locus-tag	class	description
AYJ57_00010	COG2885	chlorophyll binding
AYJ57_00025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYJ57_00045	COG0440	acetolactate synthase activity
AYJ57_00055	COG0028	Belongs to the TPP enzyme family
AYJ57_00075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AYJ57_00085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_00100	COG4638	Rieske (2fe-2S)
AYJ57_00105	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AYJ57_00110	COG0028	Belongs to the TPP enzyme family
AYJ57_00115	COG1522	sequence-specific DNA binding
AYJ57_00165	COG3086	response to oxidative stress
AYJ57_00185	COG0716	FMN binding
AYJ57_00195	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AYJ57_00200	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AYJ57_00230	COG5420	small protein containing a coiled-coil domain
AYJ57_00260	COG1104	cysteine desulfurase activity
AYJ57_00280	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYJ57_00285	COG4149	molybdate abc transporter
AYJ57_00290	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYJ57_00305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AYJ57_00310	COG3604	Transcriptional regulator
AYJ57_00320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYJ57_00365	COG0583	DNA-binding transcription factor activity
AYJ57_00375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ57_00385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AYJ57_00390	COG4235	cytochrome complex assembly
AYJ57_00395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_00415	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ57_00415	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_00435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AYJ57_00435	COG1648	precorrin-2 dehydrogenase activity
AYJ57_00445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_00470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ57_00480	COG3811	Belongs to the UPF0386 family
AYJ57_00485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYJ57_00490	COG0415	Belongs to the DNA photolyase family
AYJ57_00500	COG0494	nUDIX hydrolase
AYJ57_00515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AYJ57_00530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AYJ57_00545	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AYJ57_00555	COG0166	Belongs to the GPI family
AYJ57_00580	COG3108	Peptidase M15
AYJ57_00590	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_00595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYJ57_00605	COG0431	NADPH-dependent FMN reductase
AYJ57_00615	COG2354	Protein conserved in bacteria
AYJ57_00625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYJ57_00655	COG0033	Phosphoglucomutase
AYJ57_00670	COG0297	glycogen (starch) synthase activity
AYJ57_00675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AYJ57_00680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AYJ57_00685	COG0058	SHG alpha-glucan phosphorylase activity
AYJ57_00690	COG0837	glucose binding
AYJ57_00695	COG2723	6-phospho-beta-galactosidase activity
AYJ57_00700	COG1609	Transcriptional regulator
AYJ57_00705	COG1653	transport
AYJ57_00710	COG1175	transmembrane transport
AYJ57_00715	COG0395	ABC-type sugar transport system, permease component
AYJ57_00720	COG0366	Alpha amylase catalytic
AYJ57_00725	COG3842	ATPase activity
AYJ57_00730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYJ57_00740	COG1024	Enoyl-CoA hydratase
AYJ57_00750	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYJ57_00775	COG1492	cobalamin metabolic process
AYJ57_00785	COG0538	isocitrate dehydrogenase activity
AYJ57_00800	COG2814	Major facilitator Superfamily
AYJ57_00815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AYJ57_00820	COG1960	acyl-CoA dehydrogenase activity
AYJ57_00825	COG0438	transferase activity, transferring glycosyl groups
AYJ57_00830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_00840	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AYJ57_00845	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AYJ57_00850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYJ57_00860	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYJ57_00875	COG2166	iron-sulfur cluster assembly
AYJ57_00880	COG0233	cytoplasmic translational termination
AYJ57_00885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYJ57_00890	COG0575	Belongs to the CDS family
AYJ57_00895	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AYJ57_00900	COG0750	zinc metalloprotease
AYJ57_00915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ57_00920	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_00925	COG3494	Protein of unknown function (DUF1009)
AYJ57_00930	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_00940	COG0433	COG0433 Predicted ATPase
AYJ57_00955	COG4166	transmembrane transport
AYJ57_00960	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_00970	COG1573	uracil-dna glycosylase
AYJ57_00980	COG2313	pseudouridylate synthase activity
AYJ57_00985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_00990	COG2130	NADP-dependent
AYJ57_01005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AYJ57_01010	COG2197	response regulator
AYJ57_01015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AYJ57_01020	COG0052	Belongs to the universal ribosomal protein uS2 family
AYJ57_01040	COG0745	RESPONSE REGULATOR receiver
AYJ57_01045	COG0704	Plays a role in the regulation of phosphate uptake
AYJ57_01050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYJ57_01055	COG0581	inorganic phosphate transmembrane transporter activity
AYJ57_01060	COG0573	inorganic phosphate transmembrane transporter activity
AYJ57_01070	COG5002	protein histidine kinase activity
AYJ57_01075	COG0626	cystathionine gamma-synthase activity
AYJ57_01090	COG0194	GDP metabolic process
AYJ57_01095	COG1561	YicC-like family, N-terminal region
AYJ57_01105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYJ57_01110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ57_01120	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AYJ57_01135	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AYJ57_01145	COG2133	pyrroloquinoline quinone binding
AYJ57_01150	COG0442	prolyl-tRNA aminoacylation
AYJ57_01200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ57_01215	COG1278	Cold shock
AYJ57_01220	COG0259	pyridoxamine-phosphate oxidase activity
AYJ57_01225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYJ57_01235	COG0702	epimerase
AYJ57_01240	COG1733	regulation of RNA biosynthetic process
AYJ57_01255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYJ57_01270	COG2032	superoxide dismutase activity
AYJ57_01275	COG0517	IMP dehydrogenase activity
AYJ57_01275	COG1994	Peptidase M50
AYJ57_01280	COG1410	methionine synthase
AYJ57_01280	COG0646	methionine synthase
AYJ57_01295	COG5012	cobalamin binding
AYJ57_01315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYJ57_01320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AYJ57_01325	COG0134	indole-3-glycerol-phosphate synthase activity
AYJ57_01335	COG0303	'Molybdopterin
AYJ57_01340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYJ57_01345	COG0658	competence protein
AYJ57_01345	COG2333	competence protein COMEC
AYJ57_01350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ57_01360	COG1024	Enoyl-CoA hydratase
AYJ57_01370	COG3088	subunit of a heme lyase
AYJ57_01375	COG1138	Cytochrome C-type biogenesis protein
AYJ57_01385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AYJ57_01390	COG3743	rRNA binding
AYJ57_01390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AYJ57_01425	COG1238	metal cluster binding
AYJ57_01450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AYJ57_01455	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AYJ57_01490	COG2059	Chromate
AYJ57_01500	COG0114	fumarate hydratase activity
AYJ57_01520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYJ57_01560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_01565	COG0642	Histidine kinase
AYJ57_01570	COG0745	RESPONSE REGULATOR receiver
AYJ57_01575	COG1376	ErfK ybiS ycfS ynhG family protein
AYJ57_01585	COG1070	Carbohydrate kinase
AYJ57_01610	COG1175	transmembrane transport
AYJ57_01625	COG0546	phosphoglycolate phosphatase activity
AYJ57_01635	COG0805	protein transport
AYJ57_01640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYJ57_01645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYJ57_01650	COG2378	regulation of single-species biofilm formation
AYJ57_01665	COG0477	Major facilitator Superfamily
AYJ57_01675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYJ57_01685	COG0360	Binds together with S18 to 16S ribosomal RNA
AYJ57_01690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AYJ57_01695	COG0359	binds to the 23S rRNA
AYJ57_01705	COG0544	peptidyl-prolyl cis-trans isomerase activity
AYJ57_01710	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYJ57_01735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYJ57_01745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYJ57_01750	COG5265	(ABC) transporter
AYJ57_01775	COG3588	fructose-bisphosphate aldolase
AYJ57_01790	COG0785	Cytochrome C biogenesis protein
AYJ57_01795	COG1530	ribonuclease E activity
AYJ57_01805	COG2084	Dehydrogenase
AYJ57_01820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYJ57_01825	COG1923	regulation of RNA biosynthetic process
AYJ57_01830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ57_01835	COG0569	domain protein
AYJ57_01840	COG2204	response regulator
AYJ57_01845	COG5000	phosphorelay sensor kinase activity
AYJ57_01850	COG2204	response regulator
AYJ57_01855	COG3852	Histidine kinase
AYJ57_01860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ57_01865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AYJ57_01865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AYJ57_01870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYJ57_01875	COG1546	Belongs to the CinA family
AYJ57_01880	COG2867	negative regulation of translational initiation
AYJ57_01895	COG3909	cytochrome
AYJ57_01900	COG2010	Cytochrome c
AYJ57_01910	COG2391	methyltransferase activity
AYJ57_01925	COG0785	Cytochrome C biogenesis protein
AYJ57_01950	COG3258	Cytochrome c
AYJ57_01955	COG0737	Belongs to the 5'-nucleotidase family
AYJ57_01960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AYJ57_01975	COG0156	8-amino-7-oxononanoate synthase activity
AYJ57_01980	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AYJ57_01990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ57_01995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AYJ57_02005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYJ57_02010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AYJ57_02025	COG0482	sulfurtransferase activity
AYJ57_02040	COG2204	response regulator
AYJ57_02050	COG0047	phosphoribosylformylglycinamidine synthase activity
AYJ57_02055	COG1063	alcohol dehydrogenase
AYJ57_02060	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AYJ57_02070	COG2326	polyphosphate kinase activity
AYJ57_02080	COG0438	transferase activity, transferring glycosyl groups
AYJ57_02095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AYJ57_02100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_02110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AYJ57_02115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AYJ57_02125	COG4974	Belongs to the 'phage' integrase family
AYJ57_02130	COG0528	UMP kinase activity
AYJ57_02135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AYJ57_02150	COG1858	cytochrome C peroxidase
AYJ57_02155	COG0741	lytic transglycosylase activity
AYJ57_02160	COG0629	single-stranded DNA binding
AYJ57_02170	COG4536	flavin adenine dinucleotide binding
AYJ57_02190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYJ57_02195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AYJ57_02205	COG2205	protein histidine kinase activity
AYJ57_02210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ57_02220	COG0745	RESPONSE REGULATOR receiver
AYJ57_02265	COG0714	Associated with various cellular activities
AYJ57_02275	COG3119	arylsulfatase activity
AYJ57_02290	COG0753	catalase activity
AYJ57_02320	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ57_02320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ57_02325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AYJ57_02330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AYJ57_02340	COG0697	spore germination
AYJ57_02350	COG0840	transmembrane signaling receptor activity
AYJ57_02350	COG0840	transmembrane signaling receptor activity
AYJ57_02390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AYJ57_02420	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYJ57_02435	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AYJ57_02440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYJ57_02460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYJ57_02475	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AYJ57_02480	COG1612	heme a metabolic process
AYJ57_02490	COG0454	-acetyltransferase
AYJ57_02490	COG0456	acetyltransferase
AYJ57_02495	COG0352	thiamine-phosphate diphosphorylase activity
AYJ57_02520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AYJ57_02525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AYJ57_02530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AYJ57_02555	COG2151	metal-sulfur cluster biosynthetic enzyme
AYJ57_02565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYJ57_02570	COG0316	Belongs to the HesB IscA family
AYJ57_02575	COG0149	triose-phosphate isomerase activity
AYJ57_02585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_02590	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYJ57_02595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_02620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AYJ57_02630	COG1007	ATP synthesis coupled electron transport
AYJ57_02645	COG0713	ATP synthesis coupled electron transport
AYJ57_02665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AYJ57_02720	COG0649	NAD binding
AYJ57_02725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ57_02730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ57_02740	COG1024	Enoyl-CoA hydratase
AYJ57_02740	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_02750	COG0625	glutathione transferase activity
AYJ57_02760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYJ57_02765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ57_02775	COG1960	acyl-CoA dehydrogenase activity
AYJ57_02790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ57_02795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYJ57_02800	COG0542	response to heat
AYJ57_02805	COG0513	Belongs to the DEAD box helicase family
AYJ57_02810	COG1764	response to oxidative stress
AYJ57_02820	COG1522	sequence-specific DNA binding
