locus-tag	class	description
FORC066_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC066_0002	COG0592	DNA-directed DNA polymerase activity
FORC066_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC066_0004	COG0187	DNA topoisomerase II activity
FORC066_0005	COG0561	phosphatase activity
FORC066_0006	COG1940	carbohydrate kinase activity
FORC066_0007	COG2423	ornithine cyclodeaminase activity
FORC066_0008	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC066_0009	COG0823	Involved in the tonB-independent uptake of proteins
FORC066_0010	COG5645	(Lipo)protein
FORC066_0013	COG0569	domain protein
FORC066_0013	COG2985	domain, Protein
FORC066_0014	COG3977	Valine--pyruvate aminotransferase
FORC066_0015	COG0366	Alpha amylase catalytic
FORC066_0016	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC066_0019	COG2885	chlorophyll binding
FORC066_0023	COG2818	Glycosylase
FORC066_0024	COG0752	glycyl-tRNA synthetase alpha subunit
FORC066_0025	COG0751	glycine-tRNA ligase activity
FORC066_0027	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_0027	COG2213	PTS system mannitol-specific
FORC066_0028	COG0246	Mannitol dehydrogenase
FORC066_0029	COG3722	fumarate hydratase activity
FORC066_0031	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC066_0035	COG2258	MOSC domain
FORC066_0036	COG0840	transmembrane signaling receptor activity
FORC066_0037	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC066_0038	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC066_0039	COG0243	molybdopterin cofactor binding
FORC066_0039	COG3383	formate dehydrogenase (NAD+) activity
FORC066_0040	COG3383	formate dehydrogenase (NAD+) activity
FORC066_0040	COG0243	molybdopterin cofactor binding
FORC066_0041	COG0437	4 iron, 4 sulfur cluster binding
FORC066_0042	COG2864	formate dehydrogenase
FORC066_0043	COG3058	Necessary for formate dehydrogenase activity
FORC066_0044	COG1921	L-seryl-tRNASec selenium transferase activity
FORC066_0045	COG3276	selenocysteine insertion sequence binding
FORC066_0047	COG3274	enterobacterial common antigen metabolic process
FORC066_0051	COG3121	Chaperone
FORC066_0052	COG1070	Carbohydrate kinase
FORC066_0053	COG2115	Belongs to the xylose isomerase family
FORC066_0054	COG4213	ABC transporter substrate-binding protein
FORC066_0056	COG4214	carbohydrate transport
FORC066_0057	COG1609	Transcriptional regulator
FORC066_0057	COG2207	Transcriptional regulator
FORC066_0059	COG1609	Transcriptional regulator
FORC066_0060	COG1940	carbohydrate kinase activity
FORC066_0061	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC066_0062	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC066_0063	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC066_0065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC066_0068	COG2723	6-phospho-beta-galactosidase activity
FORC066_0069	COG1482	cell wall glycoprotein biosynthetic process
FORC066_0076	COG4974	Belongs to the 'phage' integrase family
FORC066_0078	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC066_0079	COG2986	histidine ammonia-lyase
FORC066_0082	COG1764	response to oxidative stress
FORC066_0083	COG2194	sulfuric ester hydrolase activity
FORC066_0084	COG2197	response regulator
FORC066_0085	COG3851	Histidine kinase
FORC066_0087	COG3210	domain, Protein
FORC066_0088	COG2831	hemolysin activation secretion protein
FORC066_0089	COG3210	domain, Protein
FORC066_0091	COG0747	negative chemotaxis
FORC066_0092	COG0601	transmembrane transport
FORC066_0093	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC066_0094	COG0444	Belongs to the ABC transporter superfamily
FORC066_0095	COG4608	Belongs to the ABC transporter superfamily
FORC066_0096	COG2194	sulfuric ester hydrolase activity
FORC066_0100	COG1192	Involved in chromosome partitioning
FORC066_0101	COG1215	transferase activity, transferring glycosyl groups
FORC066_0102	COG1215	transferase activity, transferring glycosyl groups
FORC066_0103	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC066_0104	COG3118	belongs to the thioredoxin family
FORC066_0104	COG0457	Tetratricopeptide repeat
FORC066_0105	COG2200	EAL domain
FORC066_0105	COG2199	diguanylate cyclase activity
FORC066_0106	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC066_0109	COG1301	dicarboxylic acid transport
FORC066_0110	COG0612	Peptidase, M16
FORC066_0112	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC066_0113	COG1942	4-Oxalocrotonate Tautomerase
FORC066_0114	COG2200	EAL domain
FORC066_0115	COG2982	Protein involved in outer membrane biogenesis
FORC066_0116	COG2134	cdp-diacylglycerol pyrophosphatase
FORC066_0117	COG1295	ribonuclease BN
FORC066_0120	COG1396	sequence-specific DNA binding
FORC066_0122	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC066_0131	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC066_0141	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC066_0142	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC066_0144	COG0742	ribosomal rna small subunit methyltransferase
FORC066_0147	COG0589	response to stress
FORC066_0150	COG0306	phosphate transporter
FORC066_0151	COG2081	HI0933 family
FORC066_0167	COG1301	dicarboxylic acid transport
FORC066_0170	COG3799	methylaspartate ammonia-lyase activity
FORC066_0171	COG4865	methylaspartate mutase activity
FORC066_0173	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC066_0176	COG1648	precorrin-2 dehydrogenase activity
FORC066_0176	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC066_0178	COG0583	DNA-binding transcription factor activity
FORC066_0179	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC066_0179	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC066_0181	COG0561	phosphatase activity
FORC066_0183	COG0583	DNA-binding transcription factor activity
FORC066_0184	COG2814	Major facilitator Superfamily
FORC066_0187	COG3718	enzyme involved in inositol metabolism
FORC066_0189	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC066_0191	COG0673	inositol 2-dehydrogenase activity
FORC066_0192	COG1082	Xylose isomerase domain protein TIM barrel
FORC066_0193	COG1247	-acetyltransferase
FORC066_0194	COG1741	Belongs to the pirin family
FORC066_0195	COG1609	Transcriptional regulator
FORC066_0196	COG2610	gluconate transmembrane transporter activity
FORC066_0197	COG3265	gluconokinase activity
FORC066_0199	COG2095	MarC family integral membrane protein
FORC066_0200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC066_0204	COG3275	phosphorelay sensor kinase activity
FORC066_0205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC066_0206	COG1523	belongs to the glycosyl hydrolase 13 family
FORC066_0208	COG0297	glycogen (starch) synthase activity
FORC066_0209	COG0058	SHG alpha-glucan phosphorylase activity
FORC066_0210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC066_0213	COG1349	DNA-binding transcription factor activity
FORC066_0214	COG0705	Rhomboid family
FORC066_0217	COG2909	trisaccharide binding
FORC066_0218	COG0058	SHG alpha-glucan phosphorylase activity
FORC066_0219	COG1640	4-alpha-glucanotransferase
FORC066_0220	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC066_0220	COG0316	Belongs to the HesB IscA family
FORC066_0222	COG0596	Alpha beta hydrolase
FORC066_0225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC066_0226	COG1918	ferrous iron import across plasma membrane
FORC066_0227	COG2183	response to ionizing radiation
FORC066_0228	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC066_0231	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORC066_0233	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC066_0234	COG1011	Hydrolase
FORC066_0237	COG0494	nUDIX hydrolase
FORC066_0238	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC066_0243	COG4796	Type ii and iii secretion system protein
FORC066_0244	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC066_0248	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC066_0250	COG0180	Tryptophanyl-tRNA synthetase
FORC066_0251	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC066_0251	COG1648	precorrin-2 dehydrogenase activity
FORC066_0254	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC066_0256	COG0402	S-adenosylhomocysteine deaminase activity
FORC066_0257	COG0738	Major facilitator superfamily
FORC066_0259	COG1486	melibiose metabolic process
FORC066_0260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC066_0261	COG0433	COG0433 Predicted ATPase
FORC066_0264	COG1289	transmembrane transporter activity
FORC066_0266	COG1765	OsmC-like protein
FORC066_0267	COG3954	Phosphoribulokinase
FORC066_0268	COG3089	Belongs to the UPF0270 family
FORC066_0269	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC066_0272	COG4521	taurine ABC transporter
FORC066_0274	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC066_0275	COG2175	clavaminate synthase activity
FORC066_0277	COG1216	Glycosyl transferase, family 2
FORC066_0278	COG0488	(ABC) transporter
FORC066_0279	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC066_0281	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FORC066_0282	COG1047	Peptidyl-prolyl cis-trans
FORC066_0283	COG2900	Belongs to the SlyX family
FORC066_0284	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC066_0285	COG2964	Protein conserved in bacteria
FORC066_0286	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC066_0287	COG2923	Belongs to the DsrF TusC family
FORC066_0288	COG2168	tRNA wobble position uridine thiolation
FORC066_0289	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC066_0290	COG0049	tRNA binding
FORC066_0292	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC066_0296	COG0051	transcription antitermination factor activity, RNA binding
FORC066_0297	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC066_0298	COG0088	Forms part of the polypeptide exit tunnel
FORC066_0299	COG0089	rRNA binding
FORC066_0300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC066_0301	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC066_0302	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORC066_0303	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC066_0304	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC066_0305	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC066_0306	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC066_0307	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC066_0308	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC066_0309	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC066_0310	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC066_0312	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC066_0313	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC066_0315	COG1841	ribosomal large subunit assembly
FORC066_0316	COG0200	Binds to the 23S rRNA
FORC066_0317	COG0201	protein transport
FORC066_0319	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC066_0321	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC066_0322	COG0202	RNA polymerase activity
FORC066_0323	COG0203	ribosomal protein L17
FORC066_0325	COG0789	Transcriptional regulator
FORC066_0326	COG3036	rescue of stalled ribosome
FORC066_0327	COG1970	mechanosensitive ion channel activity
FORC066_0329	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC066_0329	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC066_0331	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC066_0332	COG0242	peptide deformylase activity
FORC066_0333	COG0758	DNA mediated transformation
FORC066_0335	COG0551	DNA topoisomerase type I activity
FORC066_0336	COG0009	L-threonylcarbamoyladenylate synthase
FORC066_0337	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC066_0338	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC066_0340	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC066_0341	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC066_0343	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FORC066_0344	COG1414	Transcriptional regulator
FORC066_0350	COG0527	aspartate kinase activity
FORC066_0351	COG0166	Belongs to the GPI family
FORC066_0352	COG3223	Belongs to the PsiE family
FORC066_0353	COG3833	ABC-type maltose transport systems, permease component
FORC066_0354	COG1175	transmembrane transport
FORC066_0355	COG2182	Extracellular solute-binding protein
FORC066_0357	COG4580	involved in the transport of maltose and maltodextrins
FORC066_0359	COG3161	chorismate lyase activity
FORC066_0360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC066_0361	COG2937	Belongs to the GPAT DAPAT family
FORC066_0362	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC066_0363	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC066_0364	COG3237	CsbD-like
FORC066_0365	COG0735	belongs to the Fur family
FORC066_0366	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC066_0372	COG1448	Aminotransferase
FORC066_0373	COG2315	Protein conserved in bacteria
FORC066_0374	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC066_0377	COG2252	PERMEase
FORC066_0378	COG0025	NhaP-type Na H and K H
FORC066_0379	COG0583	DNA-binding transcription factor activity
FORC066_0380	COG1380	Effector of murein hydrolase LrgA
FORC066_0382	COG1126	abc transporter atp-binding protein
FORC066_0383	COG0765	amino acid transport
FORC066_0384	COG4597	amino acid ABC transporter
FORC066_0385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_0387	COG1560	Kdo2-lipid A biosynthetic process
FORC066_0388	COG0471	metal ion transport
FORC066_0389	COG1278	Cold shock
FORC066_0390	COG1278	Cold shock
FORC066_0391	COG1278	Cold shock
FORC066_0392	COG3133	Outer membrane lipoprotein
FORC066_0394	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC066_0395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC066_0396	COG2264	protein methyltransferase activity
FORC066_0397	COG4145	pantothenate transmembrane transporter activity
FORC066_0398	COG3924	membrane
FORC066_0399	COG0439	Biotin carboxylase
FORC066_0400	COG0511	ligase activity, forming carbon-carbon bonds
FORC066_0401	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC066_0402	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FORC066_0404	COG0604	alcohol dehydrogenase
FORC066_0405	COG2200	EAL domain
FORC066_0405	COG2199	diguanylate cyclase activity
FORC066_0406	COG1077	Cell shape determining protein MreB Mrl
FORC066_0407	COG1792	Involved in formation and maintenance of cell shape
FORC066_0408	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC066_0409	COG0424	maF-like protein
FORC066_0410	COG1530	ribonuclease E activity
FORC066_0411	COG3164	Protein of unknown function
FORC066_0412	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC066_0413	COG0312	modulator of DNA gyrase
FORC066_0414	COG0583	DNA-binding transcription factor activity
FORC066_0416	COG1566	PFAM secretion protein HlyD family protein
FORC066_0417	COG1289	transmembrane transporter activity
FORC066_0420	COG2732	(Barnase) inhibitor
FORC066_0421	COG3028	Belongs to the UPF0307 family
FORC066_0422	COG0312	modulator of DNA gyrase
FORC066_0423	COG3783	Cytochrome b(562)
FORC066_0424	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC066_0430	COG3964	amidohydrolase
FORC066_0433	COG2706	6-phosphogluconolactonase activity
FORC066_0434	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_0434	COG3711	transcriptional antiterminator
FORC066_0437	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC066_0440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_0440	COG1263	PTS System
FORC066_0441	COG0366	Alpha amylase catalytic
FORC066_0446	COG2308	Evidence 4 Homologs of previously reported genes of
FORC066_0449	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FORC066_0450	COG0540	Belongs to the ATCase OTCase family
FORC066_0453	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_0454	COG1660	Displays ATPase and GTPase activities
FORC066_0457	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORC066_0459	COG1137	ATPase activity
FORC066_0460	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC066_0461	COG3117	lipopolysaccharide transmembrane transporter activity
FORC066_0462	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC066_0463	COG0517	IMP dehydrogenase activity
FORC066_0463	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC066_0464	COG0530	calcium, potassium:sodium antiporter activity
FORC066_0466	COG1127	ABC transporter
FORC066_0467	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC066_0468	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC066_0469	COG2854	intermembrane phospholipid transfer
FORC066_0470	COG3113	response to antibiotic
FORC066_0471	COG5007	Belongs to the BolA IbaG family
FORC066_0472	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORC066_0473	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC066_0474	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC066_0475	COG3105	Protein conserved in bacteria
FORC066_0476	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC066_0477	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC066_0478	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC066_0480	COG0625	glutathione transferase activity
FORC066_0481	COG2969	positive regulation of protein catabolic process
FORC066_0483	COG0493	'glutamate synthase
FORC066_0484	COG0067	glutamate synthase
FORC066_0484	COG0069	glutamate synthase activity
FORC066_0484	COG0070	glutamate synthase
FORC066_0485	COG1242	4 iron, 4 sulfur cluster binding
FORC066_0486	COG5002	protein histidine kinase activity
FORC066_0486	COG0784	Response regulator, receiver
FORC066_0486	COG2198	Histidine kinase
FORC066_0487	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC066_0488	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC066_0489	COG2823	Periplasmic or secreted lipoprotein
FORC066_0490	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC066_0491	COG0792	nuclease activity
