locus-tag	class	description
YALI1_A00102g	COG0443	Heat shock 70 kDa protein
YALI1_A00309g	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YALI1_A00325g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YALI1_A01061g	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YALI1_A01122g	COG0667	Aldo Keto reductase
YALI1_A01394g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YALI1_A01602g	COG1648	precorrin-2 dehydrogenase activity
YALI1_A01602g	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YALI1_A01842g	COG0596	Alpha beta hydrolase
YALI1_A01905g	COG1902	pentaerythritol trinitrate reductase activity
YALI1_A02096g	COG0037	tRNA processing
YALI1_A02335g	COG2814	Major facilitator Superfamily
YALI1_A02461g	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YALI1_A02653g	COG0004	ammonium transporteR
YALI1_A03069g	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YALI1_A03170g	COG2226	methyltransferase
YALI1_A03356g	COG0038	chloride channel
YALI1_A03402g	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YALI1_A03757g	COG0724	RNA recognition motif
YALI1_A03964g	COG0724	RNA recognition motif
YALI1_A04178g	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YALI1_A04817g	COG1051	belongs to the nudix hydrolase family
YALI1_A05052g	COG0513	Belongs to the DEAD box helicase family
YALI1_A05335g	COG0515	serine threonine protein kinase
YALI1_A05459g	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
YALI1_A05459g	COG0512	Glutamine amidotransferase of anthranilate synthase
YALI1_A05527g	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YALI1_A06169g	COG0328	RNA-DNA hybrid ribonuclease activity
YALI1_A06361g	COG4178	(ABC) transporter
YALI1_A06416g	COG0625	glutathione transferase activity
YALI1_A06453g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_A07014g	COG0477	Major facilitator Superfamily
YALI1_A08107g	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YALI1_A08512g	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
YALI1_A08546g	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YALI1_A08672g	COG2814	Major facilitator Superfamily
YALI1_A08781g	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YALI1_A09121g	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YALI1_A09522g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YALI1_A09553g	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
YALI1_A09741g	COG0328	RNA-DNA hybrid ribonuclease activity
YALI1_A09766g	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
YALI1_A09856g	COG0339	signal peptide processing
YALI1_A09893g	COG5285	phytanoyl-CoA dioxygenase
YALI1_A09911g	COG0285	dihydrofolate synthase activity
YALI1_A10254g	COG0302	gtp cyclohydrolase
YALI1_A10318g	COG2937	Belongs to the GPAT DAPAT family
YALI1_A10619g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_A11506g	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YALI1_A11654g	COG2814	Major facilitator Superfamily
YALI1_A12067g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_A12284g	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YALI1_A12437g	COG2175	clavaminate synthase activity
YALI1_A12756g	COG0328	RNA-DNA hybrid ribonuclease activity
YALI1_A12772g	COG0328	RNA-DNA hybrid ribonuclease activity
YALI1_A13454g	COG0367	asparagine synthase
YALI1_A14024g	COG2814	Major facilitator Superfamily
YALI1_A14287g	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
YALI1_A14736g	COG0612	Peptidase, M16
YALI1_A14783g	COG0515	serine threonine protein kinase
YALI1_A14783g	COG2815	serine threonine protein kinase
YALI1_A15073g	COG0328	RNA-DNA hybrid ribonuclease activity
YALI1_A15079g	COG0110	maltose O-acetyltransferase activity
YALI1_A15105g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_A15132g	COG0477	Major facilitator Superfamily
YALI1_A15624g	COG2814	Major facilitator Superfamily
YALI1_A15879g	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YALI1_A16642g	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YALI1_A17289g	COG1132	(ABC) transporter
YALI1_A17419g	COG1073	alpha beta
YALI1_A17450g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YALI1_A17640g	COG2814	Major facilitator Superfamily
YALI1_A18062g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_A18166g	COG1122	ATPase activity
YALI1_A18273g	COG0484	heat shock protein binding
YALI1_A19862g	COG2814	Major facilitator Superfamily
YALI1_A20089g	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
YALI1_A20176g	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YALI1_A20201g	COG0004	ammonium transporteR
YALI1_A20370g	COG0450	alkyl hydroperoxide reductase
YALI1_A20398g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_A20484g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_A20528g	COG0531	amino acid
YALI1_A20937g	COG3920	Histidine kinase
YALI1_A21000g	COG0656	L-ascorbic acid biosynthetic process
YALI1_A21120g	COG2267	carboxylic ester hydrolase activity
YALI1_A21203g	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YALI1_A21509g	COG0438	transferase activity, transferring glycosyl groups
YALI1_A21617g	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YALI1_A21797g	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YALI1_A22129g	COG1335	isochorismatase
YALI1_A22275g	COG0477	Major facilitator Superfamily
YALI1_A22454g	COG2175	clavaminate synthase activity
YALI1_A22539g	COG0443	Heat shock 70 kDa protein
YALI1_B00214g	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YALI1_B00357g	COG2814	Major facilitator Superfamily
