENOG4105C01	Dihydroxy-acid dehydratase
AYJ57_10855	ENOG4105DTD	Dehydrogenase
AYJ57_10865	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AYJ57_10870	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AYJ57_10875	ENOG4105CTX	dehydratase
AYJ57_10880	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_10890	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_10895	ENOG4105DRR	Transcriptional regulator, GntR family
AYJ57_10930	ENOG4108M0I	Transcriptional regulator
AYJ57_10935	ENOG4105CQB	FAD linked oxidase domain protein
AYJ57_10940	ENOG410804X	Transcriptional regulator
AYJ57_10950	ENOG4108JU3	Alkyl hydroperoxide reductase
AYJ57_10955	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AYJ57_10965	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
AYJ57_10970	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_10975	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AYJ57_10985	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_10995	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
AYJ57_11015	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_11020	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_11045	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
AYJ57_11055	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_11095	ENOG4105CTD	carboxy-peptidase
AYJ57_11100	ENOG4108JQ7	(ABC) transporter
AYJ57_11105	ENOG4105C3U	ABC transporter
AYJ57_11110	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_11115	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_11150	ENOG4105D44	asparaginase
AYJ57_11175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AYJ57_11190	ENOG4107JPU	
AYJ57_11195	ENOG4107YD3	Thioesterase
AYJ57_11205	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AYJ57_11210	ENOG4105CSU	acyl-Coa dehydrogenase
AYJ57_11220	ENOG4105CHU	acetyl-coa acetyltransferase
AYJ57_11230	ENOG4105CEY	Amp-dependent synthetase and ligase
AYJ57_11235	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
AYJ57_11250	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
AYJ57_11255	ENOG4108K1J	Transporter DctQ
AYJ57_11260	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_11270	ENOG4105CTX	dehydratase
AYJ57_11275	ENOG4105CTX	dehydratase
AYJ57_11280	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AYJ57_11300	ENOG4107Z7P	Ferredoxin
AYJ57_11310	ENOG4105D48	metallophosphoesterase
AYJ57_11325	ENOG4105CDY	transcriptional regulatory protein
AYJ57_11350	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AYJ57_11360	ENOG4105W0E	50S ribosomal protein L33
AYJ57_11380	ENOG4105HFZ	Membrane
AYJ57_11390	ENOG4107NQ8	LysR family Transcriptional regulator
AYJ57_11400	ENOG4108WRK	Transcriptional regulator
AYJ57_11405	ENOG4107TK4	histidinol-phosphate phosphatase
AYJ57_11410	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AYJ57_11425	ENOG4107QUY	Guanine deaminase
AYJ57_11430	ENOG4105CJW	magnesium transporter
AYJ57_11435	ENOG4107XQK	5-formyltetrahydrofolate cyclo-ligase
AYJ57_11440	ENOG4105C12	Phosphoribosylglycinamide synthetase
AYJ57_11450	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AYJ57_11460	ENOG4107SC1	transglycosylase
AYJ57_11465	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AYJ57_11470	ENOG4105KT7	mgtC SapB transporter
AYJ57_11475	ENOG4107835	probably involved in intracellular septation (By similarity)
AYJ57_11480	ENOG4105CSH	Transporter
AYJ57_11490	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AYJ57_11510	ENOG4105F8V	Hydrolase, tatD family
AYJ57_11520	ENOG4107YZH	Cell division protein mraZ
AYJ57_11525	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AYJ57_11540	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AYJ57_11550	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AYJ57_11555	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AYJ57_11565	ENOG4105CBX	hi0933 family
AYJ57_11575	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AYJ57_11580	ENOG4105DFU	Cell wall formation (By similarity)
AYJ57_11595	ENOG4105D4A	Cell wall formation (By similarity)
AYJ57_11600	ENOG4105CPF	Cell wall formation (By similarity)
AYJ57_11605	ENOG4108UFP	Essential cell division protein (By similarity)
AYJ57_11610	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AYJ57_11615	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AYJ57_11620	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ57_11625	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ57_11635	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AYJ57_11650	ENOG4105D1F	ATP-binding protein
AYJ57_11655	ENOG4107QRG	dna polymerase iii
AYJ57_11660	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AYJ57_11665	ENOG4105DZ1	carboxypeptidase
AYJ57_11745	ENOG4105CE1	Ferrous iron transport protein b
AYJ57_11760	ENOG4105I8F	Histidine kinase
AYJ57_11795	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AYJ57_11800	ENOG4105TS0	gtp-binding protein
AYJ57_11815	ENOG4105D6J	arsenicaL-resistance protein
AYJ57_11820	ENOG4105CAU	Arsenical resistance protein, ArsH
AYJ57_11830	ENOG4105HEI	LysR family (Transcriptional regulator
AYJ57_11845	ENOG4105CHR	reductase
AYJ57_11855	ENOG4107P2S	Transcriptional regulator
AYJ57_11890	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AYJ57_11895	ENOG4105CCU	oxidase (Subunit III)
AYJ57_11900	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AYJ57_11905	ENOG4105E2S	oxidase) subunit II
AYJ57_11920	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AYJ57_11925	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AYJ57_11930	ENOG4105PDP	Short chain dehydrogenase
AYJ57_11940	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AYJ57_11975	ENOG4105CY3	ABC transporter, permease
AYJ57_11980	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AYJ57_11990	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AYJ57_11995	ENOG4105EKE	dihydroorotase
AYJ57_12025	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AYJ57_12035	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AYJ57_12055	ENOG4105CHM	Aminotransferase
AYJ57_12060	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AYJ57_12070	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_12085	ENOG4108JQ6	ABC transporter
AYJ57_12090	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AYJ57_12095	ENOG4107QMS	site-determining protein
AYJ57_12105	ENOG4105CFG	Acts as a chaperone (By similarity)
AYJ57_12110	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AYJ57_12120	ENOG4105CH2	amidohydrolase
AYJ57_12130	ENOG4105D8X	mechanosensitive ion channel
AYJ57_12140	ENOG4105BZU	Histidine kinase
AYJ57_12150	ENOG4105C0B	DNA polymerase III (alpha subunit)
AYJ57_12155	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
AYJ57_12165	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AYJ57_12170	ENOG4109066	lysm domain bon superfamily protein
AYJ57_12195	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AYJ57_12205	ENOG4108UHU	Aldolase
AYJ57_12210	ENOG4105C01	Dihydroxy-acid dehydratase
AYJ57_12225	ENOG4105KJM	monovalent cation h antiporter subunit g
AYJ57_12230	ENOG4105W4C	monovalent cation H antiporter subunit F
AYJ57_12235	ENOG4105SC1	monovalent cation H antiporter subunit E
AYJ57_12245	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AYJ57_12250	ENOG4105D65	subunit l
AYJ57_12255	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_12305	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AYJ57_12325	ENOG4105CHR	reductase
AYJ57_12330	ENOG4105F1N	DNA alkylation repair
AYJ57_12340	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AYJ57_12355	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AYJ57_12400	ENOG4105E18	UPF0276 protein
AYJ57_12415	ENOG4105D0M	Protease HtpX homolog
AYJ57_12420	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ57_12425	ENOG4105P0T	Usg family
AYJ57_12435	ENOG4105D52	delta-aminolevulinic acid dehydratase
AYJ57_12460	ENOG4107T5V	SNARE associated Golgi
AYJ57_12465	ENOG4105CY2	Citrate transporter
AYJ57_12470	ENOG4105C3Q	Glycosyl transferase, family 2
AYJ57_12475	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