FORC066_0493	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC066_0496	COG0667	Aldo Keto reductase
FORC066_0497	COG1064	alcohol dehydrogenase
FORC066_0498	COG1741	Belongs to the pirin family
FORC066_0499	COG0583	DNA-binding transcription factor activity
FORC066_0500	COG0435	Glutathione S-transferase
FORC066_0501	COG2259	Doxx family
FORC066_0503	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FORC066_0504	COG4575	ribosome binding
FORC066_0507	COG0586	Pfam SNARE associated Golgi protein
FORC066_0510	COG2271	Major facilitator Superfamily
FORC066_0511	COG1904	glucuronate isomerase
FORC066_0512	COG0246	Mannitol dehydrogenase
FORC066_0513	COG2721	sulfolactate sulfo-lyase activity
FORC066_0515	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC066_0516	COG0861	Integral membrane protein TerC family
FORC066_0517	COG0673	inositol 2-dehydrogenase activity
FORC066_0518	COG1451	nucleotide metabolic process
FORC066_0520	COG2813	Specifically methylates the guanine in position
FORC066_0521	COG1902	pentaerythritol trinitrate reductase activity
FORC066_0521	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC066_0523	COG3247	response to pH
FORC066_0526	COG0076	glutamate decarboxylase activity
FORC066_0527	COG0531	amino acid
FORC066_0529	COG1263	PTS System
FORC066_0529	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_0531	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC066_0534	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC066_0536	COG3876	Protein conserved in bacteria
FORC066_0539	COG0358	DNA primase activity
FORC066_0540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC066_0541	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC066_0542	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FORC066_0543	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC066_0544	COG1968	undecaprenyl-diphosphatase activity
FORC066_0545	COG0617	tRNA 3'-terminal CCA addition
FORC066_0546	COG4991	sh3 domain protein
FORC066_0547	COG3025	triphosphatase activity
FORC066_0548	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC066_0549	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FORC066_0549	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FORC066_0550	COG0531	amino acid
FORC066_0552	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC066_0553	COG3384	dioxygenase
FORC066_0554	COG0754	glutathionylspermidine amidase activity
FORC066_0555	COG5463	Belongs to the UPF0441 family
FORC066_0556	COG1538	Outer membrane efflux protein
FORC066_0559	COG0494	nUDIX hydrolase
FORC066_0560	COG3151	Protein conserved in bacteria
FORC066_0561	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FORC066_0562	COG3150	esterase
FORC066_0565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC066_0566	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC066_0567	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC066_0569	COG2132	Multicopper oxidase
FORC066_0571	COG0656	L-ascorbic acid biosynthetic process
FORC066_0572	COG1979	alcohol dehydrogenase
FORC066_0574	COG2207	Transcriptional regulator
FORC066_0575	COG0586	Pfam SNARE associated Golgi protein
FORC066_0578	COG0848	biopolymer transport protein
FORC066_0588	COG4964	Belongs to the GSP D family
FORC066_0594	COG3145	DNA-N1-methyladenine dioxygenase activity
FORC066_0595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC066_0596	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_0601	COG4774	siderophore transport
FORC066_0604	COG1120	ATPase activity
FORC066_0605	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC066_0606	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC066_0607	COG4592	Periplasmic binding protein
FORC066_0609	COG2271	Major facilitator Superfamily
FORC066_0610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC066_0611	COG0840	transmembrane signaling receptor activity
FORC066_0615	COG3133	Outer membrane lipoprotein
FORC066_0617	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FORC066_0620	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FORC066_0622	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FORC066_0624	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FORC066_0625	COG1773	rubredoxin
FORC066_0627	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FORC066_0628	COG0298	carbon dioxide binding
FORC066_0629	COG0409	Hydrogenase expression formation protein
FORC066_0630	COG0309	Hydrogenase expression formation protein (HypE)
FORC066_0631	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FORC066_0632	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FORC066_0635	COG5001	Diguanylate cyclase
FORC066_0638	COG2197	response regulator
FORC066_0640	COG0477	Major facilitator Superfamily
FORC066_0643	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC066_0645	COG1609	Transcriptional regulator
FORC066_0646	COG0477	Major facilitator Superfamily
FORC066_0649	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC066_0650	COG0697	spore germination
FORC066_0654	COG4607	ABC-type enterochelin transport system periplasmic component
FORC066_0656	COG4605	iron ion homeostasis
FORC066_0657	COG4604	ABC transporter, ATP-binding protein
FORC066_0658	COG0024	Methionine aminopeptidase
FORC066_0663	COG1289	transmembrane transporter activity
FORC066_0665	COG1982	Orn Lys Arg decarboxylase major
FORC066_0666	COG0531	amino acid
FORC066_0670	COG2197	response regulator
FORC066_0671	COG2205	protein histidine kinase activity
FORC066_0673	COG0745	RESPONSE REGULATOR receiver
FORC066_0675	COG1982	Orn Lys Arg decarboxylase major
FORC066_0677	COG0741	lytic transglycosylase activity
FORC066_0678	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC066_0679	COG1194	a g-specific adenine glycosylase
FORC066_0680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC066_0681	COG3171	Protein conserved in bacteria
FORC066_0684	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC066_0685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC066_0686	COG1872	DUF167
FORC066_0687	COG0762	integral membrane protein
FORC066_0688	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC066_0689	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC066_0690	COG2805	Type II/IV secretion system protein
FORC066_0694	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC066_0695	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC066_0696	COG1678	Uncharacterized ACR, COG1678
FORC066_0697	COG0189	ligase activity
FORC066_0698	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC066_0699	COG2356	endonuclease I
FORC066_0700	COG3091	SprT-like family
FORC066_0704	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC066_0707	COG1166	arginine decarboxylase activity
FORC066_0710	COG0501	Belongs to the peptidase M48B family
FORC066_0711	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC066_0713	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC066_0714	COG0126	phosphoglycerate kinase activity
FORC066_0715	COG0191	fructose-bisphosphate aldolase activity
FORC066_0719	COG1279	arginine transmembrane transporter activity
FORC066_0722	COG0583	DNA-binding transcription factor activity
FORC066_0723	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC066_0724	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC066_0725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC066_0726	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC066_0727	COG3079	Belongs to the UPF0149 family
FORC066_0728	COG0006	proline dipeptidase activity
FORC066_0729	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC066_0730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC066_0732	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FORC066_0733	COG0509	glycine decarboxylation via glycine cleavage system
FORC066_0735	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC066_0735	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC066_0737	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_0739	COG1272	protein, Hemolysin III
FORC066_0740	COG0354	folic acid binding
FORC066_0743	COG0745	RESPONSE REGULATOR receiver
FORC066_0744	COG2205	protein histidine kinase activity
FORC066_0745	COG4452	Inner membrane protein CreD
FORC066_0746	COG0716	FMN binding
FORC066_0747	COG4974	Belongs to the 'phage' integrase family
FORC066_0748	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC066_0749	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC066_0750	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC066_0751	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC066_0757	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC066_0758	COG1393	Belongs to the ArsC family
FORC066_0759	COG4319	ketosteroid isomerase
FORC066_0760	COG3706	GGDEF domain
FORC066_0761	COG1522	sequence-specific DNA binding
FORC066_0764	COG2271	Major facilitator Superfamily
FORC066_0766	COG0484	heat shock protein binding
FORC066_0768	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_0769	COG1733	regulation of RNA biosynthetic process
FORC066_0770	COG0288	reversible hydration of carbon dioxide
FORC066_0775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC066_0777	COG2165	general secretion pathway protein
FORC066_0783	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FORC066_0787	COG0840	transmembrane signaling receptor activity
FORC066_0791	COG2814	Major facilitator Superfamily
FORC066_0792	COG0583	DNA-binding transcription factor activity
FORC066_0794	COG1609	Transcriptional regulator
FORC066_0798	COG0318	PFAM AMP-dependent synthetase and ligase
FORC066_0798	COG0204	Acyl-transferase
FORC066_0799	COG0477	Major facilitator Superfamily
FORC066_0800	COG0667	Aldo Keto reductase
FORC066_0801	COG0861	Integral membrane protein TerC family
FORC066_0802	COG3066	DNA modification
FORC066_0803	COG1051	belongs to the nudix hydrolase family
FORC066_0805	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FORC066_0806	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORC066_0807	COG2165	general secretion pathway protein
FORC066_0811	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC066_0812	COG1025	Belongs to the peptidase M16 family
FORC066_0813	COG1074	ATP-dependent DNA helicase activity
FORC066_0814	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC066_0815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC066_0815	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC066_0816	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC066_0817	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC066_0818	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC066_0819	COG2166	iron-sulfur cluster assembly
FORC066_0820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC066_0822	COG0583	DNA-binding transcription factor activity
FORC066_0823	COG2363	Small membrane protein
FORC066_0824	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FORC066_0825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC066_0826	COG1611	Belongs to the LOG family
FORC066_0827	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC066_0827	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC066_0830	COG3098	single-species biofilm formation
FORC066_0831	COG0564	pseudouridine synthase activity
FORC066_0834	COG2171	N-acyltransferase activity
FORC066_0835	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC066_0838	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC066_0839	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC066_0840	COG0528	UMP kinase activity
FORC066_0841	COG0233	cytoplasmic translational termination
FORC066_0842	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC066_0844	COG0575	Belongs to the CDS family
FORC066_0845	COG0750	zinc metalloprotease
FORC066_0847	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC066_0848	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC066_0849	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC066_0850	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC066_0852	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC066_0853	COG0587	DNA-directed DNA polymerase activity
FORC066_0854	COG0825	malonyl-CoA metabolic process
FORC066_0855	COG1982	Orn Lys Arg decarboxylase major
FORC066_0856	COG0346	lactoylglutathione lyase activity
FORC066_0859	COG4568	rho-dependent transcription termination
FORC066_0861	COG4681	YaeQ
FORC066_0863	COG3015	lipoprotein NlpE involved in copper resistance
FORC066_0864	COG0442	prolyl-tRNA aminoacylation
FORC066_0866	COG1720	tRNA m6t6A37 methyltransferase activity
FORC066_0868	COG1464	Belongs to the NlpA lipoprotein family
FORC066_0869	COG2011	ABC-type metal ion transport system permease component
FORC066_0871	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC066_0878	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC066_0881	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC066_0889	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_0892	COG0656	L-ascorbic acid biosynthetic process
FORC066_0893	COG0583	DNA-binding transcription factor activity
FORC066_0895	COG2814	Major facilitator Superfamily
FORC066_0896	COG3021	interspecies interaction between organisms
FORC066_0897	COG0741	lytic transglycosylase activity
FORC066_0897	COG1388	LysM domain
FORC066_0898	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC066_0899	COG2226	methyltransferase
FORC066_0900	COG0328	RNA-DNA hybrid ribonuclease activity
FORC066_0902	COG2113	Glycine betaine
FORC066_0903	COG4176	ABC-type proline glycine betaine transport system permease component
FORC066_0904	COG4175	Glycine betaine
FORC066_0906	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC066_0908	COG1780	Probably involved in ribonucleotide reductase function
FORC066_0909	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC066_0910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC066_0912	COG4575	ribosome binding
FORC066_0916	COG2207	Transcriptional regulator
FORC066_0921	COG1278	Cold shock
FORC066_0928	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC066_0929	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC066_0933	COG0831	urea catabolic process
FORC066_0935	COG0804	urea catabolic process
FORC066_0937	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FORC066_0938	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FORC066_0939	COG0829	nickel cation binding
FORC066_0940	COG4413	Urea transporter
FORC066_0941	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FORC066_0944	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC066_0947	COG2133	pyrroloquinoline quinone binding
FORC066_0949	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC066_0950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC066_0951	COG2723	6-phospho-beta-galactosidase activity
FORC066_0952	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC066_0953	COG2169	Transcriptional regulator
FORC066_0953	COG1917	Cupin 2, conserved barrel domain protein
FORC066_0954	COG3394	polysaccharide catabolic process
FORC066_0956	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC066_0958	COG1136	(ABC) transporter
FORC066_0958	COG0577	efflux transmembrane transporter activity
FORC066_0976	COG0582	viral genome integration into host DNA
FORC066_1000	COG0582	viral genome integration into host DNA
FORC066_1016	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC066_1031	COG0582	viral genome integration into host DNA
FORC066_1032	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC066_1033	COG2867	negative regulation of translational initiation
FORC066_1035	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC066_1036	COG0497	DNA recombination
FORC066_1037	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC066_1038	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC066_1039	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC066_1040	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC066_1043	COG0513	Belongs to the DEAD box helicase family
FORC066_1044	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC066_1045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC066_1048	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FORC066_1050	COG3086	response to oxidative stress
FORC066_1052	COG0481	GTPase activity
FORC066_1054	COG0571	ribonuclease III activity
FORC066_1055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC066_1056	COG1381	Involved in DNA repair and RecF pathway recombination
FORC066_1057	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC066_1058	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC066_1060	COG2610	gluconate transmembrane transporter activity
FORC066_1061	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC066_1062	COG1737	Transcriptional regulator
FORC066_1065	COG0560	Phosphoserine phosphatase
FORC066_1068	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC066_1074	COG2205	protein histidine kinase activity
FORC066_1075	COG3170	Tfp pilus assembly protein FimV
FORC066_1076	COG2204	response regulator
FORC066_1078	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC066_1078	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC066_1079	COG0347	Belongs to the P(II) protein family
FORC066_1082	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FORC066_1083	COG3457	Alanine racemase
FORC066_1085	COG2188	Transcriptional regulator
FORC066_1086	COG1017	nitric oxide dioxygenase activity
FORC066_1086	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC066_1087	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC066_1088	COG2814	Major facilitator Superfamily
FORC066_1089	COG3711	transcriptional antiterminator
FORC066_1090	COG3683	transport system, periplasmic component
FORC066_1091	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FORC066_1093	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC066_1094	COG1959	2 iron, 2 sulfur cluster binding