YALI1_B00448g	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YALI1_B00578g	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
YALI1_B01136g	COG0563	adenylate kinase activity
YALI1_B01325g	COG0456	acetyltransferase
YALI1_B01428g	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YALI1_B01698g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YALI1_B01752g	COG1185	polyribonucleotide nucleotidyltransferase activity
YALI1_B02177g	COG0564	pseudouridine synthase activity
YALI1_B02194g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_B02283g	COG0477	Major facilitator Superfamily
YALI1_B02283g	COG2814	Major facilitator Superfamily
YALI1_B02345g	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YALI1_B02642g	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YALI1_B02833g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YALI1_B02833g	COG2124	cytochrome p450
YALI1_B02881g	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YALI1_B03198g	COG1448	Aminotransferase
YALI1_B03807g	COG0435	Glutathione S-transferase
YALI1_B03979g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_B04068g	COG2217	Heavy metal translocating P-type atpase
YALI1_B04138g	COG0588	phosphoglycerate mutase activity
YALI1_B04248g	COG2815	serine threonine protein kinase
YALI1_B04248g	COG0515	serine threonine protein kinase
YALI1_B04391g	COG2814	Major facilitator Superfamily
YALI1_B04747g	COG0300	oxidoreductase activity
YALI1_B05072g	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YALI1_B05295g	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YALI1_B05483g	COG1546	Belongs to the CinA family
YALI1_B05483g	COG1058	Belongs to the CinA family
YALI1_B05522g	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YALI1_B05571g	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YALI1_B05832g	COG0488	(ABC) transporter
YALI1_B06704g	COG0515	serine threonine protein kinase
YALI1_B06839g	COG0822	iron-sulfur transferase activity
YALI1_B07094g	COG2124	cytochrome p450
YALI1_B07284g	COG0670	Belongs to the BI1 family
YALI1_B07444g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_B07549g	COG1362	aminopeptidase activity
YALI1_B07652g	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YALI1_B07809g	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YALI1_B07852g	COG4702	Belongs to the UPF0303 family
YALI1_B07957g	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YALI1_B08123g	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YALI1_B08193g	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YALI1_B08321g	COG2124	cytochrome p450
YALI1_B08321g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YALI1_B08461g	COG2814	Major facilitator Superfamily
YALI1_B08493g	COG1902	pentaerythritol trinitrate reductase activity
YALI1_B09025g	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YALI1_B09090g	COG0655	NAD(P)H dehydrogenase (quinone) activity
YALI1_B09211g	COG0656	L-ascorbic acid biosynthetic process
YALI1_B09367g	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YALI1_B09708g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YALI1_B10130g	COG0135	phosphoribosylanthranilate isomerase activity
YALI1_B10231g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_B10449g	COG2350	Protein conserved in bacteria
YALI1_B10635g	COG0175	sulfate reduction
YALI1_B10813g	COG0529	Catalyzes the synthesis of activated sulfate
YALI1_B10813g	COG2046	Belongs to the sulfate adenylyltransferase family
YALI1_B11083g	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YALI1_B11200g	COG0714	Associated with various cellular activities
YALI1_B11448g	COG2814	Major facilitator Superfamily
YALI1_B11853g	COG0443	Heat shock 70 kDa protein
YALI1_B11983g	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YALI1_B12010g	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YALI1_B12195g	COG1643	Atp-dependent helicase
YALI1_B12337g	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
YALI1_B12409g	COG0387	Pfam Sodium calcium exchanger
YALI1_B12691g	COG0330	HflC and HflK could
YALI1_B12781g	COG0833	amino acid
YALI1_B12993g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_B13483g	COG2070	2-Nitropropane dioxygenase
YALI1_B13737g	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YALI1_B14150g	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YALI1_B15072g	COG1643	Atp-dependent helicase
YALI1_B15509g	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YALI1_B15852g	COG1643	Atp-dependent helicase
YALI1_B16022g	COG1132	(ABC) transporter
YALI1_B16419g	COG0443	Heat shock 70 kDa protein
YALI1_B17050g	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YALI1_B17838g	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YALI1_B18012g	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YALI1_B18292g	COG0004	ammonium transporteR
YALI1_B18311g	COG2124	cytochrome p450
YALI1_B18311g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YALI1_B18368g	COG0724	RNA recognition motif
YALI1_B18499g	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YALI1_B18572g	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
YALI1_B18741g	COG0515	serine threonine protein kinase
YALI1_B18955g	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YALI1_B19021g	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
YALI1_B19388g	COG1444	tRNA N-acetyltransferase activity
YALI1_B19576g	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YALI1_B19932g	COG0450	alkyl hydroperoxide reductase
YALI1_B20052g	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
YALI1_B20108g	COG0656	L-ascorbic acid biosynthetic process
YALI1_B20521g	COG1643	Atp-dependent helicase
