locus-tag	class	description
AT01_1	COG0784	Response regulator, receiver
AT01_1	COG0835	chemotaxis
AT01_1000	COG2431	L-lysine efflux transmembrane transporter activity
AT01_1001	COG1151	hydroxylamine reductase activity
AT01_1002	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AT01_1003	COG0028	Belongs to the TPP enzyme family
AT01_1005	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AT01_1006	COG0702	epimerase
AT01_1007	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT01_1009	COG1126	abc transporter atp-binding protein
AT01_1010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_1011	COG4215	(ABC) transporter
AT01_1012	COG4160	amino acid transport
AT01_1013	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_1016	COG1177	transmembrane transport
AT01_1017	COG1176	ABC-type spermidine putrescine transport system, permease component I
AT01_1018	COG3842	ATPase activity
AT01_1019	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AT01_102	COG3144	bacterial-type flagellum assembly
AT01_1022	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AT01_1023	COG2985	domain, Protein
AT01_1023	COG0569	domain protein
AT01_1028	COG0671	phosphoesterase, PA-phosphatase related
AT01_1029	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AT01_103	COG2882	bacterial-type flagellum organization
AT01_1030	COG1349	DNA-binding transcription factor activity
AT01_1031	COG0814	amino acid
AT01_1032	COG1760	l-serine dehydratase
AT01_1033	COG1686	Belongs to the peptidase S11 family
AT01_1035	COG0626	cystathionine gamma-synthase activity
AT01_104	COG1157	protein secretion by the type III secretion system
AT01_1040	COG0625	glutathione transferase activity
AT01_1041	COG4771	TonB-dependent receptor
AT01_1042	COG1120	ATPase activity
AT01_1043	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT01_1045	COG0833	amino acid
AT01_1046	COG0583	DNA-binding transcription factor activity
AT01_1047	COG2855	membrane
AT01_1048	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AT01_1049	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AT01_1049	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AT01_1049	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AT01_1050	COG1105	Belongs to the carbohydrate kinase PfkB family
AT01_1053	COG3005	denitrification pathway
AT01_1054	COG0243	molybdopterin cofactor binding
AT01_1057	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AT01_1058	COG1312	Catalyzes the dehydration of D-mannonate
AT01_1059	COG0246	Mannitol dehydrogenase
AT01_106	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AT01_1060	COG2186	Transcriptional regulator
AT01_1062	COG0523	cobalamin synthesis protein
AT01_1063	COG0671	phosphoesterase, PA-phosphatase related
AT01_1064	COG0791	NLP P60 protein
AT01_1065	COG2200	EAL domain
AT01_1066	COG4166	transmembrane transport
AT01_1067	COG4174	ABC transporter (Permease)
AT01_1068	COG4239	(ABC) transporter, permease
AT01_1069	COG4172	Belongs to the ABC transporter superfamily
AT01_1071	COG2814	Major facilitator Superfamily
AT01_1072	COG1187	pseudouridine synthase activity
AT01_1073	COG1061	Type III restriction enzyme res subunit
AT01_1075	COG3081	Nucleoid-associated protein
AT01_1076	COG3082	Protein of unknown function (DUF1414)
AT01_1077	COG3083	sulfuric ester hydrolase activity
AT01_108	COG1677	Flagellar hook-basal body complex protein FliE
AT01_1083	COG3122	Protein conserved in bacteria
AT01_1088	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AT01_109	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AT01_1091	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AT01_1091	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AT01_1092	COG0583	DNA-binding transcription factor activity
AT01_1093	COG1648	precorrin-2 dehydrogenase activity
AT01_1093	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AT01_1095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AT01_1097	COG4865	methylaspartate mutase activity
AT01_1098	COG3799	methylaspartate ammonia-lyase activity
AT01_11	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_11	COG2205	protein histidine kinase activity
AT01_110	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AT01_1101	COG1301	dicarboxylic acid transport
AT01_1139	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AT01_1140	COG2223	nitrite transmembrane transporter activity
AT01_1141	COG2198	Histidine kinase
AT01_1141	COG0642	Histidine kinase
AT01_1142	COG2197	response regulator
AT01_1143	COG0784	Response regulator, receiver
AT01_1143	COG2205	protein histidine kinase activity
AT01_1146	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AT01_1148	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AT01_1149	COG4574	serine-type endopeptidase inhibitor activity
AT01_1155	COG0814	amino acid
AT01_1159	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_116	COG1191	sigma factor activity
AT01_1162	COG1441	menaquinone biosynthetic process
AT01_1163	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AT01_1165	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AT01_1166	COG1169	isochorismate synthase
AT01_1167	COG4575	ribosome binding
AT01_1171	COG1007	ATP synthesis coupled electron transport
AT01_1172	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT01_1173	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AT01_1174	COG0713	ATP synthesis coupled electron transport
AT01_1175	COG0839	Belongs to the complex I subunit 6 family
AT01_1176	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT01_1177	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AT01_1178	COG1034	ATP synthesis coupled electron transport
AT01_118	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AT01_1180	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AT01_1181	COG0649	NAD binding
AT01_1181	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT01_1182	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT01_1184	COG0583	DNA-binding transcription factor activity
AT01_1185	COG0436	Aminotransferase
AT01_1187	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AT01_1188	COG0490	domain, Protein
AT01_1188	COG0471	metal ion transport
AT01_1189	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AT01_1190	COG3013	Belongs to the UPF0304 family
AT01_1191	COG3092	negative regulation of chromosome organization
AT01_1193	COG0857	belongs to the CobB CobQ family
AT01_1193	COG0280	phosphate acetyltransferase
AT01_1194	COG1609	Transcriptional regulator
AT01_1195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_1197	COG3037	sugar-specific permease SgaT UlaA
AT01_1198	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AT01_1199	COG0622	Phosphoesterase
AT01_1201	COG1090	epimerase
AT01_1205	COG4160	amino acid transport
AT01_1206	COG4215	(ABC) transporter
AT01_1207	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_1208	COG0163	prenyltransferase activity
AT01_1209	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AT01_1210	COG1286	toxin biosynthetic process
AT01_1211	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AT01_1212	COG0285	dihydrofolate synthase activity
AT01_1213	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AT01_1214	COG0586	Pfam SNARE associated Golgi protein
AT01_1216	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AT01_1219	COG0697	spore germination
AT01_1220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AT01_1224	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AT01_1226	COG1794	racemase activity, acting on amino acids and derivatives
AT01_1227	COG3706	GGDEF domain
AT01_1228	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AT01_1229	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT01_1229	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AT01_123	COG0506	proline dehydrogenase activity
AT01_123	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AT01_123	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AT01_1231	COG3101	peptidyl-lysine hydroxylation
AT01_1232	COG0730	response to heat
AT01_1233	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AT01_1235	COG2890	protein-(glutamine-N5) methyltransferase activity
AT01_1236	COG2840	Smr protein MutS2
AT01_1237	COG2062	phosphohistidine phosphatase, SixA
AT01_1238	COG1250	3-hydroxyacyl-CoA dehydrogenase
AT01_1238	COG1024	Enoyl-CoA hydratase
AT01_1239	COG0183	Belongs to the thiolase family
AT01_1240	COG3691	Protein conserved in bacteria
AT01_1243	COG4235	cytochrome complex assembly
AT01_1243	COG3088	subunit of a heme lyase
AT01_1244	COG4235	cytochrome complex assembly
AT01_1244	COG3088	subunit of a heme lyase
AT01_1245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AT01_1246	COG1138	Cytochrome C-type biogenesis protein
AT01_1247	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AT01_1248	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AT01_1249	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AT01_1250	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AT01_1252	COG2116	formate transmembrane transporter activity
AT01_1253	COG2824	Alkylphosphonate utilization operon protein PhnA
AT01_1255	COG0582	viral genome integration into host DNA
AT01_1256	COG2963	transposase activity
AT01_1257	COG2801	Transposase and inactivated derivatives
AT01_1264	COG3316	Transposase and inactivated derivatives
AT01_1272	COG2963	transposase activity
AT01_1273	COG2801	Transposase and inactivated derivatives
AT01_1275	COG3121	Chaperone
AT01_1276	COG3188	usher protein
AT01_1279	COG2197	response regulator
AT01_1280	COG0784	Response regulator, receiver
AT01_1280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_1280	COG2198	Histidine kinase
AT01_1280	COG2205	protein histidine kinase activity
AT01_1285	COG1228	amidohydrolase
AT01_129	COG1113	amino acid transport
AT01_1298	COG3328	transposase activity
AT01_1299	COG0582	viral genome integration into host DNA
AT01_1305	COG3328	transposase activity
AT01_131	COG1187	pseudouridine synthase activity
AT01_134	COG2226	methyltransferase
AT01_1356	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AT01_136	COG0366	Alpha amylase catalytic
AT01_1370	COG0582	viral genome integration into host DNA
AT01_1372	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AT01_1373	COG2501	S4 domain
AT01_1374	COG0215	cysteine-tRNA ligase activity
AT01_1375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AT01_1376	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AT01_1377	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AT01_1378	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AT01_1379	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AT01_1380	COG4181	ATPase activity
AT01_1381	COG2755	lipolytic protein G-D-S-L family
AT01_1382	COG0300	oxidoreductase activity
AT01_1383	COG3118	belongs to the thioredoxin family
AT01_1384	COG0330	HflC and HflK could
AT01_1385	COG1585	Membrane protein implicated in regulation of membrane protease activity
AT01_1388	COG0789	Transcriptional regulator
AT01_1389	COG2217	Heavy metal translocating P-type atpase
AT01_139	COG2197	response regulator
AT01_1390	COG3735	TraB family
AT01_1394	COG0737	Belongs to the 5'-nucleotidase family
AT01_1395	COG2223	nitrite transmembrane transporter activity
AT01_1396	COG4651	solute:proton antiporter activity
AT01_1396	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AT01_1397	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AT01_14	COG3842	ATPase activity
AT01_140	COG0322	excinuclease ABC activity
AT01_1401	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AT01_1402	COG0297	glycogen (starch) synthase activity
AT01_1403	COG0438	transferase activity, transferring glycosyl groups
AT01_1404	COG1215	transferase activity, transferring glycosyl groups
AT01_1405	COG2244	polysaccharide biosynthetic process
AT01_1406	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AT01_1407	COG0563	adenylate kinase activity
AT01_1408	COG0326	Molecular chaperone. Has ATPase activity
AT01_1409	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AT01_141	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AT01_1411	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AT01_1412	COG2963	transposase activity
AT01_1414	COG3328	transposase activity
AT01_1419	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AT01_1420	COG2832	Protein of unknown function (DUF454)
AT01_1423	COG3264	Mechanosensitive ion channel
AT01_1423	COG1196	nuclear chromosome segregation
AT01_1424	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AT01_1425	COG1309	transcriptional regulator
AT01_1426	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT01_1427	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT01_1428	COG3457	Alanine racemase
AT01_1429	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AT01_1430	COG0254	rRNA binding
AT01_1431	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AT01_1432	COG0803	Belongs to the bacterial solute-binding protein 9 family
AT01_1433	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AT01_1438	COG3695	enzyme binding
AT01_1439	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AT01_1440	COG1946	Acyl-CoA thioesterase
AT01_1441	COG0004	ammonium transporteR
AT01_1442	COG0347	Belongs to the P(II) protein family
AT01_1443	COG1132	(ABC) transporter
AT01_1444	COG1132	(ABC) transporter
AT01_1445	COG1522	sequence-specific DNA binding
AT01_1446	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AT01_1447	COG0561	phosphatase activity
AT01_1448	COG4533	DNA binding
AT01_1449	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AT01_1450	COG0824	Thioesterase
AT01_1451	COG1555	photosystem II stabilization
AT01_1452	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AT01_1453	COG0776	regulation of translation
AT01_1454	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AT01_1455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AT01_1458	COG0544	peptidyl-prolyl cis-trans isomerase activity
AT01_1459	COG0271	Belongs to the BolA IbaG family
AT01_1460	COG3056	Lipoprotein
AT01_1461	COG2223	nitrite transmembrane transporter activity
AT01_1463	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AT01_1464	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AT01_1465	COG1845	cytochrome c oxidase, subunit III
AT01_1466	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AT01_1467	COG0109	protoheme IX farnesyltransferase activity
AT01_1468	COG2814	Major facilitator Superfamily
AT01_1469	COG1666	GTP binding
AT01_1470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AT01_1471	COG0693	protein deglycase activity
AT01_1472	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AT01_1472	COG0301	tRNA thio-modification
AT01_1474	COG0142	geranyltranstransferase activity
AT01_1475	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AT01_1476	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AT01_1477	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AT01_1479	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AT01_1480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AT01_1480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AT01_1482	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AT01_1483	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AT01_1484	COG1862	Preprotein translocase
AT01_1485	COG0343	queuine tRNA-ribosyltransferase activity
AT01_1486	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AT01_1487	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AT01_1488	COG0450	alkyl hydroperoxide reductase
AT01_1492	COG0366	Alpha amylase catalytic
AT01_1494	COG1114	Component of the transport system for branched-chain amino acids
