locus-tag	class	description
CH48_1	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
CH48_100	ENOG4106371	Methyltransferase
CH48_1000	ENOG4105D1Q	UPF0246 protein
CH48_1003	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CH48_1005	ENOG41065U4	response regulator
CH48_1006	ENOG4108RH0	Crea protein
CH48_1007	ENOG4105CVJ	phosphoglycerate mutase
CH48_1008	ENOG4105UEI	Transcriptional Regulator AraC Family
CH48_1009	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CH48_101	ENOG4107S90	membrAne
CH48_1010	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
CH48_1011	ENOG4107SC1	transglycosylase
CH48_1014	ENOG4108KHX	Diguanylate cyclase
CH48_1015	ENOG41090EK	ompa motb domain protein
CH48_1016	ENOG4105C5H	ABC transporter
CH48_1019	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
CH48_102	ENOG4107VR7	transferase activity, transferring phosphorus-containing groups
CH48_1020	ENOG4105CIS	alcohol dehydrogenase
CH48_1021	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CH48_1022	ENOG4105EAC	phosphoserine phosphatase
CH48_1023	ENOG41062Z9	Membrane
CH48_1024	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CH48_1025	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CH48_1026	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CH48_1027	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CH48_1028	ENOG4105D9N	nucleoside
CH48_1029	ENOG4105EYA	deoxyribonuclease
CH48_103	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CH48_1030	ENOG4108NRW	Phospholipase, patatin family
CH48_1032	ENOG4105K3G	Periplasmic Protein
CH48_1033	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CH48_1034	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CH48_1035	ENOG4108WPU	DNA polymerase III subunit psi
CH48_1036	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CH48_1037	ENOG4105CPC	Aldo Keto reductase
CH48_1038	ENOG4105CBN	LysR family transcriptional regulator
CH48_104	ENOG4105W49	UPF0434 protein
CH48_1041	ENOG4105YBH	Protein of unknown function (DUF1435)
CH48_1042	ENOG4105BZU	Histidine kinase
CH48_1043	ENOG4105GAV	receptor
CH48_1045	ENOG4105D7K	pfkb domain protein
CH48_1048	ENOG4108HKT	sucrose-6-phosphate hydrolase
CH48_1049	ENOG4105WBN	Transcriptional regulator (LacI family
CH48_105	ENOG4105VEQ	Cold shock protein
CH48_1050	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CH48_1058	ENOG4105VDH	Dihydroxyacetone kinase
CH48_1059	ENOG4108UTZ	Dihydroxyacetone kinase
CH48_106	ENOG4105VEQ	Cold shock protein
CH48_1060	ENOG4105CMT	Dihydroxyacetone kinase
CH48_1062	ENOG4105BZS	acriflavin resistance protein
CH48_1063	ENOG410624X	efflux transporter, rnd family, mfp subunit
CH48_1064	ENOG4105CEU	Arginine dihydrolase
CH48_1065	ENOG4105D5Q	Arginine ornithine antiporter
CH48_1067	ENOG4105DKP	glycosyl transferase, family 9
CH48_1068	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
CH48_1069	ENOG4105DKT	Transcriptional regulator
CH48_107	ENOG4105E32	cytoplasmic protein
CH48_1070	ENOG4105C2J	ABC transporter
CH48_1071	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
CH48_1072	ENOG4105F5R	ABC transporter
CH48_1073	ENOG4105D4B	ABC, transporter
CH48_1074	ENOG41061GT	Aldolase
CH48_1075	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
CH48_1077	ENOG4105RI1	glycoprotein receptor
CH48_1078	ENOG4105D5G	Transposase
CH48_108	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CH48_1085	ENOG4105VEV	-acetyltransferase
CH48_1096	ENOG4108K5H	permease YjgP YjgQ family protein
CH48_1097	ENOG4108M8S	permease YjgP YjgQ family protein
CH48_1098	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CH48_1099	ENOG4105MYG	DNA polymerase iii, chi subunit
CH48_11	ENOG4105EI2	Pseudouridine synthase
CH48_110	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
CH48_1101	ENOG4108MJ3	acetyltransferase
CH48_1103	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
CH48_1105	ENOG4105XEP	YhcH YjgK YiaL family protein
CH48_1107	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CH48_1108	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CH48_1109	ENOG4105C3U	ABC transporter
CH48_111	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CH48_1110	ENOG4108JQ7	(ABC) transporter
CH48_1111	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CH48_1112	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CH48_1115	ENOG4107RJJ	Transcriptional regulator
CH48_1116	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
CH48_1117	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
CH48_1118	ENOG4105EKV	Phosphonate metabolism protein
CH48_1119	ENOG4105FT8	Phosphonate metabolism
CH48_1120	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
CH48_1121	ENOG4105HRV	phosphonate c-p lyase system protein phnl
CH48_1122	ENOG4105FD8	phosphonate metabolism protein PhnM
CH48_1123	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
CH48_1124	ENOG4105K4T	epimerase
CH48_1125	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
CH48_1128	ENOG4108ZPB	UPF0306 protein
CH48_113	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CH48_1131	ENOG4105DRS	transport system, permease
CH48_1132	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CH48_1135	ENOG4105EY3	heparinase II III family protein
CH48_1136	ENOG4105CXN	decarboxylase
CH48_1137	ENOG4105D5Q	Arginine ornithine antiporter
CH48_1138	ENOG4108YYD	acetyltransferase
CH48_1139	ENOG41082IR	Excinuclease ABC C subunit domain protein
CH48_114	ENOG4105CAT	Cytidine monophosphate kinase
CH48_1140	ENOG4105XPQ	lipid carrier protein
CH48_1141	ENOG4105CFP	Peptidase U32
CH48_1142	ENOG4106RZ4	Peptidase U32
CH48_1143	ENOG4105CEM	UPF0597 protein
CH48_1144	ENOG4105C44	Serine transporter
CH48_1145	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CH48_1146	ENOG4105DEN	Luciferase family
CH48_1148	ENOG4105C1J	atp-dependent rna helicase
CH48_115	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CH48_1150	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CH48_1151	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CH48_1152	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CH48_1153	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CH48_1154	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CH48_1155	ENOG4105CHV	Transcription elongation factor NusA
CH48_1156	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CH48_116	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CH48_1160	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CH48_1161	ENOG4105EEI	dihydropteroate synthase
CH48_1162	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CH48_1163	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CH48_1164	ENOG4105HBR	Rna-binding protein
CH48_1165	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CH48_1166	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
CH48_1169	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CH48_117	ENOG4107VMU	Membrane
CH48_1170	ENOG4105QYV	Membrane
CH48_1171	ENOG4105K46	50S ribosomal protein l27
CH48_1172	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CH48_1173	ENOG4105EAH	synthase
CH48_1175	ENOG4105HVQ	Regulatory factor of maltose metabolism
CH48_1176	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CH48_1177	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CH48_1179	ENOG4105DFU	Cell wall formation (By similarity)
CH48_118	ENOG4105HDK	L-asparaginase
CH48_1182	ENOG4105DFU	Cell wall formation (By similarity)
CH48_1183	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH48_1184	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_1185	ENOG4105F0N	pyrophosphate phospho-hydrolase
CH48_1188	ENOG4108ZHD	aig2 family
CH48_119	ENOG4105DDY	UPF0142 protein ycaO
CH48_1192	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CH48_1193	ENOG4105C37	(CBS) domain
CH48_1194	ENOG41061GZ	Protein of unknown function (DUF1107)
CH48_1195	ENOG4108UUE	Transcriptional regulator
CH48_1196	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CH48_1197	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CH48_1199	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CH48_12	ENOG4107QQB	Ribonuclease E
CH48_120	ENOG4105TMB	Formate nitrite transporter
CH48_1200	ENOG4105FHY	Opacity-associated protein A
CH48_1202	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CH48_1203	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CH48_1204	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CH48_1206	ENOG4108MXZ	Esterase
CH48_1207	ENOG4105WSB	biofilm stress and motility protein A
CH48_1208	ENOG4105CSU	acyl-Coa dehydrogenase
CH48_1209	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CH48_121	ENOG4105C6N	Formate acetyltransferase
CH48_1210	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CH48_1211	ENOG4105KPV	Transcriptional regulator
CH48_1212	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CH48_1214	ENOG4105EPW	hflc protein
CH48_1215	ENOG4107QJR	hflk protein
CH48_1216	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CH48_1217	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CH48_1218	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CH48_1219	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CH48_122	ENOG4105F1A	Pyruvate formate-lyase
CH48_1220	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CH48_1221	ENOG4105K8N	protein family UPF0079, ATPase
CH48_1222	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CH48_1223	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CH48_1226	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CH48_1227	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CH48_1228	ENOG4105DJ4	phosphatidylserine decarboxylase
CH48_1229	ENOG4105EGS	Mechanosensitive ion channel
CH48_123	ENOG4108ISG	Major Facilitator
CH48_1230	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CH48_1233	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CH48_1234	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CH48_1236	ENOG4105KPY	Small multidrug resistance protein
CH48_1238	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CH48_1239	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CH48_1240	ENOG4108ZVF	(LipO)protein
CH48_1241	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CH48_1242	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CH48_1245	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CH48_1247	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CH48_1248	ENOG4105BZW	Glycerate kinase
CH48_1249	ENOG4108SIC	Transcriptional regulator
CH48_125	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CH48_1251	ENOG4105C6N	Formate acetyltransferase
CH48_1252	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CH48_1253	ENOG4108MST	Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity)
CH48_1254	ENOG4105C7B	Threonine dehydratase
CH48_1255	ENOG4105D4P	Coproporphyrinogen iii oxidase
CH48_1256	ENOG41090JE	Utilization Protein
CH48_1258	ENOG4107F3C	Hemin uptake protein
CH48_1259	ENOG4107ENK	receptor
CH48_126	ENOG4105D1H	recombination factor protein RarA
CH48_1260	ENOG4106QJH	hemin transport protein
CH48_1261	ENOG4107R4I	Periplasmic binding protein
CH48_1262	ENOG4105EHG	Permease protein
CH48_1263	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CH48_1264	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CH48_1266	ENOG4105E0K	tonB-dependent siderophore receptor
CH48_1267	ENOG4105EGS	Mechanosensitive ion channel
CH48_1268	ENOG4105VTW	prevent-host-death family
CH48_1269	ENOG4107RAN	Peptidase, M16
CH48_127	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CH48_1270	ENOG4105CQ0	ABC transporter
CH48_1271	ENOG4105PE1	Receptor
CH48_1272	ENOG4108S3W	Anti-feci sigma factor, fecr
CH48_1275	ENOG4105KSU	Redox protein
CH48_1276	ENOG41066VF	YeeE YedE family protein
CH48_1277	ENOG4108IUF	type iii secretion
CH48_1278	ENOG4108TN6	type iii secretion
CH48_1279	ENOG41083GP	type iii secretion
CH48_128	ENOG4105CNU	cell division protein FtsK
CH48_1280	ENOG4108HHI	Type III secretion system protein
CH48_1281	ENOG41063Q7	Type III secretion system protein
CH48_1284	ENOG4108JIR	Flagellum-specific ATP synthase
CH48_1286	ENOG4106H1D	secretion system apparatus protein
CH48_1287	ENOG4105UQF	type iii secretion
CH48_129	ENOG4105EW9	transcriptional regulator AsnC family
CH48_1299	ENOG4108SZ7	secretion system effector
CH48_13	ENOG41067V3	Antibiotic biosynthesis monooxygenase
CH48_1308	ENOG4105BZU	Histidine kinase
CH48_1309	ENOG4105WH1	Two component transcriptional regulator luxr family
CH48_131	ENOG4105C3M	thioredoxin reductase
CH48_1310	ENOG4105CK2	sodium dicarboxylate symporter
CH48_1311	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CH48_1312	ENOG41062QD	Membrane
CH48_1313	ENOG4107QN1	sodium solute
CH48_132	ENOG4108JJ9	ABC, transporter
CH48_1323	ENOG4108Z0R	Transferase
CH48_1324	ENOG4105E2X	shikimate dehydrogenase
CH48_1325	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CH48_1326	ENOG4108WI1	Dna topoisomerase
CH48_1328	ENOG4105C79	DNA protecting protein DprA
CH48_1329	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CH48_133	ENOG4108JJ8	(ABC) transporter
CH48_1330	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CH48_1331	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CH48_1332	ENOG4105C1A	potassium transporter peripheral membrane
CH48_1333	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CH48_1336	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
CH48_1337	ENOG4105W1Y	Transcriptional regulator
CH48_1338	ENOG4105VTS	DnaJ-like, subfamily C
CH48_1339	ENOG4108ZT0	50S ribosomal protein l17
CH48_134	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CH48_1340	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CH48_1341	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CH48_1342	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CH48_1343	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CH48_1344	ENOG41067V7	50S ribosomal protein L36
CH48_1345	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CH48_1346	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CH48_1347	ENOG4105VPB	50S ribosomal protein L30
CH48_1348	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CH48_1349	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CH48_135	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CH48_1350	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CH48_1352	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CH48_1353	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CH48_1354	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CH48_1356	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CH48_1357	ENOG41083MP	50s ribosomal protein l29
CH48_1358	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CH48_1359	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CH48_136	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CH48_1360	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CH48_1361	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CH48_1362	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CH48_1363	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CH48_1364	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CH48_1365	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CH48_137	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CH48_1370	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CH48_1372	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CH48_1374	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CH48_1375	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CH48_1376	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
CH48_1377	ENOG4105WWK	YheO domain protein
CH48_1378	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CH48_1380	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CH48_1381	ENOG4105VKU	nucleicacid-binding protein
CH48_1383	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CH48_1384	ENOG4105C5H	ABC transporter
CH48_1385	ENOG4105K64	Glycosyl transferase, family 2
CH48_1387	ENOG4105E2B	Taurine dioxygenase
CH48_1388	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CH48_139	ENOG4105VEQ	Cold shock protein
CH48_1390	ENOG4106FTQ	Taurine ABC transporter, periplasmic
CH48_1391	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CH48_1393	ENOG4105DNZ	Alpha Beta Hydrolase
CH48_1394	ENOG4105YP7	UPF0270 protein
CH48_1395	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CH48_1396	ENOG4108UKZ	OsmC family
CH48_1398	ENOG410613R	integral membrane protein, YccS YhfK family
CH48_1399	ENOG4105C8Y	Acetylornithine aminotransferase
CH48_14	ENOG4105EKE	dihydroorotase
CH48_1401	ENOG4105D7A	ATP-binding protein
CH48_1402	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CH48_1404	ENOG4105F8D	glycoside hydrolase family 4
CH48_1405	ENOG41060NJ	transcriptional regulator
CH48_1406	ENOG4106DTQ	Protein TsgA homolog
CH48_1407	ENOG4105DZC	cytosine deaminase
CH48_1408	ENOG4107QZF	nitrite reductase NADPH large subunit
CH48_1409	ENOG4105WZK	nitrite reductase NADPH small subunit
CH48_141	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CH48_1410	ENOG4107V9H	nitrite transporter
CH48_1411	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CH48_1412	ENOG4105C31	Tryptophanyl-tRNA synthetase
CH48_1414	ENOG4105DJV	ribulose-phosphate 3-epimerase
CH48_1418	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CH48_1419	ENOG4105E4G	Type IV pilus
CH48_142	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
CH48_1424	ENOG4108JQC	penicillin-binding protein 1A
CH48_1425	ENOG4107RK2	ADP-ribose diphosphatase NudE
CH48_1426	ENOG4105DQY	intracellular growth attenuator
CH48_1427	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
CH48_1428	ENOG4105VEJ	Heat shock protein
CH48_143	ENOG4108MJ5	VirK protein
CH48_1430	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CH48_1432	ENOG4105E0F	Histidine kinase
CH48_1433	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CH48_1434	ENOG4108RRZ	Transcription elongation factor GreB
CH48_1439	ENOG4105BZM	domain protein
CH48_144	ENOG4105DWU	Membrane
CH48_1440	ENOG4105XFK	Ferrous iron transport protein A
CH48_1441	ENOG4105CE1	Ferrous iron transport protein b
CH48_1442	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
CH48_1443	ENOG4105RID	UPF0379 protein yhcN
CH48_1444	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CH48_1445	ENOG4105MJ2	Competence protein