AYJ57_12480	ENOG4105SYT	Methylenetetrahydrofolate reductase
AYJ57_12485	ENOG4105DZ2	Transcriptional regulator
AYJ57_12495	ENOG4105KUZ	arsenate reductase
AYJ57_12500	ENOG4105C22	threonyL-tRNA synthetase
AYJ57_12550	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AYJ57_12565	ENOG4105CXN	decarboxylase
AYJ57_12570	ENOG4107T0X	DNA ligase
AYJ57_12600	ENOG4105VEJ	Heat shock protein
AYJ57_12605	ENOG4108Z4U	Ferredoxin
AYJ57_12610	ENOG4108VJ1	Transcriptional regulator (CarD family
AYJ57_12615	ENOG4105CEP	NADH dehydrogenase
AYJ57_12620	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AYJ57_12630	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AYJ57_12640	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AYJ57_12645	ENOG4105CQB	FAD linked oxidase domain protein
AYJ57_12655	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AYJ57_12660	ENOG4105K56	Transcriptional regulator
AYJ57_12670	ENOG4107T6F	Xaa-Pro aminopeptidase
AYJ57_12710	ENOG4105E0X	reductase
AYJ57_12730	ENOG4105DKK	Benzoate
AYJ57_12760	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_12780	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AYJ57_12785	ENOG4105CD8	aminopeptidase N
AYJ57_12800	ENOG4105BZS	acriflavin resistance protein
AYJ57_12825	ENOG4105C8Y	Acetylornithine aminotransferase
AYJ57_12840	ENOG4105F1S	paraquat-inducible protein a
AYJ57_12845	ENOG4105DY2	Paraquat-inducible protein b
AYJ57_12865	ENOG4105C5H	ABC transporter
AYJ57_12875	ENOG4108IRC	dna polymerase iii
AYJ57_12890	ENOG4107QN1	sodium solute
AYJ57_12900	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AYJ57_12905	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AYJ57_12920	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_12930	ENOG41074H6	response regulator
AYJ57_12950	ENOG4108Z86	Glutamine amidotransferase
AYJ57_12965	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AYJ57_12985	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AYJ57_12990	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
AYJ57_13010	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AYJ57_13015	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AYJ57_13020	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
AYJ57_13025	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AYJ57_13030	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AYJ57_13035	ENOG41060IM	Heme exporter protein
AYJ57_13045	ENOG4107QX9	Thiol disulfide interChange protein
AYJ57_13050	ENOG4107XYW	BioY family
AYJ57_13080	ENOG4105C5F	glutamine synthetase
AYJ57_13085	ENOG4108YZA	Nitrogen regulatory protein pii
AYJ57_13090	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AYJ57_13115	ENOG4107U14	binding-protein-dependent transport systems inner membrane Component
AYJ57_13135	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AYJ57_13140	ENOG4105CKK	Glycosyl transferase, family 2
AYJ57_13165	ENOG4105FAW	cDP-glucose 4,6-dehydratase
AYJ57_13170	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
AYJ57_13190	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AYJ57_13200	ENOG4105CKK	Glycosyl transferase, family 2
AYJ57_13225	ENOG4107QQG	Dehydrogenase
AYJ57_13240	ENOG4107T8Q	Glycosyl transferase (Group 1
AYJ57_13270	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AYJ57_13275	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AYJ57_13290	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_13300	ENOG4105RD8	TRAP dicarboxylate transporter
AYJ57_13310	ENOG4108IV0	ABC, transporter
AYJ57_13315	ENOG4105C0Z	ABC transporter
AYJ57_13320	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_13325	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_13350	ENOG4105DAE	Methylenetetrahydrofolate reductase
AYJ57_13365	ENOG4105C9X	ppx gppa phosphatase
AYJ57_13370	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AYJ57_13425	ENOG4108UQY	Iron-storage protein
AYJ57_13455	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AYJ57_13460	ENOG4105HHA	aminodeoxychorismate lyase
AYJ57_13465	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AYJ57_13470	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AYJ57_13475	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AYJ57_13480	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AYJ57_13495	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AYJ57_13505	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AYJ57_13510	ENOG4108WIW	Aspartyl protease
AYJ57_13515	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AYJ57_13520	ENOG4105C5H	ABC transporter
AYJ57_13525	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AYJ57_13545	ENOG4105CHM	Aminotransferase
AYJ57_13575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_13655	ENOG4105D7W	serine acetyltransferase
AYJ57_13660	ENOG4105F27	Major Facilitator
AYJ57_13665	ENOG4105C7S	Dehydrogenase
AYJ57_13670	ENOG4105CPP	Dehydrogenase, E1 component
AYJ57_13675	ENOG4108JYK	Dehydrogenase
AYJ57_13680	ENOG4106ABQ	septum formation initiator
AYJ57_13685	ENOG4105BZA	Phosphoglycerate kinase
AYJ57_13690	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AYJ57_13695	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AYJ57_13715	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
AYJ57_13735	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AYJ57_13745	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AYJ57_13750	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AYJ57_13755	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AYJ57_13760	ENOG4105C75	arginyL-tRNA synthetase
AYJ57_13770	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AYJ57_13775	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AYJ57_13780	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AYJ57_13795	ENOG4105DHP	deoxycytidine triphosphate deaminase
AYJ57_13805	ENOG4105WJX	transcriptional regulator MERR family
AYJ57_13810	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AYJ57_13815	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AYJ57_13820	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AYJ57_13825	ENOG41082GS	50S ribosomal protein L32
AYJ57_13915	ENOG4105D38	putrescine abc transporter
AYJ57_13920	ENOG4105F38	ABC transporter, permease
AYJ57_13930	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_13935	ENOG4108UDW	Transcriptional regulator, luxr family
AYJ57_13945	ENOG4108JQ6	ABC transporter
AYJ57_13950	ENOG4107SCA	Formamidase (EC 3.5.1.49)
AYJ57_13955	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_13965	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_13985	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AYJ57_13990	ENOG41081R2	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AYJ57_14005	ENOG4107WCG	it plays a direct role in the translocation of protons across the membrane (By similarity)
AYJ57_14015	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AYJ57_14020	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AYJ57_14025	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AYJ57_14040	ENOG4107QWP	ABC-2 type transporter
AYJ57_14045	ENOG4105CJ1	ABC, transporter
AYJ57_14065	ENOG4105HDK	L-asparaginase
AYJ57_14070	ENOG4108IJ0	Aspartate ammonia-lyase
AYJ57_14085	ENOG4105GAK	amidohydrolase 2
AYJ57_14100	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_14110	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_14115	ENOG4105EMY	transcriptional regulator
AYJ57_14130	ENOG4105DQ4	alcohol dehydrogenase
AYJ57_14140	ENOG4105CPC	Aldo Keto reductase
AYJ57_14145	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AYJ57_14155	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AYJ57_14195	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AYJ57_14200	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AYJ57_14225	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AYJ57_14230	ENOG4105CSU	acyl-Coa dehydrogenase
AYJ57_14235	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AYJ57_14240	ENOG4108UJU	UPF0301 protein
AYJ57_14260	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AYJ57_14270	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AYJ57_14285	ENOG4105DIK	(ABC) transporter