AT01_1496	COG5002	protein histidine kinase activity
AT01_1497	COG0745	RESPONSE REGULATOR receiver
AT01_1498	COG0420	3'-5' exonuclease activity
AT01_1499	COG0419	ATPase involved in DNA repair
AT01_1500	COG1940	carbohydrate kinase activity
AT01_1501	COG2974	May be involved in recombination
AT01_1503	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AT01_1509	COG2226	methyltransferase
AT01_1512	COG3459	Glycosyltransferase 36 associated
AT01_1518	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AT01_1519	COG2195	Cleaves the N-terminal amino acid of tripeptides
AT01_152	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AT01_1520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AT01_1521	COG1181	Belongs to the D-alanine--D-alanine ligase family
AT01_1523	COG3328	transposase activity
AT01_1524	COG2991	Protein conserved in bacteria
AT01_1525	COG1477	protein flavinylation
AT01_1527	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AT01_1528	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AT01_1529	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AT01_1530	COG1805	sodium ion transport
AT01_1531	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AT01_1532	COG0121	glutamine amidotransferase
AT01_1533	COG3034	peptidoglycan biosynthetic process
AT01_1535	COG1960	acyl-CoA dehydrogenase activity
AT01_1536	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
AT01_1540	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AT01_1541	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AT01_1542	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AT01_1543	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AT01_1544	COG0235	Class ii aldolase
AT01_1545	COG0436	Aminotransferase
AT01_1547	COG2814	Major facilitator Superfamily
AT01_1548	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AT01_1550	COG1846	Transcriptional regulator
AT01_1551	COG1538	Outer membrane efflux protein
AT01_1552	COG1566	PFAM secretion protein HlyD family protein
AT01_1553	COG2814	Major facilitator Superfamily
AT01_1554	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AT01_1555	COG3118	belongs to the thioredoxin family
AT01_1557	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AT01_1557	COG1042	CoA-binding domain protein
AT01_1557	COG0045	succinate-CoA ligase (ADP-forming) activity
AT01_1558	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AT01_1559	COG5544	Lipoprotein
AT01_1565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AT01_1567	COG2011	ABC-type metal ion transport system permease component
AT01_1568	COG1464	Belongs to the NlpA lipoprotein family
AT01_1570	COG1720	tRNA m6t6A37 methyltransferase activity
AT01_1572	COG3015	lipoprotein NlpE involved in copper resistance
AT01_1574	COG4681	YaeQ
AT01_1576	COG4568	rho-dependent transcription termination
AT01_1578	COG0037	tRNA processing
AT01_1579	COG0346	lactoylglutathione lyase activity
AT01_1581	COG0825	malonyl-CoA metabolic process
AT01_1583	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AT01_1584	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AT01_1585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AT01_1588	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AT01_159	COG0625	glutathione transferase activity
AT01_1590	COG0750	zinc metalloprotease
AT01_1591	COG0575	Belongs to the CDS family
AT01_1592	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AT01_1593	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AT01_1594	COG0233	cytoplasmic translational termination
AT01_1595	COG0528	UMP kinase activity
AT01_1596	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AT01_1598	COG0024	Methionine aminopeptidase
AT01_1599	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AT01_16	COG1840	ABC-type Fe3 transport system, periplasmic component
AT01_1600	COG2171	N-acyltransferase activity
AT01_1607	COG0564	pseudouridine synthase activity
AT01_1608	COG3098	single-species biofilm formation
AT01_1610	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AT01_1610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AT01_1611	COG1611	Belongs to the LOG family
AT01_1613	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AT01_1614	COG2363	Small membrane protein
AT01_1615	COG0583	DNA-binding transcription factor activity
AT01_1617	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AT01_1618	COG2166	iron-sulfur cluster assembly
AT01_1619	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AT01_1620	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AT01_1624	COG0860	N-Acetylmuramoyl-L-alanine amidase
AT01_1625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AT01_1625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AT01_1626	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AT01_1627	COG1074	ATP-dependent DNA helicase activity
AT01_1628	COG1025	Belongs to the peptidase M16 family
AT01_1629	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AT01_1631	COG1139	Iron-sulfur cluster binding protein
AT01_1632	COG0247	lactate metabolic process
AT01_1633	COG1012	belongs to the aldehyde dehydrogenase family
AT01_1634	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AT01_1642	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AT01_1645	COG3066	DNA modification
AT01_1646	COG0861	Integral membrane protein TerC family
AT01_1647	COG0667	Aldo Keto reductase
AT01_1648	COG0477	Major facilitator Superfamily
AT01_1649	COG0204	Acyl-transferase
AT01_1649	COG0318	PFAM AMP-dependent synthetase and ligase
AT01_1650	COG1609	Transcriptional regulator
AT01_1651	COG1609	Transcriptional regulator
AT01_1652	COG0019	diaminopimelate decarboxylase activity
AT01_1653	COG0583	DNA-binding transcription factor activity
AT01_1654	COG2814	Major facilitator Superfamily
AT01_1662	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AT01_1665	COG2165	general secretion pathway protein
AT01_1672	COG0288	reversible hydration of carbon dioxide
AT01_1673	COG1733	regulation of RNA biosynthetic process
AT01_1674	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_1676	COG0484	heat shock protein binding
AT01_1677	COG1609	Transcriptional regulator
AT01_1678	COG2271	Major facilitator Superfamily
AT01_1681	COG1522	sequence-specific DNA binding
AT01_1682	COG3706	GGDEF domain
AT01_17	COG2271	Major facilitator Superfamily
AT01_1701	COG0582	viral genome integration into host DNA
AT01_1704	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AT01_1705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AT01_1706	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AT01_1707	COG4974	Belongs to the 'phage' integrase family
AT01_1708	COG0716	FMN binding
AT01_1709	COG4452	Inner membrane protein CreD
AT01_1710	COG2205	protein histidine kinase activity
AT01_1711	COG0745	RESPONSE REGULATOR receiver
AT01_1713	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AT01_1715	COG1272	protein, Hemolysin III
AT01_1716	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_1717	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AT01_1717	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AT01_1718	COG0509	glycine decarboxylation via glycine cleavage system
AT01_1719	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AT01_1720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT01_1721	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT01_1722	COG0006	proline dipeptidase activity
AT01_1724	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AT01_1725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AT01_1726	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AT01_1728	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AT01_1729	COG0583	DNA-binding transcription factor activity
AT01_173	COG3328	transposase activity
AT01_1731	COG1279	arginine transmembrane transporter activity
AT01_1734	COG0191	fructose-bisphosphate aldolase activity
AT01_1736	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AT01_1737	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AT01_1738	COG0501	Belongs to the peptidase M48B family
AT01_1740	COG1166	arginine decarboxylase activity
AT01_1741	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AT01_1744	COG0640	Transcriptional regulator
AT01_1745	COG3091	SprT-like family
AT01_1746	COG2356	endonuclease I
AT01_1747	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AT01_1748	COG0189	ligase activity
AT01_1749	COG1678	Uncharacterized ACR, COG1678
AT01_1750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AT01_1751	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AT01_1753	COG2805	Type II/IV secretion system protein
AT01_1754	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AT01_1755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AT01_1756	COG0762	integral membrane protein
AT01_1757	COG1872	DUF167
AT01_1758	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AT01_1759	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AT01_1761	COG2066	Belongs to the glutaminase family
AT01_1762	COG3171	Protein conserved in bacteria
AT01_1764	COG1194	a g-specific adenine glycosylase
AT01_1765	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AT01_1766	COG0741	lytic transglycosylase activity
AT01_1770	COG4974	Belongs to the 'phage' integrase family
AT01_1791	COG3316	Transposase and inactivated derivatives
AT01_1793	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AT01_1794	COG3316	Transposase and inactivated derivatives
AT01_1795	COG4932	domain protein
AT01_1795	COG2373	Large extracellular alpha-helical protein
AT01_1795	COG1388	LysM domain
AT01_1807	COG4773	Receptor
AT01_1808	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AT01_1809	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT01_1810	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT01_1811	COG1120	ATPase activity
AT01_1812	COG4264	IucA IucC family
AT01_1814	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AT01_1815	COG0076	glutamate decarboxylase activity
AT01_1816	COG4114	ferric iron reductase
AT01_1817	COG3316	Transposase and inactivated derivatives
AT01_1818	COG2963	transposase activity
AT01_1825	COG0583	DNA-binding transcription factor activity
AT01_1826	COG3961	Belongs to the TPP enzyme family
AT01_1827	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AT01_183	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AT01_1842	COG1157	protein secretion by the type III secretion system
AT01_1844	COG4789	Type iii secretion
AT01_1858	COG2197	response regulator
AT01_1862	COG3209	COG3209 Rhs family protein
AT01_1864	COG3209	COG3209 Rhs family protein
AT01_1866	COG3501	Rhs element vgr protein
AT01_1885	COG0477	Major facilitator Superfamily
AT01_1886	COG1609	Transcriptional regulator
AT01_1891	COG0477	Major facilitator Superfamily
AT01_1892	COG5001	Diguanylate cyclase
AT01_1894	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AT01_1895	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AT01_1896	COG0309	Hydrogenase expression formation protein (HypE)
AT01_1897	COG0409	Hydrogenase expression formation protein
AT01_1898	COG0298	carbon dioxide binding
AT01_1899	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AT01_1900	COG0375	protein maturation
AT01_1901	COG1773	rubredoxin
AT01_1902	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AT01_1903	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AT01_1904	COG5557	Pfam Polysulphide reductase, NrfD
AT01_1905	COG0437	4 iron, 4 sulfur cluster binding
AT01_1906	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AT01_1913	COG4592	Periplasmic binding protein
AT01_1914	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT01_1915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT01_1916	COG1120	ATPase activity
AT01_1918	COG4774	siderophore transport
AT01_1923	COG4964	Belongs to the GSP D family
AT01_1933	COG0848	biopolymer transport protein
AT01_1934	COG0811	peptide transport
AT01_1935	COG0626	cystathionine gamma-synthase activity
AT01_1936	COG0586	Pfam SNARE associated Golgi protein
AT01_1937	COG2207	Transcriptional regulator
AT01_1939	COG1979	alcohol dehydrogenase
AT01_1940	COG0656	L-ascorbic acid biosynthetic process
AT01_1943	COG2132	Multicopper oxidase
AT01_1944	COG0204	Acyl-transferase
AT01_1946	COG2249	NAD(P)H dehydrogenase (quinone) activity
AT01_1947	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AT01_1949	COG0187	DNA topoisomerase II activity
AT01_1950	COG3150	esterase
AT01_1951	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AT01_1952	COG3151	Protein conserved in bacteria
AT01_1953	COG0494	nUDIX hydrolase
AT01_1955	COG5463	Belongs to the UPF0441 family
AT01_1956	COG0754	glutathionylspermidine amidase activity
AT01_1957	COG3384	dioxygenase
AT01_1958	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AT01_1960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AT01_1960	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AT01_1961	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AT01_1962	COG3025	triphosphatase activity
AT01_1963	COG4991	sh3 domain protein
AT01_1964	COG0617	tRNA 3'-terminal CCA addition
AT01_1966	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AT01_1967	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AT01_1968	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AT01_1970	COG0358	DNA primase activity
AT01_1971	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AT01_1976	COG3247	response to pH
AT01_1977	COG0446	pyridine nucleotide-disulphide oxidoreductase
AT01_1977	COG1902	pentaerythritol trinitrate reductase activity
AT01_1978	COG2813	Specifically methylates the guanine in position
AT01_1980	COG1451	nucleotide metabolic process
AT01_1981	COG0673	inositol 2-dehydrogenase activity
AT01_1982	COG0861	Integral membrane protein TerC family
AT01_1983	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AT01_1985	COG2721	sulfolactate sulfo-lyase activity
AT01_1986	COG0246	Mannitol dehydrogenase
AT01_1987	COG1904	glucuronate isomerase
AT01_1988	COG2271	Major facilitator Superfamily
AT01_1991	COG0586	Pfam SNARE associated Golgi protein
AT01_1994	COG4575	ribosome binding
AT01_1995	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AT01_1997	COG2259	Doxx family
AT01_1998	COG0435	Glutathione S-transferase
AT01_1999	COG0583	DNA-binding transcription factor activity
AT01_2	COG3157	Type VI secretion system effector, Hcp
AT01_20	COG4565	transcriptional regulatory protein
AT01_2000	COG1741	Belongs to the pirin family
AT01_2001	COG0667	Aldo Keto reductase
AT01_2009	COG3328	transposase activity
AT01_201	COG0625	glutathione transferase activity
AT01_2011	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AT01_2013	COG0792	nuclease activity
AT01_2014	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AT01_2015	COG2823	Periplasmic or secreted lipoprotein
AT01_2016	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AT01_2017	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AT01_2018	COG2198	Histidine kinase
AT01_2018	COG5002	protein histidine kinase activity
AT01_2018	COG0784	Response regulator, receiver
AT01_2019	COG1242	4 iron, 4 sulfur cluster binding
AT01_2020	COG0070	glutamate synthase
AT01_2020	COG0067	glutamate synthase
AT01_2020	COG0069	glutamate synthase activity
AT01_2021	COG0493	'glutamate synthase
AT01_2023	COG2969	positive regulation of protein catabolic process
AT01_2024	COG0625	glutathione transferase activity
AT01_2025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AT01_2026	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AT01_2027	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AT01_2028	COG3105	Protein conserved in bacteria