CH48_1446	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CH48_1449	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
CH48_145	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CH48_1450	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CH48_1452	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CH48_1453	ENOG41061ZR	Transcriptional regulator
CH48_1456	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
CH48_1457	ENOG4105E98	transcriptional regulator DeoR family
CH48_1459	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CH48_146	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CH48_1460	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CH48_1461	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CH48_1463	ENOG4108IUM	Glycogen debranching enzyme
CH48_1464	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CH48_1466	ENOG4108HRK	Histidine kinase
CH48_1468	ENOG4105C7K	acetolactate synthase
CH48_1469	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CH48_147	ENOG4105C7K	acetolactate synthase
CH48_1470	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CH48_1471	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CH48_1472	ENOG4105C6Z	Gluconate
CH48_1473	ENOG4105DIQ	Transcriptional regulator
CH48_1474	ENOG4105C2I	pirin domain protein
CH48_1475	ENOG4105WCN	acetyltransferase
CH48_1476	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
CH48_1477	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CH48_1479	ENOG4105D7K	pfkb domain protein
CH48_1481	ENOG4105DH8	myo-inositol catabolism
CH48_1482	ENOG4105C26	Dehydrogenase
CH48_1483	ENOG4105EQ0	Major Facilitator superfamily
CH48_1484	ENOG4105CR8	Transcriptional regulator
CH48_1486	ENOG4108HCJ	Hydrolase
CH48_1487	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CH48_1488	ENOG4107GFK	fumarate
CH48_1489	ENOG41090KR	LysR family transcriptional Regulator
CH48_149	ENOG4105C5W	Aldolase
CH48_1490	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CH48_1491	ENOG4105JZC	GHMP kinase
CH48_1492	ENOG4107WFU	Glutamate mutase subunit sigma
CH48_1494	ENOG4105DJI	Methylaspartate mutase, E subunit
CH48_1498	ENOG4105CK2	sodium dicarboxylate symporter
CH48_1499	ENOG4105CBX	hi0933 family
CH48_150	ENOG4105CGD	Nad-dependent epimerase dehydratase
CH48_1500	ENOG4105CJ3	phosphate transporter
CH48_1501	ENOG4108V6B	universal stress protein B
CH48_1502	ENOG4108M6U	Universal stress protein A
CH48_1505	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
CH48_1506	ENOG4105DGW	oligopeptidase A
CH48_1507	ENOG4105D6S	protein involved in catabolism of external DNA
CH48_1508	ENOG4105DC8	reductase
CH48_151	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CH48_1510	ENOG4107H3J	ribonuclease
CH48_1511	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
CH48_1512	ENOG41066T0	asmA family
CH48_1513	ENOG4105CMB	EAL domain-containing protein
CH48_1514	ENOG4105VSH	4-oxalocrotonate tautomerase
CH48_1516	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CH48_1517	ENOG4105CS0	peptidase
CH48_1518	ENOG4105CK2	sodium dicarboxylate symporter
CH48_152	ENOG41064MM	(LipO)protein
CH48_1521	ENOG4108PU9	oligogalacturonate-specific porin
CH48_1522	ENOG4105BZU	Histidine kinase
CH48_1525	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
CH48_1526	ENOG4107EEX	Cellulose synthase regulator protein
CH48_1527	ENOG4107QZ7	Cellulose synthase catalytic subunit
CH48_1528	ENOG4105UTS	cellulose synthase operon protein YhjQ
CH48_153	ENOG4105E5Z	arginine transporter ATP-binding subunit
CH48_1530	ENOG4105U74	cellulose biosynthesis protein BcsE
CH48_1531	ENOG410675P	Celllulose biosynthesis operon protein BcsF YhjT
CH48_1532	ENOG4105D1V	cellulose synthase operon protein YhjU
CH48_1533	ENOG4108JQ7	(ABC) transporter
CH48_1534	ENOG4105C3U	ABC transporter
CH48_1535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CH48_1536	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CH48_1537	ENOG4105DEF	Extracellular solute-binding protein, family 5
CH48_1539	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CH48_154	ENOG4106PMH	Extracellular solute-binding protein family 3
CH48_1540	ENOG4105DIJ	Phosphoethanolamine transferase
CH48_1541	ENOG4108KX4	response regulator
CH48_1542	ENOG4105BZU	Histidine kinase
CH48_1543	ENOG4105CXY	transporter
CH48_1546	ENOG4105D5K	Hemolysin activator protein
CH48_1547	ENOG4105CKT	filamentous hemagglutinin
CH48_1549	ENOG4105D5G	Transposase
CH48_155	ENOG4105GBT	ABC transporter
CH48_1550	ENOG4108X3P	Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures
CH48_1554	ENOG41060NJ	transcriptional regulator
CH48_1555	ENOG4105DKQ	ROK family
CH48_1556	ENOG4105VCP	PTS System
CH48_1557	ENOG4105CK1	PTS System
CH48_1558	ENOG4105VZJ	PTS System
CH48_1559	ENOG4105CK1	PTS System
CH48_156	ENOG4105DMR	ABC, transporter
CH48_1563	ENOG4105CS2	ec 3.2.1.21
CH48_1564	ENOG4105EIP	mannose-6-phosphate isomerase
CH48_1566	ENOG4105CW0	outer membrane usher protein
CH48_1568	ENOG4105CGP	Urocanate hydratase
CH48_1569	ENOG4105C84	Histidine ammonia-lyase
CH48_157	ENOG4106TNF	Periplasmic binding protein
CH48_1570	ENOG4105C85	amino acid
CH48_1576	ENOG4105ZTC	transcriptional activator, Ogr delta
CH48_1578	ENOG4105DFP	Integrase
CH48_158	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
CH48_1580	ENOG4105T16	Transcriptional regulator (AraC family)
CH48_1581	ENOG4107RNG	ABC transporter
CH48_1583	ENOG4105DFW	ABC transporter
CH48_1584	ENOG4105C93	Xylose Isomerase
CH48_1585	ENOG4105CMG	Carbohydrate kinase
CH48_1586	ENOG4108TTM	chaperone
CH48_1588	ENOG4105MEV	Acyl-transferase
CH48_159	ENOG4105RBQ	inner membrane protein ybjO
CH48_1591	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CH48_1592	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
CH48_1593	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
CH48_1594	ENOG4108MG3	formate dehydrogenase
CH48_1595	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CH48_1596	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CH48_1597	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CH48_1598	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CH48_1599	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CH48_16	ENOG4105PVA	Biofilm formation regulatory protein BssS
CH48_160	ENOG4105D38	putrescine abc transporter
CH48_1600	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_1601	ENOG4108RPX	mosc domain containing protein
CH48_1602	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
CH48_1604	ENOG4108YYI	Protein of unknown function (DUF2810)
CH48_1605	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CH48_1606	ENOG4105E61	Mannitol repressor protein
CH48_1608	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
CH48_1609	ENOG4105CTS	PTS system mannitol-specific
CH48_161	ENOG4105F38	ABC transporter, permease
CH48_1610	ENOG4106JH6	(LipO)protein
CH48_1611	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CH48_1612	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CH48_1613	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CH48_1614	ENOG4105HNP	-acetyltransferase
CH48_162	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CH48_1620	ENOG4105C5I	Dehydrogenase
CH48_1621	ENOG4107T9C	Alpha amylase catalytic region
CH48_1622	ENOG4105JKW	Valine--pyruvate aminotransferase
CH48_1623	ENOG4105D0C	transport protein
CH48_1627	ENOG4105R2A	(LipO)protein
CH48_1628	ENOG4105D99	atp gtp-binding protein
CH48_1629	ENOG4105C7B	Threonine dehydratase
CH48_163	ENOG4107RUE	extracellular solute-binding protein family 1
CH48_1631	ENOG410667J	hydrolase
CH48_1632	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CH48_1633	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CH48_1634	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CH48_1635	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CH48_1636	ENOG4105VG0	50S ribosomal protein l34
CH48_1637	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CH48_1639	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CH48_164	ENOG4108RMJ	sensory transduction regulator
CH48_1640	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CH48_1641	ENOG4105RKW	reductase (By
CH48_1644	ENOG4108UMI	ABC transporter, permease
CH48_1645	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_1646	ENOG4108YYH	Nadph-dependent fmn reductase
CH48_1647	ENOG4105BZU	Histidine kinase
CH48_1648	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CH48_165	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
CH48_1650	ENOG4105C7N	Xanthine uracil vitamin C permease
CH48_1651	ENOG4105DRP	amino acid AbC transporter
CH48_1652	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
CH48_1653	ENOG4105EAD	ABC transporter
CH48_1654	ENOG4106PMH	Extracellular solute-binding protein family 3
CH48_1658	ENOG4105E2Z	phosphate ABC transporter (Permease
CH48_1659	ENOG4105C8U	phosphate abc transporter
CH48_166	ENOG41090BQ	Glutaredoxin
CH48_1660	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CH48_1662	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CH48_1663	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CH48_1664	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CH48_1665	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CH48_1666	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CH48_1667	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CH48_1668	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CH48_1669	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CH48_167	ENOG4105D0C	transport protein
CH48_1670	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CH48_1671	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CH48_1672	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
CH48_1673	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CH48_1674	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CH48_1675	ENOG4105QTB	Flavodoxin
CH48_1676	ENOG4108VVK	transcriptional Regulator, AsnC
CH48_1677	ENOG4105CU9	asparagine synthetase A
CH48_1679	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
CH48_1680	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
CH48_1682	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CH48_1684	ENOG4105CNN	ABC, transporter
CH48_1685	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CH48_1686	ENOG4108RVA	ribokinase
CH48_1688	ENOG4105ETE	Transcriptional regulator (LacI family
CH48_169	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
CH48_1690	ENOG4107EJG	GntR family transcriptional regulator
CH48_1698	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
CH48_170	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CH48_1700	ENOG4105PC1	Conserved Protein
CH48_1701	ENOG4105E27	serine threonine protein kinase
CH48_1702	ENOG4108Z33	Thiol disulfide Interchange Protein
CH48_1703	ENOG4105C2M	dna polymerase I
CH48_1704	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CH48_1705	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
CH48_1706	ENOG4105D4P	Coproporphyrinogen iii oxidase
CH48_1707	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CH48_1708	ENOG4105CUX	Signal transduction histidine kinase
CH48_171	ENOG4107FB0	transcriptional regulator DeoR family
CH48_1710	ENOG4105C5F	glutamine synthetase
CH48_1712	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
CH48_1713	ENOG4107S2Z	UPF0761 membrane protein
CH48_1714	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CH48_1715	ENOG4105SUU	thioesterase domain
CH48_1716	ENOG4105HVQ	Regulatory factor of maltose metabolism
CH48_1719	ENOG4105JV1	AsmA family
CH48_172	ENOG4105C44	Serine transporter
CH48_1721	ENOG4105C2W	permease
CH48_1722	ENOG4105D6U	Sodium Glutamate Symporter
CH48_1724	ENOG4105CB5	ATP-dependent DNA helicase recG
CH48_1725	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
CH48_1726	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CH48_1727	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CH48_173	ENOG4105EJQ	L-serine dehydratase
CH48_1731	ENOG4105EN6	Membrane
CH48_1733	ENOG4105D9N	nucleoside
CH48_1734	ENOG4105E39	Enoyl-CoA hydratase
CH48_1735	ENOG4105BZU	Histidine kinase
CH48_1738	ENOG4105DSJ	YicC domain protein
CH48_1739	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CH48_1740	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CH48_1741	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CH48_1742	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CH48_1743	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CH48_1744	ENOG4105W5Q	DNA repair protein (RadC
CH48_1745	ENOG4105KDC	50s ribosomal protein l28
CH48_1746	ENOG4105W0E	50S ribosomal protein L33
CH48_1747	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CH48_1748	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CH48_1750	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CH48_1751	ENOG4105D16	lipopolysaccharide heptosyltransferase i
CH48_1752	ENOG4105XA0	heptosyltransferase ii
CH48_1753	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CH48_1754	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CH48_1755	ENOG4105CPQ	Dehydrogenase
CH48_1758	ENOG4105PXI	polysaccharide deacetylase
CH48_1759	ENOG41063SB	peptidase
CH48_176	ENOG4105DZ1	carboxypeptidase
CH48_1760	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CH48_1761	ENOG4107YZP	Rhodanese domain protein
CH48_1762	ENOG4105VW4	glutaredoxin 3
CH48_1763	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CH48_1764	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CH48_1765	ENOG4105D7W	serine acetyltransferase
CH48_1766	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CH48_1767	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CH48_1768	ENOG4105E0F	Histidine kinase
CH48_1769	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CH48_1770	ENOG4105FMW	periplasmic
CH48_1771	ENOG41076HS	cation diffusion facilitator family transporter
CH48_1773	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CH48_1775	ENOG4105CP7	Triose-phosphate isomerase
CH48_1776	ENOG4105EBK	exported protein
CH48_1777	ENOG4108VTS	Membrane
CH48_1778	ENOG4105DP0	ferredoxin-NADP reductase
CH48_178	ENOG4105C28	cystathionine
CH48_1781	ENOG4105E5M	Multidrug resistance protein D
CH48_1782	ENOG4105CBT	Fructose-1,6-bisphosphatase
CH48_1783	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CH48_1784	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CH48_1785	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
CH48_1786	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CH48_1787	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CH48_1788	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CH48_1789	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CH48_179	ENOG4108UMI	ABC transporter, permease
CH48_1790	ENOG41063M6	Cell Division Protein
CH48_1791	ENOG4105ETE	Transcriptional regulator (LacI family
CH48_1792	ENOG4105C25	Primosomal protein n'
CH48_1793	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CH48_1794	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
CH48_1795	ENOG4105C28	cystathionine
CH48_1796	ENOG4105CFH	Aspartokinase
CH48_1797	ENOG4105SYT	Methylenetetrahydrofolate reductase
CH48_1798	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CH48_1800	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CH48_1801	ENOG4105CAS	nag kinase
CH48_1802	ENOG4105CH7	arginosuccinase
CH48_1803	ENOG4105X58	receptor
CH48_1808	ENOG4107QZV	Type I secretion membrane fusion protein
CH48_181	ENOG4105D01	(LipO)protein
CH48_1810	ENOG4107QN2	dihydrolipoyl dehydrogenase
CH48_1811	ENOG4105EHV	domain protein
CH48_1812	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
CH48_1813	ENOG4105C5Q	Transcriptional regulator
CH48_1814	ENOG4105EJ2	Transcriptional regulator
CH48_1815	ENOG4108Y73	Membrane
CH48_1817	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CH48_1819	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CH48_1828	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
CH48_1829	ENOG4105C2J	ABC transporter
CH48_1830	ENOG4107R9N	ABC transporter
CH48_1831	ENOG4105CVI	Transcriptional regulator
CH48_1832	ENOG41062B0	ABC transporter, permease
CH48_1833	ENOG4108WFC	UPF0438 protein yifE
CH48_1834	ENOG4105C0P	Mg chelatase subunit ChlI
CH48_1836	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
CH48_1837	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CH48_1838	ENOG4105C01	Dihydroxy-acid dehydratase
CH48_1839	ENOG4105C7B	Threonine dehydratase
CH48_1842	ENOG4105EMY	transcriptional regulator
CH48_1844	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CH48_1845	ENOG4108MA7	Inherit from COG: YD repeat protein
CH48_1847	ENOG41060S4	immunity protein
CH48_1849	ENOG4108VEV	chaperone
CH48_185	ENOG4108TGY	Glutathione S-transferase
CH48_1851	ENOG4105CW0	outer membrane usher protein
CH48_1852	ENOG4105GQR	Chaperone
CH48_1854	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
CH48_1855	ENOG4105C4R	Atp-dependent dna helicase
CH48_1857	ENOG4105C9X	ppx gppa phosphatase
CH48_1859	ENOG4105K63	Thioredoxin
CH48_186	ENOG4105D05	Receptor
CH48_1862	ENOG4105ESV	Glycosyl transferase, family 4
CH48_1863	ENOG4105SFE	lipopolysaccharide biosynthesis protein
CH48_1864	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CH48_1865	ENOG4108IJ1	Dehydrogenase
CH48_1866	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CH48_1867	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CH48_1868	ENOG4108WJ1	acetyltransferase
CH48_1869	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CH48_1870	ENOG4105EGZ	biosynthesis protein
CH48_1871	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
CH48_1874	ENOG4105C85	amino acid
CH48_188	ENOG4105EHG	Permease protein
CH48_1881	ENOG410601J	HemY protein
CH48_1882	ENOG4105ECF	c-methyltransferase
CH48_1883	ENOG41076E6	Uroporphyrinogen-III Synthase
CH48_1884	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CH48_1886	ENOG4105XQ6	frataxin-like protein
CH48_1887	ENOG4105S7Z	(LipO)protein
CH48_1888	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CH48_1889	ENOG4105CT0	Protein of unknown function, DUF484
CH48_189	ENOG4108IQI	permease
CH48_1890	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CH48_1891	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
CH48_1892	ENOG4105C4R	Atp-dependent dna helicase
