locus-tag	class	description
YEY1_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YEY1_00010	COG0592	DNA-directed DNA polymerase activity
YEY1_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YEY1_00020	COG0187	DNA topoisomerase II activity
YEY1_00025	COG0561	phosphatase activity
YEY1_00030	COG2423	ornithine cyclodeaminase activity
YEY1_00040	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_00045	COG5645	(Lipo)protein
YEY1_00065	COG0569	domain protein
YEY1_00065	COG2985	domain, Protein
YEY1_00070	COG3977	Valine--pyruvate aminotransferase
YEY1_00075	COG0366	Alpha amylase catalytic
YEY1_00080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YEY1_00110	COG0456	acetyltransferase
YEY1_00115	COG2818	Glycosylase
YEY1_00120	COG0752	glycyl-tRNA synthetase alpha subunit
YEY1_00125	COG0751	glycine-tRNA ligase activity
YEY1_00140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_00140	COG2213	PTS system mannitol-specific
YEY1_00145	COG0246	Mannitol dehydrogenase
YEY1_00150	COG3722	fumarate hydratase activity
YEY1_00160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_00180	COG2258	MOSC domain
YEY1_00185	COG0840	transmembrane signaling receptor activity
YEY1_00195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YEY1_00200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YEY1_00205	COG3383	formate dehydrogenase (NAD+) activity
YEY1_00205	COG0243	molybdopterin cofactor binding
YEY1_00210	COG3383	formate dehydrogenase (NAD+) activity
YEY1_00210	COG0243	molybdopterin cofactor binding
YEY1_00215	COG0437	4 iron, 4 sulfur cluster binding
YEY1_00220	COG2864	formate dehydrogenase
YEY1_00225	COG3058	Necessary for formate dehydrogenase activity
YEY1_00230	COG1921	L-seryl-tRNASec selenium transferase activity
YEY1_00235	COG3276	selenocysteine insertion sequence binding
YEY1_00245	COG3274	enterobacterial common antigen metabolic process
YEY1_00260	COG3121	Chaperone
YEY1_00265	COG1070	Carbohydrate kinase
YEY1_00270	COG2115	Belongs to the xylose isomerase family
YEY1_00275	COG4213	ABC transporter substrate-binding protein
YEY1_00285	COG4214	carbohydrate transport
YEY1_00295	COG0582	viral genome integration into host DNA
YEY1_00345	COG2986	histidine ammonia-lyase
YEY1_00350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
YEY1_00375	COG1482	cell wall glycoprotein biosynthetic process
YEY1_00380	COG2723	6-phospho-beta-galactosidase activity
YEY1_00395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_00400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_00405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_00410	COG1447	Phosphotransferase system cellobiose-specific component IIA
YEY1_00415	COG1940	carbohydrate kinase activity
YEY1_00420	COG1609	Transcriptional regulator
YEY1_00445	COG3328	transposase activity
YEY1_00455	COG3210	domain, Protein
YEY1_00460	COG2831	hemolysin activation secretion protein
YEY1_00480	COG2271	Major facilitator Superfamily
YEY1_00485	COG3851	Histidine kinase
YEY1_00490	COG2197	response regulator
YEY1_00495	COG2194	sulfuric ester hydrolase activity
YEY1_00500	COG1764	response to oxidative stress
YEY1_00515	COG0747	negative chemotaxis
YEY1_00520	COG0601	transmembrane transport
YEY1_00525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YEY1_00530	COG0444	Belongs to the ABC transporter superfamily
YEY1_00535	COG4608	Belongs to the ABC transporter superfamily
YEY1_00540	COG2194	sulfuric ester hydrolase activity
YEY1_00560	COG1192	Involved in chromosome partitioning
YEY1_00565	COG1215	transferase activity, transferring glycosyl groups
YEY1_00570	COG1215	transferase activity, transferring glycosyl groups
YEY1_00575	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YEY1_00590	COG2199	diguanylate cyclase activity
YEY1_00590	COG2200	EAL domain
YEY1_00595	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YEY1_00610	COG1301	dicarboxylic acid transport
YEY1_00615	COG0612	Peptidase, M16
YEY1_00625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_00630	COG1942	4-Oxalocrotonate Tautomerase
YEY1_00635	COG2200	EAL domain
YEY1_00640	COG2982	Protein involved in outer membrane biogenesis
YEY1_00645	COG2134	cdp-diacylglycerol pyrophosphatase
YEY1_00650	COG1295	ribonuclease BN
YEY1_00670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_00680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YEY1_00690	COG0742	ribosomal rna small subunit methyltransferase
YEY1_00705	COG0589	response to stress
YEY1_00715	COG0306	phosphate transporter
YEY1_00720	COG2081	HI0933 family
YEY1_00740	COG3799	methylaspartate ammonia-lyase activity
YEY1_00745	COG4865	methylaspartate mutase activity
YEY1_00755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YEY1_00765	COG1648	precorrin-2 dehydrogenase activity
YEY1_00765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YEY1_00770	COG0583	DNA-binding transcription factor activity
YEY1_00775	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_00775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_00785	COG0561	phosphatase activity
YEY1_00795	COG0583	DNA-binding transcription factor activity
YEY1_00800	COG2814	Major facilitator Superfamily
YEY1_00810	COG3718	enzyme involved in inositol metabolism
YEY1_00820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_00830	COG0673	inositol 2-dehydrogenase activity
YEY1_00835	COG1082	Xylose isomerase domain protein TIM barrel
YEY1_00840	COG1247	-acetyltransferase
YEY1_00845	COG1741	Belongs to the pirin family
YEY1_00850	COG1609	Transcriptional regulator
YEY1_00855	COG2610	gluconate transmembrane transporter activity
YEY1_00860	COG3265	gluconokinase activity
YEY1_00865	COG2095	MarC family integral membrane protein
YEY1_00870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YEY1_00890	COG3275	phosphorelay sensor kinase activity
YEY1_00895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YEY1_00900	COG1523	belongs to the glycosyl hydrolase 13 family
YEY1_00915	COG0297	glycogen (starch) synthase activity
YEY1_00920	COG0058	SHG alpha-glucan phosphorylase activity
YEY1_00925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YEY1_00940	COG1349	DNA-binding transcription factor activity
YEY1_00945	COG0705	Rhomboid family
YEY1_00960	COG2909	trisaccharide binding
YEY1_00965	COG0058	SHG alpha-glucan phosphorylase activity
YEY1_00970	COG1640	4-alpha-glucanotransferase
YEY1_00980	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
YEY1_00980	COG0316	Belongs to the HesB IscA family
YEY1_00995	COG0596	Alpha beta hydrolase
YEY1_01010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
YEY1_01015	COG1918	ferrous iron import across plasma membrane
YEY1_01020	COG2183	response to ionizing radiation
YEY1_01045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YEY1_01050	COG0745	RESPONSE REGULATOR receiver
YEY1_01065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
YEY1_01075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YEY1_01080	COG1011	Hydrolase
YEY1_01090	COG0494	nUDIX hydrolase
YEY1_01095	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YEY1_01120	COG4796	Type ii and iii secretion system protein