AT01_2029	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AT01_2030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AT01_2031	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AT01_2032	COG5007	Belongs to the BolA IbaG family
AT01_2033	COG3113	response to antibiotic
AT01_2034	COG2854	intermembrane phospholipid transfer
AT01_2035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AT01_2036	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AT01_2037	COG1127	ABC transporter
AT01_2038	COG0530	calcium, potassium:sodium antiporter activity
AT01_2039	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AT01_2039	COG0517	IMP dehydrogenase activity
AT01_2040	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AT01_2041	COG3117	lipopolysaccharide transmembrane transporter activity
AT01_2042	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AT01_2043	COG1137	ATPase activity
AT01_2044	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AT01_2046	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_2048	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_2050	COG0540	Belongs to the ATCase OTCase family
AT01_2051	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AT01_2053	COG0366	Alpha amylase catalytic
AT01_2054	COG1263	PTS System
AT01_2054	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AT01_2055	COG1609	Transcriptional regulator
AT01_2056	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AT01_2057	COG3711	transcriptional antiterminator
AT01_2057	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_2062	COG3964	amidohydrolase
AT01_2068	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AT01_2069	COG3783	Cytochrome b(562)
AT01_2070	COG0312	modulator of DNA gyrase
AT01_2071	COG3028	Belongs to the UPF0307 family
AT01_2072	COG2732	(Barnase) inhibitor
AT01_2075	COG1289	transmembrane transporter activity
AT01_2076	COG1566	PFAM secretion protein HlyD family protein
AT01_2078	COG0583	DNA-binding transcription factor activity
AT01_2079	COG0312	modulator of DNA gyrase
AT01_2080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AT01_2081	COG3164	Protein of unknown function
AT01_2082	COG1530	ribonuclease E activity
AT01_2084	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AT01_2085	COG1792	Involved in formation and maintenance of cell shape
AT01_2086	COG1077	Cell shape determining protein MreB Mrl
AT01_2087	COG2200	EAL domain
AT01_2087	COG2199	diguanylate cyclase activity
AT01_2089	COG0604	alcohol dehydrogenase
AT01_209	COG2203	Gaf domain
AT01_209	COG3706	GGDEF domain
AT01_209	COG4251	negative regulation of phosphorylation
AT01_209	COG5001	Diguanylate cyclase
AT01_2091	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AT01_2093	COG0511	ligase activity, forming carbon-carbon bonds
AT01_2094	COG0439	Biotin carboxylase
AT01_2095	COG3924	membrane
AT01_2096	COG4145	pantothenate transmembrane transporter activity
AT01_2097	COG2264	protein methyltransferase activity
AT01_2098	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AT01_2099	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AT01_21	COG3290	protein histidine kinase activity
AT01_210	COG3008	intermembrane lipid transfer
AT01_2100	COG3706	GGDEF domain
AT01_2101	COG3133	Outer membrane lipoprotein
AT01_2102	COG1278	Cold shock
AT01_2103	COG1278	Cold shock
AT01_2105	COG1069	ribulokinase activity
AT01_2107	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_2108	COG1129	ABC transporter
AT01_211	COG2995	paraquat-inducible protein a
AT01_2110	COG1560	Kdo2-lipid A biosynthetic process
AT01_2113	COG1380	Effector of murein hydrolase LrgA
AT01_2114	COG0583	DNA-binding transcription factor activity
AT01_2115	COG0025	NhaP-type Na H and K H
AT01_2116	COG2252	PERMEase
AT01_2119	COG3550	peptidyl-serine autophosphorylation
AT01_212	COG1956	GAF domain-containing protein
AT01_2121	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AT01_2122	COG2315	Protein conserved in bacteria
AT01_2123	COG1448	Aminotransferase
AT01_2124	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AT01_2125	COG0305	Participates in initiation and elongation during chromosome replication
AT01_2129	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AT01_2132	COG0735	belongs to the Fur family
AT01_2133	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AT01_2134	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AT01_2135	COG2937	Belongs to the GPAT DAPAT family
AT01_2137	COG3161	chorismate lyase activity
AT01_2139	COG4580	involved in the transport of maltose and maltodextrins
AT01_214	COG0793	Belongs to the peptidase S41A family
AT01_2141	COG2182	Extracellular solute-binding protein
AT01_2142	COG1175	transmembrane transport
AT01_2143	COG3833	ABC-type maltose transport systems, permease component
AT01_2144	COG3223	Belongs to the PsiE family
AT01_2145	COG0166	Belongs to the GPI family
AT01_2147	COG0527	aspartate kinase activity
AT01_215	COG0501	Belongs to the peptidase M48B family
AT01_2150	COG1414	Transcriptional regulator
AT01_2151	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AT01_2152	COG2224	Isocitrate lyase
AT01_2153	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AT01_216	COG2814	Major facilitator Superfamily
AT01_2162	COG0138	bifunctional purine biosynthesis protein purh
AT01_2163	COG0151	Belongs to the GarS family
AT01_2166	COG3068	Protein conserved in bacteria
AT01_2167	COG1515	deoxyribonuclease V activity
AT01_2168	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AT01_2169	COG2816	NAD+ diphosphatase activity
AT01_217	COG0823	Involved in the tonB-independent uptake of proteins
AT01_2170	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AT01_2171	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AT01_2173	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AT01_2175	COG2022	thiamine diphosphate biosynthetic process
AT01_2177	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AT01_2178	COG0085	RNA polymerase activity
AT01_2179	COG0222	ribosome binding
AT01_2181	COG0081	regulation of translation
AT01_2182	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AT01_2183	COG0250	Participates in transcription elongation, termination and antitermination
AT01_2184	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AT01_2185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AT01_219	COG3023	N-Acetylmuramoyl-L-alanine amidase
AT01_2191	COG1072	(Pantothenic acid kinase))
AT01_2192	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AT01_2192	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AT01_2199	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AT01_22	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AT01_2200	COG1739	Uncharacterized protein family UPF0029
AT01_2202	COG1024	Enoyl-CoA hydratase
AT01_2202	COG1250	3-hydroxyacyl-CoA dehydrogenase
AT01_2203	COG0183	Belongs to the thiolase family
AT01_2205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AT01_2209	COG0805	protein transport
AT01_221	COG1988	membrane-bound metal-dependent
AT01_2211	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AT01_2212	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AT01_2214	COG2226	methyltransferase
AT01_2215	COG1322	Protein conserved in bacteria
AT01_2216	COG0586	Pfam SNARE associated Golgi protein
AT01_2217	COG1966	Carbon starvation protein
AT01_2219	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AT01_222	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AT01_2220	COG0412	Dienelactone hydrolase
AT01_2221	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AT01_2223	COG0583	DNA-binding transcription factor activity
AT01_2224	COG0679	Auxin Efflux Carrier
AT01_2225	COG0584	glycerophosphoryl diester phosphodiesterase
AT01_2226	COG3842	ATPase activity
AT01_2227	COG0395	ABC-type sugar transport system, permease component
AT01_2228	COG1175	transmembrane transport
AT01_2229	COG1653	transport
AT01_2236	COG0410	ABC transporter
AT01_2237	COG0411	ABC transporter
AT01_2238	COG4177	L-phenylalanine transmembrane transporter activity
AT01_2239	COG0559	Belongs to the binding-protein-dependent transport system permease family
AT01_224	COG3842	ATPase activity
AT01_2240	COG0683	leucine binding
AT01_2242	COG3328	transposase activity
AT01_2244	COG2177	Part of the ABC transporter FtsEX involved in
AT01_2245	COG2884	Cell division ATP-binding protein ftsE
AT01_2246	COG0552	protein localization to endoplasmic reticulum
AT01_2247	COG0742	ribosomal rna small subunit methyltransferase
AT01_2248	COG3776	membrane
AT01_225	COG0395	ABC-type sugar transport system, permease component
AT01_2251	COG3714	YhhN family
AT01_2253	COG0425	Belongs to the sulfur carrier protein TusA family
AT01_2254	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AT01_2256	COG0247	lactate metabolic process
AT01_2258	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AT01_2259	COG2271	Major facilitator Superfamily
AT01_226	COG1175	transmembrane transport
AT01_2260	COG0584	glycerophosphoryl diester phosphodiesterase
AT01_2261	COG0561	phosphatase activity
AT01_2262	COG2267	carboxylic ester hydrolase activity
AT01_2264	COG1280	lysine exporter protein (LysE YggA)
AT01_2266	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AT01_2267	COG2050	protein possibly involved in aromatic compounds catabolism
AT01_2269	COG0598	Magnesium transport protein CorA
AT01_2271	COG5564	TIM-barrel signal transduction protein
AT01_2272	COG5441	Belongs to the UPF0261 family
AT01_2274	COG0210	DNA helicase
AT01_2275	COG1011	Hydrolase
AT01_2276	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AT01_2277	COG3159	Protein conserved in bacteria
AT01_2278	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AT01_2279	COG5567	small periplasmic lipoprotein
AT01_228	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_2281	COG3072	Adenylate cyclase
AT01_2282	COG0181	hydroxymethylbilane synthase activity
AT01_2283	COG1587	Uroporphyrinogen-III synthase
AT01_2284	COG2959	enzyme of heme biosynthesis
AT01_2285	COG3071	HemY protein
AT01_229	COG1917	Cupin 2, conserved barrel domain protein
AT01_2290	COG1113	amino acid transport
AT01_2293	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AT01_2294	COG2244	polysaccharide biosynthetic process
AT01_2295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AT01_2296	COG0456	acetyltransferase
AT01_2297	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AT01_2298	COG1088	dTDP-glucose 4,6-dehydratase activity
AT01_2299	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AT01_23	COG3052	prosthetic group binding
AT01_230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AT01_2300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AT01_2301	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AT01_2302	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AT01_2303	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AT01_2304	COG3118	belongs to the thioredoxin family
AT01_2306	COG0248	Ppx GppA phosphatase
AT01_2309	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AT01_2311	COG3121	Chaperone
AT01_2314	COG3121	Chaperone
AT01_2315	COG4104	PAAR repeat-containing protein
AT01_2318	COG0583	DNA-binding transcription factor activity
AT01_232	COG0427	acetyl-CoA hydrolase
AT01_2320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AT01_2321	COG0129	dihydroxy-acid dehydratase activity
AT01_2322	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AT01_2323	COG3978	acetolactate synthase activity
AT01_2326	COG3085	chromosome segregation
AT01_2327	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_2328	COG0583	DNA-binding transcription factor activity
AT01_2329	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_233	COG0583	DNA-binding transcription factor activity
AT01_2330	COG1129	ABC transporter
AT01_2331	COG1879	ABC-type sugar transport system periplasmic component
AT01_2339	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AT01_234	COG1024	Enoyl-CoA hydratase
AT01_2342	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AT01_2346	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AT01_2347	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AT01_2347	COG0678	peroxiredoxin activity
AT01_2348	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AT01_235	COG1703	isobutyryl-CoA mutase activity
AT01_236	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AT01_236	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AT01_2360	COG0165	Argininosuccinate lyase
AT01_2361	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AT01_2362	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AT01_2364	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AT01_2370	COG0527	aspartate kinase activity
AT01_2370	COG0460	homoserine dehydrogenase
AT01_2371	COG0626	cystathionine gamma-synthase activity
AT01_2372	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AT01_2374	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AT01_2375	COG1609	Transcriptional regulator
AT01_2376	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AT01_2377	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AT01_2378	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AT01_2379	COG1575	Belongs to the MenA family. Type 1 subfamily
AT01_238	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AT01_2381	COG3074	FtsZ-dependent cytokinesis
AT01_2382	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AT01_2383	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AT01_2384	COG1494	fructose-1,6-bisphosphatase
AT01_2385	COG2814	Major facilitator Superfamily
AT01_2387	COG3152	Membrane
AT01_239	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AT01_2390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AT01_2392	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AT01_2393	COG3678	ATP-independent chaperone mediated protein folding
AT01_2394	COG0745	RESPONSE REGULATOR receiver
AT01_2395	COG2205	protein histidine kinase activity
AT01_2396	COG2169	Transcriptional regulator
AT01_2396	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AT01_2397	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AT01_2398	COG1045	serine acetyltransferase
AT01_2399	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AT01_24	COG2301	Belongs to the HpcH HpaI aldolase family
AT01_240	COG1121	(ABC) transporter
AT01_2400	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AT01_2401	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AT01_2402	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AT01_2403	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AT01_2404	COG4942	peptidase
AT01_2405	COG2861	carbohydrate metabolic process
AT01_2406	COG1063	alcohol dehydrogenase
AT01_2407	COG0156	8-amino-7-oxononanoate synthase activity
AT01_2408	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT01_241	COG0803	Belongs to the bacterial solute-binding protein 9 family
AT01_2410	COG0859	PFAM glycosyl transferase family 9
AT01_2411	COG1519	Transferase
AT01_2413	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AT01_2414	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AT01_2415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AT01_2416	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AT01_2417	COG2003	Belongs to the UPF0758 family
AT01_2418	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AT01_2419	COG0756	dUTP diphosphatase activity
AT01_2420	COG1309	transcriptional regulator