CH48_1894	ENOG4105EQN	UPF0261 protein
CH48_1896	ENOG4107QUT	magnesium and cobalt transport protein CorA
CH48_1897	ENOG4105FR1	rard protein
CH48_1898	ENOG4108VUY	thioesterase Superfamily protein
CH48_1899	ENOG4105HDD	phospholipase
CH48_19	ENOG4105DSF	transport protein
CH48_190	ENOG4105DUM	transcriptional regulator, lysR family
CH48_1900	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CH48_1901	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
CH48_1903	ENOG4108EUD	Lysophospholipase
CH48_1904	ENOG4105DQF	Hydrolase
CH48_1905	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CH48_1906	ENOG4105CXY	transporter
CH48_1907	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
CH48_1908	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
CH48_1909	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CH48_1910	ENOG4108W1V	Lipoprotein
CH48_1911	ENOG4105EX9	Membrane
CH48_1912	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CH48_1913	ENOG4105C59	p-type ATPase
CH48_1915	ENOG4107FS9	Membrane
CH48_1918	ENOG4105MG3	Membrane
CH48_1919	ENOG4106H78	methyltransferase
CH48_1920	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CH48_1921	ENOG4105CAK	Cell division ATP-binding protein ftsE
CH48_1922	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CH48_1926	ENOG4105U59	-acetyltransferase
CH48_1927	ENOG4105CP9	extracellular ligand-binding receptor
CH48_1928	ENOG4105C32	Amino acid ABC transporter (Permease)
CH48_1929	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CH48_1930	ENOG4105C0Z	ABC transporter
CH48_1931	ENOG4108IV0	ABC, transporter
CH48_1938	ENOG4105BZ7	extracellular solute-binding protein family 1
CH48_1939	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CH48_194	ENOG4105HMI	Membrane
CH48_1940	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
CH48_1941	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CH48_1942	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
CH48_1943	ENOG4105RK9	auxin efflux carrier
CH48_1944	ENOG4105DZ2	Transcriptional regulator
CH48_1945	ENOG4105EMK	carboxylate amino acid amine transporter
CH48_1946	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CH48_1947	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
CH48_1948	ENOG4108I5U	Uridine phosphorylase
CH48_195	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CH48_1952	ENOG4108KF1	Membrane
CH48_1953	ENOG4105CGY	Dna recombination protein
CH48_1954	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CH48_1955	ENOG4105JC1	sterol-binding domain protein
CH48_1956	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CH48_1957	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CH48_1958	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CH48_1959	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CH48_196	ENOG4108D1K	outer membrane usher protein
CH48_1961	ENOG4105D52	delta-aminolevulinic acid dehydratase
CH48_1962	ENOG4105MDZ	Transcriptional activator rfaH
CH48_1963	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CH48_1964	ENOG4107QK7	reductase
CH48_1965	ENOG4105CHU	acetyl-coa acetyltransferase
CH48_1966	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CH48_1968	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
CH48_1969	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CH48_197	ENOG4108UIF	Chaperone
CH48_1970	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CH48_1971	ENOG4108RR8	protoporphyrinogen oxidase
CH48_1978	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_1980	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CH48_1981	ENOG4105CS9	pantothenic acid kinase
CH48_1987	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CH48_1988	ENOG4105PM1	preprotein translocase subunit SecE
CH48_1989	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CH48_1990	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CH48_1991	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CH48_1992	ENOG4108VZM	50s ribosomal protein L10
CH48_1993	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CH48_1994	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CH48_1995	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CH48_1997	ENOG4105D41	biosynthesis protein thiH
CH48_1998	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CH48_1999	ENOG4105WHD	thiamine biosynthesis protein ThiS
CH48_2	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CH48_20	ENOG4105C72	UPF0176 protein
CH48_200	ENOG4108SGD	regulatory protein
CH48_2000	ENOG4105D06	uba thif-type nad fad binding protein
CH48_2002	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CH48_2003	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
CH48_2004	ENOG4105E09	nadh pyrophosphatase
CH48_2005	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CH48_2006	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
CH48_2007	ENOG4105R2J	Conserved Protein
CH48_2009	ENOG4108T8B	Protein of unknown function (DUF1481)
CH48_201	ENOG4105DM4	PTS System
CH48_2010	ENOG4105C12	Phosphoribosylglycinamide synthetase
CH48_2011	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CH48_202	ENOG4105DE4	1-phosphofructokinase
CH48_2020	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_2021	ENOG4105CVG	Homoserine O-transsuccinylase
CH48_2022	ENOG4107QP3	malate synthase g
CH48_2023	ENOG4108I9X	Isocitrate lyase
CH48_2024	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CH48_2025	ENOG41069M3	Transcriptional regulator
CH48_2026	ENOG4105C3R	Methionine synthase
CH48_2029	ENOG4105C09	Bile acid
CH48_203	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CH48_2030	ENOG4105CFH	Aspartokinase
CH48_2031	ENOG4107QP8	phosphohexose isomerase
CH48_2033	ENOG4105EG2	ABC transporter, permease
CH48_2034	ENOG4105D56	permease protein
CH48_2035	ENOG4107FKK	extracellular solute-binding protein family 1
CH48_2037	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CH48_2038	ENOG4107W52	maltose operon periplasmic protein
CH48_2040	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CH48_2041	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CH48_2042	ENOG4105E55	glycerol-3-phosphate acyltransferase
CH48_2043	ENOG41080IJ	Diacylglycerol kinase
CH48_2044	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CH48_2045	ENOG4105VDW	Csbd family
CH48_2046	ENOG4105MYN	Zinc uptake regulation protein
CH48_2047	ENOG4105EXC	Acyl-transferase
CH48_2048	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CH48_2049	ENOG4105P4Z	Phage shock protein G
CH48_205	ENOG4105CUW	cytochrome C-TYPE protein
CH48_2051	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CH48_2052	ENOG4105CDU	Replicative dna helicase
CH48_2053	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CH48_2054	ENOG4105CGF	Aromatic amino acid aminotransferase
CH48_2056	ENOG4105MSB	protein, conserved in bacteria
CH48_2057	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CH48_2058	ENOG4108UUM	single-stranded DNA-binding protein
CH48_2059	ENOG4105CAF	HipA N-terminal domain protein
CH48_206	ENOG4107QY8	reductase
CH48_2062	ENOG4105C7N	Xanthine uracil vitamin C permease
CH48_2063	ENOG4105EEQ	Na H antiporter
CH48_2064	ENOG4105CMU	LysR family (Transcriptional regulator
CH48_2067	ENOG4105CDA	abc transporter atp-binding protein
CH48_2068	ENOG4105DRP	amino acid AbC transporter
CH48_2069	ENOG4105EZ7	amino acid ABC transporter
CH48_2072	ENOG4105D1S	lipid A biosynthesis
CH48_2073	ENOG4107QPK	)-transporter
CH48_2074	ENOG4105VEQ	Cold shock protein
CH48_2075	ENOG4105VEQ	Cold shock protein
CH48_2076	ENOG4108XTF	Outer Membrane Lipoprotein
CH48_2077	ENOG4105BZU	Histidine kinase
CH48_2078	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CH48_2079	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CH48_2080	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CH48_2082	ENOG4108IA2	Sodium pantothenate symporter
CH48_2083	ENOG4105RG0	Membrane
CH48_2084	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CH48_2085	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CH48_2086	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CH48_2087	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CH48_2089	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CH48_209	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CH48_2091	ENOG41062P1	Diguanylate cyclase phosphodiesterase
CH48_2092	ENOG4105DFF	Rod shape-determining protein mreb
CH48_2093	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CH48_2094	ENOG4105VQ7	Rod shape-determining protein MreD
CH48_2096	ENOG4105C03	ribonuclease
CH48_2097	ENOG4105QD6	exported protein
CH48_2099	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CH48_210	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
CH48_211	ENOG4105DEI	Mannitol dehydrogenase
CH48_2114	ENOG4105CR8	Transcriptional regulator
CH48_2116	ENOG4105Y49	secretion protein, HlyD family
CH48_2117	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
CH48_212	ENOG4107YCY	Transcriptional regulator
CH48_2120	ENOG4105UNR	(Barnase) inhibitor
CH48_2121	ENOG4105N42	UPF0307 protein
CH48_2122	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CH48_2124	ENOG4108XVM	Cytochrome b(562)
CH48_2125	ENOG4105NXH	GreA GreB family elongation factor
CH48_2131	ENOG41069H0	dihydroorotase EC 3.5.2.3
CH48_2134	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CH48_2135	ENOG4105EMD	TRANSCRIPTIONal
CH48_2136	ENOG41084S7	Plasmid maintenance system antidote protein
CH48_2138	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CH48_214	ENOG4105CKI	cobalamin synthesis protein
CH48_2140	ENOG4105D4X	repressor
CH48_2141	ENOG4105C5Y	PTS System
CH48_2142	ENOG4105CG3	alpha amylase, catalytic region
CH48_2147	ENOG4105KME	endoribonuclease L-psp
CH48_2148	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CH48_2149	ENOG4105CXT	aspartate transcarbamylase
CH48_215	ENOG41076MN	Phosphoesterase, PA-phosphatase related
CH48_2151	ENOG41080Z8	PHOSPHOCARRIER protein
CH48_2152	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CH48_2153	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CH48_2154	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CH48_2155	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CH48_2156	ENOG4108IUZ	ABC transporter
CH48_2157	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CH48_2158	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
CH48_2159	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CH48_216	ENOG4107TT5	NLP P60 protein
CH48_2160	ENOG4105C2X	Arabinose 5-phosphate isomerase
CH48_2161	ENOG4105FEU	K -dependent Na -Ca exchanger
CH48_2162	ENOG4105DHJ	ABC, transporter
CH48_2163	ENOG4105CY3	ABC transporter, permease
CH48_2164	ENOG4107PE3	Mammalian cell entry related domain protein
CH48_2165	ENOG4105E3I	toluene tolerance
CH48_2166	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
CH48_2167	ENOG4105VFK	BolA family
CH48_2168	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CH48_2169	ENOG4105C0H	protease
CH48_217	ENOG4105CXC	rtn protein
CH48_2170	ENOG4105C0H	protease
CH48_2171	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
CH48_2172	ENOG4105D6Z	AFG1 family ATPase
CH48_2173	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CH48_2174	ENOG4108UJD	30S ribosomal protein S9
CH48_2175	ENOG4107MKT	Stringent starvation protein a
CH48_2176	ENOG4105KB2	stringent starvation protein b
CH48_2178	ENOG4105BZ8	glutamate synthase
CH48_2179	ENOG4105CBC	glutamate synthase
CH48_218	ENOG4105E43	Extracellular solute-binding protein, family 5
CH48_2180	ENOG4105N5T	Radical SAM Protein
CH48_2181	ENOG4105BZU	Histidine kinase
CH48_2182	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
CH48_2183	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CH48_2184	ENOG4105W4M	Transport-associated protein
CH48_2185	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CH48_2186	ENOG41082RQ	UPF0102 protein
CH48_2188	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CH48_219	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
CH48_2190	ENOG4108VEV	chaperone
CH48_2193	ENOG4105EQ2	LysR family Transcriptional regulator
CH48_2194	ENOG4107SET	aldo keto reductase
CH48_2195	ENOG4105DQ4	alcohol dehydrogenase
CH48_2196	ENOG4108CNN	domain protein
CH48_2197	ENOG4105CWB	LysR family transcriptional Regulator
CH48_2198	ENOG4105CHF	Glutathione S-transferase
CH48_2199	ENOG4108VBZ	doxx family
CH48_22	ENOG4105DB1	molybdopterin oxidoreductase
CH48_220	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CH48_2200	ENOG4105YJD	
CH48_2201	ENOG41090KG	Inner membrane protein YqjE
CH48_2202	ENOG4105NE1	Conserved Protein
CH48_2205	ENOG4106W5V	Membrane
CH48_2208	ENOG4105DPW	Major facilitator superfamily MFS_1
CH48_2209	ENOG4105D2H	Uronic isomerase
CH48_221	ENOG4108JQ5	ABC transporter
CH48_2210	ENOG4107QZW	Altronate oxidoreductase
CH48_2211	ENOG4105CTX	dehydratase
CH48_2212	ENOG4105P66	Membrane
CH48_2213	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CH48_2214	ENOG4105DU1	integral membrane protein, terc
CH48_2215	ENOG4105EE0	oxidoreductase
CH48_2216	ENOG4108VKG	metal-dependent hydrolase
CH48_2219	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CH48_222	ENOG4105HG6	
CH48_2221	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CH48_2222	ENOG4108594	Permease of the drug metabolite transporter
CH48_2223	ENOG4108YK4	Acid-resistance membrane protein
CH48_2225	ENOG4105CVK	Glutamate decarboxylase
CH48_2226	ENOG4105E5D	amino acid
CH48_2227	ENOG4105CSV	Glutaminase
CH48_2228	ENOG4105C5Y	PTS System
CH48_2229	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CH48_223	ENOG4105C2C	drug resistance transporter, Bcr CflA
CH48_2230	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
CH48_2231	ENOG4105D17	glycoside hydrolase, family 3 domain protein
CH48_2233	ENOG4105EHZ	conserved protein UCP016719
CH48_2236	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CH48_2237	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CH48_2238	ENOG4105VCC	30S ribosomal protein S21
CH48_2239	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CH48_224	ENOG4105I08	Pseudouridine synthase
CH48_2240	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CH48_2241	ENOG4107ZVW	dihydroneopterin aldolase
CH48_2242	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CH48_2243	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CH48_2244	ENOG4106MWK	domain protein
CH48_2245	ENOG4105I7R	Adenylate cyclase
CH48_2246	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CH48_2247	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CH48_2248	ENOG4105DVH	amino acid
CH48_2249	ENOG4105W0Z	cytoplasmic protein
CH48_225	ENOG4105CFI	type iii restriction protein res subunit
CH48_2250	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CH48_2251	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CH48_2252	ENOG4106032	Glutathionylspermidine synthase
CH48_2253	ENOG4105F1G	UPF0441 protein
CH48_2254	ENOG4105DFG	type I secretion outer membrane protein
CH48_2255	ENOG41087AY	ADP-Ribose pyrophosphatase
CH48_2256	ENOG4108SX3	cytoplasmic protein
CH48_2257	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CH48_2258	ENOG4105IPS	esterase
CH48_2259	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CH48_226	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CH48_2260	ENOG4105JQN	Transcriptional regulator
CH48_2261	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
CH48_2262	ENOG4105NF4	modulator of drug activity
CH48_2263	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CH48_2264	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
CH48_2265	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
CH48_2267	ENOG4105CV8	reductase
CH48_2268	ENOG4108I6A	alcohol dehydrogenase
CH48_2269	ENOG4105CF7	AraC family transcriptional regulator
CH48_227	ENOG4106V8H	Nucleoid-associated protein
CH48_2270	ENOG4108K81	inner membrane protein YghB
CH48_2271	ENOG4105C28	cystathionine
CH48_2272	ENOG4105CWK	Biopolymer transport protein, ExbB
CH48_2273	ENOG4108ZZF	transport protein (ExbD)
CH48_228	ENOG4105PAN	UPF0352 protein
CH48_2288	ENOG4105CF1	Alkylated DNA repair protein
CH48_2289	ENOG4108IJF	Heavy metal efflux pump, CzcA
CH48_229	ENOG4105E68	Sulfatase
CH48_2297	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CH48_2302	ENOG4105E0A	ABC, transporter
CH48_2303	ENOG4105TVJ	transport system, permease
CH48_2304	ENOG4105DQ5	transport system permease protein
CH48_2305	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
CH48_2306	ENOG4105CSP	Major Facilitator Superfamily
CH48_2307	ENOG4105EXW	epimerase dehydratase
CH48_2308	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_2311	ENOG4105D00	flagellar biosynthetic protein flhB
CH48_2312	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CH48_2313	ENOG4105VS8	Flagellar biosynthetic protein fliq
CH48_2314	ENOG4105CN7	Flagellar biosynthetic protein FliP
CH48_2315	ENOG4105DD5	Flagellar motor switch protein
CH48_2317	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CH48_2318	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CH48_2319	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CH48_2322	ENOG4108JIR	Flagellum-specific ATP synthase
CH48_2328	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CH48_2329	ENOG4108ZC9	flagellar basal-body rod protein flgc
CH48_233	ENOG4105D5G	Transposase
CH48_2330	ENOG4105W00	Flagellar hook capping protein
CH48_2331	ENOG4105BZE	flagellar hook protein, FlgE
CH48_2332	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CH48_2333	ENOG4105CGA	flagellar basal-body rod protein FlgG
CH48_2335	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CH48_2341	ENOG4108M3R	transcriptional activator CadC
CH48_2342	ENOG4105I03	Flagellin
CH48_2343	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
CH48_2344	ENOG4105MQ3	flagellar protein FliS
CH48_2349	ENOG4107RD7	Flagellar Motor Protein, MotA
CH48_235	ENOG4105PBD	transposase, IS3 IS911 family protein
CH48_2351	ENOG4108XTF	Outer Membrane Lipoprotein
CH48_2353	ENOG4105E3S	small subunit
CH48_2354	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CH48_2355	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
CH48_2356	ENOG4105DPX	Hydrogenase, large subunit
CH48_2357	ENOG4108USZ	hydrogenase
CH48_2358	ENOG4108WGS	hydrogenase 2-specific chaperone
