locus-tag	class	description
BED32_00020	COG3328	transposase activity
BED32_00030	COG4886	Leucine-rich repeat (LRR) protein
BED32_00030	COG4886	Leucine-rich repeat (LRR) protein
BED32_00065	COG2801	Transposase and inactivated derivatives
BED32_00160	COG0431	NADPH-dependent FMN reductase
BED32_00165	COG0640	Transcriptional regulator
BED32_00250	COG1192	Involved in chromosome partitioning
BED32_00255	COG1475	DNA binding
BED32_00260	COG3609	addiction module antidote protein, CC2985 family
BED32_00375	COG4792	protein secretion
BED32_00380	COG4791	protein targeting
BED32_00385	COG4794	Type iii secretion
BED32_00390	COG4790	Type iii secretion
BED32_00395	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BED32_00460	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BED32_00465	COG0592	DNA-directed DNA polymerase activity
BED32_00470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BED32_00475	COG0187	DNA topoisomerase II activity
BED32_00480	COG0561	phosphatase activity
BED32_00485	COG2423	ornithine cyclodeaminase activity
BED32_00495	COG0823	Involved in the tonB-independent uptake of proteins
BED32_00500	COG5645	(Lipo)protein
BED32_00530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BED32_00540	COG3074	FtsZ-dependent cytokinesis
BED32_00545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BED32_00550	COG1575	Belongs to the MenA family. Type 1 subfamily
BED32_00555	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BED32_00560	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BED32_00565	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BED32_00570	COG1609	Transcriptional regulator
BED32_00575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BED32_00580	COG0254	rRNA binding
BED32_00585	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BED32_00595	COG0527	aspartate kinase activity
BED32_00595	COG0460	homoserine dehydrogenase
BED32_00605	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BED32_00615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BED32_00620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BED32_00625	COG0165	Argininosuccinate lyase
BED32_00680	COG0678	peroxiredoxin activity
BED32_00680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BED32_00690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BED32_00695	COG1309	transcriptional regulator
BED32_00705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BED32_00715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BED32_00755	COG1879	ABC-type sugar transport system periplasmic component
BED32_00760	COG1129	ABC transporter
BED32_00765	COG1172	Belongs to the binding-protein-dependent transport system permease family
BED32_00770	COG1172	Belongs to the binding-protein-dependent transport system permease family
BED32_00775	COG0583	DNA-binding transcription factor activity
BED32_00780	COG3085	chromosome segregation
BED32_00795	COG3978	acetolactate synthase activity
BED32_00800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BED32_00805	COG0129	dihydroxy-acid dehydratase activity
BED32_00825	COG0583	DNA-binding transcription factor activity
BED32_00830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BED32_00855	COG3121	Chaperone
BED32_00875	COG3121	Chaperone
BED32_00890	COG1609	Transcriptional regulator
BED32_00915	COG3328	transposase activity
BED32_00925	COG3210	domain, Protein
BED32_00955	COG3851	Histidine kinase
BED32_00960	COG2197	response regulator
BED32_00965	COG2194	sulfuric ester hydrolase activity
BED32_00970	COG1764	response to oxidative stress
BED32_00980	COG0747	negative chemotaxis
BED32_00985	COG0601	transmembrane transport
BED32_00990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BED32_00995	COG0444	Belongs to the ABC transporter superfamily
BED32_01000	COG4608	Belongs to the ABC transporter superfamily
BED32_01005	COG2194	sulfuric ester hydrolase activity
BED32_01025	COG1192	Involved in chromosome partitioning
BED32_01030	COG1215	transferase activity, transferring glycosyl groups
BED32_01035	COG1215	transferase activity, transferring glycosyl groups
BED32_01040	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BED32_01045	COG0457	Tetratricopeptide repeat
BED32_01045	COG3118	belongs to the thioredoxin family
BED32_01055	COG2200	EAL domain
BED32_01055	COG2199	diguanylate cyclase activity
BED32_01060	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BED32_01075	COG1301	dicarboxylic acid transport
BED32_01080	COG0612	Peptidase, M16
BED32_01085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BED32_01090	COG1942	4-Oxalocrotonate Tautomerase
BED32_01095	COG2200	EAL domain
BED32_01105	COG2134	cdp-diacylglycerol pyrophosphatase
BED32_01110	COG1295	ribonuclease BN
BED32_01120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BED32_01125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BED32_01135	COG0742	ribosomal rna small subunit methyltransferase
BED32_01150	COG0589	response to stress
BED32_01165	COG0306	phosphate transporter
BED32_01170	COG2081	HI0933 family
BED32_01215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BED32_01235	COG1301	dicarboxylic acid transport
BED32_01250	COG3799	methylaspartate ammonia-lyase activity
BED32_01255	COG4865	methylaspartate mutase activity
BED32_01275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BED32_01275	COG1648	precorrin-2 dehydrogenase activity
BED32_01280	COG0583	DNA-binding transcription factor activity
BED32_01285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BED32_01285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BED32_01295	COG0561	phosphatase activity
BED32_01305	COG0583	DNA-binding transcription factor activity
BED32_01310	COG2814	Major facilitator Superfamily
BED32_01320	COG3718	enzyme involved in inositol metabolism
BED32_01330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BED32_01340	COG0673	inositol 2-dehydrogenase activity
BED32_01345	COG1082	Xylose isomerase domain protein TIM barrel
BED32_01350	COG1247	-acetyltransferase
BED32_01355	COG1741	Belongs to the pirin family
BED32_01360	COG1609	Transcriptional regulator
BED32_01365	COG2610	gluconate transmembrane transporter activity
BED32_01370	COG3265	gluconokinase activity
BED32_01375	COG2095	MarC family integral membrane protein
BED32_01380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BED32_01400	COG3275	phosphorelay sensor kinase activity
BED32_01405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BED32_01410	COG1523	belongs to the glycosyl hydrolase 13 family
BED32_01420	COG0297	glycogen (starch) synthase activity
BED32_01425	COG0058	SHG alpha-glucan phosphorylase activity
BED32_01430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BED32_01445	COG1349	DNA-binding transcription factor activity
BED32_01450	COG0705	Rhomboid family
BED32_01465	COG2909	trisaccharide binding
BED32_01470	COG0058	SHG alpha-glucan phosphorylase activity
BED32_01475	COG1640	4-alpha-glucanotransferase
BED32_01480	COG0316	Belongs to the HesB IscA family
BED32_01480	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BED32_01490	COG0596	Alpha beta hydrolase
BED32_01510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BED32_01515	COG1918	ferrous iron import across plasma membrane
BED32_01520	COG2183	response to ionizing radiation
BED32_01545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BED32_01550	COG0745	RESPONSE REGULATOR receiver
BED32_01560	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BED32_01570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BED32_01575	COG1011	Hydrolase
BED32_01585	COG0494	nUDIX hydrolase
BED32_01590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BED32_01615	COG4796	Type ii and iii secretion system protein
BED32_01620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BED32_01640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BED32_01650	COG0180	Tryptophanyl-tRNA synthetase
BED32_01655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BED32_01655	COG1648	precorrin-2 dehydrogenase activity
BED32_01665	COG2146	nitrite reductase [NAD(P)H] activity
BED32_01670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BED32_01675	COG0402	S-adenosylhomocysteine deaminase activity
BED32_01680	COG0738	Major facilitator superfamily
BED32_01690	COG1486	melibiose metabolic process
BED32_01695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BED32_01700	COG0433	COG0433 Predicted ATPase
BED32_01725	COG1765	OsmC-like protein
BED32_01730	COG3954	Phosphoribulokinase
BED32_01735	COG3089	Belongs to the UPF0270 family
BED32_01740	COG0429	hydrolase of the alpha beta-hydrolase fold
BED32_01755	COG4521	taurine ABC transporter
BED32_01765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BED32_01770	COG2175	clavaminate synthase activity
BED32_01780	COG1216	Glycosyl transferase, family 2
BED32_01785	COG0488	(ABC) transporter
BED32_01790	COG2249	NAD(P)H dehydrogenase (quinone) activity
BED32_01800	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BED32_01805	COG1047	Peptidyl-prolyl cis-trans
BED32_01810	COG2900	Belongs to the SlyX family
BED32_01815	COG0545	Peptidyl-prolyl cis-trans isomerase
BED32_01820	COG2964	Protein conserved in bacteria
BED32_01825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BED32_01830	COG2923	Belongs to the DsrF TusC family
BED32_01835	COG2168	tRNA wobble position uridine thiolation
BED32_01840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BED32_01845	COG0049	tRNA binding
BED32_01870	COG0051	transcription antitermination factor activity, RNA binding
BED32_01875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BED32_01880	COG0088	Forms part of the polypeptide exit tunnel
BED32_01885	COG0089	rRNA binding
BED32_01890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BED32_01895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BED32_01900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BED32_01905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BED32_01910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BED32_01915	COG0255	Belongs to the universal ribosomal protein uL29 family
BED32_01920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BED32_01925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BED32_01930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BED32_01935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BED32_01940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BED32_01950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BED32_01955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BED32_01960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BED32_01965	COG1841	ribosomal large subunit assembly
BED32_01970	COG0200	Binds to the 23S rRNA
BED32_01975	COG0201	protein transport
BED32_01980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BED32_01990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BED32_01995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BED32_02000	COG0202	RNA polymerase activity
BED32_02005	COG0203	ribosomal protein L17
BED32_02015	COG0789	Transcriptional regulator
BED32_02020	COG3036	rescue of stalled ribosome
BED32_02030	COG1970	mechanosensitive ion channel activity
BED32_02035	COG0569	domain protein
BED32_02040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BED32_02040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BED32_02045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BED32_02050	COG0242	peptide deformylase activity
BED32_02055	COG0758	DNA mediated transformation
BED32_02065	COG0551	DNA topoisomerase type I activity
BED32_02070	COG0009	L-threonylcarbamoyladenylate synthase
BED32_02075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BED32_02080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BED32_02115	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BED32_02120	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BED32_02125	COG2224	Isocitrate lyase
BED32_02130	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BED32_02135	COG1414	Transcriptional regulator
BED32_02160	COG0527	aspartate kinase activity
BED32_02165	COG0166	Belongs to the GPI family
BED32_02180	COG3833	ABC-type maltose transport systems, permease component
BED32_02190	COG2182	Extracellular solute-binding protein
BED32_02200	COG4580	involved in the transport of maltose and maltodextrins
BED32_02215	COG3161	chorismate lyase activity
BED32_02220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BED32_02225	COG2937	Belongs to the GPAT DAPAT family
BED32_02230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BED32_02235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BED32_02240	COG3237	CsbD-like
BED32_02245	COG0735	belongs to the Fur family
BED32_02250	COG2755	lipolytic protein G-D-S-L family
BED32_02250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BED32_02255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BED32_02275	COG0305	Participates in initiation and elongation during chromosome replication
BED32_02285	COG1448	Aminotransferase
BED32_02290	COG2315	Protein conserved in bacteria
BED32_02295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BED32_02305	COG3550	peptidyl-serine autophosphorylation
BED32_02320	COG2252	PERMEase
BED32_02325	COG0025	NhaP-type Na H and K H
BED32_02330	COG0583	DNA-binding transcription factor activity
BED32_02335	COG1380	Effector of murein hydrolase LrgA
BED32_02345	COG1126	abc transporter atp-binding protein
BED32_02350	COG0765	amino acid transport
BED32_02355	COG4597	amino acid ABC transporter
BED32_02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BED32_02375	COG1560	Kdo2-lipid A biosynthetic process
BED32_02380	COG0471	metal ion transport
BED32_02385	COG1278	Cold shock
BED32_02390	COG1278	Cold shock
BED32_02395	COG3133	Outer membrane lipoprotein
BED32_02405	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BED32_02410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BED32_02415	COG2264	protein methyltransferase activity
BED32_02420	COG4145	pantothenate transmembrane transporter activity
BED32_02425	COG3924	membrane
BED32_02430	COG0439	Biotin carboxylase
BED32_02435	COG0511	ligase activity, forming carbon-carbon bonds
BED32_02440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BED32_02445	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BED32_02455	COG0604	alcohol dehydrogenase
BED32_02460	COG2200	EAL domain
BED32_02460	COG2199	diguanylate cyclase activity
BED32_02465	COG1077	Cell shape determining protein MreB Mrl
BED32_02470	COG1792	Involved in formation and maintenance of cell shape
BED32_02475	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BED32_02485	COG1530	ribonuclease E activity
BED32_02490	COG3164	Protein of unknown function
BED32_02495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BED32_02500	COG0312	modulator of DNA gyrase
BED32_02555	COG0583	DNA-binding transcription factor activity
BED32_02565	COG1566	PFAM secretion protein HlyD family protein
BED32_02570	COG1289	transmembrane transporter activity
BED32_02585	COG2732	(Barnase) inhibitor
BED32_02590	COG3028	Belongs to the UPF0307 family
BED32_02595	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BED32_02770	COG0312	modulator of DNA gyrase
BED32_02780	COG3783	Cytochrome b(562)
BED32_02785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BED32_02815	COG3964	amidohydrolase
BED32_02835	COG3711	transcriptional antiterminator
BED32_02835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_02840	COG3093	addiction module antidote protein HigA
BED32_02865	COG0366	Alpha amylase catalytic
BED32_02885	COG2308	Evidence 4 Homologs of previously reported genes of
BED32_02895	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BED32_02900	COG0540	Belongs to the ATCase OTCase family
BED32_02905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_02910	COG1660	Displays ATPase and GTPase activities
BED32_02915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_02925	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BED32_02930	COG1137	ATPase activity
BED32_02935	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BED32_02940	COG3117	lipopolysaccharide transmembrane transporter activity
BED32_02945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BED32_02950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BED32_02950	COG0517	IMP dehydrogenase activity
BED32_02960	COG1127	ABC transporter
BED32_02965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BED32_02970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BED32_02975	COG2854	intermembrane phospholipid transfer
BED32_02980	COG3113	response to antibiotic
BED32_02985	COG5007	Belongs to the BolA IbaG family