YALI1_B20835g	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YALI1_B20870g	COG0515	serine threonine protein kinase
YALI1_B20870g	COG2815	serine threonine protein kinase
YALI1_B20919g	COG0596	Alpha beta hydrolase
YALI1_B21070g	COG0519	Catalyzes the synthesis of GMP from XMP
YALI1_B21070g	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YALI1_B21134g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_B21323g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_B21538g	COG0833	amino acid
YALI1_B22015g	COG0513	Belongs to the DEAD box helicase family
YALI1_B22321g	COG2814	Major facilitator Superfamily
YALI1_B22549g	COG1605	Chorismate mutase
YALI1_B22549g	COG0077	Prephenate dehydratase
YALI1_B22721g	COG2890	protein-(glutamine-N5) methyltransferase activity
YALI1_B22853g	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YALI1_B23153g	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YALI1_B23794g	COG0343	queuine tRNA-ribosyltransferase activity
YALI1_B23834g	COG1482	cell wall glycoprotein biosynthetic process
YALI1_B24214g	COG0489	protein tyrosine kinase activity
YALI1_B24218g	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YALI1_B24638g	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YALI1_B24901g	COG2271	Major facilitator Superfamily
YALI1_B25313g	COG1404	Belongs to the peptidase S8 family
YALI1_B25360g	COG0833	amino acid
YALI1_B25427g	COG0736	holo-[acyl-carrier-protein] synthase activity
YALI1_B25506g	COG2271	Major facilitator Superfamily
YALI1_B25553g	COG0833	amino acid
YALI1_B25593g	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YALI1_B25906g	COG0833	amino acid
YALI1_B26112g	COG0070	glutamate synthase
YALI1_B26112g	COG0069	glutamate synthase activity
YALI1_B26112g	COG0067	glutamate synthase
YALI1_B26153g	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YALI1_B26205g	COG0833	amino acid
YALI1_B26679g	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
YALI1_B26715g	COG0006	proline dipeptidase activity
YALI1_B26728g	COG0435	Glutathione S-transferase
YALI1_B26749g	COG3830	Belongs to the UPF0237 family
YALI1_B26749g	COG0560	Phosphoserine phosphatase
YALI1_B27564g	COG2814	Major facilitator Superfamily
YALI1_B27645g	COG2814	Major facilitator Superfamily
YALI1_B27968g	COG2175	clavaminate synthase activity
YALI1_B28017g	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YALI1_B28053g	COG0513	Belongs to the DEAD box helicase family
YALI1_B28349g	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YALI1_B28394g	COG0656	L-ascorbic acid biosynthetic process
YALI1_B28454g	COG3185	4-Hydroxyphenylpyruvate dioxygenase
YALI1_B28572g	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YALI1_B29243g	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
YALI1_B29505g	COG0513	Belongs to the DEAD box helicase family
YALI1_B29867g	COG3844	kynureninase activity
YALI1_B30024g	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YALI1_B30090g	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YALI1_C00141g	COG2271	Major facilitator Superfamily
YALI1_C00464g	COG0473	3-isopropylmalate dehydrogenase activity
YALI1_C00550g	COG0833	amino acid
YALI1_C01965g	COG0363	glucosamine-6-phosphate deaminase activity
YALI1_C02391g	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YALI1_C03246g	COG2226	methyltransferase
YALI1_C03335g	COG1643	Atp-dependent helicase
YALI1_C03550g	COG2814	Major facilitator Superfamily
YALI1_C03596g	COG1418	mRNA catabolic process
YALI1_C04093g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_C04143g	COG0625	glutathione transferase activity
YALI1_C04265g	COG0156	8-amino-7-oxononanoate synthase activity
YALI1_C04401g	COG0012	GTP binding
YALI1_C04531g	COG0516	GMP reductase activity
YALI1_C04531g	COG0517	IMP dehydrogenase activity
YALI1_C04553g	COG0071	Belongs to the small heat shock protein (HSP20) family
YALI1_C04570g	COG0071	Belongs to the small heat shock protein (HSP20) family
YALI1_C04882g	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YALI1_C04962g	COG2264	protein methyltransferase activity
YALI1_C04991g	COG0095	Lipoate-protein ligase
YALI1_C05880g	COG1914	H( )-stimulated, divalent metal cation uptake system
YALI1_C05908g	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YALI1_C06006g	COG2814	Major facilitator Superfamily
YALI1_C06191g	COG2814	Major facilitator Superfamily
YALI1_C06201g	COG0477	Major facilitator Superfamily
YALI1_C06222g	COG0477	Major facilitator Superfamily
YALI1_C06459g	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YALI1_C06626g	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YALI1_C06681g	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YALI1_C06917g	COG0513	Belongs to the DEAD box helicase family
YALI1_C06951g	COG0678	peroxiredoxin activity
YALI1_C06951g	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YALI1_C07077g	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YALI1_C07360g	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YALI1_C07495g	COG0484	heat shock protein binding
YALI1_C07562g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_C07780g	COG0123	including yeast histone deacetylase and acetoin utilization protein
YALI1_C07816g	COG0156	8-amino-7-oxononanoate synthase activity
YALI1_C08017g	COG2130	NADP-dependent
YALI1_C08218g	COG1418	mRNA catabolic process
YALI1_C08523g	COG2814	Major facilitator Superfamily
YALI1_C08548g	COG0277	FAD linked oxidase domain protein
YALI1_C08834g	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YALI1_C09033g	COG0114	fumarate hydratase activity