AYJ57_14290	ENOG4105CC5	ABC transporter
AYJ57_14295	ENOG4105CC5	ABC transporter
AYJ57_14300	ENOG4105CPQ	Dehydrogenase
AYJ57_14305	ENOG4105C2J	ABC transporter
AYJ57_14310	ENOG4105CNN	ABC, transporter
AYJ57_14315	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
AYJ57_14325	ENOG4105G6Z	alkaline phosphatase
AYJ57_14335	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AYJ57_14345	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AYJ57_14355	ENOG4108IHU	transport system permease protein
AYJ57_14360	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_14365	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AYJ57_14370	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AYJ57_14390	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AYJ57_14405	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AYJ57_14425	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AYJ57_14430	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AYJ57_14440	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AYJ57_14455	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AYJ57_14465	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
AYJ57_14490	ENOG4105UIB	(ABC) transporter
AYJ57_14495	ENOG4108JQ9	ABC transporter
AYJ57_14500	ENOG4105DIH	basic membrane
AYJ57_14510	ENOG41072GX	Peptidase M22 Glycoprotease
AYJ57_14515	ENOG41083MR	nifu domain-containing protein
AYJ57_14530	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AYJ57_14540	ENOG4105DMF	Dehydrogenase
AYJ57_14550	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AYJ57_14560	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AYJ57_14570	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AYJ57_14575	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AYJ57_14580	ENOG4105C02	permease
AYJ57_14590	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AYJ57_14600	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AYJ57_14610	ENOG4105C8P	)-transporter
AYJ57_14630	ENOG4105C79	DNA protecting protein DprA
AYJ57_14635	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AYJ57_14640	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AYJ57_14645	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AYJ57_14655	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AYJ57_14660	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AYJ57_14665	ENOG4108R6F	Surfeit locus 1 family protein
AYJ57_14670	ENOG4105D98	threonine synthase
AYJ57_14675	ENOG4105C1V	Peptidase, M16
AYJ57_14695	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AYJ57_14700	ENOG4105VNH	ABC transporter solute-binding protein
AYJ57_14705	ENOG4105CXZ	ABC transporter, permease
AYJ57_14710	ENOG4108VGW	abc transporter atp-binding protein
AYJ57_14715	ENOG4105CMG	Carbohydrate kinase
AYJ57_14725	ENOG4105E09	nadh pyrophosphatase
AYJ57_14730	ENOG4105CGH	5'-nucleotidase
AYJ57_14745	ENOG4107YBY	Hydrolase
AYJ57_14800	ENOG4105FFC	UPF0187 protein
AYJ57_14805	ENOG4105CUT	histidyl-tRNA synthetase
AYJ57_14810	ENOG4105P5X	ATP phosphoribosyltransferase regulatory subunit
AYJ57_14815	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AYJ57_14825	ENOG4105CYM	Glutathione S-transferase
AYJ57_14830	ENOG4107QRT	dEAD DEAH box helicase
AYJ57_14835	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AYJ57_14845	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AYJ57_14850	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AYJ57_14855	ENOG4105CKU	formyltetrahydrofolate synthetase
AYJ57_14865	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AYJ57_14870	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AYJ57_14875	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AYJ57_14885	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AYJ57_14900	ENOG4108ZZF	transport protein (ExbD)
AYJ57_14905	ENOG4105E02	MotA TolQ exbB proton channel
AYJ57_14915	ENOG4108IJ9	(ABC) transporter
AYJ57_14920	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
AYJ57_14945	ENOG4105BZU	Histidine kinase
AYJ57_14955	ENOG4108SHN	Glycosyl transferase, family 2
AYJ57_14960	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AYJ57_14985	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AYJ57_14990	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AYJ57_15010	ENOG41083UI	stage II sporulation protein
AYJ57_15015	ENOG4105CHU	acetyl-coa acetyltransferase
AYJ57_15020	ENOG4105D3G	Pseudouridine synthase
AYJ57_15045	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AYJ57_15055	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AYJ57_15060	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
AYJ57_15065	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
AYJ57_15075	ENOG4105CBC	glutamate synthase
AYJ57_15080	ENOG4107XWI	flavin reductase domain protein, FMN-binding
AYJ57_15095	ENOG4105F38	ABC transporter, permease
AYJ57_15115	ENOG4107RZC	phospholipase d
AYJ57_15140	ENOG4105EQR	Transposase IS116 IS110 IS902
AYJ57_15155	ENOG4107RSM	transcriptional regulator
AYJ57_15170	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_15195	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AYJ57_15245	ENOG4105C0D	helicase
AYJ57_15290	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AYJ57_15300	ENOG4105BZU	Histidine kinase
AYJ57_15315	ENOG4105EMN	RNA polymerase sigma factor
AYJ57_15325	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AYJ57_15330	ENOG410811B	TRANSCRIPTIONal
AYJ57_15335	ENOG4105EV9	Alpha Beta Hydrolase
AYJ57_15360	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AYJ57_15375	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
AYJ57_15380	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
AYJ57_15405	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_15410	ENOG4105CH5	extracellular solute-binding protein, family 7
AYJ57_15415	ENOG4105C5F	glutamine synthetase
AYJ57_15420	ENOG4105C26	Dehydrogenase
AYJ57_15430	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AYJ57_15455	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AYJ57_15460	ENOG4105DBV	ornithine carbamoyltransferase
AYJ57_15465	ENOG4105C8Y	Acetylornithine aminotransferase
AYJ57_15470	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AYJ57_15475	ENOG4105CM6	amino acid regulated cytosolic protein
AYJ57_15485	ENOG4106K28	UPF0283 membrane protein
AYJ57_15500	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AYJ57_15515	ENOG4105KJF	protein tyrosine phosphatase
AYJ57_15520	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AYJ57_15530	ENOG4105KDC	50s ribosomal protein l28
AYJ57_15535	ENOG4105DJT	lAO AO transport system ATPase
AYJ57_15540	ENOG4105CWC	Acetylornithine deacetylase
AYJ57_15545	ENOG4105CPN	adenine deaminase
AYJ57_15555	ENOG4105D38	putrescine abc transporter
AYJ57_15560	ENOG4105F38	ABC transporter, permease
AYJ57_15565	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_15575	ENOG4105DUM	transcriptional regulator, lysR family
AYJ57_15580	ENOG4105C26	Dehydrogenase
AYJ57_15585	ENOG4105H3G	oxidoreductase
AYJ57_15590	ENOG4105CQ7	ATP-dependent helicase
AYJ57_15620	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AYJ57_15660	ENOG4105II7	pyrroline-5-carboxylate reductase
AYJ57_15705	ENOG4108KQ5	Integrase catalytic subunit
AYJ57_15780	ENOG4105P8Q	Curli production assembly transport component CsgG
AYJ57_15855	ENOG4105MP9	class II Aldolase
AYJ57_15860	ENOG4108M9J	MaoC like domain protein
AYJ57_15865	ENOG410903D	sensor protein
AYJ57_15870	ENOG4105BZU	Histidine kinase
AYJ57_15875	ENOG41074H6	response regulator
AYJ57_15895	ENOG4105DRR	Transcriptional regulator, GntR family
AYJ57_15905	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_15910	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_15915	ENOG4105C3U	ABC transporter
AYJ57_15925	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AYJ57_15930	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AYJ57_15940	ENOG4106KNT	transcriptional regulator
AYJ57_15955	ENOG4108RW8	Universal stress protein F