AYJ57_02830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ57_02835	COG0175	sulfate reduction
AYJ57_02850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_02865	COG3181	Tripartite tricarboxylate transporter family receptor
AYJ57_02885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AYJ57_02895	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AYJ57_02915	COG0546	phosphoglycolate phosphatase activity
AYJ57_02920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AYJ57_02930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYJ57_02945	COG0719	Fe-S assembly protein
AYJ57_02950	COG0396	ATPase activity
AYJ57_02960	COG0393	Putative heavy-metal-binding
AYJ57_02970	COG0719	Fe-S assembly protein
AYJ57_02980	COG1959	2 iron, 2 sulfur cluster binding
AYJ57_02985	COG2945	thiolester hydrolase activity
AYJ57_03000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ57_03025	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AYJ57_03035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ57_03040	COG0739	heme binding
AYJ57_03075	COG2814	Major facilitator Superfamily
AYJ57_03085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ57_03090	COG0215	cysteine-tRNA ligase activity
AYJ57_03105	COG2890	protein-(glutamine-N5) methyltransferase activity
AYJ57_03110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AYJ57_03120	COG0010	Belongs to the arginase family
AYJ57_03125	COG1473	amidohydrolase
AYJ57_03130	COG1473	amidohydrolase
AYJ57_03135	COG3956	TIGRFAM MazG family protein
AYJ57_03140	COG1840	ABC-type Fe3 transport system, periplasmic component
AYJ57_03145	COG3454	Phosphonate metabolism
AYJ57_03150	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AYJ57_03160	COG4778	phosphonate C-P lyase system protein PhnL
AYJ57_03165	COG4107	phosphonate C-P lyase system protein PhnK
AYJ57_03170	COG3627	carbon phosphorus lyase activity
AYJ57_03180	COG3626	phosphonate metabolism
AYJ57_03190	COG3624	Phosphonate C-P lyase system protein PhnG
AYJ57_03195	COG2188	Transcriptional regulator
AYJ57_03200	COG3454	Phosphonate metabolism
AYJ57_03205	COG1879	ABC-type sugar transport system periplasmic component
AYJ57_03210	COG0840	transmembrane signaling receptor activity
AYJ57_03220	COG3639	organic phosphonate transmembrane transporter activity
AYJ57_03230	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AYJ57_03235	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AYJ57_03255	COG0352	thiamine-phosphate diphosphorylase activity
AYJ57_03265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AYJ57_03270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYJ57_03295	COG1846	Transcriptional regulator
AYJ57_03300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ57_03315	COG2943	transferase activity, transferring hexosyl groups
AYJ57_03320	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AYJ57_03335	COG0154	amidase activity
AYJ57_03340	COG0444	Belongs to the ABC transporter superfamily
AYJ57_03345	COG4608	Belongs to the ABC transporter superfamily
AYJ57_03350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_03390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYJ57_03400	COG1414	Transcriptional regulator
AYJ57_03415	COG0330	HflC and HflK could
AYJ57_03420	COG0330	HflC and HflK could
AYJ57_03430	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AYJ57_03435	COG1760	l-serine dehydratase
AYJ57_03445	COG0456	acetyltransferase
AYJ57_03480	COG0375	protein maturation
AYJ57_03540	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYJ57_03550	COG4191	Histidine kinase
AYJ57_03570	COG4603	Belongs to the binding-protein-dependent transport system permease family
AYJ57_03580	COG0402	S-adenosylhomocysteine deaminase activity
AYJ57_03595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYJ57_03635	COG1136	(ABC) transporter
AYJ57_03645	COG2353	YceI-like domain
AYJ57_03650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AYJ57_03660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AYJ57_03670	COG1132	(ABC) transporter
AYJ57_03690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AYJ57_03710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYJ57_03725	COG0405	Gamma-glutamyltransferase
AYJ57_03750	COG0745	RESPONSE REGULATOR receiver
AYJ57_03755	COG1396	sequence-specific DNA binding
AYJ57_03755	COG3800	Transcriptional regulator
AYJ57_03765	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYJ57_03780	COG0410	ABC transporter
AYJ57_03785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ57_03800	COG0439	Biotin carboxylase
AYJ57_03805	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AYJ57_03835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AYJ57_03840	COG0740	serine-type endopeptidase activity
AYJ57_03845	COG1230	cation diffusion facilitator family transporter
AYJ57_03870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ57_03875	COG1121	(ABC) transporter
AYJ57_03880	COG0735	belongs to the Fur family
AYJ57_03890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AYJ57_03895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ57_03900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ57_03905	COG1120	ATPase activity
AYJ57_03915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AYJ57_03920	COG1984	allophanate hydrolase subunit 2
AYJ57_03925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AYJ57_03935	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AYJ57_03940	COG1530	ribonuclease E activity
AYJ57_03950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AYJ57_03955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYJ57_03995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYJ57_04010	COG2954	triphosphatase activity
AYJ57_04015	COG1192	Involved in chromosome partitioning
AYJ57_04035	COG0358	DNA primase activity
AYJ57_04040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYJ57_04060	COG0729	surface antigen
AYJ57_04075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AYJ57_04080	COG0830	nickel cation binding
AYJ57_04085	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AYJ57_04095	COG0804	urea catabolic process
AYJ57_04105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYJ57_04105	COG2010	Cytochrome c
AYJ57_04120	COG0832	Belongs to the urease beta subunit family
AYJ57_04125	COG0831	urea catabolic process
AYJ57_04130	COG0829	nickel cation binding
AYJ57_04135	COG1720	tRNA m6t6A37 methyltransferase activity
AYJ57_04140	COG0800	Aldolase
AYJ57_04145	COG3734	2-keto-3-deoxy-galactonokinase
AYJ57_04165	COG2307	Protein conserved in bacteria
AYJ57_04165	COG2308	Evidence 4 Homologs of previously reported genes of
AYJ57_04175	COG4221	oxidoreductase activity
AYJ57_04185	COG0432	Pfam Uncharacterised protein family UPF0047
AYJ57_04190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AYJ57_04195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ57_04195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ57_04200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYJ57_04235	COG4166	transmembrane transport
AYJ57_04240	COG4174	ABC transporter (Permease)
AYJ57_04245	COG4239	(ABC) transporter, permease
AYJ57_04250	COG4172	Belongs to the ABC transporter superfamily
AYJ57_04255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYJ57_04260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYJ57_04265	COG5507	3-demethylubiquinone-9 3-methyltransferase
AYJ57_04295	COG2010	Cytochrome c
AYJ57_04300	COG0583	DNA-binding transcription factor activity
AYJ57_04305	COG0348	domain, Protein
AYJ57_04335	COG1522	sequence-specific DNA binding
AYJ57_04340	COG0686	Belongs to the AlaDH PNT family
AYJ57_04345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AYJ57_04350	COG1970	mechanosensitive ion channel activity
AYJ57_04385	COG0768	penicillin binding
AYJ57_04390	COG0772	Belongs to the SEDS family
AYJ57_04395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_04405	COG0659	secondary active sulfate transmembrane transporter activity
AYJ57_04415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AYJ57_04420	COG1280	lysine exporter protein (LysE YggA)
AYJ57_04430	COG0534	Mate efflux family protein
AYJ57_04460	COG0625	glutathione transferase activity
AYJ57_04490	COG0813	purine-nucleoside phosphorylase activity
AYJ57_04500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AYJ57_04535	COG2030	dehydratase
AYJ57_04550	COG2301	Belongs to the HpcH HpaI aldolase family
AYJ57_04560	COG1732	Glycine betaine
AYJ57_04565	COG1174	glycine betaine transport
AYJ57_04570	COG1125	glycine betaine transport
AYJ57_04575	COG1174	glycine betaine transport
AYJ57_04580	COG0039	L-malate dehydrogenase activity
AYJ57_04585	COG0045	succinate-CoA ligase (ADP-forming) activity
AYJ57_04590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYJ57_04595	COG0567	Dehydrogenase, E1 component
AYJ57_04600	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ57_04640	COG2884	Cell division ATP-binding protein ftsE
AYJ57_04650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_04655	COG1116	anion transmembrane transporter activity
AYJ57_04665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYJ57_04680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYJ57_04690	COG1196	nuclear chromosome segregation
AYJ57_04690	COG0741	lytic transglycosylase activity
AYJ57_04690	COG0739	heme binding
AYJ57_04700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AYJ57_04705	COG0602	queuosine metabolic process
AYJ57_04710	COG0720	synthase
AYJ57_04715	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AYJ57_04720	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AYJ57_04725	COG0142	geranyltranstransferase activity
AYJ57_04730	COG1722	exodeoxyribonuclease VII activity
AYJ57_04735	COG0123	including yeast histone deacetylase and acetoin utilization protein
AYJ57_04740	COG0745	RESPONSE REGULATOR receiver
AYJ57_04745	COG1846	Transcriptional regulator
AYJ57_04750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYJ57_04765	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_04775	COG3842	ATPase activity
AYJ57_04795	COG0745	RESPONSE REGULATOR receiver
AYJ57_04805	COG1185	polyribonucleotide nucleotidyltransferase activity
AYJ57_04810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AYJ57_04830	COG2835	tetraacyldisaccharide 4'-kinase activity
AYJ57_04850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_04855	COG0708	Exodeoxyribonuclease III
AYJ57_04865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AYJ57_04870	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AYJ57_04875	COG4535	Mg2 and Co2 transporter CorC
AYJ57_04880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AYJ57_04885	COG1702	phosphate starvation-inducible protein PhoH
AYJ57_04895	COG2885	chlorophyll binding
AYJ57_04900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AYJ57_04910	COG2871	sodium ion transport
AYJ57_04915	COG0735	belongs to the Fur family
AYJ57_04920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ57_04925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYJ57_04930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYJ57_04940	COG1335	isochorismatase
AYJ57_04945	COG1566	PFAM secretion protein HlyD family protein
AYJ57_04965	COG1522	sequence-specific DNA binding
AYJ57_04985	COG0483	inositol monophosphate 1-phosphatase activity
AYJ57_05000	COG3119	arylsulfatase activity
AYJ57_05005	COG0583	DNA-binding transcription factor activity
AYJ57_05045	COG0346	lactoylglutathione lyase activity
AYJ57_05060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AYJ57_05090	COG0187	DNA topoisomerase II activity
AYJ57_05115	COG3237	CsbD-like
AYJ57_05135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_05165	COG0556	nucleotide-excision repair
AYJ57_05185	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AYJ57_05195	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AYJ57_05235	COG1294	oxidase, subunit
AYJ57_05240	COG1271	oxidase subunit
AYJ57_05245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AYJ57_05250	COG4988	ABC transporter
AYJ57_05270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ57_05275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ57_05290	COG4598	ABC transporter
AYJ57_05295	COG0765	amino acid transport
AYJ57_05305	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AYJ57_05310	COG0277	FAD linked oxidase domain protein
AYJ57_05315	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AYJ57_05325	COG2986	histidine ammonia-lyase
AYJ57_05330	COG1228	amidohydrolase
AYJ57_05340	COG0628	permease
AYJ57_05350	COG1295	ribonuclease BN
AYJ57_05360	COG1597	lipid kinase activity
AYJ57_05385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYJ57_05395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYJ57_05405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYJ57_05425	COG1968	undecaprenyl-diphosphatase activity
AYJ57_05430	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AYJ57_05435	COG0799	negative regulation of ribosome biogenesis
AYJ57_05440	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_05465	COG2897	thiosulfate sulfurtransferase activity
AYJ57_05470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AYJ57_05480	COG3257	ureidoglycine aminohydrolase activity
AYJ57_05485	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AYJ57_05515	COG2951	lytic endotransglycosylase activity
AYJ57_05540	COG0235	Class ii aldolase
AYJ57_05545	COG2267	carboxylic ester hydrolase activity
AYJ57_05550	COG0251	oxidation-reduction process
AYJ57_05555	COG1335	isochorismatase
AYJ57_05560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_05575	COG0438	transferase activity, transferring glycosyl groups
AYJ57_05580	COG0438	transferase activity, transferring glycosyl groups
AYJ57_05590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AYJ57_05610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_05620	COG0589	response to stress
AYJ57_05640	COG4974	Belongs to the 'phage' integrase family
AYJ57_05645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AYJ57_05650	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AYJ57_05655	COG0840	transmembrane signaling receptor activity
AYJ57_05660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AYJ57_05665	COG4143	(ABC) transporter
AYJ57_05675	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AYJ57_05700	COG2824	Alkylphosphonate utilization operon protein PhnA
AYJ57_05705	COG1183	phosphatidylcholine synthase activity
AYJ57_05720	COG0459	protein refolding
AYJ57_05730	COG0697	spore germination
AYJ57_05750	COG0765	amino acid transport
AYJ57_05760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYJ57_05765	COG0756	dUTP diphosphatase activity
AYJ57_05770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYJ57_05780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYJ57_05785	COG0606	chelatase, subunit chli
AYJ57_05790	COG0657	acetylesterase activity
AYJ57_05800	COG0792	nuclease activity