FORC066_1096	COG0822	iron-sulfur transferase activity
FORC066_1097	COG0316	Belongs to the HesB IscA family
FORC066_1098	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC066_1099	COG0443	Heat shock 70 kDa protein
FORC066_1100	COG0633	Ferredoxin
FORC066_1101	COG2975	iron-sulfur cluster assembly
FORC066_1104	COG3468	outer membrane autotransporter barrel domain protein
FORC066_1106	COG2373	Large extracellular alpha-helical protein
FORC066_1107	COG4953	penicillin-binding protein 1C
FORC066_1109	COG0105	UTP biosynthetic process
FORC066_1111	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORC066_1113	COG1426	Protein conserved in bacteria
FORC066_1114	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC066_1115	COG0124	histidyl-tRNA synthetase
FORC066_1116	COG2976	Protein conserved in bacteria
FORC066_1117	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC066_1119	COG1160	GTP binding
FORC066_1121	COG1645	bacterial-type flagellum-dependent swarming motility
FORC066_1122	COG1570	exodeoxyribonuclease VII activity
FORC066_1123	COG0516	GMP reductase activity
FORC066_1123	COG0517	IMP dehydrogenase activity
FORC066_1124	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC066_1124	COG0519	Catalyzes the synthesis of GMP from XMP
FORC066_1132	COG0351	phosphomethylpyrimidine kinase
FORC066_1136	COG1349	DNA-binding transcription factor activity
FORC066_1137	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_1138	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_1141	COG3730	PTS system glucitol sorbitol-specific
FORC066_1142	COG1597	lipid kinase activity
FORC066_1144	COG0826	peptidase U32
FORC066_1148	COG3422	double-strand break repair
FORC066_1149	COG0745	RESPONSE REGULATOR receiver
FORC066_1150	COG2205	protein histidine kinase activity
FORC066_1151	COG0477	Major facilitator Superfamily
FORC066_1153	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC066_1155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_1158	COG0443	Heat shock 70 kDa protein
FORC066_1159	COG3447	MASE1 domain protein
FORC066_1159	COG5001	Diguanylate cyclase
FORC066_1159	COG5002	protein histidine kinase activity
FORC066_1160	COG2239	Acts as a magnesium transporter
FORC066_1163	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC066_1164	COG0573	inorganic phosphate transmembrane transporter activity
FORC066_1165	COG0581	inorganic phosphate transmembrane transporter activity
FORC066_1169	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC066_1171	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC066_1172	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC066_1173	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC066_1174	COG2233	PERMEase
FORC066_1175	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC066_1176	COG1393	Belongs to the ArsC family
FORC066_1177	COG4783	chaperone-mediated protein folding
FORC066_1178	COG0628	permease
FORC066_1180	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC066_1181	COG2716	regulation of RNA biosynthetic process
FORC066_1182	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC066_1183	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC066_1184	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC066_1185	COG2321	neutral zinc metallopeptidase
FORC066_1186	COG2707	UPF0756 membrane protein
FORC066_1187	COG1444	tRNA N-acetyltransferase activity
FORC066_1188	COG0400	carboxylic ester hydrolase activity
FORC066_1190	COG1876	peptidase activity
FORC066_1191	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC066_1192	COG1393	Belongs to the ArsC family
FORC066_1197	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC066_1199	COG2197	response regulator
FORC066_1201	COG3062	negative regulation of establishment of protein localization
FORC066_1202	COG0243	molybdopterin cofactor binding
FORC066_1203	COG3043	anaerobic respiration
FORC066_1204	COG3005	denitrification pathway
FORC066_1205	COG0494	nUDIX hydrolase
FORC066_1208	COG2197	response regulator
FORC066_1210	COG1671	Belongs to the UPF0178 family
FORC066_1211	COG0408	coproporphyrinogen oxidase activity
FORC066_1212	COG0456	acetyltransferase
FORC066_1218	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC066_1222	COG3547	Transposase (IS116 IS110 IS902 family)
FORC066_1234	COG0456	acetyltransferase
FORC066_1236	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC066_1239	COG2837	iron assimilation
FORC066_1240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC066_1243	COG2731	YhcH YjgK YiaL family protein
FORC066_1244	COG1737	Transcriptional regulator
FORC066_1246	COG4150	thiosulfate binding
FORC066_1247	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FORC066_1248	COG4208	sulfate ABC transporter
FORC066_1252	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_1253	COG0745	RESPONSE REGULATOR receiver
FORC066_1254	COG2205	protein histidine kinase activity
FORC066_1256	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC066_1257	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_1261	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC066_1262	COG3530	Putative quorum-sensing-regulated virulence factor
FORC066_1266	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC066_1267	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC066_1268	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC066_1271	COG0667	Aldo Keto reductase
FORC066_1273	COG3961	Belongs to the TPP enzyme family
FORC066_1276	COG0837	glucose binding
FORC066_1277	COG2223	nitrite transmembrane transporter activity
FORC066_1278	COG3279	Response regulator of the LytR AlgR family
FORC066_1279	COG3275	phosphorelay sensor kinase activity
FORC066_1282	COG0436	Aminotransferase
FORC066_1283	COG3038	cytochrome b561
FORC066_1284	COG1598	PFAM Uncharacterised protein family UPF0150
FORC066_1288	COG2723	6-phospho-beta-galactosidase activity
FORC066_1290	COG1280	lysine exporter protein (LysE YggA)
FORC066_1294	COG2951	lytic endotransglycosylase activity
FORC066_1295	COG0531	amino acid
FORC066_1299	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC066_1300	COG1127	ABC transporter
FORC066_1304	COG0657	acetylesterase activity
FORC066_1304	COG2755	lipolytic protein G-D-S-L family
FORC066_1305	COG3038	cytochrome b561
FORC066_1306	COG2353	YceI-like domain
FORC066_1307	COG1609	Transcriptional regulator
FORC066_1308	COG1263	PTS System
FORC066_1308	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_1309	COG2723	6-phospho-beta-galactosidase activity
FORC066_1311	COG1695	Transcriptional regulator
FORC066_1312	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC066_1327	COG3210	domain, Protein
FORC066_1328	COG2831	hemolysin activation secretion protein
FORC066_1331	COG3121	Chaperone
FORC066_1333	COG3121	Chaperone
FORC066_1335	COG3188	usher protein
FORC066_1340	COG4977	sequence-specific DNA binding
FORC066_1347	COG2116	formate transmembrane transporter activity
FORC066_1349	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC066_1351	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC066_1352	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC066_1353	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC066_1354	COG1138	Cytochrome C-type biogenesis protein
FORC066_1355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC066_1357	COG3088	subunit of a heme lyase
FORC066_1357	COG4235	cytochrome complex assembly
FORC066_1362	COG3691	Protein conserved in bacteria
FORC066_1363	COG0183	Belongs to the thiolase family
FORC066_1364	COG1024	Enoyl-CoA hydratase
FORC066_1364	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC066_1365	COG2062	phosphohistidine phosphatase, SixA
FORC066_1366	COG2840	Smr protein MutS2
FORC066_1368	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC066_1369	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC066_1370	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FORC066_1371	COG0730	response to heat
FORC066_1372	COG3101	peptidyl-lysine hydroxylation
FORC066_1374	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC066_1374	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC066_1375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC066_1377	COG1794	racemase activity, acting on amino acids and derivatives
FORC066_1379	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC066_1380	COG2723	6-phospho-beta-galactosidase activity
FORC066_1381	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC066_1383	COG1609	Transcriptional regulator
FORC066_1385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC066_1390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC066_1391	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC066_1393	COG0697	spore germination
FORC066_1394	COG0697	spore germination
FORC066_1396	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC066_1397	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC066_1399	COG0586	Pfam SNARE associated Golgi protein
FORC066_1400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC066_1402	COG0285	dihydrofolate synthase activity
FORC066_1403	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC066_1404	COG1286	toxin biosynthetic process
FORC066_1405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC066_1407	COG0163	prenyltransferase activity
FORC066_1409	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_1410	COG4215	(ABC) transporter
FORC066_1411	COG4160	amino acid transport
FORC066_1412	COG4598	ABC transporter
FORC066_1413	COG1090	epimerase
FORC066_1415	COG0622	Phosphoesterase
FORC066_1416	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FORC066_1417	COG3037	sugar-specific permease SgaT UlaA
FORC066_1419	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_1420	COG1609	Transcriptional regulator
FORC066_1421	COG0280	phosphate acetyltransferase
FORC066_1421	COG0857	belongs to the CobB CobQ family
FORC066_1423	COG3092	negative regulation of chromosome organization
FORC066_1425	COG3013	Belongs to the UPF0304 family
FORC066_1426	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC066_1428	COG0471	metal ion transport
FORC066_1428	COG0490	domain, Protein
FORC066_1429	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC066_1431	COG0436	Aminotransferase
FORC066_1432	COG0583	DNA-binding transcription factor activity
FORC066_1433	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC066_1434	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC066_1435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC066_1435	COG0649	NAD binding
FORC066_1438	COG1034	ATP synthesis coupled electron transport
FORC066_1439	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FORC066_1440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC066_1441	COG0839	Belongs to the complex I subunit 6 family
FORC066_1442	COG0713	ATP synthesis coupled electron transport
FORC066_1443	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC066_1444	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC066_1445	COG1007	ATP synthesis coupled electron transport
FORC066_1451	COG3265	gluconokinase activity
FORC066_1452	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_1454	COG1609	Transcriptional regulator
FORC066_1455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC066_1457	COG4702	Belongs to the UPF0303 family
FORC066_1458	COG0129	dihydroxy-acid dehydratase activity
FORC066_1459	COG4575	ribosome binding
FORC066_1460	COG1169	isochorismate synthase
FORC066_1462	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORC066_1463	COG0596	Alpha beta hydrolase
FORC066_1464	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC066_1465	COG1441	menaquinone biosynthetic process
FORC066_1472	COG0814	amino acid
FORC066_1474	COG4574	serine-type endopeptidase inhibitor activity
FORC066_1476	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC066_1478	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC066_1479	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC066_1481	COG2205	protein histidine kinase activity
FORC066_1481	COG0784	Response regulator, receiver
FORC066_1483	COG0642	Histidine kinase
FORC066_1483	COG2198	Histidine kinase
FORC066_1484	COG2223	nitrite transmembrane transporter activity
FORC066_1487	COG1132	(ABC) transporter
FORC066_1491	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC066_1493	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC066_1509	COG4386	tail sheath protein
FORC066_1518	COG3299	homolog of phage Mu protein gp47
FORC066_1524	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC066_1525	COG1737	Transcriptional regulator
FORC066_1526	COG2190	(PTS) system
FORC066_1526	COG1263	PTS System
FORC066_1526	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_1527	COG2723	6-phospho-beta-galactosidase activity
FORC066_1528	COG3338	carbonate dehydratase activity
FORC066_1531	COG3082	Protein of unknown function (DUF1414)
FORC066_1532	COG3081	Nucleoid-associated protein
FORC066_1534	COG1061	Type III restriction enzyme res subunit
FORC066_1535	COG1187	pseudouridine synthase activity
FORC066_1536	COG2814	Major facilitator Superfamily
FORC066_1538	COG4172	Belongs to the ABC transporter superfamily
FORC066_1539	COG4239	(ABC) transporter, permease
FORC066_1540	COG4174	ABC transporter (Permease)
FORC066_1541	COG4166	transmembrane transport
FORC066_1542	COG2200	EAL domain
FORC066_1543	COG0791	NLP P60 protein
FORC066_1544	COG0671	phosphoesterase, PA-phosphatase related
FORC066_1545	COG0523	cobalamin synthesis protein
FORC066_1547	COG2186	Transcriptional regulator
FORC066_1548	COG0246	Mannitol dehydrogenase
FORC066_1550	COG1312	Catalyzes the dehydration of D-mannonate
FORC066_1551	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC066_1555	COG0243	molybdopterin cofactor binding
FORC066_1556	COG3005	denitrification pathway
FORC066_1561	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC066_1562	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC066_1562	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC066_1562	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC066_1563	COG3710	Transcriptional regulator
FORC066_1568	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FORC066_1569	COG2855	membrane
FORC066_1571	COG0583	DNA-binding transcription factor activity
FORC066_1572	COG0833	amino acid
FORC066_1573	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC066_1575	COG4771	TonB-dependent receptor
FORC066_1576	COG0625	glutathione transferase activity
FORC066_1582	COG2011	ABC-type metal ion transport system permease component
FORC066_1585	COG0626	cystathionine gamma-synthase activity
FORC066_1587	COG1686	Belongs to the peptidase S11 family
FORC066_1588	COG1760	l-serine dehydratase
FORC066_1589	COG0814	amino acid
FORC066_1591	COG1349	DNA-binding transcription factor activity
FORC066_1592	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC066_1593	COG0671	phosphoesterase, PA-phosphatase related
FORC066_1611	COG4695	Portal protein
FORC066_1630	COG5301	cellulose 1,4-beta-cellobiosidase activity
FORC066_1638	COG2985	domain, Protein
FORC066_1638	COG0569	domain protein
FORC066_1642	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC066_1644	COG3842	ATPase activity
FORC066_1645	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC066_1646	COG1177	transmembrane transport
FORC066_1649	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC066_1650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_1653	COG4160	amino acid transport
FORC066_1654	COG4215	(ABC) transporter
FORC066_1655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_1656	COG1126	abc transporter atp-binding protein
FORC066_1658	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC066_1659	COG0702	epimerase
FORC066_1660	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC066_1662	COG0028	Belongs to the TPP enzyme family
FORC066_1663	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC066_1664	COG1151	hydroxylamine reductase activity
FORC066_1665	COG2431	L-lysine efflux transmembrane transporter activity
FORC066_1666	COG3593	DNA synthesis involved in DNA repair
FORC066_1667	COG2990	Protein conserved in bacteria
FORC066_1668	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_1670	COG1278	Cold shock
FORC066_1671	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC066_1672	COG0542	response to heat
FORC066_1673	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC066_1674	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORC066_1676	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC066_1678	COG0492	ferredoxin-NADP+ reductase activity
FORC066_1680	COG1522	sequence-specific DNA binding
FORC066_1681	COG3107	peptidoglycan biosynthetic process
FORC066_1681	COG1674	ftsk spoiiie
FORC066_1682	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC066_1683	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC066_1684	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORC066_1685	COG2814	Major facilitator Superfamily
FORC066_1686	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC066_1687	COG1882	Formate acetyltransferase
FORC066_1688	COG2116	formate transmembrane transporter activity
FORC066_1689	COG1944	ATP diphosphatase activity
FORC066_1690	COG0252	asparaginase activity
FORC066_1691	COG2323	membrane
FORC066_1692	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORC066_1693	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC066_1694	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORC066_1695	COG0539	negative regulation of cytoplasmic translation
FORC066_1696	COG0776	regulation of translation
FORC066_1697	COG0658	competence protein
FORC066_1697	COG2333	competence protein COMEC
FORC066_1699	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC066_1700	COG5383	Protein conserved in bacteria
FORC066_1704	COG1278	Cold shock
FORC066_1705	COG2835	tetraacyldisaccharide 4'-kinase activity