AYJ57_15960	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AYJ57_15970	ENOG4105C2C	drug resistance transporter, Bcr CflA
AYJ57_15985	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_15990	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
AYJ57_16000	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_16005	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AYJ57_16020	ENOG4105C0W	non-ribosomal peptide synthetase
AYJ57_16025	ENOG4105WQI	isochorismatase
AYJ57_16030	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AYJ57_16035	ENOG410642W	LysR family Transcriptional regulator
AYJ57_16040	ENOG4107YV9	domain protein
AYJ57_16045	ENOG4105C7W	Xanthine dehydrogenase
AYJ57_16060	ENOG4107QUY	Guanine deaminase
AYJ57_16065	ENOG4105S0E	allantoin catabolism protein
AYJ57_16070	ENOG41069M3	Transcriptional regulator
AYJ57_16100	ENOG4108Z2U	ureidoglycolate hydrolase
AYJ57_16110	ENOG4105CC0	LysR family Transcriptional regulator
AYJ57_16140	ENOG4109015	Biopolymer transport protein exbD tolR
AYJ57_16175	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AYJ57_16195	ENOG4107RNG	ABC transporter
AYJ57_16205	ENOG4105DFW	ABC transporter
AYJ57_16215	ENOG4107EJG	GntR family transcriptional regulator
AYJ57_16220	ENOG41062B0	ABC transporter, permease
AYJ57_16225	ENOG4107R9N	ABC transporter
AYJ57_16230	ENOG4105C2J	ABC transporter
AYJ57_16235	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
AYJ57_16255	ENOG4105C9F	isomerase
AYJ57_16275	ENOG4105C2J	ABC transporter
AYJ57_16280	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
AYJ57_16285	ENOG4105CNN	ABC, transporter
AYJ57_16290	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
AYJ57_16300	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
AYJ57_16305	ENOG4105EW9	transcriptional regulator AsnC family
AYJ57_16320	ENOG4108JGH	Tetr family transcriptional regulator
AYJ57_16335	ENOG4105C1J	atp-dependent rna helicase
AYJ57_16340	ENOG4105CJ3	phosphate transporter
AYJ57_16350	ENOG4105C88	aminopeptidase
AYJ57_16360	ENOG4106NZI	LysR family Transcriptional regulator
AYJ57_16380	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AYJ57_16385	ENOG4105DHU	Bile acid
AYJ57_16390	ENOG4105H3G	oxidoreductase
AYJ57_16405	ENOG4105C2X	Arabinose 5-phosphate isomerase
AYJ57_16420	ENOG4105CJ2	(LipO)protein
AYJ57_16425	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AYJ57_16430	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AYJ57_16435	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AYJ57_16455	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AYJ57_16465	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AYJ57_16470	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AYJ57_16475	ENOG4107SFI	Major Facilitator superfamily
AYJ57_16480	ENOG4105D64	Mechanosensitive ion channel
AYJ57_16485	ENOG4105D3R	alkyl hydroperoxide reductase
AYJ57_16500	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AYJ57_16515	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AYJ57_16525	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AYJ57_16545	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AYJ57_16555	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AYJ57_16565	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AYJ57_16585	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ57_16590	ENOG4107SC1	transglycosylase
AYJ57_16595	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AYJ57_16610	ENOG4105DRR	Transcriptional regulator, GntR family
AYJ57_16620	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AYJ57_16645	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AYJ57_16660	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_16665	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_16675	ENOG4105CFF	transcriptional regulator
AYJ57_16685	ENOG4107QX3	carboxylase
AYJ57_16710	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AYJ57_16730	ENOG4108Z7F	N-acetyltransferase
AYJ57_16735	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AYJ57_16755	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AYJ57_16775	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AYJ57_16780	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AYJ57_16810	ENOG4105VUF	Transcriptional regulator
AYJ57_16815	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AYJ57_16825	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AYJ57_16830	ENOG4105C26	Dehydrogenase
AYJ57_16835	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AYJ57_16840	ENOG4105CHF	Glutathione S-transferase
AYJ57_16845	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
AYJ57_16850	ENOG4105CBN	LysR family transcriptional regulator
AYJ57_16855	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AYJ57_16875	ENOG4105C0Z	ABC transporter
AYJ57_16880	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_16900	ENOG4108IV0	ABC, transporter
AYJ57_16905	ENOG4107XID	2'-5' rna ligase
AYJ57_16910	ENOG4105DZS	Phenylacetate-CoA ligase
AYJ57_16915	ENOG4107SWE	Methyltransferase
AYJ57_16940	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AYJ57_16950	ENOG4105EQ2	LysR family Transcriptional regulator
AYJ57_16955	ENOG4105CHR	reductase
AYJ57_16965	ENOG41066VF	YeeE YedE family protein
AYJ57_16975	ENOG4105F27	Major Facilitator
AYJ57_16980	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AYJ57_16990	ENOG4105CAT	Cytidine monophosphate kinase
AYJ57_16995	ENOG4105CPC	Aldo Keto reductase
AYJ57_17020	ENOG41080ZE	Adenylate cyclase
AYJ57_17035	ENOG4105CEN	a g-specific adenine glycosylase
AYJ57_17050	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AYJ57_17055	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AYJ57_17060	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AYJ57_17065	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AYJ57_17105	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AYJ57_17110	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AYJ57_17120	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AYJ57_17130	ENOG4105CGZ	zinc metallopeptidase
AYJ57_17150	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_17155	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AYJ57_17160	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
AYJ57_17170	ENOG4108IV0	ABC, transporter
AYJ57_17175	ENOG4105C0Z	ABC transporter
AYJ57_17185	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_17215	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AYJ57_17220	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AYJ57_17230	ENOG4108VYJ	response regulator receiver protein
AYJ57_17235	ENOG4105BZU	Histidine kinase
AYJ57_17240	ENOG4108V3W	Chemotaxis protein, CheW
AYJ57_17245	ENOG4105CBS	Chea signal transduction histidine kinase
AYJ57_17250	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ57_17260	ENOG4105C7K	acetolactate synthase
AYJ57_17275	ENOG4107JHD	SlyX family
AYJ57_17285	ENOG4105C0B	DNA polymerase III (alpha subunit)
AYJ57_17310	ENOG4108JQ9	ABC transporter
AYJ57_17315	ENOG4105UIB	(ABC) transporter
AYJ57_17355	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AYJ57_17360	ENOG4105D94	Major Facilitator Superfamily
AYJ57_17380	ENOG4108BAS	reductase
AYJ57_17390	ENOG4105G63	Type III effector Hrp-dependent
AYJ57_17405	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_17410	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_17435	ENOG4105MYN	Zinc uptake regulation protein
AYJ57_17440	ENOG4105FDK	ABC transporter
AYJ57_17445	ENOG4105FAV	ABC, transporter
AYJ57_17450	ENOG4105C3M	thioredoxin reductase
AYJ57_17455	ENOG41062ES	Transcriptional regulator
AYJ57_17465	ENOG4105CKI	cobalamin synthesis protein
AYJ57_17490	ENOG4105H3G	oxidoreductase
AYJ57_17525	ENOG4107SQD	Transcriptional regulator, GntR family
AYJ57_17530	ENOG4105F9U	Dehydrogenase
AYJ57_17535	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_17545	ENOG4105CH5	extracellular solute-binding protein, family 7
AYJ57_17550	ENOG4105CPQ	Dehydrogenase
AYJ57_17555	ENOG4105CHR	reductase
AYJ57_17560	ENOG4105CXK	mandelate racemase muconate lactonizing
AYJ57_17570	ENOG4105ETS	cytosine purines uracil thiamine allantoin