AYJ57_05805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AYJ57_05815	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AYJ57_05820	COG1278	Cold shock
AYJ57_05825	COG0513	Belongs to the DEAD box helicase family
AYJ57_05835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ57_05845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_05855	COG0180	Tryptophanyl-tRNA synthetase
AYJ57_05870	COG2255	four-way junction helicase activity
AYJ57_05875	COG0632	four-way junction helicase activity
AYJ57_05905	COG0662	Cupin 2, conserved barrel domain protein
AYJ57_05910	COG2391	methyltransferase activity
AYJ57_05915	COG0408	coproporphyrinogen oxidase activity
AYJ57_05920	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_05925	COG2813	Specifically methylates the guanine in position
AYJ57_05930	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AYJ57_05940	COG1686	Belongs to the peptidase S11 family
AYJ57_05945	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYJ57_05970	COG1047	Peptidyl-prolyl cis-trans
AYJ57_05985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AYJ57_06000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYJ57_06005	COG0640	Transcriptional regulator
AYJ57_06010	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ57_06015	COG1132	(ABC) transporter
AYJ57_06030	COG0300	oxidoreductase activity
AYJ57_06035	COG3806	Anti-sigma factor
AYJ57_06040	COG1595	DNA-templated transcription, initiation
AYJ57_06055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYJ57_06065	COG2135	peptidase activity
AYJ57_06075	COG0590	tRNA wobble adenosine to inosine editing
AYJ57_06080	COG1187	pseudouridine synthase activity
AYJ57_06100	COG3853	Toxic anion resistance protein (TelA)
AYJ57_06130	COG1490	D-aminoacyl-tRNA deacylase activity
AYJ57_06150	COG4191	Histidine kinase
AYJ57_06165	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AYJ57_06170	COG0594	ribonuclease P activity
AYJ57_06175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AYJ57_06180	COG0037	tRNA processing
AYJ57_06190	COG0706	membrane insertase activity
AYJ57_06200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AYJ57_06205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYJ57_06215	COG2062	phosphohistidine phosphatase, SixA
AYJ57_06220	COG1126	abc transporter atp-binding protein
AYJ57_06225	COG0765	amino acid transport
AYJ57_06230	COG4597	amino acid ABC transporter
AYJ57_06235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ57_06245	COG0546	phosphoglycolate phosphatase activity
AYJ57_06250	COG0564	pseudouridine synthase activity
AYJ57_06260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYJ57_06265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYJ57_06270	COG0560	Phosphoserine phosphatase
AYJ57_06285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AYJ57_06315	COG2197	response regulator
AYJ57_06335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ57_06345	COG2124	cytochrome p450
AYJ57_06350	COG2096	Adenosyltransferase
AYJ57_06360	COG0300	oxidoreductase activity
AYJ57_06370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYJ57_06400	COG2192	nodulation
AYJ57_06410	COG1573	uracil-dna glycosylase
AYJ57_06420	COG3191	aminopeptidase activity
AYJ57_06450	COG2816	NAD+ diphosphatase activity
AYJ57_06455	COG3454	Phosphonate metabolism
AYJ57_06460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYJ57_06465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYJ57_06470	COG0039	L-malate dehydrogenase activity
AYJ57_06485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AYJ57_06490	COG0745	RESPONSE REGULATOR receiver
AYJ57_06495	COG2205	protein histidine kinase activity
AYJ57_06505	COG1660	Displays ATPase and GTPase activities
AYJ57_06515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYJ57_06525	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_06555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYJ57_06560	COG1177	transmembrane transport
AYJ57_06565	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_06570	COG3842	ATPase activity
AYJ57_06585	COG4638	Rieske (2fe-2S)
AYJ57_06600	COG0469	pyruvate kinase activity
AYJ57_06610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AYJ57_06615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AYJ57_06620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AYJ57_06640	COG0495	leucyl-tRNA aminoacylation
AYJ57_06645	COG0438	transferase activity, transferring glycosyl groups
AYJ57_06660	COG0457	Tetratricopeptide repeat
AYJ57_06665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AYJ57_06670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_06675	COG0196	riboflavin kinase activity
AYJ57_06680	COG2983	Belongs to the UPF0260 family
AYJ57_06705	COG1674	ftsk spoiiie
AYJ57_06710	COG0436	Aminotransferase
AYJ57_06720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_06730	COG0557	exoribonuclease II activity
AYJ57_06735	COG2951	lytic endotransglycosylase activity
AYJ57_06745	COG1051	belongs to the nudix hydrolase family
AYJ57_06750	COG0793	Belongs to the peptidase S41A family
AYJ57_06760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AYJ57_06765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_06805	COG1872	DUF167
AYJ57_06810	COG0778	Nitroreductase
AYJ57_06860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AYJ57_06865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYJ57_06870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYJ57_06880	COG0411	ABC transporter
AYJ57_06890	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYJ57_06905	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYJ57_06910	COG4149	molybdate abc transporter
AYJ57_06915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYJ57_06950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AYJ57_06955	COG0285	dihydrofolate synthase activity
AYJ57_06960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYJ57_06965	COG2271	Major facilitator Superfamily
AYJ57_06970	COG0596	Alpha beta hydrolase
AYJ57_06970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ57_06970	COG2226	methyltransferase
AYJ57_06980	COG1671	Belongs to the UPF0178 family
AYJ57_06985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AYJ57_07000	COG1131	(ABC) transporter
AYJ57_07025	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_07035	COG0714	Associated with various cellular activities
AYJ57_07070	COG0277	FAD linked oxidase domain protein
AYJ57_07075	COG0277	FAD linked oxidase domain protein
AYJ57_07080	COG0247	lactate metabolic process
AYJ57_07085	COG3591	Belongs to the peptidase S1B family
AYJ57_07095	COG0071	Belongs to the small heat shock protein (HSP20) family
AYJ57_07105	COG0604	alcohol dehydrogenase
AYJ57_07105	COG3321	synthase
AYJ57_07110	COG0583	DNA-binding transcription factor activity
AYJ57_07130	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_07145	COG3152	Membrane
AYJ57_07160	COG0437	4 iron, 4 sulfur cluster binding
AYJ57_07165	COG0243	molybdopterin cofactor binding
AYJ57_07180	COG0438	transferase activity, transferring glycosyl groups
AYJ57_07210	COG0673	inositol 2-dehydrogenase activity
AYJ57_07235	COG0489	protein tyrosine kinase activity
AYJ57_07275	COG0438	transferase activity, transferring glycosyl groups
AYJ57_07285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ57_07315	COG0517	IMP dehydrogenase activity
AYJ57_07315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYJ57_07320	COG1346	cytolysis
AYJ57_07325	COG1380	Effector of murein hydrolase LrgA
AYJ57_07350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AYJ57_07355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ57_07385	COG1115	amino acid carrier protein
AYJ57_07395	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AYJ57_07405	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AYJ57_07425	COG1999	signal sequence binding
AYJ57_07440	COG0802	atpase or kinase
AYJ57_07445	COG3178	'Phosphotransferase
AYJ57_07450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYJ57_07455	COG2887	Belongs to the helicase family. UvrD subfamily
AYJ57_07475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AYJ57_07480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AYJ57_07500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYJ57_07505	COG1301	dicarboxylic acid transport
AYJ57_07520	COG1040	competence protein
AYJ57_07555	COG3034	peptidoglycan biosynthetic process
AYJ57_07560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AYJ57_07565	COG1132	(ABC) transporter
AYJ57_07570	COG1132	(ABC) transporter
AYJ57_07580	COG0617	tRNA 3'-terminal CCA addition
AYJ57_07585	COG0494	nUDIX hydrolase
AYJ57_07590	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AYJ57_07600	COG0745	RESPONSE REGULATOR receiver
AYJ57_07610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYJ57_07620	COG0137	argininosuccinate synthase activity
AYJ57_07640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYJ57_07645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_07650	COG0281	malic enzyme
AYJ57_07650	COG0280	phosphate acetyltransferase
AYJ57_07655	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AYJ57_07660	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AYJ57_07665	COG1420	regulation of RNA biosynthetic process
AYJ57_07670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AYJ57_07675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AYJ57_07680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYJ57_07685	COG1475	DNA binding
AYJ57_07690	COG1192	Involved in chromosome partitioning
AYJ57_07695	COG0357	Ribosomal RNA small subunit methyltransferase G
AYJ57_07700	COG0445	tRNA wobble uridine modification
AYJ57_07705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AYJ57_07710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AYJ57_07715	COG0424	maF-like protein
AYJ57_07720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AYJ57_07725	COG0237	dephospho-CoA kinase activity
AYJ57_07730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYJ57_07735	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AYJ57_07740	COG3030	protein affecting phage T7 exclusion by the F plasmid
AYJ57_07760	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AYJ57_07765	COG3474	cytochrome
AYJ57_07770	COG1596	polysaccharide export
AYJ57_07775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYJ57_07785	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ57_07820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AYJ57_07825	COG2226	methyltransferase
AYJ57_07830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AYJ57_07845	COG0268	Binds directly to 16S ribosomal RNA
AYJ57_07850	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AYJ57_07855	COG0592	DNA-directed DNA polymerase activity
AYJ57_07860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AYJ57_07865	COG0187	DNA topoisomerase II activity
AYJ57_07920	COG0601	transmembrane transport
AYJ57_07925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_07930	COG4172	Belongs to the ABC transporter superfamily
AYJ57_07935	COG1309	transcriptional regulator
AYJ57_07940	COG0604	alcohol dehydrogenase
AYJ57_07950	COG0697	spore germination
AYJ57_07955	COG0473	3-isopropylmalate dehydrogenase activity
AYJ57_07970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYJ57_07980	COG0066	3-isopropylmalate dehydratase activity
AYJ57_07995	COG0183	Belongs to the thiolase family
AYJ57_08005	COG5002	protein histidine kinase activity
AYJ57_08005	COG2205	protein histidine kinase activity
AYJ57_08005	COG0784	Response regulator, receiver
AYJ57_08010	COG3022	response to hydroperoxide
AYJ57_08015	COG0514	ATP-dependent DNA helicase (RecQ)
AYJ57_08025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AYJ57_08035	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AYJ57_08060	COG0019	diaminopimelate decarboxylase activity
AYJ57_08080	COG0165	Argininosuccinate lyase
AYJ57_08085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ57_08100	COG0287	Prephenate dehydrogenase
AYJ57_08105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AYJ57_08110	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AYJ57_08115	COG1335	isochorismatase
AYJ57_08125	COG1338	Plays a role in the flagellum-specific transport system
AYJ57_08130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYJ57_08140	COG1766	The M ring may be actively involved in energy transduction
AYJ57_08160	COG3118	belongs to the thioredoxin family
AYJ57_08165	COG1376	ErfK ybiS ycfS ynhG family protein
AYJ57_08180	COG4181	ATPase activity
AYJ57_08190	COG0483	inositol monophosphate 1-phosphatase activity
AYJ57_08195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AYJ57_08195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AYJ57_08200	COG0509	glycine decarboxylation via glycine cleavage system
AYJ57_08205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_08210	COG1959	2 iron, 2 sulfur cluster binding
AYJ57_08220	COG4325	translation initiation factor activity
AYJ57_08225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ57_08250	COG3128	pkhd-type hydroxylase
AYJ57_08275	COG3046	protein related to deoxyribodipyrimidine photolyase
AYJ57_08295	COG3842	ATPase activity
AYJ57_08305	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_08320	COG1648	precorrin-2 dehydrogenase activity
AYJ57_08320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AYJ57_08325	COG0243	molybdopterin cofactor binding
AYJ57_08330	COG2146	nitrite reductase [NAD(P)H] activity
AYJ57_08335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ57_08340	COG1116	anion transmembrane transporter activity
AYJ57_08345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_08350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ57_08355	COG1116	anion transmembrane transporter activity
AYJ57_08355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ57_08360	COG3707	response regulator
AYJ57_08380	COG3842	ATPase activity
AYJ57_08385	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_08390	COG1177	transmembrane transport
AYJ57_08395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_08400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYJ57_08405	COG0004	ammonium transporteR
AYJ57_08410	COG0347	Belongs to the P(II) protein family
AYJ57_08415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AYJ57_08420	COG0284	orotidine-5'-phosphate decarboxylase activity
AYJ57_08450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYJ57_08465	COG1322	Protein conserved in bacteria
AYJ57_08470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYJ57_08490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYJ57_08490	COG2169	Transcriptional regulator
AYJ57_08495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYJ57_08500	COG2186	Transcriptional regulator
AYJ57_08505	COG0314	molybdopterin synthase activity