BED32_02990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BED32_02995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BED32_03000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BED32_03005	COG3105	Protein conserved in bacteria
BED32_03010	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BED32_03015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BED32_03020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BED32_03025	COG0625	glutathione transferase activity
BED32_03030	COG2969	positive regulation of protein catabolic process
BED32_03045	COG0493	'glutamate synthase
BED32_03050	COG0070	glutamate synthase
BED32_03050	COG0069	glutamate synthase activity
BED32_03050	COG0067	glutamate synthase
BED32_03055	COG1242	4 iron, 4 sulfur cluster binding
BED32_03060	COG2198	Histidine kinase
BED32_03060	COG0784	Response regulator, receiver
BED32_03060	COG5002	protein histidine kinase activity
BED32_03065	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BED32_03070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BED32_03075	COG2823	Periplasmic or secreted lipoprotein
BED32_03080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BED32_03085	COG0792	nuclease activity
BED32_03095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BED32_03150	COG3121	Chaperone
BED32_03155	COG3188	usher protein
BED32_03170	COG0667	Aldo Keto reductase
BED32_03175	COG1064	alcohol dehydrogenase
BED32_03180	COG1741	Belongs to the pirin family
BED32_03185	COG0583	DNA-binding transcription factor activity
BED32_03190	COG0435	Glutathione S-transferase
BED32_03195	COG2259	Doxx family
BED32_03205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BED32_03210	COG4575	ribosome binding
BED32_03225	COG0586	Pfam SNARE associated Golgi protein
BED32_03245	COG1904	glucuronate isomerase
BED32_03250	COG0246	Mannitol dehydrogenase
BED32_03255	COG2721	sulfolactate sulfo-lyase activity
BED32_03265	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BED32_03270	COG0861	Integral membrane protein TerC family
BED32_03280	COG0673	inositol 2-dehydrogenase activity
BED32_03285	COG1451	nucleotide metabolic process
BED32_03305	COG2813	Specifically methylates the guanine in position
BED32_03315	COG0446	pyridine nucleotide-disulphide oxidoreductase
BED32_03315	COG1902	pentaerythritol trinitrate reductase activity
BED32_03325	COG3247	response to pH
BED32_03335	COG0076	glutamate decarboxylase activity
BED32_03340	COG0531	amino acid
BED32_03355	COG3328	transposase activity
BED32_03360	COG1263	PTS System
BED32_03360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_03365	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BED32_03375	COG1472	Belongs to the glycosyl hydrolase 3 family
BED32_03385	COG3876	Protein conserved in bacteria
BED32_03400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BED32_03405	COG0358	DNA primase activity
BED32_03415	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BED32_03420	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BED32_03425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BED32_03430	COG1968	undecaprenyl-diphosphatase activity
BED32_03435	COG0617	tRNA 3'-terminal CCA addition
BED32_03440	COG4991	sh3 domain protein
BED32_03445	COG3025	triphosphatase activity
BED32_03450	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BED32_03455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BED32_03455	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BED32_03460	COG0531	amino acid
BED32_03470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BED32_03475	COG3384	dioxygenase
BED32_03480	COG0754	glutathionylspermidine amidase activity
BED32_03485	COG5463	Belongs to the UPF0441 family
BED32_03495	COG1538	Outer membrane efflux protein
BED32_03500	COG0494	nUDIX hydrolase
BED32_03505	COG3151	Protein conserved in bacteria
BED32_03510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BED32_03515	COG3150	esterase
BED32_03520	COG0187	DNA topoisomerase II activity
BED32_03530	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BED32_03535	COG2249	NAD(P)H dehydrogenase (quinone) activity
BED32_03540	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BED32_03545	COG0204	Acyl-transferase
BED32_03550	COG2132	Multicopper oxidase
BED32_03560	COG0656	L-ascorbic acid biosynthetic process
BED32_03565	COG1979	alcohol dehydrogenase
BED32_03570	COG2207	Transcriptional regulator
BED32_03575	COG0586	Pfam SNARE associated Golgi protein
BED32_03580	COG0626	cystathionine gamma-synthase activity
BED32_03585	COG0811	peptide transport
BED32_03590	COG0848	biopolymer transport protein
BED32_03640	COG4964	Belongs to the GSP D family
BED32_03665	COG3145	DNA-N1-methyladenine dioxygenase activity
BED32_03670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BED32_03680	COG2135	peptidase activity
BED32_03700	COG2963	transposase activity
BED32_03720	COG1136	(ABC) transporter
BED32_03720	COG0577	efflux transmembrane transporter activity
BED32_03735	COG2801	Transposase and inactivated derivatives
BED32_03755	COG1120	ATPase activity
BED32_03760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BED32_03765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BED32_03770	COG4592	Periplasmic binding protein
BED32_03780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BED32_03785	COG0840	transmembrane signaling receptor activity
BED32_03800	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BED32_03830	COG2204	response regulator
BED32_03835	COG1677	Flagellar hook-basal body complex protein FliE
BED32_03880	COG1815	bacterial-type flagellum-dependent cell motility
BED32_03885	COG1558	bacterial-type flagellum-dependent cell motility
BED32_03890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BED32_03895	COG1749	Flagellar hook protein flgE
BED32_03905	COG4786	Flagellar basal body rod
BED32_03915	COG1706	bacterial-type flagellum-dependent cell motility
BED32_03950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BED32_03960	COG1516	flagellar protein fliS
BED32_03980	COG1191	sigma factor activity
BED32_03985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BED32_03995	COG3133	Outer membrane lipoprotein
BED32_04000	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BED32_04005	COG0437	4 iron, 4 sulfur cluster binding
BED32_04010	COG5557	Pfam Polysulphide reductase, NrfD
BED32_04015	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BED32_04020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BED32_04025	COG1773	rubredoxin
BED32_04030	COG0375	protein maturation
BED32_04035	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BED32_04040	COG0298	carbon dioxide binding
BED32_04045	COG0409	Hydrogenase expression formation protein
BED32_04050	COG0309	Hydrogenase expression formation protein (HypE)
BED32_04055	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BED32_04065	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BED32_04080	COG5001	Diguanylate cyclase
BED32_04085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_04100	COG0477	Major facilitator Superfamily
BED32_04115	COG1283	sodium-dependent phosphate transmembrane transporter activity
BED32_04125	COG1609	Transcriptional regulator
BED32_04135	COG0477	Major facilitator Superfamily
BED32_04145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BED32_04165	COG4607	ABC-type enterochelin transport system periplasmic component
BED32_04175	COG4605	iron ion homeostasis
BED32_04185	COG0024	Methionine aminopeptidase
BED32_04210	COG1289	transmembrane transporter activity
BED32_04220	COG1982	Orn Lys Arg decarboxylase major
BED32_04225	COG0531	amino acid
BED32_04265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BED32_04280	COG1982	Orn Lys Arg decarboxylase major
BED32_04290	COG0741	lytic transglycosylase activity
BED32_04295	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BED32_04300	COG1194	a g-specific adenine glycosylase
BED32_04305	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BED32_04310	COG3171	Protein conserved in bacteria
BED32_04315	COG2066	Belongs to the glutaminase family
BED32_04325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BED32_04330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BED32_04335	COG1872	DUF167
BED32_04340	COG0762	integral membrane protein
BED32_04345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BED32_04350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BED32_04355	COG2805	Type II/IV secretion system protein
BED32_04365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BED32_04370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BED32_04375	COG1678	Uncharacterized ACR, COG1678
BED32_04380	COG0189	ligase activity
BED32_04385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BED32_04390	COG2356	endonuclease I
BED32_04395	COG3091	SprT-like family
BED32_04400	COG0640	Transcriptional regulator
BED32_04405	COG3328	transposase activity
BED32_04420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BED32_04425	COG1166	arginine decarboxylase activity
BED32_04435	COG0501	Belongs to the peptidase M48B family
BED32_04440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BED32_04445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BED32_04450	COG0126	phosphoglycerate kinase activity
BED32_04455	COG0191	fructose-bisphosphate aldolase activity
BED32_04475	COG1279	arginine transmembrane transporter activity
BED32_04485	COG0583	DNA-binding transcription factor activity
BED32_04490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BED32_04495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BED32_04530	COG0602	queuosine metabolic process
BED32_04550	COG0720	synthase
BED32_04555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BED32_04560	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BED32_04565	COG0175	sulfate reduction
BED32_04580	COG2234	aminopeptidase activity
BED32_04585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BED32_04585	COG1648	precorrin-2 dehydrogenase activity
BED32_04590	COG0175	sulfate reduction
BED32_04595	COG2895	sulfate adenylyltransferase (ATP) activity
BED32_04600	COG0529	Catalyzes the synthesis of activated sulfate
BED32_04610	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BED32_04620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BED32_04625	COG0585	pseudouridine synthase activity
BED32_04630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BED32_04635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BED32_04640	COG1388	LysM domain
BED32_04640	COG4942	peptidase
BED32_04645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BED32_04650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BED32_04675	COG3188	usher protein
BED32_04680	COG3121	Chaperone
BED32_04690	COG3539	Fimbrial protein
BED32_04695	COG3539	Fimbrial protein
BED32_04725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_04735	COG1538	Outer membrane efflux protein
BED32_04755	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_04760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BED32_04765	COG1858	cytochrome C peroxidase
BED32_04775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BED32_04780	COG0640	Transcriptional regulator
BED32_04835	COG0410	ABC transporter
BED32_04840	COG1137	ATPase activity
BED32_04845	COG4177	L-phenylalanine transmembrane transporter activity
BED32_04850	COG0559	Belongs to the binding-protein-dependent transport system permease family
BED32_04860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BED32_04860	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BED32_04865	COG0243	molybdopterin cofactor binding
BED32_04870	COG0437	4 iron, 4 sulfur cluster binding
BED32_04875	COG3302	dmso reductase anchor subunit
BED32_04880	COG3381	protein complex oligomerization
BED32_04900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BED32_04905	COG2137	regulation of response to DNA damage stimulus
BED32_04910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BED32_04915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BED32_04935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BED32_04945	COG2918	glutathione biosynthetic process
BED32_04950	COG1854	S-ribosylhomocysteine lyase activity
BED32_04955	COG4536	flavin adenine dinucleotide binding
BED32_04970	COG4137	Cytochrome C assembly protein
BED32_04975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BED32_04980	COG0228	four-way junction DNA binding
BED32_04985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BED32_04990	COG0336	Belongs to the RNA methyltransferase TrmD family
BED32_04995	COG0335	large ribosomal subunit rRNA binding
BED32_05005	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BED32_05010	COG3279	Response regulator of the LytR AlgR family
BED32_05015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BED32_05020	COG1605	Chorismate mutase
BED32_05020	COG0287	Prephenate dehydrogenase
BED32_05025	COG0077	Prephenate dehydratase
BED32_05025	COG1605	Chorismate mutase
BED32_05035	COG0542	response to heat
BED32_05045	COG0564	pseudouridine synthase activity
BED32_05050	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BED32_05060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BED32_05065	COG3328	transposase activity
BED32_05070	COG3547	Transposase (IS116 IS110 IS902 family)
BED32_05100	COG5544	Lipoprotein
BED32_05105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BED32_05110	COG1042	CoA-binding domain protein
BED32_05110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BED32_05110	COG0045	succinate-CoA ligase (ADP-forming) activity
BED32_05120	COG3118	belongs to the thioredoxin family
BED32_05125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BED32_05130	COG2814	Major facilitator Superfamily
BED32_05135	COG1566	PFAM secretion protein HlyD family protein
BED32_05140	COG1538	Outer membrane efflux protein
BED32_05145	COG1846	Transcriptional regulator
BED32_05155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BED32_05160	COG2814	Major facilitator Superfamily
BED32_05195	COG0765	amino acid transport
BED32_05200	COG0765	amino acid transport
BED32_05225	COG0436	Aminotransferase
BED32_05230	COG0582	viral genome integration into host DNA
BED32_05285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BED32_05365	COG1484	DNA-dependent DNA replication
BED32_05465	COG5410	chromosome segregation
BED32_05600	COG0235	Class ii aldolase
BED32_05605	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BED32_05610	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BED32_05615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BED32_05620	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BED32_05640	COG1960	acyl-CoA dehydrogenase activity
BED32_05650	COG0121	glutamine amidotransferase
BED32_05655	COG3034	peptidoglycan biosynthetic process
BED32_05660	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BED32_05665	COG1805	sodium ion transport
BED32_05670	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BED32_05675	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BED32_05685	COG2871	sodium ion transport
BED32_05690	COG1477	protein flavinylation
BED32_05695	COG2991	Protein conserved in bacteria
BED32_05705	COG1181	Belongs to the D-alanine--D-alanine ligase family
BED32_05710	COG2964	Protein conserved in bacteria
BED32_05725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BED32_05730	COG2195	Cleaves the N-terminal amino acid of tripeptides
BED32_05735	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BED32_05755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BED32_05760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BED32_05765	COG2188	Transcriptional regulator
BED32_05785	COG3459	Glycosyltransferase 36 associated
BED32_05800	COG2226	methyltransferase
BED32_05825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BED32_05830	COG3123	guanosine phosphorylase activity
BED32_05835	COG2974	May be involved in recombination
BED32_05840	COG1940	carbohydrate kinase activity
BED32_05845	COG0419	ATPase involved in DNA repair
BED32_05850	COG0420	3'-5' exonuclease activity
BED32_05855	COG0745	RESPONSE REGULATOR receiver
BED32_05860	COG5002	protein histidine kinase activity
BED32_05870	COG1114	Component of the transport system for branched-chain amino acids
BED32_05880	COG0366	Alpha amylase catalytic
BED32_05900	COG0450	alkyl hydroperoxide reductase
BED32_05905	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BED32_05910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BED32_05920	COG0343	queuine tRNA-ribosyltransferase activity
BED32_05925	COG1862	Preprotein translocase