AYJ57_17590	ENOG4105C2J	ABC transporter
AYJ57_17595	ENOG4105CNN	ABC, transporter
AYJ57_17600	ENOG4108HWW	ABC transporter
AYJ57_17610	ENOG4105EQ2	LysR family Transcriptional regulator
AYJ57_17615	ENOG4105F27	Major Facilitator
AYJ57_17625	ENOG410810E	transcriptional regulator, lysR family
AYJ57_17630	ENOG4107S4Y	M20 DapE family protein YgeY
AYJ57_17640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_17650	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_17665	ENOG4105C0Z	ABC transporter
AYJ57_17670	ENOG4108IV0	ABC, transporter
AYJ57_17675	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_17700	ENOG4105C5I	Dehydrogenase
AYJ57_17730	ENOG4105D3W	isochorismatase
AYJ57_17755	ENOG4105E7U	AraC family transcriptional regulator
AYJ57_17785	ENOG4105C32	Amino acid ABC transporter (Permease)
AYJ57_17795	ENOG4105C0Z	ABC transporter
AYJ57_17800	ENOG4108IV0	ABC, transporter
AYJ57_17805	ENOG4105D3W	isochorismatase
AYJ57_17830	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AYJ57_17895	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AYJ57_17900	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_17905	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_17915	ENOG4108JQ7	(ABC) transporter
AYJ57_17920	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_17925	ENOG4105DIA	mandelate racemase muconate lactonizing
AYJ57_17930	ENOG4105JXH	GntR family transcriptional regulator
AYJ57_17960	ENOG4105D38	putrescine abc transporter
AYJ57_18005	ENOG4107YNJ	LysR family Transcriptional regulator
AYJ57_18010	ENOG4105K6H	D-cysteine desulfhydrase
AYJ57_18015	ENOG4107RP9	extracellular solute-binding protein, family 3
AYJ57_18020	ENOG4105EAD	ABC transporter
AYJ57_18025	ENOG4105DRP	amino acid AbC transporter
AYJ57_18030	ENOG4105CDA	abc transporter atp-binding protein
AYJ57_18050	ENOG4105EQR	Transposase IS116 IS110 IS902
AYJ57_18085	ENOG4105EQR	Transposase IS116 IS110 IS902
AYJ57_18130	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AYJ57_18135	ENOG4108VP3	Lysine exporter protein (LysE YggA)
AYJ57_18140	ENOG4105F7P	transcriptional regulator AsnC family
AYJ57_18145	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AYJ57_18155	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AYJ57_18175	ENOG4107S8C	mandelate racemase muconate lactonizing
AYJ57_18180	ENOG4105F0I	Aminotransferase
AYJ57_18205	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AYJ57_18210	ENOG4105DG4	malate L-lactate dehydrogenase
AYJ57_18220	ENOG4105C5I	Dehydrogenase
AYJ57_18225	ENOG4108JQ6	ABC transporter
AYJ57_18230	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_18240	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_18245	ENOG4106NZI	LysR family Transcriptional regulator
AYJ57_18250	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AYJ57_18260	ENOG4105DJV	ribulose-phosphate 3-epimerase
AYJ57_18265	ENOG4106F1P	AAA ATPase, central domain protein
AYJ57_18270	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
AYJ57_18275	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AYJ57_18280	ENOG4105D2N	Aldolase
AYJ57_18285	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ57_18290	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AYJ57_18295	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AYJ57_18300	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AYJ57_18305	ENOG4105DUM	transcriptional regulator, lysR family
AYJ57_18350	ENOG4107SQD	Transcriptional regulator, GntR family
AYJ57_18360	ENOG4107F9Y	LysR family transcriptional regulator
AYJ57_18375	ENOG4105JSC	dimethylmenaquinone methyltransferase
AYJ57_18395	ENOG4105H3G	oxidoreductase
AYJ57_18435	ENOG4105WH1	Two component transcriptional regulator luxr family
AYJ57_18440	ENOG4105D3Q	Sugar transferase
AYJ57_18455	ENOG4105CND	Glycosyl transferase, family 2
AYJ57_18460	ENOG4105K64	Glycosyl transferase, family 2
AYJ57_18465	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AYJ57_18470	ENOG4107EJG	GntR family transcriptional regulator
AYJ57_18495	ENOG4105CHR	reductase
AYJ57_18500	ENOG4105CPQ	Dehydrogenase
AYJ57_18510	ENOG4105NTW	Transcriptional regulator
AYJ57_18520	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ57_18540	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_18550	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_18555	ENOG4105E9Z	Nad-dependent epimerase dehydratase
AYJ57_18565	ENOG4105CXK	mandelate racemase muconate lactonizing
AYJ57_18570	ENOG4105GAK	amidohydrolase 2
AYJ57_18580	ENOG4107XII	Glycosyl Hydrolase Family 88
AYJ57_18595	ENOG4108IJ9	(ABC) transporter
AYJ57_18600	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
AYJ57_18605	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
AYJ57_18625	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AYJ57_18630	ENOG4105CHR	reductase
AYJ57_18685	ENOG4107S76	domain protein
AYJ57_18710	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AYJ57_18720	ENOG4105Y2X	UPF0335 protein
AYJ57_18730	ENOG4105MP9	class II Aldolase
AYJ57_18735	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_18740	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_18745	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_18750	ENOG4108JQ6	ABC transporter
AYJ57_18755	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_18760	ENOG4105EUF	amidase EC 3.5.1.4
AYJ57_18765	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_18775	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_18815	ENOG4105C8Y	Acetylornithine aminotransferase
AYJ57_18820	ENOG4105C26	Dehydrogenase
AYJ57_18825	ENOG4108RYR	transcriptional regulator AsnC family
AYJ57_18830	ENOG4105ENR	peptidase, M24
AYJ57_18860	ENOG4108M8W	Monooxygenase
AYJ57_18870	ENOG4105CPD	ethanolamine ammonia-lyase
AYJ57_18885	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
AYJ57_18890	ENOG4108JQ6	ABC transporter
AYJ57_18900	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_18915	ENOG410804X	Transcriptional regulator
AYJ57_18960	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AYJ57_18975	ENOG4105C94	Transporter
AYJ57_18985	ENOG4105EYU	Glutamine amido-transferase
AYJ57_18990	ENOG4105M90	Glutamate synthase alpha subunit domain protein
AYJ57_18995	ENOG4105CBC	glutamate synthase
AYJ57_19010	ENOG4107Y80	Major Facilitator superfamily
AYJ57_19030	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AYJ57_19045	ENOG4105D9P	serine threonine protein kinase
AYJ57_19050	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
AYJ57_19070	ENOG4107TTD	cytosine deaminase
AYJ57_19090	ENOG4105D7T	ABC transporter
AYJ57_19110	ENOG4105DRR	Transcriptional regulator, GntR family
AYJ57_19130	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AYJ57_19135	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AYJ57_19140	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AYJ57_19145	ENOG4105C7W	Xanthine dehydrogenase
AYJ57_19150	ENOG41080ZE	Adenylate cyclase
AYJ57_19165	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_19170	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AYJ57_19205	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AYJ57_19210	ENOG4105D64	Mechanosensitive ion channel
AYJ57_19215	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AYJ57_19220	ENOG4105C26	Dehydrogenase
AYJ57_19225	ENOG4108M8W	Monooxygenase
AYJ57_19230	ENOG4108MXF	Alpha Beta Hydrolase
AYJ57_19240	ENOG4105ETT	transcriptional Regulator, LysR family
AYJ57_19245	ENOG4105D7W	serine acetyltransferase
AYJ57_19255	ENOG4105CH2	amidohydrolase
AYJ57_19260	ENOG4108KB2	LysR family Transcriptional regulator
AYJ57_19270	ENOG4105C26	Dehydrogenase
AYJ57_19290	ENOG4108WUH	Transcriptional regulator, TetR family
AYJ57_19300	ENOG4108Z7G	MaoC domain protein dehydratase
AYJ57_19315	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AYJ57_19325	ENOG4105C6K	Malic enzyme
AYJ57_19335	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AYJ57_19360	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AYJ57_19370	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AYJ57_19380	ENOG4105CJP	fad dependent oxidoreductase