AT01_2421	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AT01_2422	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AT01_2423	COG1561	YicC-like family, N-terminal region
AT01_2424	COG5001	Diguanylate cyclase
AT01_2425	COG1024	Enoyl-CoA hydratase
AT01_2426	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AT01_2428	COG2860	membrane
AT01_2429	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AT01_2431	COG1758	RNA polymerase activity
AT01_2432	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AT01_2433	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AT01_2434	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AT01_2435	COG0786	glutamate:sodium symporter activity
AT01_2436	COG2233	PERMEase
AT01_2437	COG2982	Protein involved in outer membrane biogenesis
AT01_2446	COG3423	Transcriptional regulator
AT01_2447	COG0456	acetyltransferase
AT01_2449	COG1295	ribonuclease BN
AT01_2450	COG1011	Hydrolase
AT01_2452	COG0174	glutamine synthetase
AT01_2453	COG3852	Histidine kinase
AT01_2455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AT01_2458	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AT01_2458	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AT01_2459	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AT01_2460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AT01_2461	COG3084	Protein conserved in bacteria
AT01_2463	COG1763	Mo-molybdopterin cofactor biosynthetic process
AT01_2468	COG2186	Transcriptional regulator
AT01_2469	COG1609	Transcriptional regulator
AT01_247	COG1811	Na channel or pump
AT01_2470	COG0477	Major facilitator Superfamily
AT01_2471	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AT01_2472	COG1879	ABC-type sugar transport system periplasmic component
AT01_2473	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_2475	COG1869	D-ribose catabolic process
AT01_2476	COG3158	transport of potassium into the cell
AT01_2477	COG0714	Associated with various cellular activities
AT01_2478	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AT01_248	COG4249	Peptidase C14 caspase catalytic subunit p20
AT01_2480	COG2502	aspartate--ammonia ligase
AT01_2481	COG1522	sequence-specific DNA binding
AT01_2482	COG0716	FMN binding
AT01_2483	COG0445	tRNA wobble uridine modification
AT01_2484	COG0357	Ribosomal RNA small subunit methyltransferase G
AT01_2485	COG3312	ion transport
AT01_2486	COG0356	it plays a direct role in the translocation of protons across the membrane
AT01_2488	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AT01_2489	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AT01_2490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AT01_2492	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AT01_2493	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AT01_2494	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AT01_2495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AT01_2497	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AT01_2498	COG0573	inorganic phosphate transmembrane transporter activity
AT01_2499	COG0581	inorganic phosphate transmembrane transporter activity
AT01_25	COG3051	citrate lyase alpha subunit
AT01_250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AT01_2501	COG0704	Plays a role in the regulation of phosphate uptake
AT01_2502	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_2503	COG0765	amino acid transport
AT01_2504	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AT01_2505	COG0765	amino acid transport
AT01_2506	COG2252	PERMEase
AT01_2509	COG4191	Histidine kinase
AT01_251	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AT01_2510	COG0840	transmembrane signaling receptor activity
AT01_2511	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AT01_2512	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AT01_2513	COG0706	membrane insertase activity
AT01_2515	COG0594	ribonuclease P activity
AT01_2516	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AT01_2517	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AT01_2518	COG0592	DNA-directed DNA polymerase activity
AT01_252	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AT01_2520	COG0187	DNA topoisomerase II activity
AT01_2521	COG0561	phosphatase activity
AT01_2522	COG2423	ornithine cyclodeaminase activity
AT01_2523	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AT01_2524	COG0823	Involved in the tonB-independent uptake of proteins
AT01_2525	COG5645	(Lipo)protein
AT01_2528	COG0569	domain protein
AT01_2528	COG2985	domain, Protein
AT01_2529	COG3977	Valine--pyruvate aminotransferase
AT01_2533	COG2885	chlorophyll binding
AT01_2537	COG2818	Glycosylase
AT01_2538	COG0752	glycyl-tRNA synthetase alpha subunit
AT01_2539	COG0751	glycine-tRNA ligase activity
AT01_2542	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_2542	COG2213	PTS system mannitol-specific
AT01_2543	COG0246	Mannitol dehydrogenase
AT01_2545	COG3722	fumarate hydratase activity
AT01_2546	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT01_255	COG0776	regulation of translation
AT01_2550	COG2258	MOSC domain
AT01_2551	COG0840	transmembrane signaling receptor activity
AT01_2552	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AT01_2553	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AT01_2554	COG0243	molybdopterin cofactor binding
AT01_2554	COG3383	formate dehydrogenase (NAD+) activity
AT01_2555	COG0243	molybdopterin cofactor binding
AT01_2555	COG3383	formate dehydrogenase (NAD+) activity
AT01_2556	COG0437	4 iron, 4 sulfur cluster binding
AT01_2557	COG2864	formate dehydrogenase
AT01_2558	COG3058	Necessary for formate dehydrogenase activity
AT01_2559	COG1921	L-seryl-tRNASec selenium transferase activity
AT01_256	COG2314	TM2 domain
AT01_2560	COG3276	selenocysteine insertion sequence binding
AT01_2562	COG3550	peptidyl-serine autophosphorylation
AT01_2564	COG3274	enterobacterial common antigen metabolic process
AT01_257	COG4139	cobalamin transport
AT01_2570	COG3121	Chaperone
AT01_2571	COG1070	Carbohydrate kinase
AT01_2572	COG2115	Belongs to the xylose isomerase family
AT01_2573	COG4213	ABC transporter substrate-binding protein
AT01_2575	COG4214	carbohydrate transport
AT01_2576	COG1609	Transcriptional regulator
AT01_2576	COG2207	Transcriptional regulator
AT01_2578	COG0582	viral genome integration into host DNA
AT01_258	COG0386	Belongs to the glutathione peroxidase family
AT01_259	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AT01_2590	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AT01_2591	COG2986	histidine ammonia-lyase
AT01_2594	COG1764	response to oxidative stress
AT01_2595	COG2194	sulfuric ester hydrolase activity
AT01_2596	COG2197	response regulator
AT01_2598	COG2271	Major facilitator Superfamily
AT01_260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AT01_2600	COG0747	negative chemotaxis
AT01_2601	COG0601	transmembrane transport
AT01_2602	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT01_2603	COG0444	Belongs to the ABC transporter superfamily
AT01_2604	COG4608	Belongs to the ABC transporter superfamily
AT01_2605	COG2194	sulfuric ester hydrolase activity
AT01_2609	COG1192	Involved in chromosome partitioning
AT01_261	COG0463	Glycosyl transferase, family 2
AT01_2610	COG1215	transferase activity, transferring glycosyl groups
AT01_2611	COG1215	transferase activity, transferring glycosyl groups
AT01_2612	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AT01_2613	COG3118	belongs to the thioredoxin family
AT01_2613	COG0457	Tetratricopeptide repeat
AT01_2614	COG2200	EAL domain
AT01_2614	COG2199	diguanylate cyclase activity
AT01_2615	COG1301	dicarboxylic acid transport
AT01_2616	COG0612	Peptidase, M16
AT01_2617	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AT01_2618	COG1942	4-Oxalocrotonate Tautomerase
AT01_2619	COG2200	EAL domain
AT01_2620	COG2982	Protein involved in outer membrane biogenesis
AT01_2621	COG2134	cdp-diacylglycerol pyrophosphatase
AT01_2622	COG1295	ribonuclease BN
AT01_2624	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AT01_2625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AT01_2627	COG0742	ribosomal rna small subunit methyltransferase
AT01_263	COG0726	polysaccharide deacetylase
AT01_2631	COG0589	response to stress
AT01_2633	COG0306	phosphate transporter
AT01_2638	COG3718	enzyme involved in inositol metabolism
AT01_264	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AT01_2640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AT01_2641	COG3962	Belongs to the TPP enzyme family
AT01_2642	COG0673	inositol 2-dehydrogenase activity
AT01_2643	COG1082	Xylose isomerase domain protein TIM barrel
AT01_2644	COG1082	Xylose isomerase domain protein TIM barrel
AT01_2645	COG1247	-acetyltransferase
AT01_2646	COG1741	Belongs to the pirin family
AT01_2647	COG1609	Transcriptional regulator
AT01_2648	COG2610	gluconate transmembrane transporter activity
AT01_2649	COG3265	gluconokinase activity
AT01_265	COG2076	Multidrug Resistance protein
AT01_2650	COG2095	MarC family integral membrane protein
AT01_2651	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AT01_2659	COG3275	phosphorelay sensor kinase activity
AT01_266	COG2076	Multidrug Resistance protein
AT01_2661	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AT01_2662	COG1523	belongs to the glycosyl hydrolase 13 family
AT01_2663	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AT01_2664	COG0297	glycogen (starch) synthase activity
AT01_2665	COG0058	SHG alpha-glucan phosphorylase activity
AT01_2666	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AT01_2667	COG1349	DNA-binding transcription factor activity
AT01_2668	COG0705	Rhomboid family
AT01_267	COG0791	NLP P60 protein
AT01_2671	COG2909	trisaccharide binding
AT01_2672	COG0058	SHG alpha-glucan phosphorylase activity
AT01_2675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AT01_2675	COG0316	Belongs to the HesB IscA family
AT01_2677	COG0596	Alpha beta hydrolase
AT01_268	COG0095	Lipoate-protein ligase
AT01_2681	COG1918	ferrous iron import across plasma membrane
AT01_2682	COG2183	response to ionizing radiation
AT01_2685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AT01_2686	COG0745	RESPONSE REGULATOR receiver
AT01_2688	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AT01_2690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AT01_2691	COG1011	Hydrolase
AT01_2693	COG0494	nUDIX hydrolase
AT01_2694	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AT01_2699	COG4796	Type ii and iii secretion system protein
AT01_270	COG4558	Periplasmic binding protein
AT01_2700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AT01_2704	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AT01_2706	COG0180	Tryptophanyl-tRNA synthetase
AT01_2707	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AT01_2707	COG1648	precorrin-2 dehydrogenase activity
AT01_2709	COG2146	nitrite reductase [NAD(P)H] activity
AT01_271	COG3720	iron ion transport
AT01_2710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AT01_2711	COG0402	S-adenosylhomocysteine deaminase activity
AT01_2712	COG0738	Major facilitator superfamily
AT01_2716	COG1486	melibiose metabolic process
AT01_2717	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AT01_2718	COG0433	COG0433 Predicted ATPase
AT01_272	COG4771	TonB-dependent receptor
AT01_2723	COG1765	OsmC-like protein
AT01_2724	COG3954	Phosphoribulokinase
AT01_2726	COG0429	hydrolase of the alpha beta-hydrolase fold
AT01_2730	COG1216	Glycosyl transferase, family 2
AT01_2731	COG0488	(ABC) transporter
AT01_2732	COG2249	NAD(P)H dehydrogenase (quinone) activity
AT01_2734	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AT01_2735	COG1047	Peptidyl-prolyl cis-trans
AT01_2737	COG0545	Peptidyl-prolyl cis-trans isomerase
AT01_2738	COG2964	Protein conserved in bacteria
AT01_2739	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AT01_274	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AT01_2741	COG2168	tRNA wobble position uridine thiolation
AT01_2742	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AT01_2743	COG0049	tRNA binding
AT01_2745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AT01_2748	COG0051	transcription antitermination factor activity, RNA binding
AT01_275	COG0574	Belongs to the PEP-utilizing enzyme family
AT01_275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AT01_2751	COG0089	rRNA binding
AT01_2752	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AT01_2753	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AT01_2754	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AT01_2755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AT01_2756	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AT01_2757	COG0255	Belongs to the universal ribosomal protein uL29 family
AT01_2758	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AT01_2759	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AT01_276	COG0628	permease
AT01_2762	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AT01_2764	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AT01_2766	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AT01_2767	COG1841	ribosomal large subunit assembly
AT01_2768	COG0200	Binds to the 23S rRNA
AT01_2769	COG0201	protein transport
AT01_277	COG0277	FAD linked oxidase domain protein
AT01_277	COG0247	lactate metabolic process
AT01_2770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AT01_2771	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AT01_2772	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AT01_2773	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AT01_2775	COG0203	ribosomal protein L17
AT01_2776	COG0789	Transcriptional regulator
AT01_2777	COG3036	rescue of stalled ribosome
AT01_2778	COG1970	mechanosensitive ion channel activity
AT01_2779	COG0569	domain protein
AT01_278	COG2050	protein possibly involved in aromatic compounds catabolism
AT01_2780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AT01_2780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AT01_2781	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AT01_2782	COG0242	peptide deformylase activity
AT01_2783	COG0758	DNA mediated transformation
AT01_2788	COG5301	cellulose 1,4-beta-cellobiosidase activity
AT01_279	COG0316	Belongs to the HesB IscA family
AT01_28	COG0471	metal ion transport
AT01_280	COG0719	Fe-S assembly protein
AT01_2808	COG4695	Portal protein
AT01_281	COG0396	ATPase activity
AT01_282	COG0719	Fe-S assembly protein
AT01_2823	COG4974	Belongs to the 'phage' integrase family
AT01_2825	COG0551	DNA topoisomerase type I activity
AT01_2826	COG0009	L-threonylcarbamoyladenylate synthase
AT01_2827	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AT01_2828	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AT01_2834	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AT01_2835	COG3162	membrane
AT01_2836	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AT01_2837	COG1301	dicarboxylic acid transport
AT01_2841	COG3264	Mechanosensitive ion channel
AT01_2841	COG1511	domain protein
AT01_2843	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT01_2844	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AT01_2845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT01_2846	COG4558	Periplasmic binding protein
AT01_2847	COG3720	iron ion transport
AT01_2848	COG4771	TonB-dependent receptor
AT01_285	COG1388	LysM domain
AT01_285	COG1376	ErfK ybiS ycfS ynhG family protein
AT01_2853	COG4607	ABC-type enterochelin transport system periplasmic component
AT01_2855	COG4605	iron ion homeostasis
AT01_2856	COG4604	ABC transporter, ATP-binding protein
AT01_2857	COG3443	Belongs to the bacterial solute-binding protein 9 family