YEY1_01125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YEY1_01145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YEY1_01155	COG0180	Tryptophanyl-tRNA synthetase
YEY1_01160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YEY1_01160	COG1648	precorrin-2 dehydrogenase activity
YEY1_01170	COG2146	nitrite reductase [NAD(P)H] activity
YEY1_01175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YEY1_01180	COG0402	S-adenosylhomocysteine deaminase activity
YEY1_01185	COG0738	Major facilitator superfamily
YEY1_01195	COG1486	melibiose metabolic process
YEY1_01200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YEY1_01205	COG0433	COG0433 Predicted ATPase
YEY1_01220	COG1289	transmembrane transporter activity
YEY1_01235	COG1765	OsmC-like protein
YEY1_01240	COG3954	Phosphoribulokinase
YEY1_01245	COG3089	Belongs to the UPF0270 family
YEY1_01250	COG0429	hydrolase of the alpha beta-hydrolase fold
YEY1_01265	COG4521	taurine ABC transporter
YEY1_01275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YEY1_01280	COG2175	clavaminate synthase activity
YEY1_01290	COG1216	Glycosyl transferase, family 2
YEY1_01295	COG0488	(ABC) transporter
YEY1_01300	COG2249	NAD(P)H dehydrogenase (quinone) activity
YEY1_01310	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YEY1_01315	COG1047	Peptidyl-prolyl cis-trans
YEY1_01320	COG2900	Belongs to the SlyX family
YEY1_01325	COG0545	Peptidyl-prolyl cis-trans isomerase
YEY1_01330	COG2964	Protein conserved in bacteria
YEY1_01335	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YEY1_01340	COG2923	Belongs to the DsrF TusC family
YEY1_01345	COG2168	tRNA wobble position uridine thiolation
YEY1_01350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YEY1_01355	COG0049	tRNA binding
YEY1_01370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YEY1_01385	COG0051	transcription antitermination factor activity, RNA binding
YEY1_01390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YEY1_01395	COG0088	Forms part of the polypeptide exit tunnel
YEY1_01400	COG0089	rRNA binding
YEY1_01405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YEY1_01410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YEY1_01415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YEY1_01420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YEY1_01425	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YEY1_01430	COG0255	Belongs to the universal ribosomal protein uL29 family
YEY1_01435	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YEY1_01440	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YEY1_01445	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YEY1_01450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YEY1_01455	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YEY1_01465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YEY1_01470	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YEY1_01475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YEY1_01480	COG1841	ribosomal large subunit assembly
YEY1_01485	COG0200	Binds to the 23S rRNA
YEY1_01490	COG0201	protein transport
YEY1_01495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YEY1_01500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YEY1_01505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YEY1_01510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YEY1_01515	COG0202	RNA polymerase activity
YEY1_01520	COG0203	ribosomal protein L17
YEY1_01530	COG0789	Transcriptional regulator
YEY1_01535	COG3036	rescue of stalled ribosome
YEY1_01545	COG1970	mechanosensitive ion channel activity
YEY1_01550	COG0569	domain protein
YEY1_01555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YEY1_01555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YEY1_01565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YEY1_01570	COG0242	peptide deformylase activity
YEY1_01575	COG0758	DNA mediated transformation
YEY1_01585	COG0551	DNA topoisomerase type I activity
YEY1_01590	COG0009	L-threonylcarbamoyladenylate synthase
YEY1_01595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YEY1_01600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YEY1_01645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YEY1_01650	COG3162	membrane
YEY1_01655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YEY1_01660	COG1301	dicarboxylic acid transport
YEY1_01665	COG2197	response regulator
YEY1_01820	COG2391	methyltransferase activity
YEY1_01830	COG0425	Belongs to the sulfur carrier protein TusA family
YEY1_01845	COG3712	iron ion homeostasis
YEY1_01850	COG4771	TonB-dependent receptor
YEY1_01855	COG4178	(ABC) transporter
YEY1_01860	COG0612	Peptidase, M16
YEY1_01865	COG2161	toxin-antitoxin pair type II binding
YEY1_01870	COG4115	mRNA cleavage
YEY1_01875	COG3264	Mechanosensitive ion channel
YEY1_01875	COG1511	domain protein
YEY1_01880	COG4774	siderophore transport
YEY1_01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_01895	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YEY1_01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YEY1_01905	COG4558	Periplasmic binding protein
YEY1_01910	COG3720	iron ion transport
YEY1_01930	COG3721	Heme iron utilization protein
YEY1_01940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YEY1_01945	COG0814	amino acid
YEY1_01950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YEY1_01955	COG1882	Formate acetyltransferase
YEY1_01965	COG1309	transcriptional regulator
YEY1_01970	COG1929	Belongs to the glycerate kinase type-1 family
YEY1_01975	COG4232	protein-disulfide reductase activity
YEY1_01985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YEY1_02000	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YEY1_02005	COG0459	protein refolding
YEY1_02025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YEY1_02035	COG2076	Multidrug Resistance protein
YEY1_02045	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YEY1_02050	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YEY1_02055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YEY1_02060	COG1053	succinate dehydrogenase
YEY1_02065	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
YEY1_02070	COG3264	Mechanosensitive ion channel
YEY1_02070	COG1511	domain protein
YEY1_02075	COG0688	phosphatidylethanolamine metabolic process
YEY1_02080	COG1162	GTPase activity
YEY1_02085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YEY1_02105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YEY1_02110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YEY1_02110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YEY1_02115	COG0802	atpase or kinase
YEY1_02120	COG0860	N-Acetylmuramoyl-L-alanine amidase
YEY1_02125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YEY1_02130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YEY1_02135	COG1923	regulation of RNA biosynthetic process
YEY1_02140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YEY1_02145	COG0330	HflC and HflK could
YEY1_02150	COG0330	HflC and HflK could
YEY1_02155	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YEY1_02160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YEY1_02165	COG1959	2 iron, 2 sulfur cluster binding
YEY1_02170	COG0557	exoribonuclease II activity
YEY1_02180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YEY1_02190	COG1960	acyl-CoA dehydrogenase activity
YEY1_02200	COG3650	response to hydrogen peroxide
YEY1_02205	COG1073	alpha beta
YEY1_02220	COG0360	Binds together with S18 to 16S ribosomal RNA
YEY1_02225	COG2965	DNA replication, synthesis of RNA primer
YEY1_02230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YEY1_02235	COG0359	binds to the 23S rRNA
YEY1_02245	COG3061	Opacity-associated protein A
YEY1_02250	COG0545	Peptidyl-prolyl cis-trans isomerase
YEY1_02260	COG0737	Belongs to the 5'-nucleotidase family
YEY1_02265	COG1218	3'(2'),5'-bisphosphate nucleotidase
YEY1_02270	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YEY1_02280	COG1253	flavin adenine dinucleotide binding
YEY1_02285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YEY1_02295	COG2911	Protein conserved in bacteria
YEY1_02300	COG2105	PFAM AIG2 family protein
YEY1_02305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YEY1_02315	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YEY1_02320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YEY1_02330	COG1438	arginine binding
YEY1_02335	COG0039	L-malate dehydrogenase activity
YEY1_02340	COG3423	Transcriptional regulator
YEY1_02350	COG0142	geranyltranstransferase activity
YEY1_02355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YEY1_02360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YEY1_02365	COG0697	spore germination
YEY1_02370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YEY1_02375	COG0642	Histidine kinase
YEY1_02380	COG0745	RESPONSE REGULATOR receiver
YEY1_02385	COG2027	D-alanyl-D-alanine carboxypeptidase
YEY1_02390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YEY1_02395	COG1534	Rna-binding protein
YEY1_02400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YEY1_02405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YEY1_02410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YEY1_02415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YEY1_02420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YEY1_02435	COG0779	Required for maturation of 30S ribosomal subunits
YEY1_02440	COG0195	Participates in both transcription termination and antitermination
YEY1_02445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YEY1_02450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YEY1_02455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YEY1_02460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YEY1_02465	COG1185	polyribonucleotide nucleotidyltransferase activity
YEY1_02480	COG0513	Belongs to the DEAD box helicase family
YEY1_02490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YEY1_02505	COG0814	amino acid
YEY1_02510	COG3681	Belongs to the UPF0597 family
YEY1_02530	COG3153	acetyltransferase
YEY1_02535	COG2827	Endonuclease containing a URI domain
YEY1_02540	COG0531	amino acid
YEY1_02545	COG1982	Orn Lys Arg decarboxylase major
YEY1_02565	COG1653	transport
YEY1_02575	COG0395	ABC-type sugar transport system, permease component
YEY1_02580	COG3842	ATPase activity
YEY1_02590	COG3787	Belongs to the UPF0306 family
YEY1_02605	COG0702	epimerase
YEY1_02610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YEY1_02620	COG3454	Phosphonate metabolism
YEY1_02625	COG4778	phosphonate C-P lyase system protein PhnL
YEY1_02630	COG4107	phosphonate C-P lyase system protein PhnK
YEY1_02635	COG3627	carbon phosphorus lyase activity
YEY1_02645	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YEY1_02650	COG3624	Phosphonate C-P lyase system protein PhnG
YEY1_02655	COG2188	Transcriptional regulator
YEY1_02695	COG4608	Belongs to the ABC transporter superfamily
YEY1_02700	COG0444	Belongs to the ABC transporter superfamily
YEY1_02710	COG0601	transmembrane transport
YEY1_02725	COG2731	YhcH YjgK YiaL family protein
YEY1_02740	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YEY1_02760	COG2927	DNA polymerase III (CHI subunit)
YEY1_02765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YEY1_02770	COG0795	lipopolysaccharide-transporting ATPase activity
YEY1_02775	COG0795	lipopolysaccharide-transporting ATPase activity
YEY1_02825	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
YEY1_02825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YEY1_02830	COG0454	-acetyltransferase
YEY1_02880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YEY1_02885	COG1830	Aldolase
YEY1_02890	COG1879	ABC-type sugar transport system periplasmic component
YEY1_02895	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_02900	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_02905	COG1129	ABC transporter
YEY1_02915	COG2390	Transcriptional regulator
YEY1_02920	COG1070	Carbohydrate kinase
YEY1_02925	COG0859	PFAM glycosyl transferase family 9
YEY1_02940	COG2235	arginine
YEY1_02950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_02955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_02965	COG2376	Dihydroxyacetone kinase
YEY1_02970	COG1461	Dihydroxyacetone kinase
YEY1_02975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_02975	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
YEY1_02975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YEY1_02985	COG2192	nodulation
YEY1_03015	COG3284	Transcriptional regulator
YEY1_03050	COG4772	TonB-dependent receptor
YEY1_03060	COG3706	GGDEF domain
YEY1_03075	COG0583	DNA-binding transcription factor activity
YEY1_03080	COG0667	Aldo Keto reductase
YEY1_03085	COG2813	Specifically methylates the guanine in position
YEY1_03090	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YEY1_03095	COG0456	acetyltransferase
YEY1_03100	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
YEY1_03105	COG2823	Periplasmic or secreted lipoprotein
YEY1_03115	COG4667	esterase of the alpha-beta hydrolase superfamily
YEY1_03120	COG0084	hydrolase, TatD family'
YEY1_03125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YEY1_03130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YEY1_03135	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
YEY1_03140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YEY1_03145	COG0813	purine-nucleoside phosphorylase activity
YEY1_03150	COG3726	membrane protein affecting hemolysin expression
YEY1_03155	COG0560	Phosphoserine phosphatase
YEY1_03180	COG0604	alcohol dehydrogenase
YEY1_03195	COG0488	(ABC) transporter
YEY1_03200	COG2885	chlorophyll binding
YEY1_03205	COG2199	diguanylate cyclase activity
YEY1_03215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YEY1_03220	COG0741	lytic transglycosylase activity
YEY1_03225	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YEY1_03230	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
YEY1_03235	COG0406	alpha-ribazole phosphatase activity
YEY1_03240	COG2207	Transcriptional regulator
YEY1_03240	COG3708	Transcriptional regulator
YEY1_03245	COG3045	CreA protein
YEY1_03250	COG0745	RESPONSE REGULATOR receiver
YEY1_03265	COG0083	homoserine kinase activity
YEY1_03285	COG3022	response to hydroperoxide
YEY1_03290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YEY1_03295	COG0521	Mo-molybdopterin cofactor biosynthetic process
YEY1_03310	COG1584	GPR1 FUN34 yaaH family protein
YEY1_03315	COG0443	Heat shock 70 kDa protein
YEY1_03320	COG0484	heat shock protein binding
YEY1_03330	COG0583	DNA-binding transcription factor activity
YEY1_03335	COG0268	Binds directly to 16S ribosomal RNA
YEY1_03350	COG0196	riboflavin kinase activity
YEY1_03355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YEY1_03360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YEY1_03365	COG1047	Peptidyl-prolyl cis-trans
YEY1_03370	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YEY1_03375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YEY1_03380	COG0505	Belongs to the CarA family
YEY1_03385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YEY1_03390	COG1280	lysine exporter protein (LysE YggA)
YEY1_03395	COG2966	Psort location CytoplasmicMembrane, score
YEY1_03400	COG3610	response to peptide
YEY1_03405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YEY1_03410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YEY1_03415	COG2967	ApaG domain
YEY1_03420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YEY1_03430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YEY1_03435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YEY1_03440	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YEY1_03445	COG0564	pseudouridine synthase activity
YEY1_03450	COG1388	LysM domain
YEY1_03450	COG1470	cell adhesion involved in biofilm formation
YEY1_03455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YEY1_03460	COG0417	DNA replication proofreading
YEY1_03465	COG0586	Pfam SNARE associated Golgi protein
YEY1_03475	COG1178	ABC-type Fe3 transport system permease component
YEY1_03480	COG4143	(ABC) transporter
YEY1_03495	COG4533	DNA binding
YEY1_03500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YEY1_03510	COG2814	Major facilitator Superfamily
YEY1_03515	COG0814	amino acid
YEY1_03535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YEY1_03540	COG0473	3-isopropylmalate dehydrogenase activity
YEY1_03545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YEY1_03560	COG1022	Amp-dependent synthetase and ligase
YEY1_03565	COG0028	Belongs to the TPP enzyme family
YEY1_03575	COG1609	Transcriptional regulator
YEY1_03585	COG2001	Belongs to the MraZ family
YEY1_03590	COG0275	rRNA processing
YEY1_03595	COG3116	cell division
YEY1_03600	COG0768	penicillin binding
YEY1_03605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YEY1_03610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YEY1_03615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YEY1_03625	COG0772	Belongs to the SEDS family
YEY1_03630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YEY1_03635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YEY1_03645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YEY1_03650	COG0849	cell division
YEY1_03655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YEY1_03675	COG0653	protein targeting
YEY1_03680	COG0494	nUDIX hydrolase
YEY1_03685	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YEY1_03695	COG0237	dephospho-CoA kinase activity
YEY1_03705	COG0516	GMP reductase activity
YEY1_03710	COG1459	type II secretion system
YEY1_03715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YEY1_03720	COG4969	Belongs to the N-Me-Phe pilin family
YEY1_03735	COG3725	Membrane protein required for beta-lactamase induction
YEY1_03740	COG1113	amino acid transport
YEY1_03745	COG2186	Transcriptional regulator
YEY1_03750	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YEY1_03755	COG0508	dehydrogenase complex catalyzes the overall conversion of
YEY1_03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_03770	COG4977	sequence-specific DNA binding
YEY1_03785	COG3112	Uncharacterised protein family (UPF0231)
YEY1_03790	COG0697	spore germination
YEY1_03800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
YEY1_03805	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YEY1_03815	COG2132	Multicopper oxidase
YEY1_03825	COG0288	reversible hydration of carbon dioxide
YEY1_03830	COG1131	(ABC) transporter
YEY1_03835	COG0842	Transport permease protein
YEY1_03840	COG0726	polysaccharide deacetylase
YEY1_03845	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
YEY1_03850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YEY1_03855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YEY1_03860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YEY1_03875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YEY1_03885	COG1489	DNA binding
YEY1_03890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YEY1_03895	COG1643	Atp-dependent helicase
YEY1_03905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YEY1_03910	COG1120	ATPase activity
YEY1_03915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YEY1_03920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YEY1_03925	COG2223	nitrite transmembrane transporter activity
YEY1_03930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YEY1_03940	COG0316	Belongs to the HesB IscA family
YEY1_03945	COG2860	membrane
YEY1_03955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YEY1_03960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YEY1_03965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YEY1_03970	COG3850	Histidine kinase
YEY1_03970	COG2205	protein histidine kinase activity
YEY1_03970	COG4999	Histidine kinase
YEY1_03970	COG3437	response regulator, receiver
YEY1_03975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YEY1_03980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YEY1_03985	COG3956	TIGRFAM MazG family protein
YEY1_03990	COG0504	CTP synthase activity
YEY1_03995	COG0148	phosphopyruvate hydratase activity
YEY1_04000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YEY1_04010	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
YEY1_04020	COG3079	Belongs to the UPF0149 family
YEY1_04025	COG0006	proline dipeptidase activity
YEY1_04030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YEY1_04035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YEY1_04040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YEY1_04045	COG0509	glycine decarboxylation via glycine cleavage system
YEY1_04050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YEY1_04050	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YEY1_04060	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_04070	COG1272	protein, Hemolysin III
YEY1_04080	COG0354	folic acid binding
YEY1_04085	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YEY1_04095	COG0745	RESPONSE REGULATOR receiver
YEY1_04105	COG4452	Inner membrane protein CreD
YEY1_04110	COG0716	FMN binding
YEY1_04115	COG4974	Belongs to the 'phage' integrase family
YEY1_04120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YEY1_04125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YEY1_04140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YEY1_04170	COG2944	sequence-specific DNA binding
YEY1_04175	COG3328	transposase activity
YEY1_04190	COG4319	ketosteroid isomerase
YEY1_04195	COG3706	GGDEF domain
YEY1_04210	COG0484	heat shock protein binding
YEY1_04220	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_04225	COG1733	regulation of RNA biosynthetic process
YEY1_04230	COG0288	reversible hydration of carbon dioxide
YEY1_04265	COG2165	general secretion pathway protein
YEY1_04305	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
YEY1_04345	COG2814	Major facilitator Superfamily
YEY1_04350	COG0583	DNA-binding transcription factor activity
YEY1_04355	COG0019	diaminopimelate decarboxylase activity
YEY1_04360	COG1609	Transcriptional regulator
YEY1_04380	COG0204	Acyl-transferase
YEY1_04380	COG0318	PFAM AMP-dependent synthetase and ligase
YEY1_04385	COG0477	Major facilitator Superfamily
YEY1_04390	COG0667	Aldo Keto reductase
YEY1_04395	COG0861	Integral membrane protein TerC family
YEY1_04400	COG3066	DNA modification
YEY1_04405	COG1051	belongs to the nudix hydrolase family
YEY1_04415	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YEY1_04420	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YEY1_04440	COG4967	type IV pilus modification protein PilV
YEY1_04445	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YEY1_04450	COG1025	Belongs to the peptidase M16 family
YEY1_04455	COG1074	ATP-dependent DNA helicase activity
YEY1_04460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YEY1_04470	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
YEY1_04475	COG2363	Small membrane protein
YEY1_04480	COG0583	DNA-binding transcription factor activity
YEY1_04495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YEY1_04500	COG2166	iron-sulfur cluster assembly
YEY1_04505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YEY1_04510	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YEY1_04530	COG0860	N-Acetylmuramoyl-L-alanine amidase
YEY1_04535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YEY1_04535	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YEY1_04550	COG3328	transposase activity
YEY1_04555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YEY1_04560	COG1611	Belongs to the LOG family
YEY1_04565	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YEY1_04565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YEY1_04575	COG3098	single-species biofilm formation
YEY1_04580	COG0564	pseudouridine synthase activity
YEY1_04595	COG2171	N-acyltransferase activity
YEY1_04600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YEY1_04605	COG0024	Methionine aminopeptidase
YEY1_04615	COG0052	Belongs to the universal ribosomal protein uS2 family
YEY1_04620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YEY1_04625	COG0528	UMP kinase activity
YEY1_04630	COG0233	cytoplasmic translational termination
YEY1_04635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YEY1_04640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YEY1_04645	COG0575	Belongs to the CDS family
YEY1_04650	COG0750	zinc metalloprotease
YEY1_04660	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YEY1_04665	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YEY1_04670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YEY1_04675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YEY1_04680	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YEY1_04685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YEY1_04695	COG0825	malonyl-CoA metabolic process
YEY1_04705	COG0346	lactoylglutathione lyase activity
YEY1_04710	COG0037	tRNA processing
YEY1_04720	COG4568	rho-dependent transcription termination
YEY1_04730	COG4681	YaeQ
YEY1_04740	COG3015	lipoprotein NlpE involved in copper resistance
YEY1_04745	COG0442	prolyl-tRNA aminoacylation
YEY1_04750	COG1720	tRNA m6t6A37 methyltransferase activity
YEY1_04760	COG1464	Belongs to the NlpA lipoprotein family
YEY1_04765	COG2011	ABC-type metal ion transport system permease component
YEY1_04775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YEY1_04810	COG3328	transposase activity
YEY1_04820	COG0656	L-ascorbic acid biosynthetic process
YEY1_04825	COG0583	DNA-binding transcription factor activity
YEY1_04830	COG2814	Major facilitator Superfamily
YEY1_04835	COG3021	interspecies interaction between organisms
YEY1_04845	COG0741	lytic transglycosylase activity
YEY1_04845	COG1388	LysM domain
YEY1_04850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YEY1_04855	COG2226	methyltransferase
YEY1_04860	COG0328	RNA-DNA hybrid ribonuclease activity
YEY1_04865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YEY1_04875	COG2113	Glycine betaine
YEY1_04885	COG4176	ABC-type proline glycine betaine transport system permease component
YEY1_04895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YEY1_04905	COG1780	Probably involved in ribonucleotide reductase function
YEY1_04915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YEY1_04925	COG4575	ribosome binding
YEY1_04940	COG2207	Transcriptional regulator
YEY1_04945	COG0477	Major facilitator Superfamily
YEY1_04965	COG1278	Cold shock
YEY1_05000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YEY1_05010	COG1124	(ABC) transporter
YEY1_05025	COG0832	Belongs to the urease beta subunit family
YEY1_05030	COG0804	urea catabolic process
YEY1_05035	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
YEY1_05040	COG0830	nickel cation binding
YEY1_05045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YEY1_05050	COG0829	nickel cation binding
YEY1_05055	COG4413	Urea transporter
YEY1_05060	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YEY1_05070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YEY1_05075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YEY1_05085	COG0667	Aldo Keto reductase
YEY1_05095	COG2133	pyrroloquinoline quinone binding
YEY1_05100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_05105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_05110	COG2723	6-phospho-beta-galactosidase activity
YEY1_05115	COG1447	Phosphotransferase system cellobiose-specific component IIA
YEY1_05120	COG2169	Transcriptional regulator
YEY1_05120	COG1917	Cupin 2, conserved barrel domain protein
YEY1_05125	COG3394	polysaccharide catabolic process
YEY1_05130	COG0659	secondary active sulfate transmembrane transporter activity
YEY1_05140	COG3328	transposase activity
YEY1_05145	COG0582	viral genome integration into host DNA
YEY1_05155	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YEY1_05160	COG2867	negative regulation of translational initiation
YEY1_05170	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YEY1_05175	COG0497	DNA recombination
YEY1_05180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YEY1_05185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YEY1_05190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YEY1_05195	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
YEY1_05225	COG0513	Belongs to the DEAD box helicase family
YEY1_05230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
YEY1_05235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YEY1_05245	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YEY1_05255	COG3086	response to oxidative stress
YEY1_05265	COG0481	GTPase activity
YEY1_05270	COG0681	Belongs to the peptidase S26 family
YEY1_05275	COG0571	ribonuclease III activity
YEY1_05280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YEY1_05285	COG1381	Involved in DNA repair and RecF pathway recombination
YEY1_05290	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YEY1_05295	COG0736	holo-[acyl-carrier-protein] synthase activity
YEY1_05305	COG2610	gluconate transmembrane transporter activity
YEY1_05310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YEY1_05315	COG1737	Transcriptional regulator
YEY1_05325	COG0560	Phosphoserine phosphatase
YEY1_05335	COG0590	tRNA wobble adenosine to inosine editing
YEY1_05340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YEY1_05355	COG2205	protein histidine kinase activity
YEY1_05360	COG3170	Tfp pilus assembly protein FimV
YEY1_05365	COG2204	response regulator
YEY1_05370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YEY1_05370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YEY1_05375	COG0347	Belongs to the P(II) protein family
YEY1_05390	COG1735	metal-dependent hydrolase with the TIM-barrel fold
YEY1_05395	COG3457	Alanine racemase
YEY1_05405	COG2188	Transcriptional regulator
YEY1_05410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YEY1_05410	COG1017	nitric oxide dioxygenase activity
YEY1_05415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YEY1_05420	COG2814	Major facilitator Superfamily
YEY1_05425	COG3711	transcriptional antiterminator
YEY1_05430	COG3683	transport system, periplasmic component
YEY1_05435	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YEY1_05440	COG0483	inositol monophosphate 1-phosphatase activity
YEY1_05445	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
YEY1_05450	COG1959	2 iron, 2 sulfur cluster binding
YEY1_05460	COG0822	iron-sulfur transferase activity
YEY1_05465	COG0316	Belongs to the HesB IscA family
YEY1_05470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YEY1_05475	COG0443	Heat shock 70 kDa protein
YEY1_05480	COG0633	Ferredoxin
YEY1_05485	COG2975	iron-sulfur cluster assembly
YEY1_05510	COG2373	Large extracellular alpha-helical protein
YEY1_05515	COG4953	penicillin-binding protein 1C
YEY1_05530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YEY1_05540	COG1426	Protein conserved in bacteria
YEY1_05545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YEY1_05550	COG0124	histidyl-tRNA synthetase
YEY1_05555	COG2976	Protein conserved in bacteria
YEY1_05560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YEY1_05570	COG1160	GTP binding
YEY1_05585	COG1645	bacterial-type flagellum-dependent swarming motility
YEY1_05590	COG1570	exodeoxyribonuclease VII activity
YEY1_05600	COG0516	GMP reductase activity
YEY1_05600	COG0517	IMP dehydrogenase activity
YEY1_05605	COG0519	Catalyzes the synthesis of GMP from XMP
YEY1_05605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YEY1_05645	COG0351	phosphomethylpyrimidine kinase
YEY1_05665	COG1349	DNA-binding transcription factor activity
YEY1_05670	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_05675	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_05690	COG3730	PTS system glucitol sorbitol-specific
YEY1_05695	COG1597	lipid kinase activity
YEY1_05705	COG3422	double-strand break repair
YEY1_05710	COG0745	RESPONSE REGULATOR receiver
YEY1_05715	COG2205	protein histidine kinase activity
YEY1_05720	COG0477	Major facilitator Superfamily
YEY1_05725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_05735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_05750	COG0443	Heat shock 70 kDa protein
YEY1_05755	COG5001	Diguanylate cyclase
YEY1_05755	COG5002	protein histidine kinase activity
YEY1_05755	COG3447	MASE1 domain protein
YEY1_05765	COG0581	inorganic phosphate transmembrane transporter activity
YEY1_05770	COG0573	inorganic phosphate transmembrane transporter activity
YEY1_05775	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YEY1_05780	COG0248	Ppx GppA phosphatase
YEY1_05790	COG2239	Acts as a magnesium transporter
YEY1_05795	COG5001	Diguanylate cyclase
YEY1_05795	COG3447	MASE1 domain protein
YEY1_05795	COG5002	protein histidine kinase activity
YEY1_05805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YEY1_05810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YEY1_05815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YEY1_05820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YEY1_05825	COG2233	PERMEase
YEY1_05830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YEY1_05835	COG1393	Belongs to the ArsC family
YEY1_05840	COG4783	chaperone-mediated protein folding
YEY1_05845	COG0628	permease
YEY1_05855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YEY1_05860	COG2716	regulation of RNA biosynthetic process
YEY1_05865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YEY1_05870	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YEY1_05880	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YEY1_05885	COG2321	neutral zinc metallopeptidase
YEY1_05890	COG2707	UPF0756 membrane protein
YEY1_05895	COG1444	tRNA N-acetyltransferase activity
YEY1_05910	COG0400	carboxylic ester hydrolase activity
YEY1_05960	COG1876	peptidase activity
YEY1_05965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YEY1_05970	COG1393	Belongs to the ArsC family
YEY1_05985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_05995	COG2197	response regulator
YEY1_06005	COG3062	negative regulation of establishment of protein localization
YEY1_06010	COG0243	molybdopterin cofactor binding
YEY1_06015	COG3043	anaerobic respiration
YEY1_06020	COG3005	denitrification pathway
YEY1_06025	COG0494	nUDIX hydrolase
YEY1_06030	COG0281	malic enzyme
YEY1_06030	COG0280	phosphate acetyltransferase
YEY1_06045	COG3104	oligopeptide transport
YEY1_06055	COG2259	Doxx family
YEY1_06070	COG1560	Kdo2-lipid A biosynthetic process
YEY1_06105	COG0628	permease
YEY1_06135	COG0418	dihydroorotase activity
YEY1_06140	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YEY1_06145	COG1530	ribonuclease E activity
YEY1_06145	COG1530	ribonuclease E activity
YEY1_06155	COG0564	pseudouridine synthase activity
YEY1_06165	COG1399	metal-binding, possibly nucleic acid-binding protein
YEY1_06170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YEY1_06175	COG0416	fatty acid biosynthetic process
YEY1_06180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YEY1_06185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YEY1_06190	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_06200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YEY1_06210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YEY1_06215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YEY1_06220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YEY1_06225	COG0470	DNA polymerase III
YEY1_06230	COG0084	hydrolase, TatD family'
YEY1_06235	COG1263	PTS System
YEY1_06235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_06255	COG0641	radical SAM
YEY1_06270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YEY1_06275	COG0537	adenosine 5'-monophosphoramidase activity
YEY1_06280	COG5633	Lipoprotein
YEY1_06285	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
YEY1_06295	COG1472	Belongs to the glycosyl hydrolase 3 family
YEY1_06300	COG3150	esterase
YEY1_06305	COG1252	NADH dehydrogenase
YEY1_06310	COG3134	Outer membrane lipoprotein
YEY1_06315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YEY1_06320	COG4591	ABC-type transport system involved in lipoprotein release permease component
YEY1_06330	COG4591	ABC-type transport system involved in lipoprotein release permease component
YEY1_06335	COG1940	carbohydrate kinase activity
YEY1_06340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YEY1_06350	COG2850	peptidyl-arginine hydroxylation
YEY1_06360	COG0745	RESPONSE REGULATOR receiver
YEY1_06370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YEY1_06375	COG2915	High frequency lysogenization protein hflD homolog
YEY1_06380	COG0482	sulfurtransferase activity
YEY1_06390	COG1187	pseudouridine synthase activity
YEY1_06395	COG0538	isocitrate dehydrogenase activity
YEY1_06455	COG0840	transmembrane signaling receptor activity
YEY1_06475	COG2873	o-acetylhomoserine
YEY1_06480	COG0702	epimerase
YEY1_06485	COG1733	regulation of RNA biosynthetic process
YEY1_06530	COG2203	Gaf domain
YEY1_06530	COG3706	GGDEF domain
YEY1_06530	COG4251	negative regulation of phosphorylation
YEY1_06530	COG5001	Diguanylate cyclase
YEY1_06550	COG1132	(ABC) transporter
YEY1_06570	COG2207	Transcriptional regulator
YEY1_06575	COG3328	transposase activity
YEY1_06610	COG1113	amino acid transport
YEY1_06625	COG1278	Cold shock
YEY1_06640	COG2226	methyltransferase
YEY1_06650	COG5001	Diguanylate cyclase
YEY1_06650	COG5002	protein histidine kinase activity
YEY1_06650	COG3447	MASE1 domain protein
YEY1_06660	COG1971	Probably functions as a manganese efflux pump
YEY1_06665	COG4811	Protein of unknown function (DUF986)
YEY1_06670	COG3716	PTS system mannose fructose sorbose family IID component
YEY1_06675	COG3715	PTS system
YEY1_06680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_06680	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_06685	COG1253	flavin adenine dinucleotide binding
YEY1_06695	COG1760	l-serine dehydratase
YEY1_06700	COG0494	nUDIX hydrolase
YEY1_06710	COG3140	Belongs to the UPF0181 family
YEY1_06715	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
YEY1_06720	COG0513	Belongs to the DEAD box helicase family
YEY1_06725	COG3141	response to X-ray
YEY1_06740	COG1770	oligopeptidase
YEY1_06745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YEY1_06760	COG1528	Iron-storage protein
YEY1_06765	COG2372	response to copper ion
YEY1_06770	COG1276	copper resistance
YEY1_06780	COG4974	Belongs to the 'phage' integrase family
YEY1_06830	COG3328	transposase activity
YEY1_06840	COG0500	methyltransferase
YEY1_06850	COG3328	transposase activity
YEY1_06865	COG0561	phosphatase activity
YEY1_06870	COG2223	nitrite transmembrane transporter activity
YEY1_06890	COG3493	citrate carrier protein
YEY1_06895	COG4565	transcriptional regulatory protein
YEY1_06900	COG3290	protein histidine kinase activity
YEY1_06905	COG1349	DNA-binding transcription factor activity
YEY1_06910	COG3395	kinase activity
YEY1_06920	COG3622	Belongs to the hyi family
YEY1_06925	COG2066	Belongs to the glutaminase family
YEY1_06940	COG0672	)-iron permease
YEY1_06955	COG1136	(ABC) transporter
YEY1_06955	COG0577	efflux transmembrane transporter activity
YEY1_06965	COG1136	(ABC) transporter
YEY1_06965	COG0577	efflux transmembrane transporter activity
YEY1_06990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YEY1_06995	COG4114	ferric iron reductase
YEY1_07000	COG0006	proline dipeptidase activity
YEY1_07010	COG1649	PFAM Uncharacterised BCR, COG1649
YEY1_07010	COG0726	polysaccharide deacetylase
YEY1_07015	COG1215	transferase activity, transferring glycosyl groups
YEY1_07020	COG3658	cytochrome
YEY1_07035	COG1702	phosphate starvation-inducible protein PhoH
YEY1_07045	COG0018	arginyl-trna synthetase
YEY1_07050	COG3102	Protein conserved in bacteria
YEY1_07055	COG3142	Participates in the control of copper homeostasis
YEY1_07075	COG0668	transmembrane transport
YEY1_07080	COG0625	glutathione transferase activity
YEY1_07105	COG5001	Diguanylate cyclase
YEY1_07150	COG3008	intermembrane lipid transfer
YEY1_07155	COG2995	paraquat-inducible protein a
YEY1_07160	COG1956	GAF domain-containing protein
YEY1_07170	COG0793	Belongs to the peptidase S41A family
YEY1_07175	COG0501	Belongs to the peptidase M48B family
YEY1_07185	COG2814	Major facilitator Superfamily
YEY1_07190	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_07200	COG3023	N-Acetylmuramoyl-L-alanine amidase
YEY1_07215	COG1988	membrane-bound metal-dependent
YEY1_07225	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YEY1_07230	COG1653	transport
YEY1_07235	COG3842	ATPase activity
YEY1_07240	COG0395	ABC-type sugar transport system, permease component
YEY1_07245	COG1175	transmembrane transport
YEY1_07255	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_07260	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
YEY1_07265	COG1917	Cupin 2, conserved barrel domain protein
YEY1_07270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_07280	COG0583	DNA-binding transcription factor activity
YEY1_07285	COG0427	acetyl-CoA hydrolase
YEY1_07290	COG1024	Enoyl-CoA hydratase
YEY1_07295	COG1703	isobutyryl-CoA mutase activity
YEY1_07300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YEY1_07300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YEY1_07315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_07320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_07325	COG1121	(ABC) transporter
YEY1_07330	COG0803	Belongs to the bacterial solute-binding protein 9 family
YEY1_07365	COG1811	Na channel or pump
YEY1_07370	COG4249	Peptidase C14 caspase catalytic subunit p20
YEY1_07375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YEY1_07380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
YEY1_07385	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YEY1_07390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YEY1_07395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YEY1_07405	COG0776	regulation of translation
YEY1_07410	COG2314	TM2 domain
YEY1_07420	COG4139	cobalamin transport
YEY1_07425	COG0386	Belongs to the glutathione peroxidase family
YEY1_07430	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YEY1_07435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YEY1_07440	COG0463	Glycosyl transferase, family 2
YEY1_07445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YEY1_07445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_07450	COG0726	polysaccharide deacetylase
YEY1_07455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YEY1_07460	COG2076	Multidrug Resistance protein
YEY1_07465	COG2076	Multidrug Resistance protein
YEY1_07470	COG0791	NLP P60 protein
YEY1_07475	COG0095	Lipoate-protein ligase
YEY1_07485	COG4558	Periplasmic binding protein
YEY1_07490	COG3720	iron ion transport
YEY1_07510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YEY1_07515	COG0574	Belongs to the PEP-utilizing enzyme family