AYJ57_19385	ENOG4105D01	(LipO)protein
AYJ57_19390	ENOG4108UMI	ABC transporter, permease
AYJ57_19395	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_19410	ENOG4105C26	Dehydrogenase
AYJ57_19415	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AYJ57_19430	ENOG4108IJ7	Glycine betaine
AYJ57_19450	ENOG4105DHJ	ABC, transporter
AYJ57_19455	ENOG4105CY3	ABC transporter, permease
AYJ57_19460	ENOG4105ETE	Transcriptional regulator (LacI family
AYJ57_19470	ENOG4105F38	ABC transporter, permease
AYJ57_19480	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_19485	ENOG4105DU0	nucleoside hydrolase
AYJ57_19495	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
AYJ57_19500	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AYJ57_19505	ENOG4105S64	Formate nitrite transporter
AYJ57_19515	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AYJ57_19545	ENOG4105F1G	UPF0441 protein
AYJ57_19550	ENOG4106032	Glutathionylspermidine synthase
AYJ57_19570	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_19575	ENOG4105EXW	epimerase dehydratase
AYJ57_19580	ENOG4107YCY	Transcriptional regulator
AYJ57_19585	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AYJ57_19595	ENOG4105HDK	L-asparaginase
AYJ57_19605	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AYJ57_19610	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AYJ57_19615	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AYJ57_19635	ENOG4107RNH	Outer membrane receptor FepA
AYJ57_19640	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AYJ57_19650	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AYJ57_19660	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
AYJ57_19665	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AYJ57_19670	ENOG4108IJ9	(ABC) transporter
AYJ57_19675	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_19680	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AYJ57_19685	ENOG4105E98	transcriptional regulator DeoR family
AYJ57_19700	ENOG4105DHQ	Histidine kinase
AYJ57_19735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_19745	ENOG4108RZE	Tetr family transcriptional regulator
AYJ57_19750	ENOG4107S9B	Shikimate dehydrogenase
AYJ57_19755	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_19765	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_19770	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AYJ57_19780	ENOG4105CEY	Amp-dependent synthetase and ligase
AYJ57_19790	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_19800	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_19805	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ57_19815	ENOG4105C1G	acyl-Coa dehydrogenase
AYJ57_19840	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_19845	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_19850	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
AYJ57_19860	ENOG4106NZI	LysR family Transcriptional regulator
AYJ57_19870	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ57_19875	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ57_19895	ENOG410846T	CoA-transferase family III
AYJ57_19900	ENOG4107TH8	cina domain protein
AYJ57_19920	ENOG4105EXG	Transcriptional regulator
AYJ57_19925	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AYJ57_19930	ENOG4105HEI	LysR family (Transcriptional regulator
AYJ57_19935	ENOG4105WH1	Two component transcriptional regulator luxr family
AYJ57_19940	ENOG4105BZU	Histidine kinase
AYJ57_19945	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AYJ57_19950	ENOG4105C2J	ABC transporter
AYJ57_19960	ENOG4105CNN	ABC, transporter
AYJ57_19970	ENOG4107RKG	DJ-1/PfpI family
AYJ57_20020	ENOG4107Z6A	sulfate abc transporter permease
AYJ57_20030	ENOG4105BZM	domain protein
AYJ57_20035	ENOG4105DG4	malate L-lactate dehydrogenase
AYJ57_20040	ENOG4105CH2	amidohydrolase
AYJ57_20050	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AYJ57_20065	ENOG4105CHR	reductase
AYJ57_20070	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_20080	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_20110	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_20120	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
AYJ57_20125	ENOG4105FDP	GntR family transcriptional regulator
AYJ57_20135	ENOG4105DDW	LysR family Transcriptional regulator
AYJ57_20165	ENOG4105CE4	GlcNAc 6-P deacetylase
AYJ57_20185	ENOG4105DH8	myo-inositol catabolism
AYJ57_20190	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
AYJ57_20195	ENOG4105D7K	pfkb domain protein
AYJ57_20200	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
AYJ57_20210	ENOG4105D9R	oxidoreductase
AYJ57_20215	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
AYJ57_20220	ENOG4105CIB	oxidoreductase Domain protein
AYJ57_20225	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AYJ57_20230	ENOG4105F0H	myo-inositol catabolism protein
AYJ57_20235	ENOG4105C2J	ABC transporter
AYJ57_20240	ENOG4105CNN	ABC, transporter
AYJ57_20245	ENOG4105CNN	ABC, transporter
AYJ57_20255	ENOG4105ETE	Transcriptional regulator (LacI family
AYJ57_20260	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
AYJ57_20315	ENOG41061MV	Arylsulfatase
AYJ57_20320	ENOG4107QIJ	Aconitate hydratase 2
AYJ57_20325	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AYJ57_20380	ENOG4105BZS	acriflavin resistance protein
AYJ57_20460	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
AYJ57_20465	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AYJ57_20470	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AYJ57_20495	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_20505	ENOG4105F0I	Aminotransferase
AYJ57_20525	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AYJ57_20535	ENOG41063TF	transcriptional regulator (AraC
AYJ57_20550	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AYJ57_20570	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AYJ57_20580	ENOG4108RWI	nicotinamidase
AYJ57_20590	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AYJ57_20595	ENOG4105C4K	Nad synthetase
AYJ57_20650	ENOG4105F8V	Hydrolase, tatD family
AYJ57_20655	ENOG4108JJ6	Type I secretion system ATPase
AYJ57_20865	ENOG41088T4	Helicase IV
AYJ57_20905	ENOG4108KQ5	Integrase catalytic subunit
AYJ57_21015	ENOG4105FUA	antagonist
AYJ57_21020	ENOG4107MMM	Anti-sigma-factor antagonist
AYJ57_21025	ENOG41074H6	response regulator
AYJ57_21040	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AYJ57_21055	ENOG4108KQ5	Integrase catalytic subunit
AYJ57_21060	ENOG4105F27	Major Facilitator
AYJ57_21070	ENOG4105C3M	thioredoxin reductase
AYJ57_21075	ENOG4105K63	Thioredoxin
AYJ57_21085	ENOG4105VW4	glutaredoxin 3
AYJ57_21095	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AYJ57_21100	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
AYJ57_21110	ENOG4105C87	Aminotransferase class I and II
AYJ57_21120	ENOG4105ENH	Sulfatase
AYJ57_21125	ENOG4105EQR	Transposase IS116 IS110 IS902
AYJ57_21140	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AYJ57_21150	ENOG4105WBN	Transcriptional regulator (LacI family
AYJ57_21210	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AYJ57_21215	ENOG4105DDV	Transcriptional regulator (LacI family
AYJ57_21220	ENOG4105CHR	reductase
AYJ57_21225	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_21235	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_21350	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AYJ57_21385	ENOG4108KQ5	Integrase catalytic subunit
AYJ57_21415	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AYJ57_21495	ENOG4108VVQ	metallophosphoesterase
AYJ57_21555	ENOG4105EFI	regulatoR
AYJ57_21585	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AYJ57_21590	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AYJ57_21615	ENOG4105ER2	Ompa motb domain protein
AYJ57_21620	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AYJ57_21700	ENOG4105EQR	Transposase IS116 IS110 IS902
AYJ57_21720	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AYJ57_21730	ENOG4106TNF	Periplasmic binding protein
AYJ57_21735	ENOG4105E5Q	amino acid AbC transporter
AYJ57_21740	ENOG4105E5Q	amino acid AbC transporter