BED32_05930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BED32_05935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BED32_05950	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BED32_05955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BED32_05955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BED32_05960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BED32_05965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BED32_05970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BED32_05975	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BED32_05985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BED32_05990	COG0142	geranyltranstransferase activity
BED32_06000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BED32_06000	COG0301	tRNA thio-modification
BED32_06005	COG0693	protein deglycase activity
BED32_06010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BED32_06015	COG1666	GTP binding
BED32_06020	COG2814	Major facilitator Superfamily
BED32_06025	COG0109	protoheme IX farnesyltransferase activity
BED32_06030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BED32_06035	COG1845	cytochrome c oxidase, subunit III
BED32_06040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BED32_06045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BED32_06055	COG2223	nitrite transmembrane transporter activity
BED32_06060	COG3056	Lipoprotein
BED32_06065	COG0271	Belongs to the BolA IbaG family
BED32_06075	COG0544	peptidyl-prolyl cis-trans isomerase activity
BED32_06080	COG0740	serine-type endopeptidase activity
BED32_06085	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BED32_06090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BED32_06095	COG0776	regulation of translation
BED32_06100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BED32_06105	COG1555	photosystem II stabilization
BED32_06110	COG0824	Thioesterase
BED32_06115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BED32_06120	COG4533	DNA binding
BED32_06125	COG0561	phosphatase activity
BED32_06135	COG1522	sequence-specific DNA binding
BED32_06140	COG1132	(ABC) transporter
BED32_06145	COG1132	(ABC) transporter
BED32_06150	COG0347	Belongs to the P(II) protein family
BED32_06155	COG0004	ammonium transporteR
BED32_06160	COG1946	Acyl-CoA thioesterase
BED32_06165	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BED32_06170	COG3695	enzyme binding
BED32_06200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BED32_06205	COG0803	Belongs to the bacterial solute-binding protein 9 family
BED32_06210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BED32_06215	COG0254	rRNA binding
BED32_06230	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BED32_06235	COG3457	Alanine racemase
BED32_06245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BED32_06250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_06255	COG1309	transcriptional regulator
BED32_06260	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BED32_06280	COG2832	Protein of unknown function (DUF454)
BED32_06285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BED32_06295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BED32_06300	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BED32_06305	COG0326	Molecular chaperone. Has ATPase activity
BED32_06310	COG0563	adenylate kinase activity
BED32_06315	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BED32_06325	COG1216	Glycosyl transferase, family 2
BED32_06325	COG1442	glycosyl transferase family 8
BED32_06330	COG1215	transferase activity, transferring glycosyl groups
BED32_06335	COG0438	transferase activity, transferring glycosyl groups
BED32_06340	COG0438	transferase activity, transferring glycosyl groups
BED32_06345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BED32_06365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BED32_06370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BED32_06370	COG4651	solute:proton antiporter activity
BED32_06375	COG2223	nitrite transmembrane transporter activity
BED32_06390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BED32_06395	COG3735	TraB family
BED32_06400	COG2217	Heavy metal translocating P-type atpase
BED32_06405	COG0789	Transcriptional regulator
BED32_06410	COG1585	Membrane protein implicated in regulation of membrane protease activity
BED32_06415	COG0330	HflC and HflK could
BED32_06420	COG3118	belongs to the thioredoxin family
BED32_06425	COG0300	oxidoreductase activity
BED32_06430	COG2755	lipolytic protein G-D-S-L family
BED32_06435	COG4181	ATPase activity
BED32_06440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BED32_06445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BED32_06450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BED32_06455	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BED32_06460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BED32_06465	COG0215	cysteine-tRNA ligase activity
BED32_06470	COG2501	S4 domain
BED32_06475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BED32_06485	COG0582	viral genome integration into host DNA
BED32_06535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BED32_06600	COG1484	DNA-dependent DNA replication
BED32_06760	COG4386	tail sheath protein
BED32_06825	COG0582	viral genome integration into host DNA
BED32_06950	COG0305	Participates in initiation and elongation during chromosome replication
BED32_07000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BED32_07040	COG3772	lysozyme
BED32_07205	COG0582	viral genome integration into host DNA
BED32_07210	COG0582	viral genome integration into host DNA
BED32_07215	COG0582	viral genome integration into host DNA
BED32_07230	COG3177	Filamentation induced by cAMP protein fic
BED32_07315	COG2850	peptidyl-arginine hydroxylation
BED32_07330	COG5265	(ABC) transporter
BED32_07345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BED32_07360	COG1278	Cold shock
BED32_07365	COG1278	Cold shock
BED32_07370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BED32_07375	COG3706	GGDEF domain
BED32_07380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BED32_07385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BED32_07390	COG0321	lipoyl(octanoyl) transferase activity
BED32_07395	COG2921	Belongs to the UPF0250 family
BED32_07400	COG1686	Belongs to the peptidase S11 family
BED32_07405	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BED32_07410	COG0772	Belongs to the SEDS family
BED32_07415	COG0768	penicillin binding
BED32_07425	COG0799	negative regulation of ribosome biogenesis
BED32_07430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BED32_07435	COG1466	dna polymerase III delta subunit
BED32_07440	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BED32_07445	COG0495	leucyl-tRNA aminoacylation
BED32_07450	COG2888	peptidyl-tyrosine sulfation
BED32_07455	COG1126	abc transporter atp-binding protein
BED32_07460	COG0765	amino acid transport
BED32_07465	COG0765	amino acid transport
BED32_07480	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BED32_07485	COG4535	Mg2 and Co2 transporter CorC
BED32_07495	COG1702	phosphate starvation-inducible protein PhoH
BED32_07500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BED32_07505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BED32_07540	COG0367	asparagine synthase
BED32_07545	COG0647	UMP catabolic process
BED32_07550	COG1940	carbohydrate kinase activity
BED32_07550	COG1846	Transcriptional regulator
BED32_07555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BED32_07560	COG0363	glucosamine-6-phosphate deaminase activity
BED32_07565	COG1263	PTS System
BED32_07565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_07565	COG2190	(PTS) system
BED32_07570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BED32_07590	COG0735	belongs to the Fur family
BED32_07600	COG0840	transmembrane signaling receptor activity
BED32_07610	COG0596	Alpha beta hydrolase
BED32_07615	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BED32_07620	COG0033	Phosphoglucomutase
BED32_07635	COG0745	RESPONSE REGULATOR receiver
BED32_07640	COG2205	protein histidine kinase activity
BED32_07645	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BED32_07650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BED32_07655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BED32_07675	COG2994	toxin metabolic process
BED32_07685	COG3272	Protein of unknown function (DUF1722)
BED32_07695	COG5212	phosphodiesterase
BED32_07700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BED32_07705	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BED32_07710	COG1984	allophanate hydrolase subunit 2
BED32_07715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BED32_07730	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BED32_07740	COG2009	succinate dehydrogenase
BED32_07745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BED32_07750	COG1053	succinate dehydrogenase
BED32_07760	COG0567	Dehydrogenase, E1 component
BED32_07765	COG0508	dehydrogenase complex catalyzes the overall conversion of
BED32_07770	COG0045	succinate-CoA ligase (ADP-forming) activity
BED32_07775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BED32_07780	COG0737	Belongs to the 5'-nucleotidase family
BED32_07785	COG1271	oxidase subunit
BED32_07790	COG1294	oxidase, subunit
BED32_07795	COG4890	Cyd operon protein YbgT
BED32_07800	COG3790	cyd operon protein YbgE
BED32_07805	COG0824	Thioesterase
BED32_07810	COG0811	peptide transport
BED32_07815	COG0848	biopolymer transport protein
BED32_07820	COG3064	Membrane
BED32_07820	COG3064	Membrane
BED32_07825	COG0823	Involved in the tonB-independent uptake of proteins
BED32_07830	COG2885	chlorophyll binding
BED32_07835	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BED32_07860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BED32_07870	COG1230	cation diffusion facilitator family transporter
BED32_07875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BED32_07880	COG0588	phosphoglycerate mutase activity
BED32_07905	COG2017	converts alpha-aldose to the beta-anomer
BED32_07910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BED32_07915	COG1085	galactose-1-phosphate uridylyltransferase
BED32_07920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BED32_07930	COG1119	ATPase activity
BED32_07935	COG3585	molybdate ion transport
BED32_07935	COG2005	Transcriptional regulator
BED32_07945	COG0725	ABC transporter, periplasmic molybdate-binding protein
BED32_07950	COG4149	molybdate abc transporter
BED32_07960	COG0561	phosphatase activity
BED32_07965	COG2706	6-phosphogluconolactonase activity
BED32_07975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BED32_07980	COG0156	8-amino-7-oxononanoate synthase activity
BED32_07985	COG2226	methyltransferase
BED32_07990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BED32_08000	COG0556	nucleotide-excision repair
BED32_08005	COG4628	conserved protein (DUF2132)
BED32_08010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BED32_08015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BED32_08020	COG0315	cyclic pyranopterin monophosphate synthase activity
BED32_08025	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BED32_08030	COG0314	molybdopterin synthase activity
BED32_08035	COG0670	Belongs to the BI1 family
BED32_08040	COG0842	Transport permease protein
BED32_08045	COG0842	Transport permease protein
BED32_08050	COG1131	(ABC) transporter
BED32_08055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_08060	COG1309	transcriptional regulator
BED32_08065	COG0513	Belongs to the DEAD box helicase family
BED32_08070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BED32_08080	COG2239	Acts as a magnesium transporter
BED32_08085	COG1686	Belongs to the peptidase S11 family
BED32_08090	COG0277	FAD linked oxidase domain protein
BED32_08100	COG1403	HNH endonuclease
BED32_08110	COG2261	transglycosylase associated protein
BED32_08120	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BED32_08135	COG4807	Protein conserved in bacteria
BED32_08155	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BED32_08165	COG2897	thiosulfate sulfurtransferase activity
BED32_08180	COG1732	Glycine betaine
BED32_08190	COG1125	glycine betaine transport
BED32_08195	COG1174	glycine betaine transport
BED32_08210	COG0583	DNA-binding transcription factor activity
BED32_08220	COG0697	spore germination
BED32_08240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BED32_08245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BED32_08265	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BED32_08275	COG1126	abc transporter atp-binding protein
BED32_08280	COG0765	amino acid transport
BED32_08285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BED32_08290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BED32_08295	COG0783	Belongs to the Dps family
BED32_08300	COG4106	trans-aconitate 2-methyltransferase activity
BED32_08315	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BED32_08335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BED32_08355	COG0488	(ABC) transporter
BED32_08365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BED32_08370	COG0303	'Molybdopterin
BED32_08385	COG1136	(ABC) transporter
BED32_08385	COG0577	efflux transmembrane transporter activity
BED32_08415	COG0583	DNA-binding transcription factor activity
BED32_08420	COG0477	Major facilitator Superfamily
BED32_08425	COG0302	gtp cyclohydrolase
BED32_08430	COG2311	Membrane
BED32_08455	COG3604	Transcriptional regulator
BED32_08465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BED32_08470	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BED32_08480	COG3260	NADH ubiquinone oxidoreductase 20
BED32_08485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BED32_08490	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BED32_08490	COG3261	NADH dehydrogenase
BED32_08495	COG0651	ATP synthesis coupled electron transport
BED32_08500	COG4237	Hydrogenase 4 membrane
BED32_08505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BED32_08510	COG0650	Formate hydrogenlyase subunit 4
BED32_08515	COG0651	ATP synthesis coupled electron transport
BED32_08520	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BED32_08525	COG0375	protein maturation
BED32_08530	COG0298	carbon dioxide binding
BED32_08535	COG2949	membrane
BED32_08540	COG0281	malic enzyme
BED32_08555	COG1346	cytolysis
BED32_08560	COG1380	Effector of murein hydrolase LrgA
BED32_08565	COG2814	Major facilitator Superfamily
BED32_08585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BED32_08585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BED32_08590	COG0489	protein tyrosine kinase activity
BED32_08595	COG0572	uridine kinase
BED32_08605	COG2982	Protein involved in outer membrane biogenesis
BED32_08610	COG3069	C4-dicarboxylate transmembrane transporter activity
BED32_08615	COG1253	flavin adenine dinucleotide binding
BED32_08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BED32_08675	COG3328	transposase activity
BED32_08700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BED32_08705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BED32_08710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BED32_08715	COG0140	phosphoribosyl-ATP diphosphatase activity
BED32_08715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BED32_08720	COG0107	imidazoleglycerol-phosphate synthase activity
BED32_08725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BED32_08730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BED32_08735	COG0131	Imidazoleglycerol-phosphate dehydratase
BED32_08735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BED32_08740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BED32_08750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BED32_08755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BED32_08760	COG1172	Belongs to the binding-protein-dependent transport system permease family
BED32_08765	COG1129	ABC transporter
BED32_08770	COG0371	Dehydrogenase
BED32_08780	COG0531	amino acid
BED32_08785	COG2925	Exonuclease
BED32_08790	COG1022	Amp-dependent synthetase and ligase
BED32_08790	COG3320	Male sterility
BED32_08795	COG1289	transmembrane transporter activity
BED32_08800	COG2926	Belongs to the UPF0265 family
BED32_08810	COG1172	Belongs to the binding-protein-dependent transport system permease family
BED32_08820	COG1879	ABC-type sugar transport system periplasmic component
BED32_08830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BED32_08840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BED32_08850	COG4810	utilization protein
BED32_08860	COG4656	Part of a membrane complex involved in electron transport