AYJ57_08515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYJ57_08520	COG1381	Involved in DNA repair and RecF pathway recombination
AYJ57_08535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AYJ57_08540	COG0697	spore germination
AYJ57_08545	COG0571	ribonuclease III activity
AYJ57_08550	COG0681	Belongs to the peptidase S26 family
AYJ57_08555	COG0736	holo-[acyl-carrier-protein] synthase activity
AYJ57_08560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYJ57_08570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYJ57_08580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYJ57_08590	COG1238	metal cluster binding
AYJ57_08595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AYJ57_08615	COG0328	RNA-DNA hybrid ribonuclease activity
AYJ57_08620	COG2860	membrane
AYJ57_08625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYJ57_08630	COG0242	peptide deformylase activity
AYJ57_08635	COG0242	peptide deformylase activity
AYJ57_08640	COG0242	peptide deformylase activity
AYJ57_08645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYJ57_08655	COG0435	Glutathione S-transferase
AYJ57_08675	COG0154	amidase activity
AYJ57_08680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ57_08690	COG4221	oxidoreductase activity
AYJ57_08695	COG1024	Enoyl-CoA hydratase
AYJ57_08700	COG0840	transmembrane signaling receptor activity
AYJ57_08710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AYJ57_08730	COG2171	N-acyltransferase activity
AYJ57_08755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYJ57_08780	COG0288	reversible hydration of carbon dioxide
AYJ57_08790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AYJ57_08795	COG0791	NLP P60 protein
AYJ57_08815	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AYJ57_08820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_08825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYJ57_08830	COG0659	secondary active sulfate transmembrane transporter activity
AYJ57_08840	COG0254	rRNA binding
AYJ57_08845	COG0335	large ribosomal subunit rRNA binding
AYJ57_08850	COG0336	Belongs to the RNA methyltransferase TrmD family
AYJ57_08860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AYJ57_08870	COG0228	four-way junction DNA binding
AYJ57_08900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYJ57_08925	COG0356	it plays a direct role in the translocation of protons across the membrane
AYJ57_08930	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AYJ57_08935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYJ57_08940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYJ57_08945	COG0489	protein tyrosine kinase activity
AYJ57_08945	COG2151	metal-sulfur cluster biosynthetic enzyme
AYJ57_08970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AYJ57_08975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AYJ57_08980	COG0747	negative chemotaxis
AYJ57_08985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_08995	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AYJ57_09020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ57_09035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AYJ57_09040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AYJ57_09045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AYJ57_09050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AYJ57_09075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AYJ57_09090	COG0540	Belongs to the ATCase OTCase family
AYJ57_09095	COG0742	ribosomal rna small subunit methyltransferase
AYJ57_09105	COG0678	peroxiredoxin activity
AYJ57_09110	COG2154	pterin-4-alpha-carbinolamine dehydratase
AYJ57_09130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ57_09135	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AYJ57_09140	COG2853	Lipoprotein
AYJ57_09160	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AYJ57_09165	COG0069	glutamate synthase activity
AYJ57_09170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AYJ57_09175	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AYJ57_09210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AYJ57_09250	COG0250	Participates in transcription elongation, termination and antitermination
AYJ57_09255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AYJ57_09260	COG0081	regulation of translation
AYJ57_09265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AYJ57_09270	COG0222	ribosome binding
AYJ57_09275	COG0085	RNA polymerase activity
AYJ57_09280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AYJ57_09295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AYJ57_09300	COG0049	tRNA binding
AYJ57_09305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AYJ57_09310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ57_09315	COG0051	transcription antitermination factor activity, RNA binding
AYJ57_09320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AYJ57_09325	COG0088	Forms part of the polypeptide exit tunnel
AYJ57_09330	COG0089	rRNA binding
AYJ57_09335	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AYJ57_09340	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AYJ57_09345	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AYJ57_09350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AYJ57_09355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AYJ57_09365	COG0255	Belongs to the universal ribosomal protein uL29 family
AYJ57_09370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AYJ57_09375	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AYJ57_09380	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AYJ57_09385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AYJ57_09390	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AYJ57_09395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AYJ57_09400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AYJ57_09405	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AYJ57_09410	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AYJ57_09415	COG1841	ribosomal large subunit assembly
AYJ57_09420	COG0200	Binds to the 23S rRNA
AYJ57_09425	COG0201	protein transport
AYJ57_09440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AYJ57_09445	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AYJ57_09450	COG0202	RNA polymerase activity
AYJ57_09465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYJ57_09490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYJ57_09490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYJ57_09495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_09500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYJ57_09505	COG2169	Transcriptional regulator
AYJ57_09505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYJ57_09510	COG2885	chlorophyll binding
AYJ57_09520	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYJ57_09530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYJ57_09535	COG1137	ATPase activity
AYJ57_09540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYJ57_09545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYJ57_09570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYJ57_09575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYJ57_09585	COG1218	3'(2'),5'-bisphosphate nucleotidase
AYJ57_09600	COG3145	DNA-N1-methyladenine dioxygenase activity
AYJ57_09605	COG0443	Heat shock 70 kDa protein
AYJ57_09610	COG0484	heat shock protein binding
AYJ57_09615	COG2003	Belongs to the UPF0758 family
AYJ57_09630	COG0653	protein targeting
AYJ57_09635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ57_09640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AYJ57_09645	COG0494	nUDIX hydrolase
AYJ57_09650	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AYJ57_09665	COG0779	Required for maturation of 30S ribosomal subunits
AYJ57_09690	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AYJ57_09695	COG0142	geranyltranstransferase activity
AYJ57_09705	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AYJ57_09710	COG0346	lactoylglutathione lyase activity
AYJ57_09715	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_09730	COG2200	EAL domain
AYJ57_09735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AYJ57_09740	COG1309	transcriptional regulator
AYJ57_09765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_09770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_09790	COG1609	Transcriptional regulator
AYJ57_09805	COG0583	DNA-binding transcription factor activity
AYJ57_09810	COG0577	efflux transmembrane transporter activity
AYJ57_09810	COG1136	(ABC) transporter
AYJ57_09830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AYJ57_09850	COG1522	sequence-specific DNA binding
AYJ57_09855	COG0492	ferredoxin-NADP+ reductase activity
AYJ57_09865	COG0529	Catalyzes the synthesis of activated sulfate
AYJ57_09865	COG2046	Belongs to the sulfate adenylyltransferase family
AYJ57_09875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AYJ57_09900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ57_09910	COG1435	thymidine kinase activity
AYJ57_09925	COG3273	potassium ion transport
AYJ57_09925	COG0471	metal ion transport
AYJ57_09935	COG0842	Transport permease protein
AYJ57_09940	COG1183	phosphatidylcholine synthase activity
AYJ57_09945	COG2808	Putative FMN-binding domain
AYJ57_09950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AYJ57_09955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AYJ57_09975	COG2244	polysaccharide biosynthetic process
AYJ57_10020	COG0438	transferase activity, transferring glycosyl groups
AYJ57_10040	COG1960	acyl-CoA dehydrogenase activity
AYJ57_10055	COG1022	Amp-dependent synthetase and ligase
AYJ57_10055	COG3320	Male sterility
AYJ57_10060	COG1024	Enoyl-CoA hydratase
AYJ57_10105	COG1335	isochorismatase
AYJ57_10110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ57_10115	COG0154	amidase activity
AYJ57_10120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_10125	COG2186	Transcriptional regulator
AYJ57_10140	COG0154	amidase activity
AYJ57_10145	COG0778	Nitroreductase
AYJ57_10150	COG0072	phenylalanine-tRNA ligase activity
AYJ57_10150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ57_10160	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYJ57_10180	COG0400	carboxylic ester hydrolase activity
AYJ57_10195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_10215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYJ57_10225	COG1278	Cold shock
AYJ57_10235	COG0488	(ABC) transporter
AYJ57_10240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AYJ57_10255	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AYJ57_10275	COG2894	cell division
AYJ57_10285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYJ57_10310	COG1832	CoA-binding protein
AYJ57_10315	COG0140	phosphoribosyl-ATP diphosphatase activity
AYJ57_10320	COG0107	imidazoleglycerol-phosphate synthase activity
AYJ57_10325	COG0737	Belongs to the 5'-nucleotidase family
AYJ57_10330	COG1309	transcriptional regulator
AYJ57_10350	COG1393	Belongs to the ArsC family
AYJ57_10355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AYJ57_10355	COG0116	Belongs to the methyltransferase superfamily
AYJ57_10360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AYJ57_10365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYJ57_10370	COG0131	Imidazoleglycerol-phosphate dehydratase
AYJ57_10395	COG0210	DNA helicase
AYJ57_10405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AYJ57_10425	COG0583	DNA-binding transcription factor activity
AYJ57_10430	COG1960	acyl-CoA dehydrogenase activity
AYJ57_10435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYJ57_10475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYJ57_10480	COG0527	aspartate kinase activity
AYJ57_10490	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_10505	COG1519	Transferase
AYJ57_10525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AYJ57_10525	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AYJ57_10530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AYJ57_10535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AYJ57_10580	COG0564	pseudouridine synthase activity
AYJ57_10585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYJ57_10605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYJ57_10610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_10615	COG0174	glutamine synthetase
AYJ57_10620	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ57_10620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ57_10625	COG0174	glutamine synthetase
AYJ57_10630	COG4160	amino acid transport
AYJ57_10635	COG4215	(ABC) transporter
AYJ57_10660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYJ57_10670	COG0504	CTP synthase activity
AYJ57_10695	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_10700	COG0616	signal peptide processing
AYJ57_10700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AYJ57_10715	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_10720	COG0322	excinuclease ABC activity
AYJ57_10725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYJ57_10730	COG0012	GTP binding
AYJ57_10735	COG0534	Mate efflux family protein
AYJ57_10755	COG2326	polyphosphate kinase activity
AYJ57_10765	COG0159	tryptophan synthase activity
AYJ57_10770	COG2084	Dehydrogenase
AYJ57_10775	COG3395	kinase activity
AYJ57_10780	COG0235	Class ii aldolase
AYJ57_10785	COG3622	Belongs to the hyi family
AYJ57_10790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYJ57_10800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_10810	COG0277	FAD linked oxidase domain protein
AYJ57_10825	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_10835	COG1609	Transcriptional regulator
AYJ57_10850	COG0129	dihydroxy-acid dehydratase activity
AYJ57_10855	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_10865	COG0697	spore germination
AYJ57_10870	COG2084	Dehydrogenase
AYJ57_10875	COG2721	sulfolactate sulfo-lyase activity
AYJ57_10895	COG1802	Transcriptional regulator
AYJ57_10930	COG0583	DNA-binding transcription factor activity
AYJ57_10935	COG0247	lactate metabolic process
AYJ57_10935	COG0277	FAD linked oxidase domain protein
AYJ57_10940	COG1349	DNA-binding transcription factor activity
AYJ57_10955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYJ57_10965	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_10970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_10975	COG0583	DNA-binding transcription factor activity
AYJ57_10985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_10995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_11020	COG0747	negative chemotaxis
AYJ57_11045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_11055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_11095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AYJ57_11100	COG4608	Belongs to the ABC transporter superfamily
AYJ57_11105	COG0444	Belongs to the ABC transporter superfamily