FORC066_1706	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC066_1707	COG3173	Aminoglycoside phosphotransferase
FORC066_1708	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC066_1710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC066_1711	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC066_1713	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC066_1714	COG2989	Protein conserved in bacteria
FORC066_1715	COG3108	Peptidase M15
FORC066_1716	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC066_1717	COG2200	EAL domain
FORC066_1718	COG1448	Aminotransferase
FORC066_1720	COG0017	Asparaginyl-tRNA synthetase
FORC066_1721	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC066_1723	COG0308	aminopeptidase N
FORC066_1724	COG0167	dihydroorotate dehydrogenase activity
FORC066_1726	COG3217	Mosc domain protein beta barrel domain protein
FORC066_1726	COG0633	Ferredoxin
FORC066_1727	COG0116	Belongs to the methyltransferase superfamily
FORC066_1727	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC066_1728	COG0488	(ABC) transporter
FORC066_1729	COG2995	paraquat-inducible protein a
FORC066_1730	COG3008	intermembrane lipid transfer
FORC066_1730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC066_1731	COG3009	Protein conserved in bacteria
FORC066_1732	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC066_1734	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC066_1735	COG1067	ATP-dependent peptidase activity
FORC066_1736	COG3120	sequence-specific DNA binding
FORC066_1738	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FORC066_1739	COG3070	regulator of competence-specific genes
FORC066_1740	COG1289	transmembrane transporter activity
FORC066_1741	COG3304	Inner membrane component domain
FORC066_1742	COG0210	DNA helicase
FORC066_1743	COG1803	Methylglyoxal synthase
FORC066_1745	COG1832	CoA-binding protein
FORC066_1746	COG3785	DNA binding
FORC066_1747	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC066_1750	COG1254	Belongs to the acylphosphatase family
FORC066_1751	COG2920	part of a sulfur-relay system
FORC066_1755	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC066_1756	COG0437	4 iron, 4 sulfur cluster binding
FORC066_1757	COG3301	Polysulphide reductase, NrfD
FORC066_1758	COG1138	Cytochrome C-type biogenesis protein
FORC066_1759	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC066_1760	COG3088	subunit of a heme lyase
FORC066_1761	COG4235	cytochrome complex assembly
FORC066_1762	COG2771	luxR family
FORC066_1763	COG3916	Acyl-homoserine-lactone synthase
FORC066_1765	COG3263	regulation of cellular component size
FORC066_1768	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FORC066_1769	COG2943	transferase activity, transferring hexosyl groups
FORC066_1770	COG5645	(Lipo)protein
FORC066_1774	COG2814	Major facilitator Superfamily
FORC066_1776	COG2259	Doxx family
FORC066_1777	COG1560	Kdo2-lipid A biosynthetic process
FORC066_1784	COG1054	Belongs to the UPF0176 family
FORC066_1785	COG0628	permease
FORC066_1791	COG0418	dihydroorotase activity
FORC066_1792	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC066_1793	COG1530	ribonuclease E activity
FORC066_1793	COG1530	ribonuclease E activity
FORC066_1794	COG0564	pseudouridine synthase activity
FORC066_1795	COG0424	maF-like protein
FORC066_1796	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC066_1797	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC066_1798	COG0416	fatty acid biosynthetic process
FORC066_1799	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC066_1801	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_1803	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC066_1804	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC066_1805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC066_1806	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC066_1807	COG0470	DNA polymerase III
FORC066_1808	COG0084	hydrolase, TatD family'
FORC066_1809	COG1263	PTS System
FORC066_1809	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_1811	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC066_1812	COG0537	adenosine 5'-monophosphoramidase activity
FORC066_1813	COG5633	Lipoprotein
FORC066_1814	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FORC066_1816	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC066_1817	COG3150	esterase
FORC066_1818	COG1252	NADH dehydrogenase
FORC066_1820	COG3134	Outer membrane lipoprotein
FORC066_1821	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC066_1822	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC066_1824	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC066_1825	COG1940	carbohydrate kinase activity
FORC066_1828	COG2850	peptidyl-arginine hydroxylation
FORC066_1830	COG0745	RESPONSE REGULATOR receiver
FORC066_1832	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC066_1833	COG2915	High frequency lysogenization protein hflD homolog
FORC066_1834	COG0482	sulfurtransferase activity
FORC066_1836	COG1187	pseudouridine synthase activity
FORC066_1837	COG0538	isocitrate dehydrogenase activity
FORC066_1839	COG3157	Type VI secretion system effector, Hcp
FORC066_1849	COG0840	transmembrane signaling receptor activity
FORC066_1856	COG3772	lysozyme
FORC066_1860	COG2873	o-acetylhomoserine
FORC066_1861	COG0702	epimerase
FORC066_1862	COG1733	regulation of RNA biosynthetic process
FORC066_1867	COG0765	amino acid transport
FORC066_1868	COG0765	amino acid transport
FORC066_1869	COG1126	abc transporter atp-binding protein
FORC066_1870	COG2721	sulfolactate sulfo-lyase activity
FORC066_1871	COG0246	Mannitol dehydrogenase
FORC066_1872	COG1063	alcohol dehydrogenase
FORC066_1873	COG1802	Transcriptional regulator
FORC066_1874	COG4948	Mandelate Racemase Muconate Lactonizing
FORC066_1876	COG2271	Major facilitator Superfamily
FORC066_1880	COG3755	Protein conserved in bacteria
FORC066_1883	COG2203	Gaf domain
FORC066_1883	COG4251	negative regulation of phosphorylation
FORC066_1883	COG5001	Diguanylate cyclase
FORC066_1883	COG3706	GGDEF domain
FORC066_1887	COG1132	(ABC) transporter
FORC066_1892	COG2207	Transcriptional regulator
FORC066_1900	COG1113	amino acid transport
FORC066_1904	COG1496	oxidoreductase activity
FORC066_1905	COG0768	penicillin binding
FORC066_1906	COG2226	methyltransferase
FORC066_1908	COG5002	protein histidine kinase activity
FORC066_1908	COG3447	MASE1 domain protein
FORC066_1908	COG5001	Diguanylate cyclase
FORC066_1911	COG1971	Probably functions as a manganese efflux pump
FORC066_1912	COG4811	Protein of unknown function (DUF986)
FORC066_1913	COG3716	PTS system mannose fructose sorbose family IID component
FORC066_1914	COG3715	PTS system
FORC066_1915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_1915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_1916	COG1253	flavin adenine dinucleotide binding
FORC066_1920	COG1760	l-serine dehydratase
FORC066_1923	COG0494	nUDIX hydrolase
FORC066_1925	COG3140	Belongs to the UPF0181 family
FORC066_1926	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC066_1928	COG0513	Belongs to the DEAD box helicase family
FORC066_1929	COG3141	response to X-ray
FORC066_1930	COG3097	Belongs to the UPF0267 family
FORC066_1932	COG1770	oligopeptidase
FORC066_1933	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC066_1937	COG1528	Iron-storage protein
FORC066_1939	COG2372	response to copper ion
FORC066_1940	COG1276	copper resistance
FORC066_1942	COG0582	viral genome integration into host DNA
FORC066_1950	COG1396	sequence-specific DNA binding
FORC066_1967	COG3772	lysozyme
FORC066_1977	COG1475	DNA binding
FORC066_1982	COG2026	Addiction module toxin, RelE StbE family
FORC066_1983	COG3077	Addiction module antitoxin, RelB DinJ family
FORC066_1985	COG3567	Phage-associated protein, HI1409 family
FORC066_1987	COG3566	protein conserved in bacteria
FORC066_2022	COG3157	Type VI secretion system effector, Hcp
FORC066_2023	COG0488	(ABC) transporter
FORC066_2032	COG3772	lysozyme
FORC066_2033	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC066_2035	COG2979	Protein of unknown function (DUF533)
FORC066_2038	COG2186	Transcriptional regulator
FORC066_2039	COG3734	2-keto-3-deoxy-galactonokinase
FORC066_2040	COG0800	Aldolase
FORC066_2041	COG4948	Mandelate Racemase Muconate Lactonizing
FORC066_2043	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC066_2044	COG0012	GTP binding
FORC066_2046	COG0193	aminoacyl-tRNA hydrolase activity
FORC066_2051	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC066_2053	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FORC066_2054	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC066_2055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC066_2056	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC066_2059	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC066_2060	COG0659	secondary active sulfate transmembrane transporter activity
FORC066_2061	COG3706	GGDEF domain
FORC066_2066	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC066_2067	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC066_2068	COG3381	protein complex oligomerization
FORC066_2071	COG0477	Major facilitator Superfamily
FORC066_2076	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC066_2078	COG0673	inositol 2-dehydrogenase activity
FORC066_2079	COG0728	peptidoglycan biosynthetic process
FORC066_2080	COG0018	arginyl-trna synthetase
FORC066_2081	COG3102	Protein conserved in bacteria
FORC066_2082	COG3142	Participates in the control of copper homeostasis
FORC066_2083	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC066_2084	COG2226	methyltransferase
FORC066_2085	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FORC066_2086	COG1801	Protein of unknown function DUF72
FORC066_2087	COG1335	isochorismatase
FORC066_2089	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC066_2090	COG0494	nUDIX hydrolase
FORC066_2091	COG0217	transcriptional regulatory protein
FORC066_2092	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORC066_2093	COG0632	four-way junction helicase activity
FORC066_2094	COG2255	four-way junction helicase activity
FORC066_2095	COG3104	oligopeptide transport
FORC066_2096	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC066_2097	COG1121	(ABC) transporter
FORC066_2098	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC066_2099	COG0739	heme binding
FORC066_2100	COG1560	Kdo2-lipid A biosynthetic process
FORC066_2101	COG0469	pyruvate kinase activity
FORC066_2102	COG1737	Transcriptional regulator
FORC066_2103	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC066_2104	COG0800	Aldolase
FORC066_2106	COG2076	Multidrug Resistance protein
FORC066_2107	COG2076	Multidrug Resistance protein
FORC066_2108	COG0251	oxidation-reduction process
FORC066_2109	COG1199	ATP-dependent helicase activity
FORC066_2111	COG3065	identical protein binding
FORC066_2112	COG0318	PFAM AMP-dependent synthetase and ligase
FORC066_2113	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC066_2114	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC066_2115	COG2894	cell division
FORC066_2116	COG0850	regulation of cytokinetic process
FORC066_2118	COG3100	YcgL domain-containing protein
FORC066_2119	COG2951	lytic endotransglycosylase activity
FORC066_2120	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC066_2121	COG2983	Belongs to the UPF0260 family
FORC066_2124	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FORC066_2125	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC066_2126	COG2186	Transcriptional regulator
FORC066_2127	COG2719	SpoVR family
FORC066_2129	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC066_2130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC066_2131	COG2814	Major facilitator Superfamily
FORC066_2132	COG2199	diguanylate cyclase activity
FORC066_2132	COG2200	EAL domain
FORC066_2132	COG2202	Pas domain
FORC066_2134	COG0583	DNA-binding transcription factor activity
FORC066_2137	COG2718	Belongs to the UPF0229 family
FORC066_2138	COG2766	serine protein kinase
FORC066_2139	COG3713	MltA-interacting MipA family protein
FORC066_2143	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC066_2144	COG3139	Protein of unknown function (DUF1315)
FORC066_2145	COG1335	isochorismatase
FORC066_2146	COG0252	asparaginase activity
FORC066_2147	COG0616	signal peptide processing
FORC066_2148	COG0778	Nitroreductase
FORC066_2150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC066_2152	COG0494	nUDIX hydrolase
FORC066_2153	COG0708	Exodeoxyribonuclease III
FORC066_2155	COG0583	DNA-binding transcription factor activity
FORC066_2156	COG0788	formyltetrahydrofolate deformylase activity
FORC066_2157	COG3012	SEC-C Motif Domain Protein
FORC066_2159	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC066_2160	COG0745	RESPONSE REGULATOR receiver
FORC066_2162	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC066_2165	COG1012	belongs to the aldehyde dehydrogenase family
FORC066_2165	COG1454	alcohol dehydrogenase
FORC066_2166	COG2095	MarC family integral membrane protein
FORC066_2172	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC066_2173	COG0444	Belongs to the ABC transporter superfamily
FORC066_2176	COG3099	Belongs to the UPF0263 family
FORC066_2177	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC066_2181	COG2350	Protein conserved in bacteria
FORC066_2182	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC066_2184	COG2917	probably involved in intracellular septation
FORC066_2187	COG0727	PFAM Uncharacterised protein family (UPF0153)
FORC066_2188	COG3047	cAMP biosynthetic process
FORC066_2190	COG0159	tryptophan synthase activity
FORC066_2197	COG0159	tryptophan synthase activity
FORC066_2198	COG0133	tryptophan synthase activity
FORC066_2200	COG0135	phosphoribosylanthranilate isomerase activity
FORC066_2200	COG0134	indole-3-glycerol-phosphate synthase activity
FORC066_2202	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC066_2205	COG0613	PHP domain protein
FORC066_2206	COG0009	L-threonylcarbamoyladenylate synthase
FORC066_2207	COG1187	pseudouridine synthase activity
FORC066_2208	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC066_2209	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_2210	COG0616	signal peptide processing
FORC066_2213	COG0583	DNA-binding transcription factor activity
FORC066_2216	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC066_2218	COG0671	phosphoesterase, PA-phosphatase related
FORC066_2219	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC066_2220	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC066_2222	COG1396	sequence-specific DNA binding
FORC066_2223	COG3135	benzoate transporter
FORC066_2226	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC066_2227	COG0023	Translation Initiation Factor
FORC066_2230	COG0235	Class ii aldolase
FORC066_2232	COG1349	DNA-binding transcription factor activity
FORC066_2233	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC066_2234	COG2879	small protein
FORC066_2235	COG1966	Carbon starvation protein
FORC066_2236	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC066_2237	COG0243	molybdopterin cofactor binding
FORC066_2240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC066_2242	COG4659	FMN binding
FORC066_2243	COG4658	electron transport chain
FORC066_2244	COG3708	Transcriptional regulator
FORC066_2244	COG2207	Transcriptional regulator
FORC066_2245	COG4656	Part of a membrane complex involved in electron transport
FORC066_2247	COG4657	Part of a membrane complex involved in electron transport
FORC066_2250	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC066_2255	COG2160	L-arabinose isomerase activity
FORC066_2257	COG1879	ABC-type sugar transport system periplasmic component
FORC066_2258	COG1129	ABC transporter
FORC066_2259	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_2261	COG0673	inositol 2-dehydrogenase activity
FORC066_2263	COG0385	Bile acid
FORC066_2264	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC066_2266	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC066_2267	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_2267	COG1263	PTS System
FORC066_2268	COG1609	Transcriptional regulator
FORC066_2270	COG5339	Protein conserved in bacteria
FORC066_2272	COG0114	fumarate hydratase activity
FORC066_2278	COG2814	Major facilitator Superfamily
FORC066_2279	COG0583	DNA-binding transcription factor activity
FORC066_2280	COG1940	carbohydrate kinase activity
FORC066_2281	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC066_2287	COG1742	UPF0060 membrane protein
FORC066_2288	COG4221	oxidoreductase activity
FORC066_2289	COG0477	Major facilitator Superfamily
FORC066_2294	COG0625	glutathione transferase activity
FORC066_2298	COG3604	Transcriptional regulator
FORC066_2299	COG1773	rubredoxin
FORC066_2299	COG0426	domain, Protein
FORC066_2300	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC066_2302	COG1522	sequence-specific DNA binding
FORC066_2308	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC066_2310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC066_2312	COG0483	inositol monophosphate 1-phosphatase activity
FORC066_2313	COG2271	Major facilitator Superfamily
FORC066_2317	COG0028	Belongs to the TPP enzyme family
FORC066_2318	COG0440	acetolactate synthase activity
FORC066_2319	COG1011	Hydrolase
FORC066_2323	COG0738	Major facilitator superfamily
FORC066_2324	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC066_2326	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_2328	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FORC066_2331	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC066_2332	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC066_2333	COG0589	response to stress