AT01_2859	COG0814	amino acid
AT01_286	COG4238	major outer membrane lipoprotein
AT01_2860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AT01_2861	COG1882	Formate acetyltransferase
AT01_2865	COG2197	response regulator
AT01_2866	COG3539	Fimbrial protein
AT01_2870	COG3539	Fimbrial protein
AT01_2873	COG3121	Chaperone
AT01_2878	COG1309	transcriptional regulator
AT01_2879	COG2084	Dehydrogenase
AT01_2880	COG2084	Dehydrogenase
AT01_2881	COG1929	Belongs to the glycerate kinase type-1 family
AT01_2882	COG4232	protein-disulfide reductase activity
AT01_2884	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AT01_2887	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AT01_2891	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AT01_2894	COG2076	Multidrug Resistance protein
AT01_2896	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AT01_2897	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AT01_2898	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AT01_2899	COG1053	succinate dehydrogenase
AT01_2901	COG3264	Mechanosensitive ion channel
AT01_2901	COG1511	domain protein
AT01_2903	COG1162	GTPase activity
AT01_2904	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AT01_2908	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AT01_2909	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AT01_2909	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AT01_291	COG0534	Mate efflux family protein
AT01_2910	COG0802	atpase or kinase
AT01_2911	COG0860	N-Acetylmuramoyl-L-alanine amidase
AT01_2912	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AT01_2913	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AT01_2914	COG1923	regulation of RNA biosynthetic process
AT01_2915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AT01_2916	COG0330	HflC and HflK could
AT01_2917	COG0330	HflC and HflK could
AT01_2918	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AT01_2919	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AT01_292	COG0307	riboflavin synthase, alpha
AT01_2920	COG1959	2 iron, 2 sulfur cluster binding
AT01_2921	COG0557	exoribonuclease II activity
AT01_2922	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AT01_2923	COG1960	acyl-CoA dehydrogenase activity
AT01_2924	COG3650	response to hydrogen peroxide
AT01_2925	COG1073	alpha beta
AT01_2926	COG0360	Binds together with S18 to 16S ribosomal RNA
AT01_2927	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AT01_2928	COG0359	binds to the 23S rRNA
AT01_293	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AT01_2930	COG3061	Opacity-associated protein A
AT01_2931	COG0545	Peptidyl-prolyl cis-trans isomerase
AT01_2933	COG0737	Belongs to the 5'-nucleotidase family
AT01_2934	COG1218	3'(2'),5'-bisphosphate nucleotidase
AT01_2935	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AT01_2938	COG1253	flavin adenine dinucleotide binding
AT01_2939	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AT01_294	COG2814	Major facilitator Superfamily
AT01_2940	COG0729	surface antigen
AT01_2941	COG2911	Protein conserved in bacteria
AT01_2942	COG2105	PFAM AIG2 family protein
AT01_2943	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AT01_2945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AT01_2949	COG3423	Transcriptional regulator
AT01_295	COG0583	DNA-binding transcription factor activity
AT01_2952	COG0142	geranyltranstransferase activity
AT01_2953	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AT01_2954	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AT01_2955	COG0697	spore germination
AT01_2956	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AT01_2957	COG0642	Histidine kinase
AT01_2958	COG0745	RESPONSE REGULATOR receiver
AT01_2959	COG2027	D-alanyl-D-alanine carboxypeptidase
AT01_296	COG1609	Transcriptional regulator
AT01_2960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AT01_2961	COG1534	Rna-binding protein
AT01_2962	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AT01_2963	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AT01_2964	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AT01_2966	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AT01_2970	COG0195	Participates in both transcription termination and antitermination
AT01_2972	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AT01_2973	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AT01_2975	COG1185	polyribonucleotide nucleotidyltransferase activity
AT01_2977	COG0513	Belongs to the DEAD box helicase family
AT01_2978	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AT01_298	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AT01_2983	COG2827	Endonuclease containing a URI domain
AT01_2984	COG3153	acetyltransferase
AT01_2985	COG0531	amino acid
AT01_2986	COG1982	Orn Lys Arg decarboxylase major
AT01_2987	COG3787	Belongs to the UPF0306 family
AT01_2988	COG0702	epimerase
AT01_2989	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AT01_299	COG0791	NLP P60 protein
AT01_2990	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AT01_2991	COG3454	Phosphonate metabolism
AT01_2992	COG4778	phosphonate C-P lyase system protein PhnL
AT01_2993	COG4107	phosphonate C-P lyase system protein PhnK
AT01_2994	COG3627	carbon phosphorus lyase activity
AT01_2995	COG3626	phosphonate metabolism
AT01_2996	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AT01_2997	COG3624	Phosphonate C-P lyase system protein PhnG
AT01_2998	COG2188	Transcriptional regulator
AT01_300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AT01_3001	COG0583	DNA-binding transcription factor activity
AT01_3002	COG2249	NAD(P)H dehydrogenase (quinone) activity
AT01_3005	COG4608	Belongs to the ABC transporter superfamily
AT01_3006	COG0444	Belongs to the ABC transporter superfamily
AT01_3007	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT01_3008	COG0601	transmembrane transport
AT01_301	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AT01_3010	COG2731	YhcH YjgK YiaL family protein
AT01_3012	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AT01_3015	COG2927	DNA polymerase III (CHI subunit)
AT01_3016	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AT01_3017	COG0795	lipopolysaccharide-transporting ATPase activity
AT01_3018	COG0795	lipopolysaccharide-transporting ATPase activity
AT01_302	COG0346	lactoylglutathione lyase activity
AT01_3021	COG3077	Addiction module antitoxin, RelB DinJ family
AT01_3024	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AT01_3029	COG3210	domain, Protein
AT01_303	COG1902	pentaerythritol trinitrate reductase activity
AT01_3030	COG2831	hemolysin activation secretion protein
AT01_3033	COG0583	DNA-binding transcription factor activity
AT01_304	COG1309	transcriptional regulator
AT01_3040	COG3272	Protein of unknown function (DUF1722)
AT01_3041	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AT01_3042	COG1830	Aldolase
AT01_3043	COG1879	ABC-type sugar transport system periplasmic component
AT01_3044	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_3045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_3046	COG1129	ABC transporter
AT01_3047	COG2390	Transcriptional regulator
AT01_3048	COG1070	Carbohydrate kinase
AT01_3049	COG0859	PFAM glycosyl transferase family 9
AT01_305	COG2194	sulfuric ester hydrolase activity
AT01_3052	COG2235	arginine
AT01_3054	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT01_3055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT01_306	COG3313	Fe-S protein
AT01_3060	COG2376	Dihydroxyacetone kinase
AT01_3061	COG1461	Dihydroxyacetone kinase
AT01_3062	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AT01_3062	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AT01_3062	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_3064	COG2192	nodulation
AT01_3069	COG3284	Transcriptional regulator
AT01_307	COG4989	oxidoreductase activity
AT01_3076	COG3706	GGDEF domain
AT01_308	COG1289	transmembrane transporter activity
AT01_3082	COG0667	Aldo Keto reductase
AT01_3084	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AT01_3085	COG0456	acetyltransferase
AT01_3086	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AT01_3087	COG2823	Periplasmic or secreted lipoprotein
AT01_3089	COG4667	esterase of the alpha-beta hydrolase superfamily
AT01_309	COG1566	PFAM secretion protein HlyD family protein
AT01_3090	COG0084	hydrolase, TatD family'
AT01_3091	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AT01_3092	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AT01_3094	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AT01_3095	COG0813	purine-nucleoside phosphorylase activity
AT01_3096	COG3726	membrane protein affecting hemolysin expression
AT01_3097	COG0560	Phosphoserine phosphatase
AT01_31	COG2814	Major facilitator Superfamily
AT01_3101	COG1454	alcohol dehydrogenase
AT01_3108	COG0488	(ABC) transporter
AT01_3109	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AT01_311	COG1846	Transcriptional regulator
AT01_3110	COG0741	lytic transglycosylase activity
AT01_3111	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AT01_3112	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AT01_3113	COG2207	Transcriptional regulator
AT01_3113	COG3708	Transcriptional regulator
AT01_3115	COG3045	CreA protein
AT01_3116	COG0745	RESPONSE REGULATOR receiver
AT01_3118	COG0083	homoserine kinase activity
AT01_312	COG3133	Outer membrane lipoprotein
AT01_3120	COG3022	response to hydroperoxide
AT01_3121	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AT01_3122	COG0521	Mo-molybdopterin cofactor biosynthetic process
AT01_3124	COG1584	GPR1 FUN34 yaaH family protein
AT01_3126	COG0484	heat shock protein binding
AT01_3127	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AT01_3128	COG0583	DNA-binding transcription factor activity
AT01_313	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AT01_3130	COG0196	riboflavin kinase activity
AT01_3131	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AT01_3132	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AT01_3133	COG1047	Peptidyl-prolyl cis-trans
AT01_3134	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AT01_3136	COG0505	Belongs to the CarA family
AT01_3137	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AT01_3138	COG1280	lysine exporter protein (LysE YggA)
AT01_3139	COG2966	Psort location CytoplasmicMembrane, score
AT01_314	COG3895	Periplasmic Protein
AT01_3141	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AT01_3142	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AT01_3145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AT01_3146	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AT01_3147	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AT01_3148	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AT01_3149	COG0564	pseudouridine synthase activity
AT01_3152	COG3157	Type VI secretion system effector, Hcp
AT01_3155	COG1388	LysM domain
AT01_3155	COG1470	cell adhesion involved in biofilm formation
AT01_3159	COG1289	transmembrane transporter activity
AT01_316	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AT01_3161	COG0642	Histidine kinase
AT01_3166	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AT01_3167	COG0417	DNA replication proofreading
AT01_3169	COG0586	Pfam SNARE associated Golgi protein
AT01_3171	COG1178	ABC-type Fe3 transport system permease component
AT01_3172	COG4143	(ABC) transporter
AT01_3175	COG4533	DNA binding
AT01_3176	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AT01_3179	COG2814	Major facilitator Superfamily
AT01_3181	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AT01_3182	COG0473	3-isopropylmalate dehydrogenase activity
AT01_3183	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AT01_3185	COG1022	Amp-dependent synthetase and ligase
AT01_3186	COG0028	Belongs to the TPP enzyme family
AT01_3188	COG1609	Transcriptional regulator
AT01_319	COG0625	glutathione transferase activity
AT01_3191	COG0275	rRNA processing
AT01_3192	COG3116	cell division
AT01_3193	COG0768	penicillin binding
AT01_3194	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AT01_3195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AT01_3196	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AT01_3198	COG0772	Belongs to the SEDS family
AT01_3199	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AT01_3200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AT01_3202	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AT01_3203	COG0849	cell division
AT01_3204	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AT01_3208	COG0653	protein targeting
AT01_3209	COG0494	nUDIX hydrolase
AT01_3210	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AT01_3212	COG0237	dephospho-CoA kinase activity
AT01_3213	COG0516	GMP reductase activity
AT01_3214	COG1459	type II secretion system
AT01_3215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AT01_3216	COG4969	Belongs to the N-Me-Phe pilin family
AT01_3219	COG3725	Membrane protein required for beta-lactamase induction
AT01_3221	COG3940	Belongs to the glycosyl hydrolase 43 family
AT01_3222	COG2211	Major facilitator Superfamily
AT01_3223	COG1113	amino acid transport
AT01_3224	COG2186	Transcriptional regulator
AT01_3225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AT01_3226	COG0508	dehydrogenase complex catalyzes the overall conversion of
AT01_3227	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AT01_323	COG3104	oligopeptide transport
AT01_3232	COG3112	Uncharacterised protein family (UPF0231)
AT01_3233	COG0697	spore germination
AT01_3234	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AT01_3235	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AT01_3237	COG2132	Multicopper oxidase
AT01_3239	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AT01_3240	COG0288	reversible hydration of carbon dioxide
AT01_3241	COG1131	(ABC) transporter
AT01_3242	COG0842	Transport permease protein
AT01_3243	COG0726	polysaccharide deacetylase
AT01_3244	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AT01_3245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AT01_3246	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AT01_3247	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AT01_3248	COG0617	tRNA 3'-terminal CCA addition
AT01_325	COG4172	Belongs to the ABC transporter superfamily
AT01_3251	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AT01_3252	COG1489	DNA binding
AT01_3253	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AT01_3254	COG1643	Atp-dependent helicase
AT01_3255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AT01_3256	COG1120	ATPase activity
AT01_3257	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AT01_3258	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AT01_3259	COG2223	nitrite transmembrane transporter activity
AT01_326	COG4172	Belongs to the ABC transporter superfamily
AT01_3260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AT01_3262	COG0316	Belongs to the HesB IscA family
AT01_3263	COG2860	membrane
AT01_3266	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AT01_3267	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AT01_3268	COG4999	Histidine kinase
AT01_3268	COG3437	response regulator, receiver
AT01_3268	COG3850	Histidine kinase
AT01_3268	COG2205	protein histidine kinase activity
AT01_327	COG4171	peptide transport system, permease
AT01_3270	COG4999	Histidine kinase
AT01_3270	COG3437	response regulator, receiver
AT01_3270	COG3850	Histidine kinase
AT01_3270	COG2205	protein histidine kinase activity