AYJ57_11110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_11115	COG0601	transmembrane transport
AYJ57_11195	COG0824	Thioesterase
AYJ57_11210	COG1960	acyl-CoA dehydrogenase activity
AYJ57_11215	COG1024	Enoyl-CoA hydratase
AYJ57_11215	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_11220	COG0183	Belongs to the thiolase family
AYJ57_11230	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ57_11240	COG1607	acyl-coa hydrolase
AYJ57_11250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_11255	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYJ57_11260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_11270	COG2721	sulfolactate sulfo-lyase activity
AYJ57_11275	COG2721	sulfolactate sulfo-lyase activity
AYJ57_11280	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_11310	COG1692	metallophosphoesterase
AYJ57_11320	COG3273	potassium ion transport
AYJ57_11320	COG0471	metal ion transport
AYJ57_11325	COG0217	transcriptional regulatory protein
AYJ57_11350	COG2267	carboxylic ester hydrolase activity
AYJ57_11360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYJ57_11370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYJ57_11370	COG0512	Glutamine amidotransferase of anthranilate synthase
AYJ57_11380	COG0670	Belongs to the BI1 family
AYJ57_11390	COG0583	DNA-binding transcription factor activity
AYJ57_11400	COG1396	sequence-specific DNA binding
AYJ57_11405	COG0483	inositol monophosphate 1-phosphatase activity
AYJ57_11425	COG0402	S-adenosylhomocysteine deaminase activity
AYJ57_11430	COG2239	Acts as a magnesium transporter
AYJ57_11435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYJ57_11440	COG0151	Belongs to the GarS family
AYJ57_11450	COG1570	exodeoxyribonuclease VII activity
AYJ57_11460	COG0741	lytic transglycosylase activity
AYJ57_11465	COG0552	protein localization to endoplasmic reticulum
AYJ57_11470	COG1285	pathogenesis
AYJ57_11475	COG2917	probably involved in intracellular septation
AYJ57_11480	COG0477	Major facilitator Superfamily
AYJ57_11490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AYJ57_11510	COG0084	hydrolase, TatD family'
AYJ57_11520	COG2001	Belongs to the MraZ family
AYJ57_11525	COG0275	rRNA processing
AYJ57_11540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYJ57_11550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AYJ57_11555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AYJ57_11565	COG2081	HI0933 family
AYJ57_11575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AYJ57_11580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYJ57_11595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AYJ57_11600	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYJ57_11605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYJ57_11610	COG0849	cell division
AYJ57_11615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYJ57_11625	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ57_11635	COG0525	valine-tRNA ligase activity
AYJ57_11650	COG0489	protein tyrosine kinase activity
AYJ57_11660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYJ57_11665	COG1686	Belongs to the peptidase S11 family
AYJ57_11760	COG2205	protein histidine kinase activity
AYJ57_11795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AYJ57_11800	COG3596	GTP binding
AYJ57_11815	COG0798	PFAM Bile acid sodium symporter
AYJ57_11820	COG0431	NADPH-dependent FMN reductase
AYJ57_11830	COG0583	DNA-binding transcription factor activity
AYJ57_11845	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_11890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYJ57_11895	COG1845	cytochrome c oxidase, subunit III
AYJ57_11900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYJ57_11905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AYJ57_11920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYJ57_11925	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AYJ57_11930	COG4221	oxidoreductase activity
AYJ57_11940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYJ57_11975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYJ57_11980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYJ57_11990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AYJ57_11995	COG0418	dihydroorotase activity
AYJ57_12025	COG0156	8-amino-7-oxononanoate synthase activity
AYJ57_12035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AYJ57_12060	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYJ57_12065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AYJ57_12070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_12075	COG0601	transmembrane transport
AYJ57_12085	COG4172	Belongs to the ABC transporter superfamily
AYJ57_12090	COG0850	regulation of cytokinetic process
AYJ57_12095	COG2894	cell division
AYJ57_12100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AYJ57_12105	COG0443	Heat shock 70 kDa protein
AYJ57_12120	COG1473	amidohydrolase
AYJ57_12130	COG0668	transmembrane transport
AYJ57_12140	COG4251	negative regulation of phosphorylation
AYJ57_12150	COG0587	DNA-directed DNA polymerase activity
AYJ57_12155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYJ57_12165	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AYJ57_12170	COG1652	LysM domain
AYJ57_12195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AYJ57_12205	COG0800	Aldolase
AYJ57_12210	COG0129	dihydroxy-acid dehydratase activity
AYJ57_12225	COG1320	monovalent cation:proton antiporter activity
AYJ57_12230	COG2212	antiporter activity
AYJ57_12245	COG1006	Multisubunit Na H antiporter MnhC subunit
AYJ57_12250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYJ57_12250	COG2111	Na H antiporter
AYJ57_12255	COG3842	ATPase activity
AYJ57_12305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AYJ57_12325	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_12330	COG4335	DNA alkylation repair
AYJ57_12340	COG0343	queuine tRNA-ribosyltransferase activity
AYJ57_12355	COG1902	pentaerythritol trinitrate reductase activity
AYJ57_12400	COG3220	belongs to the UPF0276 family
AYJ57_12415	COG0501	Belongs to the peptidase M48B family
AYJ57_12420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYJ57_12425	COG5425	PFAM Usg family protein
AYJ57_12445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYJ57_12460	COG0586	Pfam SNARE associated Golgi protein
AYJ57_12465	COG2610	gluconate transmembrane transporter activity
AYJ57_12470	COG1215	transferase activity, transferring glycosyl groups
AYJ57_12475	COG3769	mannosylglycerate metabolic process
AYJ57_12485	COG0583	DNA-binding transcription factor activity
AYJ57_12490	COG1278	Cold shock
AYJ57_12495	COG1393	Belongs to the ArsC family
AYJ57_12500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AYJ57_12550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYJ57_12565	COG1982	Orn Lys Arg decarboxylase major
AYJ57_12570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AYJ57_12570	COG1793	dna ligase
AYJ57_12600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYJ57_12610	COG1329	Transcriptional regulator
AYJ57_12615	COG1252	NADH dehydrogenase
AYJ57_12630	COG1469	GTP cyclohydrolase I activity
AYJ57_12640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ57_12645	COG0277	FAD linked oxidase domain protein
AYJ57_12655	COG1764	response to oxidative stress
AYJ57_12660	COG1846	Transcriptional regulator
AYJ57_12670	COG0006	proline dipeptidase activity
AYJ57_12705	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AYJ57_12710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYJ57_12730	COG3135	benzoate transporter
AYJ57_12750	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AYJ57_12760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYJ57_12780	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_12785	COG0308	aminopeptidase N
AYJ57_12825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYJ57_12840	COG2995	paraquat-inducible protein a
AYJ57_12845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYJ57_12845	COG3008	intermembrane lipid transfer
AYJ57_12875	COG5002	protein histidine kinase activity
AYJ57_12875	COG2176	DNA-directed DNA polymerase activity
AYJ57_12890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYJ57_12905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ57_12930	COG0784	Response regulator, receiver
AYJ57_12950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYJ57_12965	COG1160	GTP binding
AYJ57_12985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AYJ57_12990	COG3591	Belongs to the peptidase S1B family
AYJ57_13010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYJ57_13015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYJ57_13020	COG3737	Protein of unknown function (DUF498/DUF598)
AYJ57_13025	COG4133	protoheme IX ABC transporter activity
AYJ57_13030	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYJ57_13035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYJ57_13045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ57_13050	COG1268	BioY protein
AYJ57_13090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYJ57_13090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYJ57_13115	COG4176	ABC-type proline glycine betaine transport system permease component
AYJ57_13135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYJ57_13140	COG0463	Glycosyl transferase, family 2
AYJ57_13170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYJ57_13190	COG4106	trans-aconitate 2-methyltransferase activity
AYJ57_13200	COG0463	Glycosyl transferase, family 2
AYJ57_13270	COG2226	methyltransferase
AYJ57_13275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_13300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_13305	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_13315	COG0411	ABC transporter
AYJ57_13320	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYJ57_13325	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYJ57_13350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYJ57_13365	COG0248	Ppx GppA phosphatase
AYJ57_13370	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AYJ57_13455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYJ57_13460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYJ57_13465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYJ57_13470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AYJ57_13475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ57_13480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYJ57_13495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AYJ57_13505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYJ57_13510	COG3577	Aspartyl protease
AYJ57_13515	COG2095	MarC family integral membrane protein
AYJ57_13520	COG0488	(ABC) transporter
AYJ57_13525	COG0105	UTP biosynthetic process
AYJ57_13575	COG3842	ATPase activity
AYJ57_13580	COG4695	Portal protein
AYJ57_13660	COG2814	Major facilitator Superfamily
AYJ57_13665	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ57_13670	COG0022	dehydrogenase e1 component
AYJ57_13670	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ57_13675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AYJ57_13680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AYJ57_13685	COG0126	phosphoglycerate kinase activity
AYJ57_13690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYJ57_13695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYJ57_13715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYJ57_13735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AYJ57_13745	COG0316	Belongs to the HesB IscA family
AYJ57_13750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AYJ57_13760	COG0018	arginyl-trna synthetase
AYJ57_13770	COG1472	Belongs to the glycosyl hydrolase 3 family
AYJ57_13775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AYJ57_13780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AYJ57_13795	COG0717	Belongs to the dCTP deaminase family
AYJ57_13810	COG0776	regulation of translation
AYJ57_13815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYJ57_13820	COG0416	fatty acid biosynthetic process
AYJ57_13825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AYJ57_13915	COG1177	transmembrane transport
AYJ57_13920	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_13930	COG3842	ATPase activity
AYJ57_13945	COG4172	Belongs to the ABC transporter superfamily
AYJ57_13955	COG0747	negative chemotaxis
AYJ57_13965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_13985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AYJ57_13990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AYJ57_14005	COG0356	it plays a direct role in the translocation of protons across the membrane
AYJ57_14015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYJ57_14015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AYJ57_14020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AYJ57_14025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AYJ57_14040	COG0842	Transport permease protein
AYJ57_14045	COG1131	(ABC) transporter
AYJ57_14055	COG1115	amino acid carrier protein
AYJ57_14065	COG0252	asparaginase activity
AYJ57_14070	COG1027	Aspartate ammonia-lyase
AYJ57_14110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_14115	COG0583	DNA-binding transcription factor activity
AYJ57_14130	COG1064	alcohol dehydrogenase
AYJ57_14135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AYJ57_14140	COG0667	Aldo Keto reductase
AYJ57_14145	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_14155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ57_14200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYJ57_14225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ57_14230	COG1960	acyl-CoA dehydrogenase activity
AYJ57_14235	COG0009	L-threonylcarbamoyladenylate synthase
AYJ57_14240	COG1678	Uncharacterized ACR, COG1678
AYJ57_14260	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYJ57_14270	COG1573	uracil-dna glycosylase
AYJ57_14285	COG1121	(ABC) transporter
AYJ57_14290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ57_14295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ57_14300	COG1063	alcohol dehydrogenase
AYJ57_14325	COG1785	Belongs to the alkaline phosphatase family
AYJ57_14335	COG1136	(ABC) transporter
AYJ57_14345	COG4206	TonB-dependent receptor
AYJ57_14355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ57_14360	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AYJ57_14365	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AYJ57_14370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AYJ57_14390	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AYJ57_14425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AYJ57_14430	COG0181	hydroxymethylbilane synthase activity
AYJ57_14440	COG0752	glycyl-tRNA synthetase alpha subunit
AYJ57_14465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_14480	COG0730	response to heat
AYJ57_14510	COG1214	PFAM Peptidase M22, glycoprotease