BED32_08870	COG1012	belongs to the aldehyde dehydrogenase family
BED32_08900	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BED32_08935	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BED32_08965	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BED32_08970	COG2241	protein methyltransferase activity
BED32_08980	COG2875	Belongs to the precorrin methyltransferase family
BED32_09030	COG1492	cobalamin metabolic process
BED32_09050	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BED32_09095	COG3501	Rhs element vgr protein
BED32_09120	COG0137	argininosuccinate synthase activity
BED32_09125	COG0534	Mate efflux family protein
BED32_09135	COG0352	thiamine-phosphate diphosphorylase activity
BED32_09140	COG0561	phosphatase activity
BED32_09145	COG1349	DNA-binding transcription factor activity
BED32_09155	COG0784	Response regulator, receiver
BED32_09155	COG0835	chemotaxis
BED32_09185	COG3842	ATPase activity
BED32_09195	COG1840	ABC-type Fe3 transport system, periplasmic component
BED32_09200	COG2271	Major facilitator Superfamily
BED32_09215	COG4565	transcriptional regulatory protein
BED32_09220	COG3290	protein histidine kinase activity
BED32_09235	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BED32_09240	COG3052	prosthetic group binding
BED32_09245	COG2301	Belongs to the HpcH HpaI aldolase family
BED32_09250	COG3051	citrate lyase alpha subunit
BED32_09255	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BED32_09255	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
BED32_09265	COG0471	metal ion transport
BED32_09280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BED32_09300	COG2814	Major facilitator Superfamily
BED32_09305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_09305	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_09310	COG3122	Protein conserved in bacteria
BED32_09330	COG3121	Chaperone
BED32_09370	COG3228	Belongs to the MtfA family
BED32_09380	COG1070	Carbohydrate kinase
BED32_09405	COG3121	Chaperone
BED32_09415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BED32_09445	COG0604	alcohol dehydrogenase
BED32_09445	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_09445	COG3321	synthase
BED32_09450	COG3328	transposase activity
BED32_09455	COG3250	beta-galactosidase activity
BED32_09460	COG1609	Transcriptional regulator
BED32_09465	COG1278	Cold shock
BED32_09475	COG0840	transmembrane signaling receptor activity
BED32_09490	COG1285	pathogenesis
BED32_09500	COG2130	NADP-dependent
BED32_09505	COG0589	response to stress
BED32_09530	COG0643	Histidine kinase
BED32_09530	COG2198	Histidine kinase
BED32_09535	COG0835	chemotaxis
BED32_09540	COG0840	transmembrane signaling receptor activity
BED32_09545	COG0840	transmembrane signaling receptor activity
BED32_09550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BED32_09560	COG0745	RESPONSE REGULATOR receiver
BED32_09565	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BED32_09575	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BED32_09580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BED32_09595	COG3418	PFAM FlgN family protein
BED32_09600	COG2747	anti-sigma28 factor FlgM
BED32_09615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BED32_09745	COG3772	lysozyme
BED32_09750	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BED32_09755	COG2979	Protein of unknown function (DUF533)
BED32_09770	COG0012	GTP binding
BED32_09780	COG0193	aminoacyl-tRNA hydrolase activity
BED32_09795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BED32_09805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BED32_09810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BED32_09815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BED32_09820	COG2890	protein-(glutamine-N5) methyltransferase activity
BED32_09825	COG3094	Invasion gene expression up-regulator, SirB
BED32_09830	COG2912	Transglutaminase-like superfamily
BED32_09835	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BED32_09840	COG0659	secondary active sulfate transmembrane transporter activity
BED32_09845	COG3706	GGDEF domain
BED32_09870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BED32_09875	COG3381	protein complex oligomerization
BED32_09885	COG0477	Major facilitator Superfamily
BED32_09900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BED32_09910	COG0673	inositol 2-dehydrogenase activity
BED32_09915	COG0728	peptidoglycan biosynthetic process
BED32_09920	COG0387	Pfam Sodium calcium exchanger
BED32_09930	COG2814	Major facilitator Superfamily
BED32_09945	COG3850	Histidine kinase
BED32_09950	COG1294	oxidase, subunit
BED32_09955	COG1271	oxidase subunit
BED32_09960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BED32_09970	COG3138	arginine N-succinyltransferase
BED32_09980	COG3724	N-succinylarginine dihydrolase activity
BED32_09985	COG2988	succinylglutamate desuccinylase activity
BED32_10015	COG1228	amidohydrolase
BED32_10025	COG0402	S-adenosylhomocysteine deaminase activity
BED32_10055	COG4942	peptidase
BED32_10065	COG2222	sugar isomerase
BED32_10070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_10075	COG3716	PTS system mannose fructose sorbose family IID component
BED32_10085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_10095	COG1349	DNA-binding transcription factor activity
BED32_10115	COG1187	pseudouridine synthase activity
BED32_10120	COG0786	glutamate:sodium symporter activity
BED32_10140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BED32_10145	COG2226	methyltransferase
BED32_10150	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BED32_10155	COG1801	Protein of unknown function DUF72
BED32_10160	COG1335	isochorismatase
BED32_10165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BED32_10170	COG0494	nUDIX hydrolase
BED32_10175	COG0217	transcriptional regulatory protein
BED32_10180	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BED32_10185	COG0632	four-way junction helicase activity
BED32_10190	COG2255	four-way junction helicase activity
BED32_10195	COG3104	oligopeptide transport
BED32_10200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BED32_10205	COG1121	(ABC) transporter
BED32_10210	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BED32_10215	COG0739	heme binding
BED32_10220	COG1560	Kdo2-lipid A biosynthetic process
BED32_10235	COG0469	pyruvate kinase activity
BED32_10240	COG1737	Transcriptional regulator
BED32_10245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BED32_10250	COG0800	Aldolase
BED32_10255	COG2076	Multidrug Resistance protein
BED32_10260	COG2076	Multidrug Resistance protein
BED32_10265	COG0251	oxidation-reduction process
BED32_10270	COG1199	ATP-dependent helicase activity
BED32_10285	COG0318	PFAM AMP-dependent synthetase and ligase
BED32_10290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BED32_10295	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BED32_10300	COG2894	cell division
BED32_10305	COG0850	regulation of cytokinetic process
BED32_10315	COG3100	YcgL domain-containing protein
BED32_10320	COG2951	lytic endotransglycosylase activity
BED32_10325	COG0179	Fumarylacetoacetate (FAA) hydrolase
BED32_10330	COG2983	Belongs to the UPF0260 family
BED32_10355	COG0668	transmembrane transport
BED32_10360	COG0625	glutathione transferase activity
BED32_10410	COG2814	Major facilitator Superfamily
BED32_10420	COG3008	intermembrane lipid transfer
BED32_10425	COG2995	paraquat-inducible protein a
BED32_10430	COG1956	GAF domain-containing protein
BED32_10440	COG0793	Belongs to the peptidase S41A family
BED32_10445	COG0501	Belongs to the peptidase M48B family
BED32_10460	COG0823	Involved in the tonB-independent uptake of proteins
BED32_10470	COG3023	N-Acetylmuramoyl-L-alanine amidase
BED32_10480	COG1988	membrane-bound metal-dependent
BED32_10490	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BED32_10495	COG1653	transport
BED32_10500	COG3842	ATPase activity
BED32_10505	COG0395	ABC-type sugar transport system, permease component
BED32_10510	COG1175	transmembrane transport
BED32_10520	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_10525	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BED32_10530	COG1917	Cupin 2, conserved barrel domain protein
BED32_10535	COG3328	transposase activity
BED32_10540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BED32_10550	COG0583	DNA-binding transcription factor activity
BED32_10555	COG0427	acetyl-CoA hydrolase
BED32_10560	COG1024	Enoyl-CoA hydratase
BED32_10565	COG1703	isobutyryl-CoA mutase activity
BED32_10580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BED32_10585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BED32_10590	COG1121	(ABC) transporter
BED32_10595	COG0803	Belongs to the bacterial solute-binding protein 9 family
BED32_10630	COG1811	Na channel or pump
BED32_10635	COG4249	Peptidase C14 caspase catalytic subunit p20
BED32_10640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BED32_10645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BED32_10650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BED32_10655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BED32_10660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BED32_10670	COG0776	regulation of translation
BED32_10685	COG4139	cobalamin transport
BED32_10690	COG0386	Belongs to the glutathione peroxidase family
BED32_10695	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BED32_10700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BED32_10705	COG0463	Glycosyl transferase, family 2
BED32_10710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BED32_10710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BED32_10715	COG0726	polysaccharide deacetylase
BED32_10720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BED32_10725	COG2076	Multidrug Resistance protein
BED32_10730	COG2076	Multidrug Resistance protein
BED32_10735	COG0791	NLP P60 protein
BED32_10775	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BED32_10780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BED32_10780	COG0574	Belongs to the PEP-utilizing enzyme family
BED32_10790	COG0628	permease
BED32_10795	COG0247	lactate metabolic process
BED32_10795	COG0277	FAD linked oxidase domain protein
BED32_10800	COG2050	protein possibly involved in aromatic compounds catabolism
BED32_10805	COG0316	Belongs to the HesB IscA family
BED32_10810	COG0719	Fe-S assembly protein
BED32_10815	COG0396	ATPase activity
BED32_10820	COG0719	Fe-S assembly protein
BED32_10830	COG2166	iron-sulfur cluster assembly
BED32_10835	COG1388	LysM domain
BED32_10835	COG1376	ErfK ybiS ycfS ynhG family protein
BED32_10840	COG4238	major outer membrane lipoprotein
BED32_10865	COG0307	riboflavin synthase, alpha
BED32_10870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BED32_10875	COG2814	Major facilitator Superfamily
BED32_10880	COG0583	DNA-binding transcription factor activity
BED32_10885	COG1609	Transcriptional regulator
BED32_10890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BED32_10895	COG0791	NLP P60 protein
BED32_10900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BED32_10905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BED32_10915	COG0346	lactoylglutathione lyase activity
BED32_10925	COG1309	transcriptional regulator
BED32_10930	COG2194	sulfuric ester hydrolase activity
BED32_10935	COG3313	Fe-S protein
BED32_10940	COG4989	oxidoreductase activity
BED32_10945	COG1289	transmembrane transporter activity
BED32_10960	COG1846	Transcriptional regulator
BED32_10965	COG3133	Outer membrane lipoprotein
BED32_10970	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BED32_10975	COG3895	Periplasmic Protein
BED32_10980	COG0259	pyridoxamine-phosphate oxidase activity
BED32_10995	COG0625	glutathione transferase activity
BED32_11020	COG3104	oligopeptide transport
BED32_11030	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BED32_11030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BED32_11040	COG4172	Belongs to the ABC transporter superfamily
BED32_11050	COG4171	peptide transport system, permease
BED32_11055	COG4168	peptide transport system, permease
BED32_11060	COG4166	transmembrane transport
BED32_11075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BED32_11080	COG1842	Phage shock protein A
BED32_11090	COG1983	PspC domain protein
BED32_11100	COG3106	COG3106 Predicted ATPase
BED32_11105	COG3768	UPF0283 membrane protein
BED32_11125	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BED32_11130	COG4948	Mandelate Racemase Muconate Lactonizing
BED32_11135	COG2866	Carboxypeptidase
BED32_11140	COG4166	transmembrane transport
BED32_11145	COG0598	Magnesium transport protein CorA
BED32_11150	COG0037	tRNA processing
BED32_11155	COG0823	Involved in the tonB-independent uptake of proteins
BED32_11170	COG1285	pathogenesis
BED32_11175	COG3042	response to heat
BED32_11180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BED32_11185	COG2911	Protein conserved in bacteria
BED32_11195	COG3784	Protein of unknown function (DUF1318)
BED32_11200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BED32_11205	COG1643	Atp-dependent helicase
BED32_11220	COG3591	Belongs to the peptidase S1B family
BED32_11230	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BED32_11235	COG2205	protein histidine kinase activity
BED32_11240	COG0745	RESPONSE REGULATOR receiver
BED32_11250	COG0531	amino acid
BED32_11265	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BED32_11270	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BED32_11275	COG0589	response to stress
BED32_11280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BED32_11285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BED32_11300	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BED32_11305	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_11330	COG1011	Hydrolase
BED32_11335	COG0440	acetolactate synthase activity
BED32_11340	COG0028	Belongs to the TPP enzyme family
BED32_11350	COG3023	N-Acetylmuramoyl-L-alanine amidase
BED32_11390	COG0583	DNA-binding transcription factor activity
BED32_11395	COG2814	Major facilitator Superfamily
BED32_11420	COG0114	fumarate hydratase activity
BED32_11430	COG5339	Protein conserved in bacteria
BED32_11440	COG1609	Transcriptional regulator
BED32_11445	COG1263	PTS System
BED32_11445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_11450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BED32_11455	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BED32_11460	COG0385	Bile acid
BED32_11465	COG0673	inositol 2-dehydrogenase activity
BED32_11485	COG1879	ABC-type sugar transport system periplasmic component
BED32_11495	COG2160	L-arabinose isomerase activity
BED32_11505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BED32_11535	COG4657	Part of a membrane complex involved in electron transport
BED32_11545	COG4656	Part of a membrane complex involved in electron transport
BED32_11555	COG3708	Transcriptional regulator
BED32_11555	COG2207	Transcriptional regulator
BED32_11560	COG4658	electron transport chain
BED32_11565	COG4659	FMN binding
BED32_11575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BED32_11650	COG0494	nUDIX hydrolase
BED32_11740	COG1484	DNA-dependent DNA replication
BED32_11820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BED32_11840	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BED32_11845	COG1966	Carbon starvation protein
BED32_11850	COG2879	small protein
BED32_11855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BED32_11860	COG1349	DNA-binding transcription factor activity
BED32_11870	COG0235	Class ii aldolase
BED32_11880	COG0023	Translation Initiation Factor
BED32_11885	COG0284	orotidine-5'-phosphate decarboxylase activity
BED32_11895	COG3135	benzoate transporter
BED32_11900	COG1396	sequence-specific DNA binding
BED32_11910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BED32_11915	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BED32_11920	COG0671	phosphoesterase, PA-phosphatase related
BED32_11925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BED32_11945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BED32_11955	COG0616	signal peptide processing
BED32_11960	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_11965	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BED32_11975	COG1187	pseudouridine synthase activity
BED32_11980	COG0009	L-threonylcarbamoyladenylate synthase
BED32_11985	COG0613	PHP domain protein
BED32_11995	COG0512	Glutamine amidotransferase of anthranilate synthase
BED32_12005	COG0135	phosphoribosylanthranilate isomerase activity
BED32_12005	COG0134	indole-3-glycerol-phosphate synthase activity
BED32_12010	COG0133	tryptophan synthase activity
