locus-tag	class	description
YE105_C0001	COG0716	FMN binding
YE105_C0002	COG1522	sequence-specific DNA binding
YE105_C0003	COG2502	aspartate--ammonia ligase
YE105_C0005	COG2425	protein containing a von Willebrand factor type A (vWA) domain
YE105_C0006	COG0714	Associated with various cellular activities
YE105_C0007	COG3158	transport of potassium into the cell
YE105_C0008	COG1869	D-ribose catabolic process
YE105_C0010	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C0011	COG1879	ABC-type sugar transport system periplasmic component
YE105_C0012	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_C0013	COG1609	Transcriptional regulator
YE105_C0014	COG0477	Major facilitator Superfamily
YE105_C0015	COG2186	Transcriptional regulator
YE105_C0018	COG1763	Mo-molybdopterin cofactor biosynthetic process
YE105_C0020	COG3084	Protein conserved in bacteria
YE105_C0021	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YE105_C0022	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YE105_C0023	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_C0023	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_C0025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YE105_C0026	COG3078	GTPase activator activity
YE105_C0027	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YE105_C0029	COG3852	Histidine kinase
YE105_C0031	COG0174	glutamine synthetase
YE105_C0033	COG1011	Hydrolase
YE105_C0034	COG1295	ribonuclease BN
YE105_C0035	COG1490	D-aminoacyl-tRNA deacylase activity
YE105_C0036	COG0456	acetyltransferase
YE105_C0037	COG3423	Transcriptional regulator
YE105_C0040	COG2982	Protein involved in outer membrane biogenesis
YE105_C0041	COG2233	PERMEase
YE105_C0042	COG0786	glutamate:sodium symporter activity
YE105_C0044	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YE105_C0045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YE105_C0046	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YE105_C0047	COG1758	RNA polymerase activity
YE105_C0049	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YE105_C0050	COG2860	membrane
YE105_C0052	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YE105_C0053	COG1024	Enoyl-CoA hydratase
YE105_C0054	COG5001	Diguanylate cyclase
YE105_C0056	COG1561	YicC-like family, N-terminal region
YE105_C0057	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YE105_C0058	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YE105_C0059	COG1309	transcriptional regulator
YE105_C0060	COG0756	dUTP diphosphatase activity
YE105_C0061	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YE105_C0062	COG2003	Belongs to the UPF0758 family
YE105_C0063	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YE105_C0064	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YE105_C0065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YE105_C0066	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YE105_C0068	COG1519	Transferase
YE105_C0069	COG0859	PFAM glycosyl transferase family 9
YE105_C0070	COG0859	PFAM glycosyl transferase family 9
YE105_C0071	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_C0072	COG0156	8-amino-7-oxononanoate synthase activity
YE105_C0073	COG1063	alcohol dehydrogenase
YE105_C0076	COG2861	carbohydrate metabolic process
YE105_C0077	COG4942	peptidase
YE105_C0078	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YE105_C0079	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YE105_C0080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YE105_C0081	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YE105_C0082	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YE105_C0083	COG1045	serine acetyltransferase
YE105_C0084	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YE105_C0085	COG2169	Transcriptional regulator
YE105_C0085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YE105_C0086	COG2205	protein histidine kinase activity
YE105_C0087	COG0745	RESPONSE REGULATOR receiver
YE105_C0088	COG3678	ATP-independent chaperone mediated protein folding
YE105_C0089	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
YE105_C0091	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YE105_C0093	COG0149	triose-phosphate isomerase activity
YE105_C0095	COG3152	Membrane
YE105_C0099	COG2814	Major facilitator Superfamily
YE105_C0100	COG1494	fructose-1,6-bisphosphatase
YE105_C0102	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YE105_C0103	COG3074	FtsZ-dependent cytokinesis
YE105_C0104	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YE105_C0105	COG1575	Belongs to the MenA family. Type 1 subfamily
YE105_C0106	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YE105_C0107	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YE105_C0108	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YE105_C0109	COG1609	Transcriptional regulator
YE105_C0110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YE105_C0111	COG0254	rRNA binding
YE105_C0112	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YE105_C0113	COG0626	cystathionine gamma-synthase activity
YE105_C0114	COG0527	aspartate kinase activity
YE105_C0114	COG0460	homoserine dehydrogenase
YE105_C0116	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YE105_C0119	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YE105_C0120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YE105_C0122	COG0165	Argininosuccinate lyase
YE105_C0123	COG1629	transport
YE105_C0130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_C0131	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YE105_C0131	COG0678	peroxiredoxin activity
YE105_C0133	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_C0134	COG1309	transcriptional regulator
YE105_C0136	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YE105_C0138	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YE105_C0139	COG1879	ABC-type sugar transport system periplasmic component
YE105_C0140	COG1129	ABC transporter
YE105_C0141	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C0142	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C0143	COG0583	DNA-binding transcription factor activity
YE105_C0144	COG3085	chromosome segregation
YE105_C0147	COG3978	acetolactate synthase activity
YE105_C0148	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YE105_C0149	COG0129	dihydroxy-acid dehydratase activity
YE105_C0153	COG0583	DNA-binding transcription factor activity
YE105_C0154	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YE105_C0160	COG3121	Chaperone
YE105_C0163	COG3121	Chaperone
YE105_C0165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YE105_C0168	COG0248	Ppx GppA phosphatase
YE105_C0170	COG3118	belongs to the thioredoxin family
YE105_C0171	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YE105_C0172	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YE105_C0173	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YE105_C0174	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YE105_C0175	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YE105_C0176	COG1088	dTDP-glucose 4,6-dehydratase activity
YE105_C0177	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YE105_C0178	COG0456	acetyltransferase
YE105_C0179	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YE105_C0180	COG2244	polysaccharide biosynthetic process
YE105_C0181	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YE105_C0184	COG1113	amino acid transport
YE105_C0185	COG3071	HemY protein
YE105_C0186	COG2959	enzyme of heme biosynthesis
YE105_C0187	COG1587	Uroporphyrinogen-III synthase
YE105_C0188	COG0181	hydroxymethylbilane synthase activity
YE105_C0189	COG3072	Adenylate cyclase
YE105_C0190	COG1965	Belongs to the frataxin family
YE105_C0191	COG5567	small periplasmic lipoprotein
YE105_C0192	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YE105_C0193	COG3159	Protein conserved in bacteria
YE105_C0194	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YE105_C0195	COG1011	Hydrolase
YE105_C0196	COG0210	DNA helicase
YE105_C0198	COG5441	Belongs to the UPF0261 family
YE105_C0199	COG5564	TIM-barrel signal transduction protein
YE105_C0200	COG0598	Magnesium transport protein CorA
YE105_C0202	COG2050	protein possibly involved in aromatic compounds catabolism
YE105_C0203	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YE105_C0204	COG0514	ATP-dependent DNA helicase (RecQ)
YE105_C0205	COG1280	lysine exporter protein (LysE YggA)
YE105_C0206	COG1280	lysine exporter protein (LysE YggA)
YE105_C0207	COG2267	carboxylic ester hydrolase activity
YE105_C0208	COG0561	phosphatase activity
YE105_C0209	COG0584	glycerophosphoryl diester phosphodiesterase
YE105_C0210	COG2271	Major facilitator Superfamily
YE105_C0211	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YE105_C0212	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
YE105_C0213	COG0247	lactate metabolic process
YE105_C0215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YE105_C0216	COG0425	Belongs to the sulfur carrier protein TusA family
YE105_C0217	COG2217	Heavy metal translocating P-type atpase
YE105_C0218	COG3714	YhhN family
YE105_C0221	COG3776	membrane
YE105_C0222	COG0742	ribosomal rna small subunit methyltransferase
YE105_C0223	COG0552	protein localization to endoplasmic reticulum
YE105_C0224	COG2884	Cell division ATP-binding protein ftsE
YE105_C0225	COG2177	Part of the ABC transporter FtsEX involved in
YE105_C0231	COG0683	leucine binding
YE105_C0232	COG0559	Belongs to the binding-protein-dependent transport system permease family
YE105_C0233	COG4177	L-phenylalanine transmembrane transporter activity
YE105_C0234	COG0411	ABC transporter
YE105_C0235	COG0410	ABC transporter
YE105_C0242	COG1653	transport
YE105_C0243	COG1175	transmembrane transport
YE105_C0244	COG0395	ABC-type sugar transport system, permease component
YE105_C0245	COG3842	ATPase activity
YE105_C0246	COG0584	glycerophosphoryl diester phosphodiesterase
YE105_C0247	COG0679	Auxin Efflux Carrier
YE105_C0248	COG0583	DNA-binding transcription factor activity
YE105_C0249	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YE105_C0250	COG0412	Dienelactone hydrolase
YE105_C0251	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YE105_C0254	COG1966	Carbon starvation protein
YE105_C0255	COG0586	Pfam SNARE associated Golgi protein
YE105_C0256	COG1322	Protein conserved in bacteria
YE105_C0257	COG2226	methyltransferase
YE105_C0259	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YE105_C0260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YE105_C0261	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YE105_C0262	COG0805	protein transport
YE105_C0266	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YE105_C0268	COG0183	Belongs to the thiolase family
YE105_C0269	COG1024	Enoyl-CoA hydratase
YE105_C0269	COG1250	3-hydroxyacyl-CoA dehydrogenase
YE105_C0270	COG0006	proline dipeptidase activity
YE105_C0271	COG1739	Uncharacterized protein family UPF0029
YE105_C0272	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YE105_C0278	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
YE105_C0278	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
YE105_C0279	COG1072	(Pantothenic acid kinase))
YE105_C0281	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YE105_C0282	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YE105_C0283	COG0250	Participates in transcription elongation, termination and antitermination
YE105_C0284	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YE105_C0285	COG0081	regulation of translation
YE105_C0286	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YE105_C0288	COG0085	RNA polymerase activity
YE105_C0289	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YE105_C0291	COG2022	thiamine diphosphate biosynthetic process
YE105_C0292	COG2104	thiamine diphosphate biosynthetic process
YE105_C0293	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YE105_C0295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YE105_C0296	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
YE105_C0297	COG2816	NAD+ diphosphatase activity
YE105_C0298	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YE105_C0299	COG1515	deoxyribonuclease V activity
YE105_C0300	COG3068	Protein conserved in bacteria
YE105_C0303	COG0151	Belongs to the GarS family
YE105_C0304	COG0138	bifunctional purine biosynthesis protein purh
YE105_C0305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YE105_C0306	COG3162	membrane
YE105_C0307	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YE105_C0308	COG1301	dicarboxylic acid transport
YE105_C0309	COG2197	response regulator
YE105_C0310	COG0784	Response regulator, receiver
YE105_C0310	COG2205	protein histidine kinase activity
YE105_C0310	COG5002	protein histidine kinase activity
YE105_C0342	COG2391	methyltransferase activity
YE105_C0343	COG0425	Belongs to the sulfur carrier protein TusA family
YE105_C0346	COG3712	iron ion homeostasis
YE105_C0347	COG4771	TonB-dependent receptor
YE105_C0348	COG4178	(ABC) transporter
YE105_C0349	COG0612	Peptidase, M16
YE105_C0350	COG2161	toxin-antitoxin pair type II binding
YE105_C0351	COG4115	mRNA cleavage
YE105_C0352	COG3264	Mechanosensitive ion channel
YE105_C0352	COG1511	domain protein
YE105_C0353	COG4774	siderophore transport
YE105_C0354	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_C0355	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YE105_C0356	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_C0357	COG4558	Periplasmic binding protein
YE105_C0358	COG3720	iron ion transport
YE105_C0362	COG3721	Heme iron utilization protein
YE105_C0364	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YE105_C0365	COG0814	amino acid
YE105_C0366	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YE105_C0367	COG1882	Formate acetyltransferase
YE105_C0368	COG1309	transcriptional regulator
YE105_C0369	COG1929	Belongs to the glycerate kinase type-1 family
YE105_C0370	COG4232	protein-disulfide reductase activity
YE105_C0372	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YE105_C0375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YE105_C0376	COG0459	protein refolding
YE105_C0379	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YE105_C0381	COG2076	Multidrug Resistance protein
YE105_C0383	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YE105_C0384	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YE105_C0385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YE105_C0386	COG1053	succinate dehydrogenase
YE105_C0387	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
YE105_C0388	COG1511	domain protein
YE105_C0388	COG3264	Mechanosensitive ion channel
YE105_C0389	COG0688	phosphatidylethanolamine metabolic process
YE105_C0390	COG1162	GTPase activity
YE105_C0391	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YE105_C0392	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YE105_C0392	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YE105_C0393	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YE105_C0394	COG0802	atpase or kinase
YE105_C0395	COG0860	N-Acetylmuramoyl-L-alanine amidase
YE105_C0396	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YE105_C0397	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YE105_C0398	COG1923	regulation of RNA biosynthetic process
YE105_C0399	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YE105_C0400	COG0330	HflC and HflK could
YE105_C0401	COG0330	HflC and HflK could
YE105_C0402	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YE105_C0403	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YE105_C0404	COG1959	2 iron, 2 sulfur cluster binding
YE105_C0405	COG0557	exoribonuclease II activity
YE105_C0406	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YE105_C0407	COG1960	acyl-CoA dehydrogenase activity
YE105_C0408	COG3650	response to hydrogen peroxide
YE105_C0409	COG1073	alpha beta
YE105_C0411	COG0360	Binds together with S18 to 16S ribosomal RNA
YE105_C0412	COG2965	DNA replication, synthesis of RNA primer
YE105_C0413	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YE105_C0414	COG0359	binds to the 23S rRNA
YE105_C0416	COG3061	Opacity-associated protein A
YE105_C0417	COG0545	Peptidyl-prolyl cis-trans isomerase
YE105_C0419	COG0737	Belongs to the 5'-nucleotidase family
YE105_C0420	COG1218	3'(2'),5'-bisphosphate nucleotidase
YE105_C0421	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YE105_C0423	COG1253	flavin adenine dinucleotide binding
YE105_C0424	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YE105_C0428	COG2105	PFAM AIG2 family protein
YE105_C0429	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YE105_C0431	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YE105_C0432	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YE105_C0434	COG1438	arginine binding
YE105_C0435	COG0039	L-malate dehydrogenase activity
YE105_C0436	COG3423	Transcriptional regulator
YE105_C0438	COG0142	geranyltranstransferase activity
YE105_C0439	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YE105_C0440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YE105_C0441	COG0697	spore germination
YE105_C0442	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YE105_C0443	COG0642	Histidine kinase
YE105_C0444	COG0745	RESPONSE REGULATOR receiver
YE105_C0445	COG2027	D-alanyl-D-alanine carboxypeptidase
YE105_C0446	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YE105_C0447	COG1534	Rna-binding protein
YE105_C0448	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YE105_C0449	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YE105_C0450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YE105_C0451	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YE105_C0452	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YE105_C0453	COG0779	Required for maturation of 30S ribosomal subunits