AT01_3271	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AT01_3272	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AT01_3273	COG3956	TIGRFAM MazG family protein
AT01_3274	COG0504	CTP synthase activity
AT01_3275	COG0148	phosphopyruvate hydratase activity
AT01_3278	COG0602	queuosine metabolic process
AT01_3279	COG0720	synthase
AT01_328	COG4168	peptide transport system, permease
AT01_3280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AT01_3281	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AT01_3282	COG0175	sulfate reduction
AT01_3285	COG2234	aminopeptidase activity
AT01_3286	COG1648	precorrin-2 dehydrogenase activity
AT01_3286	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AT01_3287	COG0175	sulfate reduction
AT01_3288	COG2895	sulfate adenylyltransferase (ATP) activity
AT01_3289	COG0529	Catalyzes the synthesis of activated sulfate
AT01_329	COG4166	transmembrane transport
AT01_3292	COG0765	amino acid transport
AT01_3294	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AT01_3296	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AT01_3297	COG0585	pseudouridine synthase activity
AT01_3298	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AT01_3299	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AT01_3300	COG4942	peptidase
AT01_3300	COG1388	LysM domain
AT01_3301	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AT01_3302	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AT01_3309	COG3188	usher protein
AT01_3310	COG3121	Chaperone
AT01_3311	COG3539	Fimbrial protein
AT01_3312	COG3539	Fimbrial protein
AT01_3319	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT01_332	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AT01_3320	COG1136	(ABC) transporter
AT01_3320	COG0577	efflux transmembrane transporter activity
AT01_3321	COG1538	Outer membrane efflux protein
AT01_3325	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_3326	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_3327	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AT01_3329	COG3048	D-serine ammonia-lyase activity
AT01_333	COG1842	Phage shock protein A
AT01_3330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AT01_3331	COG0640	Transcriptional regulator
AT01_3332	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AT01_3332	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AT01_3333	COG1349	DNA-binding transcription factor activity
AT01_3335	COG1070	Carbohydrate kinase
AT01_3336	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
AT01_3337	COG0738	Major facilitator superfamily
AT01_3338	COG0235	Class ii aldolase
AT01_3339	COG1454	alcohol dehydrogenase
AT01_3340	COG0243	molybdopterin cofactor binding
AT01_3341	COG0437	4 iron, 4 sulfur cluster binding
AT01_3342	COG3302	dmso reductase anchor subunit
AT01_3343	COG3381	protein complex oligomerization
AT01_3348	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AT01_3349	COG2137	regulation of response to DNA damage stimulus
AT01_335	COG1983	PspC domain protein
AT01_3350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AT01_3351	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AT01_3356	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AT01_3357	COG1238	metal cluster binding
AT01_3358	COG2918	glutathione biosynthetic process
AT01_3359	COG1854	S-ribosylhomocysteine lyase activity
AT01_3360	COG4536	flavin adenine dinucleotide binding
AT01_3361	COG4137	Cytochrome C assembly protein
AT01_3362	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AT01_3363	COG0228	four-way junction DNA binding
AT01_3364	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AT01_3365	COG0336	Belongs to the RNA methyltransferase TrmD family
AT01_3366	COG0335	large ribosomal subunit rRNA binding
AT01_3367	COG3137	Salt-induced outer membrane protein
AT01_3368	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AT01_3369	COG3279	Response regulator of the LytR AlgR family
AT01_337	COG3106	COG3106 Predicted ATPase
AT01_3370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AT01_3371	COG0287	Prephenate dehydrogenase
AT01_3371	COG1605	Chorismate mutase
AT01_3372	COG0077	Prephenate dehydratase
AT01_3372	COG1605	Chorismate mutase
AT01_3373	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AT01_3374	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AT01_3375	COG0564	pseudouridine synthase activity
AT01_3377	COG0542	response to heat
AT01_338	COG3768	UPF0283 membrane protein
AT01_3387	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AT01_3388	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AT01_3399	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_3401	COG3021	interspecies interaction between organisms
AT01_3404	COG0741	lytic transglycosylase activity
AT01_3404	COG1388	LysM domain
AT01_3405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AT01_3406	COG2226	methyltransferase
AT01_3408	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AT01_3412	COG2113	Glycine betaine
AT01_3413	COG4176	ABC-type proline glycine betaine transport system permease component
AT01_3414	COG4175	Glycine betaine
AT01_3415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AT01_3419	COG4575	ribosome binding
AT01_342	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AT01_3422	COG2207	Transcriptional regulator
AT01_3423	COG0477	Major facilitator Superfamily
AT01_3427	COG1278	Cold shock
AT01_3429	COG0747	negative chemotaxis
AT01_343	COG2866	Carboxypeptidase
AT01_3430	COG0601	transmembrane transport
AT01_3431	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT01_3433	COG1124	(ABC) transporter
AT01_3434	COG0831	urea catabolic process
AT01_3436	COG0804	urea catabolic process
AT01_3437	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AT01_3438	COG0830	nickel cation binding
AT01_3439	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AT01_344	COG4948	Mandelate Racemase Muconate Lactonizing
AT01_3440	COG0829	nickel cation binding
AT01_3441	COG4413	Urea transporter
AT01_3442	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AT01_3444	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AT01_3445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AT01_3447	COG2133	pyrroloquinoline quinone binding
AT01_3448	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AT01_3449	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AT01_345	COG4166	transmembrane transport
AT01_3450	COG2723	6-phospho-beta-galactosidase activity
AT01_3451	COG1447	Phosphotransferase system cellobiose-specific component IIA
AT01_3452	COG1917	Cupin 2, conserved barrel domain protein
AT01_3452	COG2169	Transcriptional regulator
AT01_3453	COG3394	polysaccharide catabolic process
AT01_3455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AT01_3465	COG0210	DNA helicase
AT01_3466	COG0582	viral genome integration into host DNA
AT01_3467	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AT01_3468	COG2867	negative regulation of translational initiation
AT01_347	COG0598	Magnesium transport protein CorA
AT01_3470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AT01_3471	COG0497	DNA recombination
AT01_3472	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AT01_3475	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AT01_348	COG0037	tRNA processing
AT01_3481	COG0513	Belongs to the DEAD box helicase family
AT01_3483	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AT01_3485	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AT01_3486	COG3026	antisigma factor binding
AT01_3487	COG3086	response to oxidative stress
AT01_349	COG0823	Involved in the tonB-independent uptake of proteins
AT01_3490	COG0481	GTPase activity
AT01_3491	COG0681	Belongs to the peptidase S26 family
AT01_3492	COG0571	ribonuclease III activity
AT01_3493	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AT01_3494	COG1381	Involved in DNA repair and RecF pathway recombination
AT01_3495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AT01_3496	COG0736	holo-[acyl-carrier-protein] synthase activity
AT01_3497	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AT01_3498	COG1737	Transcriptional regulator
AT01_350	COG0674	pyruvate-flavodoxin oxidoreductase activity
AT01_350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT01_350	COG1013	pyruvate-flavodoxin oxidoreductase activity
AT01_350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AT01_3500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AT01_3500	COG1263	PTS System
AT01_3501	COG0560	Phosphoserine phosphatase
AT01_3503	COG0590	tRNA wobble adenosine to inosine editing
AT01_3504	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AT01_3506	COG1105	Belongs to the carbohydrate kinase PfkB family
AT01_3509	COG2205	protein histidine kinase activity
AT01_3510	COG3170	Tfp pilus assembly protein FimV
AT01_3511	COG2204	response regulator
AT01_3512	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AT01_3512	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AT01_3513	COG0347	Belongs to the P(II) protein family
AT01_3516	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AT01_3519	COG2188	Transcriptional regulator
AT01_352	COG1285	pathogenesis
AT01_3520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AT01_3520	COG1017	nitric oxide dioxygenase activity
AT01_3522	COG3711	transcriptional antiterminator
AT01_3523	COG2814	Major facilitator Superfamily
AT01_3525	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AT01_3526	COG0483	inositol monophosphate 1-phosphatase activity
AT01_3527	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AT01_3528	COG1959	2 iron, 2 sulfur cluster binding
AT01_353	COG3042	response to heat
AT01_3530	COG0822	iron-sulfur transferase activity
AT01_3531	COG0316	Belongs to the HesB IscA family
AT01_3532	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AT01_3533	COG0443	Heat shock 70 kDa protein
AT01_3534	COG0633	Ferredoxin
AT01_3535	COG2975	iron-sulfur cluster assembly
AT01_3538	COG2373	Large extracellular alpha-helical protein
AT01_3539	COG4953	penicillin-binding protein 1C
AT01_354	COG3187	Heat shock protein
AT01_3541	COG0105	UTP biosynthetic process
AT01_3542	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AT01_3544	COG1426	Protein conserved in bacteria
AT01_3546	COG0124	histidyl-tRNA synthetase
AT01_3547	COG2976	Protein conserved in bacteria
AT01_3548	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AT01_355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AT01_3551	COG1645	bacterial-type flagellum-dependent swarming motility
AT01_3552	COG1570	exodeoxyribonuclease VII activity
AT01_3553	COG0516	GMP reductase activity
AT01_3553	COG0517	IMP dehydrogenase activity
AT01_3554	COG0519	Catalyzes the synthesis of GMP from XMP
AT01_3554	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AT01_356	COG2911	Protein conserved in bacteria
AT01_3560	COG0351	phosphomethylpyrimidine kinase
AT01_3564	COG1349	DNA-binding transcription factor activity
AT01_3565	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_3566	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_3569	COG3730	PTS system glucitol sorbitol-specific
AT01_3570	COG1597	lipid kinase activity
AT01_3572	COG3422	double-strand break repair
AT01_3573	COG0745	RESPONSE REGULATOR receiver
AT01_3574	COG2205	protein histidine kinase activity
AT01_3575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT01_3577	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT01_358	COG3784	Protein of unknown function (DUF1318)
AT01_3582	COG3121	Chaperone
AT01_3584	COG0443	Heat shock 70 kDa protein
AT01_3585	COG5002	protein histidine kinase activity
AT01_3585	COG5001	Diguanylate cyclase
AT01_3585	COG3447	MASE1 domain protein
AT01_3586	COG2239	Acts as a magnesium transporter
AT01_3588	COG0248	Ppx GppA phosphatase
AT01_3589	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AT01_359	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AT01_3591	COG0581	inorganic phosphate transmembrane transporter activity
AT01_3593	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AT01_3594	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AT01_3595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AT01_3597	COG2233	PERMEase
AT01_3598	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AT01_3599	COG1393	Belongs to the ArsC family
AT01_360	COG1643	Atp-dependent helicase
AT01_3600	COG4783	chaperone-mediated protein folding
AT01_3601	COG0628	permease
AT01_3602	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AT01_3603	COG2716	regulation of RNA biosynthetic process
AT01_3604	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AT01_3605	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AT01_3607	COG2321	neutral zinc metallopeptidase
AT01_361	COG3344	reverse transcriptase
AT01_3611	COG1876	peptidase activity
AT01_3612	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AT01_3613	COG1393	Belongs to the ArsC family
AT01_3615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AT01_3617	COG2197	response regulator
AT01_3618	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AT01_3618	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AT01_3619	COG3062	negative regulation of establishment of protein localization
AT01_3620	COG0243	molybdopterin cofactor binding
AT01_3621	COG3043	anaerobic respiration
AT01_3622	COG3005	denitrification pathway
AT01_3625	COG1671	Belongs to the UPF0178 family
AT01_3628	COG3111	PFAM Bacterial OB fold (BOF) protein
AT01_3630	COG2837	iron assimilation
AT01_3631	COG4150	thiosulfate binding
AT01_3632	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AT01_3633	COG4208	sulfate ABC transporter
AT01_3636	COG1136	(ABC) transporter
AT01_3636	COG0577	efflux transmembrane transporter activity
AT01_3637	COG2205	protein histidine kinase activity
AT01_3638	COG2190	(PTS) system
AT01_3640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_3641	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AT01_3642	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AT01_3644	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AT01_3645	COG3530	Putative quorum-sensing-regulated virulence factor
AT01_365	COG3046	protein related to deoxyribodipyrimidine photolyase
AT01_3650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AT01_3655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AT01_3656	COG1914	H( )-stimulated, divalent metal cation uptake system
AT01_3658	COG0667	Aldo Keto reductase
AT01_3659	COG3961	Belongs to the TPP enzyme family
AT01_3663	COG2223	nitrite transmembrane transporter activity
AT01_3664	COG3279	Response regulator of the LytR AlgR family
AT01_3665	COG3275	phosphorelay sensor kinase activity
AT01_3668	COG0436	Aminotransferase
AT01_3669	COG3038	cytochrome b561
AT01_3670	COG1598	PFAM Uncharacterised protein family UPF0150
AT01_3678	COG2951	lytic endotransglycosylase activity
AT01_3679	COG0531	amino acid
AT01_3683	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AT01_3684	COG1127	ABC transporter
AT01_3688	COG0626	cystathionine gamma-synthase activity
AT01_369	COG3316	Transposase and inactivated derivatives
AT01_3690	COG3038	cytochrome b561
AT01_3691	COG2353	YceI-like domain
AT01_3693	COG1695	Transcriptional regulator
AT01_3697	COG2979	Protein of unknown function (DUF533)
AT01_370	COG0740	serine-type endopeptidase activity
AT01_3701	COG2801	Transposase and inactivated derivatives
AT01_3703	COG2963	transposase activity
AT01_3704	COG2963	transposase activity
AT01_3707	COG2850	peptidyl-arginine hydroxylation
AT01_3711	COG3121	Chaperone
AT01_3714	COG2197	response regulator
AT01_3718	COG5265	(ABC) transporter
AT01_3722	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AT01_3725	COG2197	response regulator