FORC066_2334	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC066_2335	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC066_2338	COG0531	amino acid
FORC066_2340	COG0745	RESPONSE REGULATOR receiver
FORC066_2341	COG2205	protein histidine kinase activity
FORC066_2342	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC066_2345	COG3591	Belongs to the peptidase S1B family
FORC066_2348	COG1643	Atp-dependent helicase
FORC066_2349	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC066_2351	COG0246	Mannitol dehydrogenase
FORC066_2352	COG1070	Carbohydrate kinase
FORC066_2354	COG3784	Protein of unknown function (DUF1318)
FORC066_2356	COG2911	Protein conserved in bacteria
FORC066_2357	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC066_2358	COG3042	response to heat
FORC066_2359	COG1285	pathogenesis
FORC066_2362	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FORC066_2362	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC066_2362	COG1013	pyruvate-flavodoxin oxidoreductase activity
FORC066_2362	COG0674	pyruvate-flavodoxin oxidoreductase activity
FORC066_2363	COG2723	6-phospho-beta-galactosidase activity
FORC066_2364	COG2190	(PTS) system
FORC066_2364	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_2364	COG1263	PTS System
FORC066_2365	COG3711	transcriptional antiterminator
FORC066_2366	COG0037	tRNA processing
FORC066_2367	COG0598	Magnesium transport protein CorA
FORC066_2371	COG4166	transmembrane transport
FORC066_2372	COG2866	Carboxypeptidase
FORC066_2373	COG4948	Mandelate Racemase Muconate Lactonizing
FORC066_2374	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FORC066_2376	COG5642	Protein of unknown function (DUF2384)
FORC066_2377	COG5654	RES domain protein
FORC066_2379	COG3106	COG3106 Predicted ATPase
FORC066_2381	COG1983	PspC domain protein
FORC066_2383	COG1842	Phage shock protein A
FORC066_2384	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC066_2387	COG4166	transmembrane transport
FORC066_2389	COG4171	peptide transport system, permease
FORC066_2391	COG4172	Belongs to the ABC transporter superfamily
FORC066_2394	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC066_2394	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC066_2396	COG3104	oligopeptide transport
FORC066_2401	COG0625	glutathione transferase activity
FORC066_2403	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC066_2404	COG0259	pyridoxamine-phosphate oxidase activity
FORC066_2405	COG3895	Periplasmic Protein
FORC066_2406	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC066_2407	COG3133	Outer membrane lipoprotein
FORC066_2408	COG1846	Transcriptional regulator
FORC066_2410	COG1566	PFAM secretion protein HlyD family protein
FORC066_2411	COG1289	transmembrane transporter activity
FORC066_2412	COG4989	oxidoreductase activity
FORC066_2413	COG3313	Fe-S protein
FORC066_2414	COG2194	sulfuric ester hydrolase activity
FORC066_2415	COG1309	transcriptional regulator
FORC066_2416	COG1902	pentaerythritol trinitrate reductase activity
FORC066_2417	COG0346	lactoylglutathione lyase activity
FORC066_2418	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC066_2419	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC066_2420	COG0791	NLP P60 protein
FORC066_2423	COG1609	Transcriptional regulator
FORC066_2424	COG0583	DNA-binding transcription factor activity
FORC066_2425	COG2814	Major facilitator Superfamily
FORC066_2426	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC066_2427	COG0307	riboflavin synthase, alpha
FORC066_2428	COG0534	Mate efflux family protein
FORC066_2431	COG1388	LysM domain
FORC066_2431	COG1376	ErfK ybiS ycfS ynhG family protein
FORC066_2432	COG2166	iron-sulfur cluster assembly
FORC066_2434	COG0719	Fe-S assembly protein
FORC066_2435	COG0396	ATPase activity
FORC066_2436	COG0719	Fe-S assembly protein
FORC066_2437	COG0316	Belongs to the HesB IscA family
FORC066_2438	COG2050	protein possibly involved in aromatic compounds catabolism
FORC066_2439	COG0247	lactate metabolic process
FORC066_2439	COG0277	FAD linked oxidase domain protein
FORC066_2440	COG0628	permease
FORC066_2441	COG0574	Belongs to the PEP-utilizing enzyme family
FORC066_2441	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC066_2442	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC066_2445	COG4771	TonB-dependent receptor
FORC066_2446	COG3720	iron ion transport
FORC066_2447	COG4558	Periplasmic binding protein
FORC066_2449	COG0095	Lipoate-protein ligase
FORC066_2450	COG0791	NLP P60 protein
FORC066_2451	COG2076	Multidrug Resistance protein
FORC066_2452	COG2076	Multidrug Resistance protein
FORC066_2453	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FORC066_2454	COG0726	polysaccharide deacetylase
FORC066_2455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC066_2455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC066_2456	COG0463	Glycosyl transferase, family 2
FORC066_2457	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC066_2458	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC066_2459	COG0386	Belongs to the glutathione peroxidase family
FORC066_2460	COG4139	cobalamin transport
FORC066_2463	COG0776	regulation of translation
FORC066_2465	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC066_2466	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FORC066_2467	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC066_2468	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FORC066_2469	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC066_2472	COG1811	Na channel or pump
FORC066_2480	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC066_2481	COG1121	(ABC) transporter
FORC066_2482	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC066_2483	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC066_2484	COG3001	Fructosamine kinase
FORC066_2485	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC066_2485	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC066_2486	COG1703	isobutyryl-CoA mutase activity
FORC066_2487	COG1024	Enoyl-CoA hydratase
FORC066_2488	COG0427	acetyl-CoA hydrolase
FORC066_2489	COG0583	DNA-binding transcription factor activity
FORC066_2491	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC066_2492	COG1917	Cupin 2, conserved barrel domain protein
FORC066_2493	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FORC066_2494	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_2497	COG1175	transmembrane transport
FORC066_2498	COG0395	ABC-type sugar transport system, permease component
FORC066_2499	COG3842	ATPase activity
FORC066_2500	COG1653	transport
FORC066_2501	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC066_2503	COG1988	membrane-bound metal-dependent
FORC066_2504	COG1823	symporter activity
FORC066_2505	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC066_2507	COG0823	Involved in the tonB-independent uptake of proteins
FORC066_2508	COG2814	Major facilitator Superfamily
FORC066_2514	COG0501	Belongs to the peptidase M48B family
FORC066_2515	COG0793	Belongs to the peptidase S41A family
FORC066_2517	COG1956	GAF domain-containing protein
FORC066_2518	COG2995	paraquat-inducible protein a
FORC066_2519	COG3008	intermembrane lipid transfer
FORC066_2521	COG2814	Major facilitator Superfamily
FORC066_2529	COG5001	Diguanylate cyclase
FORC066_2529	COG3706	GGDEF domain
FORC066_2529	COG4251	negative regulation of phosphorylation
FORC066_2529	COG2203	Gaf domain
FORC066_2538	COG0625	glutathione transferase activity
FORC066_2539	COG0668	transmembrane transport
FORC066_2543	COG0786	glutamate:sodium symporter activity
FORC066_2544	COG1187	pseudouridine synthase activity
FORC066_2547	COG1349	DNA-binding transcription factor activity
FORC066_2549	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_2552	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_2553	COG2222	sugar isomerase
FORC066_2555	COG4942	peptidase
FORC066_2558	COG3443	Belongs to the bacterial solute-binding protein 9 family
FORC066_2561	COG0402	S-adenosylhomocysteine deaminase activity
FORC066_2563	COG1228	amidohydrolase
FORC066_2566	COG2988	succinylglutamate desuccinylase activity
FORC066_2567	COG3724	N-succinylarginine dihydrolase activity
FORC066_2569	COG3138	arginine N-succinyltransferase
FORC066_2570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC066_2571	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC066_2572	COG1271	oxidase subunit
FORC066_2573	COG1294	oxidase, subunit
FORC066_2575	COG3850	Histidine kinase
FORC066_2576	COG0583	DNA-binding transcription factor activity
FORC066_2577	COG2814	Major facilitator Superfamily
FORC066_2579	COG0387	Pfam Sodium calcium exchanger
FORC066_2580	COG1702	phosphate starvation-inducible protein PhoH
FORC066_2584	COG3658	cytochrome
FORC066_2585	COG1215	transferase activity, transferring glycosyl groups
FORC066_2586	COG0726	polysaccharide deacetylase
FORC066_2586	COG1649	PFAM Uncharacterised BCR, COG1649
FORC066_2587	COG0457	Tetratricopeptide repeat
FORC066_2589	COG4114	ferric iron reductase
FORC066_2590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC066_2595	COG0577	efflux transmembrane transporter activity
FORC066_2595	COG1136	(ABC) transporter
FORC066_2597	COG1136	(ABC) transporter
FORC066_2597	COG0577	efflux transmembrane transporter activity
FORC066_2600	COG0672	)-iron permease
FORC066_2603	COG2066	Belongs to the glutaminase family
FORC066_2604	COG3622	Belongs to the hyi family
FORC066_2605	COG0235	Class ii aldolase
FORC066_2606	COG3395	kinase activity
FORC066_2607	COG1349	DNA-binding transcription factor activity
FORC066_2608	COG3290	protein histidine kinase activity
FORC066_2609	COG4565	transcriptional regulatory protein
FORC066_2610	COG3493	citrate carrier protein
FORC066_2615	COG0346	lactoylglutathione lyase activity
FORC066_2617	COG2223	nitrite transmembrane transporter activity
FORC066_2618	COG0561	phosphatase activity
FORC066_2623	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC066_2642	COG4974	Belongs to the 'phage' integrase family
FORC066_2660	COG4695	Portal protein
FORC066_2694	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC066_2695	COG0322	excinuclease ABC activity
FORC066_2696	COG2197	response regulator
FORC066_2698	COG3136	membrane protein required for alginate biosynthesis
FORC066_2700	COG0366	Alpha amylase catalytic
FORC066_2703	COG2226	methyltransferase
FORC066_2706	COG1113	amino acid transport
FORC066_2707	COG1309	transcriptional regulator
FORC066_2709	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC066_2710	COG1335	isochorismatase
FORC066_2711	COG0251	oxidation-reduction process
FORC066_2712	COG2267	carboxylic ester hydrolase activity
FORC066_2713	COG0778	Nitroreductase
FORC066_2714	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC066_2715	COG2233	PERMEase
FORC066_2716	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC066_2718	COG0655	NAD(P)H dehydrogenase (quinone) activity
FORC066_2720	COG2822	iron ion transport
FORC066_2721	COG0672	)-iron permease
FORC066_2723	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FORC066_2723	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FORC066_2723	COG0506	proline dehydrogenase activity
FORC066_2726	COG1126	abc transporter atp-binding protein
FORC066_2728	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_2729	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORC066_2731	COG1191	sigma factor activity
FORC066_2742	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC066_2743	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC066_2744	COG1677	Flagellar hook-basal body complex protein FliE
FORC066_2748	COG1317	bacterial-type flagellum organization
FORC066_2753	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC066_2757	COG1338	Plays a role in the flagellum-specific transport system
FORC066_2762	COG1256	bacterial-type flagellum assembly
FORC066_2768	COG1749	Flagellar hook protein flgE
FORC066_2769	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC066_2770	COG1558	bacterial-type flagellum-dependent cell motility
FORC066_2771	COG1815	bacterial-type flagellum-dependent cell motility
FORC066_2773	COG2747	anti-sigma28 factor FlgM
FORC066_2774	COG3418	PFAM FlgN family protein
FORC066_2777	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC066_2778	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC066_2779	COG1404	Belongs to the peptidase S8 family
FORC066_2779	COG4935	Belongs to the peptidase S8 family
FORC066_2780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC066_2781	COG0745	RESPONSE REGULATOR receiver
FORC066_2783	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC066_2784	COG0840	transmembrane signaling receptor activity
FORC066_2785	COG0840	transmembrane signaling receptor activity
FORC066_2786	COG0835	chemotaxis
FORC066_2787	COG0643	Histidine kinase
FORC066_2787	COG2198	Histidine kinase
FORC066_2788	COG1360	Flagellar Motor Protein
FORC066_2793	COG0589	response to stress
FORC066_2794	COG2130	NADP-dependent
FORC066_2796	COG1285	pathogenesis
FORC066_2797	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FORC066_2798	COG0840	transmembrane signaling receptor activity
FORC066_2802	COG1609	Transcriptional regulator
FORC066_2803	COG3250	beta-galactosidase activity
FORC066_2804	COG0604	alcohol dehydrogenase
FORC066_2804	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_2804	COG3321	synthase
FORC066_2810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC066_2812	COG3121	Chaperone
FORC066_2817	COG1070	Carbohydrate kinase
FORC066_2818	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC066_2820	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_2821	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_2822	COG1129	ABC transporter
FORC066_2824	COG3228	Belongs to the MtfA family
FORC066_2826	COG3122	Protein conserved in bacteria
FORC066_2827	COG1136	(ABC) transporter
FORC066_2828	COG0577	efflux transmembrane transporter activity
FORC066_2828	COG1136	(ABC) transporter
FORC066_2834	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_2834	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_2835	COG2814	Major facilitator Superfamily
FORC066_2838	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC066_2841	COG0471	metal ion transport
FORC066_2844	COG3051	citrate lyase alpha subunit
FORC066_2845	COG2301	Belongs to the HpcH HpaI aldolase family
FORC066_2846	COG3052	prosthetic group binding
FORC066_2847	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FORC066_2848	COG3290	protein histidine kinase activity
FORC066_2849	COG4565	transcriptional regulatory protein
FORC066_2853	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC066_2855	COG3842	ATPase activity
FORC066_2857	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_2857	COG2205	protein histidine kinase activity
FORC066_2862	COG3121	Chaperone
FORC066_2867	COG1063	alcohol dehydrogenase
FORC066_2869	COG4221	oxidoreductase activity
FORC066_2871	COG0784	Response regulator, receiver
FORC066_2871	COG0835	chemotaxis
FORC066_2873	COG1349	DNA-binding transcription factor activity
FORC066_2874	COG0561	phosphatase activity
FORC066_2876	COG0352	thiamine-phosphate diphosphorylase activity
FORC066_2880	COG0534	Mate efflux family protein
FORC066_2881	COG0137	argininosuccinate synthase activity
FORC066_2896	COG3188	usher protein
FORC066_2897	COG3121	Chaperone
FORC066_2912	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC066_2914	COG0583	DNA-binding transcription factor activity
FORC066_2915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FORC066_2917	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC066_2919	COG1492	cobalamin metabolic process
FORC066_2932	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FORC066_2934	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FORC066_2951	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FORC066_2952	COG2096	Adenosyltransferase
FORC066_2955	COG4656	Part of a membrane complex involved in electron transport
FORC066_2959	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC066_2960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC066_2960	COG1648	precorrin-2 dehydrogenase activity
FORC066_2961	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC066_2963	COG2197	response regulator
FORC066_2966	COG1129	ABC transporter
FORC066_2967	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_2969	COG2926	Belongs to the UPF0265 family
FORC066_2970	COG1289	transmembrane transporter activity
FORC066_2971	COG1022	Amp-dependent synthetase and ligase
FORC066_2971	COG3320	Male sterility
FORC066_2972	COG2925	Exonuclease
FORC066_2973	COG0531	amino acid
FORC066_2974	COG0371	Dehydrogenase
FORC066_2975	COG1129	ABC transporter
FORC066_2976	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_2977	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC066_2979	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC066_2981	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC066_2982	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC066_2982	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC066_2984	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC066_2985	COG0107	imidazoleglycerol-phosphate synthase activity
FORC066_2986	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC066_2986	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC066_2987	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC066_2988	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC066_2989	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC066_2990	COG1253	flavin adenine dinucleotide binding
FORC066_2991	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC066_2992	COG2982	Protein involved in outer membrane biogenesis
FORC066_2994	COG0572	uridine kinase
FORC066_2995	COG0489	protein tyrosine kinase activity