AYJ57_14515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AYJ57_14530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYJ57_14540	COG1304	FMN binding
AYJ57_14550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AYJ57_14560	COG0193	aminoacyl-tRNA hydrolase activity
AYJ57_14570	COG0133	tryptophan synthase activity
AYJ57_14575	COG0442	prolyl-tRNA aminoacylation
AYJ57_14580	COG0628	permease
AYJ57_14590	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AYJ57_14600	COG3243	poly(R)-hydroxyalkanoic acid synthase
AYJ57_14610	COG0471	metal ion transport
AYJ57_14625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYJ57_14630	COG0758	DNA mediated transformation
AYJ57_14635	COG0312	modulator of DNA gyrase
AYJ57_14645	COG0109	protoheme IX farnesyltransferase activity
AYJ57_14655	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AYJ57_14665	COG3346	SURF1 family
AYJ57_14675	COG0612	Peptidase, M16
AYJ57_14700	COG4134	Bacterial extracellular solute-binding protein
AYJ57_14705	COG4135	transport system, permease component
AYJ57_14710	COG4136	ATPase activity
AYJ57_14715	COG1070	Carbohydrate kinase
AYJ57_14725	COG2816	NAD+ diphosphatase activity
AYJ57_14730	COG0737	Belongs to the 5'-nucleotidase family
AYJ57_14745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYJ57_14755	COG1116	anion transmembrane transporter activity
AYJ57_14760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_14790	COG3328	transposase activity
AYJ57_14800	COG3781	membrane
AYJ57_14805	COG0124	histidyl-tRNA synthetase
AYJ57_14815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AYJ57_14825	COG0625	glutathione transferase activity
AYJ57_14830	COG1201	RNA secondary structure unwinding
AYJ57_14845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AYJ57_14850	COG1605	Chorismate mutase
AYJ57_14850	COG0287	Prephenate dehydrogenase
AYJ57_14855	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AYJ57_14865	COG4106	trans-aconitate 2-methyltransferase activity
AYJ57_14870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYJ57_14875	COG0037	tRNA processing
AYJ57_14885	COG2885	chlorophyll binding
AYJ57_14900	COG0848	biopolymer transport protein
AYJ57_14915	COG3842	ATPase activity
AYJ57_14920	COG0395	ABC-type sugar transport system, permease component
AYJ57_14925	COG1175	transmembrane transport
AYJ57_14930	COG1653	transport
AYJ57_14945	COG2205	protein histidine kinase activity
AYJ57_14945	COG0784	Response regulator, receiver
AYJ57_14945	COG5002	protein histidine kinase activity
AYJ57_14955	COG1215	transferase activity, transferring glycosyl groups
AYJ57_14960	COG0438	transferase activity, transferring glycosyl groups
AYJ57_14965	COG0583	DNA-binding transcription factor activity
AYJ57_14990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYJ57_15010	COG1366	Belongs to the anti-sigma-factor antagonist family
AYJ57_15015	COG0183	Belongs to the thiolase family
AYJ57_15020	COG0564	pseudouridine synthase activity
AYJ57_15045	COG0776	regulation of translation
AYJ57_15055	COG0539	negative regulation of cytoplasmic translation
AYJ57_15060	COG0709	Synthesizes selenophosphate from selenide and ATP
AYJ57_15065	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AYJ57_15075	COG0069	glutamate synthase activity
AYJ57_15080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ57_15095	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_15115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_15155	COG0583	DNA-binding transcription factor activity
AYJ57_15195	COG0514	ATP-dependent DNA helicase (RecQ)
AYJ57_15200	COG1396	sequence-specific DNA binding
AYJ57_15245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AYJ57_15300	COG0745	RESPONSE REGULATOR receiver
AYJ57_15300	COG3706	GGDEF domain
AYJ57_15315	COG1595	DNA-templated transcription, initiation
AYJ57_15330	COG0583	DNA-binding transcription factor activity
AYJ57_15335	COG0596	Alpha beta hydrolase
AYJ57_15360	COG0481	GTPase activity
AYJ57_15380	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_15410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AYJ57_15415	COG0174	glutamine synthetase
AYJ57_15420	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_15430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_15455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AYJ57_15460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AYJ57_15465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYJ57_15470	COG0101	tRNA pseudouridine synthase activity
AYJ57_15475	COG3106	COG3106 Predicted ATPase
AYJ57_15485	COG3768	UPF0283 membrane protein
AYJ57_15500	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AYJ57_15515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYJ57_15520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYJ57_15530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AYJ57_15535	COG1703	isobutyryl-CoA mutase activity
AYJ57_15540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_15545	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AYJ57_15555	COG1177	transmembrane transport
AYJ57_15560	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_15575	COG0583	DNA-binding transcription factor activity
AYJ57_15580	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_15585	COG2072	flavoprotein involved in K transport
AYJ57_15590	COG1643	Atp-dependent helicase
AYJ57_15615	COG4964	Belongs to the GSP D family
AYJ57_15620	COG2885	chlorophyll binding
AYJ57_15660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AYJ57_15705	COG3415	Transposase
AYJ57_15705	COG2801	Transposase and inactivated derivatives
AYJ57_15780	COG1462	curli production assembly transport component CsgG
AYJ57_15855	COG0235	Class ii aldolase
AYJ57_15860	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AYJ57_15865	COG3920	Histidine kinase
AYJ57_15875	COG0784	Response regulator, receiver
AYJ57_15895	COG1802	Transcriptional regulator
AYJ57_15905	COG0601	transmembrane transport
AYJ57_15915	COG0444	Belongs to the ABC transporter superfamily
AYJ57_15920	COG4608	Belongs to the ABC transporter superfamily
AYJ57_15925	COG0405	Gamma-glutamyltransferase
AYJ57_15930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ57_15935	COG0577	efflux transmembrane transporter activity
AYJ57_15935	COG1136	(ABC) transporter
AYJ57_15955	COG0589	response to stress
AYJ57_15960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYJ57_15970	COG2814	Major facilitator Superfamily
AYJ57_15985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_15990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_16000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AYJ57_16005	COG4139	cobalamin transport
AYJ57_16020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYJ57_16020	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AYJ57_16025	COG1535	isochorismatase
AYJ57_16025	COG3433	isochorismatase activity
AYJ57_16030	COG1021	2,3-dihydroxybenzoate-AMP ligase
AYJ57_16035	COG0583	DNA-binding transcription factor activity
AYJ57_16040	COG2080	2 iron, 2 sulfur cluster binding
AYJ57_16045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYJ57_16060	COG0402	S-adenosylhomocysteine deaminase activity
AYJ57_16065	COG3257	ureidoglycine aminohydrolase activity
AYJ57_16070	COG1414	Transcriptional regulator
AYJ57_16100	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AYJ57_16110	COG0583	DNA-binding transcription factor activity
AYJ57_16135	COG0811	peptide transport
AYJ57_16140	COG0848	biopolymer transport protein
AYJ57_16165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_16175	COG2017	converts alpha-aldose to the beta-anomer
AYJ57_16195	COG4214	carbohydrate transport
AYJ57_16205	COG4213	ABC transporter substrate-binding protein
AYJ57_16215	COG2186	Transcriptional regulator
AYJ57_16220	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYJ57_16225	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYJ57_16230	COG1129	ABC transporter
AYJ57_16235	COG1879	ABC-type sugar transport system periplasmic component
AYJ57_16245	COG1192	Involved in chromosome partitioning
AYJ57_16255	COG4952	isomerase
AYJ57_16260	COG3347	Dehydrogenase
AYJ57_16260	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_16275	COG1129	ABC transporter
AYJ57_16280	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYJ57_16285	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYJ57_16290	COG3254	rhamnose metabolic process
AYJ57_16300	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_16320	COG1309	transcriptional regulator
AYJ57_16335	COG0513	Belongs to the DEAD box helicase family
AYJ57_16340	COG0306	phosphate transporter
AYJ57_16360	COG0583	DNA-binding transcription factor activity
AYJ57_16405	COG0517	IMP dehydrogenase activity
AYJ57_16405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYJ57_16420	COG1477	protein flavinylation
AYJ57_16430	COG1805	sodium ion transport
AYJ57_16455	COG0346	lactoylglutathione lyase activity
AYJ57_16465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AYJ57_16470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AYJ57_16475	COG2814	Major facilitator Superfamily
AYJ57_16485	COG0450	alkyl hydroperoxide reductase
AYJ57_16500	COG1519	Transferase
AYJ57_16515	COG0312	modulator of DNA gyrase
AYJ57_16525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AYJ57_16535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYJ57_16555	COG0138	bifunctional purine biosynthesis protein purh
AYJ57_16565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AYJ57_16575	COG0612	Peptidase, M16
AYJ57_16580	COG0612	Peptidase, M16
AYJ57_16585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ57_16590	COG0741	lytic transglycosylase activity
AYJ57_16610	COG1802	Transcriptional regulator
AYJ57_16620	COG0505	Belongs to the CarA family
AYJ57_16660	COG0154	amidase activity
AYJ57_16665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYJ57_16675	COG1396	sequence-specific DNA binding
AYJ57_16675	COG3800	Transcriptional regulator
AYJ57_16685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYJ57_16710	COG0439	Biotin carboxylase
AYJ57_16735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AYJ57_16755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYJ57_16760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYJ57_16765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYJ57_16775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYJ57_16775	COG0574	Belongs to the PEP-utilizing enzyme family
AYJ57_16780	COG0751	glycine-tRNA ligase activity
AYJ57_16810	COG0789	Transcriptional regulator
AYJ57_16815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYJ57_16825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AYJ57_16830	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_16835	COG3284	Transcriptional regulator
AYJ57_16840	COG0435	Glutathione S-transferase
AYJ57_16845	COG2514	catechol 2,3-dioxygenase activity
AYJ57_16850	COG0583	DNA-binding transcription factor activity
AYJ57_16855	COG0321	lipoyl(octanoyl) transferase activity
AYJ57_16875	COG0411	ABC transporter
AYJ57_16905	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AYJ57_16915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYJ57_16940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AYJ57_16950	COG0583	DNA-binding transcription factor activity
AYJ57_16965	COG2391	methyltransferase activity
AYJ57_16975	COG2814	Major facilitator Superfamily
AYJ57_16980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AYJ57_16990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AYJ57_16995	COG0667	Aldo Keto reductase
AYJ57_17025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYJ57_17035	COG1194	a g-specific adenine glycosylase
AYJ57_17050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AYJ57_17055	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AYJ57_17060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AYJ57_17065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AYJ57_17105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AYJ57_17110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AYJ57_17130	COG2321	neutral zinc metallopeptidase
AYJ57_17155	COG0395	ABC-type sugar transport system, permease component
AYJ57_17160	COG1175	transmembrane transport
AYJ57_17170	COG0410	ABC transporter
AYJ57_17185	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYJ57_17195	COG2308	Evidence 4 Homologs of previously reported genes of
AYJ57_17215	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AYJ57_17220	COG2201	protein-glutamate methylesterase activity
AYJ57_17230	COG0745	RESPONSE REGULATOR receiver
AYJ57_17235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AYJ57_17240	COG0835	chemotaxis
AYJ57_17250	COG0745	RESPONSE REGULATOR receiver
AYJ57_17260	COG0028	Belongs to the TPP enzyme family
AYJ57_17275	COG2900	Belongs to the SlyX family
AYJ57_17285	COG0587	DNA-directed DNA polymerase activity
AYJ57_17355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_17360	COG2814	Major facilitator Superfamily
AYJ57_17380	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_17390	COG3395	kinase activity
AYJ57_17395	COG4608	Belongs to the ABC transporter superfamily
AYJ57_17405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_17410	COG0601	transmembrane transport
AYJ57_17435	COG0735	belongs to the Fur family
AYJ57_17440	COG1121	(ABC) transporter
AYJ57_17445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ57_17450	COG0492	ferredoxin-NADP+ reductase activity
AYJ57_17455	COG1959	2 iron, 2 sulfur cluster binding
AYJ57_17465	COG0523	cobalamin synthesis protein
AYJ57_17490	COG2072	flavoprotein involved in K transport
AYJ57_17500	COG2144	transferase activity, transferring acyl groups
AYJ57_17525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_17530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_17535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_17545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AYJ57_17550	COG1063	alcohol dehydrogenase
AYJ57_17555	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_17560	COG4948	Mandelate Racemase Muconate Lactonizing
AYJ57_17570	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AYJ57_17590	COG1129	ABC transporter
AYJ57_17595	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYJ57_17600	COG4214	carbohydrate transport
AYJ57_17615	COG2814	Major facilitator Superfamily
AYJ57_17625	COG0583	DNA-binding transcription factor activity
AYJ57_17630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_17645	COG0601	transmembrane transport
AYJ57_17650	COG0747	negative chemotaxis
AYJ57_17665	COG0411	ABC transporter
AYJ57_17670	COG0410	ABC transporter
AYJ57_17675	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYJ57_17700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYJ57_17710	COG1129	ABC transporter
AYJ57_17730	COG1335	isochorismatase
AYJ57_17765	COG3321	synthase