BED32_12015	COG0159	tryptophan synthase activity
BED32_12025	COG3047	cAMP biosynthetic process
BED32_12045	COG2917	probably involved in intracellular septation
BED32_12050	COG1607	acyl-coa hydrolase
BED32_12055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BED32_12060	COG2350	Protein conserved in bacteria
BED32_12075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BED32_12080	COG3099	Belongs to the UPF0263 family
BED32_12090	COG0444	Belongs to the ABC transporter superfamily
BED32_12095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BED32_12115	COG2095	MarC family integral membrane protein
BED32_12120	COG1454	alcohol dehydrogenase
BED32_12120	COG1012	belongs to the aldehyde dehydrogenase family
BED32_12125	COG1435	thymidine kinase activity
BED32_12135	COG2916	Histone family protein nucleoid-structuring protein H-NS
BED32_12145	COG0745	RESPONSE REGULATOR receiver
BED32_12150	COG1752	Esterase of the alpha-beta hydrolase superfamily
BED32_12160	COG3012	SEC-C Motif Domain Protein
BED32_12165	COG0788	formyltetrahydrofolate deformylase activity
BED32_12180	COG0583	DNA-binding transcription factor activity
BED32_12185	COG0708	Exodeoxyribonuclease III
BED32_12190	COG0494	nUDIX hydrolase
BED32_12200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BED32_12210	COG0778	Nitroreductase
BED32_12215	COG0616	signal peptide processing
BED32_12220	COG0252	asparaginase activity
BED32_12225	COG1335	isochorismatase
BED32_12240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BED32_12255	COG3713	MltA-interacting MipA family protein
BED32_12260	COG2766	serine protein kinase
BED32_12265	COG2718	Belongs to the UPF0229 family
BED32_12280	COG0583	DNA-binding transcription factor activity
BED32_12290	COG2202	Pas domain
BED32_12290	COG2200	EAL domain
BED32_12290	COG2199	diguanylate cyclase activity
BED32_12300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BED32_12305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BED32_12310	COG2719	SpoVR family
BED32_12315	COG2186	Transcriptional regulator
BED32_12320	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BED32_12325	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BED32_12345	COG3142	Participates in the control of copper homeostasis
BED32_12350	COG3102	Protein conserved in bacteria
BED32_12355	COG0018	arginyl-trna synthetase
BED32_12365	COG1702	phosphate starvation-inducible protein PhoH
BED32_12380	COG3658	cytochrome
BED32_12385	COG1215	transferase activity, transferring glycosyl groups
BED32_12400	COG0006	proline dipeptidase activity
BED32_12410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BED32_12435	COG1136	(ABC) transporter
BED32_12435	COG0577	efflux transmembrane transporter activity
BED32_12445	COG0577	efflux transmembrane transporter activity
BED32_12445	COG1136	(ABC) transporter
BED32_12460	COG0672	)-iron permease
BED32_12475	COG2066	Belongs to the glutaminase family
BED32_12480	COG3622	Belongs to the hyi family
BED32_12485	COG0235	Class ii aldolase
BED32_12490	COG3395	kinase activity
BED32_12495	COG1349	DNA-binding transcription factor activity
BED32_12500	COG3290	protein histidine kinase activity
BED32_12505	COG4565	transcriptional regulatory protein
BED32_12510	COG3493	citrate carrier protein
BED32_12530	COG2223	nitrite transmembrane transporter activity
BED32_12535	COG0561	phosphatase activity
BED32_12545	COG3328	transposase activity
BED32_12550	COG0500	methyltransferase
BED32_12555	COG3328	transposase activity
BED32_12600	COG4974	Belongs to the 'phage' integrase family
BED32_12610	COG1276	copper resistance
BED32_12615	COG2372	response to copper ion
BED32_12620	COG1528	Iron-storage protein
BED32_12635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BED32_12640	COG1770	oligopeptidase
BED32_12655	COG3141	response to X-ray
BED32_12660	COG0513	Belongs to the DEAD box helicase family
BED32_12665	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BED32_12670	COG3140	Belongs to the UPF0181 family
BED32_12680	COG0494	nUDIX hydrolase
BED32_12685	COG1760	l-serine dehydratase
BED32_12695	COG1253	flavin adenine dinucleotide binding
BED32_12700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_12700	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_12705	COG3715	PTS system
BED32_12710	COG3716	PTS system mannose fructose sorbose family IID component
BED32_12715	COG4811	Protein of unknown function (DUF986)
BED32_12720	COG1971	Probably functions as a manganese efflux pump
BED32_12730	COG5002	protein histidine kinase activity
BED32_12730	COG5001	Diguanylate cyclase
BED32_12730	COG3447	MASE1 domain protein
BED32_12740	COG2226	methyltransferase
BED32_12745	COG0768	penicillin binding
BED32_12755	COG1278	Cold shock
BED32_12800	COG2207	Transcriptional regulator
BED32_12820	COG1132	(ABC) transporter
BED32_12840	COG4251	negative regulation of phosphorylation
BED32_12840	COG3706	GGDEF domain
BED32_12840	COG5001	Diguanylate cyclase
BED32_12840	COG2203	Gaf domain
BED32_12855	COG3755	Protein conserved in bacteria
BED32_12880	COG1733	regulation of RNA biosynthetic process
BED32_12885	COG0702	epimerase
BED32_12890	COG2873	o-acetylhomoserine
BED32_12910	COG0840	transmembrane signaling receptor activity
BED32_12930	COG2211	Major facilitator Superfamily
BED32_12945	COG0538	isocitrate dehydrogenase activity
BED32_12975	COG0538	isocitrate dehydrogenase activity
BED32_12980	COG1187	pseudouridine synthase activity
BED32_12990	COG0482	sulfurtransferase activity
BED32_12995	COG2915	High frequency lysogenization protein hflD homolog
BED32_13000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BED32_13010	COG0745	RESPONSE REGULATOR receiver
BED32_13030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BED32_13040	COG4591	ABC-type transport system involved in lipoprotein release permease component
BED32_13050	COG4591	ABC-type transport system involved in lipoprotein release permease component
BED32_13055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BED32_13060	COG3134	Outer membrane lipoprotein
BED32_13065	COG1252	NADH dehydrogenase
BED32_13070	COG3150	esterase
BED32_13075	COG1472	Belongs to the glycosyl hydrolase 3 family
BED32_13080	COG0510	thiamine kinase activity
BED32_13085	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BED32_13090	COG5633	Lipoprotein
BED32_13095	COG0537	adenosine 5'-monophosphoramidase activity
BED32_13100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BED32_13110	COG0641	radical SAM
BED32_13130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_13130	COG1263	PTS System
BED32_13135	COG0084	hydrolase, TatD family'
BED32_13140	COG0470	DNA polymerase III
BED32_13145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BED32_13150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BED32_13155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BED32_13160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BED32_13170	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_13175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BED32_13180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BED32_13185	COG0416	fatty acid biosynthetic process
BED32_13190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BED32_13195	COG1399	metal-binding, possibly nucleic acid-binding protein
BED32_13205	COG0564	pseudouridine synthase activity
BED32_13210	COG1530	ribonuclease E activity
BED32_13215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BED32_13220	COG0418	dihydroorotase activity
BED32_13245	COG0628	permease
BED32_13280	COG1560	Kdo2-lipid A biosynthetic process
BED32_13290	COG2259	Doxx family
BED32_13300	COG2814	Major facilitator Superfamily
BED32_13305	COG3104	oligopeptide transport
BED32_13310	COG2943	transferase activity, transferring hexosyl groups
BED32_13315	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BED32_13335	COG3263	regulation of cellular component size
BED32_13345	COG3916	Acyl-homoserine-lactone synthase
BED32_13350	COG2771	luxR family
BED32_13355	COG4235	cytochrome complex assembly
BED32_13365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BED32_13375	COG3301	Polysulphide reductase, NrfD
BED32_13380	COG0437	4 iron, 4 sulfur cluster binding
BED32_13385	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BED32_13400	COG2920	part of a sulfur-relay system
BED32_13405	COG1254	Belongs to the acylphosphatase family
BED32_13420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BED32_13425	COG3785	DNA binding
BED32_13430	COG1832	CoA-binding protein
BED32_13435	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BED32_13440	COG1803	Methylglyoxal synthase
BED32_13445	COG0210	DNA helicase
BED32_13450	COG3304	Inner membrane component domain
BED32_13455	COG1289	transmembrane transporter activity
BED32_13460	COG3070	regulator of competence-specific genes
BED32_13470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BED32_13470	COG2885	chlorophyll binding
BED32_13475	COG3120	sequence-specific DNA binding
BED32_13480	COG1067	ATP-dependent peptidase activity
BED32_13485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BED32_13495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BED32_13500	COG3009	Protein conserved in bacteria
BED32_13505	COG3008	intermembrane lipid transfer
BED32_13505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BED32_13510	COG2995	paraquat-inducible protein a
BED32_13515	COG0488	(ABC) transporter
BED32_13520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BED32_13520	COG0116	Belongs to the methyltransferase superfamily
BED32_13525	COG3217	Mosc domain protein beta barrel domain protein
BED32_13525	COG0633	Ferredoxin
BED32_13535	COG0167	dihydroorotate dehydrogenase activity
BED32_13540	COG0308	aminopeptidase N
BED32_13545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BED32_13550	COG0017	Asparaginyl-tRNA synthetase
BED32_13560	COG1448	Aminotransferase
BED32_13570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BED32_13575	COG3108	Peptidase M15
BED32_13580	COG2989	Protein conserved in bacteria
BED32_13585	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BED32_13590	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BED32_13595	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BED32_13600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BED32_13605	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BED32_13610	COG3173	Aminoglycoside phosphotransferase
BED32_13615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BED32_13620	COG2835	tetraacyldisaccharide 4'-kinase activity
BED32_13625	COG1278	Cold shock
BED32_13630	COG1278	Cold shock
BED32_13635	COG5383	Protein conserved in bacteria
BED32_13640	COG1663	tetraacyldisaccharide 4'-kinase activity
BED32_13650	COG2333	competence protein COMEC
BED32_13650	COG0658	competence protein
BED32_13655	COG0776	regulation of translation
BED32_13660	COG0539	negative regulation of cytoplasmic translation
BED32_13665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BED32_13670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BED32_13675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BED32_13680	COG2323	membrane
BED32_13685	COG0252	asparaginase activity
BED32_13690	COG1944	ATP diphosphatase activity
BED32_13695	COG2116	formate transmembrane transporter activity
BED32_13700	COG1882	Formate acetyltransferase
BED32_13705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BED32_13710	COG2814	Major facilitator Superfamily
BED32_13715	COG3328	transposase activity
BED32_13725	COG3547	Transposase (IS116 IS110 IS902 family)
BED32_13730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BED32_13735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BED32_13740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BED32_13745	COG3107	peptidoglycan biosynthetic process
BED32_13745	COG1674	ftsk spoiiie
BED32_13750	COG1522	sequence-specific DNA binding
BED32_13755	COG0492	ferredoxin-NADP+ reductase activity
BED32_13765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BED32_13770	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BED32_13775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BED32_13780	COG0542	response to heat
BED32_13785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BED32_13790	COG1278	Cold shock
BED32_13800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_13805	COG2990	Protein conserved in bacteria
BED32_13810	COG3593	DNA synthesis involved in DNA repair
BED32_13815	COG2431	L-lysine efflux transmembrane transporter activity
BED32_13820	COG1151	hydroxylamine reductase activity
BED32_13825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BED32_13830	COG0028	Belongs to the TPP enzyme family
BED32_13840	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BED32_13845	COG0702	epimerase
BED32_13850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BED32_13860	COG1126	abc transporter atp-binding protein
BED32_13865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BED32_13870	COG4215	(ABC) transporter
BED32_13875	COG4160	amino acid transport
BED32_13880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BED32_13885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BED32_13895	COG1177	transmembrane transport
BED32_13900	COG1176	ABC-type spermidine putrescine transport system, permease component I
BED32_13905	COG3842	ATPase activity
BED32_13910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BED32_13925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BED32_13930	COG0569	domain protein
BED32_13930	COG2985	domain, Protein
BED32_13940	COG0671	phosphoesterase, PA-phosphatase related
BED32_13945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BED32_13950	COG1349	DNA-binding transcription factor activity
BED32_13955	COG0814	amino acid
BED32_13960	COG1760	l-serine dehydratase
BED32_13970	COG1686	Belongs to the peptidase S11 family
BED32_13980	COG0626	cystathionine gamma-synthase activity
BED32_13985	COG2011	ABC-type metal ion transport system permease component
BED32_14010	COG0625	glutathione transferase activity
BED32_14015	COG4771	TonB-dependent receptor
BED32_14025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BED32_14030	COG0833	amino acid
BED32_14035	COG0583	DNA-binding transcription factor activity
BED32_14050	COG2855	membrane
BED32_14055	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BED32_14080	COG3710	Transcriptional regulator
BED32_14085	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BED32_14085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BED32_14085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BED32_14090	COG1105	Belongs to the carbohydrate kinase PfkB family
BED32_14105	COG3005	denitrification pathway
BED32_14110	COG0243	molybdopterin cofactor binding
BED32_14125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BED32_14130	COG1312	Catalyzes the dehydration of D-mannonate
BED32_14140	COG0246	Mannitol dehydrogenase
BED32_14145	COG2186	Transcriptional regulator
BED32_14155	COG0523	cobalamin synthesis protein
BED32_14160	COG0671	phosphoesterase, PA-phosphatase related
BED32_14165	COG0791	NLP P60 protein
BED32_14175	COG2200	EAL domain
BED32_14180	COG4166	transmembrane transport
BED32_14185	COG4174	ABC transporter (Permease)
BED32_14190	COG4239	(ABC) transporter, permease
BED32_14195	COG4172	Belongs to the ABC transporter superfamily
BED32_14205	COG2814	Major facilitator Superfamily
BED32_14210	COG1187	pseudouridine synthase activity
BED32_14215	COG1061	Type III restriction enzyme res subunit
BED32_14220	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BED32_14225	COG3081	Nucleoid-associated protein
BED32_14230	COG3082	Protein of unknown function (DUF1414)
BED32_14255	COG3328	transposase activity
BED32_14270	COG2801	Transposase and inactivated derivatives
BED32_14285	COG3338	carbonate dehydratase activity
BED32_14290	COG2723	6-phospho-beta-galactosidase activity
BED32_14295	COG1263	PTS System
BED32_14295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_14295	COG2190	(PTS) system
BED32_14300	COG1737	Transcriptional regulator
BED32_14355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BED32_14370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BED32_14385	COG2223	nitrite transmembrane transporter activity
BED32_14390	COG2198	Histidine kinase
BED32_14390	COG0642	Histidine kinase
BED32_14395	COG2197	response regulator
BED32_14400	COG2205	protein histidine kinase activity
BED32_14400	COG0784	Response regulator, receiver
BED32_14410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BED32_14415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BED32_14430	COG4574	serine-type endopeptidase inhibitor activity