CH48_2359	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CH48_2360	ENOG4107RSS	Hydrogenase accessory protein HypB
CH48_2361	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
CH48_2362	ENOG4105CQS	hydrogenase expression formation protein HypD
CH48_2363	ENOG4105C45	hydrogenase expression formation protein (HypE)
CH48_2364	ENOG4105C8H	hydrogenase maturation protein Hypf
CH48_2365	ENOG4107R3N	Filamentation induced by cAMP protein fic
CH48_2366	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
CH48_2369	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CH48_2372	ENOG4105CSH	Transporter
CH48_2375	ENOG4105EAM	Na Pi-cotransporter
CH48_2377	ENOG4105ETE	Transcriptional regulator (LacI family
CH48_2379	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CH48_2381	ENOG4105T38	integral membrane protein
CH48_2386	ENOG4105CM4	permease protein
CH48_2387	ENOG4108IPW	abc transporter atp-binding protein
CH48_2388	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CH48_239	ENOG4108UHE	carbonic anhydrase
CH48_2392	ENOG4105J12	Multidrug resistance protein mdtN
CH48_2393	ENOG4108MI0	Resistance protein
CH48_2395	ENOG4105CXN	decarboxylase
CH48_2396	ENOG4105D5Q	Arginine ornithine antiporter
CH48_240	ENOG4105CS2	ec 3.2.1.21
CH48_2408	ENOG4105CXN	decarboxylase
CH48_241	ENOG4105C5Y	PTS System
CH48_2410	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CH48_2411	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CH48_2412	ENOG4105CEN	a g-specific adenine glycosylase
CH48_2413	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CH48_2414	ENOG41090ED	Protein with unknown function (DUF469)
CH48_2415	ENOG4105CSV	Glutaminase
CH48_2416	ENOG4105K33	Periplasmic Protein
CH48_2417	ENOG4105CSA	Coproporphyrinogen iii oxidase
CH48_2418	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CH48_2419	ENOG4105VZ9	UPF0235 protein
CH48_242	ENOG4108Q3X	Transcriptional regulator
CH48_2420	ENOG4108VIA	integral membrane protein
CH48_2421	ENOG4105II7	pyrroline-5-carboxylate reductase
CH48_2422	ENOG4105DFA	alanine racemase domain protein
CH48_2423	ENOG4105CZX	twitching motility protein
CH48_2425	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
CH48_2426	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CH48_2427	ENOG4108UJU	UPF0301 protein
CH48_2428	ENOG4105D7Z	glutathione synthase
CH48_2429	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CH48_2430	ENOG4105RWS	endonuclease I
CH48_2431	ENOG4105GPY	SprT protein
CH48_2432	ENOG41080HT	Transcriptional regulator, arsr family
CH48_2435	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CH48_2438	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CH48_2440	ENOG4108K0D	peptidase, M48
CH48_2441	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CH48_2442	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CH48_2443	ENOG4105BZA	Phosphoglycerate kinase
CH48_2444	ENOG4105D2N	Aldolase
CH48_2446	ENOG4105D64	Mechanosensitive ion channel
CH48_2449	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
CH48_2450	ENOG4105MPN	Membrane
CH48_2451	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
CH48_2452	ENOG4105E66	phosphoriboisomerase A
CH48_2453	ENOG4108JQ1	Dehydrogenase
CH48_2460	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CH48_2463	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CH48_2464	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CH48_2465	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CH48_2466	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CH48_2469	ENOG4108MXK	alkaline phosphatase isozyme conversion
CH48_247	ENOG4105HRS	Antitermination protein
CH48_2470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CH48_2471	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CH48_2472	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CH48_2473	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
CH48_2474	ENOG4105N0Z	inner membrane protein ygbE
CH48_2475	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CH48_2477	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CH48_2478	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CH48_2479	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CH48_2480	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CH48_2481	ENOG4108K5P	(LipO)protein
CH48_2482	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CH48_2483	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CH48_2491	ENOG4108FZ9	Chaperone
CH48_2493	ENOG4105UGQ	Fimbrial
CH48_2494	ENOG4105H8W	Fimbrial protein
CH48_25	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CH48_250	ENOG4105Y50	Virulence Protein
CH48_2500	ENOG4108JJA	ABC, transporter
CH48_2501	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CH48_2503	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CH48_2504	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CH48_2507	ENOG4105CHR	reductase
CH48_2509	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CH48_2510	ENOG4105CA0	peroxidase
CH48_2512	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CH48_2513	ENOG4105YVS	arsR family transcriptional regulator
CH48_2514	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
CH48_2515	ENOG4105F3R	pts system mannose fructose sorbose family iid
CH48_2516	ENOG4105ETZ	PTS System
CH48_2517	ENOG4105KPI	PTS system sorbose subfamily IIB component
CH48_2518	ENOG4108XCU	pts system
CH48_2519	ENOG4105DKT	Transcriptional regulator
CH48_252	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_2524	ENOG4108IV0	ABC, transporter
CH48_2525	ENOG4108IUZ	ABC transporter
CH48_2526	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CH48_2527	ENOG4105C32	Amino acid ABC transporter (Permease)
CH48_2529	ENOG4107GFK	fumarate
CH48_2530	ENOG4107QY8	reductase
CH48_2531	ENOG4105QAX	Iron-sulfur
CH48_2532	ENOG4107KGK	dmso reductase anchor subunit
CH48_2533	ENOG4108NEM	leader-binding protein dmsD
CH48_2538	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CH48_2539	ENOG4105Y3E	Modulates RecA activity (By similarity)
CH48_254	ENOG4105CT4	transporter
CH48_2540	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CH48_2541	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CH48_2546	ENOG4107VXZ	Hydrolase
CH48_2547	ENOG4105W39	Membrane
CH48_2548	ENOG4105D9M	gamma-glutamylcysteine synthetase
CH48_2549	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CH48_255	ENOG4107R6D	beta-lactam binding protein AmpH
CH48_2551	ENOG4108JU6	CBS domain protein
CH48_2552	ENOG4106KVJ	cytochrome C assembly protein
CH48_2553	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH48_2554	ENOG4105K5M	30s ribosomal protein S16
CH48_2555	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CH48_2556	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CH48_2557	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CH48_2558	ENOG4108NE3	Salt-induced outer membrane protein
CH48_2559	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CH48_2560	ENOG4108NEV	two component transcriptional regulator, LytTR family
CH48_2561	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CH48_2562	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CH48_2563	ENOG4105CQC	Prephenate dehydratase
CH48_2564	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_2565	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_2566	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CH48_2567	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CH48_2568	ENOG4105C34	Pseudouridine synthase
CH48_2569	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH48_2570	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
CH48_2577	ENOG4105T42	(LipO)protein
CH48_2578	ENOG4105JIM	Phosphatidylserine synthase
CH48_2579	ENOG4105CD5	CoA-binding domain protein
CH48_2580	ENOG4106IUH	DTW domain containing protein
CH48_2581	ENOG4105K63	Thioredoxin
CH48_2582	ENOG4105EIB	trna rrna methyltransferase
CH48_2584	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CH48_2585	ENOG4105CW7	secretion protein, HlyD family
CH48_2586	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
CH48_2587	ENOG4105NTK	Transcriptional repressor Mpra
CH48_2588	ENOG4105ZED	uncharacterized protein ygaH
CH48_2589	ENOG4108UMN	azlc family
CH48_259	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CH48_2590	ENOG4105EQ0	Major Facilitator superfamily
CH48_2598	ENOG4105E5Q	amino acid AbC transporter
CH48_2599	ENOG4105E5Q	amino acid AbC transporter
CH48_26	ENOG4106AFQ	Histidine kinase
CH48_2601	ENOG4105C5R	Aminotransferase
CH48_2604	ENOG4105CHM	Aminotransferase
CH48_2605	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
CH48_2606	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
CH48_2607	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
CH48_2608	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CH48_2609	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
CH48_261	ENOG4106UW1	Major Facilitator superfamily
CH48_2610	ENOG4108D1Y	Polypeptide-transport-associated domain protein, ShlB-type
CH48_2612	ENOG4106YJS	accessory processing protein
CH48_2613	ENOG4107QPN	acyl-Coa dehydrogenase
CH48_2615	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
CH48_2616	ENOG4105E7A	Glutamine amidotransferase
CH48_2617	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CH48_2618	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CH48_2619	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CH48_262	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
CH48_2620	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CH48_2621	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CH48_2622	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
CH48_2623	ENOG4105CJ2	(LipO)protein
CH48_2626	ENOG4105CPF	Cell wall formation (By similarity)
CH48_2627	ENOG4105WWK	YheO domain protein
CH48_263	ENOG41068CG	regulatoR
CH48_2630	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CH48_2631	ENOG4105CIN	aminoacyl-histidine dipeptidase
CH48_2632	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CH48_2633	ENOG4105V1F	Fermentation respiration switch protein
CH48_2634	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
CH48_2635	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CH48_2636	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CH48_2637	ENOG4105FDP	GntR family transcriptional regulator
CH48_2638	ENOG4105CI1	PTS System
CH48_2639	ENOG4105F8D	glycoside hydrolase family 4
CH48_264	ENOG4105BZU	Histidine kinase
CH48_2641	ENOG4105E2V	Glycosyltransferase 36
CH48_2644	ENOG4105F2W	methyltransferase
CH48_2649	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CH48_2650	ENOG4105NBK	UPF0345 protein
CH48_2651	ENOG4105DH7	May be involved in recombination (By similarity)
CH48_2652	ENOG4105DKQ	ROK family
CH48_2653	ENOG4105EYH	Exonuclease
CH48_2654	ENOG4107RH8	nuclease SbcCD subunit D
CH48_2655	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CH48_2656	ENOG4105BZU	Histidine kinase
CH48_2658	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CH48_2659	ENOG4105C85	amino acid
CH48_266	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CH48_2660	ENOG4107R28	alpha amylase, catalytic region
CH48_2661	ENOG4105CHR	reductase
CH48_2663	ENOG41074AV	Hok/gef family
CH48_2664	ENOG4105D3R	alkyl hydroperoxide reductase
CH48_2665	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
CH48_2666	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CH48_2669	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CH48_267	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CH48_2670	ENOG4105VIE	preprotein translocase, subunit YajC
CH48_2671	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CH48_2672	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CH48_2676	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CH48_2677	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CH48_2678	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CH48_2679	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CH48_268	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CH48_2680	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CH48_2681	ENOG4108ZAI	phosphatidylglycerophosphatase a
CH48_2683	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CH48_2684	ENOG4105CTB	Polyprenyl synthetase
CH48_2686	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CH48_2687	ENOG4107S0N	DJ-1 family
CH48_2688	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CH48_2689	ENOG4108VPT	UPF0234 protein
CH48_269	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CH48_2690	ENOG4107RDB	Major Facilitator
CH48_2691	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CH48_2692	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
CH48_2693	ENOG4105CCU	oxidase (Subunit III)
CH48_2694	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CH48_2695	ENOG4105E2S	oxidase) subunit II
CH48_2696	ENOG4108NFH	Sugar hydrolase
CH48_2697	ENOG4105EYM	Major Facilitator superfamily
CH48_2698	ENOG4105IEY	(LipO)protein
CH48_2699	ENOG4105M85	Bola protein
CH48_27	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CH48_270	ENOG4105XPH	Ferredoxin
CH48_2700	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CH48_2701	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CH48_2702	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CH48_2703	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CH48_2704	ENOG4105K70	DNA-binding protein
CH48_2706	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CH48_2707	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CH48_2708	ENOG4108TGP	Thioesterase superfamily protein
CH48_2709	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CH48_271	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
CH48_2710	ENOG4108NFA	extracellular solute-binding protein
CH48_2711	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
CH48_2713	ENOG4108XM1	transcriptional regulator AsnC family
CH48_2714	ENOG4105BZ1	(ABC) transporter
CH48_2715	ENOG4105BZ1	(ABC) transporter
CH48_2716	ENOG4108YZA	Nitrogen regulatory protein pii
CH48_2717	ENOG4105BZU	Histidine kinase
CH48_2718	ENOG4105C29	acyl-CoA thioesterase
CH48_2719	ENOG4108MNP	Glycoprotein polysaccharide metabolism
CH48_2720	ENOG41080UX	Methyltransferase
CH48_2721	ENOG4105KF5	hemolysin expression-modulating protein
CH48_2722	ENOG4108UKR	Biofilm formation regulator YbaJ
CH48_2725	ENOG4105DIK	(ABC) transporter
CH48_2726	ENOG4105CC5	ABC transporter
CH48_2727	ENOG4105DSE	periplasmic solute binding protein
CH48_2728	ENOG4105YK5	50S ribosomal protein L36
CH48_2729	ENOG4105NRA	50s ribosomal protein l31 type b
CH48_2731	ENOG4105MUZ	Protein of unknown function DUF2620
CH48_2732	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CH48_2733	ENOG4108626	Racemase
CH48_2735	ENOG4105BZS	acriflavin resistance protein
CH48_2736	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CH48_2737	ENOG4108IG5	Transcriptional regulator
CH48_2738	ENOG41090EX	DsrE family
CH48_2740	ENOG4105EGS	Mechanosensitive ion channel
CH48_2742	ENOG4105WD1	Membrane
CH48_2743	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CH48_2744	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CH48_2745	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CH48_2746	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CH48_2747	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CH48_2748	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CH48_2749	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CH48_2750	ENOG4105ER6	polysaccharide biosynthesis protein
CH48_2752	ENOG4108SHN	Glycosyl transferase, family 2
CH48_2753	ENOG4105CG5	Glycosyl transferase (Group 1
CH48_2754	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CH48_2755	ENOG4105ESV	Glycosyl transferase, family 4
CH48_2758	ENOG4105CMR	udp-glucose 4-epimerase
CH48_2759	ENOG4107RE1	Inosine-guanosine kinase
CH48_276	ENOG4105E0U	tyrosine-specific transport protein
CH48_2760	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CH48_2761	ENOG4105EU0	Major facilitator Superfamily
CH48_2762	ENOG4105CGH	5'-nucleotidase
CH48_2764	ENOG4108Z66	YbaK ebsC protein
CH48_2765	ENOG4105MBR	gumn family
CH48_2766	ENOG4105C59	p-type ATPase
CH48_2767	ENOG4108Z6Z	Transcriptional regulator
CH48_2768	ENOG4105G5H	Membrane
CH48_2769	ENOG4107QX8	SPFH domain, Band 7 family protein
CH48_277	ENOG4108UII	YfaZ family
CH48_2770	ENOG4107QR8	Thioredoxin
CH48_2771	ENOG4105E1F	short-chain dehydrogenase reductase
CH48_2772	ENOG4108UJV	acyl-CoA thioesterase i
CH48_2773	ENOG4108I0Y	(ABC) transporter
CH48_2774	ENOG4105CV6	ABC transporter, permease
CH48_2775	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CH48_2776	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CH48_2777	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CH48_2778	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CH48_2779	ENOG4105C8N	cysteinyl-tRNA synthetase
CH48_278	ENOG4105CH6	catalase
CH48_2780	ENOG4105WQ3	Rna-binding protein
CH48_2781	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CH48_2783	ENOG4108KU3	Integrase
CH48_279	ENOG4105CEY	Amp-dependent synthetase and ligase
CH48_2791	ENOG4105EZE	Cupin 4 family protein
CH48_2792	ENOG4105C84	Histidine ammonia-lyase
CH48_2793	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CH48_2795	ENOG4108JJ7	ABC transporter
CH48_2798	ENOG4108R1E	Serine threonine protein phosphatase 1
CH48_28	ENOG4105D1S	lipid A biosynthesis
CH48_280	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
CH48_2800	ENOG4108N8T	regulatoR
CH48_2802	ENOG4105VEQ	Cold shock protein
CH48_2803	ENOG4107Z6W	Protein CrcB homolog
CH48_2804	ENOG4105BZU	Histidine kinase
CH48_2805	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
CH48_2806	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CH48_2807	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CH48_2808	ENOG4108Z43	UPF0250 protein
CH48_2809	ENOG4105DZ1	carboxypeptidase
CH48_281	ENOG4108IPT	Naphthoate synthase
CH48_2810	ENOG4105K6T	rare lipoprotein A
CH48_2811	ENOG4105CNI	cell division protein FtsW
CH48_2812	ENOG4105CJN	penicillin-binding protein
CH48_2814	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CH48_2815	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CH48_2816	ENOG4105DJF	DNA polymerase III, delta' subunit
CH48_2817	ENOG4108U2H	Rare lipoprotein B
CH48_2818	ENOG4105C8T	Leucyl-tRNA synthetase