AYJ57_21745	ENOG4105CDA	abc transporter atp-binding protein
AYJ57_21750	ENOG4105CYW	agmatinase
AYJ57_21760	ENOG4105C9A	Phoh family
AYJ57_21770	ENOG4105BZS	acriflavin resistance protein
AYJ57_21810	ENOG4105Y3E	Modulates RecA activity (By similarity)
AYJ57_21865	ENOG4107NQ8	LysR family Transcriptional regulator
AYJ57_21870	ENOG4108Z6Z	Transcriptional regulator
AYJ57_21905	ENOG4106NZI	LysR family Transcriptional regulator
AYJ57_21925	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AYJ57_21940	ENOG4107R11	Transcriptional regulator
AYJ57_21950	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_21955	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_21965	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
AYJ57_22005	ENOG4107RD7	Flagellar Motor Protein, MotA
AYJ57_22035	ENOG4105ER2	Ompa motb domain protein
AYJ57_22045	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ57_22065	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AYJ57_22075	ENOG4105CGA	flagellar basal-body rod protein FlgG
AYJ57_22080	ENOG4105KTQ	flagellar basal-body rod protein
AYJ57_22090	ENOG4105BZE	flagellar hook protein, FlgE
AYJ57_22105	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AYJ57_22110	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AYJ57_22125	ENOG4107W75	Flagellin
AYJ57_22135	ENOG4105IE4	repressor protein FlbT
AYJ57_22145	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AYJ57_22150	ENOG4105CN7	Flagellar biosynthetic protein FliP
AYJ57_22155	ENOG4105DD5	Flagellar motor switch protein
AYJ57_22165	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AYJ57_22190	ENOG4105BZ1	(ABC) transporter
AYJ57_22195	ENOG4105E0K	tonB-dependent siderophore receptor
AYJ57_22215	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AYJ57_22230	ENOG4107XKF	NMT1 THI5 Like Domain Protein
AYJ57_22240	ENOG4108IG5	Transcriptional regulator
AYJ57_22255	ENOG4105F0I	Aminotransferase
AYJ57_22260	ENOG4108WYP	Transcriptional regulator
AYJ57_22265	ENOG4105C8Y	Acetylornithine aminotransferase
AYJ57_22275	ENOG4105ETT	transcriptional Regulator, LysR family
AYJ57_22280	ENOG4105C26	Dehydrogenase
AYJ57_22285	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AYJ57_22300	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AYJ57_22305	ENOG4105WIU	sarcosine oxidase delta subunit
AYJ57_22310	ENOG4105DDR	sarcosine oxidase (Beta subunit)
AYJ57_22315	ENOG4105ECQ	AraC Family Transcriptional Regulator
AYJ57_22320	ENOG4106NZI	LysR family Transcriptional regulator
AYJ57_22335	ENOG4105WQI	isochorismatase
AYJ57_22340	ENOG4105E4F	Isochorismate synthase
AYJ57_22345	ENOG4108IJ9	(ABC) transporter
AYJ57_22350	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AYJ57_22355	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
AYJ57_22370	ENOG4105E0F	Histidine kinase
AYJ57_22375	ENOG4105D49	3-dehydroquinate synthase
AYJ57_22400	ENOG4105F8V	Hydrolase, tatD family
AYJ57_22410	ENOG4105DZG	Dehydrogenase
AYJ57_22425	ENOG4107RZC	phospholipase d
AYJ57_22430	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AYJ57_22440	ENOG4105C26	Dehydrogenase
AYJ57_22455	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AYJ57_22460	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
AYJ57_22465	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
AYJ57_22470	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AYJ57_22475	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AYJ57_22480	ENOG4105DDW	LysR family Transcriptional regulator
AYJ57_22485	ENOG4105C5I	Dehydrogenase
AYJ57_22500	ENOG4107SM8	Adenylate Guanylate cyclase
AYJ57_22510	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
AYJ57_22515	ENOG4108JPW	Aminotransferase
AYJ57_22520	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AYJ57_22525	ENOG4105CZK	Aspartate kinase
AYJ57_22530	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
AYJ57_22565	ENOG4108KS2	transglutaminase domain protein
AYJ57_22595	ENOG4108TJN	glycosyl transferase group 1
AYJ57_22620	ENOG4105D75	Capsular exopolysaccharide family
AYJ57_22645	ENOG4105D3Q	Sugar transferase
AYJ57_22655	ENOG4108JIR	Flagellum-specific ATP synthase
AYJ57_22660	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AYJ57_22665	ENOG4108ZC9	flagellar basal-body rod protein flgc
AYJ57_22670	ENOG4105X50	flagellar hook-basal body complex protein fliE
AYJ57_22675	ENOG4105VS8	Flagellar biosynthetic protein fliq
AYJ57_22685	ENOG4105D7B	Flagellar biosynthesis protein flha
AYJ57_22690	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AYJ57_22695	ENOG4105D00	flagellar biosynthetic protein flhB
AYJ57_22700	ENOG4105E9K	Isocitrate dehydrogenase
AYJ57_22715	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AYJ57_22720	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AYJ57_22740	ENOG4105ETE	Transcriptional regulator (LacI family
AYJ57_22750	ENOG4105CY0	Metallo-Beta-Lactamase
AYJ57_22760	ENOG4105C4Y	ABC transporter
AYJ57_22765	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_22770	ENOG4105VT2	5-hydroxyisourate hydrolase
AYJ57_22775	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ57_22785	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AYJ57_22795	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_22815	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ57_22825	ENOG4108MG3	formate dehydrogenase
AYJ57_22830	ENOG4105QAX	Iron-sulfur
AYJ57_22835	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AYJ57_22870	ENOG4105D1F	ATP-binding protein
AYJ57_22885	ENOG4105BZU	Histidine kinase
AYJ57_22890	ENOG4108IEG	Formate dehydrogenase Alpha subunit
AYJ57_22900	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AYJ57_22910	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AYJ57_22915	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
AYJ57_22920	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AYJ57_22945	ENOG4105CPQ	Dehydrogenase
AYJ57_22950	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_22960	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
AYJ57_22965	ENOG4107XBN	GntR Family Transcriptional Regulator
AYJ57_22970	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AYJ57_22975	ENOG4105DEI	Mannitol dehydrogenase
AYJ57_22985	ENOG4107QWE	)-transporter
AYJ57_22995	ENOG4106NZI	LysR family Transcriptional regulator
AYJ57_23000	ENOG4105RD8	TRAP dicarboxylate transporter
AYJ57_23010	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_23015	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AYJ57_23030	ENOG4107R11	Transcriptional regulator
AYJ57_23040	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_23045	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_23055	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
AYJ57_23085	ENOG4108JQ7	(ABC) transporter
AYJ57_23100	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_23135	ENOG4107QRS	glycosyltransferase group 2 family protein
AYJ57_23165	ENOG4105EXC	Acyl-transferase
AYJ57_23250	ENOG4105CHR	reductase
AYJ57_23275	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_23280	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_23295	ENOG4107QM2	Aldo Keto reductase
AYJ57_23310	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AYJ57_23330	ENOG4105CNM	Receptor
AYJ57_23345	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AYJ57_23360	ENOG4105C4R	Atp-dependent dna helicase
AYJ57_23375	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AYJ57_23390	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AYJ57_23395	ENOG4108IYU	L-aspartate oxidase
AYJ57_23400	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AYJ57_23415	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
AYJ57_23425	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_23450	ENOG4108JQ1	Dehydrogenase
AYJ57_23465	ENOG4105P4J	Allophanate hydrolase, subunit 1
AYJ57_23470	ENOG4105E7W	lamb ycsf family protein
AYJ57_23480	ENOG4105CHM	Aminotransferase
AYJ57_23485	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ57_23500	ENOG4105CKI	cobalamin synthesis protein