BED32_14450	COG0814	amino acid
BED32_14470	COG1441	menaquinone biosynthetic process
BED32_14475	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BED32_14480	COG0596	Alpha beta hydrolase
BED32_14485	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BED32_14490	COG1169	isochorismate synthase
BED32_14495	COG4575	ribosome binding
BED32_14500	COG0129	dihydroxy-acid dehydratase activity
BED32_14505	COG4702	Belongs to the UPF0303 family
BED32_14515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BED32_14520	COG1609	Transcriptional regulator
BED32_14525	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_14530	COG3265	gluconokinase activity
BED32_14550	COG1007	ATP synthesis coupled electron transport
BED32_14555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BED32_14560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BED32_14565	COG0713	ATP synthesis coupled electron transport
BED32_14570	COG0839	Belongs to the complex I subunit 6 family
BED32_14575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BED32_14580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BED32_14585	COG1034	ATP synthesis coupled electron transport
BED32_14595	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BED32_14600	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BED32_14600	COG0649	NAD binding
BED32_14605	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BED32_14610	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BED32_14615	COG0583	DNA-binding transcription factor activity
BED32_14620	COG0436	Aminotransferase
BED32_14625	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BED32_14630	COG0490	domain, Protein
BED32_14630	COG0471	metal ion transport
BED32_14640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BED32_14645	COG3013	Belongs to the UPF0304 family
BED32_14650	COG3092	negative regulation of chromosome organization
BED32_14660	COG0857	belongs to the CobB CobQ family
BED32_14660	COG0280	phosphate acetyltransferase
BED32_14665	COG1609	Transcriptional regulator
BED32_14670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_14680	COG3037	sugar-specific permease SgaT UlaA
BED32_14690	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BED32_14705	COG1090	epimerase
BED32_14715	COG4598	ABC transporter
BED32_14720	COG4160	amino acid transport
BED32_14725	COG4215	(ABC) transporter
BED32_14730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BED32_14735	COG0163	prenyltransferase activity
BED32_14740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BED32_14745	COG1286	toxin biosynthetic process
BED32_14750	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BED32_14755	COG0285	dihydrofolate synthase activity
BED32_14760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BED32_14765	COG0586	Pfam SNARE associated Golgi protein
BED32_14775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BED32_14780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BED32_14795	COG0697	spore germination
BED32_14800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BED32_14805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BED32_14830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BED32_14840	COG1609	Transcriptional regulator
BED32_14850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BED32_14855	COG2723	6-phospho-beta-galactosidase activity
BED32_14860	COG1447	Phosphotransferase system cellobiose-specific component IIA
BED32_14870	COG1794	racemase activity, acting on amino acids and derivatives
BED32_14880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BED32_14885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BED32_14885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BED32_14895	COG3101	peptidyl-lysine hydroxylation
BED32_14900	COG0730	response to heat
BED32_14905	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BED32_14910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BED32_14915	COG2890	protein-(glutamine-N5) methyltransferase activity
BED32_14920	COG2840	Smr protein MutS2
BED32_14925	COG2062	phosphohistidine phosphatase, SixA
BED32_14930	COG1250	3-hydroxyacyl-CoA dehydrogenase
BED32_14930	COG1024	Enoyl-CoA hydratase
BED32_14935	COG0183	Belongs to the thiolase family
BED32_14940	COG3691	Protein conserved in bacteria
BED32_14955	COG4235	cytochrome complex assembly
BED32_14955	COG3088	subunit of a heme lyase
BED32_14965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BED32_14970	COG1138	Cytochrome C-type biogenesis protein
BED32_14975	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BED32_14980	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BED32_14985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BED32_14990	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BED32_15005	COG2116	formate transmembrane transporter activity
BED32_15015	COG0582	viral genome integration into host DNA
BED32_15075	COG2824	Alkylphosphonate utilization operon protein PhnA
BED32_15080	COG1695	Transcriptional regulator
BED32_15090	COG2723	6-phospho-beta-galactosidase activity
BED32_15095	COG1263	PTS System
BED32_15095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BED32_15100	COG1609	Transcriptional regulator
BED32_15105	COG2353	YceI-like domain
BED32_15110	COG3038	cytochrome b561
BED32_15115	COG2755	lipolytic protein G-D-S-L family
BED32_15115	COG0657	acetylesterase activity
BED32_15135	COG1127	ABC transporter
BED32_15140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BED32_15160	COG0531	amino acid
BED32_15165	COG2951	lytic endotransglycosylase activity
BED32_15195	COG1598	PFAM Uncharacterised protein family UPF0150
BED32_15200	COG3038	cytochrome b561
BED32_15205	COG0436	Aminotransferase
BED32_15225	COG3279	Response regulator of the LytR AlgR family
BED32_15235	COG0837	glucose binding
BED32_15250	COG3961	Belongs to the TPP enzyme family
BED32_15255	COG0667	Aldo Keto reductase
BED32_15265	COG1914	H( )-stimulated, divalent metal cation uptake system
BED32_15270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BED32_15300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BED32_15325	COG3530	Putative quorum-sensing-regulated virulence factor
BED32_15330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BED32_15345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BED32_15350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_15355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BED32_15360	COG2190	(PTS) system
BED32_15365	COG2205	protein histidine kinase activity
BED32_15370	COG0745	RESPONSE REGULATOR receiver
BED32_15375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_15395	COG4208	sulfate ABC transporter
BED32_15400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BED32_15405	COG4150	thiosulfate binding
BED32_15415	COG1737	Transcriptional regulator
BED32_15420	COG2731	YhcH YjgK YiaL family protein
BED32_15435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BED32_15445	COG2837	iron assimilation
BED32_15455	COG3111	PFAM Bacterial OB fold (BOF) protein
BED32_15460	COG0456	acetyltransferase
BED32_15465	COG0408	coproporphyrinogen oxidase activity
BED32_15470	COG1671	Belongs to the UPF0178 family
BED32_15485	COG0494	nUDIX hydrolase
BED32_15495	COG3043	anaerobic respiration
BED32_15500	COG0243	molybdopterin cofactor binding
BED32_15505	COG3062	negative regulation of establishment of protein localization
BED32_15515	COG2197	response regulator
BED32_15525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BED32_15545	COG1393	Belongs to the ArsC family
BED32_15550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BED32_15555	COG1876	peptidase activity
BED32_15600	COG0400	carboxylic ester hydrolase activity
BED32_15615	COG1444	tRNA N-acetyltransferase activity
BED32_15620	COG2707	UPF0756 membrane protein
BED32_15625	COG2321	neutral zinc metallopeptidase
BED32_15630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BED32_15635	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BED32_15640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BED32_15645	COG2716	regulation of RNA biosynthetic process
BED32_15650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BED32_15655	COG0628	permease
BED32_15660	COG4783	chaperone-mediated protein folding
BED32_15665	COG1393	Belongs to the ArsC family
BED32_15670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BED32_15675	COG2233	PERMEase
BED32_15680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BED32_15690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BED32_15695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BED32_15710	COG0581	inorganic phosphate transmembrane transporter activity
BED32_15715	COG0573	inorganic phosphate transmembrane transporter activity
BED32_15720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BED32_15725	COG0248	Ppx GppA phosphatase
BED32_15740	COG5001	Diguanylate cyclase
BED32_15740	COG5002	protein histidine kinase activity
BED32_15740	COG3447	MASE1 domain protein
BED32_15745	COG0443	Heat shock 70 kDa protein
BED32_15750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_15760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BED32_15765	COG0477	Major facilitator Superfamily
BED32_15770	COG2205	protein histidine kinase activity
BED32_15775	COG0745	RESPONSE REGULATOR receiver
BED32_15780	COG3422	double-strand break repair
BED32_15795	COG3730	PTS system glucitol sorbitol-specific
BED32_15810	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_15815	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_15820	COG1349	DNA-binding transcription factor activity
BED32_15840	COG0351	phosphomethylpyrimidine kinase
BED32_15865	COG3328	transposase activity
BED32_15930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BED32_15930	COG0519	Catalyzes the synthesis of GMP from XMP
BED32_15935	COG0517	IMP dehydrogenase activity
BED32_15935	COG0516	GMP reductase activity
BED32_15940	COG1570	exodeoxyribonuclease VII activity
BED32_15945	COG1645	bacterial-type flagellum-dependent swarming motility
BED32_15960	COG1160	GTP binding
BED32_15970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BED32_15980	COG0124	histidyl-tRNA synthetase
BED32_15985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BED32_15990	COG1426	Protein conserved in bacteria
BED32_16000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BED32_16015	COG4953	penicillin-binding protein 1C
BED32_16020	COG2373	Large extracellular alpha-helical protein
BED32_16025	COG3468	outer membrane autotransporter barrel domain protein
BED32_16040	COG2975	iron-sulfur cluster assembly
BED32_16045	COG0633	Ferredoxin
BED32_16050	COG0443	Heat shock 70 kDa protein
BED32_16055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BED32_16060	COG0316	Belongs to the HesB IscA family
BED32_16065	COG0822	iron-sulfur transferase activity
BED32_16075	COG1959	2 iron, 2 sulfur cluster binding
BED32_16080	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BED32_16085	COG0483	inositol monophosphate 1-phosphatase activity
BED32_16090	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BED32_16095	COG3683	transport system, periplasmic component
BED32_16105	COG2814	Major facilitator Superfamily
BED32_16110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BED32_16115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BED32_16115	COG1017	nitric oxide dioxygenase activity
BED32_16120	COG2188	Transcriptional regulator
BED32_16130	COG3457	Alanine racemase
BED32_16135	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BED32_16150	COG0347	Belongs to the P(II) protein family
BED32_16155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BED32_16155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BED32_16160	COG2204	response regulator
BED32_16165	COG3170	Tfp pilus assembly protein FimV
BED32_16170	COG2205	protein histidine kinase activity
BED32_16185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BED32_16190	COG0590	tRNA wobble adenosine to inosine editing
BED32_16200	COG0560	Phosphoserine phosphatase
BED32_16210	COG1737	Transcriptional regulator
BED32_16215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BED32_16225	COG0736	holo-[acyl-carrier-protein] synthase activity
BED32_16230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BED32_16235	COG1381	Involved in DNA repair and RecF pathway recombination
BED32_16240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BED32_16245	COG0571	ribonuclease III activity
BED32_16250	COG0681	Belongs to the peptidase S26 family
BED32_16255	COG0481	GTPase activity
BED32_16265	COG3086	response to oxidative stress
BED32_16270	COG3026	antisigma factor binding
BED32_16275	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BED32_16285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BED32_16290	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BED32_16295	COG0513	Belongs to the DEAD box helicase family
BED32_16325	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
BED32_16330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BED32_16335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BED32_16340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BED32_16345	COG0497	DNA recombination
BED32_16350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BED32_16360	COG2867	negative regulation of translational initiation
BED32_16365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BED32_16380	COG0659	secondary active sulfate transmembrane transporter activity
BED32_16385	COG3394	polysaccharide catabolic process
BED32_16390	COG1917	Cupin 2, conserved barrel domain protein
BED32_16390	COG2169	Transcriptional regulator
BED32_16395	COG1447	Phosphotransferase system cellobiose-specific component IIA
BED32_16400	COG2723	6-phospho-beta-galactosidase activity
BED32_16405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BED32_16410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BED32_16425	COG0667	Aldo Keto reductase
BED32_16435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BED32_16440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BED32_16450	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BED32_16455	COG4413	Urea transporter
BED32_16460	COG0829	nickel cation binding
BED32_16465	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BED32_16470	COG0830	nickel cation binding
BED32_16480	COG0804	urea catabolic process
BED32_16485	COG0832	Belongs to the urease beta subunit family
BED32_16495	COG1124	(ABC) transporter
BED32_16505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BED32_16545	COG1278	Cold shock
BED32_16565	COG0477	Major facilitator Superfamily
BED32_16570	COG2207	Transcriptional regulator
BED32_16585	COG4575	ribosome binding
BED32_16595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BED32_16605	COG1780	Probably involved in ribonucleotide reductase function
BED32_16615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BED32_16625	COG4176	ABC-type proline glycine betaine transport system permease component
BED32_16630	COG2113	Glycine betaine
BED32_16640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BED32_16645	COG0328	RNA-DNA hybrid ribonuclease activity
BED32_16650	COG2226	methyltransferase
BED32_16655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BED32_16660	COG1388	LysM domain
BED32_16660	COG0741	lytic transglycosylase activity
BED32_16670	COG3021	interspecies interaction between organisms
BED32_16675	COG2814	Major facilitator Superfamily
BED32_16680	COG0583	DNA-binding transcription factor activity
BED32_16685	COG0656	L-ascorbic acid biosynthetic process
BED32_16695	COG3328	transposase activity
BED32_16740	COG2011	ABC-type metal ion transport system permease component
BED32_16745	COG1464	Belongs to the NlpA lipoprotein family
BED32_16755	COG1720	tRNA m6t6A37 methyltransferase activity
BED32_16760	COG0442	prolyl-tRNA aminoacylation
BED32_16765	COG3015	lipoprotein NlpE involved in copper resistance
BED32_16775	COG4681	YaeQ
BED32_16785	COG4568	rho-dependent transcription termination
BED32_16795	COG0037	tRNA processing
BED32_16800	COG0346	lactoylglutathione lyase activity
BED32_16810	COG0825	malonyl-CoA metabolic process
BED32_16820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BED32_16825	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BED32_16835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BED32_16840	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BED32_16845	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BED32_16855	COG0750	zinc metalloprotease
BED32_16860	COG0575	Belongs to the CDS family
BED32_16865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BED32_16870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BED32_16875	COG0233	cytoplasmic translational termination