FORC066_2997	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC066_2997	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC066_3001	COG2814	Major facilitator Superfamily
FORC066_3002	COG1380	Effector of murein hydrolase LrgA
FORC066_3003	COG1346	cytolysis
FORC066_3006	COG0281	malic enzyme
FORC066_3007	COG2949	membrane
FORC066_3008	COG0298	carbon dioxide binding
FORC066_3009	COG0375	protein maturation
FORC066_3010	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC066_3011	COG0651	ATP synthesis coupled electron transport
FORC066_3012	COG0650	Formate hydrogenlyase subunit 4
FORC066_3013	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC066_3014	COG4237	Hydrogenase 4 membrane
FORC066_3015	COG0651	ATP synthesis coupled electron transport
FORC066_3016	COG3261	NADH dehydrogenase
FORC066_3016	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FORC066_3017	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC066_3018	COG3260	NADH ubiquinone oxidoreductase 20
FORC066_3020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FORC066_3022	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC066_3023	COG3383	formate dehydrogenase (NAD+) activity
FORC066_3024	COG3604	Transcriptional regulator
FORC066_3025	COG2116	formate transmembrane transporter activity
FORC066_3030	COG2311	Membrane
FORC066_3031	COG0302	gtp cyclohydrolase
FORC066_3032	COG0477	Major facilitator Superfamily
FORC066_3033	COG0583	DNA-binding transcription factor activity
FORC066_3039	COG1136	(ABC) transporter
FORC066_3039	COG0577	efflux transmembrane transporter activity
FORC066_3042	COG0303	'Molybdopterin
FORC066_3043	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC066_3044	COG0488	(ABC) transporter
FORC066_3049	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FORC066_3053	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FORC066_3056	COG4106	trans-aconitate 2-methyltransferase activity
FORC066_3057	COG0783	Belongs to the Dps family
FORC066_3058	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC066_3060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_3061	COG0765	amino acid transport
FORC066_3062	COG1126	abc transporter atp-binding protein
FORC066_3064	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FORC066_3068	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC066_3070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC066_3075	COG0697	spore germination
FORC066_3077	COG0583	DNA-binding transcription factor activity
FORC066_3080	COG1174	glycine betaine transport
FORC066_3081	COG1125	glycine betaine transport
FORC066_3082	COG1174	glycine betaine transport
FORC066_3084	COG1732	Glycine betaine
FORC066_3088	COG2897	thiosulfate sulfurtransferase activity
FORC066_3094	COG4807	Protein conserved in bacteria
FORC066_3097	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FORC066_3099	COG2261	transglycosylase associated protein
FORC066_3103	COG0277	FAD linked oxidase domain protein
FORC066_3106	COG1686	Belongs to the peptidase S11 family
FORC066_3109	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC066_3110	COG0513	Belongs to the DEAD box helicase family
FORC066_3111	COG1309	transcriptional regulator
FORC066_3112	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_3113	COG1131	(ABC) transporter
FORC066_3114	COG0842	Transport permease protein
FORC066_3115	COG0842	Transport permease protein
FORC066_3116	COG0670	Belongs to the BI1 family
FORC066_3117	COG0314	molybdopterin synthase activity
FORC066_3118	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC066_3119	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC066_3120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC066_3121	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC066_3122	COG4628	conserved protein (DUF2132)
FORC066_3123	COG0556	nucleotide-excision repair
FORC066_3127	COG2226	methyltransferase
FORC066_3128	COG0156	8-amino-7-oxononanoate synthase activity
FORC066_3129	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC066_3131	COG2706	6-phosphogluconolactonase activity
FORC066_3132	COG0561	phosphatase activity
FORC066_3134	COG4149	molybdate abc transporter
FORC066_3135	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC066_3138	COG3585	molybdate ion transport
FORC066_3138	COG2005	Transcriptional regulator
FORC066_3140	COG1119	ATPase activity
FORC066_3142	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC066_3143	COG1085	galactose-1-phosphate uridylyltransferase
FORC066_3144	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC066_3145	COG2017	converts alpha-aldose to the beta-anomer
FORC066_3149	COG0588	phosphoglycerate mutase activity
FORC066_3150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC066_3151	COG1230	cation diffusion facilitator family transporter
FORC066_3153	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC066_3155	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC066_3156	COG2885	chlorophyll binding
FORC066_3157	COG0823	Involved in the tonB-independent uptake of proteins
FORC066_3158	COG3064	Membrane
FORC066_3158	COG3064	Membrane
FORC066_3159	COG0848	biopolymer transport protein
FORC066_3160	COG0811	peptide transport
FORC066_3161	COG0824	Thioesterase
FORC066_3162	COG3790	cyd operon protein YbgE
FORC066_3163	COG4890	Cyd operon protein YbgT
FORC066_3164	COG1294	oxidase, subunit
FORC066_3165	COG1271	oxidase subunit
FORC066_3166	COG0737	Belongs to the 5'-nucleotidase family
FORC066_3167	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FORC066_3168	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC066_3169	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC066_3170	COG0567	Dehydrogenase, E1 component
FORC066_3172	COG1053	succinate dehydrogenase
FORC066_3173	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC066_3174	COG2009	succinate dehydrogenase
FORC066_3176	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FORC066_3179	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC066_3180	COG1984	allophanate hydrolase subunit 2
FORC066_3181	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC066_3183	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC066_3184	COG5212	phosphodiesterase
FORC066_3186	COG3272	Protein of unknown function (DUF1722)
FORC066_3187	COG1073	alpha beta
FORC066_3187	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC066_3187	COG3064	Membrane
FORC066_3187	COG1073	alpha beta
FORC066_3187	COG3064	Membrane
FORC066_3187	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC066_3188	COG2994	toxin metabolic process
FORC066_3193	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FORC066_3194	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FORC066_3195	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FORC066_3196	COG2205	protein histidine kinase activity
FORC066_3197	COG0745	RESPONSE REGULATOR receiver
FORC066_3200	COG0033	Phosphoglucomutase
FORC066_3201	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC066_3203	COG2966	Psort location CytoplasmicMembrane, score
FORC066_3205	COG0427	acetyl-CoA hydrolase
FORC066_3206	COG1024	Enoyl-CoA hydratase
FORC066_3207	COG1703	isobutyryl-CoA mutase activity
FORC066_3208	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC066_3208	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC066_3210	COG0596	Alpha beta hydrolase
FORC066_3212	COG0840	transmembrane signaling receptor activity
FORC066_3214	COG0735	belongs to the Fur family
FORC066_3218	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC066_3219	COG1263	PTS System
FORC066_3219	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC066_3219	COG2190	(PTS) system
FORC066_3220	COG0363	glucosamine-6-phosphate deaminase activity
FORC066_3221	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC066_3222	COG1846	Transcriptional regulator
FORC066_3222	COG1940	carbohydrate kinase activity
FORC066_3224	COG0647	UMP catabolic process
FORC066_3225	COG0367	asparagine synthase
FORC066_3226	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC066_3227	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC066_3228	COG1702	phosphate starvation-inducible protein PhoH
FORC066_3229	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC066_3230	COG4535	Mg2 and Co2 transporter CorC
FORC066_3231	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC066_3234	COG0765	amino acid transport
FORC066_3235	COG0765	amino acid transport
FORC066_3236	COG1126	abc transporter atp-binding protein
FORC066_3239	COG2888	peptidyl-tyrosine sulfation
FORC066_3241	COG0495	leucyl-tRNA aminoacylation
FORC066_3242	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC066_3243	COG1466	dna polymerase III delta subunit
FORC066_3244	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC066_3245	COG0799	negative regulation of ribosome biogenesis
FORC066_3247	COG0768	penicillin binding
FORC066_3248	COG0772	Belongs to the SEDS family
FORC066_3249	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC066_3250	COG1686	Belongs to the peptidase S11 family
FORC066_3251	COG2921	Belongs to the UPF0250 family
FORC066_3252	COG0321	lipoyl(octanoyl) transferase activity
FORC066_3253	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC066_3254	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC066_3255	COG3706	GGDEF domain
FORC066_3258	COG1278	Cold shock
FORC066_3259	COG2197	response regulator
FORC066_3261	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC066_3264	COG5265	(ABC) transporter
FORC066_3267	COG2986	histidine ammonia-lyase
FORC066_3268	COG2850	peptidyl-arginine hydroxylation
FORC066_3275	COG5002	protein histidine kinase activity
FORC066_3279	COG0656	L-ascorbic acid biosynthetic process
FORC066_3282	COG1902	pentaerythritol trinitrate reductase activity
FORC066_3284	COG0582	viral genome integration into host DNA
FORC066_3314	COG5410	chromosome segregation
FORC066_3315	COG3728	DNA packaging
FORC066_3315	COG5484	DNA packaging
FORC066_3320	COG3772	lysozyme
FORC066_3351	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC066_3362	COG0582	viral genome integration into host DNA
FORC066_3363	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC066_3364	COG2501	S4 domain
FORC066_3365	COG0215	cysteine-tRNA ligase activity
FORC066_3366	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC066_3367	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC066_3368	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC066_3369	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC066_3370	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC066_3371	COG4181	ATPase activity
FORC066_3372	COG2755	lipolytic protein G-D-S-L family
FORC066_3373	COG0300	oxidoreductase activity
FORC066_3374	COG3118	belongs to the thioredoxin family
FORC066_3375	COG0330	HflC and HflK could
FORC066_3376	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC066_3377	COG0789	Transcriptional regulator
FORC066_3378	COG2217	Heavy metal translocating P-type atpase
FORC066_3379	COG3735	TraB family
FORC066_3381	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC066_3382	COG0737	Belongs to the 5'-nucleotidase family
FORC066_3384	COG2223	nitrite transmembrane transporter activity
FORC066_3385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC066_3385	COG4651	solute:proton antiporter activity
FORC066_3386	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC066_3391	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC066_3392	COG0438	transferase activity, transferring glycosyl groups
FORC066_3393	COG1442	glycosyl transferase family 8
FORC066_3393	COG1216	Glycosyl transferase, family 2
FORC066_3394	COG1216	Glycosyl transferase, family 2
FORC066_3394	COG1442	glycosyl transferase family 8
FORC066_3395	COG2244	polysaccharide biosynthetic process
FORC066_3396	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC066_3397	COG0563	adenylate kinase activity
FORC066_3399	COG0326	Molecular chaperone. Has ATPase activity
FORC066_3400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC066_3401	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC066_3403	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC066_3407	COG3264	Mechanosensitive ion channel
FORC066_3407	COG1196	nuclear chromosome segregation
FORC066_3408	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC066_3409	COG1309	transcriptional regulator
FORC066_3410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_3411	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC066_3414	COG3457	Alanine racemase
FORC066_3415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC066_3418	COG0254	rRNA binding
FORC066_3419	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC066_3420	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC066_3421	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC066_3427	COG3695	enzyme binding
FORC066_3428	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC066_3430	COG1946	Acyl-CoA thioesterase
FORC066_3431	COG0004	ammonium transporteR
FORC066_3432	COG0347	Belongs to the P(II) protein family
FORC066_3433	COG1132	(ABC) transporter
FORC066_3434	COG1132	(ABC) transporter
FORC066_3435	COG1522	sequence-specific DNA binding
FORC066_3437	COG0561	phosphatase activity
FORC066_3438	COG4533	DNA binding
FORC066_3439	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC066_3440	COG0824	Thioesterase
FORC066_3441	COG1555	photosystem II stabilization
FORC066_3442	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC066_3444	COG0776	regulation of translation
FORC066_3445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC066_3447	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC066_3448	COG0740	serine-type endopeptidase activity
FORC066_3450	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC066_3451	COG0271	Belongs to the BolA IbaG family
FORC066_3452	COG3056	Lipoprotein
FORC066_3453	COG2223	nitrite transmembrane transporter activity
FORC066_3457	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC066_3458	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC066_3459	COG1845	cytochrome c oxidase, subunit III
FORC066_3460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FORC066_3461	COG0109	protoheme IX farnesyltransferase activity
FORC066_3462	COG2814	Major facilitator Superfamily
FORC066_3463	COG1666	GTP binding
FORC066_3465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC066_3467	COG0301	tRNA thio-modification
FORC066_3467	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC066_3468	COG1722	exodeoxyribonuclease VII activity
FORC066_3469	COG0142	geranyltranstransferase activity
FORC066_3470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC066_3471	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC066_3472	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC066_3473	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC066_3474	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC066_3475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC066_3475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC066_3476	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC066_3478	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC066_3479	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC066_3480	COG1862	Preprotein translocase
FORC066_3481	COG0343	queuine tRNA-ribosyltransferase activity
FORC066_3483	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC066_3484	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FORC066_3485	COG0450	alkyl hydroperoxide reductase
FORC066_3488	COG0366	Alpha amylase catalytic
FORC066_3492	COG5002	protein histidine kinase activity
FORC066_3493	COG0745	RESPONSE REGULATOR receiver
FORC066_3494	COG0420	3'-5' exonuclease activity
FORC066_3495	COG0419	ATPase involved in DNA repair
FORC066_3496	COG1940	carbohydrate kinase activity
FORC066_3497	COG2974	May be involved in recombination
FORC066_3498	COG3123	guanosine phosphorylase activity
FORC066_3500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC066_3506	COG2226	methyltransferase
FORC066_3509	COG3459	Glycosyltransferase 36 associated
FORC066_3513	COG2188	Transcriptional regulator
FORC066_3514	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FORC066_3515	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC066_3517	COG1073	alpha beta
FORC066_3518	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC066_3519	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC066_3520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC066_3524	COG2964	Protein conserved in bacteria
FORC066_3528	COG2991	Protein conserved in bacteria
FORC066_3529	COG1477	protein flavinylation
FORC066_3530	COG2871	sodium ion transport
FORC066_3531	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC066_3532	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC066_3533	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC066_3534	COG1805	sodium ion transport
FORC066_3535	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC066_3536	COG3034	peptidoglycan biosynthetic process
FORC066_3537	COG0121	glutamine amidotransferase
FORC066_3538	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC066_3539	COG1960	acyl-CoA dehydrogenase activity
FORC066_3540	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
FORC066_3543	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FORC066_3545	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FORC066_3546	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FORC066_3547	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FORC066_3548	COG0235	Class ii aldolase
FORC066_3549	COG0436	Aminotransferase
FORC066_3552	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC066_3554	COG0765	amino acid transport
FORC066_3555	COG0765	amino acid transport
FORC066_3563	COG2814	Major facilitator Superfamily
FORC066_3564	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FORC066_3566	COG1846	Transcriptional regulator
FORC066_3567	COG1538	Outer membrane efflux protein
FORC066_3568	COG1566	PFAM secretion protein HlyD family protein
FORC066_3569	COG2814	Major facilitator Superfamily
FORC066_3570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC066_3571	COG3118	belongs to the thioredoxin family
FORC066_3572	COG3148	PFAM DTW domain containing protein
FORC066_3573	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC066_3573	COG1042	CoA-binding domain protein
FORC066_3573	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC066_3574	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC066_3575	COG5544	Lipoprotein
FORC066_3576	COG0542	response to heat
FORC066_3577	COG1496	oxidoreductase activity
FORC066_3578	COG0564	pseudouridine synthase activity
FORC066_3579	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC066_3580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC066_3581	COG0077	Prephenate dehydratase
FORC066_3581	COG1605	Chorismate mutase
FORC066_3582	COG0287	Prephenate dehydrogenase
FORC066_3582	COG1605	Chorismate mutase
FORC066_3583	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC066_3584	COG3279	Response regulator of the LytR AlgR family
FORC066_3586	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC066_3587	COG3137	Salt-induced outer membrane protein
FORC066_3588	COG0335	large ribosomal subunit rRNA binding
FORC066_3589	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC066_3590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC066_3591	COG0228	four-way junction DNA binding
FORC066_3593	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC066_3594	COG4137	Cytochrome C assembly protein
FORC066_3595	COG4536	flavin adenine dinucleotide binding
FORC066_3596	COG1854	S-ribosylhomocysteine lyase activity
FORC066_3597	COG2918	glutathione biosynthetic process
FORC066_3598	COG1238	metal cluster binding
FORC066_3599	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC066_3600	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC066_3601	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC066_3602	COG2137	regulation of response to DNA damage stimulus
FORC066_3603	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC066_3608	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC066_3609	COG3958	Transketolase
FORC066_3610	COG3959	Transketolase, thiamine diphosphate binding domain
FORC066_3611	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_3612	COG1129	ABC transporter
FORC066_3614	COG1879	ABC-type sugar transport system periplasmic component
FORC066_3617	COG3381	protein complex oligomerization
FORC066_3618	COG3302	dmso reductase anchor subunit
FORC066_3619	COG0437	4 iron, 4 sulfur cluster binding
FORC066_3620	COG0243	molybdopterin cofactor binding
FORC066_3621	COG1454	alcohol dehydrogenase
FORC066_3622	COG0235	Class ii aldolase
FORC066_3623	COG0738	Major facilitator superfamily
FORC066_3624	COG0738	Major facilitator superfamily
FORC066_3626	COG1070	Carbohydrate kinase
FORC066_3628	COG1349	DNA-binding transcription factor activity
FORC066_3630	COG1349	DNA-binding transcription factor activity
FORC066_3632	COG1129	ABC transporter
FORC066_3633	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_3635	COG3623	hexulose-6-phosphate isomerase
FORC066_3636	COG1070	Carbohydrate kinase
FORC066_3637	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC066_3637	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC066_3640	COG4177	L-phenylalanine transmembrane transporter activity
FORC066_3641	COG1137	ATPase activity
FORC066_3642	COG0410	ABC transporter
FORC066_3653	COG0640	Transcriptional regulator
FORC066_3654	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC066_3658	COG3665	Urea carboxylase-associated protein
FORC066_3659	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC066_3660	COG1126	abc transporter atp-binding protein
FORC066_3661	COG0765	amino acid transport
FORC066_3662	COG0765	amino acid transport
FORC066_3663	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_3664	COG3048	D-serine ammonia-lyase activity
FORC066_3665	COG2610	gluconate transmembrane transporter activity
FORC066_3667	COG0583	DNA-binding transcription factor activity
FORC066_3671	COG1028	Short-chain dehydrogenase reductase Sdr
FORC066_3675	COG1538	Outer membrane efflux protein
FORC066_3677	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_3683	COG3539	Fimbrial protein
FORC066_3684	COG3539	Fimbrial protein
FORC066_3686	COG3121	Chaperone
FORC066_3687	COG3188	usher protein
FORC066_3693	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC066_3694	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC066_3695	COG1388	LysM domain
FORC066_3695	COG4942	peptidase
FORC066_3696	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC066_3697	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORC066_3698	COG0585	pseudouridine synthase activity
FORC066_3699	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC066_3701	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC066_3703	COG0765	amino acid transport
FORC066_3706	COG0529	Catalyzes the synthesis of activated sulfate
FORC066_3707	COG2895	sulfate adenylyltransferase (ATP) activity
FORC066_3708	COG0175	sulfate reduction
FORC066_3709	COG1648	precorrin-2 dehydrogenase activity
FORC066_3709	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC066_3710	COG2234	aminopeptidase activity
FORC066_3713	COG0175	sulfate reduction
FORC066_3714	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC066_3715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC066_3716	COG0720	synthase
FORC066_3717	COG0602	queuosine metabolic process
FORC066_3725	COG0148	phosphopyruvate hydratase activity
FORC066_3726	COG0504	CTP synthase activity
FORC066_3727	COG3956	TIGRFAM MazG family protein
FORC066_3728	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC066_3729	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC066_3730	COG2205	protein histidine kinase activity
FORC066_3730	COG3437	response regulator, receiver
FORC066_3730	COG3850	Histidine kinase
FORC066_3730	COG4999	Histidine kinase
FORC066_3731	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC066_3733	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC066_3734	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC066_3736	COG2860	membrane
FORC066_3737	COG0316	Belongs to the HesB IscA family
FORC066_3740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORC066_3741	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC066_3742	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC066_3743	COG1120	ATPase activity
FORC066_3744	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC066_3745	COG1643	Atp-dependent helicase
FORC066_3746	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FORC066_3747	COG1489	DNA binding
FORC066_3751	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC066_3752	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC066_3753	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORC066_3754	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FORC066_3755	COG0726	polysaccharide deacetylase
FORC066_3756	COG0842	Transport permease protein
FORC066_3757	COG1131	(ABC) transporter
FORC066_3758	COG0288	reversible hydration of carbon dioxide
FORC066_3759	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC066_3761	COG2132	Multicopper oxidase
FORC066_3763	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FORC066_3764	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FORC066_3771	COG0697	spore germination
FORC066_3772	COG3112	Uncharacterised protein family (UPF0231)
FORC066_3777	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC066_3778	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC066_3779	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC066_3783	COG1113	amino acid transport
FORC066_3784	COG3725	Membrane protein required for beta-lactamase induction
FORC066_3787	COG4969	Belongs to the N-Me-Phe pilin family
FORC066_3788	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC066_3789	COG1459	type II secretion system
FORC066_3790	COG0516	GMP reductase activity
FORC066_3792	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FORC066_3793	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC066_3794	COG0494	nUDIX hydrolase
FORC066_3795	COG0653	protein targeting
FORC066_3800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC066_3801	COG0849	cell division
FORC066_3804	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC066_3805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC066_3806	COG0772	Belongs to the SEDS family
FORC066_3808	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC066_3809	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC066_3810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORC066_3811	COG0768	penicillin binding
FORC066_3812	COG3116	cell division
FORC066_3813	COG0275	rRNA processing
FORC066_3814	COG2001	Belongs to the MraZ family
FORC066_3818	COG0028	Belongs to the TPP enzyme family
FORC066_3819	COG1022	Amp-dependent synthetase and ligase
FORC066_3821	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC066_3822	COG0473	3-isopropylmalate dehydrogenase activity
FORC066_3823	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORC066_3826	COG3033	Beta-eliminating lyase
FORC066_3827	COG0814	amino acid
FORC066_3828	COG2814	Major facilitator Superfamily
FORC066_3830	COG1882	Formate acetyltransferase
FORC066_3831	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC066_3832	COG4533	DNA binding
FORC066_3835	COG4143	(ABC) transporter
FORC066_3836	COG1178	ABC-type Fe3 transport system permease component
FORC066_3838	COG0586	Pfam SNARE associated Golgi protein
FORC066_3839	COG0417	DNA replication proofreading
FORC066_3841	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC066_3843	COG1388	LysM domain
FORC066_3843	COG1470	cell adhesion involved in biofilm formation
FORC066_3844	COG0564	pseudouridine synthase activity
FORC066_3845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC066_3846	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC066_3848	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC066_3849	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC066_3850	COG2967	ApaG domain
FORC066_3851	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC066_3852	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC066_3853	COG3610	response to peptide
FORC066_3854	COG2966	Psort location CytoplasmicMembrane, score
FORC066_3856	COG1280	lysine exporter protein (LysE YggA)
FORC066_3857	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC066_3859	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORC066_3860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC066_3861	COG1047	Peptidyl-prolyl cis-trans
FORC066_3862	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC066_3863	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC066_3864	COG0196	riboflavin kinase activity
FORC066_3865	COG0268	Binds directly to 16S ribosomal RNA
FORC066_3866	COG0583	DNA-binding transcription factor activity
FORC066_3867	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC066_3868	COG0484	heat shock protein binding
FORC066_3870	COG1584	GPR1 FUN34 yaaH family protein
FORC066_3873	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC066_3874	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC066_3875	COG3022	response to hydroperoxide
FORC066_3877	COG0083	homoserine kinase activity
FORC066_3880	COG0745	RESPONSE REGULATOR receiver
FORC066_3881	COG3045	CreA protein
FORC066_3882	COG3708	Transcriptional regulator
FORC066_3882	COG2207	Transcriptional regulator
FORC066_3883	COG0406	alpha-ribazole phosphatase activity
FORC066_3884	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC066_3885	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC066_3886	COG0741	lytic transglycosylase activity
FORC066_3887	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC066_3889	COG2199	diguanylate cyclase activity
FORC066_3890	COG2885	chlorophyll binding
FORC066_3891	COG0488	(ABC) transporter
FORC066_3893	COG0604	alcohol dehydrogenase
FORC066_3896	COG0560	Phosphoserine phosphatase
FORC066_3897	COG3726	membrane protein affecting hemolysin expression
FORC066_3898	COG0813	purine-nucleoside phosphorylase activity
FORC066_3899	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC066_3900	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC066_3903	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC066_3905	COG0084	hydrolase, TatD family'
FORC066_3906	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC066_3908	COG2823	Periplasmic or secreted lipoprotein
FORC066_3909	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FORC066_3910	COG0456	acetyltransferase
FORC066_3911	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FORC066_3912	COG2813	Specifically methylates the guanine in position
FORC066_3913	COG0667	Aldo Keto reductase
FORC066_3918	COG4772	TonB-dependent receptor
FORC066_3927	COG3284	Transcriptional regulator
FORC066_3933	COG2192	nodulation
FORC066_3935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC066_3935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC066_3935	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FORC066_3936	COG1461	Dihydroxyacetone kinase
FORC066_3937	COG2376	Dihydroxyacetone kinase
FORC066_3939	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC066_3940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_3941	COG2235	arginine
FORC066_3947	COG0859	PFAM glycosyl transferase family 9
FORC066_3949	COG1070	Carbohydrate kinase
FORC066_3950	COG2390	Transcriptional regulator
FORC066_3951	COG1129	ABC transporter
FORC066_3952	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_3953	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_3954	COG1879	ABC-type sugar transport system periplasmic component
FORC066_3955	COG1830	Aldolase
FORC066_3956	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC066_3965	COG0514	ATP-dependent DNA helicase (RecQ)
FORC066_3968	COG2801	Transposase and inactivated derivatives
FORC066_3971	COG2003	Belongs to the UPF0758 family
FORC066_3977	COG2378	regulation of single-species biofilm formation
FORC066_3979	COG3596	GTP binding
FORC066_3989	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC066_3993	COG0582	viral genome integration into host DNA
FORC066_3994	COG0795	lipopolysaccharide-transporting ATPase activity
FORC066_3995	COG0795	lipopolysaccharide-transporting ATPase activity
FORC066_3996	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC066_3997	COG2927	DNA polymerase III (CHI subunit)
FORC066_4001	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FORC066_4003	COG2731	YhcH YjgK YiaL family protein
FORC066_4005	COG0601	transmembrane transport
FORC066_4006	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC066_4007	COG0444	Belongs to the ABC transporter superfamily
FORC066_4008	COG4608	Belongs to the ABC transporter superfamily
FORC066_4011	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC066_4012	COG0583	DNA-binding transcription factor activity
FORC066_4017	COG2188	Transcriptional regulator
FORC066_4018	COG3624	Phosphonate C-P lyase system protein PhnG
FORC066_4019	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FORC066_4020	COG3626	phosphonate metabolism
FORC066_4021	COG3627	carbon phosphorus lyase activity
FORC066_4022	COG4107	phosphonate C-P lyase system protein PhnK
FORC066_4023	COG4778	phosphonate C-P lyase system protein PhnL
FORC066_4024	COG3454	Phosphonate metabolism
FORC066_4025	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FORC066_4026	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FORC066_4027	COG0702	epimerase
FORC066_4030	COG3787	Belongs to the UPF0306 family
FORC066_4032	COG3842	ATPase activity
FORC066_4033	COG0395	ABC-type sugar transport system, permease component
FORC066_4034	COG1175	transmembrane transport
FORC066_4035	COG1653	transport
FORC066_4039	COG1982	Orn Lys Arg decarboxylase major
FORC066_4040	COG0531	amino acid
FORC066_4041	COG2827	Endonuclease containing a URI domain
FORC066_4042	COG3153	acetyltransferase
FORC066_4043	COG3154	lipid carrier protein
FORC066_4044	COG0826	peptidase U32
FORC066_4045	COG0826	peptidase U32
FORC066_4046	COG3681	Belongs to the UPF0597 family
FORC066_4047	COG0814	amino acid
FORC066_4049	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC066_4050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC066_4051	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC066_4054	COG0513	Belongs to the DEAD box helicase family
FORC066_4056	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC066_4057	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC066_4058	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC066_4059	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC066_4060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC066_4061	COG0195	Participates in both transcription termination and antitermination
FORC066_4062	COG0779	Required for maturation of 30S ribosomal subunits
FORC066_4063	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC066_4064	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC066_4065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC066_4067	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC066_4068	COG1534	Rna-binding protein
FORC066_4070	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC066_4071	COG0745	RESPONSE REGULATOR receiver
FORC066_4072	COG0642	Histidine kinase
FORC066_4073	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC066_4074	COG0697	spore germination
FORC066_4075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC066_4076	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC066_4077	COG0142	geranyltranstransferase activity
FORC066_4080	COG3423	Transcriptional regulator