YALI1_C09072g	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YALI1_C09390g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YALI1_C09467g	COG0107	imidazoleglycerol-phosphate synthase activity
YALI1_C09696g	COG2119	membrane
YALI1_C09718g	COG2267	carboxylic ester hydrolase activity
YALI1_C09773g	COG4221	oxidoreductase activity
YALI1_C09851g	COG0708	Exodeoxyribonuclease III
YALI1_C10041g	COG0798	PFAM Bile acid sodium symporter
YALI1_C10232g	COG0833	amino acid
YALI1_C10492g	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YALI1_C10555g	COG0326	Molecular chaperone. Has ATPase activity
YALI1_C11271g	COG0515	serine threonine protein kinase
YALI1_C11271g	COG2815	serine threonine protein kinase
YALI1_C12024g	COG1250	3-hydroxyacyl-CoA dehydrogenase
YALI1_C12220g	COG2814	Major facilitator Superfamily
YALI1_C12619g	COG0656	L-ascorbic acid biosynthetic process
YALI1_C13355g	COG0440	acetolactate synthase activity
YALI1_C13689g	COG2271	Major facilitator Superfamily
YALI1_C13768g	COG0833	amino acid
YALI1_C13973g	COG2169	Transcriptional regulator
YALI1_C13973g	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YALI1_C14106g	COG2124	cytochrome p450
YALI1_C14106g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YALI1_C14595g	COG3158	transport of potassium into the cell
YALI1_C14787g	COG1362	aminopeptidase activity
YALI1_C15180g	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YALI1_C15186g	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YALI1_C15297g	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YALI1_C15398g	COG0515	serine threonine protein kinase
YALI1_C15945g	COG0405	Gamma-glutamyltransferase
YALI1_C16080g	COG0571	ribonuclease III activity
YALI1_C16200g	COG0456	acetyltransferase
YALI1_C16485g	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YALI1_C17031g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YALI1_C17031g	COG2124	cytochrome p450
YALI1_C17050g	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
YALI1_C17782g	COG0667	Aldo Keto reductase
YALI1_C17932g	COG0101	tRNA pseudouridine synthase activity
YALI1_C18258g	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
YALI1_C18771g	COG0656	L-ascorbic acid biosynthetic process
YALI1_C20023g	COG2828	Protein conserved in bacteria
YALI1_C20452g	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YALI1_C21171g	COG2226	methyltransferase
YALI1_C21234g	COG0557	exoribonuclease II activity
YALI1_C21487g	COG0180	Tryptophanyl-tRNA synthetase
YALI1_C21891g	COG0515	serine threonine protein kinase
YALI1_C22592g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YALI1_C22751g	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YALI1_C23601g	COG0477	Major facilitator Superfamily
YALI1_C23755g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YALI1_C23818g	COG2815	serine threonine protein kinase
YALI1_C23818g	COG0515	serine threonine protein kinase
YALI1_C23902g	COG0076	glutamate decarboxylase activity
YALI1_C23926g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YALI1_C24367g	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
YALI1_C24567g	COG0833	amino acid
YALI1_C24611g	COG2271	Major facilitator Superfamily
YALI1_C24647g	COG2271	Major facilitator Superfamily
YALI1_C25257g	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YALI1_C25307g	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YALI1_C25352g	COG2226	methyltransferase
YALI1_C25560g	COG1230	cation diffusion facilitator family transporter
YALI1_C25598g	COG0180	Tryptophanyl-tRNA synthetase
YALI1_C25758g	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YALI1_C25782g	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YALI1_C25789g	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YALI1_C26017g	COG0142	geranyltranstransferase activity
YALI1_C26036g	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YALI1_C26959g	COG0655	NAD(P)H dehydrogenase (quinone) activity
YALI1_C26975g	COG0655	NAD(P)H dehydrogenase (quinone) activity
YALI1_C27229g	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YALI1_C27563g	COG0655	NAD(P)H dehydrogenase (quinone) activity
YALI1_C27579g	COG0655	NAD(P)H dehydrogenase (quinone) activity
YALI1_C27834g	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YALI1_C28497g	COG0235	Class ii aldolase
YALI1_C28513g	COG2086	electron transfer activity
YALI1_C28621g	COG0405	Gamma-glutamyltransferase
YALI1_C29052g	COG0459	protein refolding
YALI1_C29066g	COG0625	glutathione transferase activity
YALI1_C29141g	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YALI1_C29506g	COG1017	nitric oxide dioxygenase activity
YALI1_C29506g	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YALI1_C29618g	COG0513	Belongs to the DEAD box helicase family
YALI1_C29810g	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YALI1_C29926g	COG0417	DNA replication proofreading
YALI1_C30022g	COG0515	serine threonine protein kinase
YALI1_C30022g	COG2815	serine threonine protein kinase
YALI1_C30187g	COG2255	four-way junction helicase activity
YALI1_C30255g	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YALI1_C30440g	COG0626	cystathionine gamma-synthase activity
YALI1_C30514g	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YALI1_C31830g	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YALI1_C31918g	COG0179	Fumarylacetoacetate (FAA) hydrolase
YALI1_C32034g	COG0596	Alpha beta hydrolase
YALI1_C32223g	COG1331	Highly conserved protein containing a thioredoxin domain
YALI1_C32517g	COG0842	Transport permease protein
YALI1_C32517g	COG1716	ATPase activity
YALI1_C32517g	COG1131	(ABC) transporter