BED32_16880	COG0528	UMP kinase activity
BED32_16885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BED32_16890	COG0052	Belongs to the universal ribosomal protein uS2 family
BED32_16900	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BED32_16905	COG2171	N-acyltransferase activity
BED32_16920	COG0564	pseudouridine synthase activity
BED32_16925	COG3098	single-species biofilm formation
BED32_16935	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BED32_16935	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BED32_16940	COG1611	Belongs to the LOG family
BED32_16945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BED32_16955	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BED32_16960	COG2363	Small membrane protein
BED32_16965	COG0583	DNA-binding transcription factor activity
BED32_16975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BED32_16980	COG2166	iron-sulfur cluster assembly
BED32_16985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BED32_16990	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BED32_17010	COG0860	N-Acetylmuramoyl-L-alanine amidase
BED32_17015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BED32_17015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BED32_17020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BED32_17025	COG1074	ATP-dependent DNA helicase activity
BED32_17030	COG1025	Belongs to the peptidase M16 family
BED32_17035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BED32_17040	COG4967	type IV pilus modification protein PilV
BED32_17060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BED32_17065	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BED32_17085	COG3066	DNA modification
BED32_17090	COG0861	Integral membrane protein TerC family
BED32_17095	COG0667	Aldo Keto reductase
BED32_17105	COG0318	PFAM AMP-dependent synthetase and ligase
BED32_17105	COG0204	Acyl-transferase
BED32_17115	COG1609	Transcriptional regulator
BED32_17120	COG0019	diaminopimelate decarboxylase activity
BED32_17125	COG0583	DNA-binding transcription factor activity
BED32_17130	COG2814	Major facilitator Superfamily
BED32_17200	COG2165	general secretion pathway protein
BED32_17230	COG0288	reversible hydration of carbon dioxide
BED32_17235	COG1733	regulation of RNA biosynthetic process
BED32_17240	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_17250	COG0484	heat shock protein binding
BED32_17260	COG3706	GGDEF domain
BED32_17265	COG4319	ketosteroid isomerase
BED32_17280	COG3328	transposase activity
BED32_17285	COG2944	sequence-specific DNA binding
BED32_17385	COG0582	viral genome integration into host DNA
BED32_17395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BED32_17400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BED32_17405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BED32_17410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BED32_17415	COG4974	Belongs to the 'phage' integrase family
BED32_17420	COG0716	FMN binding
BED32_17425	COG4452	Inner membrane protein CreD
BED32_17430	COG2205	protein histidine kinase activity
BED32_17435	COG0745	RESPONSE REGULATOR receiver
BED32_17445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BED32_17450	COG0354	folic acid binding
BED32_17460	COG1272	protein, Hemolysin III
BED32_17470	COG1028	Short-chain dehydrogenase reductase Sdr
BED32_17480	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BED32_17480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BED32_17485	COG0509	glycine decarboxylation via glycine cleavage system
BED32_17490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BED32_17495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BED32_17500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BED32_17505	COG0006	proline dipeptidase activity
BED32_17510	COG3079	Belongs to the UPF0149 family
BED32_17515	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BED32_17525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BED32_17530	COG0148	phosphopyruvate hydratase activity
BED32_17535	COG0504	CTP synthase activity
BED32_17540	COG3956	TIGRFAM MazG family protein
BED32_17545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BED32_17550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BED32_17555	COG2205	protein histidine kinase activity
BED32_17555	COG4999	Histidine kinase
BED32_17555	COG3850	Histidine kinase
BED32_17555	COG3437	response regulator, receiver
BED32_17560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BED32_17565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BED32_17570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BED32_17580	COG2860	membrane
BED32_17585	COG0316	Belongs to the HesB IscA family
BED32_17595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BED32_17600	COG2223	nitrite transmembrane transporter activity
BED32_17605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BED32_17610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BED32_17615	COG1120	ATPase activity
BED32_17620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BED32_17625	COG1643	Atp-dependent helicase
BED32_17630	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BED32_17635	COG1489	DNA binding
BED32_17640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BED32_17655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BED32_17660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BED32_17665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BED32_17670	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BED32_17675	COG0726	polysaccharide deacetylase
BED32_17680	COG0842	Transport permease protein
BED32_17685	COG1131	(ABC) transporter
BED32_17690	COG0288	reversible hydration of carbon dioxide
BED32_17700	COG2132	Multicopper oxidase
BED32_17710	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BED32_17715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BED32_17725	COG0697	spore germination
BED32_17730	COG3112	Uncharacterised protein family (UPF0231)
BED32_17745	COG4977	sequence-specific DNA binding
BED32_17755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BED32_17760	COG0508	dehydrogenase complex catalyzes the overall conversion of
BED32_17765	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BED32_17770	COG2186	Transcriptional regulator
BED32_17775	COG1113	amino acid transport
BED32_17780	COG3725	Membrane protein required for beta-lactamase induction
BED32_17795	COG4969	Belongs to the N-Me-Phe pilin family
BED32_17800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BED32_17805	COG1459	type II secretion system
BED32_17810	COG0516	GMP reductase activity
BED32_17815	COG0237	dephospho-CoA kinase activity
BED32_17825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BED32_17830	COG0494	nUDIX hydrolase
BED32_17835	COG0653	protein targeting
BED32_17855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BED32_17860	COG0849	cell division
BED32_17865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BED32_17875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BED32_17880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BED32_17885	COG0772	Belongs to the SEDS family
BED32_17895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BED32_17900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BED32_17905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BED32_17910	COG0768	penicillin binding
BED32_17920	COG0275	rRNA processing
BED32_17925	COG2001	Belongs to the MraZ family
BED32_17935	COG1609	Transcriptional regulator
BED32_17945	COG0028	Belongs to the TPP enzyme family
BED32_17950	COG1022	Amp-dependent synthetase and ligase
BED32_17960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BED32_17965	COG0473	3-isopropylmalate dehydrogenase activity
BED32_17970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BED32_17990	COG2814	Major facilitator Superfamily
BED32_18005	COG4533	DNA binding
BED32_18020	COG4143	(ABC) transporter
BED32_18025	COG1178	ABC-type Fe3 transport system permease component
BED32_18035	COG0586	Pfam SNARE associated Golgi protein
BED32_18040	COG0417	DNA replication proofreading
BED32_18045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BED32_18055	COG0564	pseudouridine synthase activity
BED32_18060	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BED32_18065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BED32_18070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BED32_18080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BED32_18085	COG2967	ApaG domain
BED32_18090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BED32_18095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BED32_18100	COG3610	response to peptide
BED32_18105	COG2966	Psort location CytoplasmicMembrane, score
BED32_18110	COG1280	lysine exporter protein (LysE YggA)
BED32_18115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BED32_18120	COG0505	Belongs to the CarA family
BED32_18125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BED32_18130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BED32_18135	COG1047	Peptidyl-prolyl cis-trans
BED32_18140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BED32_18145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BED32_18150	COG0196	riboflavin kinase activity
BED32_18160	COG0268	Binds directly to 16S ribosomal RNA
BED32_18165	COG0583	DNA-binding transcription factor activity
BED32_18170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BED32_18175	COG0484	heat shock protein binding
BED32_18180	COG0443	Heat shock 70 kDa protein
BED32_18185	COG1584	GPR1 FUN34 yaaH family protein
BED32_18200	COG0521	Mo-molybdopterin cofactor biosynthetic process
BED32_18205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BED32_18210	COG3022	response to hydroperoxide
BED32_18225	COG0083	homoserine kinase activity
BED32_18240	COG0745	RESPONSE REGULATOR receiver
BED32_18245	COG3045	CreA protein
BED32_18250	COG2207	Transcriptional regulator
BED32_18250	COG3708	Transcriptional regulator
BED32_18255	COG0406	alpha-ribazole phosphatase activity
BED32_18265	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BED32_18270	COG0741	lytic transglycosylase activity
BED32_18275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BED32_18285	COG2199	diguanylate cyclase activity
BED32_18290	COG2885	chlorophyll binding
BED32_18295	COG0488	(ABC) transporter
BED32_18310	COG0604	alcohol dehydrogenase
BED32_18325	COG0560	Phosphoserine phosphatase
BED32_18330	COG3726	membrane protein affecting hemolysin expression
BED32_18335	COG0813	purine-nucleoside phosphorylase activity
BED32_18340	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BED32_18345	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BED32_18350	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BED32_18355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BED32_18360	COG0084	hydrolase, TatD family'
BED32_18365	COG4667	esterase of the alpha-beta hydrolase superfamily
BED32_18375	COG2823	Periplasmic or secreted lipoprotein
BED32_18380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BED32_18385	COG0456	acetyltransferase
BED32_18390	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BED32_18395	COG2813	Specifically methylates the guanine in position
BED32_18400	COG0667	Aldo Keto reductase
BED32_18420	COG3706	GGDEF domain
BED32_18425	COG4772	TonB-dependent receptor
BED32_18460	COG3284	Transcriptional regulator
BED32_18495	COG2192	nodulation
BED32_18510	COG1461	Dihydroxyacetone kinase
BED32_18515	COG2376	Dihydroxyacetone kinase
BED32_18525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BED32_18530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BED32_18535	COG2235	arginine
BED32_18550	COG0859	PFAM glycosyl transferase family 9
BED32_18555	COG1070	Carbohydrate kinase
BED32_18560	COG2390	Transcriptional regulator
BED32_18565	COG1129	ABC transporter
BED32_18570	COG1172	Belongs to the binding-protein-dependent transport system permease family
BED32_18575	COG1172	Belongs to the binding-protein-dependent transport system permease family
BED32_18580	COG1879	ABC-type sugar transport system periplasmic component
BED32_18585	COG1830	Aldolase
BED32_18590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BED32_18605	COG3328	transposase activity
BED32_18635	COG0795	lipopolysaccharide-transporting ATPase activity
BED32_18640	COG0795	lipopolysaccharide-transporting ATPase activity
BED32_18645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BED32_18650	COG2927	DNA polymerase III (CHI subunit)
BED32_18665	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BED32_18675	COG2731	YhcH YjgK YiaL family protein
BED32_18685	COG0601	transmembrane transport
BED32_18695	COG0444	Belongs to the ABC transporter superfamily
BED32_18700	COG4608	Belongs to the ABC transporter superfamily
BED32_18730	COG2188	Transcriptional regulator
BED32_18735	COG3624	Phosphonate C-P lyase system protein PhnG
BED32_18740	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BED32_18745	COG3626	phosphonate metabolism
BED32_18750	COG3627	carbon phosphorus lyase activity
BED32_18755	COG4107	phosphonate C-P lyase system protein PhnK
BED32_18760	COG4778	phosphonate C-P lyase system protein PhnL
BED32_18765	COG3454	Phosphonate metabolism
BED32_18775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BED32_18780	COG0702	epimerase
BED32_18795	COG3787	Belongs to the UPF0306 family
BED32_18805	COG3842	ATPase activity
BED32_18810	COG0395	ABC-type sugar transport system, permease component
BED32_18820	COG1653	transport
BED32_18835	COG1982	Orn Lys Arg decarboxylase major
BED32_18840	COG0531	amino acid
BED32_18850	COG3153	acetyltransferase
BED32_18870	COG3681	Belongs to the UPF0597 family
BED32_18875	COG0814	amino acid
BED32_18885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BED32_18895	COG0513	Belongs to the DEAD box helicase family
BED32_18905	COG1185	polyribonucleotide nucleotidyltransferase activity
BED32_18910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BED32_18915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BED32_18920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BED32_18925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BED32_18930	COG0195	Participates in both transcription termination and antitermination
BED32_18935	COG0779	Required for maturation of 30S ribosomal subunits
BED32_18950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BED32_18955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BED32_18960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BED32_18965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BED32_18970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BED32_18975	COG1534	Rna-binding protein
BED32_18980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BED32_18985	COG2027	D-alanyl-D-alanine carboxypeptidase
BED32_18990	COG0745	RESPONSE REGULATOR receiver
BED32_18995	COG0642	Histidine kinase
BED32_19000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BED32_19005	COG0697	spore germination
BED32_19010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BED32_19015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BED32_19020	COG0142	geranyltranstransferase activity
BED32_19030	COG3423	Transcriptional regulator
BED32_19035	COG0039	L-malate dehydrogenase activity
BED32_19040	COG1438	arginine binding
BED32_19050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BED32_19055	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BED32_19065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BED32_19070	COG2105	PFAM AIG2 family protein
BED32_19085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BED32_19090	COG1253	flavin adenine dinucleotide binding
BED32_19100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BED32_19105	COG1218	3'(2'),5'-bisphosphate nucleotidase
BED32_19110	COG0737	Belongs to the 5'-nucleotidase family
BED32_19120	COG0545	Peptidyl-prolyl cis-trans isomerase
BED32_19125	COG3061	Opacity-associated protein A
BED32_19135	COG0359	binds to the 23S rRNA
BED32_19140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BED32_19145	COG2965	DNA replication, synthesis of RNA primer
BED32_19150	COG0360	Binds together with S18 to 16S ribosomal RNA
BED32_19160	COG1073	alpha beta
BED32_19165	COG3650	response to hydrogen peroxide
BED32_19170	COG1960	acyl-CoA dehydrogenase activity
BED32_19180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BED32_19185	COG0557	exoribonuclease II activity
BED32_19190	COG1959	2 iron, 2 sulfur cluster binding