FORC066_4081	COG0039	L-malate dehydrogenase activity
FORC066_4082	COG1438	arginine binding
FORC066_4084	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC066_4085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC066_4088	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC066_4089	COG2105	PFAM AIG2 family protein
FORC066_4090	COG2911	Protein conserved in bacteria
FORC066_4092	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC066_4093	COG1253	flavin adenine dinucleotide binding
FORC066_4095	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC066_4096	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC066_4097	COG0737	Belongs to the 5'-nucleotidase family
FORC066_4099	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC066_4101	COG3061	Opacity-associated protein A
FORC066_4103	COG0359	binds to the 23S rRNA
FORC066_4104	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FORC066_4105	COG2965	DNA replication, synthesis of RNA primer
FORC066_4106	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC066_4108	COG1073	alpha beta
FORC066_4109	COG3650	response to hydrogen peroxide
FORC066_4110	COG1960	acyl-CoA dehydrogenase activity
FORC066_4112	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC066_4113	COG0557	exoribonuclease II activity
FORC066_4114	COG1959	2 iron, 2 sulfur cluster binding
FORC066_4115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC066_4116	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC066_4117	COG0330	HflC and HflK could
FORC066_4118	COG0330	HflC and HflK could
FORC066_4119	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC066_4120	COG1923	regulation of RNA biosynthetic process
FORC066_4121	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORC066_4122	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC066_4123	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC066_4124	COG0802	atpase or kinase
FORC066_4125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC066_4125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC066_4126	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC066_4127	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC066_4128	COG1162	GTPase activity
FORC066_4129	COG0688	phosphatidylethanolamine metabolic process
FORC066_4130	COG3264	Mechanosensitive ion channel
FORC066_4130	COG1511	domain protein
FORC066_4131	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC066_4132	COG1053	succinate dehydrogenase
FORC066_4133	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC066_4134	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC066_4135	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC066_4140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC066_4145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC066_4149	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC066_4151	COG4232	protein-disulfide reductase activity
FORC066_4152	COG1929	Belongs to the glycerate kinase type-1 family
FORC066_4153	COG1309	transcriptional regulator
FORC066_4154	COG1882	Formate acetyltransferase
FORC066_4155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC066_4156	COG0814	amino acid
FORC066_4159	COG3721	Heme iron utilization protein
FORC066_4160	COG0702	epimerase
FORC066_4163	COG3720	iron ion transport
FORC066_4164	COG4558	Periplasmic binding protein
FORC066_4165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC066_4166	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC066_4167	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC066_4169	COG4774	siderophore transport
FORC066_4170	COG3264	Mechanosensitive ion channel
FORC066_4170	COG1511	domain protein
FORC066_4171	COG0612	Peptidase, M16
FORC066_4172	COG4178	(ABC) transporter
FORC066_4173	COG4771	TonB-dependent receptor
FORC066_4174	COG3712	iron ion homeostasis
FORC066_4179	COG0425	Belongs to the sulfur carrier protein TusA family
FORC066_4180	COG2391	methyltransferase activity
FORC066_4211	COG0784	Response regulator, receiver
FORC066_4211	COG2205	protein histidine kinase activity
FORC066_4212	COG2197	response regulator
FORC066_4213	COG1301	dicarboxylic acid transport
FORC066_4214	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC066_4215	COG3162	membrane
FORC066_4216	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC066_4219	COG0138	bifunctional purine biosynthesis protein purh
FORC066_4220	COG0151	Belongs to the GarS family
FORC066_4224	COG1515	deoxyribonuclease V activity
FORC066_4225	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC066_4226	COG2816	NAD+ diphosphatase activity
FORC066_4227	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC066_4230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC066_4231	COG2104	thiamine diphosphate biosynthetic process
FORC066_4232	COG2022	thiamine diphosphate biosynthetic process
FORC066_4234	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC066_4235	COG0085	RNA polymerase activity
FORC066_4236	COG0222	ribosome binding
FORC066_4237	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC066_4238	COG0081	regulation of translation
FORC066_4239	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC066_4240	COG0250	Participates in transcription elongation, termination and antitermination
FORC066_4242	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC066_4244	COG1072	(Pantothenic acid kinase))
FORC066_4245	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FORC066_4245	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FORC066_4248	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC066_4249	COG1739	Uncharacterized protein family UPF0029
FORC066_4250	COG0006	proline dipeptidase activity
FORC066_4251	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC066_4251	COG1024	Enoyl-CoA hydratase
FORC066_4252	COG0183	Belongs to the thiolase family
FORC066_4254	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FORC066_4258	COG0805	protein transport
FORC066_4259	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC066_4260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC066_4261	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC066_4263	COG2226	methyltransferase
FORC066_4264	COG1322	Protein conserved in bacteria
FORC066_4265	COG0586	Pfam SNARE associated Golgi protein
FORC066_4266	COG1966	Carbon starvation protein
FORC066_4269	COG0412	Dienelactone hydrolase
FORC066_4270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC066_4271	COG0583	DNA-binding transcription factor activity
FORC066_4273	COG0679	Auxin Efflux Carrier
FORC066_4274	COG0584	glycerophosphoryl diester phosphodiesterase
FORC066_4275	COG3842	ATPase activity
FORC066_4276	COG0395	ABC-type sugar transport system, permease component
FORC066_4277	COG1175	transmembrane transport
FORC066_4278	COG1653	transport
FORC066_4285	COG0410	ABC transporter
FORC066_4287	COG4177	L-phenylalanine transmembrane transporter activity
FORC066_4289	COG0683	leucine binding
FORC066_4292	COG2177	Part of the ABC transporter FtsEX involved in
FORC066_4293	COG2884	Cell division ATP-binding protein ftsE
FORC066_4294	COG0552	protein localization to endoplasmic reticulum
FORC066_4295	COG0742	ribosomal rna small subunit methyltransferase
FORC066_4296	COG3776	membrane
FORC066_4299	COG3714	YhhN family
FORC066_4300	COG2217	Heavy metal translocating P-type atpase
FORC066_4301	COG0425	Belongs to the sulfur carrier protein TusA family
FORC066_4302	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC066_4304	COG0247	lactate metabolic process
FORC066_4305	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FORC066_4306	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC066_4308	COG2271	Major facilitator Superfamily
FORC066_4309	COG0584	glycerophosphoryl diester phosphodiesterase
FORC066_4310	COG0561	phosphatase activity
FORC066_4311	COG2267	carboxylic ester hydrolase activity
FORC066_4313	COG1280	lysine exporter protein (LysE YggA)
FORC066_4314	COG1280	lysine exporter protein (LysE YggA)
FORC066_4315	COG0514	ATP-dependent DNA helicase (RecQ)
FORC066_4316	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FORC066_4317	COG2050	protein possibly involved in aromatic compounds catabolism
FORC066_4321	COG5564	TIM-barrel signal transduction protein
FORC066_4322	COG5441	Belongs to the UPF0261 family
FORC066_4324	COG0210	DNA helicase
FORC066_4325	COG1011	Hydrolase
FORC066_4326	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC066_4327	COG3159	Protein conserved in bacteria
FORC066_4328	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC066_4330	COG1965	Belongs to the frataxin family
FORC066_4331	COG3072	Adenylate cyclase
FORC066_4333	COG0181	hydroxymethylbilane synthase activity
FORC066_4334	COG1587	Uroporphyrinogen-III synthase
FORC066_4335	COG2959	enzyme of heme biosynthesis
FORC066_4336	COG3071	HemY protein
FORC066_4341	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC066_4342	COG2244	polysaccharide biosynthetic process
FORC066_4343	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC066_4344	COG0456	acetyltransferase
FORC066_4345	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC066_4346	COG1088	dTDP-glucose 4,6-dehydratase activity
FORC066_4347	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORC066_4348	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC066_4349	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FORC066_4352	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC066_4353	COG3118	belongs to the thioredoxin family
FORC066_4355	COG0248	Ppx GppA phosphatase
FORC066_4358	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC066_4361	COG3121	Chaperone
FORC066_4364	COG3121	Chaperone
FORC066_4369	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC066_4370	COG0583	DNA-binding transcription factor activity
FORC066_4373	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC066_4374	COG0129	dihydroxy-acid dehydratase activity
FORC066_4375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC066_4376	COG3978	acetolactate synthase activity
FORC066_4380	COG3085	chromosome segregation
FORC066_4381	COG0583	DNA-binding transcription factor activity
FORC066_4382	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_4383	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_4384	COG1129	ABC transporter
FORC066_4385	COG1879	ABC-type sugar transport system periplasmic component
FORC066_4387	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC066_4389	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC066_4391	COG1309	transcriptional regulator
FORC066_4392	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC066_4394	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC066_4394	COG0678	peroxiredoxin activity
FORC066_4395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC066_4403	COG1629	transport
FORC066_4404	COG0165	Argininosuccinate lyase
FORC066_4405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC066_4409	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC066_4411	COG0460	homoserine dehydrogenase
FORC066_4411	COG0527	aspartate kinase activity
FORC066_4412	COG0626	cystathionine gamma-synthase activity
FORC066_4413	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC066_4414	COG0254	rRNA binding
FORC066_4416	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC066_4417	COG1609	Transcriptional regulator
FORC066_4418	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC066_4419	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC066_4420	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC066_4421	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC066_4422	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC066_4423	COG3074	FtsZ-dependent cytokinesis
FORC066_4426	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC066_4427	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC066_4428	COG1494	fructose-1,6-bisphosphatase
FORC066_4429	COG2814	Major facilitator Superfamily
FORC066_4432	COG3152	Membrane
FORC066_4434	COG0149	triose-phosphate isomerase activity
FORC066_4436	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC066_4439	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC066_4440	COG3678	ATP-independent chaperone mediated protein folding
FORC066_4441	COG0745	RESPONSE REGULATOR receiver
FORC066_4442	COG2205	protein histidine kinase activity
FORC066_4443	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC066_4443	COG2169	Transcriptional regulator
FORC066_4444	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC066_4445	COG1045	serine acetyltransferase
FORC066_4446	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC066_4447	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC066_4448	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC066_4449	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC066_4450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC066_4451	COG4942	peptidase
FORC066_4452	COG2861	carbohydrate metabolic process
FORC066_4453	COG1063	alcohol dehydrogenase
FORC066_4454	COG0156	8-amino-7-oxononanoate synthase activity
FORC066_4455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC066_4456	COG0859	PFAM glycosyl transferase family 9
FORC066_4457	COG0859	PFAM glycosyl transferase family 9
FORC066_4458	COG1519	Transferase
FORC066_4460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC066_4461	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC066_4462	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC066_4463	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC066_4464	COG2003	Belongs to the UPF0758 family
FORC066_4465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC066_4466	COG0756	dUTP diphosphatase activity
FORC066_4467	COG1309	transcriptional regulator
FORC066_4468	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORC066_4469	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC066_4470	COG1561	YicC-like family, N-terminal region
FORC066_4473	COG5001	Diguanylate cyclase
FORC066_4474	COG1024	Enoyl-CoA hydratase
FORC066_4475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC066_4477	COG2860	membrane
FORC066_4478	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC066_4480	COG1758	RNA polymerase activity
FORC066_4481	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC066_4482	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC066_4483	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC066_4484	COG0786	glutamate:sodium symporter activity
FORC066_4485	COG2233	PERMEase
FORC066_4486	COG2982	Protein involved in outer membrane biogenesis
FORC066_4491	COG3423	Transcriptional regulator
FORC066_4492	COG0456	acetyltransferase
FORC066_4493	COG1490	D-aminoacyl-tRNA deacylase activity
FORC066_4494	COG1295	ribonuclease BN
FORC066_4495	COG1011	Hydrolase
FORC066_4498	COG3852	Histidine kinase
FORC066_4500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC066_4501	COG3078	GTPase activator activity
FORC066_4502	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC066_4504	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC066_4504	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC066_4506	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC066_4507	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC066_4508	COG3084	Protein conserved in bacteria
FORC066_4510	COG1763	Mo-molybdopterin cofactor biosynthetic process
FORC066_4511	COG2186	Transcriptional regulator
FORC066_4512	COG0477	Major facilitator Superfamily
FORC066_4513	COG1609	Transcriptional regulator
FORC066_4514	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC066_4515	COG1879	ABC-type sugar transport system periplasmic component
FORC066_4516	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC066_4518	COG1869	D-ribose catabolic process
FORC066_4519	COG3158	transport of potassium into the cell
FORC066_4520	COG0714	Associated with various cellular activities
FORC066_4521	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC066_4523	COG2502	aspartate--ammonia ligase
FORC066_4524	COG1522	sequence-specific DNA binding
FORC066_4525	COG0716	FMN binding
FORC066_4527	COG0445	tRNA wobble uridine modification
FORC066_4528	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC066_4529	COG3312	ion transport
FORC066_4530	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC066_4532	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC066_4533	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC066_4534	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC066_4535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC066_4536	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC066_4537	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC066_4538	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC066_4540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC066_4541	COG0573	inorganic phosphate transmembrane transporter activity
FORC066_4542	COG0581	inorganic phosphate transmembrane transporter activity
FORC066_4544	COG0704	Plays a role in the regulation of phosphate uptake
FORC066_4546	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC066_4547	COG0765	amino acid transport
FORC066_4548	COG0765	amino acid transport
FORC066_4549	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC066_4550	COG2252	PERMEase
FORC066_4552	COG4566	intracellular signal transduction
FORC066_4553	COG4191	Histidine kinase
FORC066_4554	COG0431	NADPH-dependent FMN reductase
FORC066_4555	COG0840	transmembrane signaling receptor activity
FORC066_4556	COG2011	ABC-type metal ion transport system permease component
FORC066_4559	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC066_4560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORC066_4561	COG0706	membrane insertase activity
FORC066_4562	COG0594	ribonuclease P activity
FORC066_4563	COG0230	Belongs to the bacterial ribosomal protein bL34 family