AT01_3726	COG1278	Cold shock
AT01_3727	COG1278	Cold shock
AT01_3728	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AT01_3729	COG3706	GGDEF domain
AT01_3730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AT01_3731	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AT01_3732	COG0321	lipoyl(octanoyl) transferase activity
AT01_3734	COG1686	Belongs to the peptidase S11 family
AT01_3735	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AT01_3736	COG0772	Belongs to the SEDS family
AT01_3737	COG0768	penicillin binding
AT01_3739	COG0799	negative regulation of ribosome biogenesis
AT01_3740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AT01_3741	COG1466	dna polymerase III delta subunit
AT01_3742	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AT01_3744	COG2888	peptidyl-tyrosine sulfation
AT01_3745	COG1126	abc transporter atp-binding protein
AT01_3746	COG0765	amino acid transport
AT01_3747	COG0765	amino acid transport
AT01_3750	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AT01_3751	COG4535	Mg2 and Co2 transporter CorC
AT01_3752	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AT01_3753	COG1702	phosphate starvation-inducible protein PhoH
AT01_3754	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AT01_3755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AT01_3762	COG0367	asparagine synthase
AT01_3763	COG0647	UMP catabolic process
AT01_3764	COG1846	Transcriptional regulator
AT01_3764	COG1940	carbohydrate kinase activity
AT01_3765	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AT01_3766	COG0363	glucosamine-6-phosphate deaminase activity
AT01_3767	COG1263	PTS System
AT01_3767	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AT01_3767	COG2190	(PTS) system
AT01_3768	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AT01_3772	COG0735	belongs to the Fur family
AT01_3775	COG0840	transmembrane signaling receptor activity
AT01_3778	COG0596	Alpha beta hydrolase
AT01_3779	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AT01_3780	COG0033	Phosphoglucomutase
AT01_3782	COG0745	RESPONSE REGULATOR receiver
AT01_3783	COG2205	protein histidine kinase activity
AT01_3784	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AT01_3785	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AT01_3788	COG3272	Protein of unknown function (DUF1722)
AT01_3790	COG5212	phosphodiesterase
AT01_3791	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AT01_3792	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AT01_3793	COG1984	allophanate hydrolase subunit 2
AT01_3794	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AT01_3799	COG2009	succinate dehydrogenase
AT01_38	COG3121	Chaperone
AT01_380	COG3344	reverse transcriptase
AT01_3800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AT01_3801	COG1053	succinate dehydrogenase
AT01_3803	COG0567	Dehydrogenase, E1 component
AT01_3804	COG0508	dehydrogenase complex catalyzes the overall conversion of
AT01_3806	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AT01_3807	COG0737	Belongs to the 5'-nucleotidase family
AT01_3808	COG1271	oxidase subunit
AT01_3809	COG1294	oxidase, subunit
AT01_3810	COG4890	Cyd operon protein YbgT
AT01_3811	COG3790	cyd operon protein YbgE
AT01_3812	COG0824	Thioesterase
AT01_3813	COG0811	peptide transport
AT01_3814	COG0848	biopolymer transport protein
AT01_3815	COG3064	Membrane
AT01_3815	COG3064	Membrane
AT01_3816	COG0823	Involved in the tonB-independent uptake of proteins
AT01_3817	COG2885	chlorophyll binding
AT01_3818	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AT01_3823	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AT01_3825	COG1230	cation diffusion facilitator family transporter
AT01_3826	COG2205	protein histidine kinase activity
AT01_3826	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_3827	COG2197	response regulator
AT01_3828	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AT01_3829	COG0588	phosphoglycerate mutase activity
AT01_383	COG3591	Belongs to the peptidase S1B family
AT01_3831	COG2017	converts alpha-aldose to the beta-anomer
AT01_3832	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AT01_3834	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AT01_3836	COG1119	ATPase activity
AT01_3837	COG3585	molybdate ion transport
AT01_3837	COG2005	Transcriptional regulator
AT01_3839	COG0725	ABC transporter, periplasmic molybdate-binding protein
AT01_3840	COG4149	molybdate abc transporter
AT01_3842	COG0561	phosphatase activity
AT01_3846	COG0156	8-amino-7-oxononanoate synthase activity
AT01_3847	COG2226	methyltransferase
AT01_3848	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AT01_385	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AT01_3851	COG0556	nucleotide-excision repair
AT01_3852	COG4628	conserved protein (DUF2132)
AT01_3857	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AT01_3858	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AT01_386	COG2205	protein histidine kinase activity
AT01_3860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AT01_3861	COG0314	molybdopterin synthase activity
AT01_3862	COG0670	Belongs to the BI1 family
AT01_3863	COG0842	Transport permease protein
AT01_3864	COG0842	Transport permease protein
AT01_3865	COG1131	(ABC) transporter
AT01_3866	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT01_3867	COG1309	transcriptional regulator
AT01_3868	COG0513	Belongs to the DEAD box helicase family
AT01_3869	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AT01_387	COG0745	RESPONSE REGULATOR receiver
AT01_3873	COG1686	Belongs to the peptidase S11 family
AT01_3874	COG0277	FAD linked oxidase domain protein
AT01_3875	COG1403	HNH endonuclease
AT01_3877	COG2261	transglycosylase associated protein
AT01_3879	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AT01_3882	COG4807	Protein conserved in bacteria
AT01_3883	COG2897	thiosulfate sulfurtransferase activity
AT01_3886	COG1732	Glycine betaine
AT01_3888	COG1174	glycine betaine transport
AT01_3889	COG1125	glycine betaine transport
AT01_389	COG0531	amino acid
AT01_3890	COG1174	glycine betaine transport
AT01_3891	COG1982	Orn Lys Arg decarboxylase major
AT01_3893	COG0697	spore germination
AT01_3896	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AT01_3897	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AT01_3898	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AT01_3899	COG1126	abc transporter atp-binding protein
AT01_39	COG1349	DNA-binding transcription factor activity
AT01_3900	COG0765	amino acid transport
AT01_3901	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AT01_3902	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AT01_3903	COG0783	Belongs to the Dps family
AT01_3904	COG4106	trans-aconitate 2-methyltransferase activity
AT01_3907	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AT01_391	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AT01_3914	COG0488	(ABC) transporter
AT01_3915	COG3397	chitin binding
AT01_3916	COG3328	transposase activity
AT01_3918	COG0303	'Molybdopterin
AT01_392	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AT01_3920	COG0477	Major facilitator Superfamily
AT01_3922	COG1136	(ABC) transporter
AT01_3922	COG0577	efflux transmembrane transporter activity
AT01_3925	COG2801	Transposase and inactivated derivatives
AT01_3926	COG2963	transposase activity
AT01_393	COG0589	response to stress
AT01_3931	COG0583	DNA-binding transcription factor activity
AT01_3932	COG0477	Major facilitator Superfamily
AT01_3933	COG0302	gtp cyclohydrolase
AT01_3934	COG2311	Membrane
AT01_3935	COG1609	Transcriptional regulator
AT01_3939	COG3604	Transcriptional regulator
AT01_394	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AT01_3940	COG3383	formate dehydrogenase (NAD+) activity
AT01_3941	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AT01_3942	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AT01_3944	COG3260	NADH ubiquinone oxidoreductase 20
AT01_3945	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AT01_3946	COG3261	NADH dehydrogenase
AT01_3946	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AT01_3947	COG0651	ATP synthesis coupled electron transport
AT01_3948	COG4237	Hydrogenase 4 membrane
AT01_3949	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AT01_395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AT01_3950	COG0650	Formate hydrogenlyase subunit 4
AT01_3951	COG0651	ATP synthesis coupled electron transport
AT01_3952	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AT01_3953	COG0375	protein maturation
AT01_3954	COG0298	carbon dioxide binding
AT01_3955	COG2949	membrane
AT01_3956	COG0281	malic enzyme
AT01_3958	COG1346	cytolysis
AT01_3959	COG1380	Effector of murein hydrolase LrgA
AT01_3960	COG2814	Major facilitator Superfamily
AT01_3964	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AT01_3964	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AT01_3965	COG0489	protein tyrosine kinase activity
AT01_3966	COG0572	uridine kinase
AT01_3968	COG2982	Protein involved in outer membrane biogenesis
AT01_3969	COG3069	C4-dicarboxylate transmembrane transporter activity
AT01_397	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AT01_3970	COG1253	flavin adenine dinucleotide binding
AT01_3980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AT01_3983	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AT01_3987	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AT01_3988	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AT01_3989	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AT01_3990	COG0140	phosphoribosyl-ATP diphosphatase activity
AT01_3990	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AT01_3991	COG0107	imidazoleglycerol-phosphate synthase activity
AT01_3992	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AT01_3993	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AT01_3994	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AT01_3994	COG0131	Imidazoleglycerol-phosphate dehydratase
AT01_3995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AT01_3997	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AT01_3998	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AT01_3999	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_40	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AT01_400	COG1011	Hydrolase
AT01_4000	COG1129	ABC transporter
AT01_4001	COG0371	Dehydrogenase
AT01_4003	COG0531	amino acid
AT01_4004	COG2925	Exonuclease
AT01_4005	COG3320	Male sterility
AT01_4005	COG1022	Amp-dependent synthetase and ligase
AT01_4006	COG1289	transmembrane transporter activity
AT01_4009	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_4011	COG1879	ABC-type sugar transport system periplasmic component
AT01_4014	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AT01_4015	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AT01_4015	COG1648	precorrin-2 dehydrogenase activity
AT01_4016	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AT01_4018	COG4810	utilization protein
AT01_402	COG0440	acetolactate synthase activity
AT01_4020	COG4656	Part of a membrane complex involved in electron transport
AT01_4022	COG1012	belongs to the aldehyde dehydrogenase family
AT01_4028	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AT01_403	COG0028	Belongs to the TPP enzyme family
AT01_4036	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AT01_4041	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AT01_4043	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AT01_4044	COG2241	protein methyltransferase activity
AT01_4046	COG2875	Belongs to the precorrin methyltransferase family
AT01_4056	COG1492	cobalamin metabolic process
AT01_4060	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AT01_4061	COG2211	Major facilitator Superfamily
AT01_4073	COG3121	Chaperone
AT01_4074	COG3188	usher protein
AT01_4083	COG3501	Rhs element vgr protein
AT01_4087	COG0137	argininosuccinate synthase activity
AT01_4088	COG0534	Mate efflux family protein
AT01_409	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AT01_410	COG0583	DNA-binding transcription factor activity
AT01_414	COG3727	T/G mismatch-specific endonuclease activity
AT01_418	COG0625	glutathione transferase activity
AT01_422	COG3338	carbonate dehydratase activity
AT01_425	COG4221	oxidoreductase activity
AT01_427	COG1742	UPF0060 membrane protein
AT01_431	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AT01_432	COG1940	carbohydrate kinase activity
AT01_433	COG0583	DNA-binding transcription factor activity
AT01_434	COG2814	Major facilitator Superfamily
AT01_438	COG0114	fumarate hydratase activity
AT01_439	COG1482	cell wall glycoprotein biosynthetic process
AT01_440	COG5339	Protein conserved in bacteria
AT01_442	COG1609	Transcriptional regulator
AT01_443	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AT01_443	COG1263	PTS System
AT01_444	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AT01_445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AT01_446	COG0385	Bile acid
AT01_447	COG0673	inositol 2-dehydrogenase activity
AT01_449	COG1172	Belongs to the binding-protein-dependent transport system permease family
AT01_45	COG1501	Belongs to the glycosyl hydrolase 31 family
AT01_451	COG1879	ABC-type sugar transport system periplasmic component
AT01_454	COG2723	6-phospho-beta-galactosidase activity
AT01_455	COG2274	protein secretion by the type I secretion system
AT01_457	COG2274	protein secretion by the type I secretion system
AT01_458	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AT01_46	COG2211	Major facilitator Superfamily
AT01_460	COG4657	Part of a membrane complex involved in electron transport
AT01_463	COG3708	Transcriptional regulator
AT01_463	COG2207	Transcriptional regulator
AT01_465	COG4659	FMN binding
AT01_467	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AT01_468	COG0243	molybdopterin cofactor binding
AT01_469	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AT01_470	COG1966	Carbon starvation protein
AT01_471	COG2879	small protein
AT01_472	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AT01_473	COG1349	DNA-binding transcription factor activity
AT01_477	COG0023	Translation Initiation Factor
AT01_478	COG0284	orotidine-5'-phosphate decarboxylase activity
AT01_48	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AT01_481	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AT01_482	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AT01_483	COG0671	phosphoesterase, PA-phosphatase related
AT01_484	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AT01_485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AT01_488	COG0583	DNA-binding transcription factor activity
AT01_489	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AT01_491	COG0616	signal peptide processing
AT01_492	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_494	COG1187	pseudouridine synthase activity
AT01_495	COG0009	L-threonylcarbamoyladenylate synthase
AT01_496	COG0613	PHP domain protein
AT01_498	COG0512	Glutamine amidotransferase of anthranilate synthase
AT01_50	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AT01_500	COG0134	indole-3-glycerol-phosphate synthase activity
AT01_500	COG0135	phosphoribosylanthranilate isomerase activity
AT01_501	COG0133	tryptophan synthase activity
AT01_504	COG3047	cAMP biosynthetic process
AT01_507	COG2917	probably involved in intracellular septation
AT01_508	COG1607	acyl-coa hydrolase
AT01_509	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AT01_510	COG2350	Protein conserved in bacteria