AYJ57_23535	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ57_23545	ENOG4105JSC	dimethylmenaquinone methyltransferase
AYJ57_23550	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
AYJ57_23555	ENOG4108JQ7	(ABC) transporter
AYJ57_23565	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_23570	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_23575	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_23595	ENOG4105CJ1	ABC, transporter
AYJ57_23610	ENOG4105C08	Histidine kinase
AYJ57_23615	ENOG4105ETX	regulatoR
AYJ57_23620	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
AYJ57_23625	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
AYJ57_23630	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
AYJ57_23635	ENOG4105Z85	coenzyme PQQ synthesis
AYJ57_23640	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AYJ57_23680	ENOG4105BZU	Histidine kinase
AYJ57_23710	ENOG4107QPD	alcohol dehydrogenase
AYJ57_23715	ENOG4105C4W	S-formylglutathione hydrolase
AYJ57_23725	ENOG4105DZG	Dehydrogenase
AYJ57_23730	ENOG4108U4V	Cytochrome c protein
AYJ57_23780	ENOG4105E2Y	ABC, transporter
AYJ57_23795	ENOG4105CAF	HipA N-terminal domain protein
AYJ57_23800	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AYJ57_23815	ENOG4108XM1	transcriptional regulator AsnC family
AYJ57_23840	ENOG4105EAD	ABC transporter
AYJ57_23845	ENOG4105E5Q	amino acid AbC transporter
AYJ57_23855	ENOG4105EAB	amino acid AbC transporter
AYJ57_23865	ENOG4108VVQ	metallophosphoesterase
AYJ57_23870	ENOG4105KME	endoribonuclease L-psp
AYJ57_23875	ENOG4105DV0	amidase (EC 3.5.1.4
AYJ57_23880	ENOG4105BZC	d-serine deaminase
AYJ57_23890	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AYJ57_23895	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AYJ57_23915	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_23920	ENOG4107XBN	GntR Family Transcriptional Regulator
AYJ57_23925	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AYJ57_23955	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AYJ57_23960	ENOG4105CHR	reductase
AYJ57_23965	ENOG4105F8C	transglutaminase domain-containing protein
AYJ57_23975	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_23980	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_23995	ENOG4105CPU	Monooxygenase
AYJ57_24000	ENOG4105CPU	Monooxygenase
AYJ57_24005	ENOG4108EVY	peptide transport periplasmic protein
AYJ57_24010	ENOG4108JQ7	(ABC) transporter
AYJ57_24015	ENOG4105C3U	ABC transporter
AYJ57_24020	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_24050	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AYJ57_24060	ENOG4108IY8	ABC, transporter
AYJ57_24065	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AYJ57_24075	ENOG4105DRR	Transcriptional regulator, GntR family
AYJ57_24085	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_24090	ENOG4105F38	ABC transporter, permease
AYJ57_24105	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_24130	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_24140	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_24145	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_24160	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AYJ57_24165	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
AYJ57_24175	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AYJ57_24220	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_24230	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
AYJ57_24240	ENOG4105E1J	oxidoreductase
AYJ57_24245	ENOG4108IGT	Dipeptidase
AYJ57_24250	ENOG4105C5I	Dehydrogenase
AYJ57_24255	ENOG4108HWW	ABC transporter
AYJ57_24265	ENOG4105EQ2	LysR family Transcriptional regulator
AYJ57_24270	ENOG4105F27	Major Facilitator
AYJ57_24310	ENOG4105CMJ	mandelate racemase muconate lactonizing
AYJ57_24315	ENOG4107YNJ	LysR family Transcriptional regulator
AYJ57_24320	ENOG4105EJC	lysr family transcriptional regulator
AYJ57_24355	ENOG4105C94	Transporter
AYJ57_24360	ENOG4108KTU	conserved protein with FAD NAD(P)-binding domain
AYJ57_24385	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AYJ57_24390	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AYJ57_24440	ENOG4105DUX	Transporter
AYJ57_24475	ENOG4107QJE	Chromosome Partitioning Protein
AYJ57_24490	ENOG4107HP6	Transcriptional regulator
AYJ57_24500	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AYJ57_24515	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AYJ57_24520	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_24530	ENOG4105C26	Dehydrogenase
AYJ57_24535	ENOG4105C01	Dihydroxy-acid dehydratase
AYJ57_24550	ENOG4105C2W	permease
AYJ57_24560	ENOG4105EQ0	Major Facilitator superfamily
AYJ57_24570	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
AYJ57_24590	ENOG41073TP	transcriptional regulator
AYJ57_24595	ENOG4107S2N	Type III effector Hrp-dependent
AYJ57_24600	ENOG4105C0A	alcohol dehydrogenase
AYJ57_24610	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
AYJ57_24620	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ57_24650	ENOG4105C2J	ABC transporter
AYJ57_24655	ENOG4105CNN	ABC, transporter
AYJ57_24690	ENOG4105CE4	GlcNAc 6-P deacetylase
AYJ57_24695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_24700	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AYJ57_24710	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AYJ57_24720	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AYJ57_24725	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AYJ57_24730	ENOG4105FDP	GntR family transcriptional regulator
AYJ57_24750	ENOG4105EHG	Permease protein
AYJ57_24755	ENOG4105E0A	ABC, transporter
AYJ57_24780	ENOG4105CWC	Acetylornithine deacetylase
AYJ57_24785	ENOG4108SZE	gCN5-related N-acetyltransferase
AYJ57_24790	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AYJ57_24795	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_24815	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_24820	ENOG4108JQ6	ABC transporter
AYJ57_24825	ENOG4108RYR	transcriptional regulator AsnC family
AYJ57_24830	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AYJ57_24835	ENOG41080HI	glycine oxidase
AYJ57_24840	ENOG4105RQF	LysR family Transcriptional regulator
AYJ57_24865	ENOG4105C26	Dehydrogenase
AYJ57_24870	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AYJ57_24880	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_24890	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ57_24895	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ57_24900	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ57_24905	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ57_24910	ENOG4107H6U	ABC transporter
AYJ57_24935	ENOG4105F9F	transposase
AYJ57_24940	ENOG4105FN4	Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond (By similarity)
AYJ57_24955	ENOG4105JHR	Alginate biosynthesis protein AlgX
AYJ57_24965	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
AYJ57_24970	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AYJ57_24980	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AYJ57_24990	ENOG4105KZJ	alginate biosynthesis protein Alg8
AYJ57_24995	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AYJ57_25020	ENOG4105D9P	serine threonine protein kinase
AYJ57_25035	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ57_25050	ENOG4105CD3	dihydroorotase
AYJ57_25080	ENOG4107STQ	Multicopper oxidase
AYJ57_25085	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
AYJ57_25090	ENOG4105DZ2	Transcriptional regulator
AYJ57_25110	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AYJ57_25215	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AYJ57_25220	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ57_25225	ENOG4105F38	ABC transporter, permease
AYJ57_25230	ENOG4105D38	putrescine abc transporter
AYJ57_25245	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AYJ57_25280	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AYJ57_25350	ENOG4107SBE	Glycosyl transferase (Group 1
AYJ57_25360	ENOG4105ECX	polysaccharide export
AYJ57_25435	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AYJ57_25440	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)