BED32_19195	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BED32_19200	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BED32_19205	COG0330	HflC and HflK could
BED32_19210	COG0330	HflC and HflK could
BED32_19215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BED32_19220	COG1923	regulation of RNA biosynthetic process
BED32_19225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BED32_19230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BED32_19235	COG0860	N-Acetylmuramoyl-L-alanine amidase
BED32_19240	COG0802	atpase or kinase
BED32_19245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BED32_19245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BED32_19250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BED32_19265	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BED32_19270	COG1162	GTPase activity
BED32_19275	COG0688	phosphatidylethanolamine metabolic process
BED32_19280	COG3264	Mechanosensitive ion channel
BED32_19280	COG1511	domain protein
BED32_19285	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BED32_19290	COG1053	succinate dehydrogenase
BED32_19295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BED32_19300	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BED32_19305	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BED32_19315	COG2076	Multidrug Resistance protein
BED32_19325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BED32_19345	COG0459	protein refolding
BED32_19350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BED32_19365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BED32_19375	COG4232	protein-disulfide reductase activity
BED32_19380	COG1929	Belongs to the glycerate kinase type-1 family
BED32_19385	COG1309	transcriptional regulator
BED32_19395	COG1882	Formate acetyltransferase
BED32_19400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BED32_19405	COG0814	amino acid
BED32_19410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BED32_19420	COG3721	Heme iron utilization protein
BED32_19440	COG3720	iron ion transport
BED32_19445	COG4558	Periplasmic binding protein
BED32_19450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BED32_19455	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BED32_19470	COG4774	siderophore transport
BED32_19485	COG2161	toxin-antitoxin pair type II binding
BED32_19495	COG4178	(ABC) transporter
BED32_19500	COG4771	TonB-dependent receptor
BED32_19505	COG3712	iron ion homeostasis
BED32_19520	COG0425	Belongs to the sulfur carrier protein TusA family
BED32_19525	COG2391	methyltransferase activity
BED32_19685	COG2197	response regulator
BED32_19690	COG1301	dicarboxylic acid transport
BED32_19695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BED32_19700	COG3162	membrane
BED32_19705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BED32_19750	COG0138	bifunctional purine biosynthesis protein purh
BED32_19755	COG0151	Belongs to the GarS family
BED32_19770	COG3068	Protein conserved in bacteria
BED32_19775	COG1515	deoxyribonuclease V activity
BED32_19780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BED32_19785	COG2816	NAD+ diphosphatase activity
BED32_19790	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BED32_19795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BED32_19805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BED32_19810	COG2104	thiamine diphosphate biosynthetic process
BED32_19815	COG2022	thiamine diphosphate biosynthetic process
BED32_19830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BED32_19835	COG0085	RNA polymerase activity
BED32_19845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BED32_19850	COG0081	regulation of translation
BED32_19855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BED32_19860	COG0250	Participates in transcription elongation, termination and antitermination
BED32_19865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BED32_19870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BED32_19905	COG1072	(Pantothenic acid kinase))
BED32_19910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BED32_19910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BED32_19955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BED32_19960	COG1739	Uncharacterized protein family UPF0029
BED32_19965	COG0006	proline dipeptidase activity
BED32_19970	COG1024	Enoyl-CoA hydratase
BED32_19970	COG1250	3-hydroxyacyl-CoA dehydrogenase
BED32_19975	COG0183	Belongs to the thiolase family
BED32_19985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BED32_20005	COG0805	protein transport
BED32_20010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BED32_20015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BED32_20020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BED32_20030	COG2226	methyltransferase
BED32_20045	COG1966	Carbon starvation protein
BED32_20055	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BED32_20060	COG0412	Dienelactone hydrolase
BED32_20065	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BED32_20070	COG0583	DNA-binding transcription factor activity
BED32_20080	COG0679	Auxin Efflux Carrier
BED32_20085	COG0584	glycerophosphoryl diester phosphodiesterase
BED32_20090	COG3842	ATPase activity
BED32_20095	COG0395	ABC-type sugar transport system, permease component
BED32_20100	COG1175	transmembrane transport
BED32_20105	COG1653	transport
BED32_20140	COG0410	ABC transporter
BED32_20145	COG0411	ABC transporter
BED32_20150	COG4177	L-phenylalanine transmembrane transporter activity
BED32_20155	COG0559	Belongs to the binding-protein-dependent transport system permease family
BED32_20160	COG0683	leucine binding
BED32_20185	COG2177	Part of the ABC transporter FtsEX involved in
BED32_20190	COG2884	Cell division ATP-binding protein ftsE
BED32_20195	COG0552	protein localization to endoplasmic reticulum
BED32_20200	COG0742	ribosomal rna small subunit methyltransferase
BED32_20205	COG3776	membrane
BED32_20220	COG3714	YhhN family
BED32_20225	COG2217	Heavy metal translocating P-type atpase
BED32_20230	COG0425	Belongs to the sulfur carrier protein TusA family
BED32_20235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BED32_20245	COG0247	lactate metabolic process
BED32_20250	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BED32_20255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BED32_20260	COG2271	Major facilitator Superfamily
BED32_20265	COG0584	glycerophosphoryl diester phosphodiesterase
BED32_20270	COG0561	phosphatase activity
BED32_20275	COG2267	carboxylic ester hydrolase activity
BED32_20280	COG1280	lysine exporter protein (LysE YggA)
BED32_20285	COG1280	lysine exporter protein (LysE YggA)
BED32_20290	COG0514	ATP-dependent DNA helicase (RecQ)
BED32_20295	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BED32_20300	COG2050	protein possibly involved in aromatic compounds catabolism
BED32_20310	COG0598	Magnesium transport protein CorA
BED32_20315	COG5564	TIM-barrel signal transduction protein
BED32_20320	COG5441	Belongs to the UPF0261 family
BED32_20330	COG0210	DNA helicase
BED32_20335	COG1011	Hydrolase
BED32_20340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BED32_20345	COG3159	Protein conserved in bacteria
BED32_20350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BED32_20355	COG5567	small periplasmic lipoprotein
BED32_20360	COG1965	Belongs to the frataxin family
BED32_20370	COG3072	Adenylate cyclase
BED32_20375	COG0181	hydroxymethylbilane synthase activity
BED32_20380	COG1587	Uroporphyrinogen-III synthase
BED32_20385	COG2959	enzyme of heme biosynthesis
BED32_20390	COG3071	HemY protein
BED32_20435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BED32_20440	COG2244	polysaccharide biosynthetic process
BED32_20445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BED32_20450	COG0456	acetyltransferase
BED32_20455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BED32_20460	COG1088	dTDP-glucose 4,6-dehydratase activity
BED32_20465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BED32_20470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BED32_20475	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BED32_20480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BED32_20490	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BED32_20495	COG3118	belongs to the thioredoxin family
BED32_20505	COG0248	Ppx GppA phosphatase
BED32_20520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BED32_20550	COG3177	Filamentation induced by cAMP protein fic
BED32_20585	COG0582	viral genome integration into host DNA
BED32_20590	COG1609	Transcriptional regulator
BED32_20590	COG2207	Transcriptional regulator
BED32_20595	COG4214	carbohydrate transport
BED32_20605	COG4213	ABC transporter substrate-binding protein
BED32_20610	COG2115	Belongs to the xylose isomerase family
BED32_20615	COG1070	Carbohydrate kinase
BED32_20620	COG3121	Chaperone
BED32_20635	COG3274	enterobacterial common antigen metabolic process
BED32_20645	COG3276	selenocysteine insertion sequence binding
BED32_20650	COG1921	L-seryl-tRNASec selenium transferase activity
BED32_20655	COG3058	Necessary for formate dehydrogenase activity
BED32_20660	COG2864	formate dehydrogenase
BED32_20665	COG0437	4 iron, 4 sulfur cluster binding
BED32_20670	COG3383	formate dehydrogenase (NAD+) activity
BED32_20670	COG0243	molybdopterin cofactor binding
BED32_20675	COG3383	formate dehydrogenase (NAD+) activity
BED32_20675	COG0243	molybdopterin cofactor binding
BED32_20680	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BED32_20685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BED32_20690	COG0840	transmembrane signaling receptor activity
BED32_20695	COG2258	MOSC domain
BED32_20715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BED32_20725	COG3722	fumarate hydratase activity
BED32_20730	COG0246	Mannitol dehydrogenase
BED32_20735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BED32_20735	COG2213	PTS system mannitol-specific
BED32_20745	COG0751	glycine-tRNA ligase activity
BED32_20750	COG0752	glycyl-tRNA synthetase alpha subunit
BED32_20755	COG2818	Glycosylase
BED32_20760	COG0456	acetyltransferase
BED32_20790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BED32_20795	COG0366	Alpha amylase catalytic
BED32_20800	COG3977	Valine--pyruvate aminotransferase
BED32_20805	COG2985	domain, Protein
BED32_20805	COG0569	domain protein
BED32_20815	COG2814	Major facilitator Superfamily
BED32_20835	COG3152	Membrane
BED32_20845	COG0149	triose-phosphate isomerase activity
BED32_20855	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BED32_20865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BED32_20870	COG3678	ATP-independent chaperone mediated protein folding
BED32_20875	COG0745	RESPONSE REGULATOR receiver
BED32_20880	COG2205	protein histidine kinase activity
BED32_20885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BED32_20885	COG2169	Transcriptional regulator
BED32_20890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BED32_20895	COG1045	serine acetyltransferase
BED32_20900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BED32_20905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BED32_20910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BED32_20915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BED32_20920	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BED32_20925	COG4942	peptidase
BED32_20930	COG2861	carbohydrate metabolic process
BED32_20945	COG1063	alcohol dehydrogenase
BED32_20950	COG0156	8-amino-7-oxononanoate synthase activity
BED32_20955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BED32_20960	COG0859	PFAM glycosyl transferase family 9
BED32_20965	COG0859	PFAM glycosyl transferase family 9
BED32_20970	COG1519	Transferase
BED32_20980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BED32_20985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BED32_20990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BED32_20995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BED32_21000	COG2003	Belongs to the UPF0758 family
BED32_21005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BED32_21010	COG0756	dUTP diphosphatase activity
BED32_21015	COG1309	transcriptional regulator
BED32_21020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BED32_21025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BED32_21030	COG1561	YicC-like family, N-terminal region
BED32_21035	COG0582	viral genome integration into host DNA
BED32_21055	COG3561	AntA/AntB antirepressor
BED32_21135	COG5001	Diguanylate cyclase
BED32_21140	COG1024	Enoyl-CoA hydratase
BED32_21145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BED32_21160	COG2860	membrane
BED32_21175	COG1758	RNA polymerase activity
BED32_21180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BED32_21185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BED32_21190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BED32_21195	COG0786	glutamate:sodium symporter activity
BED32_21200	COG2233	PERMEase
BED32_21205	COG2982	Protein involved in outer membrane biogenesis
BED32_21220	COG3423	Transcriptional regulator
BED32_21225	COG0456	acetyltransferase
BED32_21230	COG1490	D-aminoacyl-tRNA deacylase activity
BED32_21235	COG1295	ribonuclease BN
BED32_21240	COG1011	Hydrolase
BED32_21250	COG0174	glutamine synthetase
BED32_21260	COG3852	Histidine kinase
BED32_21270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BED32_21275	COG3078	GTPase activator activity
BED32_21280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BED32_21285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BED32_21285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BED32_21290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BED32_21295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BED32_21300	COG3084	Protein conserved in bacteria
BED32_21310	COG1763	Mo-molybdopterin cofactor biosynthetic process
BED32_21345	COG2186	Transcriptional regulator
BED32_21350	COG0477	Major facilitator Superfamily
BED32_21355	COG1609	Transcriptional regulator
BED32_21360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BED32_21365	COG1879	ABC-type sugar transport system periplasmic component
BED32_21370	COG1172	Belongs to the binding-protein-dependent transport system permease family
BED32_21380	COG1869	D-ribose catabolic process
BED32_21385	COG3158	transport of potassium into the cell
BED32_21390	COG0714	Associated with various cellular activities
BED32_21395	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BED32_21405	COG2502	aspartate--ammonia ligase
BED32_21410	COG1522	sequence-specific DNA binding
BED32_21415	COG0716	FMN binding
BED32_21420	COG0445	tRNA wobble uridine modification
BED32_21425	COG0357	Ribosomal RNA small subunit methyltransferase G
BED32_21430	COG3312	ion transport
BED32_21435	COG0356	it plays a direct role in the translocation of protons across the membrane
BED32_21445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BED32_21450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BED32_21455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BED32_21460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BED32_21465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BED32_21470	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BED32_21475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BED32_21480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BED32_21485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BED32_21490	COG0573	inorganic phosphate transmembrane transporter activity
BED32_21495	COG0581	inorganic phosphate transmembrane transporter activity
BED32_21505	COG0704	Plays a role in the regulation of phosphate uptake
BED32_21515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BED32_21525	COG0765	amino acid transport
BED32_21530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BED32_21535	COG2252	PERMEase
BED32_21545	COG4566	intracellular signal transduction
BED32_21555	COG0431	NADPH-dependent FMN reductase
BED32_21560	COG0840	transmembrane signaling receptor activity
BED32_21565	COG2011	ABC-type metal ion transport system permease component
BED32_21580	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BED32_21585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BED32_21590	COG0706	membrane insertase activity
BED32_21600	COG0594	ribonuclease P activity
BED32_21605	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BED32_21645	COG1388	LysM domain
BED32_21645	COG1470	cell adhesion involved in biofilm formation
BED32_21970	COG2831	hemolysin activation secretion protein
BED32_21975	COG3210	domain, Protein
BED32_22110	COG1388	LysM domain
BED32_22110	COG1470	cell adhesion involved in biofilm formation