CH48_2819	ENOG4107PAI	alpha helical protein
CH48_282	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
CH48_2820	ENOG4105CDA	abc transporter atp-binding protein
CH48_2821	ENOG4105DRP	amino acid AbC transporter
CH48_2822	ENOG4105EAD	ABC transporter
CH48_2823	ENOG4107RP9	extracellular solute-binding protein, family 3
CH48_2825	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CH48_2826	ENOG4108JU5	Magnesium and cobalt efflux protein
CH48_2827	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CH48_2828	ENOG4105C9A	Phoh family
CH48_2829	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CH48_283	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CH48_2830	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CH48_2837	ENOG4105CAQ	asparagine synthetase
CH48_2838	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
CH48_2839	ENOG4105E2R	ROK family
CH48_284	ENOG4105E4F	Isochorismate synthase
CH48_2840	ENOG4105CE4	GlcNAc 6-P deacetylase
CH48_2841	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CH48_2842	ENOG4105CI1	PTS System
CH48_2843	ENOG4105CX6	glutaminyL-tRNA synthetase
CH48_2845	ENOG4105GX6	(LipO)protein
CH48_2847	ENOG41090R7	Ferric uptake
CH48_2848	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CH48_2849	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_285	ENOG4105D5G	Transposase
CH48_2850	ENOG4105NNH	LexA regulated protein
CH48_2852	ENOG4105EV9	Alpha Beta Hydrolase
CH48_2854	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CH48_2857	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CH48_2858	ENOG4105C08	Histidine kinase
CH48_2859	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CH48_286	ENOG4105TNS	Conserved Protein
CH48_2860	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CH48_2861	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CH48_2862	ENOG4105XIQ	Protein of unknown function (DUF2517)
CH48_2864	ENOG4108RC6	RTX toxin
CH48_2865	ENOG4105EUK	rtx toxin RtxA
CH48_2865	ENOG4105EUK	rtx toxin RtxA
CH48_2866	ENOG4107SEY	Conserved Protein
CH48_2867	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CH48_2868	ENOG4107RF4	Phosphodiesterase
CH48_2869	ENOG4107QNR	UPF0135 protein
CH48_2871	ENOG4105P4J	Allophanate hydrolase, subunit 1
CH48_2872	ENOG4107R7A	Allophanate hydrolase subunit 2
CH48_2873	ENOG4105E7W	lamb ycsf family protein
CH48_2876	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
CH48_2877	ENOG4105BZN	citrate synthase
CH48_2878	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
CH48_2879	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
CH48_2881	ENOG4105E33	succinate dehydrogenase
CH48_2882	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CH48_2883	ENOG4105C7S	Dehydrogenase
CH48_2884	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CH48_2885	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CH48_2887	ENOG4105CGH	5'-nucleotidase
CH48_2888	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CH48_2889	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CH48_289	ENOG41090KN	UPF0303 protein
CH48_2891	ENOG4105KJB	cyd operon protein YbgE
CH48_2892	ENOG4107YD3	Thioesterase
CH48_2893	ENOG4105E02	MotA TolQ exbB proton channel
CH48_2894	ENOG4105M8F	Biopolymer transport protein exbD tolR
CH48_2895	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
CH48_2895	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
CH48_2896	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CH48_2897	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CH48_2898	ENOG4105UFD	tol-pal system protein YbgF
CH48_2903	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CH48_2904	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
CH48_2905	ENOG4105PGM	cation diffusion facilitator family transporter
CH48_2906	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CH48_2907	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CH48_291	ENOG4105C5I	Dehydrogenase
CH48_2912	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CH48_2913	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CH48_2914	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CH48_2915	ENOG4105CMR	udp-glucose 4-epimerase
CH48_2917	ENOG4105DKW	ABC transporter
CH48_2918	ENOG4105F4R	Transcriptional regulator mode
CH48_2919	ENOG410680R	Protein of unknown function (DUF2592)
CH48_2920	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CH48_2922	ENOG4105DFP	Integrase
CH48_294	ENOG4105CHR	reductase
CH48_295	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CH48_2960	ENOG4105E0C	molybdate abc transporter
CH48_2962	ENOG4108K4B	hydrolase
CH48_2963	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CH48_2965	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CH48_2966	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CH48_2967	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CH48_2968	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CH48_297	ENOG4108UQ5	membrane protein YcdZ
CH48_2970	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CH48_2971	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CH48_2972	ENOG4105CHW	UPF0052 protein
CH48_2973	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CH48_2974	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CH48_2975	ENOG4105M00	molybdopterin converting factor, subunit 1
CH48_2976	ENOG4108ZAF	Molybdopterin
CH48_2977	ENOG4105HFZ	Membrane
CH48_2978	ENOG4107QWP	ABC-2 type transporter
CH48_2979	ENOG4107QWP	ABC-2 type transporter
CH48_2980	ENOG4105CJ1	ABC, transporter
CH48_2981	ENOG4105D0S	secretion protein (HlyD
CH48_2982	ENOG4107MVR	Transcriptional regulator
CH48_2983	ENOG4105C1J	atp-dependent rna helicase
CH48_2984	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CH48_2986	ENOG4105CJW	magnesium transporter
CH48_2988	ENOG41061WM	D-Alanyl-D-Alanine
CH48_2989	ENOG4105CXG	d-lactate dehydrogenase
CH48_299	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CH48_2991	ENOG4105N1F	Hnh endonuclease
CH48_2993	ENOG4105Y3U	Transglycosylase-associated protein
CH48_2995	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
CH48_2998	ENOG4108W15	Protein of unknown function (DUF1456)
CH48_300	ENOG4105C8S	subunit m
CH48_3000	ENOG4105C32	Amino acid ABC transporter (Permease)
CH48_3001	ENOG4105CNN	ABC, transporter
CH48_3002	ENOG4105D5T	phosphonate abc transporter
CH48_3003	ENOG4108IV0	ABC, transporter
CH48_3004	ENOG4105KHC	sulfurtransferase
CH48_3005	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CH48_3007	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
CH48_3008	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
CH48_3009	ENOG4108IJ8	ABC transporter
CH48_301	ENOG4105D65	subunit l
CH48_3010	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
CH48_3012	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CH48_3014	ENOG4105HEI	LysR family (Transcriptional regulator
CH48_3015	ENOG4105FDR	Membrane
CH48_3018	ENOG4105DVT	helicase
CH48_3019	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CH48_302	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CH48_3020	ENOG4108MTB	glycosyl transferase family
CH48_3024	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
CH48_3025	ENOG4107SDU	Methyl-accepting chemotaxis
CH48_3026	ENOG4105CDA	abc transporter atp-binding protein
CH48_3027	ENOG4105E5Q	amino acid AbC transporter
CH48_3028	ENOG4107R0W	ABC transporter
CH48_3029	ENOG4105KSC	Transcriptional regulator, TraR DksA family
CH48_303	ENOG4107UFS	subunit j
CH48_3030	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
CH48_3031	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CH48_3037	ENOG4108T1M	outer membrane protein x
CH48_304	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CH48_3041	ENOG4105C5H	ABC transporter
CH48_3043	ENOG4105D06	uba thif-type nad fad binding protein
CH48_3044	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CH48_3047	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CH48_305	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CH48_3053	ENOG4105EGI	Transcriptional regulator
CH48_3054	ENOG4105CBP	Major Facilitator
CH48_3055	ENOG4105EUJ	GTP cyclohydrolase i
CH48_3056	ENOG4105DHF	Membrane
CH48_3057	ENOG41060NJ	transcriptional regulator
CH48_306	ENOG4108IEH	NADH dehydrogenase subunit g
CH48_3060	ENOG4107SDZ	Galactoside transport system permease protein mglC
CH48_3061	ENOG4108JUA	Transcriptional regulator
CH48_3062	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CH48_3063	ENOG4108RC0	Electron transport protein
CH48_3064	ENOG4108MG9	hydrogenase 3 maturation protease
CH48_3065	ENOG4105I6X	formate hydrogenlyase maturation
CH48_3066	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
CH48_3068	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CH48_3069	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CH48_307	ENOG4107QIZ	NADH dehydrogenase
CH48_3070	ENOG4107WQX	hydrogenase 4 membrane subunit
CH48_3071	ENOG4105D65	subunit l
CH48_3072	ENOG4107TDF	Formate hydrogenlyase subunit 4
CH48_3073	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CH48_3074	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
CH48_3075	ENOG410816D	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CH48_3077	ENOG4107GZ4	SanA protein
CH48_3078	ENOG4107R1I	NAD-dependent malic enzyme
CH48_308	ENOG4105GKE	subunit e
CH48_3081	ENOG41067MG	lrgb family
CH48_3082	ENOG4105VAW	lrga family
CH48_3083	ENOG4105E5W	Transporter
CH48_3087	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CH48_3088	ENOG4105D1F	ATP-binding protein
CH48_3089	ENOG4105DBI	uridine monophosphokinase
CH48_309	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CH48_3091	ENOG4108GAE	asmA family
CH48_3092	ENOG4105CEE	C4-dicarboxylate transporter
CH48_3093	ENOG4105EE5	Membrane protein terC
CH48_3096	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CH48_3097	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CH48_3098	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CH48_3099	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CH48_31	ENOG4108VGI	doxx family
CH48_310	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CH48_3104	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CH48_3106	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CH48_3107	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CH48_3108	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CH48_3109	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CH48_311	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CH48_3110	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CH48_3111	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CH48_3112	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CH48_3114	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CH48_3115	ENOG4108535	NAD dependent epimerase/dehydratase family
CH48_3117	ENOG4105CNN	ABC, transporter
CH48_3118	ENOG4105C2J	ABC transporter
CH48_312	ENOG4107NQ8	LysR family Transcriptional regulator
CH48_3122	ENOG4105CUB	amino acid
CH48_3123	ENOG4105CJB	Exodeoxyribonuclease I
CH48_3124	ENOG4105E4E	Thioester reductase domain-containing protein
CH48_3125	ENOG4105DR8	Membrane
CH48_3126	ENOG41090HJ	UPF0265 protein
CH48_3128	ENOG4105CNN	ABC, transporter
CH48_3129	ENOG4105C2J	ABC transporter
CH48_313	ENOG4105CHM	Aminotransferase
CH48_3130	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CH48_3131	ENOG4105JZC	GHMP kinase
CH48_3132	ENOG4107QZB	decarboxylase
CH48_3133	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CH48_3134	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CH48_3135	ENOG4105KTW	ethanolamine utilization protein
CH48_3136	ENOG4105M3W	utilization protein
CH48_3138	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CH48_314	ENOG4105DK2	UPF0207 protein
CH48_3140	ENOG4108EKI	Dehydrogenase
CH48_3142	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CH48_3144	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
CH48_3146	ENOG4105KNY	Microcompartments protein
CH48_3148	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
CH48_315	ENOG4107QWE	)-transporter
CH48_3150	ENOG4108ZFT	Dehydratase small subunit
CH48_3151	ENOG4105YCI	dehydratase medium subunit
CH48_3152	ENOG4105DMB	glycerol dehydratase
CH48_3153	ENOG4105EHR	propanediol utilization protein pduB
CH48_3154	ENOG4105KNY	Microcompartments protein
CH48_3155	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CH48_3156	ENOG4107XVH	Transcriptional regulator
CH48_3157	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CH48_3158	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CH48_3159	ENOG41081F0	Precorrin-8x methylmutase
CH48_3160	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CH48_3161	ENOG4108DR9	Cobalt-precorrin-6Y C(5)-methyltransferase
CH48_3162	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
CH48_3163	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CH48_3164	ENOG4108P62	biosynthesis protein (CbiG)
CH48_3165	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CH48_3166	ENOG4105QUC	reductase
CH48_3167	ENOG4107PPM	cobalt chelatase
CH48_3168	ENOG4105DVK	Precorrin-2 c20-methyltransferase
CH48_3169	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
CH48_317	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
CH48_3170	ENOG4105W4R	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
CH48_3171	ENOG4108V4M	Cobalt abc transporter
CH48_3173	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CH48_3174	ENOG4108YZT	Adenosylcobinamide kinase
CH48_3175	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CH48_3176	ENOG4108TGR	phosphatase
CH48_3177	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CH48_3178	ENOG4105EAA	nucleoside
CH48_318	ENOG4105XWI	UPF0304 protein
CH48_3188	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CH48_3189	ENOG4106EAR	Fimbrial protein
CH48_319	ENOG4105PQ6	UPF0208 membrane protein
CH48_3190	ENOG4108VEV	chaperone
CH48_3191	ENOG4105CW0	outer membrane usher protein
CH48_3200	ENOG4105CS6	Rhs element vgr protein
CH48_3205	ENOG4105CDH	Citrulline--aspartate ligase
CH48_3206	ENOG4105UQX	Mate efflux family protein
CH48_3208	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CH48_3209	ENOG410667J	hydrolase
CH48_321	ENOG4105C6K	Malic enzyme
CH48_3210	ENOG4105E98	transcriptional regulator DeoR family
CH48_3211	ENOG4107S1E	Beta-lactamase
CH48_3212	ENOG4107R88	Chemotaxis protein (CheV)
CH48_3214	ENOG4105EMU	Dehydrogenase
CH48_3218	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CH48_3219	ENOG4107RCV	ABC transporter, permease
CH48_322	ENOG4107P2S	Transcriptional regulator
CH48_3220	ENOG4105C4Y	ABC transporter
CH48_3221	ENOG4105CXY	transporter
CH48_3222	ENOG4105BZU	Histidine kinase
CH48_3223	ENOG4108KX4	response regulator
CH48_3224	ENOG4106YYS	transcriptional regulatory protein
CH48_3226	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CH48_3229	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
CH48_323	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
CH48_3230	ENOG4105CI0	Citrate lyase
CH48_3231	ENOG4105CHY	citrate lyase, alpha
CH48_3232	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
CH48_3233	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
CH48_3234	ENOG4107QPK	)-transporter
CH48_3235	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CH48_3237	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CH48_3238	ENOG4108TSE	Transferase
CH48_3240	ENOG4105C54	Major Facilitator superfamily
CH48_3241	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CH48_3242	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
CH48_3243	ENOG4105D3G	Pseudouridine synthase
CH48_3246	ENOG4108MQF	Chaperone
CH48_325	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
CH48_3251	ENOG4105BZU	Histidine kinase
CH48_3252	ENOG4108Q9V	regulatoR
CH48_3254	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
CH48_3255	ENOG4105CMG	Carbohydrate kinase
CH48_3260	ENOG4108D1K	outer membrane usher protein
CH48_3261	ENOG4108S1B	Periplasmic chaperone protein
CH48_3266	ENOG4105D6F	Phosphatase
CH48_3267	ENOG41061EV	selenium-binding protein YdfZ
CH48_3270	ENOG4105GSJ	Inner membrane protein ylaC
CH48_3273	ENOG4105D5G	Transposase
CH48_3274	ENOG4105CNT	hydrolase family 2
CH48_3275	ENOG4105ETE	Transcriptional regulator (LacI family
CH48_3276	ENOG4105VEQ	Cold shock protein
CH48_3278	ENOG4105VZF	DsrB protein
CH48_3279	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_328	ENOG4105PTV	Nudix Hydrolase
CH48_3282	ENOG4105KT7	mgtC SapB transporter
CH48_3283	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CH48_3284	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CH48_3285	ENOG4108VA4	Universal stress protein
CH48_3286	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
CH48_3287	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
CH48_3288	ENOG4107RD7	Flagellar Motor Protein, MotA
CH48_3289	ENOG4105ER2	Ompa motb domain protein
CH48_329	ENOG4108RE9	Phosphodiesterase
CH48_3290	ENOG4105CBS	Chea signal transduction histidine kinase
CH48_3291	ENOG4108V3W	Chemotaxis protein, CheW
CH48_3292	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_3293	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_3294	ENOG4105BZU	Histidine kinase
CH48_3296	ENOG4108VYJ	response regulator receiver protein
CH48_3297	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CH48_3298	ENOG4107VE4	peptidase S8 and S53, subtilisin, kexin, sedolisin
CH48_3299	ENOG4105D00	flagellar biosynthetic protein flhB
CH48_3300	ENOG4105D7B	Flagellar biosynthesis protein flha
CH48_3301	ENOG4105W13	flagellar protein
CH48_3303	ENOG4105QVD	Flagella synthesis protein FlgN
CH48_3304	ENOG4105TNG	K13735 adhesin invasin
CH48_3305	ENOG4105M9M	anti-sigma28 factor FlgM
CH48_3306	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
CH48_3307	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CH48_3308	ENOG4108ZC9	flagellar basal-body rod protein flgc
CH48_3309	ENOG4105W00	Flagellar hook capping protein
CH48_331	ENOG4105ECP	epimerase
CH48_3310	ENOG4105BZE	flagellar hook protein, FlgE
CH48_3311	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CH48_3312	ENOG4105CGA	flagellar basal-body rod protein FlgG
CH48_3315	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CH48_3316	ENOG4105E1Q	flagellar hook-associated protein
CH48_3317	ENOG4105DTJ	flagellar hook-associated protein