AYJ57_17765	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_17765	COG0604	alcohol dehydrogenase
AYJ57_17775	COG0154	amidase activity
AYJ57_17785	COG0559	Belongs to the binding-protein-dependent transport system permease family
AYJ57_17805	COG1335	isochorismatase
AYJ57_17830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYJ57_17895	COG3284	Transcriptional regulator
AYJ57_17900	COG0601	transmembrane transport
AYJ57_17910	COG0444	Belongs to the ABC transporter superfamily
AYJ57_17915	COG4608	Belongs to the ABC transporter superfamily
AYJ57_17920	COG0747	negative chemotaxis
AYJ57_17930	COG2186	Transcriptional regulator
AYJ57_17935	COG0583	DNA-binding transcription factor activity
AYJ57_17960	COG1177	transmembrane transport
AYJ57_18005	COG0583	DNA-binding transcription factor activity
AYJ57_18010	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AYJ57_18020	COG0765	amino acid transport
AYJ57_18025	COG0765	amino acid transport
AYJ57_18030	COG1126	abc transporter atp-binding protein
AYJ57_18035	COG2855	membrane
AYJ57_18130	COG0825	malonyl-CoA metabolic process
AYJ57_18140	COG1522	sequence-specific DNA binding
AYJ57_18155	COG4067	protein conserved in archaea
AYJ57_18155	COG0189	ligase activity
AYJ57_18175	COG4948	Mandelate Racemase Muconate Lactonizing
AYJ57_18205	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_18210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYJ57_18220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYJ57_18235	COG0601	transmembrane transport
AYJ57_18240	COG0747	negative chemotaxis
AYJ57_18245	COG0583	DNA-binding transcription factor activity
AYJ57_18250	COG0697	spore germination
AYJ57_18270	COG4451	ribulose bisphosphate carboxylase, small
AYJ57_18275	COG1850	ribulose-bisphosphate carboxylase activity
AYJ57_18300	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AYJ57_18325	COG2144	transferase activity, transferring acyl groups
AYJ57_18350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_18360	COG0583	DNA-binding transcription factor activity
AYJ57_18365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AYJ57_18375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYJ57_18435	COG2197	response regulator
AYJ57_18440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYJ57_18455	COG1215	transferase activity, transferring glycosyl groups
AYJ57_18460	COG1216	Glycosyl transferase, family 2
AYJ57_18465	COG0438	transferase activity, transferring glycosyl groups
AYJ57_18470	COG2186	Transcriptional regulator
AYJ57_18495	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_18500	COG1063	alcohol dehydrogenase
AYJ57_18510	COG1695	Transcriptional regulator
AYJ57_18520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYJ57_18540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_18555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_18565	COG4948	Mandelate Racemase Muconate Lactonizing
AYJ57_18570	COG3618	amidohydrolase
AYJ57_18580	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AYJ57_18600	COG0395	ABC-type sugar transport system, permease component
AYJ57_18605	COG1175	transmembrane transport
AYJ57_18625	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AYJ57_18630	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_18635	COG0702	epimerase
AYJ57_18685	COG3453	Protein conserved in bacteria
AYJ57_18685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ57_18720	COG3750	Belongs to the UPF0335 family
AYJ57_18730	COG0235	Class ii aldolase
AYJ57_18735	COG0747	negative chemotaxis
AYJ57_18750	COG4172	Belongs to the ABC transporter superfamily
AYJ57_18760	COG0154	amidase activity
AYJ57_18775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_18780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AYJ57_18795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ57_18805	COG1902	pentaerythritol trinitrate reductase activity
AYJ57_18805	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ57_18815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYJ57_18820	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_18825	COG1522	sequence-specific DNA binding
AYJ57_18830	COG0006	proline dipeptidase activity
AYJ57_18860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_18870	COG4303	Ethanolamine ammonia lyase large subunit
AYJ57_18885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_18890	COG4172	Belongs to the ABC transporter superfamily
AYJ57_18900	COG0601	transmembrane transport
AYJ57_18915	COG1349	DNA-binding transcription factor activity
AYJ57_18960	COG0745	RESPONSE REGULATOR receiver
AYJ57_18975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ57_18985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYJ57_18990	COG2218	PFAM glutamate synthase alpha subunit domain protein
AYJ57_18995	COG0069	glutamate synthase activity
AYJ57_19010	COG2814	Major facilitator Superfamily
AYJ57_19015	COG1283	sodium-dependent phosphate transmembrane transporter activity
AYJ57_19030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ57_19045	COG0515	serine threonine protein kinase
AYJ57_19045	COG2815	serine threonine protein kinase
AYJ57_19050	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AYJ57_19070	COG0402	S-adenosylhomocysteine deaminase activity
AYJ57_19090	COG1116	anion transmembrane transporter activity
AYJ57_19110	COG1802	Transcriptional regulator
AYJ57_19130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_19135	COG2080	2 iron, 2 sulfur cluster binding
AYJ57_19140	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AYJ57_19145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYJ57_19165	COG3842	ATPase activity
AYJ57_19170	COG0395	ABC-type sugar transport system, permease component
AYJ57_19175	COG1175	transmembrane transport
AYJ57_19205	COG1489	DNA binding
AYJ57_19210	COG0668	transmembrane transport
AYJ57_19215	COG0024	Methionine aminopeptidase
AYJ57_19220	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_19225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_19230	COG2267	carboxylic ester hydrolase activity
AYJ57_19240	COG0583	DNA-binding transcription factor activity
AYJ57_19255	COG1473	amidohydrolase
AYJ57_19260	COG0583	DNA-binding transcription factor activity
AYJ57_19270	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_19285	COG3321	synthase
AYJ57_19285	COG0604	alcohol dehydrogenase
AYJ57_19285	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_19290	COG1309	transcriptional regulator
AYJ57_19300	COG2030	dehydratase
AYJ57_19315	COG1227	inorganic diphosphatase activity
AYJ57_19325	COG0280	phosphate acetyltransferase
AYJ57_19325	COG0281	malic enzyme
AYJ57_19360	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ57_19360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_19370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AYJ57_19380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_19385	COG1464	Belongs to the NlpA lipoprotein family
AYJ57_19390	COG2011	ABC-type metal ion transport system permease component
AYJ57_19395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYJ57_19410	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_19415	COG1309	transcriptional regulator
AYJ57_19430	COG4175	Glycine betaine
AYJ57_19450	COG1127	ABC transporter
AYJ57_19455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYJ57_19460	COG1609	Transcriptional regulator
AYJ57_19470	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_19480	COG3842	ATPase activity
AYJ57_19485	COG1957	nucleoside hydrolase
AYJ57_19490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AYJ57_19495	COG1940	carbohydrate kinase activity
AYJ57_19500	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AYJ57_19505	COG2116	formate transmembrane transporter activity
AYJ57_19515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_19535	COG1733	regulation of RNA biosynthetic process
AYJ57_19545	COG5463	Belongs to the UPF0441 family
AYJ57_19550	COG0754	glutathionylspermidine amidase activity
AYJ57_19575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_19580	COG2186	Transcriptional regulator
AYJ57_19585	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AYJ57_19605	COG1780	Probably involved in ribonucleotide reductase function
AYJ57_19610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ57_19615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ57_19640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYJ57_19650	COG2226	methyltransferase
AYJ57_19660	COG0395	ABC-type sugar transport system, permease component
AYJ57_19665	COG1175	transmembrane transport
AYJ57_19670	COG3842	ATPase activity
AYJ57_19675	COG3842	ATPase activity
AYJ57_19685	COG1349	DNA-binding transcription factor activity
AYJ57_19700	COG0642	Histidine kinase
AYJ57_19735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_19745	COG1309	transcriptional regulator
AYJ57_19750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AYJ57_19765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_19800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_19805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ57_19815	COG1960	acyl-CoA dehydrogenase activity
AYJ57_19840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_19860	COG0583	DNA-binding transcription factor activity
AYJ57_19870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ57_19875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ57_19895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYJ57_19900	COG1058	Belongs to the CinA family
AYJ57_19900	COG1546	Belongs to the CinA family
AYJ57_19925	COG1309	transcriptional regulator
AYJ57_19930	COG0583	DNA-binding transcription factor activity
AYJ57_19935	COG2197	response regulator
AYJ57_19940	COG4585	Histidine kinase
AYJ57_19945	COG1879	ABC-type sugar transport system periplasmic component
AYJ57_19950	COG1129	ABC transporter
AYJ57_19955	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYJ57_19965	COG3386	PFAM SMP-30 Gluconolaconase
AYJ57_19970	COG0693	protein deglycase activity
AYJ57_20020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYJ57_20050	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AYJ57_20050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_20060	COG0673	inositol 2-dehydrogenase activity
AYJ57_20065	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_20080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_20120	COG1175	transmembrane transport
AYJ57_20125	COG2188	Transcriptional regulator
AYJ57_20135	COG0583	DNA-binding transcription factor activity
AYJ57_20165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYJ57_20185	COG3718	enzyme involved in inositol metabolism
AYJ57_20190	COG3962	Belongs to the TPP enzyme family
AYJ57_20195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_20200	COG1082	Xylose isomerase domain protein TIM barrel
AYJ57_20210	COG0673	inositol 2-dehydrogenase activity
AYJ57_20215	COG1082	Xylose isomerase domain protein TIM barrel
AYJ57_20220	COG0673	inositol 2-dehydrogenase activity
AYJ57_20225	COG0673	inositol 2-dehydrogenase activity
AYJ57_20230	COG1082	Xylose isomerase domain protein TIM barrel
AYJ57_20235	COG1129	ABC transporter
AYJ57_20255	COG1609	Transcriptional regulator
AYJ57_20260	COG2132	Multicopper oxidase
AYJ57_20315	COG3119	arylsulfatase activity
AYJ57_20320	COG1049	propionate catabolic process, 2-methylcitrate cycle
AYJ57_20380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ57_20460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYJ57_20465	COG1780	Probably involved in ribonucleotide reductase function
AYJ57_20470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ57_20495	COG3842	ATPase activity
AYJ57_20535	COG4977	sequence-specific DNA binding
AYJ57_20550	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_20570	COG0655	NAD(P)H dehydrogenase (quinone) activity
AYJ57_20580	COG1335	isochorismatase
AYJ57_20590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AYJ57_20650	COG0084	hydrolase, TatD family'
AYJ57_20660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ57_20835	COG3547	Transposase (IS116 IS110 IS902 family)
AYJ57_20850	COG3547	Transposase (IS116 IS110 IS902 family)
AYJ57_20860	COG1278	Cold shock
AYJ57_20865	COG0210	DNA helicase
AYJ57_20905	COG2801	Transposase and inactivated derivatives
AYJ57_20905	COG3415	Transposase
AYJ57_21015	COG1366	Belongs to the anti-sigma-factor antagonist family
AYJ57_21020	COG1366	Belongs to the anti-sigma-factor antagonist family
AYJ57_21025	COG0784	Response regulator, receiver
AYJ57_21040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYJ57_21055	COG3415	Transposase
AYJ57_21055	COG2801	Transposase and inactivated derivatives
AYJ57_21060	COG2814	Major facilitator Superfamily
AYJ57_21070	COG0492	ferredoxin-NADP+ reductase activity
AYJ57_21075	COG3118	belongs to the thioredoxin family
AYJ57_21095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYJ57_21100	COG3608	succinylglutamate desuccinylase aspartoacylase
AYJ57_21110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYJ57_21120	COG3119	arylsulfatase activity
AYJ57_21135	COG1116	anion transmembrane transporter activity
AYJ57_21140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_21210	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AYJ57_21215	COG1609	Transcriptional regulator
AYJ57_21220	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_21350	COG0156	8-amino-7-oxononanoate synthase activity
AYJ57_21385	COG3415	Transposase
AYJ57_21385	COG2801	Transposase and inactivated derivatives
AYJ57_21415	COG0156	8-amino-7-oxononanoate synthase activity
AYJ57_21425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYJ57_21495	COG2129	metallophosphoesterase
AYJ57_21555	COG0745	RESPONSE REGULATOR receiver
AYJ57_21585	COG0514	ATP-dependent DNA helicase (RecQ)
AYJ57_21590	COG0514	ATP-dependent DNA helicase (RecQ)
AYJ57_21595	COG4957	zinc ion binding
AYJ57_21615	COG1360	Flagellar Motor Protein
AYJ57_21620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYJ57_21620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AYJ57_21645	COG1192	Involved in chromosome partitioning
AYJ57_21695	COG2963	transposase activity
AYJ57_21720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYJ57_21735	COG0765	amino acid transport
AYJ57_21740	COG0765	amino acid transport
AYJ57_21745	COG1126	abc transporter atp-binding protein
AYJ57_21750	COG0010	Belongs to the arginase family
AYJ57_21760	COG1702	phosphate starvation-inducible protein PhoH
AYJ57_21830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYJ57_21850	COG1522	sequence-specific DNA binding
AYJ57_21865	COG0583	DNA-binding transcription factor activity
AYJ57_21870	COG0789	Transcriptional regulator
AYJ57_21905	COG0583	DNA-binding transcription factor activity
AYJ57_21925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_21925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYJ57_21940	COG0583	DNA-binding transcription factor activity