YALI1_C32771g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_C33071g	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YALI1_C33270g	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YALI1_C33314g	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YALI1_C33353g	COG3064	Membrane
YALI1_C33353g	COG0515	serine threonine protein kinase
YALI1_C33353g	COG4991	sh3 domain protein
YALI1_C353g	COG0656	L-ascorbic acid biosynthetic process
YALI1_D00094g	COG2814	Major facilitator Superfamily
YALI1_D00173g	COG0183	Belongs to the thiolase family
YALI1_D00376g	COG2814	Major facilitator Superfamily
YALI1_D00515g	COG0531	amino acid
YALI1_D00614g	COG0626	cystathionine gamma-synthase activity
YALI1_D00703g	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YALI1_D01188g	COG0527	aspartate kinase activity
YALI1_D01188g	COG0460	homoserine dehydrogenase
YALI1_D01234g	COG0477	Major facilitator Superfamily
YALI1_D01404g	COG1902	pentaerythritol trinitrate reductase activity
YALI1_D01431g	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YALI1_D01967g	COG0585	pseudouridine synthase activity
YALI1_D02206g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_D02221g	COG0484	heat shock protein binding
YALI1_D02362g	COG0515	serine threonine protein kinase
YALI1_D02362g	COG2815	serine threonine protein kinase
YALI1_D02416g	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YALI1_D02444g	COG0604	alcohol dehydrogenase
YALI1_D02781g	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
YALI1_D03047g	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YALI1_D03167g	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YALI1_D03647g	COG0681	Belongs to the peptidase S26 family
YALI1_D03756g	COG0484	heat shock protein binding
YALI1_D03952g	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YALI1_D04186g	COG0617	tRNA 3'-terminal CCA addition
YALI1_D04261g	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YALI1_D04261g	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YALI1_D04370g	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YALI1_D04467g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_D04566g	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YALI1_D04680g	COG0085	RNA polymerase activity
YALI1_D05111g	COG0656	L-ascorbic acid biosynthetic process
YALI1_D05222g	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YALI1_D05320g	COG4178	(ABC) transporter
YALI1_D05343g	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
YALI1_D05398g	COG2815	serine threonine protein kinase
YALI1_D05398g	COG0515	serine threonine protein kinase
YALI1_D05817g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YALI1_D06311g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YALI1_D06380g	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YALI1_D06380g	COG0543	2 iron, 2 sulfur cluster binding
YALI1_D06700g	COG0024	Methionine aminopeptidase
YALI1_D06883g	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YALI1_D07089g	COG1034	ATP synthesis coupled electron transport
YALI1_D07149g	COG2226	methyltransferase
YALI1_D07232g	COG1953	Uracil, thiamine, allantoin
YALI1_D07348g	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YALI1_D08125g	COG0436	Aminotransferase
YALI1_D08715g	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YALI1_D08884g	COG3961	Belongs to the TPP enzyme family
YALI1_D08946g	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YALI1_D09356g	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YALI1_D09420g	COG0505	Belongs to the CarA family
YALI1_D09870g	COG0656	L-ascorbic acid biosynthetic process
YALI1_D10129g	COG0724	RNA recognition motif
YALI1_D10197g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_D10458g	COG0443	Heat shock 70 kDa protein
YALI1_D10812g	COG0596	Alpha beta hydrolase
YALI1_D10865g	COG0049	tRNA binding
YALI1_D10930g	COG1183	phosphatidylcholine synthase activity
YALI1_D11343g	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YALI1_D11614g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_D11686g	COG0588	phosphoglycerate mutase activity
YALI1_D11722g	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YALI1_D11769g	COG3474	cytochrome
YALI1_D11810g	COG0833	amino acid
YALI1_D12050g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_D12056g	COG0513	Belongs to the DEAD box helicase family
YALI1_D12252g	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YALI1_D12493g	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YALI1_D12626g	COG1643	Atp-dependent helicase
YALI1_D12832g	COG3961	Belongs to the TPP enzyme family
YALI1_D13238g	COG0473	3-isopropylmalate dehydrogenase activity
YALI1_D13788g	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YALI1_D13963g	COG0512	Glutamine amidotransferase of anthranilate synthase
YALI1_D14058g	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YALI1_D14260g	COG1053	succinate dehydrogenase
YALI1_D14300g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_D14489g	COG2313	pseudouridylate synthase activity
YALI1_D14532g	COG0460	homoserine dehydrogenase
YALI1_D14532g	COG0527	aspartate kinase activity
YALI1_D14609g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_D15744g	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YALI1_D15952g	COG0081	regulation of translation
YALI1_D15963g	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YALI1_D16144g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_D17355g	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
YALI1_D17482g	COG0259	pyridoxamine-phosphate oxidase activity
YALI1_D17620g	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
YALI1_D17710g	COG0745	RESPONSE REGULATOR receiver
YALI1_D17770g	COG0515	serine threonine protein kinase
YALI1_D17770g	COG2815	serine threonine protein kinase
YALI1_D17930g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_D18130g	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YALI1_D18408g	COG1069	ribulokinase activity
YALI1_D18577g	COG0215	cysteine-tRNA ligase activity
YALI1_D18845g	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YALI1_D18890g	COG0833	amino acid
YALI1_D19110g	COG0442	prolyl-tRNA aminoacylation
YALI1_D19134g	COG0612	Peptidase, M16
YALI1_D19252g	COG1960	acyl-CoA dehydrogenase activity
YALI1_D19321g	COG0354	folic acid binding
YALI1_D20050g	COG1902	pentaerythritol trinitrate reductase activity
YALI1_D20118g	COG0481	GTPase activity
YALI1_D20222g	COG0205	6-phosphofructokinase activity
YALI1_D20359g	COG0588	phosphoglycerate mutase activity
YALI1_D20473g	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YALI1_D20676g	COG0039	L-malate dehydrogenase activity
YALI1_D20706g	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
YALI1_D20768g	COG3064	Membrane
YALI1_D20768g	COG4991	sh3 domain protein
YALI1_D20768g	COG0515	serine threonine protein kinase
YALI1_D21167g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_D21458g	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YALI1_D21543g	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YALI1_D21565g	COG0037	tRNA processing
YALI1_D21586g	COG2175	clavaminate synthase activity
YALI1_D21631g	COG0531	amino acid
YALI1_D22124g	COG1022	Amp-dependent synthetase and ligase
YALI1_D22237g	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YALI1_D22247g	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YALI1_D22768g	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YALI1_D23885g	COG2814	Major facilitator Superfamily
YALI1_D23995g	COG0167	dihydroorotate dehydrogenase activity
YALI1_D24054g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_D24249g	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YALI1_D24745g	COG2815	serine threonine protein kinase
YALI1_D24745g	COG0515	serine threonine protein kinase
YALI1_D24892g	COG3104	oligopeptide transport
YALI1_D25400g	COG2814	Major facilitator Superfamily
YALI1_D26529g	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YALI1_D26956g	COG0546	phosphoglycolate phosphatase activity
YALI1_D27884g	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YALI1_D27912g	COG0154	amidase activity
YALI1_D28087g	COG0017	Asparaginyl-tRNA synthetase
YALI1_D28273g	COG0443	Heat shock 70 kDa protein
YALI1_D28569g	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YALI1_D29279g	COG2815	serine threonine protein kinase
YALI1_D29279g	COG0515	serine threonine protein kinase
YALI1_D29335g	COG0488	(ABC) transporter
YALI1_D29419g	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YALI1_D29523g	COG2814	Major facilitator Superfamily
YALI1_D29831g	COG0513	Belongs to the DEAD box helicase family
YALI1_D31186g	COG0187	DNA topoisomerase II activity
YALI1_D31624g	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YALI1_D32209g	COG0138	bifunctional purine biosynthesis protein purh
YALI1_D32424g	COG0513	Belongs to the DEAD box helicase family
YALI1_D32568g	COG2814	Major facilitator Superfamily
YALI1_D33380g	COG2873	o-acetylhomoserine
YALI1_D33418g	COG0515	serine threonine protein kinase
YALI1_D33418g	COG2815	serine threonine protein kinase
YALI1_D33465g	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YALI1_D33504g	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YALI1_D33653g	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
YALI1_D34149g	COG1131	(ABC) transporter
YALI1_D34149g	COG1716	ATPase activity
YALI1_D34149g	COG0842	Transport permease protein
YALI1_D34353g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_D34865g	COG0165	Argininosuccinate lyase
YALI1_D35258g	COG0534	Mate efflux family protein
YALI1_D35635g	COG2217	Heavy metal translocating P-type atpase
YALI1_D35735g	COG0492	ferredoxin-NADP+ reductase activity
YALI1_D36100g	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YALI1_D36215g	COG0179	Fumarylacetoacetate (FAA) hydrolase
YALI1_D36255g	COG0443	Heat shock 70 kDa protein
YALI1_E00115g	COG0443	Heat shock 70 kDa protein
YALI1_E00318g	COG0200	Binds to the 23S rRNA
YALI1_E00533g	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YALI1_E00574g	COG0509	glycine decarboxylation via glycine cleavage system
YALI1_E00588g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_E00760g	COG0529	Catalyzes the synthesis of activated sulfate
YALI1_E00948g	COG0271	Belongs to the BolA IbaG family
YALI1_E01033g	COG2264	protein methyltransferase activity
YALI1_E01159g	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YALI1_E01235g	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YALI1_E01286g	COG1132	(ABC) transporter
YALI1_E01589g	COG2759	Belongs to the formate--tetrahydrofolate ligase family
YALI1_E01793g	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YALI1_E02290g	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
YALI1_E02317g	COG0513	Belongs to the DEAD box helicase family
YALI1_E02616g	COG0033	Phosphoglucomutase
YALI1_E02832g	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YALI1_E02885g	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YALI1_E02885g	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YALI1_E02906g	COG0386	Belongs to the glutathione peroxidase family
YALI1_E02966g	COG0489	protein tyrosine kinase activity
YALI1_E03584g	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YALI1_E03762g	COG4284	Utp--glucose-1-phosphate uridylyltransferase
YALI1_E03870g	COG0277	FAD linked oxidase domain protein
YALI1_E04091g	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YALI1_E04091g	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YALI1_E04359g	COG0557	exoribonuclease II activity
YALI1_E04420g	COG0488	(ABC) transporter
YALI1_E04968g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YALI1_E05103g	COG0352	thiamine-phosphate diphosphorylase activity
YALI1_E05103g	COG0351	phosphomethylpyrimidine kinase
YALI1_E05119g	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YALI1_E05833g	COG0017	Asparaginyl-tRNA synthetase
YALI1_E05907g	COG0017	Asparaginyl-tRNA synthetase
YALI1_E05929g	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YALI1_E06178g	COG5277	cytoskeleton organization
YALI1_E06355g	COG0500	methyltransferase
YALI1_E06616g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_E07153g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_E07178g	COG1132	(ABC) transporter
YALI1_E07302g	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YALI1_E07601g	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YALI1_E08021g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_E08114g	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
YALI1_E08114g	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YALI1_E08334g	COG0445	tRNA wobble uridine modification
YALI1_E08351g	COG0436	Aminotransferase
YALI1_E08382g	COG0157	Belongs to the NadC ModD family
YALI1_E08709g	COG0028	Belongs to the TPP enzyme family
YALI1_E08782g	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YALI1_E09568g	COG2233	PERMEase
YALI1_E09750g	COG5265	(ABC) transporter
YALI1_E11370g	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YALI1_E11630g	COG0009	L-threonylcarbamoyladenylate synthase
YALI1_E11674g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YALI1_E11768g	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YALI1_E12067g	COG0228	four-way junction DNA binding
YALI1_E12206g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_E12244g	COG0085	RNA polymerase activity
YALI1_E12643g	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
YALI1_E12893g	COG0833	amino acid
YALI1_E12952g	COG0484	heat shock protein binding
YALI1_E13472g	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YALI1_E13611g	COG0328	RNA-DNA hybrid ribonuclease activity
YALI1_E13637g	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YALI1_E13677g	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YALI1_E13899g	COG0183	Belongs to the thiolase family
YALI1_E14118g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_E14153g	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YALI1_E14153g	COG1648	precorrin-2 dehydrogenase activity
YALI1_E14164g	COG2072	flavoprotein involved in K transport
YALI1_E14274g	COG3158	transport of potassium into the cell
YALI1_E14584g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YALI1_E14619g	COG0154	amidase activity
YALI1_E14644g	COG0417	DNA replication proofreading
YALI1_E14762g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_E15398g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_E15452g	COG1063	alcohol dehydrogenase
YALI1_E15469g	COG0523	cobalamin synthesis protein
YALI1_E15492g	COG1741	Belongs to the pirin family
YALI1_E15555g	COG1960	acyl-CoA dehydrogenase activity
YALI1_E15559g	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YALI1_E15659g	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YALI1_E15835g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_E15865g	COG2116	formate transmembrane transporter activity
YALI1_E16002g	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
YALI1_E16068g	COG0124	histidyl-tRNA synthetase
YALI1_E16202g	COG0443	Heat shock 70 kDa protein
YALI1_E16255g	COG0488	(ABC) transporter
YALI1_E16433g	COG0006	proline dipeptidase activity
YALI1_E16451g	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YALI1_E16493g	COG0484	heat shock protein binding
YALI1_E17214g	COG0039	L-malate dehydrogenase activity
YALI1_E17389g	COG0655	NAD(P)H dehydrogenase (quinone) activity
YALI1_E17431g	COG4589	Belongs to the CDS family
YALI1_E17466g	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YALI1_E17508g	COG2124	cytochrome p450
YALI1_E17574g	COG0423	glycine-tRNA ligase activity
YALI1_E17811g	COG0084	hydrolase, TatD family'
YALI1_E17935g	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YALI1_E18121g	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
YALI1_E18480g	COG1012	belongs to the aldehyde dehydrogenase family
YALI1_E18720g	COG0784	Response regulator, receiver
YALI1_E18720g	COG5002	protein histidine kinase activity
YALI1_E18720g	COG2198	Histidine kinase
YALI1_E18749g	COG1111	helicase
YALI1_E18749g	COG1205	dead DEAH box helicase
YALI1_E18843g	COG1196	nuclear chromosome segregation
YALI1_E18927g	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YALI1_E19172g	COG0318	PFAM AMP-dependent synthetase and ligase
YALI1_E19371g	COG0217	transcriptional regulatory protein
YALI1_E19603g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YALI1_E19696g	COG0724	RNA recognition motif
YALI1_E19871g	COG0484	heat shock protein binding
YALI1_E20192g	COG0508	dehydrogenase complex catalyzes the overall conversion of
YALI1_E20569g	COG0484	heat shock protein binding
YALI1_E20766g	COG0156	8-amino-7-oxononanoate synthase activity
YALI1_E21230g	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YALI1_E21230g	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
YALI1_E21312g	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YALI1_E21345g	COG0018	arginyl-trna synthetase
YALI1_E21406g	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YALI1_E21478g	COG2814	Major facilitator Superfamily
YALI1_E21915g	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YALI1_E22041g	COG0656	L-ascorbic acid biosynthetic process
YALI1_E22159g	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YALI1_E22238g	COG0183	Belongs to the thiolase family
YALI1_E22303g	COG0281	malic enzyme
YALI1_E22613g	COG1946	Acyl-CoA thioesterase
YALI1_E22921g	COG0006	proline dipeptidase activity
YALI1_E22961g	COG0316	Belongs to the HesB IscA family
YALI1_E23038g	COG0484	heat shock protein binding
YALI1_E23136g	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YALI1_E23555g	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YALI1_E23736g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_E23790g	COG0596	Alpha beta hydrolase
YALI1_E23899g	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YALI1_E23961g	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YALI1_E23988g	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YALI1_E23994g	COG1472	Belongs to the glycosyl hydrolase 3 family
YALI1_E24245g	COG2814	Major facilitator Superfamily
YALI1_E24343g	COG0088	Forms part of the polypeptide exit tunnel
YALI1_E24461g	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
YALI1_E24479g	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YALI1_E24567g	COG0833	amino acid
YALI1_E24922g	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YALI1_E25290g	COG0671	phosphoesterase, PA-phosphatase related
YALI1_E25364g	COG2814	Major facilitator Superfamily
YALI1_E25585g	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YALI1_E25866g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_E26525g	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YALI1_E26525g	COG0519	Catalyzes the synthesis of GMP from XMP
YALI1_E27104g	COG0123	including yeast histone deacetylase and acetoin utilization protein
YALI1_E27144g	COG0072	phenylalanine-tRNA ligase activity
YALI1_E27196g	COG1999	signal sequence binding
YALI1_E27249g	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YALI1_E28033g	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YALI1_E28130g	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YALI1_E28300g	COG0306	phosphate transporter
YALI1_E28545g	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YALI1_E29085g	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YALI1_E29179g	COG0285	dihydrofolate synthase activity
YALI1_E29235g	COG0515	serine threonine protein kinase
YALI1_E29235g	COG2815	serine threonine protein kinase
YALI1_E29319g	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YALI1_E29512g	COG1028	Short-chain dehydrogenase reductase Sdr
YALI1_E30014g	COG1132	(ABC) transporter
YALI1_E30028g	COG0678	peroxiredoxin activity
YALI1_E30400g	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YALI1_E30462g	COG0484	heat shock protein binding
YALI1_E30815g	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YALI1_E30815g	COG2124	cytochrome p450
YALI1_E30943g	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YALI1_E31754g	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YALI1_E31891g	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YALI1_E32180g	COG0004	ammonium transporteR
YALI1_E32269g	COG0210	DNA helicase
YALI1_E32423g	COG1902	pentaerythritol trinitrate reductase activity
YALI1_E32568g	COG0515	serine threonine protein kinase
YALI1_E32568g	COG2815	serine threonine protein kinase
YALI1_E32868g	COG2233	PERMEase
YALI1_E32908g	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YALI1_E33056g	COG0542	response to heat
YALI1_E33633g	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YALI1_E34072g	COG0436	Aminotransferase
YALI1_E34269g	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YALI1_E34344g	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YALI1_E34525g	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YALI1_E35410g	COG0408	coproporphyrinogen oxidase activity
YALI1_E35546g	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YALI1_E35580g	COG1185	polyribonucleotide nucleotidyltransferase activity
YALI1_E35580g	COG0539	negative regulation of cytoplasmic translation
YALI1_E35815g	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YALI1_E35955g	COG4285	Biotin-protein ligase, N terminal
YALI1_E36365g	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YALI1_E36437g	COG0427	acetyl-CoA hydrolase
YALI1_E36477g	COG0572	uridine kinase
YALI1_E36984g	COG1253	flavin adenine dinucleotide binding
YALI1_E37026g	COG0513	Belongs to the DEAD box helicase family
YALI1_E37392g	COG3118	belongs to the thioredoxin family
YALI1_E38308g	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YALI1_E38701g	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YALI1_E39210g	COG0563	adenylate kinase activity
YALI1_E39221g	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YALI1_E39676g	COG0003	Pfam Anion-transporting ATPase
YALI1_E39934g	COG1119	ATPase activity
YALI1_E40305g	COG0131	Imidazoleglycerol-phosphate dehydratase
YALI1_E40327g	COG0515	serine threonine protein kinase
YALI1_E40327g	COG2815	serine threonine protein kinase
YALI1_E40394g	COG1073	alpha beta
YALI1_E40422g	COG2815	serine threonine protein kinase
YALI1_E40422g	COG0515	serine threonine protein kinase
YALI1_E40671g	COG0753	catalase activity
YALI1_E40754g	COG0513	Belongs to the DEAD box helicase family