CH48_3318	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CH48_3319	ENOG4105VS8	Flagellar biosynthetic protein fliq
CH48_3320	ENOG4105CN7	Flagellar biosynthetic protein FliP
CH48_3322	ENOG4105DD5	Flagellar motor switch protein
CH48_3323	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CH48_3324	ENOG4107ZI8	flagellar basal body-associated protein flil
CH48_3325	ENOG4105WF4	Flagellar hook-length control protein
CH48_3326	ENOG4105GSA	Flagellar export protein flij
CH48_3327	ENOG4108JIR	Flagellum-specific ATP synthase
CH48_3328	ENOG41090PJ	Flagellar assembly protein
CH48_3329	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CH48_333	ENOG4108JEH	abc transporter atp-binding protein
CH48_3330	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CH48_3331	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CH48_3337	ENOG4105DHT	Metal Dependent Phosphohydrolase
CH48_3339	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
CH48_334	ENOG4106YG3	ABC transporter
CH48_3340	ENOG4105MQ3	flagellar protein FliS
CH48_3341	ENOG4105DTS	flagellar hook-associated
CH48_3342	ENOG4105I03	Flagellin
CH48_3345	ENOG4108C80	FliB family
CH48_3346	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CH48_3347	ENOG4108M9K	flagella biosynthesis protein FliZ
CH48_3348	ENOG4105K6H	D-cysteine desulfhydrase
CH48_3349	ENOG4105EAB	amino acid AbC transporter
CH48_335	ENOG4105DSP	amino acid AbC transporter
CH48_3350	ENOG4105E5Q	amino acid AbC transporter
CH48_3351	ENOG4105CDA	abc transporter atp-binding protein
CH48_3355	ENOG4105C26	Dehydrogenase
CH48_3356	ENOG4105CK7	Sodium proline symporter
CH48_3359	ENOG4105GMB	type VI secretion system effector, hcp1 family
CH48_336	ENOG4105E89	ABC transporter
CH48_3363	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CH48_3365	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
CH48_3366	ENOG4105C2W	permease
CH48_3369	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
CH48_337	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CH48_3370	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
CH48_3371	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CH48_3372	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
CH48_3373	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CH48_3374	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
CH48_3375	ENOG4108R86	Transcriptional regulator
CH48_3376	ENOG4105C85	amino acid
CH48_3379	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CH48_338	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CH48_3382	ENOG4105E5K	Alpha-amylase
CH48_3384	ENOG4105RA2	Membrane
CH48_3385	ENOG4105XVG	cytoplasmic protein
CH48_3386	ENOG4105WH1	Two component transcriptional regulator luxr family
CH48_3387	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CH48_3388	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CH48_339	ENOG4105E96	Colicin v production protein
CH48_3392	ENOG4105ZTC	transcriptional activator, Ogr delta
CH48_34	ENOG4105DUX	Transporter
CH48_340	ENOG4108S3P	Sporulation domain protein
CH48_3407	ENOG4105VXN	addiction module toxin, RelE StbE family
CH48_341	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CH48_342	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CH48_3427	ENOG4105D5G	Transposase
CH48_3429	ENOG4105EXG	Transcriptional regulator
CH48_343	ENOG4105DQR	SNARE associated Golgi
CH48_3435	ENOG4105HRS	Antitermination protein
CH48_3437	ENOG4105KUS	lysozyme
CH48_3439	ENOG4108Q2J	Inner membrane protein YebE
CH48_3441	ENOG41066YJ	Beta-lactamase
CH48_3442	ENOG4105C3G	gtp-binding protein
CH48_3444	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CH48_3445	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
CH48_3447	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CH48_3449	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
CH48_345	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CH48_3450	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CH48_3451	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CH48_3452	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CH48_3453	ENOG4108YY7	Invasion gene expression up-regulator SirB
CH48_3454	ENOG41063JG	Transcriptional regulator
CH48_3455	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CH48_3456	ENOG4105CHH	sulfate transporter
CH48_3458	ENOG4105BZU	Histidine kinase
CH48_3462	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
CH48_3463	ENOG4107SSZ	Phosphatase
CH48_3464	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
CH48_3465	ENOG4105F3T	(LipO)protein
CH48_3466	ENOG4105EV4	Multidrug resistance protein mdtH
CH48_3469	ENOG4105D9U	N-acetyltransferase
CH48_3471	ENOG4105EP9	oxidoreductase
CH48_3472	ENOG4105CJR	Integral membrane protein (MviN
CH48_3473	ENOG4105EWV	Sodium calcium exchanger membrane region
CH48_3477	ENOG4107R11	Transcriptional regulator
CH48_3478	ENOG4105BZU	Histidine kinase
CH48_3479	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CH48_348	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CH48_3480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CH48_3481	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CH48_3482	ENOG4105C8Y	Acetylornithine aminotransferase
CH48_3483	ENOG4105F4X	arginine
CH48_3485	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
CH48_3486	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
CH48_3492	ENOG4105CI2	imidazolone-5-propionate hydrolase
CH48_3493	ENOG4105CZE	histidine utilization repressor
CH48_3494	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CH48_3495	ENOG41090B9	response to stress
CH48_3496	ENOG4108MEK	Metal-binding protein YodA
CH48_350	ENOG410631K	Membrane
CH48_3500	ENOG4108K5P	(LipO)protein
CH48_3501	ENOG4105D2N	Aldolase
CH48_3502	ENOG4105E70	isomerase
CH48_3503	ENOG4108YTN	IIa component
CH48_3504	ENOG4105F3R	pts system mannose fructose sorbose family iid
CH48_3506	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
CH48_3507	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CH48_3508	ENOG4105E98	transcriptional regulator DeoR family
CH48_3512	ENOG4105FE9	pseudouridine synthase
CH48_3513	ENOG4105D6U	Sodium Glutamate Symporter
CH48_3515	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_3516	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_3517	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CH48_3518	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CH48_3519	ENOG4105WJG	Glutathione
CH48_352	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CH48_3520	ENOG41081XQ	Conserved Protein
CH48_3521	ENOG4105D3W	isochorismatase
CH48_3522	ENOG4105C9M	aspartyl-trna synthetase
CH48_3523	ENOG4108TIT	dATP pyrophosphohydrolase
CH48_3524	ENOG4105CDY	transcriptional regulatory protein
CH48_3525	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CH48_3526	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CH48_3527	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CH48_3528	ENOG4105DUX	Transporter
CH48_3529	ENOG4105FAV	ABC, transporter
CH48_353	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH48_3530	ENOG4105FDK	ABC transporter
CH48_3531	ENOG4105NXV	High-affinity zinc uptake system protein
CH48_3532	ENOG4105DR5	peptidase
CH48_3533	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
CH48_3535	ENOG4105D5G	Transposase
CH48_3536	ENOG4105CA9	Pyruvate kinase
CH48_3537	ENOG4106KNT	transcriptional regulator
CH48_3538	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CH48_3539	ENOG4108UHU	Aldolase
CH48_3540	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
CH48_3542	ENOG4105M4H	endoribonuclease L-psp
CH48_3543	ENOG4105DVT	helicase
CH48_3544	ENOG41072GX	Peptidase M22 Glycoprotease
CH48_3545	ENOG4105Y4Z	Outer Membrane Lipoprotein
CH48_3546	ENOG4105CEY	Amp-dependent synthetase and ligase
CH48_3547	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CH48_3548	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CH48_3549	ENOG4107QMS	site-determining protein
CH48_355	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CH48_3550	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CH48_3552	ENOG4105VNG	YcgL domain-containing protein
CH48_3553	ENOG4105CVE	Lytic murein transglycosylase
CH48_3554	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CH48_3555	ENOG4108ZZ3	UPF0260 protein
CH48_356	ENOG4106WZ1	flagella biosynthesis regulator
CH48_3560	ENOG4105D64	Mechanosensitive ion channel
CH48_3561	ENOG4108SHQ	Glutathione S-transferase
CH48_3566	ENOG4105WT8	Protein of unknown function (DUF1480)
CH48_357	ENOG4105F4P	)-transporter
CH48_3574	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CH48_3576	ENOG4105DY2	Paraquat-inducible protein b
CH48_3577	ENOG4105H2K	paraquat-inducible protein a
CH48_3578	ENOG4108ZGC	gaf domain protein
CH48_358	ENOG4105D6F	Phosphatase
CH48_3580	ENOG4105CN1	protease
CH48_3581	ENOG4105D0M	Protease HtpX homolog
CH48_3582	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CH48_3583	ENOG4105CAZ	oligogalacturonide lyase
CH48_3585	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CH48_3586	ENOG4108ETY	sodium dicarboxylate symporter
CH48_3587	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
CH48_3588	ENOG4108PU9	oligogalacturonate-specific porin
CH48_3589	ENOG4105WEM	extracellular solute-binding protein
CH48_359	ENOG4105ETE	Transcriptional regulator (LacI family
CH48_3590	ENOG4108IJ9	(ABC) transporter
CH48_3591	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
CH48_3592	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
CH48_3593	ENOG41061NF	Pectate lyase
CH48_3594	ENOG4105CHR	reductase
CH48_3595	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CH48_3596	ENOG4105M5J	Cupin 2, conserved barrel domain protein
CH48_3597	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
CH48_3598	ENOG4107PN8	YfeABCD locus regulator
CH48_3599	ENOG4105CYC	Transferase
CH48_3600	ENOG4105DEQ	transcriptional regulator
CH48_3601	ENOG4108M7F	enoyl-CoA hydratase isomerase
CH48_3602	ENOG4105DJT	lAO AO transport system ATPase
CH48_3603	ENOG4105D5P	Methylmalonyl-coA mutase
CH48_3604	ENOG4105FGM	Fructosamine kinase
CH48_3605	ENOG4105CC5	ABC transporter
CH48_3606	ENOG4105CC5	ABC transporter
CH48_3607	ENOG4105DIK	(ABC) transporter
CH48_3608	ENOG4105DSE	periplasmic solute binding protein
CH48_3609	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CH48_361	ENOG4105CK1	PTS System
CH48_3610	ENOG41082NP	Multiple antibiotic resistance
CH48_3615	ENOG4108UQV	Membrane
CH48_3616	ENOG41087WU	
CH48_3617	ENOG4105C22	threonyL-tRNA synthetase
CH48_3618	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CH48_3619	ENOG41082NX	50s ribosomal protein l35
CH48_362	ENOG4105CS2	ec 3.2.1.21
CH48_3620	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CH48_3621	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CH48_3623	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CH48_3624	ENOG4105YB8	TM2 domain containing protein
CH48_3626	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
CH48_3627	ENOG4108V06	Glutathione peroxidase
CH48_3628	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
CH48_3629	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CH48_363	ENOG4105VCP	PTS System
CH48_3630	ENOG4105CKK	Glycosyl transferase, family 2
CH48_3631	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CH48_3632	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CH48_3633	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CH48_3634	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
CH48_3635	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
CH48_3636	ENOG4108QBX	(LipO)protein
CH48_3637	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
CH48_3639	ENOG4107R4I	Periplasmic binding protein
CH48_3640	ENOG4106QJH	hemin transport protein
CH48_3641	ENOG4107ENK	receptor
CH48_3642	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CH48_3643	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CH48_3645	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CH48_3646	ENOG4105IPI	Membrane
CH48_3647	ENOG4105CQB	FAD linked oxidase domain protein
CH48_3649	ENOG4105KA0	thioesterase Superfamily protein
CH48_3650	ENOG4108Z4V	iron-sulfur cluster assembly
CH48_3651	ENOG4105DIW	FeS assembly protein SUFB
CH48_3652	ENOG4105C3K	feS assembly ATPase SufC
CH48_3653	ENOG4105JRK	feS assembly protein SufD
CH48_3655	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CH48_3656	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CH48_3657	ENOG4105KMX	major outer membrane lipoprotein
CH48_3658	ENOG4105CA9	Pyruvate kinase
CH48_366	ENOG4105BZU	Histidine kinase
CH48_3662	ENOG4107QI1	Mate efflux family protein
CH48_3663	ENOG4108R6K	riboflavin synthase, subunit alpha
CH48_3664	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CH48_3665	ENOG4105CZQ	inner membrane transport protein YdhC
CH48_3666	ENOG4105F52	Transcriptional regulator
CH48_3667	ENOG4105ETE	Transcriptional regulator (LacI family
CH48_3669	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CH48_367	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CH48_3670	ENOG4105K4H	Nlp p60 protein
CH48_3671	ENOG4105M2J	Glutaredoxin
CH48_3672	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CH48_3673	ENOG4108UYE	Lactoylglutathione lyase
CH48_3674	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CH48_3675	ENOG4108WUH	Transcriptional regulator, TetR family
CH48_3676	ENOG4105DIJ	Phosphoethanolamine transferase
CH48_3677	ENOG4105XZD	Fe-S protein
CH48_3678	ENOG4107RGM	aldo keto reductase
CH48_3679	ENOG4105DSW	Fusaric acid resistance protein
CH48_368	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CH48_3680	ENOG4105Y49	secretion protein, HlyD family
CH48_3682	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
CH48_3683	ENOG4108XTF	Outer Membrane Lipoprotein
CH48_3685	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CH48_3686	ENOG410642K	Lysozyme inhibitor
CH48_3687	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CH48_3688	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CH48_369	ENOG4105MH2	YfcL protein
CH48_3690	ENOG4108K3A	Glutathione S-transferase
CH48_3691	ENOG4108ZR5	Conserved Protein
CH48_3692	ENOG41069YE	inner membrane protein yohC
CH48_3694	ENOG4105DUX	Transporter
CH48_3695	ENOG4105DUM	transcriptional regulator, lysR family
CH48_3699	ENOG4108JQ2	peptide transport system atp-binding protein
CH48_370	ENOG4108BPE	-transporting atpase
CH48_3700	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
CH48_3701	ENOG4108EU3	peptide transport system, permease
CH48_3702	ENOG4108I5W	peptide transport system, permease protein
CH48_3703	ENOG4108HIY	periplasmic
CH48_3704	ENOG4106DF6	pertussis toxin subunit 1
CH48_3706	ENOG4105E51	psp operon transcriptional activator
CH48_3707	ENOG41087YS	Phage shock protein A
CH48_3708	ENOG4105YYT	phage shock protein B
CH48_3709	ENOG4105FM1	phage shock protein C
CH48_371	ENOG4105EJ9	Membrane
CH48_3711	ENOG4105CM6	amino acid regulated cytosolic protein
CH48_3712	ENOG4106K28	UPF0283 membrane protein
CH48_3716	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CH48_3717	ENOG4105KXI	murein peptide amidase A
CH48_3718	ENOG4107S8C	mandelate racemase muconate lactonizing
CH48_3719	ENOG4107QSI	ABC, transporter
CH48_372	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
CH48_3720	ENOG4107RX3	Mg2 transporter protein cora family protein
CH48_3721	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CH48_3722	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
CH48_3723	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CH48_3725	ENOG4105KT7	mgtC SapB transporter
CH48_3727	ENOG4105C5I	Dehydrogenase
CH48_3728	ENOG4107H52	Dicarboxylate transport
CH48_3729	ENOG410689M	(LipO)protein
CH48_373	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CH48_3730	ENOG4105WXT	Conserved Protein
CH48_3731	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CH48_3732	ENOG4105CQ7	ATP-dependent helicase
CH48_3735	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
CH48_3737	ENOG4105CTD	carboxy-peptidase
CH48_3738	ENOG4105JJR	Histidine kinase
CH48_3739	ENOG4107EXC	regulatoR
CH48_374	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CH48_3741	ENOG4105D5Q	Arginine ornithine antiporter
CH48_3742	ENOG4105C5D	exported protein
CH48_3743	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CH48_3744	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CH48_3745	ENOG4105Q9Y	Universal stress protein
CH48_3746	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CH48_3747	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CH48_3750	ENOG4108S5C	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity)
CH48_3751	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CH48_3753	ENOG4108RVA	ribokinase
CH48_3755	ENOG4105EDR	glucose galactose transporter
CH48_3757	ENOG4105PAD	Hydrolase
CH48_3758	ENOG4105M71	acetolactate synthase 1 regulatory subunit
CH48_3759	ENOG4105C7K	acetolactate synthase
CH48_3761	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CH48_3766	ENOG4105CXY	transporter
CH48_3768	ENOG4105ETE	Transcriptional regulator (LacI family
CH48_3769	ENOG4105FYV	Amp nucleosidase
CH48_377	ENOG4108DG9	Smr protein MutS2
CH48_3770	ENOG4105D13	transposase
CH48_3772	ENOG4107R3N	Filamentation induced by cAMP protein fic
CH48_3776	ENOG4106V2I	dimethylaminohydrolase
CH48_3777	ENOG4105E89	ABC transporter
CH48_3778	ENOG4105DSP	amino acid AbC transporter
CH48_378	ENOG4108BY2	phosphohistidine phosphatase
CH48_3780	ENOG4108RYR	transcriptional regulator AsnC family
CH48_3785	ENOG4105CYM	Glutathione S-transferase
CH48_379	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CH48_3792	ENOG4105GVR	general secretion pathway protein D
CH48_3792	ENOG4105GVR	general secretion pathway protein D
CH48_38	ENOG4105NAC	(LipO)protein
CH48_380	ENOG4105CHU	acetyl-coa acetyltransferase
CH48_381	ENOG4105KZW	UPF0381 protein
CH48_3817	ENOG4105TDT	uncharacterized protein yahO
CH48_3818	ENOG4105EMU	Dehydrogenase
CH48_3819	ENOG4105KK4	UPF0060 membrane protein
CH48_382	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CH48_3821	ENOG4105M5Q	UPF0482 protein
CH48_3822	ENOG4105KBG	Protein of unknown function (DUF1161)
CH48_3825	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CH48_3826	ENOG4105DAG	ROK family
CH48_3827	ENOG4106NZI	LysR family Transcriptional regulator
CH48_3828	ENOG4105D94	Major Facilitator Superfamily
CH48_383	ENOG410903C	(LipO)protein
CH48_3831	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
CH48_3833	ENOG4105C9Q	fumarate hydratase class II
CH48_3834	ENOG4105EIP	mannose-6-phosphate isomerase
CH48_3835	ENOG4106J39	exported protein
CH48_3837	ENOG4107P2S	Transcriptional regulator
CH48_3838	ENOG4105CI1	PTS System
CH48_3839	ENOG4105C87	Aminotransferase class I and II
CH48_384	ENOG4105KWW	Biogenesis protein
CH48_3840	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CH48_3841	ENOG4105DHU	Bile acid
CH48_3842	ENOG4105D9R	oxidoreductase
CH48_3844	ENOG4105CNN	ABC, transporter
CH48_3846	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
CH48_3848	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
CH48_3849	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CH48_385	ENOG4108M1T	Cytochrome c-type biogenesis protein
CH48_3850	ENOG4108JJA	ABC, transporter
CH48_3851	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CH48_3854	ENOG4105CKU	formyltetrahydrofolate synthetase
CH48_3855	ENOG4105M9B	inner membrane protein ydgK
CH48_3856	ENOG4105DGN	Electron transport complex
CH48_3858	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CH48_386	ENOG4107QX9	Thiol disulfide interChange protein
CH48_3861	ENOG4105UEI	Transcriptional Regulator AraC Family
CH48_3862	ENOG4105D6A	Electron transport complex
CH48_3863	ENOG4108UQQ	Electron transport complex
CH48_3865	ENOG4105CSM	endonuclease III
CH48_387	ENOG4105DA4	cytochrome c-type biogenesis protein
CH48_3871	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
CH48_3872	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
CH48_3873	ENOG4105D22	carbon starvation protein
CH48_3874	ENOG4105VCD	cytoplasmic protein
CH48_3875	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CH48_3876	ENOG4105N2W	Transcriptional regulator
CH48_3878	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
CH48_3879	ENOG41061RM	osmotically inducible lipoprotein
CH48_388	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CH48_3881	ENOG4108ZJT	translation initiation factor, Sui1
CH48_3882	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CH48_3883	ENOG4105RC8	Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction
CH48_3884	ENOG4105DKK	Benzoate
CH48_3885	ENOG4108JCI	Transcriptional regulator
CH48_3887	ENOG4105CFV	Tetratricopeptide repeat protein
CH48_3888	ENOG4105Q4A	inner membrane protein yciS
CH48_3889	ENOG4105EYK	Phosphatidylglycerophosphatase B
CH48_389	ENOG4105X3C	heme exporter protein
CH48_3890	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CH48_3892	ENOG4107QM5	aconitate hydratase
CH48_3894	ENOG4107R11	Transcriptional regulator
CH48_3895	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CH48_3896	ENOG4105RKX	Protein of unknown function (DUF2498)
CH48_3897	ENOG4105ERU	peptidase
CH48_3898	ENOG4105UBK	short-chain dehydrogenase reductase
CH48_3899	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CH48_39	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
CH48_390	ENOG41060IM	Heme exporter protein
CH48_3901	ENOG4105FE9	pseudouridine synthase
CH48_3902	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CH48_3903	ENOG4105DB7	PHP domain protein
CH48_3905	ENOG4105DDQ	anthranilate synthase
CH48_3907	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CH48_3908	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CH48_3909	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CH48_391	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CH48_3911	ENOG4105EIF	outer membrane protein W
CH48_3912	ENOG4105PI0	Ferredoxin
CH48_3913	ENOG4108S3I	UPF0259 membrane protein
CH48_3915	ENOG4107835	probably involved in intracellular septation (By similarity)
CH48_3916	ENOG4105NAU	thioesterase Superfamily protein
CH48_3917	ENOG410822N	TonB family
CH48_3918	ENOG4105K9H	YciI-like protein
CH48_3922	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CH48_3923	ENOG4108W5H	UPF0263 protein
CH48_3924	ENOG4108JQ7	(ABC) transporter
CH48_3925	ENOG4105C3U	ABC transporter
CH48_3926	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CH48_3927	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CH48_3928	ENOG4107QSI	ABC, transporter
CH48_3929	ENOG4107QSI	ABC, transporter
CH48_3930	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CH48_3931	ENOG4108EKI	Dehydrogenase
CH48_3932	ENOG4107104	thymidine kinase
CH48_3934	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CH48_3935	ENOG4105I93	response regulator
CH48_3936	ENOG4105D78	K07001 NTE family protein
CH48_3937	ENOG4105K5B	UPF0225 protein
CH48_3938	ENOG4105CIY	formyltetrahydrofolate deformylase
CH48_394	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CH48_3942	ENOG4105SKE	transcriptional Regulator LysR family
CH48_3943	ENOG4105CGK	Exodeoxyribonuclease III
CH48_3944	ENOG4105M6F	mutator MutT protein
CH48_3945	ENOG4105MTM	Protein of unknown function (DUF1496)
CH48_3946	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CH48_3948	ENOG41069NU	Nitroreductase
CH48_3949	ENOG4105D07	Signal peptide peptidase, SppA
CH48_3950	ENOG4105HDK	L-asparaginase
CH48_3951	ENOG4108RWI	nicotinamidase
CH48_3953	ENOG4105VUT	cytoplasmic protein
CH48_3954	ENOG4105E0X	reductase
CH48_3956	ENOG4105DSB	aldose 1-epimerase
CH48_3957	ENOG4105GNX	MltA-interacting MipA family protein
CH48_3958	ENOG4105CYN	Serine protein kinase
CH48_3959	ENOG4106AKX	UPF0229 protein
CH48_396	ENOG4107RA9	decarboxylase
CH48_3962	ENOG4105HEI	LysR family (Transcriptional regulator
CH48_3963	ENOG4105EUB	pirin domain protein
CH48_3964	ENOG4105BZU	Histidine kinase
CH48_3965	ENOG4105CNH	Multidrug resistance protein MdtL
CH48_3966	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CH48_3967	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CH48_3968	ENOG4105ED1	spovr family
CH48_3969	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CH48_397	ENOG4105C5Q	Transcriptional regulator
CH48_3970	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CH48_3971	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CH48_3972	ENOG4106N3A	copper homeostasis protein cutc
CH48_3974	ENOG4106ZCM	YecM protein
CH48_3975	ENOG4105C75	arginyL-tRNA synthetase
CH48_3977	ENOG4105D5M	phosphate starvation-inducible protein
CH48_3979	ENOG4106FQ9	Biofilm PGA synthesis protein PgaD
CH48_398	ENOG4105CPC	Aldo Keto reductase
CH48_3980	ENOG4105CND	Glycosyl transferase, family 2
CH48_3981	ENOG4107BJW	polysaccharide deacetylase
CH48_3982	ENOG4108TUY	outer membrane protein PgaA
CH48_3984	ENOG4105H1N	peptidase, M24
CH48_3985	ENOG4108819	ferric iron reductase
CH48_3986	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CH48_3987	ENOG4105EXG	Transcriptional regulator
CH48_3991	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CH48_3993	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CH48_3996	ENOG4107SJW	iron permease, FTR1
CH48_3999	ENOG4105CSV	Glutaminase
CH48_4	ENOG4105CHR	reductase
CH48_400	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CH48_4000	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
CH48_4001	ENOG4105FB2	class II Aldolase
CH48_4002	ENOG4105G63	Type III effector Hrp-dependent
CH48_4003	ENOG4105MVE	transcriptional regulator
CH48_4004	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CH48_4005	ENOG4108MRH	transcriptional regulatory protein
CH48_4007	ENOG4105C85	amino acid
CH48_401	ENOG4105D9N	nucleoside
CH48_4010	ENOG4106UW1	Major Facilitator superfamily
CH48_4011	ENOG4108HCJ	Hydrolase
CH48_4013	ENOG4105D5G	Transposase
CH48_4014	ENOG4106F2Y	RICIN
CH48_4015	ENOG4108WF3	methyltransferase
CH48_4016	ENOG4105D5G	Transposase
CH48_4025	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CH48_4026	ENOG4105NKT	exported protein
CH48_4027	ENOG4108PNC	copper resistance
CH48_4028	ENOG4105FXM	Copper resistance protein
CH48_4029	ENOG41090A1	ferritin
CH48_4030	ENOG4105MPK	DNA polymerase III subunit theta
CH48_4033	ENOG4105UMD	exodeoxyribonuclease X
CH48_4034	ENOG4105CUG	Oligopeptidase b
CH48_4036	ENOG4105N5Z	UPF0267 protein
CH48_4037	ENOG4105X2V	dna damage-inducible protein
CH48_4038	ENOG4105C1J	atp-dependent rna helicase
CH48_4039	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CH48_4040	ENOG4105X5C	UPF0181 protein
CH48_4042	ENOG4105P8F	nudix hydrolase
CH48_4043	ENOG4105EJQ	L-serine dehydratase
CH48_4046	ENOG4105EE5	Membrane protein terC
CH48_4047	ENOG4108EQA	pts system
CH48_4048	ENOG4105ETZ	PTS System
CH48_4049	ENOG4105F3R	pts system mannose fructose sorbose family iid
CH48_4050	ENOG4108NK4	UPF0266 membrane protein
CH48_4051	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CH48_4053	ENOG4105BZU	Histidine kinase
CH48_4055	ENOG4105DHI	Methyltransferase
CH48_4056	ENOG4105CJN	penicillin-binding protein
CH48_4057	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CH48_4058	ENOG4105VEQ	Cold shock protein
CH48_4059	ENOG410610J	Protein of unknown function (DUF2627) 
CH48_406	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CH48_4060	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
CH48_4061	ENOG4105C85	amino acid
CH48_4064	ENOG41064PC	
CH48_4065	ENOG4105TIK	
CH48_4066	ENOG4105N4N	Protein of unknown function (DUF2766)
CH48_4070	ENOG4105D5Q	Arginine ornithine antiporter
CH48_4072	ENOG4105BZ1	(ABC) transporter
CH48_4078	ENOG4105XXV	Acid-resistance protein
CH48_4079	ENOG4105VTN	Protein of unknown function (DUF1311)
CH48_4081	ENOG4105DWP	Membrane
CH48_4086	ENOG4105KVH	Transcriptional regulator
CH48_4087	ENOG4105ECR	NmrA family
CH48_4088	ENOG4108IQK	o-acetylhomoserine
CH48_4090	ENOG4105KT5	UmuD protein
CH48_4091	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CH48_4092	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CH48_4094	ENOG4106NDP	Transcriptional regulator
CH48_4095	ENOG4108HKT	sucrose-6-phosphate hydrolase
CH48_41	ENOG4105DJ9	glucan biosynthesis protein
CH48_4100	ENOG4108HMX	isocitrate dehydrogenase (NADP)
CH48_4106	ENOG4108HMX	isocitrate dehydrogenase (NADP)
CH48_4107	ENOG4108R99	pseudouridine synthase
CH48_4109	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CH48_411	ENOG4105VRT	cytoplasmic protein
CH48_4110	ENOG41075W9	High frequency lysogenization protein HflD homolog
CH48_4111	ENOG4107QTF	adenylosuccinate lyase
CH48_4113	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CH48_4115	ENOG4105EZE	Cupin 4 family protein
CH48_4117	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CH48_4118	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CH48_4119	ENOG4105D60	lipoprotein releasing system transmembrane protein
CH48_412	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CH48_4121	ENOG4105D60	lipoprotein releasing system transmembrane protein
CH48_4122	ENOG4108JA2	transcriptioN-repair coupling factor
CH48_4123	ENOG4107MBR	17 kDa surface antigen
CH48_4125	ENOG4105CEP	NADH dehydrogenase
CH48_4126	ENOG4105D0Y	UPF0227 protein
CH48_4127	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CH48_4129	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
CH48_4130	ENOG41090DQ	Lipoprotein
CH48_4131	ENOG4105K59	histidine triad (HIT) protein
CH48_4132	ENOG4105F9E	Shikimate 5-dehydrogenase
CH48_4135	ENOG4105C4X	radical SAM domain protein
CH48_4137	ENOG4108JJA	ABC, transporter
CH48_4139	ENOG4105CI1	PTS System
CH48_4140	ENOG4105F8V	Hydrolase, tatD family
CH48_4141	ENOG4107QRG	dna polymerase iii
CH48_4142	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CH48_4143	ENOG4105HHA	aminodeoxychorismate lyase
CH48_4148	ENOG4106CQM	replication
CH48_415	ENOG4105C6T	cysteine synthase
CH48_4150	ENOG4107AVE	This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity)
CH48_416	ENOG4105KZ7	phosphocarrier protein hpr
CH48_4162	ENOG4105CAU	Arsenical resistance protein, ArsH
CH48_4163	ENOG4105KBH	arsR family transcriptional regulator
CH48_417	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CH48_4170	ENOG4105DWP	Membrane
CH48_418	ENOG4105C5Y	PTS System
CH48_4181	ENOG4105EZN	Cobyrinic acid ac-diamide synthase
CH48_4182	ENOG4106JGA	Chromosome (Plasmid) partitioning protein, ParB
CH48_419	ENOG4105E0F	Histidine kinase
CH48_420	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CH48_421	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CH48_4225	ENOG4105D5G	Transposase
CH48_423	ENOG4105C6T	cysteine synthase
CH48_425	ENOG4105ECW	sulfate abc transporter
CH48_426	ENOG4108I5D	sulfate abc transporter
CH48_427	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
CH48_429	ENOG4105QEK	Transcriptional regulator
CH48_430	ENOG4108R66	Conserved Protein
CH48_435	ENOG4105EZR	dyp-type peroxidase family protein
CH48_436	ENOG4105E7K	(LipO)protein
CH48_437	ENOG4105H4F	exported protein
CH48_438	ENOG4108R6G	acetyltransferase
CH48_439	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CH48_440	ENOG4108UPT	UPF0178 protein
CH48_444	ENOG4105C6K	Malic enzyme
CH48_445	ENOG4107VIJ	nudix hydrolase
CH48_446	ENOG4105CUW	cytochrome C-TYPE protein
CH48_447	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
CH48_448	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CH48_449	ENOG41061Q0	Assembly protein for periplasmic nitrate reductase
CH48_45	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CH48_451	ENOG4105WH1	Two component transcriptional regulator luxr family
CH48_453	ENOG4105BZS	acriflavin resistance protein
CH48_457	ENOG4105KUZ	arsenate reductase
CH48_458	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CH48_460	ENOG4105XYK	UPF0370 protein
CH48_464	ENOG4108T1M	outer membrane protein x
CH48_466	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_467	ENOG4105SZK	Rz endopeptidase from lambdoid prophage DLP12
CH48_469	ENOG4106KED	esterase YpfH
CH48_47	ENOG4105VJY	transcriptional regulator
CH48_471	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
CH48_472	ENOG4108VMM	UPF0756 membrane protein
CH48_473	ENOG4105CGZ	zinc metallopeptidase
CH48_474	ENOG4105C8V	SAICAR synthetase
CH48_475	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CH48_476	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CH48_477	ENOG4105RH4	Glycine cleavage system transcriptional repressor
CH48_478	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH48_479	ENOG4105C02	permease
CH48_48	ENOG4107YC3	synthase
CH48_480	ENOG4105ERG	peptidase m48, ste24p
CH48_481	ENOG4105K89	arsenate reductase
CH48_482	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
CH48_483	ENOG4105C2W	permease
CH48_484	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CH48_485	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CH48_486	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CH48_487	ENOG4108MK9	spermidine N(1)-acetyltransferase
CH48_49	ENOG4108W0S	formate-dependent nitrite reductase complex
CH48_491	ENOG4105E2Z	phosphate ABC transporter (Permease
CH48_492	ENOG4105C8U	phosphate abc transporter
CH48_493	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CH48_494	ENOG4105C9X	ppx gppa phosphatase
CH48_496	ENOG4105CJW	magnesium transporter
CH48_497	ENOG4105BZU	Histidine kinase
CH48_498	ENOG4105R8A	Heat shock protein
CH48_5	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CH48_500	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CH48_502	ENOG4105BZS	acriflavin resistance protein
CH48_504	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CH48_505	ENOG4105EB3	Histidine kinase
CH48_506	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CH48_507	ENOG4105KWI	UPF0339 protein
CH48_508	ENOG4105CFP	Peptidase U32
CH48_509	ENOG4107TE5	Lipid kinase
CH48_51	ENOG4107QX9	Thiol disulfide interChange protein
CH48_510	ENOG410787A	Pts system, glucitol sorbitol-specific
CH48_511	ENOG4105DZY	Pts system, glucitol sorbitol-specific
CH48_512	ENOG4105VI0	Pts system, glucitol sorbitol-specific
CH48_513	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
CH48_514	ENOG4105J92	DNA-binding transcriptional activator GutM
CH48_515	ENOG410804X	Transcriptional regulator
CH48_516	ENOG4105C2X	Arabinose 5-phosphate isomerase
CH48_517	ENOG4108ZGU	inhibitor of vertebrate lysozyme
CH48_52	ENOG4105DA4	cytochrome c-type biogenesis protein
CH48_520	ENOG4105DWF	phosphomethylpyrimidine kinase
CH48_527	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CH48_528	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CH48_529	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CH48_53	ENOG4105DVI	reductase, NrfD
CH48_530	ENOG4105VPD	cellular component movement
CH48_533	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CH48_534	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CH48_535	ENOG4105N21	Membrane
CH48_536	ENOG4105CUT	histidyl-tRNA synthetase
CH48_537	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CH48_538	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CH48_54	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CH48_540	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CH48_543	ENOG4108JQB	penicillin-binding protein 1C
CH48_544	ENOG4105DN3	alpha-2-macroglobulin domain protein
CH48_546	ENOG4108MGN	ATP-binding component of a transport system
CH48_547	ENOG4105YYA	enhanced serine sensitivity protein SseB
CH48_549	ENOG4105WVQ	Fe-S assembly protein IscX
CH48_55	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
CH48_550	ENOG4108ZIT	Ferredoxin, 2FE-2S
CH48_551	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CH48_552	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CH48_553	ENOG4108Z4V	iron-sulfur cluster assembly
CH48_554	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CH48_555	ENOG4105C3J	Cysteine desulfurase
CH48_556	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CH48_557	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
CH48_559	ENOG4105D7X	high-affinity nickel-transporter
CH48_56	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
CH48_560	ENOG41065CD	Exported protein
CH48_561	ENOG4105D8G	Major Facilitator superfamily
CH48_562	ENOG4108MN2	Stationary phase inducible protein CsiE
CH48_563	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CH48_564	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CH48_567	ENOG4105RMW	regulation of transcription, DNA-dependent
CH48_568	ENOG4108626	Racemase
CH48_569	ENOG41080QX	K07048 phosphotriesterase-related protein
CH48_570	ENOG4105MUZ	Protein of unknown function DUF2620
CH48_571	ENOG4106M0N	transport system permease protein
CH48_572	ENOG4108YZA	Nitrogen regulatory protein pii
CH48_573	ENOG4105C4K	Nad synthetase
CH48_574	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CH48_575	ENOG4108SKK	alpha helix protein
CH48_576	ENOG4107WP9	Histidine kinase
CH48_579	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CH48_58	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
CH48_580	ENOG4108Z6B	deaminase
CH48_582	ENOG4105HYY	HAD superfamily (Subfamily IF) hydrolase, YfhB
CH48_584	ENOG4106G6Q	Transcriptional regulator
CH48_585	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CH48_586	ENOG4107EFN	gluconate transport system permease 3
CH48_587	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CH48_588	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CH48_589	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CH48_59	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CH48_590	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CH48_591	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CH48_592	ENOG4105C3F	Signal peptidase i
CH48_593	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CH48_595	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
CH48_597	ENOG41069PW	sigma-e factor negative regulatory protein
CH48_599	ENOG4108IYU	L-aspartate oxidase
CH48_6	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CH48_600	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CH48_601	ENOG4105C1J	atp-dependent rna helicase
CH48_602	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_607	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
CH48_608	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CH48_609	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH48_610	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CH48_611	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CH48_612	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CH48_615	ENOG4108Z1B	Cyclase dehydrase
CH48_616	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CH48_617	ENOG4105DFP	Integrase
CH48_62	ENOG4105DR4	Methyltransferase
CH48_621	ENOG4105NI8	Cytosine-specific methyltransferase
CH48_63	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
CH48_630	ENOG410901P	UPF0249 protein
CH48_631	ENOG4105EZV	Transcriptional regulator
CH48_632	ENOG4105VCP	PTS System
CH48_633	ENOG4105CS2	ec 3.2.1.21
CH48_634	ENOG4105CK1	PTS System
CH48_635	ENOG4105VZJ	PTS System
CH48_636	ENOG4105D8V	Glucose sorbosone dehydrogenase
CH48_638	ENOG4105CPC	Aldo Keto reductase
CH48_64	ENOG4105K4P	CoA-binding domain protein
CH48_641	ENOG41086WQ	Protein CrcB homolog
CH48_642	ENOG4107SVH	Potassium channel protein
CH48_643	ENOG4105XXV	Acid-resistance protein
CH48_646	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CH48_647	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CH48_648	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CH48_649	ENOG4108VDS	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CH48_65	ENOG4108Q67	UPF0319 protein
CH48_650	ENOG4105CQM	Urea amidohydrolase subunit alpha
CH48_651	ENOG4105KI2	Urea amidohydrolase subunit beta
CH48_653	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
CH48_655	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CH48_66	ENOG4108Z5K	methylglyoxal synthase
CH48_662	ENOG4105VEQ	Cold shock protein
CH48_665	ENOG4108WMJ	Protein of unknown function (DUF2002)
CH48_666	ENOG4105F9N	Major Facilitator Superfamily
CH48_667	ENOG41075H3	AraC family transcriptional regulator
CH48_67	ENOG41088T4	Helicase IV
CH48_671	ENOG4105TNS	Conserved Protein
CH48_673	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CH48_675	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
CH48_677	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CH48_678	ENOG4108IJ7	Glycine betaine
CH48_679	ENOG4108HQS	Glycine betaine
CH48_68	ENOG410901E	Membrane
CH48_680	ENOG4105GIJ	Glycine betaine
CH48_682	ENOG4108JDX	DNA polymerase iii, epsilon subunit
CH48_683	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CH48_684	ENOG4105D1A	Methyltransferase
CH48_685	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CH48_686	ENOG4105E9H	Lytic Murein transglycosylase
CH48_687	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_688	ENOG4105EQR	Transposase IS116 IS110 IS902
CH48_689	ENOG4107NA1	Endonuclease Exonuclease phosphatase
CH48_69	ENOG4105EM2	membrane
CH48_690	ENOG4105F27	Major Facilitator
CH48_691	ENOG4105HEI	LysR family (Transcriptional regulator
CH48_692	ENOG4105CV8	reductase
CH48_693	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CH48_694	ENOG4105D5G	Transposase
CH48_7	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CH48_70	ENOG4108RZ1	DNA transformation protein
CH48_702	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CH48_704	ENOG4108UMI	ABC transporter, permease
CH48_705	ENOG4105D01	(LipO)protein
CH48_706	ENOG4108R8X	outer membrane lipoprotein
CH48_707	ENOG4108R96	Methyltransferase, YaeB family
CH48_708	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CH48_709	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
CH48_71	ENOG4108ZD2	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity)
CH48_710	ENOG4108YZN	class I peptide chain release factor
CH48_711	ENOG4108VWS	Yaeq family
CH48_712	ENOG4105W1I	UPF0253 protein
CH48_713	ENOG4105M1T	rho-binding antiterminator
CH48_714	ENOG4105N7H	Cytochrome
CH48_715	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CH48_716	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CH48_717	ENOG4105CXN	decarboxylase
CH48_718	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CH48_719	ENOG4105C0B	DNA polymerase III (alpha subunit)
CH48_72	ENOG4105UYK	outer membrane protein a
CH48_720	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CH48_721	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CH48_722	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CH48_724	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CH48_725	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
CH48_727	ENOG4105DZP	Membrane-associated zinc metalloprotease
CH48_728	ENOG4105KNE	Phosphatidate cytidylyltransferase
CH48_729	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CH48_73	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
CH48_730	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CH48_731	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CH48_732	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CH48_733	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CH48_734	ENOG4105CE9	30S ribosomal protein S2
CH48_735	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CH48_736	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CH48_737	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CH48_738	ENOG4108T8E	UPF0325 protein
CH48_739	ENOG4105QDK	Flavodoxin
CH48_74	ENOG4105DAN	ATP-dependent protease
CH48_740	ENOG4105DR9	pseudouridine synthase
CH48_741	ENOG4105WP7	tRNA pseudouridine synthase C
CH48_742	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
CH48_743	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CH48_744	ENOG4105EWT	decarboxylase family
CH48_745	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
CH48_748	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CH48_749	ENOG4105M08	Membrane
CH48_75	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CH48_750	ENOG4105ETT	transcriptional Regulator, LysR family
CH48_751	ENOG4105M5B	(LipO)protein
CH48_752	ENOG4105C9B	Cysteine desulfurase
CH48_753	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CH48_754	ENOG4105CUZ	uba thif-type nad fad binding protein
CH48_755	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CH48_759	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CH48_760	ENOG4107QZM	n-acetylglutamate synthase
CH48_763	ENOG4107QYX	exodeoxyribonuclease v alpha
CH48_764	ENOG4107QKA	exodeoxyribonuclease V beta
CH48_765	ENOG4107QXK	peptidase
CH48_766	ENOG4105DSY	exodeoxyribonuclease V, gamma
CH48_770	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CH48_771	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CH48_772	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
CH48_773	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CH48_774	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
CH48_775	ENOG4105EE5	Membrane protein terC
CH48_776	ENOG4105CPC	Aldo Keto reductase
CH48_777	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
CH48_778	ENOG4105CEY	Amp-dependent synthetase and ligase
CH48_78	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CH48_781	ENOG41060NJ	transcriptional regulator
CH48_782	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CH48_783	ENOG4105F27	Major Facilitator
CH48_784	ENOG4105RQF	LysR family Transcriptional regulator
CH48_785	ENOG4105EJC	lysr family transcriptional regulator
CH48_787	ENOG4105C8Q	Methyl-accepting chemotaxis
CH48_79	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
CH48_792	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CH48_8	ENOG4105VGS	50s ribosomal protein l32
CH48_80	ENOG4108Q2G	(LipO)protein
CH48_800	ENOG4108VAU	general secretion pathway protein G
CH48_801	ENOG4105D7Q	type ii secretion system
CH48_802	ENOG4107QHF	type ii secretion system protein e
CH48_806	ENOG4107B2H	carbonic anhydrase
CH48_807	ENOG4105KVH	Transcriptional regulator
CH48_808	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CH48_81	ENOG4105DY2	Paraquat-inducible protein b
CH48_810	ENOG4105DVC	DnaJ domain protein
CH48_812	ENOG4105BZU	Histidine kinase
CH48_813	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
CH48_816	ENOG4105D5G	Transposase
CH48_817	ENOG4105WJ3	XRE family Transcriptional regulator
CH48_818	ENOG4105RT5	Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation
CH48_82	ENOG4105F1S	paraquat-inducible protein a
CH48_83	ENOG4105C5H	ABC transporter
CH48_831	ENOG4105CRK	lysyL-tRNA synthetase
CH48_832	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CH48_833	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CH48_834	ENOG4105T95	Thiol disulfide interChange protein
CH48_835	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CH48_836	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
CH48_837	ENOG4105CT7	inner membrane cred family protein
CH48_838	ENOG4105EB3	Histidine kinase
CH48_839	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CH48_84	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CH48_841	ENOG4105Y75	tpr repeat protein
CH48_842	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CH48_844	ENOG4108UT2	hemolysin iii
CH48_846	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CH48_849	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CH48_85	ENOG4105QVC	MOSC domain-containing protein
CH48_850	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CH48_851	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CH48_852	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CH48_853	ENOG4105D0A	hydroxylase
CH48_854	ENOG4107RAQ	aminopeptidase
CH48_855	ENOG4105E07	UPF0149 protein
CH48_856	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CH48_857	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CH48_858	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CH48_859	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CH48_86	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
CH48_861	ENOG4105DXN	mazG family
CH48_862	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CH48_863	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CH48_864	ENOG4105BZU	Histidine kinase
CH48_865	ENOG4105C0H	protease
CH48_866	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CH48_867	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CH48_869	ENOG4105EN6	Membrane
CH48_87	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CH48_870	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CH48_872	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CH48_873	ENOG4105DQQ	Major facilitator superfamily MFS_1
CH48_874	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
CH48_876	ENOG4105J76	Periplasmic binding protein
CH48_877	ENOG4105E0A	ABC, transporter
CH48_878	ENOG4105BZ4	penicillin-binding protein
CH48_879	ENOG4105CQ7	ATP-dependent helicase
CH48_88	ENOG4105CD8	aminopeptidase N
CH48_880	ENOG4107XID	2'-5' rna ligase
CH48_881	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CH48_882	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH48_884	ENOG4105DJ0	Poly(A) Polymerase
CH48_885	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH48_886	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CH48_887	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CH48_888	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CH48_889	ENOG4107BJW	polysaccharide deacetylase
CH48_89	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CH48_890	ENOG4105E3A	(ABC) transporter
CH48_891	ENOG4105DA5	(ABC) transporter
CH48_893	ENOG41077A9	carbonic anhydrase
CH48_894	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CH48_895	ENOG4105E3B	Multicopper oxidase
CH48_896	ENOG4108ZRK	uncharacterized protein yacC
CH48_897	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CH48_898	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CH48_9	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CH48_90	ENOG4105C5S	asparaginyl-tRNA synthetase
CH48_900	ENOG4105RPH	Inner membrane protein YddG
CH48_901	ENOG4108ZIG	UPF0231 protein
CH48_902	ENOG4107QIJ	Aconitate hydratase 2
CH48_903	ENOG4107RNH	Outer membrane receptor FepA
CH48_904	ENOG4105ECQ	AraC Family Transcriptional Regulator
CH48_906	ENOG4107QN2	dihydrolipoyl dehydrogenase
CH48_907	ENOG4107QSN	dihydrolipoamide acetyltransferase
CH48_908	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CH48_909	ENOG41073TP	transcriptional regulator
CH48_910	ENOG4105C85	amino acid
CH48_911	ENOG4106A72	regulatory protein AmpE
CH48_913	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CH48_914	ENOG4108ZUW	Major pilin subunit
CH48_915	ENOG4107QHF	type ii secretion system protein e
CH48_916	ENOG4105D7Q	type ii secretion system
CH48_917	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CH48_918	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CH48_92	ENOG4105CGF	Aromatic amino acid aminotransferase
CH48_920	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CH48_921	ENOG4105M6F	mutator MutT protein
CH48_922	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CH48_923	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
CH48_926	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CH48_927	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CH48_928	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CH48_93	ENOG4105BZU	Histidine kinase
CH48_930	ENOG4105DFU	Cell wall formation (By similarity)
CH48_931	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CH48_932	ENOG4105CNI	cell division protein FtsW
CH48_934	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CH48_935	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CH48_936	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CH48_937	ENOG4105CJN	penicillin-binding protein
CH48_938	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CH48_939	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CH48_94	ENOG4105C5X	domain protein
CH48_940	ENOG4108V6E	Cell division protein mraZ
CH48_942	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
CH48_943	ENOG4108ZP8	Acetolactate synthase small subunit
CH48_944	ENOG4105C7K	acetolactate synthase
CH48_945	ENOG4108IQE	Amp-dependent synthetase and ligase
CH48_946	ENOG41064T2	transcriptional regulator, lysR family
CH48_948	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CH48_949	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CH48_95	ENOG4105EAQ	(twin-arginine translocation) pathway signal
CH48_950	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CH48_953	ENOG4105C0F	tryptophanase EC 4.1.99.1
CH48_954	ENOG4105CIC	tryptophan-specific transport protein
CH48_956	ENOG4105S8Q	sugar efflux transporter
CH48_957	ENOG4105C6N	Formate acetyltransferase
CH48_958	ENOG4105F1A	Pyruvate formate-lyase
CH48_959	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
CH48_96	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CH48_962	ENOG4105DP9	ABC transporter
CH48_963	ENOG4106SMU	thiamine transporter membrane protein
CH48_964	ENOG4108KF1	Membrane
CH48_966	ENOG4105CQ2	DNA polymerase
CH48_967	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CH48_968	ENOG4105TNG	K13735 adhesin invasin
CH48_969	ENOG4105D3G	Pseudouridine synthase
CH48_97	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
CH48_970	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CH48_971	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CH48_972	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CH48_974	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CH48_975	ENOG4105NWN	ApaG protein
CH48_976	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CH48_977	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CH48_978	ENOG4107XM3	UPF0442 protein
CH48_979	ENOG4105DWK	Membrane
CH48_98	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
CH48_980	ENOG4105N14	lysine exporter protein LysE YggA
CH48_981	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CH48_982	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CH48_983	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CH48_984	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CH48_985	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CH48_986	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CH48_987	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CH48_988	ENOG4105DTN	riboflavin biosynthesis protein ribF
CH48_989	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CH48_99	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
CH48_990	ENOG41063Z6	transcriptional regulator, lysR family
CH48_991	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CH48_992	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CH48_993	ENOG4105CFG	Acts as a chaperone (By similarity)
CH48_994	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CH48_998	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CH48_999	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)