YE105_C0454	COG0195	Participates in both transcription termination and antitermination
YE105_C0455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YE105_C0456	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YE105_C0457	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YE105_C0458	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YE105_C0459	COG1185	polyribonucleotide nucleotidyltransferase activity
YE105_C0461	COG0513	Belongs to the DEAD box helicase family
YE105_C0463	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YE105_C0465	COG0814	amino acid
YE105_C0466	COG3681	Belongs to the UPF0597 family
YE105_C0470	COG3153	acetyltransferase
YE105_C0471	COG2827	Endonuclease containing a URI domain
YE105_C0472	COG0531	amino acid
YE105_C0473	COG1982	Orn Lys Arg decarboxylase major
YE105_C0476	COG1653	transport
YE105_C0478	COG0395	ABC-type sugar transport system, permease component
YE105_C0479	COG3842	ATPase activity
YE105_C0481	COG3787	Belongs to the UPF0306 family
YE105_C0484	COG0702	epimerase
YE105_C0485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YE105_C0486	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YE105_C0487	COG3454	Phosphonate metabolism
YE105_C0488	COG4778	phosphonate C-P lyase system protein PhnL
YE105_C0489	COG4107	phosphonate C-P lyase system protein PhnK
YE105_C0490	COG3627	carbon phosphorus lyase activity
YE105_C0491	COG3626	phosphonate metabolism
YE105_C0492	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YE105_C0493	COG3624	Phosphonate C-P lyase system protein PhnG
YE105_C0494	COG2188	Transcriptional regulator
YE105_C0501	COG4608	Belongs to the ABC transporter superfamily
YE105_C0502	COG0444	Belongs to the ABC transporter superfamily
YE105_C0504	COG0601	transmembrane transport
YE105_C0506	COG2731	YhcH YjgK YiaL family protein
YE105_C0508	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YE105_C0511	COG2927	DNA polymerase III (CHI subunit)
YE105_C0512	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YE105_C0513	COG0795	lipopolysaccharide-transporting ATPase activity
YE105_C0514	COG0795	lipopolysaccharide-transporting ATPase activity
YE105_C0523	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YE105_C0523	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
YE105_C0524	COG0454	-acetyltransferase
YE105_C0533	COG3328	transposase activity
YE105_C0536	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YE105_C0537	COG1830	Aldolase
YE105_C0538	COG1879	ABC-type sugar transport system periplasmic component
YE105_C0539	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C0540	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C0541	COG1129	ABC transporter
YE105_C0542	COG2390	Transcriptional regulator
YE105_C0543	COG1070	Carbohydrate kinase
YE105_C0544	COG0859	PFAM glycosyl transferase family 9
YE105_C0547	COG2235	arginine
YE105_C0548	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C0549	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_C0551	COG2376	Dihydroxyacetone kinase
YE105_C0552	COG1461	Dihydroxyacetone kinase
YE105_C0553	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C0553	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
YE105_C0553	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YE105_C0555	COG2192	nodulation
YE105_C0561	COG3284	Transcriptional regulator
YE105_C0569	COG4772	TonB-dependent receptor
YE105_C0570	COG3706	GGDEF domain
YE105_C0573	COG0583	DNA-binding transcription factor activity
YE105_C0574	COG0667	Aldo Keto reductase
YE105_C0575	COG2813	Specifically methylates the guanine in position
YE105_C0576	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YE105_C0577	COG0456	acetyltransferase
YE105_C0578	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
YE105_C0579	COG2823	Periplasmic or secreted lipoprotein
YE105_C0581	COG4667	esterase of the alpha-beta hydrolase superfamily
YE105_C0582	COG0084	hydrolase, TatD family'
YE105_C0583	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YE105_C0584	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YE105_C0585	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
YE105_C0586	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YE105_C0587	COG0813	purine-nucleoside phosphorylase activity
YE105_C0588	COG3726	membrane protein affecting hemolysin expression
YE105_C0589	COG0560	Phosphoserine phosphatase
YE105_C0592	COG0604	alcohol dehydrogenase
YE105_C0595	COG0488	(ABC) transporter
YE105_C0596	COG2885	chlorophyll binding
YE105_C0597	COG2199	diguanylate cyclase activity
YE105_C0599	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YE105_C0600	COG0741	lytic transglycosylase activity
YE105_C0601	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YE105_C0602	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
YE105_C0603	COG0406	alpha-ribazole phosphatase activity
YE105_C0604	COG3708	Transcriptional regulator
YE105_C0604	COG2207	Transcriptional regulator
YE105_C0605	COG3045	CreA protein
YE105_C0606	COG0745	RESPONSE REGULATOR receiver
YE105_C0608	COG0083	homoserine kinase activity
YE105_C0610	COG3022	response to hydroperoxide
YE105_C0611	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YE105_C0612	COG0521	Mo-molybdopterin cofactor biosynthetic process
YE105_C0614	COG1584	GPR1 FUN34 yaaH family protein
YE105_C0615	COG0443	Heat shock 70 kDa protein
YE105_C0616	COG0484	heat shock protein binding
YE105_C0617	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YE105_C0618	COG0583	DNA-binding transcription factor activity
YE105_C0619	COG0268	Binds directly to 16S ribosomal RNA
YE105_C0620	COG0196	riboflavin kinase activity
YE105_C0621	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YE105_C0622	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YE105_C0623	COG1047	Peptidyl-prolyl cis-trans
YE105_C0624	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YE105_C0625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YE105_C0626	COG0505	Belongs to the CarA family
YE105_C0627	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YE105_C0628	COG1280	lysine exporter protein (LysE YggA)
YE105_C0629	COG2966	Psort location CytoplasmicMembrane, score
YE105_C0630	COG3610	response to peptide
YE105_C0631	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YE105_C0632	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YE105_C0633	COG2967	ApaG domain
YE105_C0634	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YE105_C0636	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YE105_C0637	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YE105_C0638	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YE105_C0639	COG0564	pseudouridine synthase activity
YE105_C0641	COG1470	cell adhesion involved in biofilm formation
YE105_C0641	COG1388	LysM domain
YE105_C0642	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YE105_C0643	COG0417	DNA replication proofreading
YE105_C0644	COG0586	Pfam SNARE associated Golgi protein
YE105_C0646	COG1178	ABC-type Fe3 transport system permease component
YE105_C0647	COG4143	(ABC) transporter
YE105_C0649	COG4533	DNA binding
YE105_C0650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YE105_C0653	COG2814	Major facilitator Superfamily
YE105_C0655	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YE105_C0656	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YE105_C0657	COG0564	pseudouridine synthase activity
YE105_C0659	COG0542	response to heat
YE105_C0662	COG1605	Chorismate mutase
YE105_C0662	COG0077	Prephenate dehydratase
YE105_C0663	COG1605	Chorismate mutase
YE105_C0663	COG0287	Prephenate dehydrogenase
YE105_C0664	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YE105_C0665	COG3279	Response regulator of the LytR AlgR family
YE105_C0666	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YE105_C0667	COG3137	Salt-induced outer membrane protein
YE105_C0668	COG0335	large ribosomal subunit rRNA binding
YE105_C0669	COG0336	Belongs to the RNA methyltransferase TrmD family
YE105_C0670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YE105_C0671	COG0228	four-way junction DNA binding
YE105_C0672	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YE105_C0673	COG4137	Cytochrome C assembly protein
YE105_C0674	COG4536	flavin adenine dinucleotide binding
YE105_C0675	COG1854	S-ribosylhomocysteine lyase activity
YE105_C0676	COG2918	glutathione biosynthetic process
YE105_C0677	COG1238	metal cluster binding
YE105_C0678	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_C0679	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YE105_C0680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YE105_C0681	COG2137	regulation of response to DNA damage stimulus
YE105_C0682	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YE105_C0685	COG3381	protein complex oligomerization
YE105_C0686	COG3302	dmso reductase anchor subunit
YE105_C0687	COG0437	4 iron, 4 sulfur cluster binding
YE105_C0688	COG0243	molybdopterin cofactor binding
YE105_C0689	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_C0689	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_C0691	COG0559	Belongs to the binding-protein-dependent transport system permease family
YE105_C0692	COG4177	L-phenylalanine transmembrane transporter activity
YE105_C0693	COG1137	ATPase activity
YE105_C0694	COG1129	ABC transporter
YE105_C0706	COG0640	Transcriptional regulator
YE105_C0707	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YE105_C0709	COG1858	cytochrome C peroxidase
YE105_C0710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YE105_C0712	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C0716	COG1538	Outer membrane efflux protein
YE105_C0718	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C0725	COG3539	Fimbrial protein
YE105_C0726	COG3539	Fimbrial protein
YE105_C0728	COG3121	Chaperone
YE105_C0729	COG3188	usher protein
YE105_C0734	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YE105_C0735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YE105_C0736	COG1388	LysM domain
YE105_C0736	COG4942	peptidase
YE105_C0737	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YE105_C0738	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YE105_C0739	COG0585	pseudouridine synthase activity
YE105_C0740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YE105_C0742	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
YE105_C0744	COG0529	Catalyzes the synthesis of activated sulfate
YE105_C0745	COG2895	sulfate adenylyltransferase (ATP) activity
YE105_C0746	COG0175	sulfate reduction
YE105_C0747	COG1648	precorrin-2 dehydrogenase activity
YE105_C0747	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YE105_C0748	COG2234	aminopeptidase activity
YE105_C0751	COG0175	sulfate reduction
YE105_C0752	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YE105_C0753	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YE105_C0754	COG0720	synthase
YE105_C0757	COG0602	queuosine metabolic process
YE105_C0763	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YE105_C0764	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YE105_C0765	COG0583	DNA-binding transcription factor activity
YE105_C0767	COG1279	arginine transmembrane transporter activity
YE105_C0769	COG0814	amino acid
YE105_C0770	COG3033	Beta-eliminating lyase
YE105_C0772	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YE105_C0773	COG0473	3-isopropylmalate dehydrogenase activity
YE105_C0774	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YE105_C0776	COG1022	Amp-dependent synthetase and ligase
YE105_C0777	COG0028	Belongs to the TPP enzyme family
YE105_C0779	COG1609	Transcriptional regulator
YE105_C0781	COG2001	Belongs to the MraZ family
YE105_C0782	COG0275	rRNA processing
YE105_C0783	COG3116	cell division
YE105_C0784	COG0768	penicillin binding
YE105_C0785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YE105_C0786	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YE105_C0787	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YE105_C0789	COG0772	Belongs to the SEDS family
YE105_C0790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YE105_C0791	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YE105_C0793	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YE105_C0794	COG0849	cell division
YE105_C0795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YE105_C0799	COG0653	protein targeting
YE105_C0800	COG0494	nUDIX hydrolase
YE105_C0801	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YE105_C0803	COG0237	dephospho-CoA kinase activity
YE105_C0804	COG0516	GMP reductase activity
YE105_C0805	COG1459	type II secretion system
YE105_C0806	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YE105_C0807	COG4969	Belongs to the N-Me-Phe pilin family
YE105_C0810	COG3725	Membrane protein required for beta-lactamase induction
YE105_C0811	COG1113	amino acid transport
YE105_C0812	COG2186	Transcriptional regulator
YE105_C0813	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YE105_C0814	COG0508	dehydrogenase complex catalyzes the overall conversion of
YE105_C0815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_C0817	COG4977	sequence-specific DNA binding
YE105_C0820	COG3112	Uncharacterised protein family (UPF0231)
YE105_C0821	COG0697	spore germination
YE105_C0824	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
YE105_C0825	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YE105_C0827	COG2132	Multicopper oxidase
YE105_C0828	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YE105_C0829	COG0288	reversible hydration of carbon dioxide
YE105_C0830	COG1131	(ABC) transporter
YE105_C0831	COG0842	Transport permease protein
YE105_C0832	COG0726	polysaccharide deacetylase
YE105_C0833	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
YE105_C0834	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YE105_C0835	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YE105_C0836	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YE105_C0839	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YE105_C0840	COG1489	DNA binding
YE105_C0841	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YE105_C0842	COG1643	Atp-dependent helicase
YE105_C0843	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YE105_C0844	COG1120	ATPase activity
YE105_C0845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YE105_C0846	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_C0848	COG2223	nitrite transmembrane transporter activity
YE105_C0849	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YE105_C0851	COG0316	Belongs to the HesB IscA family
YE105_C0852	COG2860	membrane
YE105_C0854	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YE105_C0855	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YE105_C0856	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YE105_C0857	COG3850	Histidine kinase
YE105_C0857	COG2205	protein histidine kinase activity
YE105_C0857	COG3437	response regulator, receiver
YE105_C0857	COG4999	Histidine kinase
YE105_C0858	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YE105_C0859	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YE105_C0860	COG3956	TIGRFAM MazG family protein
YE105_C0861	COG0504	CTP synthase activity
YE105_C0862	COG0148	phosphopyruvate hydratase activity
YE105_C0863	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YE105_C0864	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
YE105_C0865	COG3079	Belongs to the UPF0149 family
YE105_C0866	COG0006	proline dipeptidase activity
YE105_C0867	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YE105_C0868	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YE105_C0869	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YE105_C0870	COG0509	glycine decarboxylation via glycine cleavage system
YE105_C0871	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YE105_C0871	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YE105_C0873	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C0875	COG1272	protein, Hemolysin III
YE105_C0877	COG0354	folic acid binding
YE105_C0878	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YE105_C0880	COG0745	RESPONSE REGULATOR receiver
YE105_C0881	COG2205	protein histidine kinase activity
YE105_C0882	COG4452	Inner membrane protein CreD
YE105_C0883	COG0716	FMN binding
YE105_C0884	COG4974	Belongs to the 'phage' integrase family
YE105_C0885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YE105_C0886	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YE105_C0887	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
YE105_C0888	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YE105_C0895	COG2944	sequence-specific DNA binding
YE105_C0896	COG3328	transposase activity
YE105_C0898	COG4319	ketosteroid isomerase
YE105_C0899	COG3706	GGDEF domain
YE105_C0900	COG1522	sequence-specific DNA binding
YE105_C0903	COG2271	Major facilitator Superfamily
YE105_C0905	COG0484	heat shock protein binding
YE105_C0907	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C0908	COG1733	regulation of RNA biosynthetic process
YE105_C0909	COG0288	reversible hydration of carbon dioxide
YE105_C0915	COG2165	general secretion pathway protein
YE105_C0921	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
YE105_C0928	COG2814	Major facilitator Superfamily
YE105_C0929	COG0583	DNA-binding transcription factor activity
YE105_C0930	COG0019	diaminopimelate decarboxylase activity
YE105_C0931	COG1609	Transcriptional regulator
YE105_C0933	COG0204	Acyl-transferase
YE105_C0933	COG0318	PFAM AMP-dependent synthetase and ligase
YE105_C0934	COG0477	Major facilitator Superfamily
YE105_C0935	COG0667	Aldo Keto reductase
YE105_C0936	COG0861	Integral membrane protein TerC family
YE105_C0937	COG3066	DNA modification
YE105_C0938	COG1051	belongs to the nudix hydrolase family
YE105_C0940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YE105_C0941	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YE105_C0945	COG4967	type IV pilus modification protein PilV
YE105_C0946	COG1025	Belongs to the peptidase M16 family
YE105_C0947	COG1074	ATP-dependent DNA helicase activity
YE105_C0948	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YE105_C0949	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YE105_C0949	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YE105_C0950	COG0860	N-Acetylmuramoyl-L-alanine amidase
YE105_C0951	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YE105_C0952	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YE105_C0953	COG2166	iron-sulfur cluster assembly
YE105_C0954	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YE105_C0956	COG0583	DNA-binding transcription factor activity
YE105_C0957	COG2363	Small membrane protein
YE105_C0958	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
YE105_C0959	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_C0960	COG1611	Belongs to the LOG family
YE105_C0961	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YE105_C0961	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YE105_C0963	COG3098	single-species biofilm formation
YE105_C0964	COG0564	pseudouridine synthase activity
YE105_C0967	COG2171	N-acyltransferase activity
YE105_C0968	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YE105_C0969	COG0024	Methionine aminopeptidase
YE105_C0970	COG0052	Belongs to the universal ribosomal protein uS2 family
YE105_C0971	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YE105_C0972	COG0528	UMP kinase activity
YE105_C0973	COG0233	cytoplasmic translational termination
YE105_C0974	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YE105_C0975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YE105_C0976	COG0575	Belongs to the CDS family
YE105_C0977	COG0750	zinc metalloprotease
YE105_C0979	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YE105_C0980	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YE105_C0981	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YE105_C0982	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YE105_C0983	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YE105_C0984	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YE105_C0986	COG0825	malonyl-CoA metabolic process
YE105_C0988	COG0346	lactoylglutathione lyase activity
YE105_C0989	COG0037	tRNA processing
YE105_C0991	COG4568	rho-dependent transcription termination
YE105_C0993	COG4681	YaeQ
YE105_C0995	COG3015	lipoprotein NlpE involved in copper resistance
YE105_C0996	COG0442	prolyl-tRNA aminoacylation
YE105_C0997	COG1720	tRNA m6t6A37 methyltransferase activity
YE105_C0999	COG1464	Belongs to the NlpA lipoprotein family
YE105_C1000	COG2011	ABC-type metal ion transport system permease component
YE105_C1002	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YE105_C1003	COG5544	Lipoprotein
YE105_C1004	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YE105_C1005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YE105_C1005	COG0045	succinate-CoA ligase (ADP-forming) activity
YE105_C1005	COG1042	CoA-binding domain protein
YE105_C1007	COG3118	belongs to the thioredoxin family
YE105_C1008	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YE105_C1010	COG2814	Major facilitator Superfamily
YE105_C1011	COG1566	PFAM secretion protein HlyD family protein
YE105_C1012	COG1538	Outer membrane efflux protein
YE105_C1013	COG1846	Transcriptional regulator
YE105_C1015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YE105_C1016	COG2814	Major facilitator Superfamily
YE105_C1023	COG0765	amino acid transport
YE105_C1024	COG0765	amino acid transport
YE105_C1026	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YE105_C1029	COG0436	Aminotransferase
YE105_C1030	COG0235	Class ii aldolase
YE105_C1031	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
YE105_C1032	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
YE105_C1033	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YE105_C1034	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
YE105_C1035	COG2831	hemolysin activation secretion protein
YE105_C1037	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YE105_C1038	COG1960	acyl-CoA dehydrogenase activity
YE105_C1040	COG0121	glutamine amidotransferase
YE105_C1041	COG3034	peptidoglycan biosynthetic process
YE105_C1042	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_C1043	COG1805	sodium ion transport
YE105_C1044	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_C1045	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_C1046	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_C1047	COG2871	sodium ion transport
YE105_C1048	COG1477	protein flavinylation
YE105_C1049	COG2991	Protein conserved in bacteria
YE105_C1052	COG1181	Belongs to the D-alanine--D-alanine ligase family
YE105_C1053	COG2964	Protein conserved in bacteria
YE105_C1056	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YE105_C1057	COG2195	Cleaves the N-terminal amino acid of tripeptides
YE105_C1059	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
YE105_C1062	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YE105_C1063	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YE105_C1064	COG2188	Transcriptional regulator
YE105_C1069	COG3459	Glycosyltransferase 36 associated
YE105_C1072	COG2226	methyltransferase
YE105_C1078	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YE105_C1080	COG3123	guanosine phosphorylase activity
YE105_C1081	COG2974	May be involved in recombination
YE105_C1082	COG1940	carbohydrate kinase activity
YE105_C1083	COG0419	ATPase involved in DNA repair
YE105_C1084	COG0420	3'-5' exonuclease activity
YE105_C1085	COG0745	RESPONSE REGULATOR receiver
YE105_C1086	COG5002	protein histidine kinase activity
YE105_C1088	COG1114	Component of the transport system for branched-chain amino acids
YE105_C1090	COG0366	Alpha amylase catalytic
YE105_C1093	COG0450	alkyl hydroperoxide reductase
YE105_C1094	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YE105_C1095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YE105_C1097	COG0343	queuine tRNA-ribosyltransferase activity
YE105_C1098	COG1862	Preprotein translocase
YE105_C1099	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YE105_C1100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YE105_C1102	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YE105_C1103	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YE105_C1103	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YE105_C1104	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YE105_C1105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YE105_C1106	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YE105_C1107	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YE105_C1109	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YE105_C1110	COG0142	geranyltranstransferase activity
YE105_C1112	COG0301	tRNA thio-modification
YE105_C1112	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YE105_C1113	COG0693	protein deglycase activity
YE105_C1114	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YE105_C1115	COG1666	GTP binding
YE105_C1116	COG2814	Major facilitator Superfamily
YE105_C1117	COG0109	protoheme IX farnesyltransferase activity
YE105_C1118	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YE105_C1119	COG1845	cytochrome c oxidase, subunit III
YE105_C1120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YE105_C1121	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YE105_C1123	COG2223	nitrite transmembrane transporter activity
YE105_C1124	COG3056	Lipoprotein
YE105_C1125	COG0271	Belongs to the BolA IbaG family
YE105_C1126	COG0544	peptidyl-prolyl cis-trans isomerase activity
YE105_C1127	COG0740	serine-type endopeptidase activity
YE105_C1128	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YE105_C1129	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YE105_C1130	COG0776	regulation of translation
YE105_C1131	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YE105_C1132	COG1555	photosystem II stabilization
YE105_C1133	COG0824	Thioesterase
YE105_C1134	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YE105_C1135	COG4533	DNA binding
YE105_C1136	COG0561	phosphatase activity
YE105_C1138	COG1522	sequence-specific DNA binding
YE105_C1139	COG1132	(ABC) transporter
YE105_C1140	COG1132	(ABC) transporter
YE105_C1141	COG0347	Belongs to the P(II) protein family
YE105_C1142	COG0004	ammonium transporteR
YE105_C1143	COG1946	Acyl-CoA thioesterase
YE105_C1144	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YE105_C1145	COG3695	enzyme binding
YE105_C1151	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_C1152	COG0803	Belongs to the bacterial solute-binding protein 9 family
YE105_C1153	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YE105_C1154	COG0254	rRNA binding
YE105_C1157	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YE105_C1158	COG3457	Alanine racemase
YE105_C1160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_C1161	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C1162	COG1309	transcriptional regulator
YE105_C1163	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YE105_C1164	COG3264	Mechanosensitive ion channel
YE105_C1164	COG1196	nuclear chromosome segregation
YE105_C1167	COG2832	Protein of unknown function (DUF454)
YE105_C1168	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YE105_C1170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YE105_C1171	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YE105_C1172	COG0326	Molecular chaperone. Has ATPase activity
YE105_C1173	COG0563	adenylate kinase activity
YE105_C1174	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YE105_C1175	COG2244	polysaccharide biosynthetic process
YE105_C1176	COG1216	Glycosyl transferase, family 2
YE105_C1176	COG1442	glycosyl transferase family 8
YE105_C1177	COG1215	transferase activity, transferring glycosyl groups
YE105_C1178	COG0438	transferase activity, transferring glycosyl groups
YE105_C1179	COG0438	transferase activity, transferring glycosyl groups
YE105_C1180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YE105_C1184	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_C1185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YE105_C1185	COG4651	solute:proton antiporter activity
YE105_C1186	COG2223	nitrite transmembrane transporter activity
YE105_C1187	COG0737	Belongs to the 5'-nucleotidase family
YE105_C1188	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YE105_C1189	COG3735	TraB family
YE105_C1190	COG2217	Heavy metal translocating P-type atpase
YE105_C1191	COG0789	Transcriptional regulator
YE105_C1192	COG1585	Membrane protein implicated in regulation of membrane protease activity
YE105_C1193	COG0330	HflC and HflK could
YE105_C1194	COG3118	belongs to the thioredoxin family
YE105_C1195	COG0300	oxidoreductase activity
YE105_C1196	COG2755	lipolytic protein G-D-S-L family
YE105_C1197	COG4181	ATPase activity
YE105_C1198	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YE105_C1199	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YE105_C1200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YE105_C1201	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YE105_C1202	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YE105_C1203	COG0215	cysteine-tRNA ligase activity
YE105_C1204	COG2501	S4 domain
YE105_C1205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YE105_C1206	COG0582	viral genome integration into host DNA
YE105_C1214	COG2850	peptidyl-arginine hydroxylation
YE105_C1215	COG2986	histidine ammonia-lyase
YE105_C1218	COG5265	(ABC) transporter
YE105_C1221	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YE105_C1223	COG2197	response regulator
YE105_C1224	COG1278	Cold shock
YE105_C1225	COG1278	Cold shock
YE105_C1226	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YE105_C1227	COG3706	GGDEF domain
YE105_C1228	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YE105_C1229	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YE105_C1230	COG0321	lipoyl(octanoyl) transferase activity
YE105_C1231	COG2921	Belongs to the UPF0250 family
YE105_C1232	COG1686	Belongs to the peptidase S11 family
YE105_C1233	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YE105_C1234	COG0772	Belongs to the SEDS family
YE105_C1235	COG0768	penicillin binding
YE105_C1237	COG0799	negative regulation of ribosome biogenesis
YE105_C1238	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YE105_C1239	COG1466	dna polymerase III delta subunit
YE105_C1240	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
YE105_C1241	COG0495	leucyl-tRNA aminoacylation
YE105_C1242	COG2888	peptidyl-tyrosine sulfation
YE105_C1243	COG1126	abc transporter atp-binding protein
YE105_C1244	COG0765	amino acid transport
YE105_C1245	COG0765	amino acid transport
YE105_C1248	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YE105_C1249	COG4535	Mg2 and Co2 transporter CorC
YE105_C1250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YE105_C1251	COG1702	phosphate starvation-inducible protein PhoH
YE105_C1252	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YE105_C1253	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YE105_C1254	COG0367	asparagine synthase
YE105_C1255	COG0647	UMP catabolic process
YE105_C1256	COG1846	Transcriptional regulator
YE105_C1256	COG1940	carbohydrate kinase activity
YE105_C1257	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YE105_C1258	COG0363	glucosamine-6-phosphate deaminase activity
YE105_C1259	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C1259	COG1263	PTS System
YE105_C1259	COG2190	(PTS) system
YE105_C1260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YE105_C1263	COG0735	belongs to the Fur family
YE105_C1265	COG0840	transmembrane signaling receptor activity
YE105_C1267	COG0596	Alpha beta hydrolase
YE105_C1268	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YE105_C1269	COG0033	Phosphoglucomutase
YE105_C1272	COG0745	RESPONSE REGULATOR receiver
YE105_C1273	COG2205	protein histidine kinase activity
YE105_C1274	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YE105_C1275	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YE105_C1276	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YE105_C1279	COG2994	toxin metabolic process
YE105_C1280	COG3064	Membrane
YE105_C1280	COG1073	alpha beta
YE105_C1280	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YE105_C1281	COG3272	Protein of unknown function (DUF1722)
YE105_C1283	COG5212	phosphodiesterase
YE105_C1284	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YE105_C1285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YE105_C1286	COG1984	allophanate hydrolase subunit 2
YE105_C1287	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YE105_C1290	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YE105_C1292	COG2009	succinate dehydrogenase
YE105_C1293	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YE105_C1294	COG1053	succinate dehydrogenase
YE105_C1296	COG0567	Dehydrogenase, E1 component
YE105_C1297	COG0508	dehydrogenase complex catalyzes the overall conversion of
YE105_C1298	COG0045	succinate-CoA ligase (ADP-forming) activity
YE105_C1299	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YE105_C1300	COG1271	oxidase subunit
YE105_C1301	COG1294	oxidase, subunit
YE105_C1302	COG3790	cyd operon protein YbgE
YE105_C1303	COG0824	Thioesterase
YE105_C1304	COG0811	peptide transport
YE105_C1305	COG0848	biopolymer transport protein
YE105_C1306	COG3064	Membrane
YE105_C1306	COG3064	Membrane
YE105_C1307	COG0823	Involved in the tonB-independent uptake of proteins
YE105_C1308	COG2885	chlorophyll binding
YE105_C1309	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YE105_C1310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YE105_C1312	COG1230	cation diffusion facilitator family transporter
YE105_C1313	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YE105_C1314	COG0588	phosphoglycerate mutase activity
YE105_C1320	COG2017	converts alpha-aldose to the beta-anomer
YE105_C1321	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
YE105_C1322	COG1085	galactose-1-phosphate uridylyltransferase
YE105_C1323	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YE105_C1325	COG1119	ATPase activity
YE105_C1326	COG2005	Transcriptional regulator
YE105_C1326	COG3585	molybdate ion transport
YE105_C1328	COG0725	ABC transporter, periplasmic molybdate-binding protein
YE105_C1329	COG0582	viral genome integration into host DNA
YE105_C1365	COG3772	lysozyme
YE105_C1367	COG4149	molybdate abc transporter
YE105_C1369	COG0561	phosphatase activity
YE105_C1370	COG2706	6-phosphogluconolactonase activity
YE105_C1372	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YE105_C1373	COG0156	8-amino-7-oxononanoate synthase activity
YE105_C1374	COG2226	methyltransferase
YE105_C1375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YE105_C1377	COG0556	nucleotide-excision repair
YE105_C1378	COG4628	conserved protein (DUF2132)
YE105_C1379	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YE105_C1380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YE105_C1381	COG0315	cyclic pyranopterin monophosphate synthase activity
YE105_C1382	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YE105_C1383	COG0314	molybdopterin synthase activity
YE105_C1384	COG0670	Belongs to the BI1 family
YE105_C1385	COG0842	Transport permease protein
YE105_C1386	COG0842	Transport permease protein
YE105_C1387	COG1131	(ABC) transporter
YE105_C1388	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C1389	COG1309	transcriptional regulator
YE105_C1390	COG0513	Belongs to the DEAD box helicase family
YE105_C1391	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YE105_C1393	COG2239	Acts as a magnesium transporter
YE105_C1394	COG1686	Belongs to the peptidase S11 family
YE105_C1395	COG0277	FAD linked oxidase domain protein
YE105_C1397	COG1403	HNH endonuclease
YE105_C1399	COG2261	transglycosylase associated protein
YE105_C1401	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YE105_C1404	COG4807	Protein conserved in bacteria
YE105_C1408	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YE105_C1410	COG2897	thiosulfate sulfurtransferase activity
YE105_C1413	COG1732	Glycine betaine
YE105_C1414	COG1174	glycine betaine transport
YE105_C1415	COG1125	glycine betaine transport
YE105_C1416	COG1174	glycine betaine transport
YE105_C1418	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C1419	COG0583	DNA-binding transcription factor activity
YE105_C1421	COG0697	spore germination
YE105_C1425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YE105_C1426	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YE105_C1430	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
YE105_C1432	COG1126	abc transporter atp-binding protein
YE105_C1433	COG0765	amino acid transport
YE105_C1434	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_C1436	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YE105_C1437	COG0783	Belongs to the Dps family
YE105_C1438	COG4106	trans-aconitate 2-methyltransferase activity
YE105_C1441	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
YE105_C1445	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YE105_C1449	COG0488	(ABC) transporter
YE105_C1450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YE105_C1451	COG0303	'Molybdopterin
YE105_C1454	COG0577	efflux transmembrane transporter activity
YE105_C1454	COG1136	(ABC) transporter
YE105_C1460	COG0583	DNA-binding transcription factor activity
YE105_C1461	COG0477	Major facilitator Superfamily
YE105_C1462	COG0302	gtp cyclohydrolase
YE105_C1463	COG2311	Membrane
YE105_C1468	COG3604	Transcriptional regulator
YE105_C1469	COG3383	formate dehydrogenase (NAD+) activity
YE105_C1470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YE105_C1471	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YE105_C1473	COG3260	NADH ubiquinone oxidoreductase 20
YE105_C1474	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_C1475	COG3261	NADH dehydrogenase
YE105_C1475	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
YE105_C1476	COG0651	ATP synthesis coupled electron transport
YE105_C1477	COG4237	Hydrogenase 4 membrane
YE105_C1478	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YE105_C1479	COG0650	Formate hydrogenlyase subunit 4
YE105_C1480	COG0651	ATP synthesis coupled electron transport
YE105_C1481	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YE105_C1482	COG0375	protein maturation
YE105_C1483	COG0298	carbon dioxide binding
YE105_C1484	COG2949	membrane
YE105_C1485	COG0281	malic enzyme
YE105_C1487	COG1346	cytolysis
YE105_C1488	COG1380	Effector of murein hydrolase LrgA
YE105_C1489	COG2814	Major facilitator Superfamily
YE105_C1493	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YE105_C1493	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YE105_C1494	COG0489	protein tyrosine kinase activity
YE105_C1495	COG0572	uridine kinase
YE105_C1497	COG2982	Protein involved in outer membrane biogenesis
YE105_C1498	COG3069	C4-dicarboxylate transmembrane transporter activity
YE105_C1499	COG1253	flavin adenine dinucleotide binding
YE105_C1502	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YE105_C1503	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YE105_C1504	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YE105_C1505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YE105_C1510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YE105_C1512	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
YE105_C1513	COG0140	phosphoribosyl-ATP diphosphatase activity
YE105_C1513	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YE105_C1514	COG0107	imidazoleglycerol-phosphate synthase activity
YE105_C1515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YE105_C1516	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YE105_C1517	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YE105_C1517	COG0131	Imidazoleglycerol-phosphate dehydratase
YE105_C1518	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YE105_C1520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YE105_C1521	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_C1523	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C1524	COG1129	ABC transporter
YE105_C1526	COG0531	amino acid
YE105_C1527	COG2925	Exonuclease
YE105_C1528	COG1022	Amp-dependent synthetase and ligase
YE105_C1528	COG3320	Male sterility
YE105_C1529	COG1289	transmembrane transporter activity
YE105_C1530	COG2926	Belongs to the UPF0265 family
YE105_C1532	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C1534	COG1879	ABC-type sugar transport system periplasmic component
YE105_C1536	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YE105_C1538	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YE105_C1540	COG4810	utilization protein
YE105_C1542	COG4656	Part of a membrane complex involved in electron transport
YE105_C1544	COG1012	belongs to the aldehyde dehydrogenase family
YE105_C1550	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
YE105_C1557	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
YE105_C1561	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YE105_C1563	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
YE105_C1564	COG2241	protein methyltransferase activity
YE105_C1566	COG2875	Belongs to the precorrin methyltransferase family
YE105_C1576	COG1492	cobalamin metabolic process
YE105_C1580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YE105_C1581	COG2211	Major facilitator Superfamily
YE105_C1593	COG3121	Chaperone
YE105_C1594	COG3188	usher protein
YE105_C1603	COG3501	Rhs element vgr protein
YE105_C1608	COG0137	argininosuccinate synthase activity
YE105_C1609	COG0534	Mate efflux family protein
YE105_C1611	COG0352	thiamine-phosphate diphosphorylase activity
YE105_C1612	COG0561	phosphatase activity
YE105_C1613	COG1349	DNA-binding transcription factor activity
YE105_C1615	COG0784	Response regulator, receiver
YE105_C1615	COG0835	chemotaxis
YE105_C1620	COG3842	ATPase activity
YE105_C1622	COG1840	ABC-type Fe3 transport system, periplasmic component
YE105_C1623	COG2271	Major facilitator Superfamily
YE105_C1626	COG4565	transcriptional regulatory protein
YE105_C1627	COG3290	protein histidine kinase activity
YE105_C1628	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
YE105_C1629	COG3052	prosthetic group binding
YE105_C1630	COG2301	Belongs to the HpcH HpaI aldolase family
YE105_C1631	COG3051	citrate lyase alpha subunit
YE105_C1632	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
YE105_C1632	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
YE105_C1634	COG0471	metal ion transport
YE105_C1637	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YE105_C1641	COG2814	Major facilitator Superfamily
YE105_C1642	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C1642	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C1643	COG3122	Protein conserved in bacteria
YE105_C1646	COG3121	Chaperone
YE105_C1651	COG2205	protein histidine kinase activity
YE105_C1651	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_C1653	COG3228	Belongs to the MtfA family
YE105_C1655	COG1070	Carbohydrate kinase
YE105_C1660	COG3121	Chaperone
YE105_C1667	COG3321	synthase
YE105_C1667	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C1667	COG0604	alcohol dehydrogenase
YE105_C1668	COG3250	beta-galactosidase activity
YE105_C1669	COG1609	Transcriptional regulator
YE105_C1670	COG1278	Cold shock
YE105_C1672	COG0840	transmembrane signaling receptor activity
YE105_C1673	COG1285	pathogenesis
YE105_C1675	COG2130	NADP-dependent
YE105_C1676	COG0589	response to stress
YE105_C1680	COG1360	Flagellar Motor Protein
YE105_C1681	COG0643	Histidine kinase
YE105_C1681	COG2198	Histidine kinase
YE105_C1682	COG0835	chemotaxis
YE105_C1683	COG0840	transmembrane signaling receptor activity
YE105_C1684	COG0840	transmembrane signaling receptor activity
YE105_C1685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YE105_C1687	COG0745	RESPONSE REGULATOR receiver
YE105_C1688	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YE105_C1690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YE105_C1691	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YE105_C1694	COG3418	PFAM FlgN family protein
YE105_C1695	COG2747	anti-sigma28 factor FlgM
YE105_C1697	COG1815	bacterial-type flagellum-dependent cell motility
YE105_C1698	COG1558	bacterial-type flagellum-dependent cell motility
YE105_C1699	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YE105_C1700	COG1749	Flagellar hook protein flgE
YE105_C1702	COG4786	Flagellar basal body rod
YE105_C1706	COG1256	bacterial-type flagellum assembly
YE105_C1710	COG1338	Plays a role in the flagellum-specific transport system
YE105_C1714	COG1580	Controls the rotational direction of flagella during chemotaxis
YE105_C1716	COG2882	bacterial-type flagellum organization
YE105_C1718	COG1317	bacterial-type flagellum organization
YE105_C1719	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YE105_C1721	COG1677	Flagellar hook-basal body complex protein FliE
YE105_C1726	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YE105_C1727	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YE105_C1736	COG1191	sigma factor activity
YE105_C1738	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YE105_C1744	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YE105_C1744	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YE105_C1744	COG0506	proline dehydrogenase activity
YE105_C1747	COG3157	Type VI secretion system effector, Hcp
YE105_C1751	COG0655	NAD(P)H dehydrogenase (quinone) activity
YE105_C1753	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
YE105_C1754	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YE105_C1755	COG0778	Nitroreductase
YE105_C1756	COG2267	carboxylic ester hydrolase activity
YE105_C1757	COG0251	oxidation-reduction process
YE105_C1758	COG1335	isochorismatase
YE105_C1759	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YE105_C1760	COG1309	transcriptional regulator
YE105_C1761	COG1113	amino acid transport
YE105_C1762	COG2963	transposase activity
YE105_C1764	COG2226	methyltransferase
YE105_C1767	COG0366	Alpha amylase catalytic
YE105_C1769	COG3136	membrane protein required for alginate biosynthesis
YE105_C1771	COG2197	response regulator
YE105_C1772	COG0322	excinuclease ABC activity
YE105_C1773	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YE105_C1787	COG3077	Addiction module antitoxin, RelB DinJ family
YE105_C1788	COG3041	Addiction module toxin RelE StbE family
YE105_C1804	COG2801	Transposase and inactivated derivatives
YE105_C1805	COG2963	transposase activity
YE105_C1807	COG3328	transposase activity
YE105_C1816	COG3772	lysozyme
YE105_C1817	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YE105_C1818	COG2979	Protein of unknown function (DUF533)
YE105_C1821	COG0012	GTP binding
YE105_C1823	COG0193	aminoacyl-tRNA hydrolase activity
YE105_C1825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YE105_C1827	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
YE105_C1828	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YE105_C1829	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YE105_C1830	COG2890	protein-(glutamine-N5) methyltransferase activity
YE105_C1831	COG3094	Invasion gene expression up-regulator, SirB
YE105_C1832	COG2912	Transglutaminase-like superfamily
YE105_C1833	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YE105_C1834	COG0659	secondary active sulfate transmembrane transporter activity
YE105_C1835	COG3706	GGDEF domain
YE105_C1837	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YE105_C1838	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
YE105_C1839	COG3381	protein complex oligomerization
YE105_C1841	COG0477	Major facilitator Superfamily
YE105_C1844	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YE105_C1845	COG0728	peptidoglycan biosynthetic process
YE105_C1846	COG0387	Pfam Sodium calcium exchanger
YE105_C1848	COG0583	DNA-binding transcription factor activity
YE105_C1849	COG3850	Histidine kinase
YE105_C1850	COG1294	oxidase, subunit
YE105_C1851	COG1271	oxidase subunit
YE105_C1852	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_C1853	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YE105_C1854	COG3138	arginine N-succinyltransferase
YE105_C1856	COG3724	N-succinylarginine dihydrolase activity
YE105_C1857	COG2988	succinylglutamate desuccinylase activity
YE105_C1861	COG1228	amidohydrolase
YE105_C1863	COG0402	S-adenosylhomocysteine deaminase activity
YE105_C1865	COG3443	Belongs to the bacterial solute-binding protein 9 family
YE105_C1869	COG4942	peptidase
YE105_C1871	COG2222	sugar isomerase
YE105_C1872	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C1873	COG3716	PTS system mannose fructose sorbose family IID component
YE105_C1875	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C1877	COG1349	DNA-binding transcription factor activity
YE105_C1881	COG1187	pseudouridine synthase activity
YE105_C1882	COG0786	glutamate:sodium symporter activity
YE105_C1887	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YE105_C1888	COG2226	methyltransferase
YE105_C1889	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YE105_C1890	COG1801	Protein of unknown function DUF72
YE105_C1891	COG1335	isochorismatase
YE105_C1892	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YE105_C1893	COG0494	nUDIX hydrolase
YE105_C1894	COG0217	transcriptional regulatory protein
YE105_C1895	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YE105_C1896	COG0632	four-way junction helicase activity
YE105_C1897	COG2255	four-way junction helicase activity
YE105_C1898	COG3104	oligopeptide transport
YE105_C1899	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_C1900	COG1121	(ABC) transporter
YE105_C1901	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YE105_C1902	COG0739	heme binding
YE105_C1903	COG1560	Kdo2-lipid A biosynthetic process
YE105_C1905	COG3328	transposase activity
YE105_C1906	COG0469	pyruvate kinase activity
YE105_C1907	COG1737	Transcriptional regulator
YE105_C1908	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YE105_C1909	COG0800	Aldolase
YE105_C1910	COG2076	Multidrug Resistance protein
YE105_C1911	COG2076	Multidrug Resistance protein
YE105_C1912	COG0251	oxidation-reduction process
YE105_C1913	COG1199	ATP-dependent helicase activity
YE105_C1915	COG3065	identical protein binding
YE105_C1916	COG0318	PFAM AMP-dependent synthetase and ligase
YE105_C1917	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YE105_C1918	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YE105_C1919	COG2894	cell division
YE105_C1920	COG0850	regulation of cytokinetic process
YE105_C1922	COG3100	YcgL domain-containing protein
YE105_C1923	COG2951	lytic endotransglycosylase activity
YE105_C1924	COG0179	Fumarylacetoacetate (FAA) hydrolase
YE105_C1925	COG2983	Belongs to the UPF0260 family
YE105_C1932	COG0668	transmembrane transport
YE105_C1933	COG0625	glutathione transferase activity
YE105_C1939	COG4251	negative regulation of phosphorylation
YE105_C1939	COG5001	Diguanylate cyclase
YE105_C1939	COG2203	Gaf domain
YE105_C1939	COG3706	GGDEF domain
YE105_C1945	COG2814	Major facilitator Superfamily
YE105_C1947	COG3008	intermembrane lipid transfer
YE105_C1948	COG2995	paraquat-inducible protein a
YE105_C1949	COG1956	GAF domain-containing protein
YE105_C1951	COG0793	Belongs to the peptidase S41A family
YE105_C1952	COG0501	Belongs to the peptidase M48B family
YE105_C1954	COG2814	Major facilitator Superfamily
YE105_C1955	COG0823	Involved in the tonB-independent uptake of proteins
YE105_C1957	COG3023	N-Acetylmuramoyl-L-alanine amidase
YE105_C1959	COG1988	membrane-bound metal-dependent
YE105_C1960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YE105_C1961	COG1653	transport
YE105_C1962	COG3842	ATPase activity
YE105_C1963	COG0395	ABC-type sugar transport system, permease component
YE105_C1964	COG1175	transmembrane transport
YE105_C1967	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C1968	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
YE105_C1969	COG1917	Cupin 2, conserved barrel domain protein
YE105_C1970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_C1972	COG0583	DNA-binding transcription factor activity
YE105_C1973	COG0427	acetyl-CoA hydrolase
YE105_C1974	COG1024	Enoyl-CoA hydratase
YE105_C1975	COG1703	isobutyryl-CoA mutase activity
YE105_C1976	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YE105_C1976	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YE105_C1978	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_C1979	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_C1980	COG1121	(ABC) transporter
YE105_C1981	COG0803	Belongs to the bacterial solute-binding protein 9 family
YE105_C1986	COG1811	Na channel or pump
YE105_C1989	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YE105_C1990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
YE105_C1991	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YE105_C1992	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YE105_C1993	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YE105_C1995	COG0776	regulation of translation
YE105_C1996	COG2314	TM2 domain
YE105_C1998	COG4139	cobalamin transport
YE105_C1999	COG0386	Belongs to the glutathione peroxidase family
YE105_C2000	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YE105_C2001	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YE105_C2002	COG0463	Glycosyl transferase, family 2
YE105_C2003	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_C2003	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YE105_C2004	COG0726	polysaccharide deacetylase
YE105_C2005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YE105_C2006	COG2076	Multidrug Resistance protein
YE105_C2007	COG2076	Multidrug Resistance protein
YE105_C2008	COG0791	NLP P60 protein
YE105_C2009	COG0095	Lipoate-protein ligase
YE105_C2011	COG4558	Periplasmic binding protein
YE105_C2012	COG3720	iron ion transport
YE105_C2016	COG0574	Belongs to the PEP-utilizing enzyme family
YE105_C2016	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YE105_C2017	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YE105_C2018	COG0628	permease
YE105_C2019	COG0277	FAD linked oxidase domain protein
YE105_C2019	COG0247	lactate metabolic process
YE105_C2020	COG2050	protein possibly involved in aromatic compounds catabolism
YE105_C2021	COG0316	Belongs to the HesB IscA family
YE105_C2022	COG0719	Fe-S assembly protein
YE105_C2023	COG0396	ATPase activity
YE105_C2024	COG0719	Fe-S assembly protein
YE105_C2026	COG2166	iron-sulfur cluster assembly
YE105_C2027	COG1376	ErfK ybiS ycfS ynhG family protein
YE105_C2027	COG1388	LysM domain
YE105_C2029	COG0534	Mate efflux family protein
YE105_C2030	COG0307	riboflavin synthase, alpha
YE105_C2031	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YE105_C2032	COG2814	Major facilitator Superfamily
YE105_C2033	COG0583	DNA-binding transcription factor activity
YE105_C2034	COG1609	Transcriptional regulator
YE105_C2035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YE105_C2036	COG0791	NLP P60 protein
YE105_C2037	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YE105_C2038	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YE105_C2039	COG0346	lactoylglutathione lyase activity
YE105_C2040	COG1902	pentaerythritol trinitrate reductase activity
YE105_C2041	COG1309	transcriptional regulator
YE105_C2042	COG2194	sulfuric ester hydrolase activity
YE105_C2043	COG3313	Fe-S protein
YE105_C2044	COG4989	oxidoreductase activity
YE105_C2045	COG1289	transmembrane transporter activity
YE105_C2046	COG1566	PFAM secretion protein HlyD family protein
YE105_C2048	COG1846	Transcriptional regulator
YE105_C2049	COG3133	Outer membrane lipoprotein
YE105_C2050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YE105_C2051	COG3895	Periplasmic Protein
YE105_C2052	COG0259	pyridoxamine-phosphate oxidase activity
YE105_C2053	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YE105_C2055	COG0625	glutathione transferase activity
YE105_C2059	COG3104	oligopeptide transport
YE105_C2062	COG4172	Belongs to the ABC transporter superfamily
YE105_C2064	COG4171	peptide transport system, permease
YE105_C2065	COG4168	peptide transport system, permease
YE105_C2066	COG4166	transmembrane transport
YE105_C2069	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YE105_C2070	COG1842	Phage shock protein A
YE105_C2072	COG1983	PspC domain protein
YE105_C2074	COG3106	COG3106 Predicted ATPase
YE105_C2075	COG3768	UPF0283 membrane protein
YE105_C2079	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YE105_C2080	COG4948	Mandelate Racemase Muconate Lactonizing
YE105_C2081	COG2866	Carboxypeptidase
YE105_C2082	COG4166	transmembrane transport
YE105_C2083	COG0598	Magnesium transport protein CorA
YE105_C2084	COG0037	tRNA processing
YE105_C2085	COG0823	Involved in the tonB-independent uptake of proteins
YE105_C2086	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_C2086	COG0674	pyruvate-flavodoxin oxidoreductase activity
YE105_C2086	COG1013	pyruvate-flavodoxin oxidoreductase activity
YE105_C2086	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YE105_C2088	COG1285	pathogenesis
YE105_C2089	COG3042	response to heat
YE105_C2090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YE105_C2091	COG2911	Protein conserved in bacteria
YE105_C2093	COG3784	Protein of unknown function (DUF1318)
YE105_C2094	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YE105_C2095	COG1643	Atp-dependent helicase
YE105_C2098	COG3591	Belongs to the peptidase S1B family
YE105_C2100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YE105_C2101	COG2205	protein histidine kinase activity
YE105_C2102	COG0745	RESPONSE REGULATOR receiver
YE105_C2104	COG0531	amino acid
YE105_C2106	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YE105_C2107	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YE105_C2108	COG0589	response to stress
YE105_C2109	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YE105_C2110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YE105_C2112	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
YE105_C2113	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C2115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_C2116	COG0738	Major facilitator superfamily
YE105_C2118	COG1011	Hydrolase
YE105_C2119	COG0440	acetolactate synthase activity
YE105_C2120	COG0028	Belongs to the TPP enzyme family
YE105_C2122	COG3023	N-Acetylmuramoyl-L-alanine amidase
YE105_C2126	COG2271	Major facilitator Superfamily
YE105_C2127	COG0483	inositol monophosphate 1-phosphatase activity
YE105_C2129	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YE105_C2138	COG4215	(ABC) transporter
YE105_C2140	COG1522	sequence-specific DNA binding
YE105_C2145	COG0625	glutathione transferase activity
YE105_C2152	COG1450	Type ii and iii secretion system protein
YE105_C2165	COG1450	Type ii and iii secretion system protein
YE105_C2178	COG4221	oxidoreductase activity
YE105_C2179	COG1742	UPF0060 membrane protein
YE105_C2185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YE105_C2186	COG1940	carbohydrate kinase activity
YE105_C2187	COG0583	DNA-binding transcription factor activity
YE105_C2188	COG2814	Major facilitator Superfamily
YE105_C2192	COG0114	fumarate hydratase activity
YE105_C2194	COG5339	Protein conserved in bacteria
YE105_C2196	COG1609	Transcriptional regulator
YE105_C2197	COG1263	PTS System
YE105_C2197	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C2198	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YE105_C2199	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YE105_C2200	COG0385	Bile acid
YE105_C2201	COG0673	inositol 2-dehydrogenase activity
YE105_C2203	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_C2205	COG1879	ABC-type sugar transport system periplasmic component
YE105_C2207	COG2160	L-arabinose isomerase activity
YE105_C2208	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YE105_C2209	COG2274	protein secretion by the type I secretion system
YE105_C2211	COG2759	Belongs to the formate--tetrahydrofolate ligase family
YE105_C2213	COG4657	Part of a membrane complex involved in electron transport
YE105_C2215	COG4656	Part of a membrane complex involved in electron transport
YE105_C2219	COG3708	Transcriptional regulator
YE105_C2219	COG2207	Transcriptional regulator
YE105_C2220	COG4658	electron transport chain
YE105_C2221	COG4659	FMN binding
YE105_C2223	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YE105_C2224	COG0243	molybdopterin cofactor binding
YE105_C2225	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YE105_C2226	COG1966	Carbon starvation protein
YE105_C2227	COG2879	small protein
YE105_C2228	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YE105_C2229	COG1349	DNA-binding transcription factor activity
YE105_C2231	COG0235	Class ii aldolase
YE105_C2233	COG0023	Translation Initiation Factor
YE105_C2234	COG0284	orotidine-5'-phosphate decarboxylase activity
YE105_C2236	COG3135	benzoate transporter
YE105_C2237	COG1396	sequence-specific DNA binding
YE105_C2239	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YE105_C2240	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YE105_C2241	COG0671	phosphoesterase, PA-phosphatase related
YE105_C2242	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YE105_C2245	COG0583	DNA-binding transcription factor activity
YE105_C2246	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YE105_C2248	COG0616	signal peptide processing
YE105_C2249	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C2250	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
YE105_C2252	COG1187	pseudouridine synthase activity
YE105_C2253	COG0009	L-threonylcarbamoyladenylate synthase
YE105_C2254	COG0613	PHP domain protein
YE105_C2256	COG0512	Glutamine amidotransferase of anthranilate synthase
YE105_C2258	COG0134	indole-3-glycerol-phosphate synthase activity
YE105_C2258	COG0135	phosphoribosylanthranilate isomerase activity
YE105_C2259	COG0133	tryptophan synthase activity
YE105_C2260	COG0159	tryptophan synthase activity
YE105_C2262	COG3047	cAMP biosynthetic process
YE105_C2266	COG2917	probably involved in intracellular septation
YE105_C2267	COG1607	acyl-coa hydrolase
YE105_C2268	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YE105_C2269	COG2350	Protein conserved in bacteria
YE105_C2272	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YE105_C2273	COG3099	Belongs to the UPF0263 family
YE105_C2275	COG0444	Belongs to the ABC transporter superfamily
YE105_C2276	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YE105_C2280	COG2095	MarC family integral membrane protein
YE105_C2281	COG1454	alcohol dehydrogenase
YE105_C2281	COG1012	belongs to the aldehyde dehydrogenase family
YE105_C2283	COG1435	thymidine kinase activity
YE105_C2284	COG2916	Histone family protein nucleoid-structuring protein H-NS
YE105_C2286	COG0745	RESPONSE REGULATOR receiver
YE105_C2287	COG1752	Esterase of the alpha-beta hydrolase superfamily
YE105_C2289	COG3012	SEC-C Motif Domain Protein
YE105_C2290	COG0788	formyltetrahydrofolate deformylase activity
YE105_C2291	COG0583	DNA-binding transcription factor activity
YE105_C2292	COG0708	Exodeoxyribonuclease III
YE105_C2293	COG0494	nUDIX hydrolase
YE105_C2295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YE105_C2297	COG0778	Nitroreductase
YE105_C2298	COG0616	signal peptide processing
YE105_C2299	COG0252	asparaginase activity
YE105_C2300	COG1335	isochorismatase
YE105_C2302	COG3139	Protein of unknown function (DUF1315)
YE105_C2303	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YE105_C2306	COG3713	MltA-interacting MipA family protein
YE105_C2307	COG2766	serine protein kinase
YE105_C2308	COG2718	Belongs to the UPF0229 family
YE105_C2311	COG0583	DNA-binding transcription factor activity
YE105_C2313	COG2199	diguanylate cyclase activity
YE105_C2313	COG2202	Pas domain
YE105_C2313	COG2200	EAL domain
YE105_C2314	COG2814	Major facilitator Superfamily
YE105_C2315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YE105_C2316	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YE105_C2317	COG2719	SpoVR family
YE105_C2318	COG2186	Transcriptional regulator
YE105_C2319	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YE105_C2320	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YE105_C2323	COG3142	Participates in the control of copper homeostasis
YE105_C2324	COG3102	Protein conserved in bacteria
YE105_C2325	COG0018	arginyl-trna synthetase
YE105_C2327	COG1702	phosphate starvation-inducible protein PhoH
YE105_C2330	COG3658	cytochrome
YE105_C2331	COG1215	transferase activity, transferring glycosyl groups
YE105_C2332	COG0726	polysaccharide deacetylase
YE105_C2332	COG1649	PFAM Uncharacterised BCR, COG1649
YE105_C2333	COG0457	Tetratricopeptide repeat
YE105_C2334	COG0006	proline dipeptidase activity
YE105_C2335	COG4114	ferric iron reductase
YE105_C2336	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YE105_C2341	COG1136	(ABC) transporter
YE105_C2341	COG0577	efflux transmembrane transporter activity
YE105_C2343	COG0577	efflux transmembrane transporter activity
YE105_C2343	COG1136	(ABC) transporter
YE105_C2346	COG0672	)-iron permease
YE105_C2349	COG2066	Belongs to the glutaminase family
YE105_C2350	COG3622	Belongs to the hyi family
YE105_C2351	COG0235	Class ii aldolase
YE105_C2352	COG3395	kinase activity
YE105_C2353	COG1349	DNA-binding transcription factor activity
YE105_C2354	COG3290	protein histidine kinase activity
YE105_C2355	COG4565	transcriptional regulatory protein
YE105_C2356	COG3493	citrate carrier protein
YE105_C2360	COG2223	nitrite transmembrane transporter activity
YE105_C2361	COG0561	phosphatase activity
YE105_C2364	COG0500	methyltransferase
YE105_C2365	COG3328	transposase activity
YE105_C2374	COG4974	Belongs to the 'phage' integrase family
YE105_C2376	COG1276	copper resistance
YE105_C2377	COG2372	response to copper ion
YE105_C2378	COG1528	Iron-storage protein
YE105_C2380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YE105_C2381	COG1770	oligopeptidase
YE105_C2384	COG3141	response to X-ray
YE105_C2385	COG0513	Belongs to the DEAD box helicase family
YE105_C2386	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
YE105_C2387	COG3140	Belongs to the UPF0181 family
YE105_C2389	COG0494	nUDIX hydrolase
YE105_C2390	COG1760	l-serine dehydratase
YE105_C2391	COG1253	flavin adenine dinucleotide binding
YE105_C2392	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C2392	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C2393	COG3715	PTS system
YE105_C2394	COG3716	PTS system mannose fructose sorbose family IID component
YE105_C2395	COG4811	Protein of unknown function (DUF986)
YE105_C2396	COG1971	Probably functions as a manganese efflux pump
YE105_C2398	COG5002	protein histidine kinase activity
YE105_C2398	COG3447	MASE1 domain protein
YE105_C2398	COG5001	Diguanylate cyclase
YE105_C2400	COG2226	methyltransferase
YE105_C2401	COG0768	penicillin binding
YE105_C2403	COG1278	Cold shock
YE105_C2406	COG1113	amino acid transport
YE105_C2412	COG2207	Transcriptional regulator
YE105_C2417	COG1132	(ABC) transporter
YE105_C2421	COG4251	negative regulation of phosphorylation
YE105_C2421	COG5001	Diguanylate cyclase
YE105_C2421	COG2203	Gaf domain
YE105_C2421	COG3706	GGDEF domain
YE105_C2423	COG3755	Protein conserved in bacteria
YE105_C2430	COG1733	regulation of RNA biosynthetic process
YE105_C2431	COG0702	epimerase
YE105_C2432	COG2873	o-acetylhomoserine
YE105_C2435	COG0840	transmembrane signaling receptor activity
YE105_C2445	COG0538	isocitrate dehydrogenase activity
YE105_C2446	COG1187	pseudouridine synthase activity
YE105_C2448	COG0482	sulfurtransferase activity
YE105_C2449	COG2915	High frequency lysogenization protein hflD homolog
YE105_C2450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YE105_C2452	COG0745	RESPONSE REGULATOR receiver
YE105_C2454	COG2850	peptidyl-arginine hydroxylation
YE105_C2456	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YE105_C2457	COG1940	carbohydrate kinase activity
YE105_C2458	COG4591	ABC-type transport system involved in lipoprotein release permease component
YE105_C2460	COG4591	ABC-type transport system involved in lipoprotein release permease component
YE105_C2461	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YE105_C2462	COG3134	Outer membrane lipoprotein
YE105_C2463	COG1252	NADH dehydrogenase
YE105_C2464	COG3150	esterase
YE105_C2465	COG1472	Belongs to the glycosyl hydrolase 3 family
YE105_C2467	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
YE105_C2468	COG5633	Lipoprotein
YE105_C2469	COG0537	adenosine 5'-monophosphoramidase activity
YE105_C2470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YE105_C2472	COG0641	radical SAM
YE105_C2476	COG1263	PTS System
YE105_C2476	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C2477	COG0084	hydrolase, TatD family'
YE105_C2478	COG0470	DNA polymerase III
YE105_C2479	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YE105_C2480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YE105_C2481	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YE105_C2482	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YE105_C2484	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C2485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YE105_C2486	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YE105_C2487	COG0416	fatty acid biosynthetic process
YE105_C2488	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YE105_C2489	COG1399	metal-binding, possibly nucleic acid-binding protein
YE105_C2491	COG0564	pseudouridine synthase activity
YE105_C2492	COG1530	ribonuclease E activity
YE105_C2493	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YE105_C2494	COG0418	dihydroorotase activity
YE105_C2499	COG0628	permease
YE105_C2507	COG1560	Kdo2-lipid A biosynthetic process
YE105_C2510	COG2259	Doxx family
YE105_C2511	COG3104	oligopeptide transport
YE105_C2514	COG5645	(Lipo)protein
YE105_C2515	COG2943	transferase activity, transferring hexosyl groups
YE105_C2516	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YE105_C2519	COG3263	regulation of cellular component size
YE105_C2520	COG3916	Acyl-homoserine-lactone synthase
YE105_C2521	COG2771	luxR family
YE105_C2522	COG4235	cytochrome complex assembly
YE105_C2523	COG3088	subunit of a heme lyase
YE105_C2524	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YE105_C2525	COG1138	Cytochrome C-type biogenesis protein
YE105_C2526	COG3301	Polysulphide reductase, NrfD
YE105_C2527	COG0437	4 iron, 4 sulfur cluster binding
YE105_C2528	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
YE105_C2531	COG2920	part of a sulfur-relay system
YE105_C2532	COG1254	Belongs to the acylphosphatase family
YE105_C2535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YE105_C2536	COG3785	DNA binding
YE105_C2537	COG1832	CoA-binding protein
YE105_C2538	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YE105_C2539	COG1803	Methylglyoxal synthase
YE105_C2540	COG0210	DNA helicase
YE105_C2541	COG3304	Inner membrane component domain
YE105_C2542	COG1289	transmembrane transporter activity
YE105_C2543	COG3070	regulator of competence-specific genes
YE105_C2544	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
YE105_C2545	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YE105_C2545	COG2885	chlorophyll binding
YE105_C2546	COG3120	sequence-specific DNA binding
YE105_C2547	COG1067	ATP-dependent peptidase activity
YE105_C2548	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YE105_C2551	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YE105_C2552	COG3009	Protein conserved in bacteria
YE105_C2553	COG3008	intermembrane lipid transfer
YE105_C2553	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YE105_C2554	COG2995	paraquat-inducible protein a
YE105_C2555	COG0488	(ABC) transporter
YE105_C2556	COG0116	Belongs to the methyltransferase superfamily
YE105_C2556	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YE105_C2557	COG3217	Mosc domain protein beta barrel domain protein
YE105_C2557	COG0633	Ferredoxin
YE105_C2559	COG0167	dihydroorotate dehydrogenase activity
YE105_C2560	COG0308	aminopeptidase N
YE105_C2561	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YE105_C2562	COG0017	Asparaginyl-tRNA synthetase
YE105_C2564	COG1448	Aminotransferase
YE105_C2565	COG2200	EAL domain
YE105_C2566	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YE105_C2567	COG3108	Peptidase M15
YE105_C2568	COG2989	Protein conserved in bacteria
YE105_C2569	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
YE105_C2570	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YE105_C2571	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YE105_C2572	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YE105_C2573	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YE105_C2574	COG3173	Aminoglycoside phosphotransferase
YE105_C2575	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
YE105_C2576	COG2835	tetraacyldisaccharide 4'-kinase activity
YE105_C2577	COG1278	Cold shock
YE105_C2578	COG1278	Cold shock
YE105_C2579	COG5383	Protein conserved in bacteria
YE105_C2580	COG1663	tetraacyldisaccharide 4'-kinase activity
YE105_C2582	COG0658	competence protein
YE105_C2582	COG2333	competence protein COMEC
YE105_C2583	COG0776	regulation of translation
YE105_C2584	COG0539	negative regulation of cytoplasmic translation
YE105_C2585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YE105_C2586	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YE105_C2587	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YE105_C2588	COG2323	membrane
YE105_C2589	COG0252	asparaginase activity
YE105_C2590	COG1944	ATP diphosphatase activity
YE105_C2591	COG2116	formate transmembrane transporter activity
YE105_C2592	COG1882	Formate acetyltransferase
YE105_C2593	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YE105_C2594	COG2814	Major facilitator Superfamily
YE105_C2595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YE105_C2596	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YE105_C2597	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
YE105_C2598	COG3107	peptidoglycan biosynthetic process
YE105_C2598	COG1674	ftsk spoiiie
YE105_C2599	COG1522	sequence-specific DNA binding
YE105_C2600	COG0492	ferredoxin-NADP+ reductase activity
YE105_C2602	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YE105_C2603	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YE105_C2604	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YE105_C2605	COG0542	response to heat
YE105_C2606	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YE105_C2607	COG1278	Cold shock
YE105_C2609	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C2610	COG2990	Protein conserved in bacteria
YE105_C2611	COG3593	DNA synthesis involved in DNA repair
YE105_C2612	COG2431	L-lysine efflux transmembrane transporter activity
YE105_C2613	COG1151	hydroxylamine reductase activity
YE105_C2614	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YE105_C2615	COG0028	Belongs to the TPP enzyme family
YE105_C2617	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YE105_C2618	COG0702	epimerase
YE105_C2619	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_C2621	COG1126	abc transporter atp-binding protein
YE105_C2622	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_C2623	COG4215	(ABC) transporter
YE105_C2624	COG4160	amino acid transport
YE105_C2626	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_C2627	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YE105_C2629	COG1177	transmembrane transport
YE105_C2630	COG1176	ABC-type spermidine putrescine transport system, permease component I
YE105_C2631	COG3842	ATPase activity
YE105_C2632	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YE105_C2635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YE105_C2636	COG2985	domain, Protein
YE105_C2636	COG0569	domain protein
YE105_C2638	COG0671	phosphoesterase, PA-phosphatase related
YE105_C2639	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YE105_C2640	COG1349	DNA-binding transcription factor activity
YE105_C2641	COG0814	amino acid
YE105_C2642	COG1760	l-serine dehydratase
YE105_C2643	COG1686	Belongs to the peptidase S11 family
YE105_C2645	COG0626	cystathionine gamma-synthase activity
YE105_C2646	COG2011	ABC-type metal ion transport system permease component
YE105_C2651	COG0625	glutathione transferase activity
YE105_C2652	COG4771	TonB-dependent receptor
YE105_C2654	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_C2655	COG0833	amino acid
YE105_C2656	COG0583	DNA-binding transcription factor activity
YE105_C2659	COG2855	membrane
YE105_C2660	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
YE105_C2665	COG3710	Transcriptional regulator
YE105_C2666	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YE105_C2666	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YE105_C2666	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YE105_C2667	COG1105	Belongs to the carbohydrate kinase PfkB family
YE105_C2670	COG3005	denitrification pathway
YE105_C2671	COG0243	molybdopterin cofactor binding
YE105_C2674	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YE105_C2675	COG1312	Catalyzes the dehydration of D-mannonate
YE105_C2677	COG0246	Mannitol dehydrogenase
YE105_C2678	COG2186	Transcriptional regulator
YE105_C2680	COG0523	cobalamin synthesis protein
YE105_C2681	COG0671	phosphoesterase, PA-phosphatase related
YE105_C2682	COG0791	NLP P60 protein
YE105_C2683	COG2200	EAL domain
YE105_C2684	COG4166	transmembrane transport
YE105_C2685	COG4174	ABC transporter (Permease)
YE105_C2686	COG4239	(ABC) transporter, permease
YE105_C2687	COG4172	Belongs to the ABC transporter superfamily
YE105_C2689	COG2814	Major facilitator Superfamily
YE105_C2690	COG1187	pseudouridine synthase activity
YE105_C2691	COG1061	Type III restriction enzyme res subunit
YE105_C2692	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YE105_C2693	COG3081	Nucleoid-associated protein
YE105_C2694	COG3082	Protein of unknown function (DUF1414)
YE105_C2698	COG2963	transposase activity
YE105_C2699	COG2801	Transposase and inactivated derivatives
YE105_C2703	COG3338	carbonate dehydratase activity
YE105_C2704	COG2723	6-phospho-beta-galactosidase activity
YE105_C2705	COG1263	PTS System
YE105_C2705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C2705	COG2190	(PTS) system
YE105_C2706	COG1737	Transcriptional regulator
YE105_C2718	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YE105_C2719	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YE105_C2720	COG2223	nitrite transmembrane transporter activity
YE105_C2721	COG0642	Histidine kinase
YE105_C2721	COG2198	Histidine kinase
YE105_C2722	COG2197	response regulator
YE105_C2723	COG2205	protein histidine kinase activity
YE105_C2723	COG0784	Response regulator, receiver
YE105_C2725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YE105_C2726	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YE105_C2728	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YE105_C2729	COG4574	serine-type endopeptidase inhibitor activity
YE105_C2734	COG0814	amino acid
YE105_C2738	COG1441	menaquinone biosynthetic process
YE105_C2739	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YE105_C2740	COG0596	Alpha beta hydrolase
YE105_C2741	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
YE105_C2742	COG1169	isochorismate synthase
YE105_C2743	COG3328	transposase activity
YE105_C2744	COG4575	ribosome binding
YE105_C2745	COG0129	dihydroxy-acid dehydratase activity
YE105_C2746	COG4702	Belongs to the UPF0303 family
YE105_C2748	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YE105_C2749	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C2750	COG3265	gluconokinase activity
YE105_C2755	COG1007	ATP synthesis coupled electron transport
YE105_C2756	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_C2757	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YE105_C2758	COG0713	ATP synthesis coupled electron transport
YE105_C2759	COG0839	Belongs to the complex I subunit 6 family
YE105_C2760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_C2761	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YE105_C2762	COG1034	ATP synthesis coupled electron transport
YE105_C2764	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
YE105_C2765	COG0649	NAD binding
YE105_C2765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_C2766	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_C2767	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_C2768	COG0583	DNA-binding transcription factor activity
YE105_C2769	COG0436	Aminotransferase
YE105_C2770	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
YE105_C2771	COG0471	metal ion transport
YE105_C2771	COG0490	domain, Protein
YE105_C2772	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_C2773	COG3013	Belongs to the UPF0304 family
YE105_C2774	COG3092	negative regulation of chromosome organization
YE105_C2776	COG0857	belongs to the CobB CobQ family
YE105_C2776	COG0280	phosphate acetyltransferase
YE105_C2777	COG1609	Transcriptional regulator
YE105_C2778	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C2780	COG3037	sugar-specific permease SgaT UlaA
YE105_C2781	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YE105_C2782	COG0622	Phosphoesterase
YE105_C2784	COG1090	epimerase
YE105_C2786	COG4598	ABC transporter
YE105_C2787	COG4160	amino acid transport
YE105_C2788	COG4215	(ABC) transporter
YE105_C2789	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_C2790	COG0163	prenyltransferase activity
YE105_C2791	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YE105_C2792	COG1286	toxin biosynthetic process
YE105_C2793	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YE105_C2794	COG0285	dihydrofolate synthase activity
YE105_C2795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YE105_C2796	COG0586	Pfam SNARE associated Golgi protein
YE105_C2798	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YE105_C2799	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YE105_C2801	COG0697	spore germination
YE105_C2802	COG0697	spore germination
YE105_C2803	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_C2804	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YE105_C2809	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YE105_C2811	COG1609	Transcriptional regulator
YE105_C2812	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_C2813	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_C2814	COG2723	6-phospho-beta-galactosidase activity
YE105_C2815	COG1447	Phosphotransferase system cellobiose-specific component IIA
YE105_C2817	COG1794	racemase activity, acting on amino acids and derivatives
YE105_C2818	COG3706	GGDEF domain
YE105_C2819	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YE105_C2820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YE105_C2820	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YE105_C2822	COG3101	peptidyl-lysine hydroxylation
YE105_C2823	COG0730	response to heat
YE105_C2824	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
YE105_C2825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YE105_C2826	COG2890	protein-(glutamine-N5) methyltransferase activity
YE105_C2827	COG2840	Smr protein MutS2
YE105_C2828	COG2062	phosphohistidine phosphatase, SixA
YE105_C2829	COG1024	Enoyl-CoA hydratase
YE105_C2829	COG1250	3-hydroxyacyl-CoA dehydrogenase
YE105_C2830	COG0183	Belongs to the thiolase family
YE105_C2831	COG3691	Protein conserved in bacteria
YE105_C2834	COG3088	subunit of a heme lyase
YE105_C2834	COG4235	cytochrome complex assembly
YE105_C2836	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YE105_C2837	COG1138	Cytochrome C-type biogenesis protein
YE105_C2838	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
YE105_C2839	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YE105_C2840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YE105_C2841	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YE105_C2843	COG2116	formate transmembrane transporter activity
YE105_C2844	COG0582	viral genome integration into host DNA
YE105_C2857	COG2824	Alkylphosphonate utilization operon protein PhnA
YE105_C2858	COG1695	Transcriptional regulator
YE105_C2860	COG2723	6-phospho-beta-galactosidase activity
YE105_C2861	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C2861	COG1263	PTS System
YE105_C2862	COG1609	Transcriptional regulator
YE105_C2863	COG2353	YceI-like domain
YE105_C2864	COG3038	cytochrome b561
YE105_C2867	COG1127	ABC transporter
YE105_C2868	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YE105_C2872	COG0531	amino acid
YE105_C2873	COG2951	lytic endotransglycosylase activity
YE105_C2877	COG1280	lysine exporter protein (LysE YggA)
YE105_C2879	COG1598	PFAM Uncharacterised protein family UPF0150
YE105_C2880	COG3038	cytochrome b561
YE105_C2881	COG0436	Aminotransferase
YE105_C2884	COG3275	phosphorelay sensor kinase activity
YE105_C2885	COG3279	Response regulator of the LytR AlgR family
YE105_C2886	COG2223	nitrite transmembrane transporter activity
YE105_C2887	COG0837	glucose binding
YE105_C2890	COG3961	Belongs to the TPP enzyme family
YE105_C2891	COG0667	Aldo Keto reductase
YE105_C2893	COG1914	H( )-stimulated, divalent metal cation uptake system
YE105_C2894	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YE105_C2895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YE105_C2898	COG3530	Putative quorum-sensing-regulated virulence factor
YE105_C2899	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YE105_C2902	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YE105_C2903	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C2904	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YE105_C2905	COG2190	(PTS) system
YE105_C2906	COG2205	protein histidine kinase activity
YE105_C2907	COG0745	RESPONSE REGULATOR receiver
YE105_C2908	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C2912	COG4208	sulfate ABC transporter
YE105_C2913	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YE105_C2914	COG4150	thiosulfate binding
YE105_C2916	COG1737	Transcriptional regulator
YE105_C2917	COG2731	YhcH YjgK YiaL family protein
YE105_C2920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YE105_C2922	COG2837	iron assimilation
YE105_C2924	COG3111	PFAM Bacterial OB fold (BOF) protein
YE105_C2925	COG0456	acetyltransferase
YE105_C2926	COG0408	coproporphyrinogen oxidase activity
YE105_C2927	COG1671	Belongs to the UPF0178 family
YE105_C2929	COG0280	phosphate acetyltransferase
YE105_C2929	COG0281	malic enzyme
YE105_C2930	COG0494	nUDIX hydrolase
YE105_C2931	COG3005	denitrification pathway
YE105_C2932	COG3043	anaerobic respiration
YE105_C2933	COG0243	molybdopterin cofactor binding
YE105_C2934	COG3062	negative regulation of establishment of protein localization
YE105_C2936	COG2197	response regulator
YE105_C2938	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_C2941	COG1393	Belongs to the ArsC family
YE105_C2942	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YE105_C2943	COG1876	peptidase activity
YE105_C2950	COG0400	carboxylic ester hydrolase activity
YE105_C2953	COG1444	tRNA N-acetyltransferase activity
YE105_C2954	COG2707	UPF0756 membrane protein
YE105_C2955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YE105_C2956	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YE105_C2957	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YE105_C2958	COG2716	regulation of RNA biosynthetic process
YE105_C2959	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YE105_C2960	COG0628	permease
YE105_C2961	COG4783	chaperone-mediated protein folding
YE105_C2962	COG1393	Belongs to the ArsC family
YE105_C2963	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YE105_C2964	COG2233	PERMEase
YE105_C2965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YE105_C2966	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YE105_C2967	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YE105_C2968	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YE105_C2972	COG0581	inorganic phosphate transmembrane transporter activity
YE105_C2973	COG0573	inorganic phosphate transmembrane transporter activity
YE105_C2974	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YE105_C2975	COG0248	Ppx GppA phosphatase
YE105_C2977	COG2239	Acts as a magnesium transporter
YE105_C2978	COG3447	MASE1 domain protein
YE105_C2978	COG5002	protein histidine kinase activity
YE105_C2978	COG5001	Diguanylate cyclase
YE105_C2979	COG0443	Heat shock 70 kDa protein
YE105_C2980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C2982	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_C2983	COG0477	Major facilitator Superfamily
YE105_C2984	COG2205	protein histidine kinase activity
YE105_C2985	COG0745	RESPONSE REGULATOR receiver
YE105_C2986	COG3422	double-strand break repair
YE105_C2988	COG1597	lipid kinase activity
YE105_C2989	COG3730	PTS system glucitol sorbitol-specific
YE105_C2992	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_C2993	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C2994	COG1349	DNA-binding transcription factor activity
YE105_C2998	COG0351	phosphomethylpyrimidine kinase
YE105_C3007	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YE105_C3007	COG0519	Catalyzes the synthesis of GMP from XMP
YE105_C3008	COG0516	GMP reductase activity
YE105_C3008	COG0517	IMP dehydrogenase activity
YE105_C3009	COG1570	exodeoxyribonuclease VII activity
YE105_C3010	COG1645	bacterial-type flagellum-dependent swarming motility
YE105_C3012	COG1160	GTP binding
YE105_C3013	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YE105_C3014	COG2976	Protein conserved in bacteria
YE105_C3015	COG0124	histidyl-tRNA synthetase
YE105_C3016	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YE105_C3017	COG1426	Protein conserved in bacteria
YE105_C3019	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YE105_C3022	COG4953	penicillin-binding protein 1C
YE105_C3023	COG2373	Large extracellular alpha-helical protein
YE105_C3026	COG3468	outer membrane autotransporter barrel domain protein
YE105_C3029	COG2975	iron-sulfur cluster assembly
YE105_C3030	COG0633	Ferredoxin
YE105_C3031	COG0443	Heat shock 70 kDa protein
YE105_C3032	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YE105_C3033	COG0316	Belongs to the HesB IscA family
YE105_C3034	COG0822	iron-sulfur transferase activity
YE105_C3036	COG1959	2 iron, 2 sulfur cluster binding
YE105_C3037	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
YE105_C3038	COG0483	inositol monophosphate 1-phosphatase activity
YE105_C3039	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YE105_C3040	COG3683	transport system, periplasmic component
YE105_C3041	COG3711	transcriptional antiterminator
YE105_C3042	COG2814	Major facilitator Superfamily
YE105_C3043	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YE105_C3044	COG1017	nitric oxide dioxygenase activity
YE105_C3044	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YE105_C3045	COG2188	Transcriptional regulator
YE105_C3047	COG3457	Alanine racemase
YE105_C3048	COG1735	metal-dependent hydrolase with the TIM-barrel fold
YE105_C3051	COG0347	Belongs to the P(II) protein family
YE105_C3052	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YE105_C3052	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YE105_C3053	COG2204	response regulator
YE105_C3054	COG3170	Tfp pilus assembly protein FimV
YE105_C3055	COG2205	protein histidine kinase activity
YE105_C3059	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YE105_C3060	COG0590	tRNA wobble adenosine to inosine editing
YE105_C3062	COG0560	Phosphoserine phosphatase
YE105_C3064	COG1737	Transcriptional regulator
YE105_C3065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YE105_C3066	COG2610	gluconate transmembrane transporter activity
YE105_C3067	COG0736	holo-[acyl-carrier-protein] synthase activity
YE105_C3068	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YE105_C3069	COG1381	Involved in DNA repair and RecF pathway recombination
YE105_C3070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YE105_C3071	COG0571	ribonuclease III activity
YE105_C3072	COG0681	Belongs to the peptidase S26 family
YE105_C3073	COG0481	GTPase activity
YE105_C3075	COG3086	response to oxidative stress
YE105_C3077	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YE105_C3079	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YE105_C3080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
YE105_C3081	COG0513	Belongs to the DEAD box helicase family
YE105_C3085	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
YE105_C3086	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YE105_C3087	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YE105_C3088	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YE105_C3089	COG0497	DNA recombination
YE105_C3090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YE105_C3092	COG2867	negative regulation of translational initiation
YE105_C3093	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YE105_C3094	COG0582	viral genome integration into host DNA
YE105_C3104	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YE105_C3110	COG3394	polysaccharide catabolic process
YE105_C3111	COG2169	Transcriptional regulator
YE105_C3111	COG1917	Cupin 2, conserved barrel domain protein
YE105_C3112	COG1447	Phosphotransferase system cellobiose-specific component IIA
YE105_C3113	COG2723	6-phospho-beta-galactosidase activity
YE105_C3114	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_C3115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_C3116	COG2133	pyrroloquinoline quinone binding
YE105_C3118	COG0667	Aldo Keto reductase
YE105_C3120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YE105_C3121	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YE105_C3123	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YE105_C3124	COG4413	Urea transporter
YE105_C3125	COG0829	nickel cation binding
YE105_C3126	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YE105_C3127	COG0830	nickel cation binding
YE105_C3128	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
YE105_C3129	COG0804	urea catabolic process
YE105_C3130	COG0832	Belongs to the urease beta subunit family
YE105_C3132	COG1124	(ABC) transporter
YE105_C3134	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YE105_C3140	COG1278	Cold shock
YE105_C3144	COG0477	Major facilitator Superfamily
YE105_C3145	COG2207	Transcriptional regulator
YE105_C3146	COG4575	ribosome binding
YE105_C3148	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YE105_C3150	COG1780	Probably involved in ribonucleotide reductase function
YE105_C3152	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YE105_C3154	COG4176	ABC-type proline glycine betaine transport system permease component
YE105_C3155	COG2113	Glycine betaine
YE105_C3156	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YE105_C3157	COG0328	RNA-DNA hybrid ribonuclease activity
YE105_C3158	COG2226	methyltransferase
YE105_C3159	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YE105_C3160	COG0741	lytic transglycosylase activity
YE105_C3160	COG1388	LysM domain
YE105_C3162	COG3021	interspecies interaction between organisms
YE105_C3163	COG2814	Major facilitator Superfamily
YE105_C3164	COG0583	DNA-binding transcription factor activity
YE105_C3165	COG0656	L-ascorbic acid biosynthetic process
YE105_C3171	COG0191	fructose-bisphosphate aldolase activity
YE105_C3172	COG0126	phosphoglycerate kinase activity
YE105_C3173	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YE105_C3174	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YE105_C3175	COG0501	Belongs to the peptidase M48B family
YE105_C3177	COG1166	arginine decarboxylase activity
YE105_C3178	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YE105_C3181	COG0640	Transcriptional regulator
YE105_C3182	COG3091	SprT-like family
YE105_C3183	COG2356	endonuclease I
YE105_C3184	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YE105_C3185	COG0189	ligase activity
YE105_C3186	COG1678	Uncharacterized ACR, COG1678
YE105_C3187	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YE105_C3188	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YE105_C3190	COG2805	Type II/IV secretion system protein
YE105_C3191	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YE105_C3192	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YE105_C3193	COG0762	integral membrane protein
YE105_C3194	COG1872	DUF167
YE105_C3195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YE105_C3196	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YE105_C3198	COG2066	Belongs to the glutaminase family
YE105_C3199	COG3171	Protein conserved in bacteria
YE105_C3200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YE105_C3201	COG1194	a g-specific adenine glycosylase
YE105_C3202	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YE105_C3203	COG0741	lytic transglycosylase activity
YE105_C3205	COG1982	Orn Lys Arg decarboxylase major
YE105_C3207	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YE105_C3215	COG0531	amino acid
YE105_C3216	COG1982	Orn Lys Arg decarboxylase major
YE105_C3218	COG1289	transmembrane transporter activity
YE105_C3223	COG0024	Methionine aminopeptidase
YE105_C3224	COG4604	ABC transporter, ATP-binding protein
YE105_C3225	COG4605	iron ion homeostasis
YE105_C3227	COG4607	ABC-type enterochelin transport system periplasmic component
YE105_C3231	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_C3233	COG0477	Major facilitator Superfamily
YE105_C3234	COG1609	Transcriptional regulator
YE105_C3236	COG1283	sodium-dependent phosphate transmembrane transporter activity
YE105_C3239	COG0477	Major facilitator Superfamily
YE105_C3242	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_C3243	COG5001	Diguanylate cyclase
YE105_C3245	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
YE105_C3247	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
YE105_C3248	COG0309	Hydrogenase expression formation protein (HypE)
YE105_C3249	COG0409	Hydrogenase expression formation protein
YE105_C3250	COG0298	carbon dioxide binding
YE105_C3251	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YE105_C3252	COG0375	protein maturation
YE105_C3253	COG1773	rubredoxin
YE105_C3254	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YE105_C3255	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
YE105_C3256	COG5557	Pfam Polysulphide reductase, NrfD
YE105_C3257	COG0437	4 iron, 4 sulfur cluster binding
YE105_C3258	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
YE105_C3259	COG3133	Outer membrane lipoprotein
YE105_C3261	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YE105_C3262	COG1191	sigma factor activity
YE105_C3266	COG1516	flagellar protein fliS
YE105_C3267	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YE105_C3269	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YE105_C3271	COG3710	Transcriptional regulator
YE105_C3277	COG1706	bacterial-type flagellum-dependent cell motility
YE105_C3279	COG4786	Flagellar basal body rod
YE105_C3281	COG1749	Flagellar hook protein flgE
YE105_C3282	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YE105_C3283	COG1558	bacterial-type flagellum-dependent cell motility
YE105_C3284	COG1815	bacterial-type flagellum-dependent cell motility
YE105_C3294	COG1677	Flagellar hook-basal body complex protein FliE
YE105_C3295	COG2204	response regulator
YE105_C3299	COG1987	bacterial-type flagellum assembly
YE105_C3301	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YE105_C3304	COG0840	transmembrane signaling receptor activity
YE105_C3305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_C3306	COG2271	Major facilitator Superfamily
YE105_C3307	COG4592	Periplasmic binding protein
YE105_C3308	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_C3309	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_C3310	COG1120	ATPase activity
YE105_C3313	COG2801	Transposase and inactivated derivatives
YE105_C3315	COG1136	(ABC) transporter
YE105_C3315	COG0577	efflux transmembrane transporter activity
YE105_C3326	COG2135	peptidase activity
YE105_C3328	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_C3334	COG4964	Belongs to the GSP D family
YE105_C3344	COG0848	biopolymer transport protein
YE105_C3345	COG0811	peptide transport
YE105_C3346	COG0626	cystathionine gamma-synthase activity
YE105_C3347	COG0586	Pfam SNARE associated Golgi protein
YE105_C3348	COG2207	Transcriptional regulator
YE105_C3349	COG1979	alcohol dehydrogenase
YE105_C3350	COG0656	L-ascorbic acid biosynthetic process
YE105_C3352	COG2132	Multicopper oxidase
YE105_C3353	COG0204	Acyl-transferase
YE105_C3354	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YE105_C3355	COG2249	NAD(P)H dehydrogenase (quinone) activity
YE105_C3356	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YE105_C3358	COG0187	DNA topoisomerase II activity
YE105_C3359	COG3150	esterase
YE105_C3360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YE105_C3361	COG3151	Protein conserved in bacteria
YE105_C3362	COG0494	nUDIX hydrolase
YE105_C3363	COG1538	Outer membrane efflux protein
YE105_C3364	COG5463	Belongs to the UPF0441 family
YE105_C3365	COG0754	glutathionylspermidine amidase activity
YE105_C3366	COG3384	dioxygenase
YE105_C3367	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YE105_C3369	COG0531	amino acid
YE105_C3370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YE105_C3370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YE105_C3371	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YE105_C3372	COG3025	triphosphatase activity
YE105_C3373	COG4991	sh3 domain protein
YE105_C3374	COG0617	tRNA 3'-terminal CCA addition
YE105_C3375	COG1968	undecaprenyl-diphosphatase activity
YE105_C3376	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YE105_C3377	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
YE105_C3378	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YE105_C3380	COG0358	DNA primase activity
YE105_C3381	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YE105_C3383	COG3876	Protein conserved in bacteria
YE105_C3385	COG1472	Belongs to the glycosyl hydrolase 3 family
YE105_C3387	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
YE105_C3388	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C3388	COG1263	PTS System
YE105_C3390	COG0531	amino acid
YE105_C3391	COG0076	glutamate decarboxylase activity
YE105_C3393	COG3247	response to pH
YE105_C3395	COG0446	pyridine nucleotide-disulphide oxidoreductase
YE105_C3395	COG1902	pentaerythritol trinitrate reductase activity
YE105_C3397	COG2813	Specifically methylates the guanine in position
YE105_C3401	COG1451	nucleotide metabolic process
YE105_C3402	COG0673	inositol 2-dehydrogenase activity
YE105_C3403	COG0861	Integral membrane protein TerC family
YE105_C3404	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
YE105_C3406	COG2721	sulfolactate sulfo-lyase activity
YE105_C3407	COG0246	Mannitol dehydrogenase
YE105_C3408	COG1904	glucuronate isomerase
YE105_C3409	COG2271	Major facilitator Superfamily
YE105_C3412	COG0586	Pfam SNARE associated Golgi protein
YE105_C3415	COG4575	ribosome binding
YE105_C3416	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YE105_C3418	COG2259	Doxx family
YE105_C3420	COG0435	Glutathione S-transferase
YE105_C3421	COG0583	DNA-binding transcription factor activity
YE105_C3422	COG1741	Belongs to the pirin family
YE105_C3423	COG1064	alcohol dehydrogenase
YE105_C3424	COG0667	Aldo Keto reductase
YE105_C3428	COG3121	Chaperone
YE105_C3432	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YE105_C3434	COG0792	nuclease activity
YE105_C3435	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YE105_C3436	COG2823	Periplasmic or secreted lipoprotein
YE105_C3437	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YE105_C3438	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YE105_C3439	COG5002	protein histidine kinase activity
YE105_C3439	COG0784	Response regulator, receiver
YE105_C3439	COG2198	Histidine kinase
YE105_C3440	COG1242	4 iron, 4 sulfur cluster binding
YE105_C3441	COG0070	glutamate synthase
YE105_C3441	COG0069	glutamate synthase activity
YE105_C3441	COG0067	glutamate synthase
YE105_C3442	COG0493	'glutamate synthase
YE105_C3445	COG2969	positive regulation of protein catabolic process
YE105_C3446	COG0625	glutathione transferase activity
YE105_C3448	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YE105_C3449	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YE105_C3450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YE105_C3451	COG3105	Protein conserved in bacteria
YE105_C3452	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YE105_C3453	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YE105_C3454	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YE105_C3455	COG5007	Belongs to the BolA IbaG family
YE105_C3456	COG3113	response to antibiotic
YE105_C3457	COG2854	intermembrane phospholipid transfer
YE105_C3458	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YE105_C3459	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YE105_C3460	COG1127	ABC transporter
YE105_C3461	COG0530	calcium, potassium:sodium antiporter activity
YE105_C3462	COG0517	IMP dehydrogenase activity
YE105_C3462	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YE105_C3463	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YE105_C3464	COG3117	lipopolysaccharide transmembrane transporter activity
YE105_C3465	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YE105_C3466	COG1137	ATPase activity
YE105_C3467	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YE105_C3469	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C3470	COG1660	Displays ATPase and GTPase activities
YE105_C3471	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C3473	COG0540	Belongs to the ATCase OTCase family
YE105_C3474	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
YE105_C3476	COG2308	Evidence 4 Homologs of previously reported genes of
YE105_C3480	COG0366	Alpha amylase catalytic
YE105_C3481	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_C3481	COG1263	PTS System
YE105_C3483	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YE105_C3485	COG3093	addiction module antidote protein HigA
YE105_C3486	COG3711	transcriptional antiterminator
YE105_C3486	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C3487	COG2706	6-phosphogluconolactonase activity
YE105_C3490	COG3964	amidohydrolase
YE105_C3496	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YE105_C3497	COG3783	Cytochrome b(562)
YE105_C3499	COG0312	modulator of DNA gyrase
YE105_C3500	COG3028	Belongs to the UPF0307 family
YE105_C3501	COG2732	(Barnase) inhibitor
YE105_C3504	COG1289	transmembrane transporter activity
YE105_C3505	COG1566	PFAM secretion protein HlyD family protein
YE105_C3507	COG0583	DNA-binding transcription factor activity
YE105_C3520	COG0312	modulator of DNA gyrase
YE105_C3521	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YE105_C3522	COG3164	Protein of unknown function
YE105_C3523	COG1530	ribonuclease E activity
YE105_C3525	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YE105_C3526	COG1792	Involved in formation and maintenance of cell shape
YE105_C3527	COG1077	Cell shape determining protein MreB Mrl
YE105_C3528	COG2200	EAL domain
YE105_C3528	COG2199	diguanylate cyclase activity
YE105_C3529	COG0604	alcohol dehydrogenase
YE105_C3531	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
YE105_C3532	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YE105_C3533	COG0511	ligase activity, forming carbon-carbon bonds
YE105_C3534	COG0439	Biotin carboxylase
YE105_C3535	COG3924	membrane
YE105_C3536	COG4145	pantothenate transmembrane transporter activity
YE105_C3537	COG2264	protein methyltransferase activity
YE105_C3538	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YE105_C3539	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YE105_C3540	COG3706	GGDEF domain
YE105_C3540	COG0745	RESPONSE REGULATOR receiver
YE105_C3541	COG3133	Outer membrane lipoprotein
YE105_C3542	COG1278	Cold shock
YE105_C3543	COG1278	Cold shock
YE105_C3545	COG0471	metal ion transport
YE105_C3546	COG1560	Kdo2-lipid A biosynthetic process
YE105_C3548	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_C3549	COG4597	amino acid ABC transporter
YE105_C3550	COG0765	amino acid transport
YE105_C3551	COG1126	abc transporter atp-binding protein
YE105_C3553	COG1380	Effector of murein hydrolase LrgA
YE105_C3554	COG0583	DNA-binding transcription factor activity
YE105_C3555	COG0025	NhaP-type Na H and K H
YE105_C3556	COG2252	PERMEase
YE105_C3559	COG3550	peptidyl-serine autophosphorylation
YE105_C3561	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YE105_C3562	COG2315	Protein conserved in bacteria
YE105_C3564	COG1448	Aminotransferase
YE105_C3565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YE105_C3566	COG0305	Participates in initiation and elongation during chromosome replication
YE105_C3570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YE105_C3572	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YE105_C3573	COG0735	belongs to the Fur family
YE105_C3574	COG3237	CsbD-like
YE105_C3575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YE105_C3576	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YE105_C3577	COG2937	Belongs to the GPAT DAPAT family
YE105_C3578	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YE105_C3579	COG3161	chorismate lyase activity
YE105_C3582	COG4580	involved in the transport of maltose and maltodextrins
YE105_C3584	COG2182	Extracellular solute-binding protein
YE105_C3585	COG1175	transmembrane transport
YE105_C3586	COG3833	ABC-type maltose transport systems, permease component
YE105_C3588	COG0166	Belongs to the GPI family
YE105_C3589	COG0527	aspartate kinase activity
YE105_C3594	COG1414	Transcriptional regulator
YE105_C3595	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
YE105_C3596	COG2224	Isocitrate lyase
YE105_C3597	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YE105_C3598	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
YE105_C3601	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YE105_C3602	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YE105_C3603	COG0009	L-threonylcarbamoyladenylate synthase
YE105_C3604	COG0551	DNA topoisomerase type I activity
YE105_C3606	COG0758	DNA mediated transformation
YE105_C3607	COG0242	peptide deformylase activity
YE105_C3608	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YE105_C3609	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YE105_C3609	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YE105_C3610	COG0569	domain protein
YE105_C3611	COG1970	mechanosensitive ion channel activity
YE105_C3612	COG3036	rescue of stalled ribosome
YE105_C3613	COG0789	Transcriptional regulator
YE105_C3615	COG0203	ribosomal protein L17
YE105_C3616	COG0202	RNA polymerase activity
YE105_C3617	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YE105_C3618	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YE105_C3619	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YE105_C3620	COG0201	protein transport
YE105_C3621	COG0200	Binds to the 23S rRNA
YE105_C3622	COG1841	ribosomal large subunit assembly
YE105_C3623	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YE105_C3624	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YE105_C3625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YE105_C3627	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YE105_C3628	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YE105_C3629	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YE105_C3630	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YE105_C3631	COG0255	Belongs to the universal ribosomal protein uL29 family
YE105_C3632	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YE105_C3633	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YE105_C3634	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YE105_C3635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YE105_C3636	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YE105_C3637	COG0089	rRNA binding
YE105_C3638	COG0088	Forms part of the polypeptide exit tunnel
YE105_C3639	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YE105_C3640	COG0051	transcription antitermination factor activity, RNA binding
YE105_C3643	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YE105_C3645	COG0049	tRNA binding
YE105_C3646	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YE105_C3647	COG2168	tRNA wobble position uridine thiolation
YE105_C3648	COG2923	Belongs to the DsrF TusC family
YE105_C3649	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YE105_C3650	COG2964	Protein conserved in bacteria
YE105_C3651	COG0545	Peptidyl-prolyl cis-trans isomerase
YE105_C3652	COG2900	Belongs to the SlyX family
YE105_C3653	COG1047	Peptidyl-prolyl cis-trans
YE105_C3654	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YE105_C3656	COG2249	NAD(P)H dehydrogenase (quinone) activity
YE105_C3657	COG0488	(ABC) transporter
YE105_C3658	COG1216	Glycosyl transferase, family 2
YE105_C3660	COG2175	clavaminate synthase activity
YE105_C3661	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YE105_C3663	COG4521	taurine ABC transporter
YE105_C3666	COG0429	hydrolase of the alpha beta-hydrolase fold
YE105_C3667	COG3089	Belongs to the UPF0270 family
YE105_C3668	COG3954	Phosphoribulokinase
YE105_C3669	COG1765	OsmC-like protein
YE105_C3671	COG1289	transmembrane transporter activity
YE105_C3674	COG0433	COG0433 Predicted ATPase
YE105_C3675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YE105_C3676	COG1486	melibiose metabolic process
YE105_C3678	COG0738	Major facilitator superfamily
YE105_C3679	COG0402	S-adenosylhomocysteine deaminase activity
YE105_C3680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YE105_C3681	COG2146	nitrite reductase [NAD(P)H] activity
YE105_C3683	COG1648	precorrin-2 dehydrogenase activity
YE105_C3683	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YE105_C3684	COG0180	Tryptophanyl-tRNA synthetase
YE105_C3686	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YE105_C3690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YE105_C3691	COG4796	Type ii and iii secretion system protein
YE105_C3696	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YE105_C3697	COG0494	nUDIX hydrolase
YE105_C3699	COG1011	Hydrolase
YE105_C3700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YE105_C3702	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
YE105_C3706	COG0745	RESPONSE REGULATOR receiver
YE105_C3707	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YE105_C3712	COG2183	response to ionizing radiation
YE105_C3713	COG1918	ferrous iron import across plasma membrane
YE105_C3714	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
YE105_C3717	COG0596	Alpha beta hydrolase
YE105_C3719	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
YE105_C3719	COG0316	Belongs to the HesB IscA family
YE105_C3720	COG1640	4-alpha-glucanotransferase
YE105_C3721	COG0058	SHG alpha-glucan phosphorylase activity
YE105_C3722	COG2909	trisaccharide binding
YE105_C3725	COG0705	Rhomboid family
YE105_C3726	COG1349	DNA-binding transcription factor activity
YE105_C3727	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YE105_C3728	COG0058	SHG alpha-glucan phosphorylase activity
YE105_C3729	COG0297	glycogen (starch) synthase activity
YE105_C3731	COG1523	belongs to the glycosyl hydrolase 13 family
YE105_C3732	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YE105_C3733	COG3275	phosphorelay sensor kinase activity
YE105_C3737	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YE105_C3738	COG2095	MarC family integral membrane protein
YE105_C3739	COG3265	gluconokinase activity
YE105_C3740	COG2610	gluconate transmembrane transporter activity
YE105_C3741	COG1609	Transcriptional regulator
YE105_C3742	COG1741	Belongs to the pirin family
YE105_C3743	COG1247	-acetyltransferase
YE105_C3744	COG1082	Xylose isomerase domain protein TIM barrel
YE105_C3745	COG0673	inositol 2-dehydrogenase activity
YE105_C3747	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_C3749	COG3718	enzyme involved in inositol metabolism
YE105_C3751	COG2814	Major facilitator Superfamily
YE105_C3752	COG0583	DNA-binding transcription factor activity
YE105_C3754	COG0561	phosphatase activity
YE105_C3756	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_C3756	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_C3757	COG0583	DNA-binding transcription factor activity
YE105_C3758	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YE105_C3758	COG1648	precorrin-2 dehydrogenase activity
YE105_C3760	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YE105_C3762	COG4865	methylaspartate mutase activity
YE105_C3763	COG3799	methylaspartate ammonia-lyase activity
YE105_C3766	COG1301	dicarboxylic acid transport
YE105_C3767	COG2081	HI0933 family
YE105_C3768	COG0306	phosphate transporter
YE105_C3770	COG0589	response to stress
YE105_C3773	COG0742	ribosomal rna small subunit methyltransferase
YE105_C3775	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YE105_C3776	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_C3778	COG1295	ribonuclease BN
YE105_C3779	COG2134	cdp-diacylglycerol pyrophosphatase
YE105_C3780	COG2982	Protein involved in outer membrane biogenesis
YE105_C3781	COG2200	EAL domain
YE105_C3782	COG1942	4-Oxalocrotonate Tautomerase
YE105_C3783	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_C3784	COG0612	Peptidase, M16
YE105_C3785	COG1301	dicarboxylic acid transport
YE105_C3788	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YE105_C3789	COG2200	EAL domain
YE105_C3789	COG2199	diguanylate cyclase activity
YE105_C3790	COG0457	Tetratricopeptide repeat
YE105_C3790	COG3118	belongs to the thioredoxin family
YE105_C3791	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YE105_C3792	COG1215	transferase activity, transferring glycosyl groups
YE105_C3793	COG1215	transferase activity, transferring glycosyl groups
YE105_C3794	COG1192	Involved in chromosome partitioning
YE105_C3798	COG2194	sulfuric ester hydrolase activity
YE105_C3799	COG4608	Belongs to the ABC transporter superfamily
YE105_C3800	COG0444	Belongs to the ABC transporter superfamily
YE105_C3801	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YE105_C3802	COG0601	transmembrane transport
YE105_C3803	COG0747	negative chemotaxis
YE105_C3806	COG1764	response to oxidative stress
YE105_C3807	COG2194	sulfuric ester hydrolase activity
YE105_C3808	COG2197	response regulator
YE105_C3809	COG3851	Histidine kinase
YE105_C3810	COG2271	Major facilitator Superfamily
YE105_C3813	COG2831	hemolysin activation secretion protein
YE105_C3814	COG3210	domain, Protein
YE105_C3816	COG3328	transposase activity
YE105_C3823	COG1609	Transcriptional regulator
YE105_C3824	COG1940	carbohydrate kinase activity
YE105_C3825	COG1447	Phosphotransferase system cellobiose-specific component IIA
YE105_C3826	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_C3827	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_C3828	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_C3830	COG2723	6-phospho-beta-galactosidase activity
YE105_C3831	COG1482	cell wall glycoprotein biosynthetic process
YE105_C3836	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
YE105_C3837	COG2986	histidine ammonia-lyase
YE105_C3845	COG0582	viral genome integration into host DNA
YE105_C3846	COG1609	Transcriptional regulator
YE105_C3846	COG2207	Transcriptional regulator
YE105_C3847	COG4214	carbohydrate transport
YE105_C3849	COG4213	ABC transporter substrate-binding protein
YE105_C3850	COG2115	Belongs to the xylose isomerase family
YE105_C3851	COG1070	Carbohydrate kinase
YE105_C3852	COG3121	Chaperone
YE105_C3855	COG3274	enterobacterial common antigen metabolic process
YE105_C3857	COG3276	selenocysteine insertion sequence binding
YE105_C3858	COG1921	L-seryl-tRNASec selenium transferase activity
YE105_C3859	COG3058	Necessary for formate dehydrogenase activity
YE105_C3860	COG2864	formate dehydrogenase
YE105_C3861	COG0437	4 iron, 4 sulfur cluster binding
YE105_C3862	COG3383	formate dehydrogenase (NAD+) activity
YE105_C3862	COG0243	molybdopterin cofactor binding
YE105_C3863	COG0243	molybdopterin cofactor binding
YE105_C3863	COG3383	formate dehydrogenase (NAD+) activity
YE105_C3864	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YE105_C3865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YE105_C3867	COG0840	transmembrane signaling receptor activity
YE105_C3868	COG2258	MOSC domain
YE105_C3872	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_C3874	COG3722	fumarate hydratase activity
YE105_C3875	COG0246	Mannitol dehydrogenase
YE105_C3876	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_C3876	COG2213	PTS system mannitol-specific
YE105_C3878	COG0751	glycine-tRNA ligase activity
YE105_C3879	COG0752	glycyl-tRNA synthetase alpha subunit
YE105_C3880	COG2818	Glycosylase
YE105_C3881	COG0456	acetyltransferase
YE105_C3887	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YE105_C3888	COG0366	Alpha amylase catalytic
YE105_C3889	COG3977	Valine--pyruvate aminotransferase
YE105_C3890	COG2985	domain, Protein
YE105_C3890	COG0569	domain protein
YE105_C3893	COG5645	(Lipo)protein
YE105_C3894	COG0823	Involved in the tonB-independent uptake of proteins
YE105_C3896	COG2423	ornithine cyclodeaminase activity
YE105_C3897	COG0561	phosphatase activity
YE105_C3898	COG0187	DNA topoisomerase II activity
YE105_C3899	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YE105_C3900	COG0592	DNA-directed DNA polymerase activity
YE105_C3901	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YE105_C3902	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YE105_C3903	COG0594	ribonuclease P activity
YE105_C3905	COG0706	membrane insertase activity
YE105_C3906	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YE105_C3907	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YE105_C3910	COG2011	ABC-type metal ion transport system permease component
YE105_C3911	COG0840	transmembrane signaling receptor activity
YE105_C3912	COG0431	NADPH-dependent FMN reductase
YE105_C3914	COG4566	intracellular signal transduction
YE105_C3916	COG2252	PERMEase
YE105_C3917	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_C3918	COG0765	amino acid transport
YE105_C3919	COG0765	amino acid transport
YE105_C3920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_C3922	COG0704	Plays a role in the regulation of phosphate uptake
YE105_C3924	COG0581	inorganic phosphate transmembrane transporter activity
YE105_C3925	COG0573	inorganic phosphate transmembrane transporter activity
YE105_C3926	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YE105_C3927	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YE105_C3928	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YE105_C3929	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YE105_C3930	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YE105_C3931	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YE105_C3932	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YE105_C3933	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YE105_C3934	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YE105_C3936	COG0356	it plays a direct role in the translocation of protons across the membrane
YE105_C3937	COG3312	ion transport
YE105_C3938	COG0357	Ribosomal RNA small subunit methyltransferase G
YE105_C3939	COG0445	tRNA wobble uridine modification
YE105_P0007	COG4886	Leucine-rich repeat (LRR) protein
YE105_P0007	COG4886	Leucine-rich repeat (LRR) protein
YE105_P0009	COG3328	transposase activity
YE105_P0025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YE105_P0026	COG4790	Type iii secretion
YE105_P0027	COG4794	Type iii secretion
YE105_P0028	COG4791	protein targeting
YE105_P0029	COG4792	protein secretion
YE105_P0054	COG3609	addiction module antidote protein, CC2985 family
YE105_P0055	COG1475	DNA binding
YE105_P0056	COG1192	Involved in chromosome partitioning
YE105_P0061	COG2963	transposase activity
YE105_P0071	COG0640	Transcriptional regulator
YE105_P0072	COG0431	NADPH-dependent FMN reductase