AT01_512	COG2200	EAL domain
AT01_515	COG4608	Belongs to the ABC transporter superfamily
AT01_516	COG0444	Belongs to the ABC transporter superfamily
AT01_517	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AT01_521	COG2095	MarC family integral membrane protein
AT01_522	COG1454	alcohol dehydrogenase
AT01_522	COG1012	belongs to the aldehyde dehydrogenase family
AT01_523	COG1435	thymidine kinase activity
AT01_526	COG0745	RESPONSE REGULATOR receiver
AT01_527	COG1752	Esterase of the alpha-beta hydrolase superfamily
AT01_529	COG3012	SEC-C Motif Domain Protein
AT01_530	COG0788	formyltetrahydrofolate deformylase activity
AT01_533	COG0583	DNA-binding transcription factor activity
AT01_534	COG0708	Exodeoxyribonuclease III
AT01_535	COG0494	nUDIX hydrolase
AT01_537	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AT01_539	COG0778	Nitroreductase
AT01_540	COG0616	signal peptide processing
AT01_541	COG0252	asparaginase activity
AT01_542	COG1335	isochorismatase
AT01_543	COG3139	Protein of unknown function (DUF1315)
AT01_547	COG3713	MltA-interacting MipA family protein
AT01_548	COG2766	serine protein kinase
AT01_549	COG2718	Belongs to the UPF0229 family
AT01_551	COG2199	diguanylate cyclase activity
AT01_551	COG2200	EAL domain
AT01_551	COG2202	Pas domain
AT01_552	COG2814	Major facilitator Superfamily
AT01_553	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AT01_554	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AT01_555	COG2719	SpoVR family
AT01_556	COG2186	Transcriptional regulator
AT01_557	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AT01_558	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AT01_56	COG0604	alcohol dehydrogenase
AT01_56	COG3321	synthase
AT01_56	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_561	COG2983	Belongs to the UPF0260 family
AT01_562	COG0179	Fumarylacetoacetate (FAA) hydrolase
AT01_563	COG2951	lytic endotransglycosylase activity
AT01_566	COG0850	regulation of cytokinetic process
AT01_567	COG2894	cell division
AT01_568	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AT01_569	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AT01_570	COG0318	PFAM AMP-dependent synthetase and ligase
AT01_571	COG3065	identical protein binding
AT01_573	COG1199	ATP-dependent helicase activity
AT01_574	COG0251	oxidation-reduction process
AT01_575	COG2076	Multidrug Resistance protein
AT01_576	COG2076	Multidrug Resistance protein
AT01_577	COG0800	Aldolase
AT01_578	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AT01_579	COG1737	Transcriptional regulator
AT01_58	COG1278	Cold shock
AT01_580	COG0469	pyruvate kinase activity
AT01_581	COG1560	Kdo2-lipid A biosynthetic process
AT01_582	COG0739	heme binding
AT01_583	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AT01_584	COG1121	(ABC) transporter
AT01_585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AT01_586	COG3104	oligopeptide transport
AT01_587	COG2255	four-way junction helicase activity
AT01_588	COG0632	four-way junction helicase activity
AT01_590	COG0217	transcriptional regulatory protein
AT01_591	COG0494	nUDIX hydrolase
AT01_592	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AT01_593	COG1335	isochorismatase
AT01_594	COG1801	Protein of unknown function DUF72
AT01_595	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AT01_598	COG3142	Participates in the control of copper homeostasis
AT01_599	COG3102	Protein conserved in bacteria
AT01_6	COG3121	Chaperone
AT01_60	COG0840	transmembrane signaling receptor activity
AT01_602	COG0673	inositol 2-dehydrogenase activity
AT01_604	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AT01_605	COG0477	Major facilitator Superfamily
AT01_607	COG3381	protein complex oligomerization
AT01_609	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AT01_61	COG1285	pathogenesis
AT01_613	COG3706	GGDEF domain
AT01_615	COG0659	secondary active sulfate transmembrane transporter activity
AT01_616	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AT01_617	COG2912	Transglutaminase-like superfamily
AT01_618	COG3094	Invasion gene expression up-regulator, SirB
AT01_619	COG2890	protein-(glutamine-N5) methyltransferase activity
AT01_620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AT01_621	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AT01_622	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AT01_624	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AT01_626	COG0193	aminoacyl-tRNA hydrolase activity
AT01_628	COG0012	GTP binding
AT01_629	COG1393	Belongs to the ArsC family
AT01_63	COG2130	NADP-dependent
AT01_630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AT01_632	COG4942	peptidase
AT01_635	COG4211	Belongs to the binding-protein-dependent transport system permease family
AT01_636	COG1129	ABC transporter
AT01_64	COG0589	response to stress
AT01_641	COG1228	amidohydrolase
AT01_645	COG3724	N-succinylarginine dihydrolase activity
AT01_647	COG3138	arginine N-succinyltransferase
AT01_648	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AT01_649	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AT01_650	COG1271	oxidase subunit
AT01_651	COG1294	oxidase, subunit
AT01_653	COG3850	Histidine kinase
AT01_654	COG2814	Major facilitator Superfamily
AT01_656	COG0387	Pfam Sodium calcium exchanger
AT01_657	COG1702	phosphate starvation-inducible protein PhoH
AT01_660	COG3658	cytochrome
AT01_661	COG1215	transferase activity, transferring glycosyl groups
AT01_662	COG0726	polysaccharide deacetylase
AT01_662	COG1649	PFAM Uncharacterised BCR, COG1649
AT01_663	COG0457	Tetratricopeptide repeat
AT01_665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AT01_667	COG3615	Tellurite resistance protein tehB
AT01_667	COG0500	methyltransferase
AT01_669	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AT01_670	COG0577	efflux transmembrane transporter activity
AT01_670	COG1136	(ABC) transporter
AT01_672	COG1136	(ABC) transporter
AT01_672	COG0577	efflux transmembrane transporter activity
AT01_675	COG0672	)-iron permease
AT01_677	COG2066	Belongs to the glutaminase family
AT01_678	COG3328	transposase activity
AT01_679	COG3290	protein histidine kinase activity
AT01_680	COG4565	transcriptional regulatory protein
AT01_683	COG0346	lactoylglutathione lyase activity
AT01_684	COG0561	phosphatase activity
AT01_685	COG0745	RESPONSE REGULATOR receiver
AT01_685	COG3706	GGDEF domain
AT01_686	COG4999	Histidine kinase
AT01_686	COG3850	Histidine kinase
AT01_686	COG3437	response regulator, receiver
AT01_686	COG2205	protein histidine kinase activity
AT01_687	COG3250	beta-galactosidase activity
AT01_69	COG2198	Histidine kinase
AT01_69	COG0643	Histidine kinase
AT01_691	COG1215	transferase activity, transferring glycosyl groups
AT01_693	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AT01_697	COG0058	SHG alpha-glucan phosphorylase activity
AT01_70	COG0835	chemotaxis
AT01_703	COG3328	transposase activity
AT01_716	COG3157	Type VI secretion system effector, Hcp
AT01_72	COG0840	transmembrane signaling receptor activity
AT01_73	COG0840	transmembrane signaling receptor activity
AT01_74	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AT01_751	COG3566	protein conserved in bacteria
AT01_753	COG3567	Phage-associated protein, HI1409 family
AT01_755	COG3328	transposase activity
AT01_76	COG0745	RESPONSE REGULATOR receiver
AT01_760	COG1475	DNA binding
AT01_764	COG3772	lysozyme
AT01_77	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AT01_776	COG3756	Protein conserved in bacteria
AT01_78	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AT01_780	COG1396	sequence-specific DNA binding
AT01_788	COG0582	viral genome integration into host DNA
AT01_79	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AT01_790	COG1276	copper resistance
AT01_791	COG2372	response to copper ion
AT01_792	COG1528	Iron-storage protein
AT01_796	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AT01_797	COG1770	oligopeptidase
AT01_8	COG3188	usher protein
AT01_800	COG3141	response to X-ray
AT01_801	COG0513	Belongs to the DEAD box helicase family
AT01_802	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AT01_803	COG3140	Belongs to the UPF0181 family
AT01_805	COG0494	nUDIX hydrolase
AT01_806	COG1760	l-serine dehydratase
AT01_807	COG1253	flavin adenine dinucleotide binding
AT01_808	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AT01_808	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AT01_809	COG3715	PTS system
AT01_81	COG3418	PFAM FlgN family protein
AT01_810	COG3716	PTS system mannose fructose sorbose family IID component
AT01_812	COG1971	Probably functions as a manganese efflux pump
AT01_815	COG2226	methyltransferase
AT01_816	COG0768	penicillin binding
AT01_818	COG1278	Cold shock
AT01_82	COG2747	anti-sigma28 factor FlgM
AT01_820	COG1113	amino acid transport
AT01_827	COG2207	Transcriptional regulator
AT01_832	COG2801	Transposase and inactivated derivatives
AT01_833	COG2963	transposase activity
AT01_834	COG1132	(ABC) transporter
AT01_836	COG1733	regulation of RNA biosynthetic process
AT01_837	COG0702	epimerase
AT01_838	COG3240	lipase activity
AT01_84	COG1815	bacterial-type flagellum-dependent cell motility
AT01_845	COG0840	transmembrane signaling receptor activity
AT01_85	COG1558	bacterial-type flagellum-dependent cell motility
AT01_853	COG0538	isocitrate dehydrogenase activity
AT01_854	COG1187	pseudouridine synthase activity
AT01_856	COG0482	sulfurtransferase activity
AT01_857	COG2915	High frequency lysogenization protein hflD homolog
AT01_858	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AT01_86	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AT01_860	COG0745	RESPONSE REGULATOR receiver
AT01_862	COG2850	peptidyl-arginine hydroxylation
AT01_864	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AT01_865	COG1940	carbohydrate kinase activity
AT01_866	COG4591	ABC-type transport system involved in lipoprotein release permease component
AT01_868	COG4591	ABC-type transport system involved in lipoprotein release permease component
AT01_869	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AT01_87	COG1749	Flagellar hook protein flgE
AT01_870	COG3134	Outer membrane lipoprotein
AT01_871	COG1252	NADH dehydrogenase
AT01_872	COG3150	esterase
AT01_875	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AT01_876	COG5633	Lipoprotein
AT01_877	COG0537	adenosine 5'-monophosphoramidase activity
AT01_878	COG1263	PTS System
AT01_878	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AT01_879	COG0084	hydrolase, TatD family'
AT01_880	COG0470	DNA polymerase III
AT01_882	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AT01_883	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AT01_884	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AT01_886	COG1028	Short-chain dehydrogenase reductase Sdr
AT01_888	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AT01_889	COG0416	fatty acid biosynthetic process
AT01_89	COG4786	Flagellar basal body rod
AT01_890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AT01_891	COG1399	metal-binding, possibly nucleic acid-binding protein
AT01_893	COG0564	pseudouridine synthase activity
AT01_894	COG1530	ribonuclease E activity
AT01_894	COG1530	ribonuclease E activity
AT01_895	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AT01_896	COG0418	dihydroorotase activity
AT01_900	COG2197	response regulator
AT01_902	COG0628	permease
AT01_905	COG1560	Kdo2-lipid A biosynthetic process
AT01_906	COG2259	Doxx family
AT01_907	COG2814	Major facilitator Superfamily
AT01_908	COG3104	oligopeptide transport
AT01_909	COG0346	lactoylglutathione lyase activity
AT01_910	COG5645	(Lipo)protein
AT01_911	COG2943	transferase activity, transferring hexosyl groups
AT01_912	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AT01_917	COG2771	luxR family
AT01_918	COG3916	Acyl-homoserine-lactone synthase
AT01_920	COG0668	transmembrane transport
AT01_923	COG2920	part of a sulfur-relay system
AT01_924	COG1254	Belongs to the acylphosphatase family
AT01_926	COG3785	DNA binding
AT01_927	COG1832	CoA-binding protein
AT01_928	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AT01_929	COG1803	Methylglyoxal synthase
AT01_93	COG1256	bacterial-type flagellum assembly
AT01_930	COG0210	DNA helicase
AT01_931	COG3304	Inner membrane component domain
AT01_932	COG1289	transmembrane transporter activity
AT01_933	COG3070	regulator of competence-specific genes
AT01_934	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
AT01_935	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AT01_935	COG2885	chlorophyll binding
AT01_937	COG1067	ATP-dependent peptidase activity
AT01_938	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AT01_939	COG3009	Protein conserved in bacteria
AT01_94	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AT01_940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AT01_940	COG3008	intermembrane lipid transfer
AT01_941	COG2995	paraquat-inducible protein a
AT01_942	COG0488	(ABC) transporter
AT01_943	COG0116	Belongs to the methyltransferase superfamily
AT01_943	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AT01_944	COG0633	Ferredoxin
AT01_944	COG3217	Mosc domain protein beta barrel domain protein
AT01_946	COG0167	dihydroorotate dehydrogenase activity
AT01_947	COG0308	aminopeptidase N
AT01_948	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AT01_949	COG0017	Asparaginyl-tRNA synthetase
AT01_951	COG1448	Aminotransferase
AT01_952	COG2200	EAL domain
AT01_953	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AT01_954	COG3108	Peptidase M15
AT01_955	COG2989	Protein conserved in bacteria
AT01_956	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AT01_957	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AT01_958	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AT01_959	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AT01_960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AT01_962	COG3173	Aminoglycoside phosphotransferase
AT01_964	COG2835	tetraacyldisaccharide 4'-kinase activity
AT01_965	COG1278	Cold shock
AT01_966	COG1278	Cold shock
AT01_967	COG5383	Protein conserved in bacteria
AT01_968	COG1663	tetraacyldisaccharide 4'-kinase activity
AT01_970	COG0658	competence protein
AT01_970	COG2333	competence protein COMEC
AT01_972	COG0539	negative regulation of cytoplasmic translation
AT01_974	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AT01_975	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AT01_976	COG0252	asparaginase activity
AT01_977	COG1944	ATP diphosphatase activity
AT01_978	COG2116	formate transmembrane transporter activity
AT01_979	COG1882	Formate acetyltransferase
AT01_980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AT01_981	COG2814	Major facilitator Superfamily
AT01_982	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AT01_983	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AT01_984	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AT01_985	COG1674	ftsk spoiiie
AT01_985	COG3107	peptidoglycan biosynthetic process
AT01_987	COG0492	ferredoxin-NADP+ reductase activity
AT01_99	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AT01_990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AT01_991	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AT01_992	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AT01_993	COG0542	response to heat
AT01_994	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AT01_995	COG1278	Cold shock
AT01_997	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AT01_998	COG3593	DNA synthesis involved in DNA repair
AT01_999	COG2990	Protein conserved in bacteria