AYJ57_21950	COG0601	transmembrane transport
AYJ57_21965	COG2936	dipeptidyl-peptidase activity
AYJ57_22035	COG1360	Flagellar Motor Protein
AYJ57_22045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYJ57_22065	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AYJ57_22075	COG4786	Flagellar basal body rod
AYJ57_22080	COG4786	Flagellar basal body rod
AYJ57_22090	COG1749	Flagellar hook protein flgE
AYJ57_22110	COG1706	bacterial-type flagellum-dependent cell motility
AYJ57_22125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYJ57_22135	COG5443	negative regulation of bacterial-type flagellum assembly
AYJ57_22145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYJ57_22150	COG1338	Plays a role in the flagellum-specific transport system
AYJ57_22155	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYJ57_22165	COG1766	The M ring may be actively involved in energy transduction
AYJ57_22190	COG1132	(ABC) transporter
AYJ57_22195	COG4774	siderophore transport
AYJ57_22215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_22230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ57_22260	COG1802	Transcriptional regulator
AYJ57_22265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYJ57_22275	COG0583	DNA-binding transcription factor activity
AYJ57_22280	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_22300	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ57_22300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_22305	COG4311	Sarcosine oxidase, delta subunit
AYJ57_22310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_22315	COG4977	sequence-specific DNA binding
AYJ57_22320	COG0583	DNA-binding transcription factor activity
AYJ57_22325	COG1917	Cupin 2, conserved barrel domain protein
AYJ57_22335	COG3433	isochorismatase activity
AYJ57_22335	COG1535	isochorismatase
AYJ57_22340	COG1169	isochorismate synthase
AYJ57_22345	COG3842	ATPase activity
AYJ57_22350	COG0395	ABC-type sugar transport system, permease component
AYJ57_22375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AYJ57_22400	COG0084	hydrolase, TatD family'
AYJ57_22410	COG4993	Dehydrogenase
AYJ57_22425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_22430	COG3246	L-lysine catabolic process to acetate
AYJ57_22440	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_22445	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AYJ57_22460	COG3485	protocatechuate 3,4-dioxygenase
AYJ57_22465	COG3485	protocatechuate 3,4-dioxygenase
AYJ57_22470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYJ57_22475	COG2267	carboxylic ester hydrolase activity
AYJ57_22480	COG0583	DNA-binding transcription factor activity
AYJ57_22485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYJ57_22500	COG1672	PFAM Archaeal ATPase
AYJ57_22500	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AYJ57_22510	COG0456	acetyltransferase
AYJ57_22515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYJ57_22520	COG1917	Cupin 2, conserved barrel domain protein
AYJ57_22525	COG0527	aspartate kinase activity
AYJ57_22530	COG0019	diaminopimelate decarboxylase activity
AYJ57_22550	COG1192	Involved in chromosome partitioning
AYJ57_22565	COG1305	Transglutaminase-like
AYJ57_22585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYJ57_22655	COG1157	protein secretion by the type III secretion system
AYJ57_22660	COG1815	bacterial-type flagellum-dependent cell motility
AYJ57_22665	COG1558	bacterial-type flagellum-dependent cell motility
AYJ57_22675	COG1987	bacterial-type flagellum assembly
AYJ57_22685	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYJ57_22690	COG1684	flagellar biosynthetic protein fliR
AYJ57_22695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AYJ57_22720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYJ57_22750	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AYJ57_22755	COG1178	ABC-type Fe3 transport system permease component
AYJ57_22760	COG1840	ABC-type Fe3 transport system, periplasmic component
AYJ57_22765	COG3842	ATPase activity
AYJ57_22770	COG2351	hydroxyisourate hydrolase activity
AYJ57_22795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYJ57_22815	COG2204	response regulator
AYJ57_22825	COG2864	formate dehydrogenase
AYJ57_22830	COG0437	4 iron, 4 sulfur cluster binding
AYJ57_22835	COG0243	molybdopterin cofactor binding
AYJ57_22835	COG3383	formate dehydrogenase (NAD+) activity
AYJ57_22870	COG0489	protein tyrosine kinase activity
AYJ57_22885	COG3852	Histidine kinase
AYJ57_22890	COG3383	formate dehydrogenase (NAD+) activity
AYJ57_22900	COG0425	Belongs to the sulfur carrier protein TusA family
AYJ57_22910	COG0303	'Molybdopterin
AYJ57_22915	COG1763	Mo-molybdopterin cofactor biosynthetic process
AYJ57_22920	COG0746	molybdenum cofactor guanylyltransferase activity
AYJ57_22945	COG1063	alcohol dehydrogenase
AYJ57_22960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_22965	COG1802	Transcriptional regulator
AYJ57_22970	COG1312	Catalyzes the dehydration of D-mannonate
AYJ57_22975	COG0246	Mannitol dehydrogenase
AYJ57_22985	COG0471	metal ion transport
AYJ57_22985	COG0490	domain, Protein
AYJ57_22990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ57_22995	COG0583	DNA-binding transcription factor activity
AYJ57_23000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_23010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_23015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYJ57_23015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_23030	COG0583	DNA-binding transcription factor activity
AYJ57_23040	COG0601	transmembrane transport
AYJ57_23055	COG2936	dipeptidyl-peptidase activity
AYJ57_23085	COG4608	Belongs to the ABC transporter superfamily
AYJ57_23090	COG0444	Belongs to the ABC transporter superfamily
AYJ57_23100	COG0747	negative chemotaxis
AYJ57_23135	COG1216	Glycosyl transferase, family 2
AYJ57_23140	COG1215	transferase activity, transferring glycosyl groups
AYJ57_23155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYJ57_23165	COG2755	lipolytic protein G-D-S-L family
AYJ57_23165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AYJ57_23220	COG2273	Hydrolase Family 16
AYJ57_23245	COG1215	transferase activity, transferring glycosyl groups
AYJ57_23250	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_23265	COG0546	phosphoglycolate phosphatase activity
AYJ57_23265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AYJ57_23270	COG2855	membrane
AYJ57_23275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_23295	COG4989	oxidoreductase activity
AYJ57_23310	COG0673	inositol 2-dehydrogenase activity
AYJ57_23345	COG2226	methyltransferase
AYJ57_23360	COG0210	DNA helicase
AYJ57_23375	COG2022	thiamine diphosphate biosynthetic process
AYJ57_23390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AYJ57_23395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AYJ57_23415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_23445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_23450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_23460	COG1984	allophanate hydrolase subunit 2
AYJ57_23465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AYJ57_23470	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AYJ57_23485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ57_23490	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_23500	COG0523	cobalamin synthesis protein
AYJ57_23535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ57_23545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYJ57_23550	COG0024	Methionine aminopeptidase
AYJ57_23555	COG4608	Belongs to the ABC transporter superfamily
AYJ57_23560	COG0444	Belongs to the ABC transporter superfamily
AYJ57_23570	COG0601	transmembrane transport
AYJ57_23575	COG0747	negative chemotaxis
AYJ57_23585	COG0251	oxidation-reduction process
AYJ57_23595	COG1131	(ABC) transporter
AYJ57_23610	COG2205	protein histidine kinase activity
AYJ57_23615	COG0745	RESPONSE REGULATOR receiver
AYJ57_23625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AYJ57_23630	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AYJ57_23635	COG0535	radical SAM domain protein
AYJ57_23640	COG0535	radical SAM domain protein
AYJ57_23645	COG1192	Involved in chromosome partitioning
AYJ57_23650	COG1475	DNA binding
AYJ57_23655	COG0640	Transcriptional regulator
AYJ57_23665	COG3791	Glutathione-dependent formaldehyde-activating
AYJ57_23680	COG5002	protein histidine kinase activity
AYJ57_23715	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AYJ57_23780	COG1116	anion transmembrane transporter activity
AYJ57_23795	COG3550	peptidyl-serine autophosphorylation
AYJ57_23805	COG2814	Major facilitator Superfamily
AYJ57_23815	COG1522	sequence-specific DNA binding
AYJ57_23840	COG0765	amino acid transport
AYJ57_23845	COG0765	amino acid transport
AYJ57_23855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ57_23865	COG2129	metallophosphoesterase
AYJ57_23880	COG3048	D-serine ammonia-lyase activity
AYJ57_23885	COG0730	response to heat
AYJ57_23890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_23915	COG0747	negative chemotaxis
AYJ57_23920	COG1802	Transcriptional regulator
AYJ57_23925	COG1309	transcriptional regulator
AYJ57_23940	COG1116	anion transmembrane transporter activity
AYJ57_23955	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_23960	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_23975	COG0747	negative chemotaxis
AYJ57_23980	COG0601	transmembrane transport
AYJ57_23985	COG0444	Belongs to the ABC transporter superfamily
AYJ57_24005	COG4166	transmembrane transport
AYJ57_24010	COG4608	Belongs to the ABC transporter superfamily
AYJ57_24015	COG0444	Belongs to the ABC transporter superfamily
AYJ57_24020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_24025	COG0601	transmembrane transport
AYJ57_24050	COG0402	S-adenosylhomocysteine deaminase activity
AYJ57_24060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AYJ57_24065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_24075	COG1802	Transcriptional regulator
AYJ57_24085	COG3842	ATPase activity
AYJ57_24090	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_24105	COG0154	amidase activity
AYJ57_24130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_24145	COG0154	amidase activity
AYJ57_24150	COG0574	Belongs to the PEP-utilizing enzyme family
AYJ57_24150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYJ57_24160	COG3246	L-lysine catabolic process to acetate
AYJ57_24165	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_24220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_24230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_24240	COG2072	flavoprotein involved in K transport
AYJ57_24250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYJ57_24255	COG4214	carbohydrate transport
AYJ57_24265	COG0583	DNA-binding transcription factor activity
AYJ57_24270	COG2814	Major facilitator Superfamily
AYJ57_24310	COG4948	Mandelate Racemase Muconate Lactonizing
AYJ57_24315	COG0583	DNA-binding transcription factor activity
AYJ57_24320	COG0583	DNA-binding transcription factor activity
AYJ57_24355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ57_24360	COG4529	Protein conserved in bacteria
AYJ57_24385	COG1294	oxidase, subunit
AYJ57_24390	COG1271	oxidase subunit
AYJ57_24440	COG3104	oligopeptide transport
AYJ57_24445	COG0546	phosphoglycolate phosphatase activity
AYJ57_24445	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AYJ57_24475	COG1192	Involved in chromosome partitioning
AYJ57_24490	COG1414	Transcriptional regulator
AYJ57_24500	COG2084	Dehydrogenase
AYJ57_24515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_24520	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_24530	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_24535	COG0129	dihydroxy-acid dehydratase activity
AYJ57_24550	COG2233	PERMEase
AYJ57_24560	COG2814	Major facilitator Superfamily
AYJ57_24570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_24590	COG2186	Transcriptional regulator
AYJ57_24595	COG3395	kinase activity
AYJ57_24600	COG1454	alcohol dehydrogenase
AYJ57_24620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ57_24630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AYJ57_24650	COG1129	ABC transporter
AYJ57_24655	COG1172	Belongs to the binding-protein-dependent transport system permease family
AYJ57_24690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AYJ57_24695	COG3842	ATPase activity
AYJ57_24700	COG0363	glucosamine-6-phosphate deaminase activity
AYJ57_24710	COG1175	transmembrane transport
AYJ57_24720	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AYJ57_24720	COG1940	carbohydrate kinase activity
AYJ57_24725	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AYJ57_24750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ57_24755	COG1120	ATPase activity
AYJ57_24780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_24785	COG0454	-acetyltransferase
AYJ57_24810	COG0601	transmembrane transport
AYJ57_24825	COG1522	sequence-specific DNA binding
AYJ57_24835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_24840	COG0583	DNA-binding transcription factor activity
AYJ57_24865	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_24870	COG0473	3-isopropylmalate dehydrogenase activity
AYJ57_24880	COG0154	amidase activity
AYJ57_24890	COG0154	amidase activity
AYJ57_24900	COG0601	transmembrane transport
AYJ57_24905	COG0747	negative chemotaxis
AYJ57_24910	COG4608	Belongs to the ABC transporter superfamily
AYJ57_24915	COG0444	Belongs to the ABC transporter superfamily
AYJ57_24935	COG2826	transposase and inactivated derivatives, IS30 family
AYJ57_24980	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AYJ57_24980	COG0662	Cupin 2, conserved barrel domain protein
AYJ57_25020	COG0515	serine threonine protein kinase
AYJ57_25020	COG2815	serine threonine protein kinase
AYJ57_25050	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYJ57_25080	COG2132	Multicopper oxidase
AYJ57_25085	COG1376	ErfK ybiS ycfS ynhG family protein
AYJ57_25090	COG0583	DNA-binding transcription factor activity
AYJ57_25110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYJ57_25115	COG1733	regulation of RNA biosynthetic process
AYJ57_25175	COG4964	Belongs to the GSP D family
AYJ57_25215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AYJ57_25220	COG3842	ATPase activity
AYJ57_25225	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_25230	COG1177	transmembrane transport
AYJ57_25245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_25280	COG0175	sulfate reduction
AYJ57_25350	COG0438	transferase activity, transferring glycosyl groups
AYJ57_25390	COG1192	Involved in chromosome partitioning
AYJ57_25435	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AYJ57_25440	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria