locus-tag	class	description
BB936_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BB936_00010	COG0592	DNA-directed DNA polymerase activity
BB936_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BB936_00020	COG0187	DNA topoisomerase II activity
BB936_00025	COG0561	phosphatase activity
BB936_00030	COG2423	ornithine cyclodeaminase activity
BB936_00040	COG0823	Involved in the tonB-independent uptake of proteins
BB936_00045	COG5645	(Lipo)protein
BB936_00065	COG2985	domain, Protein
BB936_00065	COG0569	domain protein
BB936_00070	COG3977	Valine--pyruvate aminotransferase
BB936_00075	COG0366	Alpha amylase catalytic
BB936_00080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB936_00110	COG0456	acetyltransferase
BB936_00115	COG2818	Glycosylase
BB936_00120	COG0752	glycyl-tRNA synthetase alpha subunit
BB936_00125	COG0751	glycine-tRNA ligase activity
BB936_00135	COG2213	PTS system mannitol-specific
BB936_00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_00140	COG0246	Mannitol dehydrogenase
BB936_00145	COG3722	fumarate hydratase activity
BB936_00155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB936_00175	COG2258	MOSC domain
BB936_00180	COG0840	transmembrane signaling receptor activity
BB936_00185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB936_00190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BB936_00195	COG0243	molybdopterin cofactor binding
BB936_00195	COG3383	formate dehydrogenase (NAD+) activity
BB936_00200	COG0243	molybdopterin cofactor binding
BB936_00200	COG3383	formate dehydrogenase (NAD+) activity
BB936_00205	COG0437	4 iron, 4 sulfur cluster binding
BB936_00210	COG2864	formate dehydrogenase
BB936_00215	COG3058	Necessary for formate dehydrogenase activity
BB936_00220	COG1921	L-seryl-tRNASec selenium transferase activity
BB936_00225	COG3276	selenocysteine insertion sequence binding
BB936_00235	COG3274	enterobacterial common antigen metabolic process
BB936_00250	COG3121	Chaperone
BB936_00255	COG1070	Carbohydrate kinase
BB936_00260	COG2115	Belongs to the xylose isomerase family
BB936_00265	COG4213	ABC transporter substrate-binding protein
BB936_00275	COG4214	carbohydrate transport
BB936_00280	COG2207	Transcriptional regulator
BB936_00280	COG1609	Transcriptional regulator
BB936_00285	COG0582	viral genome integration into host DNA
BB936_00320	COG3177	Filamentation induced by cAMP protein fic
BB936_00345	COG2986	histidine ammonia-lyase
BB936_00350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BB936_00370	COG1482	cell wall glycoprotein biosynthetic process
BB936_00375	COG2723	6-phospho-beta-galactosidase activity
BB936_00390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BB936_00395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BB936_00405	COG1447	Phosphotransferase system cellobiose-specific component IIA
BB936_00415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BB936_00420	COG1024	Enoyl-CoA hydratase
BB936_00425	COG5001	Diguanylate cyclase
BB936_00505	COG3561	AntA/AntB antirepressor
BB936_00525	COG0582	viral genome integration into host DNA
BB936_00530	COG1561	YicC-like family, N-terminal region
BB936_00535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BB936_00540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BB936_00545	COG1309	transcriptional regulator
BB936_00550	COG0756	dUTP diphosphatase activity
BB936_00555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BB936_00560	COG2003	Belongs to the UPF0758 family
BB936_00565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BB936_00570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BB936_00575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB936_00580	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BB936_00590	COG1519	Transferase
BB936_00595	COG0859	PFAM glycosyl transferase family 9
BB936_00600	COG0859	PFAM glycosyl transferase family 9
BB936_00605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB936_00610	COG0156	8-amino-7-oxononanoate synthase activity
BB936_00615	COG1063	alcohol dehydrogenase
BB936_00630	COG2861	carbohydrate metabolic process
BB936_00635	COG4942	peptidase
BB936_00640	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BB936_00645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BB936_00650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB936_00655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BB936_00660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BB936_00665	COG1045	serine acetyltransferase
BB936_00670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BB936_00675	COG2169	Transcriptional regulator
BB936_00675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB936_00680	COG2205	protein histidine kinase activity
BB936_00685	COG0745	RESPONSE REGULATOR receiver
BB936_00690	COG3678	ATP-independent chaperone mediated protein folding
BB936_00695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BB936_00705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BB936_00715	COG0149	triose-phosphate isomerase activity
BB936_00725	COG3152	Membrane
BB936_00745	COG2814	Major facilitator Superfamily
BB936_00760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB936_00765	COG3074	FtsZ-dependent cytokinesis
BB936_00770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BB936_00775	COG1575	Belongs to the MenA family. Type 1 subfamily
BB936_00780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BB936_00785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BB936_00790	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BB936_00795	COG1609	Transcriptional regulator
BB936_00800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BB936_00805	COG0254	rRNA binding
BB936_00810	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BB936_00815	COG0626	cystathionine gamma-synthase activity
BB936_00820	COG0460	homoserine dehydrogenase
BB936_00820	COG0527	aspartate kinase activity
BB936_00830	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BB936_00840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BB936_00845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BB936_00850	COG0165	Argininosuccinate lyase
BB936_00855	COG1629	transport
BB936_00895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB936_00900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB936_00900	COG0678	peroxiredoxin activity
BB936_00910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB936_00915	COG1309	transcriptional regulator
BB936_00925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BB936_00935	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BB936_00975	COG1879	ABC-type sugar transport system periplasmic component
BB936_00980	COG1129	ABC transporter
BB936_00985	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB936_00990	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB936_00995	COG0583	DNA-binding transcription factor activity
BB936_01000	COG3085	chromosome segregation
BB936_01015	COG3978	acetolactate synthase activity
BB936_01020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB936_01025	COG0129	dihydroxy-acid dehydratase activity
BB936_01045	COG0583	DNA-binding transcription factor activity
BB936_01050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BB936_01075	COG3121	Chaperone
BB936_01095	COG3121	Chaperone
BB936_01110	COG1609	Transcriptional regulator
BB936_01135	COG3328	transposase activity
BB936_01145	COG3210	domain, Protein
BB936_01150	COG2831	hemolysin activation secretion protein
BB936_01175	COG3851	Histidine kinase
BB936_01180	COG2197	response regulator
BB936_01185	COG2194	sulfuric ester hydrolase activity
BB936_01190	COG1764	response to oxidative stress
BB936_01200	COG0747	negative chemotaxis
BB936_01205	COG0601	transmembrane transport
BB936_01210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB936_01215	COG0444	Belongs to the ABC transporter superfamily
BB936_01220	COG4608	Belongs to the ABC transporter superfamily
BB936_01225	COG2194	sulfuric ester hydrolase activity
BB936_01245	COG1192	Involved in chromosome partitioning
BB936_01250	COG1215	transferase activity, transferring glycosyl groups
BB936_01255	COG1215	transferase activity, transferring glycosyl groups
BB936_01260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BB936_01265	COG3118	belongs to the thioredoxin family
BB936_01265	COG0457	Tetratricopeptide repeat
BB936_01275	COG2200	EAL domain
BB936_01275	COG2199	diguanylate cyclase activity
BB936_01280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BB936_01295	COG1301	dicarboxylic acid transport
BB936_01300	COG0612	Peptidase, M16
BB936_01305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB936_01310	COG1942	4-Oxalocrotonate Tautomerase
BB936_01315	COG2200	EAL domain
BB936_01325	COG2134	cdp-diacylglycerol pyrophosphatase
BB936_01330	COG1295	ribonuclease BN
BB936_01340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB936_01345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BB936_01355	COG0742	ribosomal rna small subunit methyltransferase
BB936_01370	COG0589	response to stress
BB936_01385	COG0306	phosphate transporter
BB936_01390	COG2081	HI0933 family
BB936_01465	COG1301	dicarboxylic acid transport
BB936_01480	COG3799	methylaspartate ammonia-lyase activity
BB936_01485	COG4865	methylaspartate mutase activity
BB936_01505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BB936_01505	COG1648	precorrin-2 dehydrogenase activity
BB936_01510	COG0583	DNA-binding transcription factor activity
BB936_01515	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BB936_01515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BB936_01525	COG0561	phosphatase activity
BB936_01535	COG0583	DNA-binding transcription factor activity
BB936_01540	COG2814	Major facilitator Superfamily
BB936_01550	COG3718	enzyme involved in inositol metabolism
BB936_01560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB936_01570	COG0673	inositol 2-dehydrogenase activity
BB936_01575	COG1082	Xylose isomerase domain protein TIM barrel
BB936_01580	COG1247	-acetyltransferase
BB936_01585	COG1741	Belongs to the pirin family
BB936_01590	COG1609	Transcriptional regulator
BB936_01595	COG2610	gluconate transmembrane transporter activity
BB936_01600	COG3265	gluconokinase activity
BB936_01605	COG2095	MarC family integral membrane protein
BB936_01610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BB936_01630	COG3275	phosphorelay sensor kinase activity
BB936_01635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BB936_01640	COG1523	belongs to the glycosyl hydrolase 13 family
BB936_01650	COG0297	glycogen (starch) synthase activity
BB936_01655	COG0058	SHG alpha-glucan phosphorylase activity
BB936_01660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BB936_01675	COG1349	DNA-binding transcription factor activity
BB936_01680	COG0705	Rhomboid family
BB936_01695	COG2909	trisaccharide binding
BB936_01700	COG0058	SHG alpha-glucan phosphorylase activity
BB936_01705	COG1640	4-alpha-glucanotransferase
BB936_01715	COG0316	Belongs to the HesB IscA family
BB936_01715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BB936_01725	COG0596	Alpha beta hydrolase
BB936_01745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BB936_01750	COG1918	ferrous iron import across plasma membrane
BB936_01755	COG2183	response to ionizing radiation
BB936_01780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB936_01785	COG0745	RESPONSE REGULATOR receiver
BB936_01795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BB936_01805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BB936_01810	COG1011	Hydrolase
BB936_01820	COG0494	nUDIX hydrolase
BB936_01825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BB936_01850	COG4796	Type ii and iii secretion system protein
BB936_01855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BB936_01875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB936_01885	COG0180	Tryptophanyl-tRNA synthetase
BB936_01890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BB936_01890	COG1648	precorrin-2 dehydrogenase activity
BB936_01900	COG2146	nitrite reductase [NAD(P)H] activity
BB936_01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BB936_01910	COG0402	S-adenosylhomocysteine deaminase activity
BB936_01915	COG0738	Major facilitator superfamily
BB936_01925	COG1486	melibiose metabolic process
BB936_01930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BB936_01935	COG0433	COG0433 Predicted ATPase
BB936_01960	COG1765	OsmC-like protein
BB936_01965	COG3954	Phosphoribulokinase
BB936_01970	COG3089	Belongs to the UPF0270 family
BB936_01975	COG0429	hydrolase of the alpha beta-hydrolase fold
BB936_01990	COG4521	taurine ABC transporter
BB936_02000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB936_02005	COG2175	clavaminate synthase activity
BB936_02020	COG0488	(ABC) transporter
BB936_02025	COG2249	NAD(P)H dehydrogenase (quinone) activity
BB936_02035	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BB936_02040	COG1047	Peptidyl-prolyl cis-trans
BB936_02045	COG2900	Belongs to the SlyX family
BB936_02050	COG0545	Peptidyl-prolyl cis-trans isomerase
BB936_02055	COG2964	Protein conserved in bacteria
BB936_02060	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BB936_02065	COG2923	Belongs to the DsrF TusC family
BB936_02070	COG2168	tRNA wobble position uridine thiolation
BB936_02075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BB936_02080	COG0049	tRNA binding
BB936_02105	COG0051	transcription antitermination factor activity, RNA binding
BB936_02110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BB936_02115	COG0088	Forms part of the polypeptide exit tunnel
BB936_02120	COG0089	rRNA binding
BB936_02125	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BB936_02130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BB936_02135	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BB936_02140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BB936_02145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BB936_02150	COG0255	Belongs to the universal ribosomal protein uL29 family
BB936_02155	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BB936_02160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BB936_02165	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BB936_02170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BB936_02175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BB936_02185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BB936_02190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BB936_02195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BB936_02200	COG1841	ribosomal large subunit assembly
BB936_02205	COG0200	Binds to the 23S rRNA
BB936_02210	COG0201	protein transport
BB936_02215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BB936_02225	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BB936_02230	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BB936_02235	COG0202	RNA polymerase activity
BB936_02240	COG0203	ribosomal protein L17
BB936_02250	COG0789	Transcriptional regulator
BB936_02255	COG3036	rescue of stalled ribosome
BB936_02265	COG1970	mechanosensitive ion channel activity
BB936_02270	COG0569	domain protein
BB936_02275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB936_02275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BB936_02280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB936_02285	COG0242	peptide deformylase activity
BB936_02290	COG0758	DNA mediated transformation
BB936_02300	COG0551	DNA topoisomerase type I activity
BB936_02305	COG0009	L-threonylcarbamoyladenylate synthase
BB936_02310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BB936_02315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BB936_02350	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BB936_02355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BB936_02360	COG2224	Isocitrate lyase
BB936_02365	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BB936_02370	COG1414	Transcriptional regulator
BB936_02395	COG0527	aspartate kinase activity
BB936_02400	COG0166	Belongs to the GPI family
BB936_02415	COG3833	ABC-type maltose transport systems, permease component
BB936_02420	COG1175	transmembrane transport
BB936_02425	COG2182	Extracellular solute-binding protein
BB936_02435	COG4580	involved in the transport of maltose and maltodextrins
BB936_02450	COG3161	chorismate lyase activity
BB936_02455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BB936_02460	COG2937	Belongs to the GPAT DAPAT family
BB936_02465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BB936_02470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BB936_02475	COG3237	CsbD-like
BB936_02480	COG0735	belongs to the Fur family
BB936_02485	COG2755	lipolytic protein G-D-S-L family
BB936_02485	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BB936_02490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BB936_02510	COG0305	Participates in initiation and elongation during chromosome replication
BB936_02515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB936_02520	COG1448	Aminotransferase
BB936_02525	COG2315	Protein conserved in bacteria
BB936_02530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB936_02540	COG3550	peptidyl-serine autophosphorylation
BB936_02555	COG2252	PERMEase
BB936_02560	COG0025	NhaP-type Na H and K H
BB936_02565	COG0583	DNA-binding transcription factor activity
BB936_02570	COG1380	Effector of murein hydrolase LrgA
BB936_02580	COG1126	abc transporter atp-binding protein
BB936_02585	COG0765	amino acid transport
BB936_02590	COG4597	amino acid ABC transporter
BB936_02595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB936_02610	COG1560	Kdo2-lipid A biosynthetic process
BB936_02615	COG0471	metal ion transport
BB936_02620	COG1278	Cold shock
BB936_02625	COG1278	Cold shock
BB936_02630	COG3133	Outer membrane lipoprotein
BB936_02640	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BB936_02645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BB936_02650	COG2264	protein methyltransferase activity
BB936_02655	COG4145	pantothenate transmembrane transporter activity
BB936_02660	COG3924	membrane
BB936_02665	COG0439	Biotin carboxylase
BB936_02670	COG0511	ligase activity, forming carbon-carbon bonds
BB936_02675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BB936_02680	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BB936_02690	COG0604	alcohol dehydrogenase
BB936_02695	COG2199	diguanylate cyclase activity
BB936_02695	COG2200	EAL domain
BB936_02700	COG1077	Cell shape determining protein MreB Mrl
BB936_02705	COG1792	Involved in formation and maintenance of cell shape
BB936_02710	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BB936_02720	COG1530	ribonuclease E activity
BB936_02725	COG3164	Protein of unknown function
BB936_02730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB936_02735	COG0312	modulator of DNA gyrase
BB936_02805	COG0583	DNA-binding transcription factor activity
BB936_02815	COG1566	PFAM secretion protein HlyD family protein
BB936_02820	COG1289	transmembrane transporter activity
BB936_02835	COG2732	(Barnase) inhibitor
BB936_02840	COG3028	Belongs to the UPF0307 family
BB936_02845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BB936_03020	COG0312	modulator of DNA gyrase
BB936_03030	COG3783	Cytochrome b(562)
BB936_03035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB936_03065	COG3964	amidohydrolase
BB936_03085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_03085	COG3711	transcriptional antiterminator
BB936_03090	COG3093	addiction module antidote protein HigA
BB936_03115	COG0366	Alpha amylase catalytic
BB936_03135	COG2308	Evidence 4 Homologs of previously reported genes of
BB936_03145	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BB936_03150	COG0540	Belongs to the ATCase OTCase family
BB936_03155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_03160	COG1660	Displays ATPase and GTPase activities
BB936_03165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_03175	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BB936_03180	COG1137	ATPase activity
BB936_03185	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BB936_03190	COG3117	lipopolysaccharide transmembrane transporter activity
BB936_03195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BB936_03200	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BB936_03200	COG0517	IMP dehydrogenase activity
BB936_03210	COG1127	ABC transporter
BB936_03215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BB936_03220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BB936_03225	COG2854	intermembrane phospholipid transfer
BB936_03230	COG3113	response to antibiotic
BB936_03235	COG5007	Belongs to the BolA IbaG family
BB936_03240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB936_03245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB936_03250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB936_03255	COG3105	Protein conserved in bacteria
BB936_03260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BB936_03265	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BB936_03270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BB936_03275	COG0625	glutathione transferase activity
BB936_03280	COG2969	positive regulation of protein catabolic process
BB936_03295	COG0493	'glutamate synthase
BB936_03300	COG0070	glutamate synthase
BB936_03300	COG0067	glutamate synthase
BB936_03300	COG0069	glutamate synthase activity
BB936_03310	COG0784	Response regulator, receiver
BB936_03310	COG5002	protein histidine kinase activity
BB936_03310	COG2198	Histidine kinase
BB936_03315	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BB936_03320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB936_03325	COG2823	Periplasmic or secreted lipoprotein
BB936_03330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BB936_03335	COG0792	nuclease activity
BB936_03345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BB936_03400	COG3121	Chaperone
BB936_03420	COG0667	Aldo Keto reductase
BB936_03425	COG1064	alcohol dehydrogenase
BB936_03430	COG1741	Belongs to the pirin family
BB936_03435	COG0583	DNA-binding transcription factor activity
BB936_03440	COG0435	Glutathione S-transferase
BB936_03445	COG2259	Doxx family
BB936_03455	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BB936_03460	COG4575	ribosome binding
BB936_03475	COG0586	Pfam SNARE associated Golgi protein
BB936_03490	COG2271	Major facilitator Superfamily
BB936_03495	COG1904	glucuronate isomerase
BB936_03500	COG0246	Mannitol dehydrogenase
BB936_03505	COG2721	sulfolactate sulfo-lyase activity
BB936_03515	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BB936_03520	COG0861	Integral membrane protein TerC family
BB936_03530	COG0673	inositol 2-dehydrogenase activity
BB936_03535	COG1451	nucleotide metabolic process
BB936_03560	COG2813	Specifically methylates the guanine in position
BB936_03565	COG1902	pentaerythritol trinitrate reductase activity
BB936_03565	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB936_03575	COG3247	response to pH
BB936_03585	COG0076	glutamate decarboxylase activity
BB936_03605	COG3328	transposase activity
BB936_03610	COG1263	PTS System
BB936_03610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_03615	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BB936_03625	COG1472	Belongs to the glycosyl hydrolase 3 family
BB936_03635	COG3876	Protein conserved in bacteria
BB936_03650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB936_03655	COG0358	DNA primase activity
BB936_03665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BB936_03670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BB936_03675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BB936_03680	COG1968	undecaprenyl-diphosphatase activity
BB936_03685	COG0617	tRNA 3'-terminal CCA addition
BB936_03690	COG4991	sh3 domain protein
BB936_03695	COG3025	triphosphatase activity
BB936_03700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BB936_03705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BB936_03705	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BB936_03710	COG0531	amino acid
BB936_03720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BB936_03725	COG3384	dioxygenase
BB936_03730	COG0754	glutathionylspermidine amidase activity
BB936_03735	COG5463	Belongs to the UPF0441 family
BB936_03745	COG1538	Outer membrane efflux protein
BB936_03750	COG0494	nUDIX hydrolase
BB936_03755	COG3151	Protein conserved in bacteria
BB936_03760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BB936_03765	COG3150	esterase
BB936_03770	COG0187	DNA topoisomerase II activity
BB936_03780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BB936_03785	COG2249	NAD(P)H dehydrogenase (quinone) activity
BB936_03790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BB936_03795	COG0204	Acyl-transferase
BB936_03800	COG2132	Multicopper oxidase
BB936_03810	COG0656	L-ascorbic acid biosynthetic process
BB936_03815	COG1979	alcohol dehydrogenase
BB936_03820	COG2207	Transcriptional regulator
BB936_03825	COG0586	Pfam SNARE associated Golgi protein
BB936_03830	COG0626	cystathionine gamma-synthase activity
BB936_03835	COG0811	peptide transport
BB936_03840	COG0848	biopolymer transport protein
BB936_03890	COG4964	Belongs to the GSP D family
BB936_03915	COG3145	DNA-N1-methyladenine dioxygenase activity
BB936_03920	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB936_03930	COG2135	peptidase activity
BB936_03950	COG2963	transposase activity
BB936_03970	COG1136	(ABC) transporter
BB936_03970	COG0577	efflux transmembrane transporter activity
BB936_03985	COG2801	Transposase and inactivated derivatives
BB936_04015	COG1815	bacterial-type flagellum-dependent cell motility
BB936_04020	COG1558	bacterial-type flagellum-dependent cell motility
BB936_04025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BB936_04030	COG1749	Flagellar hook protein flgE
BB936_04040	COG4786	Flagellar basal body rod
BB936_04050	COG1706	bacterial-type flagellum-dependent cell motility
BB936_04085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BB936_04090	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BB936_04095	COG1516	flagellar protein fliS
BB936_04115	COG1191	sigma factor activity
BB936_04120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BB936_04130	COG3133	Outer membrane lipoprotein
BB936_04135	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BB936_04140	COG0437	4 iron, 4 sulfur cluster binding
BB936_04145	COG5557	Pfam Polysulphide reductase, NrfD
BB936_04150	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BB936_04155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BB936_04160	COG1773	rubredoxin
BB936_04165	COG0375	protein maturation
BB936_04170	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BB936_04175	COG0298	carbon dioxide binding
BB936_04180	COG0409	Hydrogenase expression formation protein
BB936_04185	COG0309	Hydrogenase expression formation protein (HypE)
BB936_04190	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BB936_04200	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BB936_04215	COG5001	Diguanylate cyclase
BB936_04220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB936_04235	COG0477	Major facilitator Superfamily
BB936_04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
BB936_04260	COG1609	Transcriptional regulator
BB936_04270	COG0477	Major facilitator Superfamily
BB936_04280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB936_04285	COG0697	spore germination
BB936_04300	COG4607	ABC-type enterochelin transport system periplasmic component
BB936_04310	COG4605	iron ion homeostasis
BB936_04320	COG0024	Methionine aminopeptidase
BB936_04345	COG1289	transmembrane transporter activity
BB936_04355	COG1982	Orn Lys Arg decarboxylase major
BB936_04360	COG0531	amino acid
BB936_04405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BB936_04420	COG1982	Orn Lys Arg decarboxylase major
BB936_04430	COG0741	lytic transglycosylase activity
BB936_04435	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BB936_04440	COG1194	a g-specific adenine glycosylase
BB936_04445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BB936_04450	COG3171	Protein conserved in bacteria
BB936_04455	COG2066	Belongs to the glutaminase family
BB936_04465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB936_04470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BB936_04475	COG1872	DUF167
BB936_04480	COG0762	integral membrane protein
BB936_04485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BB936_04490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BB936_04495	COG2805	Type II/IV secretion system protein
BB936_04505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB936_04510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BB936_04515	COG1678	Uncharacterized ACR, COG1678
BB936_04520	COG0189	ligase activity
BB936_04525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BB936_04530	COG2356	endonuclease I
BB936_04535	COG3091	SprT-like family
BB936_04540	COG0640	Transcriptional regulator
BB936_04555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BB936_04560	COG1166	arginine decarboxylase activity
BB936_04570	COG0501	Belongs to the peptidase M48B family
BB936_04575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BB936_04580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BB936_04585	COG0126	phosphoglycerate kinase activity
BB936_04590	COG0191	fructose-bisphosphate aldolase activity
BB936_04610	COG1279	arginine transmembrane transporter activity
BB936_04620	COG0583	DNA-binding transcription factor activity
BB936_04625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BB936_04630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB936_04665	COG0602	queuosine metabolic process
BB936_04685	COG0720	synthase
BB936_04690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BB936_04695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BB936_04700	COG0175	sulfate reduction
BB936_04715	COG2234	aminopeptidase activity
BB936_04720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BB936_04720	COG1648	precorrin-2 dehydrogenase activity
BB936_04725	COG0175	sulfate reduction
BB936_04730	COG2895	sulfate adenylyltransferase (ATP) activity
BB936_04735	COG0529	Catalyzes the synthesis of activated sulfate
BB936_04745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BB936_04755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BB936_04760	COG0585	pseudouridine synthase activity
BB936_04765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BB936_04770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BB936_04775	COG1388	LysM domain
BB936_04775	COG4942	peptidase
BB936_04780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB936_04785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BB936_04810	COG3188	usher protein
BB936_04815	COG3121	Chaperone
BB936_04825	COG3539	Fimbrial protein
BB936_04830	COG3539	Fimbrial protein
BB936_04860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB936_04870	COG1538	Outer membrane efflux protein
BB936_04890	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_04900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB936_04905	COG1858	cytochrome C peroxidase
BB936_04920	COG0640	Transcriptional regulator
BB936_04975	COG0410	ABC transporter
BB936_04980	COG1137	ATPase activity
BB936_04985	COG4177	L-phenylalanine transmembrane transporter activity
BB936_04990	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB936_05000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BB936_05000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BB936_05005	COG0243	molybdopterin cofactor binding
BB936_05010	COG0437	4 iron, 4 sulfur cluster binding
BB936_05015	COG3302	dmso reductase anchor subunit
BB936_05020	COG3381	protein complex oligomerization
BB936_05040	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BB936_05045	COG2137	regulation of response to DNA damage stimulus
BB936_05050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BB936_05055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BB936_05075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB936_05085	COG2918	glutathione biosynthetic process
BB936_05090	COG1854	S-ribosylhomocysteine lyase activity
BB936_05100	COG4137	Cytochrome C assembly protein
BB936_05105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BB936_05110	COG0228	four-way junction DNA binding
BB936_05115	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BB936_05120	COG0336	Belongs to the RNA methyltransferase TrmD family
BB936_05125	COG0335	large ribosomal subunit rRNA binding
BB936_05140	COG3279	Response regulator of the LytR AlgR family
BB936_05145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB936_05150	COG1605	Chorismate mutase
BB936_05150	COG0287	Prephenate dehydrogenase
BB936_05155	COG0077	Prephenate dehydratase
BB936_05155	COG1605	Chorismate mutase
BB936_05165	COG0542	response to heat
BB936_05175	COG0564	pseudouridine synthase activity
BB936_05180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB936_05195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BB936_05200	COG3328	transposase activity
BB936_05230	COG5544	Lipoprotein
BB936_05235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB936_05240	COG1042	CoA-binding domain protein
BB936_05240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB936_05240	COG0045	succinate-CoA ligase (ADP-forming) activity
BB936_05250	COG3118	belongs to the thioredoxin family
BB936_05255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB936_05270	COG2814	Major facilitator Superfamily
BB936_05275	COG1566	PFAM secretion protein HlyD family protein
BB936_05280	COG1538	Outer membrane efflux protein
BB936_05285	COG1846	Transcriptional regulator
BB936_05295	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BB936_05300	COG2814	Major facilitator Superfamily
BB936_05335	COG0765	amino acid transport
BB936_05340	COG0765	amino acid transport
BB936_05365	COG0436	Aminotransferase
BB936_05370	COG0582	viral genome integration into host DNA
BB936_05485	COG1484	DNA-dependent DNA replication
BB936_05640	COG4386	tail sheath protein
BB936_05700	COG0235	Class ii aldolase
BB936_05705	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BB936_05710	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BB936_05715	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BB936_05720	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BB936_05740	COG1960	acyl-CoA dehydrogenase activity
BB936_05750	COG0121	glutamine amidotransferase
BB936_05755	COG3034	peptidoglycan biosynthetic process
BB936_05760	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BB936_05765	COG1805	sodium ion transport
BB936_05770	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BB936_05775	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BB936_05780	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BB936_05785	COG2871	sodium ion transport
BB936_05790	COG1477	protein flavinylation
BB936_05795	COG2991	Protein conserved in bacteria
BB936_05805	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB936_05810	COG2964	Protein conserved in bacteria
BB936_05825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BB936_05830	COG2195	Cleaves the N-terminal amino acid of tripeptides
BB936_05835	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BB936_05855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BB936_05860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BB936_05865	COG2188	Transcriptional regulator
BB936_05885	COG3459	Glycosyltransferase 36 associated
BB936_05900	COG2226	methyltransferase
BB936_05925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BB936_05930	COG3123	guanosine phosphorylase activity
BB936_05935	COG2974	May be involved in recombination
BB936_05940	COG1940	carbohydrate kinase activity
BB936_05945	COG0419	ATPase involved in DNA repair
BB936_05950	COG0420	3'-5' exonuclease activity
BB936_05955	COG0745	RESPONSE REGULATOR receiver
BB936_05960	COG5002	protein histidine kinase activity
BB936_05970	COG1114	Component of the transport system for branched-chain amino acids
BB936_05980	COG0366	Alpha amylase catalytic
BB936_06000	COG0450	alkyl hydroperoxide reductase
BB936_06005	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BB936_06010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BB936_06025	COG0343	queuine tRNA-ribosyltransferase activity
BB936_06030	COG1862	Preprotein translocase
BB936_06035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB936_06040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB936_06055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BB936_06060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BB936_06060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BB936_06065	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BB936_06070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB936_06075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BB936_06080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BB936_06090	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BB936_06095	COG0142	geranyltranstransferase activity
BB936_06105	COG0301	tRNA thio-modification
BB936_06105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BB936_06110	COG0693	protein deglycase activity
BB936_06115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BB936_06120	COG1666	GTP binding
BB936_06125	COG2814	Major facilitator Superfamily
BB936_06130	COG0109	protoheme IX farnesyltransferase activity
BB936_06135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BB936_06140	COG1845	cytochrome c oxidase, subunit III
BB936_06145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB936_06150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BB936_06160	COG2223	nitrite transmembrane transporter activity
BB936_06165	COG3056	Lipoprotein
BB936_06170	COG0271	Belongs to the BolA IbaG family
BB936_06180	COG0544	peptidyl-prolyl cis-trans isomerase activity
BB936_06185	COG0740	serine-type endopeptidase activity
BB936_06190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BB936_06195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BB936_06200	COG0776	regulation of translation
BB936_06205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB936_06210	COG1555	photosystem II stabilization
BB936_06215	COG0824	Thioesterase
BB936_06220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BB936_06230	COG0561	phosphatase activity
BB936_06240	COG1522	sequence-specific DNA binding
BB936_06245	COG1132	(ABC) transporter
BB936_06250	COG1132	(ABC) transporter
BB936_06255	COG0347	Belongs to the P(II) protein family
BB936_06260	COG0004	ammonium transporteR
BB936_06265	COG1946	Acyl-CoA thioesterase
BB936_06270	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BB936_06275	COG3695	enzyme binding
BB936_06305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB936_06310	COG0803	Belongs to the bacterial solute-binding protein 9 family
BB936_06315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BB936_06320	COG0254	rRNA binding
BB936_06335	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BB936_06340	COG3457	Alanine racemase
BB936_06350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB936_06355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB936_06360	COG1309	transcriptional regulator
BB936_06365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BB936_06385	COG2832	Protein of unknown function (DUF454)
BB936_06390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BB936_06400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BB936_06405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BB936_06410	COG0326	Molecular chaperone. Has ATPase activity
BB936_06415	COG0563	adenylate kinase activity
BB936_06420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BB936_06430	COG1216	Glycosyl transferase, family 2
BB936_06430	COG1442	glycosyl transferase family 8
BB936_06435	COG1215	transferase activity, transferring glycosyl groups
BB936_06440	COG0438	transferase activity, transferring glycosyl groups
BB936_06445	COG0438	transferase activity, transferring glycosyl groups
BB936_06450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB936_06470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB936_06475	COG4651	solute:proton antiporter activity
BB936_06475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BB936_06480	COG2223	nitrite transmembrane transporter activity
BB936_06495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BB936_06500	COG3735	TraB family
BB936_06505	COG2217	Heavy metal translocating P-type atpase
BB936_06510	COG0789	Transcriptional regulator
BB936_06515	COG1585	Membrane protein implicated in regulation of membrane protease activity
BB936_06520	COG0330	HflC and HflK could
BB936_06525	COG3118	belongs to the thioredoxin family
BB936_06530	COG0300	oxidoreductase activity
BB936_06535	COG2755	lipolytic protein G-D-S-L family
BB936_06540	COG4181	ATPase activity
BB936_06545	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BB936_06550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BB936_06555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BB936_06560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BB936_06565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BB936_06570	COG0215	cysteine-tRNA ligase activity
BB936_06575	COG2501	S4 domain
BB936_06580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BB936_06640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB936_06725	COG0305	Participates in initiation and elongation during chromosome replication
BB936_06775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB936_06845	COG0494	nUDIX hydrolase
BB936_06955	COG0582	viral genome integration into host DNA
BB936_06960	COG0582	viral genome integration into host DNA
BB936_06975	COG3177	Filamentation induced by cAMP protein fic
BB936_07055	COG2850	peptidyl-arginine hydroxylation
BB936_07070	COG5265	(ABC) transporter
BB936_07085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB936_07100	COG1278	Cold shock
BB936_07105	COG1278	Cold shock
BB936_07110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BB936_07115	COG3706	GGDEF domain
BB936_07120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB936_07125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BB936_07130	COG0321	lipoyl(octanoyl) transferase activity
BB936_07135	COG2921	Belongs to the UPF0250 family
BB936_07140	COG1686	Belongs to the peptidase S11 family
BB936_07145	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BB936_07150	COG0772	Belongs to the SEDS family
BB936_07155	COG0768	penicillin binding
BB936_07165	COG0799	negative regulation of ribosome biogenesis
BB936_07170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BB936_07175	COG1466	dna polymerase III delta subunit
BB936_07180	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BB936_07185	COG0495	leucyl-tRNA aminoacylation
BB936_07190	COG2888	peptidyl-tyrosine sulfation
BB936_07195	COG1126	abc transporter atp-binding protein
BB936_07200	COG0765	amino acid transport
BB936_07205	COG0765	amino acid transport
BB936_07220	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BB936_07225	COG4535	Mg2 and Co2 transporter CorC
BB936_07235	COG1702	phosphate starvation-inducible protein PhoH
BB936_07240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BB936_07245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB936_07280	COG0367	asparagine synthase
BB936_07285	COG0647	UMP catabolic process
BB936_07290	COG1940	carbohydrate kinase activity
BB936_07290	COG1846	Transcriptional regulator
BB936_07295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BB936_07300	COG0363	glucosamine-6-phosphate deaminase activity
BB936_07305	COG1263	PTS System
BB936_07305	COG2190	(PTS) system
BB936_07305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_07310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB936_07330	COG0735	belongs to the Fur family
BB936_07340	COG0840	transmembrane signaling receptor activity
BB936_07350	COG0596	Alpha beta hydrolase
BB936_07355	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BB936_07360	COG0033	Phosphoglucomutase
BB936_07375	COG0745	RESPONSE REGULATOR receiver
BB936_07380	COG2205	protein histidine kinase activity
BB936_07385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BB936_07390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BB936_07395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BB936_07415	COG2994	toxin metabolic process
BB936_07425	COG3272	Protein of unknown function (DUF1722)
BB936_07435	COG5212	phosphodiesterase
BB936_07440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BB936_07445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BB936_07450	COG1984	allophanate hydrolase subunit 2
BB936_07455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BB936_07470	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BB936_07480	COG2009	succinate dehydrogenase
BB936_07485	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BB936_07490	COG1053	succinate dehydrogenase
BB936_07500	COG0567	Dehydrogenase, E1 component
BB936_07505	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB936_07510	COG0045	succinate-CoA ligase (ADP-forming) activity
BB936_07515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BB936_07520	COG0737	Belongs to the 5'-nucleotidase family
BB936_07525	COG1271	oxidase subunit
BB936_07530	COG1294	oxidase, subunit
BB936_07535	COG4890	Cyd operon protein YbgT
BB936_07540	COG3790	cyd operon protein YbgE
BB936_07545	COG0824	Thioesterase
BB936_07550	COG0811	peptide transport
BB936_07555	COG0848	biopolymer transport protein
BB936_07560	COG3064	Membrane
BB936_07560	COG3064	Membrane
BB936_07565	COG0823	Involved in the tonB-independent uptake of proteins
BB936_07570	COG2885	chlorophyll binding
BB936_07575	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BB936_07595	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BB936_07605	COG1230	cation diffusion facilitator family transporter
BB936_07610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB936_07615	COG0588	phosphoglycerate mutase activity
BB936_07640	COG2017	converts alpha-aldose to the beta-anomer
BB936_07645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BB936_07650	COG1085	galactose-1-phosphate uridylyltransferase
BB936_07655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BB936_07665	COG1119	ATPase activity
BB936_07670	COG2005	Transcriptional regulator
BB936_07670	COG3585	molybdate ion transport
BB936_07680	COG0725	ABC transporter, periplasmic molybdate-binding protein
BB936_07685	COG0582	viral genome integration into host DNA
BB936_07805	COG1484	DNA-dependent DNA replication
BB936_07810	COG0305	Participates in initiation and elongation during chromosome replication
BB936_07825	COG3772	lysozyme
BB936_07985	COG4149	molybdate abc transporter
BB936_07995	COG0561	phosphatase activity
BB936_08000	COG2706	6-phosphogluconolactonase activity
BB936_08010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BB936_08015	COG0156	8-amino-7-oxononanoate synthase activity
BB936_08020	COG2226	methyltransferase
BB936_08025	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BB936_08035	COG0556	nucleotide-excision repair
BB936_08040	COG4628	conserved protein (DUF2132)
BB936_08045	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BB936_08050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BB936_08055	COG0315	cyclic pyranopterin monophosphate synthase activity
BB936_08060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BB936_08065	COG0314	molybdopterin synthase activity
BB936_08070	COG0670	Belongs to the BI1 family
BB936_08075	COG0842	Transport permease protein
BB936_08080	COG0842	Transport permease protein
BB936_08085	COG1131	(ABC) transporter
BB936_08090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB936_08095	COG1309	transcriptional regulator
BB936_08100	COG0513	Belongs to the DEAD box helicase family
BB936_08105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BB936_08115	COG2239	Acts as a magnesium transporter
BB936_08120	COG1686	Belongs to the peptidase S11 family
BB936_08125	COG0277	FAD linked oxidase domain protein
BB936_08135	COG1403	HNH endonuclease
BB936_08145	COG2261	transglycosylase associated protein
BB936_08155	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BB936_08170	COG4807	Protein conserved in bacteria
BB936_08190	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BB936_08200	COG2897	thiosulfate sulfurtransferase activity
BB936_08215	COG1732	Glycine betaine
BB936_08220	COG1174	glycine betaine transport
BB936_08225	COG1125	glycine betaine transport
BB936_08230	COG1174	glycine betaine transport
BB936_08245	COG0583	DNA-binding transcription factor activity
BB936_08255	COG0697	spore germination
BB936_08275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB936_08280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BB936_08300	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BB936_08315	COG1126	abc transporter atp-binding protein
BB936_08325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB936_08330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BB936_08335	COG0783	Belongs to the Dps family
BB936_08340	COG4106	trans-aconitate 2-methyltransferase activity
BB936_08355	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BB936_08375	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BB936_08395	COG0488	(ABC) transporter
BB936_08405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BB936_08410	COG0303	'Molybdopterin
BB936_08425	COG1136	(ABC) transporter
BB936_08425	COG0577	efflux transmembrane transporter activity
BB936_08455	COG0583	DNA-binding transcription factor activity
BB936_08460	COG0477	Major facilitator Superfamily
BB936_08465	COG0302	gtp cyclohydrolase
BB936_08470	COG2311	Membrane
BB936_08495	COG3604	Transcriptional regulator
BB936_08505	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BB936_08510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BB936_08520	COG3260	NADH ubiquinone oxidoreductase 20
BB936_08525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB936_08530	COG3261	NADH dehydrogenase
BB936_08530	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BB936_08535	COG0651	ATP synthesis coupled electron transport
BB936_08540	COG4237	Hydrogenase 4 membrane
BB936_08545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BB936_08550	COG0650	Formate hydrogenlyase subunit 4
BB936_08555	COG0651	ATP synthesis coupled electron transport
BB936_08560	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BB936_08565	COG0375	protein maturation
BB936_08570	COG0298	carbon dioxide binding
BB936_08575	COG2949	membrane
BB936_08580	COG0281	malic enzyme
BB936_08595	COG1346	cytolysis
BB936_08600	COG1380	Effector of murein hydrolase LrgA
BB936_08605	COG2814	Major facilitator Superfamily
BB936_08625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB936_08625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB936_08630	COG0489	protein tyrosine kinase activity
BB936_08635	COG0572	uridine kinase
BB936_08645	COG2982	Protein involved in outer membrane biogenesis
BB936_08650	COG3069	C4-dicarboxylate transmembrane transporter activity
BB936_08655	COG1253	flavin adenine dinucleotide binding
BB936_08700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB936_08720	COG3328	transposase activity
BB936_08745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BB936_08750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BB936_08760	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BB936_08765	COG0140	phosphoribosyl-ATP diphosphatase activity
BB936_08765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BB936_08770	COG0107	imidazoleglycerol-phosphate synthase activity
BB936_08775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BB936_08780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BB936_08785	COG0131	Imidazoleglycerol-phosphate dehydratase
BB936_08785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BB936_08790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB936_08800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BB936_08805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB936_08815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB936_08820	COG1129	ABC transporter
BB936_08825	COG0371	Dehydrogenase
BB936_08835	COG0531	amino acid
BB936_08840	COG2925	Exonuclease
BB936_08845	COG1022	Amp-dependent synthetase and ligase
BB936_08845	COG3320	Male sterility
BB936_08850	COG1289	transmembrane transporter activity
BB936_08855	COG2926	Belongs to the UPF0265 family
BB936_08865	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB936_08875	COG1879	ABC-type sugar transport system periplasmic component
BB936_08885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB936_08895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BB936_08905	COG4810	utilization protein
BB936_08925	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BB936_08960	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BB936_08990	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BB936_08995	COG2241	protein methyltransferase activity
BB936_09005	COG2875	Belongs to the precorrin methyltransferase family
BB936_09055	COG1492	cobalamin metabolic process
BB936_09075	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BB936_09145	COG3121	Chaperone
BB936_09195	COG3501	Rhs element vgr protein
BB936_09220	COG0137	argininosuccinate synthase activity
BB936_09225	COG0534	Mate efflux family protein
BB936_09235	COG0352	thiamine-phosphate diphosphorylase activity
BB936_09240	COG0561	phosphatase activity
BB936_09245	COG1349	DNA-binding transcription factor activity
BB936_09255	COG0784	Response regulator, receiver
BB936_09255	COG0835	chemotaxis
BB936_09285	COG3842	ATPase activity
BB936_09295	COG1840	ABC-type Fe3 transport system, periplasmic component
BB936_09300	COG2271	Major facilitator Superfamily
BB936_09315	COG4565	transcriptional regulatory protein
BB936_09320	COG3290	protein histidine kinase activity
BB936_09335	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BB936_09340	COG3052	prosthetic group binding
BB936_09345	COG2301	Belongs to the HpcH HpaI aldolase family
BB936_09350	COG3051	citrate lyase alpha subunit
BB936_09355	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
BB936_09355	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BB936_09365	COG0471	metal ion transport
BB936_09380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB936_09400	COG2814	Major facilitator Superfamily
BB936_09405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_09405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_09410	COG3122	Protein conserved in bacteria
BB936_09430	COG3121	Chaperone
BB936_09470	COG3228	Belongs to the MtfA family
BB936_09480	COG1070	Carbohydrate kinase
BB936_09505	COG3121	Chaperone
BB936_09515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BB936_09545	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_09545	COG0604	alcohol dehydrogenase
BB936_09545	COG3321	synthase
BB936_09550	COG3328	transposase activity
BB936_09555	COG3250	beta-galactosidase activity
BB936_09560	COG1609	Transcriptional regulator
BB936_09565	COG1278	Cold shock
BB936_09575	COG0840	transmembrane signaling receptor activity
BB936_09590	COG1285	pathogenesis
BB936_09600	COG2130	NADP-dependent
BB936_09605	COG0589	response to stress
BB936_09625	COG1360	Flagellar Motor Protein
BB936_09630	COG0643	Histidine kinase
BB936_09630	COG2198	Histidine kinase
BB936_09635	COG0835	chemotaxis
BB936_09640	COG0840	transmembrane signaling receptor activity
BB936_09645	COG0840	transmembrane signaling receptor activity
BB936_09650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BB936_09660	COG0745	RESPONSE REGULATOR receiver
BB936_09665	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BB936_09675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BB936_09680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BB936_09695	COG3418	PFAM FlgN family protein
BB936_09700	COG2747	anti-sigma28 factor FlgM
BB936_09710	COG1815	bacterial-type flagellum-dependent cell motility
BB936_09715	COG1558	bacterial-type flagellum-dependent cell motility
BB936_09720	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BB936_09725	COG1749	Flagellar hook protein flgE
BB936_09735	COG4786	Flagellar basal body rod
BB936_09755	COG1256	bacterial-type flagellum assembly
BB936_09760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BB936_09775	COG1338	Plays a role in the flagellum-specific transport system
BB936_09795	COG1580	Controls the rotational direction of flagella during chemotaxis
BB936_09805	COG2882	bacterial-type flagellum organization
BB936_09815	COG1317	bacterial-type flagellum organization
BB936_09820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BB936_09830	COG1677	Flagellar hook-basal body complex protein FliE
BB936_09835	COG0582	viral genome integration into host DNA
BB936_09855	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BB936_09860	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BB936_09900	COG1191	sigma factor activity
BB936_09910	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BB936_09940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BB936_09940	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BB936_09940	COG0506	proline dehydrogenase activity
BB936_09960	COG3157	Type VI secretion system effector, Hcp
BB936_09985	COG0655	NAD(P)H dehydrogenase (quinone) activity
BB936_09995	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
BB936_10010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BB936_10015	COG0778	Nitroreductase
BB936_10020	COG2267	carboxylic ester hydrolase activity
BB936_10025	COG0251	oxidation-reduction process
BB936_10030	COG1335	isochorismatase
BB936_10040	COG1309	transcriptional regulator
BB936_10045	COG1113	amino acid transport
BB936_10055	COG0582	viral genome integration into host DNA
BB936_10060	COG2963	transposase activity
BB936_10085	COG0366	Alpha amylase catalytic
BB936_10095	COG3136	membrane protein required for alginate biosynthesis
BB936_10105	COG2197	response regulator
BB936_10110	COG0322	excinuclease ABC activity
BB936_10115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BB936_10265	COG4695	Portal protein
BB936_10300	COG5002	protein histidine kinase activity
BB936_10300	COG2176	DNA-directed DNA polymerase activity
BB936_10350	COG4974	Belongs to the 'phage' integrase family
BB936_10470	COG3772	lysozyme
BB936_10475	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BB936_10480	COG2979	Protein of unknown function (DUF533)
BB936_10495	COG0012	GTP binding
BB936_10505	COG0193	aminoacyl-tRNA hydrolase activity
BB936_10520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BB936_10530	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BB936_10535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BB936_10540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BB936_10545	COG2890	protein-(glutamine-N5) methyltransferase activity
BB936_10550	COG3094	Invasion gene expression up-regulator, SirB
BB936_10555	COG2912	Transglutaminase-like superfamily
BB936_10560	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BB936_10565	COG0659	secondary active sulfate transmembrane transporter activity
BB936_10570	COG3706	GGDEF domain
BB936_10595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BB936_10600	COG3381	protein complex oligomerization
BB936_10610	COG0477	Major facilitator Superfamily
BB936_10625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB936_10635	COG0673	inositol 2-dehydrogenase activity
BB936_10640	COG0728	peptidoglycan biosynthetic process
BB936_10645	COG0387	Pfam Sodium calcium exchanger
BB936_10655	COG2814	Major facilitator Superfamily
BB936_10665	COG1335	isochorismatase
BB936_10670	COG0252	asparaginase activity
BB936_10675	COG0616	signal peptide processing
BB936_10680	COG0778	Nitroreductase
BB936_10690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BB936_10700	COG0494	nUDIX hydrolase
BB936_10705	COG0708	Exodeoxyribonuclease III
BB936_10710	COG0583	DNA-binding transcription factor activity
BB936_10725	COG0788	formyltetrahydrofolate deformylase activity
BB936_10730	COG3012	SEC-C Motif Domain Protein
BB936_10740	COG1752	Esterase of the alpha-beta hydrolase superfamily
BB936_10745	COG0745	RESPONSE REGULATOR receiver
BB936_10755	COG2916	Histone family protein nucleoid-structuring protein H-NS
BB936_10765	COG1435	thymidine kinase activity
BB936_10770	COG1012	belongs to the aldehyde dehydrogenase family
BB936_10770	COG1454	alcohol dehydrogenase
BB936_10775	COG2095	MarC family integral membrane protein
BB936_10795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB936_10800	COG0444	Belongs to the ABC transporter superfamily
BB936_10810	COG3099	Belongs to the UPF0263 family
BB936_10815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB936_10830	COG2350	Protein conserved in bacteria
BB936_10835	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BB936_10840	COG1607	acyl-coa hydrolase
BB936_10845	COG2917	probably involved in intracellular septation
BB936_10865	COG3047	cAMP biosynthetic process
BB936_10875	COG0159	tryptophan synthase activity
BB936_10880	COG0133	tryptophan synthase activity
BB936_10885	COG0134	indole-3-glycerol-phosphate synthase activity
BB936_10885	COG0135	phosphoribosylanthranilate isomerase activity
BB936_10895	COG0512	Glutamine amidotransferase of anthranilate synthase
BB936_10905	COG0613	PHP domain protein
BB936_10910	COG0009	L-threonylcarbamoyladenylate synthase
BB936_10915	COG1187	pseudouridine synthase activity
BB936_10925	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BB936_10930	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_10935	COG0616	signal peptide processing
BB936_10945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BB936_10965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BB936_10970	COG0671	phosphoesterase, PA-phosphatase related
BB936_10975	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BB936_10980	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BB936_10990	COG1396	sequence-specific DNA binding
BB936_10995	COG3135	benzoate transporter
BB936_11005	COG0284	orotidine-5'-phosphate decarboxylase activity
BB936_11010	COG0023	Translation Initiation Factor
BB936_11025	COG0235	Class ii aldolase
BB936_11035	COG1349	DNA-binding transcription factor activity
BB936_11045	COG2879	small protein
BB936_11050	COG1966	Carbon starvation protein
BB936_11055	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BB936_11060	COG0243	molybdopterin cofactor binding
BB936_11065	COG0582	viral genome integration into host DNA
BB936_11195	COG1484	DNA-dependent DNA replication
BB936_11240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB936_11310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BB936_11320	COG4659	FMN binding
BB936_11325	COG4658	electron transport chain
BB936_11330	COG3708	Transcriptional regulator
BB936_11330	COG2207	Transcriptional regulator
BB936_11340	COG4656	Part of a membrane complex involved in electron transport
BB936_11350	COG4657	Part of a membrane complex involved in electron transport
BB936_11370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BB936_11380	COG2160	L-arabinose isomerase activity
BB936_11410	COG0673	inositol 2-dehydrogenase activity
BB936_11415	COG0385	Bile acid
BB936_11420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BB936_11425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BB936_11430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_11430	COG1263	PTS System
BB936_11435	COG1609	Transcriptional regulator
BB936_11445	COG5339	Protein conserved in bacteria
BB936_11455	COG0114	fumarate hydratase activity
BB936_11480	COG2814	Major facilitator Superfamily
BB936_11490	COG1940	carbohydrate kinase activity
BB936_11495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BB936_11505	COG4221	oxidoreductase activity
BB936_11520	COG2271	Major facilitator Superfamily
BB936_11540	COG3023	N-Acetylmuramoyl-L-alanine amidase
BB936_11550	COG0028	Belongs to the TPP enzyme family
BB936_11555	COG0440	acetolactate synthase activity
BB936_11560	COG1011	Hydrolase
BB936_11585	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_11590	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BB936_11605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB936_11610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB936_11615	COG0589	response to stress
BB936_11620	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BB936_11625	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BB936_11640	COG0531	amino acid
BB936_11650	COG0745	RESPONSE REGULATOR receiver
BB936_11655	COG2205	protein histidine kinase activity
BB936_11660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BB936_11670	COG3591	Belongs to the peptidase S1B family
BB936_11685	COG1643	Atp-dependent helicase
BB936_11690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BB936_11695	COG3784	Protein of unknown function (DUF1318)
BB936_11705	COG2911	Protein conserved in bacteria
BB936_11710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB936_11715	COG3042	response to heat
BB936_11720	COG1285	pathogenesis
BB936_11735	COG0823	Involved in the tonB-independent uptake of proteins
BB936_11740	COG0037	tRNA processing
BB936_11745	COG0598	Magnesium transport protein CorA
BB936_11750	COG4166	transmembrane transport
BB936_11755	COG2866	Carboxypeptidase
BB936_11760	COG4948	Mandelate Racemase Muconate Lactonizing
BB936_11765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BB936_11785	COG3768	UPF0283 membrane protein
BB936_11790	COG3106	COG3106 Predicted ATPase
BB936_11800	COG1983	PspC domain protein
BB936_11810	COG1842	Phage shock protein A
BB936_11815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BB936_11830	COG4166	transmembrane transport
BB936_11835	COG4168	peptide transport system, permease
BB936_11840	COG4171	peptide transport system, permease
BB936_11850	COG4172	Belongs to the ABC transporter superfamily
BB936_11860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB936_11860	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB936_11870	COG3104	oligopeptide transport
BB936_11895	COG0625	glutathione transferase activity
BB936_11905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BB936_11910	COG0259	pyridoxamine-phosphate oxidase activity
BB936_11915	COG3895	Periplasmic Protein
BB936_11920	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BB936_11925	COG3133	Outer membrane lipoprotein
BB936_11930	COG1846	Transcriptional regulator
BB936_11940	COG1566	PFAM secretion protein HlyD family protein
BB936_11945	COG1289	transmembrane transporter activity
BB936_11950	COG4989	oxidoreductase activity
BB936_11955	COG3313	Fe-S protein
BB936_11960	COG2194	sulfuric ester hydrolase activity
BB936_11965	COG1309	transcriptional regulator
BB936_11970	COG1902	pentaerythritol trinitrate reductase activity
BB936_11975	COG0346	lactoylglutathione lyase activity
BB936_11985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB936_11990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BB936_11995	COG0791	NLP P60 protein
BB936_12000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB936_12005	COG1609	Transcriptional regulator
BB936_12010	COG0583	DNA-binding transcription factor activity
BB936_12015	COG2814	Major facilitator Superfamily
BB936_12020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BB936_12025	COG0307	riboflavin synthase, alpha
BB936_12050	COG4238	major outer membrane lipoprotein
BB936_12055	COG1376	ErfK ybiS ycfS ynhG family protein
BB936_12055	COG1388	LysM domain
BB936_12060	COG2166	iron-sulfur cluster assembly
BB936_12070	COG0719	Fe-S assembly protein
BB936_12075	COG0396	ATPase activity
BB936_12080	COG0719	Fe-S assembly protein
BB936_12085	COG0316	Belongs to the HesB IscA family
BB936_12090	COG2050	protein possibly involved in aromatic compounds catabolism
BB936_12100	COG0277	FAD linked oxidase domain protein
BB936_12100	COG0247	lactate metabolic process
BB936_12105	COG0628	permease
BB936_12115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB936_12115	COG0574	Belongs to the PEP-utilizing enzyme family
BB936_12120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BB936_12160	COG0791	NLP P60 protein
BB936_12165	COG2076	Multidrug Resistance protein
BB936_12170	COG2076	Multidrug Resistance protein
BB936_12175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BB936_12180	COG0726	polysaccharide deacetylase
BB936_12185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB936_12185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB936_12190	COG0463	Glycosyl transferase, family 2
BB936_12195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BB936_12200	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BB936_12205	COG0386	Belongs to the glutathione peroxidase family
BB936_12210	COG4139	cobalamin transport
BB936_12225	COG0776	regulation of translation
BB936_12235	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BB936_12240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BB936_12245	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BB936_12250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BB936_12255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BB936_12260	COG4249	Peptidase C14 caspase catalytic subunit p20
BB936_12265	COG1811	Na channel or pump
BB936_12300	COG0803	Belongs to the bacterial solute-binding protein 9 family
BB936_12305	COG1121	(ABC) transporter
BB936_12310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB936_12315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB936_12330	COG1703	isobutyryl-CoA mutase activity
BB936_12335	COG1024	Enoyl-CoA hydratase
BB936_12340	COG0427	acetyl-CoA hydrolase
BB936_12345	COG0583	DNA-binding transcription factor activity
BB936_12355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB936_12360	COG3328	transposase activity
BB936_12365	COG1917	Cupin 2, conserved barrel domain protein
BB936_12370	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BB936_12375	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_12385	COG1175	transmembrane transport
BB936_12390	COG0395	ABC-type sugar transport system, permease component
BB936_12395	COG3842	ATPase activity
BB936_12400	COG1653	transport
BB936_12405	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BB936_12415	COG1988	membrane-bound metal-dependent
BB936_12425	COG3023	N-Acetylmuramoyl-L-alanine amidase
BB936_12435	COG0823	Involved in the tonB-independent uptake of proteins
BB936_12450	COG0501	Belongs to the peptidase M48B family
BB936_12455	COG0793	Belongs to the peptidase S41A family
BB936_12465	COG1956	GAF domain-containing protein
BB936_12470	COG2995	paraquat-inducible protein a
BB936_12475	COG3008	intermembrane lipid transfer
BB936_12485	COG2814	Major facilitator Superfamily
BB936_12535	COG0625	glutathione transferase activity
BB936_12540	COG0668	transmembrane transport
BB936_12565	COG2983	Belongs to the UPF0260 family
BB936_12570	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB936_12575	COG2951	lytic endotransglycosylase activity
BB936_12580	COG3100	YcgL domain-containing protein
BB936_12590	COG0850	regulation of cytokinetic process
BB936_12595	COG2894	cell division
BB936_12600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BB936_12605	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BB936_12610	COG0318	PFAM AMP-dependent synthetase and ligase
BB936_12625	COG1199	ATP-dependent helicase activity
BB936_12630	COG0251	oxidation-reduction process
BB936_12635	COG2076	Multidrug Resistance protein
BB936_12640	COG2076	Multidrug Resistance protein
BB936_12645	COG0800	Aldolase
BB936_12650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BB936_12655	COG1737	Transcriptional regulator
BB936_12660	COG0469	pyruvate kinase activity
BB936_12675	COG1560	Kdo2-lipid A biosynthetic process
BB936_12680	COG0739	heme binding
BB936_12685	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BB936_12690	COG1121	(ABC) transporter
BB936_12695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB936_12700	COG3104	oligopeptide transport
BB936_12705	COG2255	four-way junction helicase activity
BB936_12710	COG0632	four-way junction helicase activity
BB936_12715	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BB936_12720	COG0217	transcriptional regulatory protein
BB936_12725	COG0494	nUDIX hydrolase
BB936_12730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BB936_12735	COG1335	isochorismatase
BB936_12740	COG1801	Protein of unknown function DUF72
BB936_12745	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BB936_12750	COG2226	methyltransferase
BB936_12755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BB936_12775	COG0786	glutamate:sodium symporter activity
BB936_12780	COG1187	pseudouridine synthase activity
BB936_12800	COG1349	DNA-binding transcription factor activity
BB936_12810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_12820	COG3716	PTS system mannose fructose sorbose family IID component
BB936_12825	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_12840	COG4942	peptidase
BB936_12870	COG0402	S-adenosylhomocysteine deaminase activity
BB936_12880	COG1228	amidohydrolase
BB936_12910	COG2988	succinylglutamate desuccinylase activity
BB936_12915	COG3724	N-succinylarginine dihydrolase activity
BB936_12925	COG3138	arginine N-succinyltransferase
BB936_12930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB936_12935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB936_12940	COG1271	oxidase subunit
BB936_12945	COG1294	oxidase, subunit
BB936_12950	COG3850	Histidine kinase
BB936_12970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB936_12985	COG3713	MltA-interacting MipA family protein
BB936_12990	COG2766	serine protein kinase
BB936_12995	COG2718	Belongs to the UPF0229 family
BB936_13010	COG0583	DNA-binding transcription factor activity
BB936_13020	COG2200	EAL domain
BB936_13020	COG2202	Pas domain
BB936_13020	COG2199	diguanylate cyclase activity
BB936_13030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB936_13035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB936_13040	COG2719	SpoVR family
BB936_13045	COG2186	Transcriptional regulator
BB936_13050	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BB936_13055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BB936_13075	COG3142	Participates in the control of copper homeostasis
BB936_13080	COG3102	Protein conserved in bacteria
BB936_13085	COG0018	arginyl-trna synthetase
BB936_13095	COG1702	phosphate starvation-inducible protein PhoH
BB936_13110	COG3658	cytochrome
BB936_13115	COG1215	transferase activity, transferring glycosyl groups
BB936_13130	COG0006	proline dipeptidase activity
BB936_13140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BB936_13165	COG0577	efflux transmembrane transporter activity
BB936_13165	COG1136	(ABC) transporter
BB936_13175	COG1136	(ABC) transporter
BB936_13175	COG0577	efflux transmembrane transporter activity
BB936_13190	COG0672	)-iron permease
BB936_13205	COG2066	Belongs to the glutaminase family
BB936_13210	COG3622	Belongs to the hyi family
BB936_13215	COG0235	Class ii aldolase
BB936_13220	COG3395	kinase activity
BB936_13225	COG1349	DNA-binding transcription factor activity
BB936_13230	COG3290	protein histidine kinase activity
BB936_13235	COG4565	transcriptional regulatory protein
BB936_13240	COG3493	citrate carrier protein
BB936_13260	COG2223	nitrite transmembrane transporter activity
BB936_13265	COG0561	phosphatase activity
BB936_13275	COG3328	transposase activity
BB936_13280	COG0500	methyltransferase
BB936_13290	COG3328	transposase activity
BB936_13335	COG4974	Belongs to the 'phage' integrase family
BB936_13345	COG1276	copper resistance
BB936_13350	COG2372	response to copper ion
BB936_13355	COG1528	Iron-storage protein
BB936_13370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB936_13375	COG1770	oligopeptidase
BB936_13390	COG3141	response to X-ray
BB936_13395	COG0513	Belongs to the DEAD box helicase family
BB936_13405	COG3140	Belongs to the UPF0181 family
BB936_13415	COG0494	nUDIX hydrolase
BB936_13420	COG1760	l-serine dehydratase
BB936_13430	COG1253	flavin adenine dinucleotide binding
BB936_13435	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_13435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_13440	COG3715	PTS system
BB936_13445	COG3716	PTS system mannose fructose sorbose family IID component
BB936_13450	COG4811	Protein of unknown function (DUF986)
BB936_13455	COG1971	Probably functions as a manganese efflux pump
BB936_13465	COG5001	Diguanylate cyclase
BB936_13465	COG3447	MASE1 domain protein
BB936_13465	COG5002	protein histidine kinase activity
BB936_13475	COG2226	methyltransferase
BB936_13480	COG0768	penicillin binding
BB936_13490	COG1278	Cold shock
BB936_13535	COG2207	Transcriptional regulator
BB936_13555	COG1132	(ABC) transporter
BB936_13575	COG2203	Gaf domain
BB936_13575	COG5001	Diguanylate cyclase
BB936_13575	COG3706	GGDEF domain
BB936_13575	COG4251	negative regulation of phosphorylation
BB936_13590	COG3755	Protein conserved in bacteria
BB936_13615	COG1733	regulation of RNA biosynthetic process
BB936_13620	COG0702	epimerase
BB936_13625	COG2873	o-acetylhomoserine
BB936_13645	COG0840	transmembrane signaling receptor activity
BB936_13665	COG2211	Major facilitator Superfamily
BB936_13680	COG0538	isocitrate dehydrogenase activity
BB936_13715	COG0538	isocitrate dehydrogenase activity
BB936_13720	COG1187	pseudouridine synthase activity
BB936_13730	COG0482	sulfurtransferase activity
BB936_13735	COG2915	High frequency lysogenization protein hflD homolog
BB936_13740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BB936_13750	COG0745	RESPONSE REGULATOR receiver
BB936_13760	COG2850	peptidyl-arginine hydroxylation
BB936_13770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BB936_13780	COG4591	ABC-type transport system involved in lipoprotein release permease component
BB936_13790	COG4591	ABC-type transport system involved in lipoprotein release permease component
BB936_13795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BB936_13800	COG3134	Outer membrane lipoprotein
BB936_13805	COG1252	NADH dehydrogenase
BB936_13810	COG3150	esterase
BB936_13815	COG1472	Belongs to the glycosyl hydrolase 3 family
BB936_13825	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BB936_13830	COG5633	Lipoprotein
BB936_13835	COG0537	adenosine 5'-monophosphoramidase activity
BB936_13840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BB936_13850	COG0641	radical SAM
BB936_13870	COG1263	PTS System
BB936_13870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_13875	COG0084	hydrolase, TatD family'
BB936_13880	COG0470	DNA polymerase III
BB936_13885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BB936_13890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BB936_13895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB936_13900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB936_13910	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_13915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BB936_13920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB936_13925	COG0416	fatty acid biosynthetic process
BB936_13930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BB936_13935	COG1399	metal-binding, possibly nucleic acid-binding protein
BB936_13945	COG0564	pseudouridine synthase activity
BB936_13950	COG1530	ribonuclease E activity
BB936_13955	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BB936_13960	COG0418	dihydroorotase activity
BB936_13985	COG0628	permease
BB936_14020	COG1560	Kdo2-lipid A biosynthetic process
BB936_14030	COG2259	Doxx family
BB936_14040	COG2814	Major facilitator Superfamily
BB936_14045	COG3104	oligopeptide transport
BB936_14055	COG2943	transferase activity, transferring hexosyl groups
BB936_14060	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BB936_14080	COG3263	regulation of cellular component size
BB936_14090	COG3916	Acyl-homoserine-lactone synthase
BB936_14095	COG2771	luxR family
BB936_14100	COG4235	cytochrome complex assembly
BB936_14110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB936_14120	COG3301	Polysulphide reductase, NrfD
BB936_14125	COG0437	4 iron, 4 sulfur cluster binding
BB936_14130	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BB936_14145	COG2920	part of a sulfur-relay system
BB936_14150	COG1254	Belongs to the acylphosphatase family
BB936_14165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BB936_14170	COG3785	DNA binding
BB936_14175	COG1832	CoA-binding protein
BB936_14180	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BB936_14185	COG1803	Methylglyoxal synthase
BB936_14190	COG0210	DNA helicase
BB936_14195	COG3304	Inner membrane component domain
BB936_14200	COG1289	transmembrane transporter activity
BB936_14205	COG3070	regulator of competence-specific genes
BB936_14210	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
BB936_14215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BB936_14215	COG2885	chlorophyll binding
BB936_14220	COG3120	sequence-specific DNA binding
BB936_14225	COG1067	ATP-dependent peptidase activity
BB936_14230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BB936_14240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB936_14245	COG3009	Protein conserved in bacteria
BB936_14250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BB936_14250	COG3008	intermembrane lipid transfer
BB936_14255	COG2995	paraquat-inducible protein a
BB936_14260	COG0488	(ABC) transporter
BB936_14265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BB936_14265	COG0116	Belongs to the methyltransferase superfamily
BB936_14270	COG3217	Mosc domain protein beta barrel domain protein
BB936_14270	COG0633	Ferredoxin
BB936_14280	COG0167	dihydroorotate dehydrogenase activity
BB936_14285	COG0308	aminopeptidase N
BB936_14290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BB936_14295	COG0017	Asparaginyl-tRNA synthetase
BB936_14305	COG1448	Aminotransferase
BB936_14310	COG2200	EAL domain
BB936_14315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BB936_14320	COG3108	Peptidase M15
BB936_14325	COG2989	Protein conserved in bacteria
BB936_14330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BB936_14335	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BB936_14340	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BB936_14345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BB936_14350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BB936_14355	COG3173	Aminoglycoside phosphotransferase
BB936_14360	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BB936_14365	COG2835	tetraacyldisaccharide 4'-kinase activity
BB936_14370	COG1278	Cold shock
BB936_14375	COG1278	Cold shock
BB936_14380	COG5383	Protein conserved in bacteria
BB936_14385	COG1663	tetraacyldisaccharide 4'-kinase activity
BB936_14395	COG0658	competence protein
BB936_14395	COG2333	competence protein COMEC
BB936_14400	COG0776	regulation of translation
BB936_14405	COG0539	negative regulation of cytoplasmic translation
BB936_14410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BB936_14415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BB936_14420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BB936_14425	COG2323	membrane
BB936_14430	COG0252	asparaginase activity
BB936_14435	COG1944	ATP diphosphatase activity
BB936_14440	COG2116	formate transmembrane transporter activity
BB936_14445	COG1882	Formate acetyltransferase
BB936_14450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BB936_14455	COG2814	Major facilitator Superfamily
BB936_14460	COG3328	transposase activity
BB936_14475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BB936_14480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BB936_14485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BB936_14490	COG3107	peptidoglycan biosynthetic process
BB936_14490	COG1674	ftsk spoiiie
BB936_14495	COG1522	sequence-specific DNA binding
BB936_14500	COG0492	ferredoxin-NADP+ reductase activity
BB936_14510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BB936_14515	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BB936_14520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BB936_14525	COG0542	response to heat
BB936_14530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BB936_14535	COG1278	Cold shock
BB936_14545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB936_14550	COG2990	Protein conserved in bacteria
BB936_14555	COG3593	DNA synthesis involved in DNA repair
BB936_14560	COG2431	L-lysine efflux transmembrane transporter activity
BB936_14565	COG1151	hydroxylamine reductase activity
BB936_14570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB936_14575	COG0028	Belongs to the TPP enzyme family
BB936_14585	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BB936_14590	COG0702	epimerase
BB936_14595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB936_14605	COG1126	abc transporter atp-binding protein
BB936_14610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB936_14615	COG4215	(ABC) transporter
BB936_14620	COG4160	amino acid transport
BB936_14625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB936_14630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BB936_14640	COG1177	transmembrane transport
BB936_14645	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB936_14650	COG3842	ATPase activity
BB936_14655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BB936_14670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB936_14675	COG0569	domain protein
BB936_14675	COG2985	domain, Protein
BB936_14685	COG0671	phosphoesterase, PA-phosphatase related
BB936_14690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BB936_14695	COG1349	DNA-binding transcription factor activity
BB936_14700	COG0814	amino acid
BB936_14705	COG1760	l-serine dehydratase
BB936_14710	COG1686	Belongs to the peptidase S11 family
BB936_14720	COG0626	cystathionine gamma-synthase activity
BB936_14725	COG2011	ABC-type metal ion transport system permease component
BB936_14750	COG0625	glutathione transferase activity
BB936_14755	COG4771	TonB-dependent receptor
BB936_14765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB936_14770	COG0833	amino acid
BB936_14775	COG0583	DNA-binding transcription factor activity
BB936_14790	COG2855	membrane
BB936_14795	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BB936_14820	COG3710	Transcriptional regulator
BB936_14825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BB936_14825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BB936_14825	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BB936_14830	COG1105	Belongs to the carbohydrate kinase PfkB family
BB936_14845	COG3005	denitrification pathway
BB936_14850	COG0243	molybdopterin cofactor binding
BB936_14865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BB936_14870	COG1312	Catalyzes the dehydration of D-mannonate
BB936_14880	COG0246	Mannitol dehydrogenase
BB936_14885	COG2186	Transcriptional regulator
BB936_14895	COG0523	cobalamin synthesis protein
BB936_14900	COG0671	phosphoesterase, PA-phosphatase related
BB936_14905	COG0791	NLP P60 protein
BB936_14915	COG2200	EAL domain
BB936_14920	COG4166	transmembrane transport
BB936_14925	COG4174	ABC transporter (Permease)
BB936_14930	COG4239	(ABC) transporter, permease
BB936_14935	COG4172	Belongs to the ABC transporter superfamily
BB936_14945	COG2814	Major facilitator Superfamily
BB936_14950	COG1187	pseudouridine synthase activity
BB936_14955	COG1061	Type III restriction enzyme res subunit
BB936_14960	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BB936_14965	COG3081	Nucleoid-associated protein
BB936_14970	COG3082	Protein of unknown function (DUF1414)
BB936_14995	COG3328	transposase activity
BB936_15010	COG2801	Transposase and inactivated derivatives
BB936_15025	COG3338	carbonate dehydratase activity
BB936_15030	COG2723	6-phospho-beta-galactosidase activity
BB936_15035	COG1263	PTS System
BB936_15035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_15035	COG2190	(PTS) system
BB936_15040	COG1737	Transcriptional regulator
BB936_15095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BB936_15110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB936_15125	COG2223	nitrite transmembrane transporter activity
BB936_15130	COG0642	Histidine kinase
BB936_15130	COG2198	Histidine kinase
BB936_15135	COG2197	response regulator
BB936_15140	COG0784	Response regulator, receiver
BB936_15140	COG2205	protein histidine kinase activity
BB936_15150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BB936_15155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BB936_15170	COG4574	serine-type endopeptidase inhibitor activity
BB936_15190	COG0814	amino acid
BB936_15210	COG1441	menaquinone biosynthetic process
BB936_15215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BB936_15220	COG0596	Alpha beta hydrolase
BB936_15225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BB936_15230	COG1169	isochorismate synthase
BB936_15235	COG4575	ribosome binding
BB936_15240	COG0129	dihydroxy-acid dehydratase activity
BB936_15245	COG4702	Belongs to the UPF0303 family
BB936_15255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB936_15260	COG1609	Transcriptional regulator
BB936_15265	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_15270	COG3265	gluconokinase activity
BB936_15290	COG1007	ATP synthesis coupled electron transport
BB936_15295	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB936_15300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BB936_15305	COG0713	ATP synthesis coupled electron transport
BB936_15310	COG0839	Belongs to the complex I subunit 6 family
BB936_15315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB936_15320	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BB936_15325	COG1034	ATP synthesis coupled electron transport
BB936_15335	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BB936_15340	COG0649	NAD binding
BB936_15340	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB936_15345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB936_15350	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB936_15355	COG0583	DNA-binding transcription factor activity
BB936_15360	COG0436	Aminotransferase
BB936_15365	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BB936_15370	COG0471	metal ion transport
BB936_15370	COG0490	domain, Protein
BB936_15380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB936_15385	COG3013	Belongs to the UPF0304 family
BB936_15390	COG3092	negative regulation of chromosome organization
BB936_15400	COG0857	belongs to the CobB CobQ family
BB936_15400	COG0280	phosphate acetyltransferase
BB936_15405	COG1609	Transcriptional regulator
BB936_15410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_15420	COG3037	sugar-specific permease SgaT UlaA
BB936_15430	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BB936_15445	COG1090	epimerase
BB936_15455	COG4598	ABC transporter
BB936_15460	COG4160	amino acid transport
BB936_15465	COG4215	(ABC) transporter
BB936_15470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB936_15475	COG0163	prenyltransferase activity
BB936_15480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BB936_15485	COG1286	toxin biosynthetic process
BB936_15490	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BB936_15495	COG0285	dihydrofolate synthase activity
BB936_15500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BB936_15505	COG0586	Pfam SNARE associated Golgi protein
BB936_15515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BB936_15520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB936_15535	COG0697	spore germination
BB936_15540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB936_15545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB936_15570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BB936_15580	COG1609	Transcriptional regulator
BB936_15590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BB936_15595	COG2723	6-phospho-beta-galactosidase activity
BB936_15600	COG1447	Phosphotransferase system cellobiose-specific component IIA
BB936_15610	COG1794	racemase activity, acting on amino acids and derivatives
BB936_15620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB936_15625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB936_15625	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BB936_15635	COG3101	peptidyl-lysine hydroxylation
BB936_15640	COG0730	response to heat
BB936_15645	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BB936_15650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BB936_15655	COG2890	protein-(glutamine-N5) methyltransferase activity
BB936_15660	COG2840	Smr protein MutS2
BB936_15665	COG2062	phosphohistidine phosphatase, SixA
BB936_15670	COG1024	Enoyl-CoA hydratase
BB936_15670	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB936_15675	COG0183	Belongs to the thiolase family
BB936_15680	COG3691	Protein conserved in bacteria
BB936_15695	COG4235	cytochrome complex assembly
BB936_15695	COG3088	subunit of a heme lyase
BB936_15705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB936_15710	COG1138	Cytochrome C-type biogenesis protein
BB936_15715	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BB936_15720	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB936_15725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB936_15730	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB936_15745	COG2116	formate transmembrane transporter activity
BB936_15755	COG0582	viral genome integration into host DNA
BB936_15815	COG2824	Alkylphosphonate utilization operon protein PhnA
BB936_15820	COG1695	Transcriptional regulator
BB936_15830	COG2723	6-phospho-beta-galactosidase activity
BB936_15835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB936_15835	COG1263	PTS System
BB936_15840	COG1609	Transcriptional regulator
BB936_15845	COG2353	YceI-like domain
BB936_15850	COG3038	cytochrome b561
BB936_15855	COG2755	lipolytic protein G-D-S-L family
BB936_15855	COG0657	acetylesterase activity
BB936_15875	COG1127	ABC transporter
BB936_15880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BB936_15900	COG0531	amino acid
BB936_15905	COG2951	lytic endotransglycosylase activity
BB936_15935	COG1598	PFAM Uncharacterised protein family UPF0150
BB936_15940	COG3038	cytochrome b561
BB936_15945	COG0436	Aminotransferase
BB936_15965	COG3279	Response regulator of the LytR AlgR family
BB936_15975	COG0837	glucose binding
BB936_15990	COG3961	Belongs to the TPP enzyme family
BB936_15995	COG0667	Aldo Keto reductase
BB936_16005	COG1914	H( )-stimulated, divalent metal cation uptake system
BB936_16010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BB936_16040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB936_16065	COG3530	Putative quorum-sensing-regulated virulence factor
BB936_16070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BB936_16085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BB936_16090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_16095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB936_16100	COG2190	(PTS) system
BB936_16105	COG2205	protein histidine kinase activity
BB936_16110	COG0745	RESPONSE REGULATOR receiver
BB936_16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB936_16135	COG4208	sulfate ABC transporter
BB936_16140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BB936_16145	COG4150	thiosulfate binding
BB936_16155	COG1737	Transcriptional regulator
BB936_16160	COG2731	YhcH YjgK YiaL family protein
BB936_16175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB936_16185	COG2837	iron assimilation
BB936_16195	COG3111	PFAM Bacterial OB fold (BOF) protein
BB936_16200	COG0456	acetyltransferase
BB936_16205	COG0408	coproporphyrinogen oxidase activity
BB936_16210	COG1671	Belongs to the UPF0178 family
BB936_16225	COG0494	nUDIX hydrolase
BB936_16235	COG3043	anaerobic respiration
BB936_16240	COG0243	molybdopterin cofactor binding
BB936_16245	COG3062	negative regulation of establishment of protein localization
BB936_16255	COG2197	response regulator
BB936_16265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB936_16285	COG1393	Belongs to the ArsC family
BB936_16290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB936_16295	COG1876	peptidase activity
BB936_16340	COG0400	carboxylic ester hydrolase activity
BB936_16350	COG1444	tRNA N-acetyltransferase activity
BB936_16355	COG2707	UPF0756 membrane protein
BB936_16360	COG2321	neutral zinc metallopeptidase
BB936_16365	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BB936_16370	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BB936_16375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB936_16380	COG2716	regulation of RNA biosynthetic process
BB936_16385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BB936_16390	COG0628	permease
BB936_16395	COG4783	chaperone-mediated protein folding
BB936_16400	COG1393	Belongs to the ArsC family
BB936_16405	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BB936_16410	COG2233	PERMEase
BB936_16415	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BB936_16425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BB936_16430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB936_16445	COG0581	inorganic phosphate transmembrane transporter activity
BB936_16450	COG0573	inorganic phosphate transmembrane transporter activity
BB936_16455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BB936_16460	COG0248	Ppx GppA phosphatase
BB936_16475	COG5001	Diguanylate cyclase
BB936_16475	COG5002	protein histidine kinase activity
BB936_16475	COG3447	MASE1 domain protein
BB936_16480	COG0443	Heat shock 70 kDa protein
BB936_16485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB936_16495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB936_16500	COG0477	Major facilitator Superfamily
BB936_16505	COG2205	protein histidine kinase activity
BB936_16510	COG0745	RESPONSE REGULATOR receiver
BB936_16515	COG3422	double-strand break repair
BB936_16525	COG1597	lipid kinase activity
BB936_16530	COG3730	PTS system glucitol sorbitol-specific
BB936_16545	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_16550	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_16555	COG1349	DNA-binding transcription factor activity
BB936_16575	COG0351	phosphomethylpyrimidine kinase
BB936_16600	COG3328	transposase activity
BB936_16665	COG0519	Catalyzes the synthesis of GMP from XMP
BB936_16665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BB936_16670	COG0516	GMP reductase activity
BB936_16670	COG0517	IMP dehydrogenase activity
BB936_16675	COG1570	exodeoxyribonuclease VII activity
BB936_16680	COG1645	bacterial-type flagellum-dependent swarming motility
BB936_16695	COG1160	GTP binding
BB936_16705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB936_16715	COG0124	histidyl-tRNA synthetase
BB936_16720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BB936_16725	COG1426	Protein conserved in bacteria
BB936_16735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BB936_16750	COG4953	penicillin-binding protein 1C
BB936_16755	COG2373	Large extracellular alpha-helical protein
BB936_16760	COG3468	outer membrane autotransporter barrel domain protein
BB936_16775	COG2975	iron-sulfur cluster assembly
BB936_16780	COG0633	Ferredoxin
BB936_16785	COG0443	Heat shock 70 kDa protein
BB936_16790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BB936_16795	COG0316	Belongs to the HesB IscA family
BB936_16800	COG0822	iron-sulfur transferase activity
BB936_16810	COG1959	2 iron, 2 sulfur cluster binding
BB936_16815	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BB936_16820	COG0483	inositol monophosphate 1-phosphatase activity
BB936_16825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BB936_16830	COG3683	transport system, periplasmic component
BB936_16835	COG3711	transcriptional antiterminator
BB936_16840	COG2814	Major facilitator Superfamily
BB936_16845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB936_16850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB936_16850	COG1017	nitric oxide dioxygenase activity
BB936_16855	COG2188	Transcriptional regulator
BB936_16865	COG3457	Alanine racemase
BB936_16870	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BB936_16885	COG0347	Belongs to the P(II) protein family
BB936_16890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB936_16890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BB936_16895	COG2204	response regulator
BB936_16900	COG3170	Tfp pilus assembly protein FimV
BB936_16905	COG2205	protein histidine kinase activity
BB936_16920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BB936_16925	COG0590	tRNA wobble adenosine to inosine editing
BB936_16935	COG0560	Phosphoserine phosphatase
BB936_16945	COG1737	Transcriptional regulator
BB936_16950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BB936_16960	COG0736	holo-[acyl-carrier-protein] synthase activity
BB936_16965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BB936_16970	COG1381	Involved in DNA repair and RecF pathway recombination
BB936_16975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BB936_16980	COG0571	ribonuclease III activity
BB936_16985	COG0681	Belongs to the peptidase S26 family
BB936_16990	COG0481	GTPase activity
BB936_17000	COG3086	response to oxidative stress
BB936_17005	COG3026	antisigma factor binding
BB936_17010	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BB936_17020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BB936_17025	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BB936_17030	COG0513	Belongs to the DEAD box helicase family
BB936_17060	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
BB936_17065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BB936_17070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BB936_17075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BB936_17080	COG0497	DNA recombination
BB936_17085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB936_17095	COG2867	negative regulation of translational initiation
BB936_17100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BB936_17115	COG0659	secondary active sulfate transmembrane transporter activity
BB936_17120	COG3394	polysaccharide catabolic process
BB936_17125	COG2169	Transcriptional regulator
BB936_17125	COG1917	Cupin 2, conserved barrel domain protein
BB936_17130	COG1447	Phosphotransferase system cellobiose-specific component IIA
BB936_17135	COG2723	6-phospho-beta-galactosidase activity
BB936_17140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BB936_17145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BB936_17160	COG0667	Aldo Keto reductase
BB936_17170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BB936_17175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BB936_17185	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BB936_17190	COG4413	Urea transporter
BB936_17195	COG0829	nickel cation binding
BB936_17200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BB936_17205	COG0830	nickel cation binding
BB936_17215	COG0804	urea catabolic process
BB936_17220	COG0832	Belongs to the urease beta subunit family
BB936_17230	COG1124	(ABC) transporter
BB936_17240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB936_17275	COG1278	Cold shock
BB936_17295	COG0477	Major facilitator Superfamily
BB936_17300	COG2207	Transcriptional regulator
BB936_17315	COG4575	ribosome binding
BB936_17325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB936_17335	COG1780	Probably involved in ribonucleotide reductase function
BB936_17345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BB936_17355	COG4176	ABC-type proline glycine betaine transport system permease component
BB936_17360	COG2113	Glycine betaine
BB936_17370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB936_17375	COG0328	RNA-DNA hybrid ribonuclease activity
BB936_17380	COG2226	methyltransferase
BB936_17385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BB936_17390	COG0741	lytic transglycosylase activity
BB936_17390	COG1388	LysM domain
BB936_17400	COG3021	interspecies interaction between organisms
BB936_17405	COG2814	Major facilitator Superfamily
BB936_17410	COG0583	DNA-binding transcription factor activity
BB936_17415	COG0656	L-ascorbic acid biosynthetic process
BB936_17425	COG3328	transposase activity
BB936_17470	COG2011	ABC-type metal ion transport system permease component
BB936_17475	COG1464	Belongs to the NlpA lipoprotein family
BB936_17485	COG1720	tRNA m6t6A37 methyltransferase activity
BB936_17490	COG0442	prolyl-tRNA aminoacylation
BB936_17495	COG3015	lipoprotein NlpE involved in copper resistance
BB936_17505	COG4681	YaeQ
BB936_17515	COG4568	rho-dependent transcription termination
BB936_17525	COG0037	tRNA processing
BB936_17530	COG0346	lactoylglutathione lyase activity
BB936_17540	COG0825	malonyl-CoA metabolic process
BB936_17550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BB936_17555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BB936_17565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BB936_17570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BB936_17575	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BB936_17585	COG0750	zinc metalloprotease
BB936_17590	COG0575	Belongs to the CDS family
BB936_17595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BB936_17600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BB936_17605	COG0233	cytoplasmic translational termination
BB936_17610	COG0528	UMP kinase activity
BB936_17615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BB936_17620	COG0052	Belongs to the universal ribosomal protein uS2 family
BB936_17630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BB936_17635	COG2171	N-acyltransferase activity
BB936_17650	COG0564	pseudouridine synthase activity
BB936_17655	COG3098	single-species biofilm formation
BB936_17665	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BB936_17665	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BB936_17670	COG1611	Belongs to the LOG family
BB936_17675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB936_17685	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BB936_17690	COG2363	Small membrane protein
BB936_17695	COG0583	DNA-binding transcription factor activity
BB936_17705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB936_17710	COG2166	iron-sulfur cluster assembly
BB936_17715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BB936_17720	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BB936_17740	COG0860	N-Acetylmuramoyl-L-alanine amidase
BB936_17745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BB936_17745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BB936_17755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BB936_17760	COG1074	ATP-dependent DNA helicase activity
BB936_17765	COG1025	Belongs to the peptidase M16 family
BB936_17770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BB936_17775	COG4967	type IV pilus modification protein PilV
BB936_17795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BB936_17800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BB936_17820	COG3066	DNA modification
BB936_17825	COG0861	Integral membrane protein TerC family
BB936_17830	COG0667	Aldo Keto reductase
BB936_17840	COG0318	PFAM AMP-dependent synthetase and ligase
BB936_17840	COG0204	Acyl-transferase
BB936_17850	COG1609	Transcriptional regulator
BB936_17855	COG0019	diaminopimelate decarboxylase activity
BB936_17860	COG0583	DNA-binding transcription factor activity
BB936_17865	COG2814	Major facilitator Superfamily
BB936_17935	COG2165	general secretion pathway protein
BB936_17965	COG0288	reversible hydration of carbon dioxide
BB936_17970	COG1733	regulation of RNA biosynthetic process
BB936_17975	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_17985	COG0484	heat shock protein binding
BB936_17990	COG3706	GGDEF domain
BB936_17995	COG4319	ketosteroid isomerase
BB936_18010	COG3328	transposase activity
BB936_18015	COG2944	sequence-specific DNA binding
BB936_18045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BB936_18050	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BB936_18055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BB936_18060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BB936_18065	COG4974	Belongs to the 'phage' integrase family
BB936_18070	COG0716	FMN binding
BB936_18075	COG4452	Inner membrane protein CreD
BB936_18080	COG2205	protein histidine kinase activity
BB936_18085	COG0745	RESPONSE REGULATOR receiver
BB936_18095	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BB936_18100	COG0354	folic acid binding
BB936_18110	COG1272	protein, Hemolysin III
BB936_18120	COG1028	Short-chain dehydrogenase reductase Sdr
BB936_18135	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB936_18135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB936_18140	COG0509	glycine decarboxylation via glycine cleavage system
BB936_18145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BB936_18150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB936_18155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB936_18160	COG0006	proline dipeptidase activity
BB936_18165	COG3079	Belongs to the UPF0149 family
BB936_18170	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BB936_18180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BB936_18185	COG0148	phosphopyruvate hydratase activity
BB936_18190	COG0504	CTP synthase activity
BB936_18195	COG3956	TIGRFAM MazG family protein
BB936_18200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB936_18205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BB936_18210	COG3850	Histidine kinase
BB936_18210	COG2205	protein histidine kinase activity
BB936_18210	COG4999	Histidine kinase
BB936_18210	COG3437	response regulator, receiver
BB936_18215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB936_18220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BB936_18225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BB936_18235	COG2860	membrane
BB936_18240	COG0316	Belongs to the HesB IscA family
BB936_18250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BB936_18255	COG2223	nitrite transmembrane transporter activity
BB936_18260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB936_18265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BB936_18270	COG1120	ATPase activity
BB936_18275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB936_18280	COG1643	Atp-dependent helicase
BB936_18285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BB936_18290	COG1489	DNA binding
BB936_18295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BB936_18310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BB936_18315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BB936_18320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BB936_18325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BB936_18330	COG0726	polysaccharide deacetylase
BB936_18335	COG0842	Transport permease protein
BB936_18340	COG1131	(ABC) transporter
BB936_18345	COG0288	reversible hydration of carbon dioxide
BB936_18355	COG2132	Multicopper oxidase
BB936_18365	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BB936_18370	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BB936_18380	COG0697	spore germination
BB936_18385	COG3112	Uncharacterised protein family (UPF0231)
BB936_18400	COG4977	sequence-specific DNA binding
BB936_18410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB936_18415	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB936_18420	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BB936_18425	COG2186	Transcriptional regulator
BB936_18430	COG1113	amino acid transport
BB936_18435	COG3725	Membrane protein required for beta-lactamase induction
BB936_18450	COG4969	Belongs to the N-Me-Phe pilin family
BB936_18455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BB936_18460	COG1459	type II secretion system
BB936_18465	COG0516	GMP reductase activity
BB936_18470	COG0237	dephospho-CoA kinase activity
BB936_18480	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BB936_18485	COG0494	nUDIX hydrolase
BB936_18490	COG0653	protein targeting
BB936_18510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BB936_18515	COG0849	cell division
BB936_18520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BB936_18530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BB936_18535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BB936_18540	COG0772	Belongs to the SEDS family
BB936_18550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB936_18555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB936_18560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BB936_18565	COG0768	penicillin binding
BB936_18575	COG0275	rRNA processing
BB936_18580	COG2001	Belongs to the MraZ family
BB936_18590	COG1609	Transcriptional regulator
BB936_18600	COG0028	Belongs to the TPP enzyme family
BB936_18605	COG1022	Amp-dependent synthetase and ligase
BB936_18615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB936_18620	COG0473	3-isopropylmalate dehydrogenase activity
BB936_18625	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB936_18640	COG0814	amino acid
BB936_18645	COG2814	Major facilitator Superfamily
BB936_18655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BB936_18660	COG4533	DNA binding
BB936_18675	COG4143	(ABC) transporter
BB936_18680	COG1178	ABC-type Fe3 transport system permease component
BB936_18690	COG0586	Pfam SNARE associated Golgi protein
BB936_18695	COG0417	DNA replication proofreading
BB936_18700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BB936_18710	COG0564	pseudouridine synthase activity
BB936_18715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BB936_18720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BB936_18725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB936_18735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BB936_18740	COG2967	ApaG domain
BB936_18745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB936_18750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BB936_18755	COG3610	response to peptide
BB936_18760	COG2966	Psort location CytoplasmicMembrane, score
BB936_18765	COG1280	lysine exporter protein (LysE YggA)
BB936_18770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BB936_18775	COG0505	Belongs to the CarA family
BB936_18780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BB936_18785	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BB936_18790	COG1047	Peptidyl-prolyl cis-trans
BB936_18795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BB936_18800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BB936_18805	COG0196	riboflavin kinase activity
BB936_18815	COG0268	Binds directly to 16S ribosomal RNA
BB936_18820	COG0583	DNA-binding transcription factor activity
BB936_18825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BB936_18830	COG0484	heat shock protein binding
BB936_18835	COG0443	Heat shock 70 kDa protein
BB936_18840	COG1584	GPR1 FUN34 yaaH family protein
BB936_18855	COG0521	Mo-molybdopterin cofactor biosynthetic process
BB936_18860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BB936_18865	COG3022	response to hydroperoxide
BB936_18875	COG0083	homoserine kinase activity
BB936_18890	COG0745	RESPONSE REGULATOR receiver
BB936_18895	COG3045	CreA protein
BB936_18900	COG3708	Transcriptional regulator
BB936_18900	COG2207	Transcriptional regulator
BB936_18905	COG0406	alpha-ribazole phosphatase activity
BB936_18915	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BB936_18920	COG0741	lytic transglycosylase activity
BB936_18925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB936_18935	COG2199	diguanylate cyclase activity
BB936_18940	COG2885	chlorophyll binding
BB936_18945	COG0488	(ABC) transporter
BB936_18960	COG0604	alcohol dehydrogenase
BB936_18975	COG0560	Phosphoserine phosphatase
BB936_18980	COG3726	membrane protein affecting hemolysin expression
BB936_18985	COG0813	purine-nucleoside phosphorylase activity
BB936_18990	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BB936_18995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BB936_19000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BB936_19005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BB936_19010	COG0084	hydrolase, TatD family'
BB936_19015	COG4667	esterase of the alpha-beta hydrolase superfamily
BB936_19025	COG2823	Periplasmic or secreted lipoprotein
BB936_19030	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BB936_19035	COG0456	acetyltransferase
BB936_19040	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BB936_19045	COG2813	Specifically methylates the guanine in position
BB936_19050	COG0667	Aldo Keto reductase
BB936_19070	COG3706	GGDEF domain
BB936_19075	COG4772	TonB-dependent receptor
BB936_19110	COG3284	Transcriptional regulator
BB936_19140	COG2192	nodulation
BB936_19150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB936_19150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB936_19150	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BB936_19155	COG1461	Dihydroxyacetone kinase
BB936_19160	COG2376	Dihydroxyacetone kinase
BB936_19170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB936_19195	COG0859	PFAM glycosyl transferase family 9
BB936_19200	COG1070	Carbohydrate kinase
BB936_19205	COG2390	Transcriptional regulator
BB936_19210	COG1129	ABC transporter
BB936_19215	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB936_19220	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB936_19225	COG1879	ABC-type sugar transport system periplasmic component
BB936_19230	COG1830	Aldolase
BB936_19235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BB936_19250	COG3328	transposase activity
BB936_19280	COG0795	lipopolysaccharide-transporting ATPase activity
BB936_19285	COG0795	lipopolysaccharide-transporting ATPase activity
BB936_19290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BB936_19295	COG2927	DNA polymerase III (CHI subunit)
BB936_19310	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BB936_19320	COG2731	YhcH YjgK YiaL family protein
BB936_19330	COG0601	transmembrane transport
BB936_19340	COG0444	Belongs to the ABC transporter superfamily
BB936_19345	COG4608	Belongs to the ABC transporter superfamily
BB936_19375	COG2188	Transcriptional regulator
BB936_19380	COG3624	Phosphonate C-P lyase system protein PhnG
BB936_19385	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BB936_19390	COG3626	phosphonate metabolism
BB936_19395	COG3627	carbon phosphorus lyase activity
BB936_19400	COG4107	phosphonate C-P lyase system protein PhnK
BB936_19405	COG4778	phosphonate C-P lyase system protein PhnL
BB936_19410	COG3454	Phosphonate metabolism
BB936_19420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BB936_19425	COG0702	epimerase
BB936_19440	COG3787	Belongs to the UPF0306 family
BB936_19450	COG3842	ATPase activity
BB936_19455	COG0395	ABC-type sugar transport system, permease component
BB936_19465	COG1653	transport
BB936_19480	COG1982	Orn Lys Arg decarboxylase major
BB936_19485	COG0531	amino acid
BB936_19495	COG3153	acetyltransferase
BB936_19515	COG3681	Belongs to the UPF0597 family
BB936_19520	COG0814	amino acid
BB936_19530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB936_19540	COG0513	Belongs to the DEAD box helicase family
BB936_19550	COG1185	polyribonucleotide nucleotidyltransferase activity
BB936_19555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BB936_19560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BB936_19565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BB936_19570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BB936_19575	COG0195	Participates in both transcription termination and antitermination
BB936_19580	COG0779	Required for maturation of 30S ribosomal subunits
BB936_19595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB936_19600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BB936_19605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BB936_19610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB936_19615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BB936_19620	COG1534	Rna-binding protein
BB936_19625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB936_19630	COG2027	D-alanyl-D-alanine carboxypeptidase
BB936_19635	COG0745	RESPONSE REGULATOR receiver
BB936_19640	COG0642	Histidine kinase
BB936_19645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BB936_19650	COG0697	spore germination
BB936_19655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BB936_19660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BB936_19665	COG0142	geranyltranstransferase activity
BB936_19675	COG3423	Transcriptional regulator
BB936_19680	COG0039	L-malate dehydrogenase activity
BB936_19685	COG1438	arginine binding
BB936_19695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BB936_19700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BB936_19710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BB936_19715	COG2105	PFAM AIG2 family protein
BB936_19730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB936_19735	COG1253	flavin adenine dinucleotide binding
BB936_19745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BB936_19750	COG1218	3'(2'),5'-bisphosphate nucleotidase
BB936_19755	COG0737	Belongs to the 5'-nucleotidase family
BB936_19765	COG0545	Peptidyl-prolyl cis-trans isomerase
BB936_19770	COG3061	Opacity-associated protein A
BB936_19780	COG0359	binds to the 23S rRNA
BB936_19785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BB936_19790	COG2965	DNA replication, synthesis of RNA primer
BB936_19795	COG0360	Binds together with S18 to 16S ribosomal RNA
BB936_19805	COG1073	alpha beta
BB936_19810	COG3650	response to hydrogen peroxide
BB936_19815	COG1960	acyl-CoA dehydrogenase activity
BB936_19825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB936_19830	COG0557	exoribonuclease II activity
BB936_19835	COG1959	2 iron, 2 sulfur cluster binding
BB936_19840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BB936_19845	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BB936_19850	COG0330	HflC and HflK could
BB936_19855	COG0330	HflC and HflK could
BB936_19860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BB936_19865	COG1923	regulation of RNA biosynthetic process
BB936_19870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BB936_19875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BB936_19880	COG0860	N-Acetylmuramoyl-L-alanine amidase
BB936_19885	COG0802	atpase or kinase
BB936_19890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BB936_19890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BB936_19895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BB936_19910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BB936_19915	COG1162	GTPase activity
BB936_19920	COG0688	phosphatidylethanolamine metabolic process
BB936_19925	COG3264	Mechanosensitive ion channel
BB936_19925	COG1511	domain protein
BB936_19930	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BB936_19935	COG1053	succinate dehydrogenase
BB936_19940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BB936_19945	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BB936_19950	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BB936_19960	COG2076	Multidrug Resistance protein
BB936_19970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BB936_19990	COG0459	protein refolding
BB936_19995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BB936_20010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BB936_20020	COG4232	protein-disulfide reductase activity
BB936_20025	COG1929	Belongs to the glycerate kinase type-1 family
BB936_20030	COG1309	transcriptional regulator
BB936_20040	COG1882	Formate acetyltransferase
BB936_20045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BB936_20050	COG0814	amino acid
BB936_20055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB936_20065	COG3721	Heme iron utilization protein
BB936_20085	COG3720	iron ion transport
BB936_20090	COG4558	Periplasmic binding protein
BB936_20095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB936_20100	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BB936_20130	COG2161	toxin-antitoxin pair type II binding
BB936_20140	COG4178	(ABC) transporter
BB936_20145	COG4771	TonB-dependent receptor
BB936_20150	COG3712	iron ion homeostasis
BB936_20165	COG0425	Belongs to the sulfur carrier protein TusA family
BB936_20170	COG2391	methyltransferase activity
BB936_20330	COG2197	response regulator
BB936_20335	COG1301	dicarboxylic acid transport
BB936_20340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB936_20345	COG3162	membrane
BB936_20350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB936_20395	COG0138	bifunctional purine biosynthesis protein purh
BB936_20400	COG0151	Belongs to the GarS family
BB936_20415	COG3068	Protein conserved in bacteria
BB936_20420	COG1515	deoxyribonuclease V activity
BB936_20425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BB936_20430	COG2816	NAD+ diphosphatase activity
BB936_20435	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BB936_20440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BB936_20450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BB936_20455	COG2104	thiamine diphosphate biosynthetic process
BB936_20460	COG2022	thiamine diphosphate biosynthetic process
BB936_20475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BB936_20480	COG0085	RNA polymerase activity
BB936_20485	COG0222	ribosome binding
BB936_20490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BB936_20495	COG0081	regulation of translation
BB936_20500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BB936_20505	COG0250	Participates in transcription elongation, termination and antitermination
BB936_20510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB936_20515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BB936_20550	COG1072	(Pantothenic acid kinase))
BB936_20555	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BB936_20555	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BB936_20600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BB936_20605	COG1739	Uncharacterized protein family UPF0029
BB936_20610	COG0006	proline dipeptidase activity
BB936_20615	COG1024	Enoyl-CoA hydratase
BB936_20615	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB936_20620	COG0183	Belongs to the thiolase family
BB936_20630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BB936_20650	COG0805	protein transport
BB936_20655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB936_20660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB936_20665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BB936_20675	COG2226	methyltransferase
BB936_20685	COG0586	Pfam SNARE associated Golgi protein
BB936_20690	COG1966	Carbon starvation protein
BB936_20700	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BB936_20705	COG0412	Dienelactone hydrolase
BB936_20710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BB936_20715	COG0583	DNA-binding transcription factor activity
BB936_20725	COG0679	Auxin Efflux Carrier
BB936_20730	COG0584	glycerophosphoryl diester phosphodiesterase
BB936_20735	COG3842	ATPase activity
BB936_20740	COG0395	ABC-type sugar transport system, permease component
BB936_20745	COG1175	transmembrane transport
BB936_20750	COG1653	transport
BB936_20785	COG0410	ABC transporter
BB936_20790	COG0411	ABC transporter
BB936_20795	COG4177	L-phenylalanine transmembrane transporter activity
BB936_20800	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB936_20805	COG0683	leucine binding
BB936_20830	COG2177	Part of the ABC transporter FtsEX involved in
BB936_20835	COG2884	Cell division ATP-binding protein ftsE
BB936_20840	COG0552	protein localization to endoplasmic reticulum
BB936_20845	COG0742	ribosomal rna small subunit methyltransferase
BB936_20850	COG3776	membrane
BB936_20865	COG3714	YhhN family
BB936_20870	COG2217	Heavy metal translocating P-type atpase
BB936_20875	COG0425	Belongs to the sulfur carrier protein TusA family
BB936_20880	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BB936_20890	COG0247	lactate metabolic process
BB936_20895	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BB936_20900	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BB936_20905	COG2271	Major facilitator Superfamily
BB936_20910	COG0584	glycerophosphoryl diester phosphodiesterase
BB936_20915	COG0561	phosphatase activity
BB936_20920	COG2267	carboxylic ester hydrolase activity
BB936_20925	COG1280	lysine exporter protein (LysE YggA)
BB936_20930	COG1280	lysine exporter protein (LysE YggA)
BB936_20935	COG0514	ATP-dependent DNA helicase (RecQ)
BB936_20940	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BB936_20945	COG2050	protein possibly involved in aromatic compounds catabolism
BB936_20955	COG0598	Magnesium transport protein CorA
BB936_20960	COG5564	TIM-barrel signal transduction protein
BB936_20965	COG5441	Belongs to the UPF0261 family
BB936_20975	COG0210	DNA helicase
BB936_20980	COG1011	Hydrolase
BB936_20985	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BB936_20990	COG3159	Protein conserved in bacteria
BB936_20995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BB936_21000	COG5567	small periplasmic lipoprotein
BB936_21005	COG1965	Belongs to the frataxin family
BB936_21015	COG3072	Adenylate cyclase
BB936_21020	COG0181	hydroxymethylbilane synthase activity
BB936_21025	COG1587	Uroporphyrinogen-III synthase
BB936_21030	COG2959	enzyme of heme biosynthesis
BB936_21035	COG3071	HemY protein
BB936_21080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BB936_21085	COG2244	polysaccharide biosynthetic process
BB936_21090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BB936_21095	COG0456	acetyltransferase
BB936_21100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BB936_21105	COG1088	dTDP-glucose 4,6-dehydratase activity
BB936_21110	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BB936_21115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BB936_21120	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BB936_21125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB936_21135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BB936_21140	COG3118	belongs to the thioredoxin family
BB936_21150	COG0248	Ppx GppA phosphatase
BB936_21165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB936_21185	COG2860	membrane
BB936_21200	COG1758	RNA polymerase activity
BB936_21205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB936_21210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB936_21215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BB936_21225	COG0786	glutamate:sodium symporter activity
BB936_21230	COG2233	PERMEase
BB936_21235	COG2982	Protein involved in outer membrane biogenesis
BB936_21250	COG3423	Transcriptional regulator
BB936_21255	COG0456	acetyltransferase
BB936_21260	COG1490	D-aminoacyl-tRNA deacylase activity
BB936_21265	COG1295	ribonuclease BN
BB936_21270	COG1011	Hydrolase
BB936_21280	COG0174	glutamine synthetase
BB936_21290	COG3852	Histidine kinase
BB936_21300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB936_21305	COG3078	GTPase activator activity
BB936_21310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BB936_21315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB936_21315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BB936_21320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BB936_21325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BB936_21330	COG3084	Protein conserved in bacteria
BB936_21340	COG1763	Mo-molybdopterin cofactor biosynthetic process
BB936_21375	COG2186	Transcriptional regulator
BB936_21380	COG0477	Major facilitator Superfamily
BB936_21385	COG1609	Transcriptional regulator
BB936_21390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB936_21395	COG1879	ABC-type sugar transport system periplasmic component
BB936_21400	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB936_21410	COG1869	D-ribose catabolic process
BB936_21415	COG3158	transport of potassium into the cell
BB936_21420	COG0714	Associated with various cellular activities
BB936_21425	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BB936_21435	COG2502	aspartate--ammonia ligase
BB936_21440	COG1522	sequence-specific DNA binding
BB936_21445	COG0716	FMN binding
BB936_21450	COG0445	tRNA wobble uridine modification
BB936_21455	COG0357	Ribosomal RNA small subunit methyltransferase G
BB936_21460	COG3312	ion transport
BB936_21465	COG0356	it plays a direct role in the translocation of protons across the membrane
BB936_21475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BB936_21480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BB936_21485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BB936_21490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BB936_21495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BB936_21500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BB936_21505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BB936_21510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BB936_21515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BB936_21520	COG0573	inorganic phosphate transmembrane transporter activity
BB936_21525	COG0581	inorganic phosphate transmembrane transporter activity
BB936_21535	COG0704	Plays a role in the regulation of phosphate uptake
BB936_21545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB936_21550	COG0765	amino acid transport
BB936_21555	COG0765	amino acid transport
BB936_21565	COG2252	PERMEase
BB936_21575	COG4566	intracellular signal transduction
BB936_21585	COG0431	NADPH-dependent FMN reductase
BB936_21590	COG0840	transmembrane signaling receptor activity
BB936_21595	COG2011	ABC-type metal ion transport system permease component
BB936_21610	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BB936_21615	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BB936_21620	COG0706	membrane insertase activity
BB936_21630	COG0594	ribonuclease P activity
BB936_21635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BB936_22025	COG2831	hemolysin activation secretion protein
BB936_22030	COG3210	domain, Protein
BB936_22165	COG1388	LysM domain
BB936_22165	COG1470	cell adhesion involved in biofilm formation
BB936_22270	COG3328	transposase activity
BB936_22280	COG4886	Leucine-rich repeat (LRR) protein
BB936_22280	COG4886	Leucine-rich repeat (LRR) protein
BB936_22315	COG2801	Transposase and inactivated derivatives
BB936_22410	COG2963	transposase activity
BB936_22435	COG0431	NADPH-dependent FMN reductase
BB936_22440	COG0640	Transcriptional regulator
BB936_22520	COG1192	Involved in chromosome partitioning
BB936_22525	COG1475	DNA binding
BB936_22530	COG3609	addiction module antidote protein, CC2985 family
BB936_22645	COG4792	protein secretion
BB936_22650	COG4791	protein targeting
BB936_22655	COG4794	Type iii secretion
BB936_22660	COG4790	Type iii secretion