YEY1_07515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YEY1_07525	COG0628	permease
YEY1_07530	COG0277	FAD linked oxidase domain protein
YEY1_07530	COG0247	lactate metabolic process
YEY1_07540	COG2050	protein possibly involved in aromatic compounds catabolism
YEY1_07550	COG0316	Belongs to the HesB IscA family
YEY1_07555	COG0719	Fe-S assembly protein
YEY1_07560	COG0396	ATPase activity
YEY1_07565	COG0719	Fe-S assembly protein
YEY1_07575	COG2166	iron-sulfur cluster assembly
YEY1_07580	COG1376	ErfK ybiS ycfS ynhG family protein
YEY1_07580	COG1388	LysM domain
YEY1_07585	COG4238	major outer membrane lipoprotein
YEY1_07605	COG0534	Mate efflux family protein
YEY1_07610	COG0307	riboflavin synthase, alpha
YEY1_07615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YEY1_07620	COG2814	Major facilitator Superfamily
YEY1_07625	COG0583	DNA-binding transcription factor activity
YEY1_07630	COG1609	Transcriptional regulator
YEY1_07640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YEY1_07645	COG0791	NLP P60 protein
YEY1_07650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YEY1_07660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YEY1_07675	COG0346	lactoylglutathione lyase activity
YEY1_07680	COG1902	pentaerythritol trinitrate reductase activity
YEY1_07685	COG1309	transcriptional regulator
YEY1_07690	COG2194	sulfuric ester hydrolase activity
YEY1_07695	COG3313	Fe-S protein
YEY1_07700	COG4989	oxidoreductase activity
YEY1_07705	COG1289	transmembrane transporter activity
YEY1_07710	COG1566	PFAM secretion protein HlyD family protein
YEY1_07720	COG1846	Transcriptional regulator
YEY1_07725	COG3133	Outer membrane lipoprotein
YEY1_07730	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YEY1_07735	COG3895	Periplasmic Protein
YEY1_07740	COG0259	pyridoxamine-phosphate oxidase activity
YEY1_07745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YEY1_07755	COG0625	glutathione transferase activity
YEY1_07775	COG3104	oligopeptide transport
YEY1_07785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YEY1_07785	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YEY1_07795	COG4172	Belongs to the ABC transporter superfamily
YEY1_07805	COG4171	peptide transport system, permease
YEY1_07810	COG4168	peptide transport system, permease
YEY1_07815	COG4166	transmembrane transport
YEY1_07835	COG0235	Class ii aldolase
YEY1_07845	COG1349	DNA-binding transcription factor activity
YEY1_07850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YEY1_07855	COG2879	small protein
YEY1_07860	COG1966	Carbon starvation protein
YEY1_07865	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YEY1_07875	COG0243	molybdopterin cofactor binding
YEY1_07895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YEY1_07905	COG4659	FMN binding
YEY1_07910	COG4658	electron transport chain
YEY1_07915	COG2207	Transcriptional regulator
YEY1_07915	COG3708	Transcriptional regulator
YEY1_07925	COG4656	Part of a membrane complex involved in electron transport
YEY1_07935	COG4657	Part of a membrane complex involved in electron transport
YEY1_07945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
YEY1_07955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_07965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YEY1_07970	COG2160	L-arabinose isomerase activity
YEY1_07980	COG1879	ABC-type sugar transport system periplasmic component
YEY1_07990	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_08000	COG0673	inositol 2-dehydrogenase activity
YEY1_08005	COG0385	Bile acid
YEY1_08010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YEY1_08015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YEY1_08035	COG5339	Protein conserved in bacteria
YEY1_08045	COG0114	fumarate hydratase activity
YEY1_08080	COG2814	Major facilitator Superfamily
YEY1_08085	COG0583	DNA-binding transcription factor activity
YEY1_08090	COG1940	carbohydrate kinase activity
YEY1_08095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YEY1_08125	COG1742	UPF0060 membrane protein
YEY1_08130	COG4221	oxidoreductase activity
YEY1_08235	COG0625	glutathione transferase activity
YEY1_08265	COG1522	sequence-specific DNA binding
YEY1_08305	COG3177	Filamentation induced by cAMP protein fic
YEY1_08315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YEY1_08325	COG0483	inositol monophosphate 1-phosphatase activity
YEY1_08360	COG3023	N-Acetylmuramoyl-L-alanine amidase
YEY1_08375	COG0028	Belongs to the TPP enzyme family
YEY1_08380	COG0440	acetolactate synthase activity
YEY1_08385	COG1011	Hydrolase
YEY1_08405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_08415	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_08420	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
YEY1_08435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YEY1_08440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YEY1_08445	COG0589	response to stress
YEY1_08450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YEY1_08455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YEY1_08470	COG0531	amino acid
YEY1_08480	COG0745	RESPONSE REGULATOR receiver
YEY1_08485	COG2205	protein histidine kinase activity
YEY1_08500	COG3591	Belongs to the peptidase S1B family
YEY1_08515	COG1643	Atp-dependent helicase
YEY1_08520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YEY1_08525	COG3784	Protein of unknown function (DUF1318)
YEY1_08535	COG2911	Protein conserved in bacteria
YEY1_08540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YEY1_08545	COG3042	response to heat
YEY1_08550	COG1285	pathogenesis
YEY1_08560	COG1013	pyruvate-flavodoxin oxidoreductase activity
YEY1_08560	COG0674	pyruvate-flavodoxin oxidoreductase activity
YEY1_08560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_08560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YEY1_08565	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_08570	COG0037	tRNA processing
YEY1_08575	COG0598	Magnesium transport protein CorA
YEY1_08580	COG4166	transmembrane transport
YEY1_08585	COG2866	Carboxypeptidase
YEY1_08590	COG4948	Mandelate Racemase Muconate Lactonizing
YEY1_08595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YEY1_08620	COG3768	UPF0283 membrane protein
YEY1_08625	COG3106	COG3106 Predicted ATPase
YEY1_08635	COG1983	PspC domain protein
YEY1_08645	COG1842	Phage shock protein A
YEY1_08650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YEY1_08675	COG0023	Translation Initiation Factor
YEY1_08680	COG0284	orotidine-5'-phosphate decarboxylase activity
YEY1_08695	COG1396	sequence-specific DNA binding
YEY1_08705	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YEY1_08710	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YEY1_08715	COG0671	phosphoesterase, PA-phosphatase related
YEY1_08720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YEY1_08735	COG0583	DNA-binding transcription factor activity
YEY1_08740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YEY1_08750	COG0616	signal peptide processing
YEY1_08755	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_08760	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
YEY1_08770	COG1187	pseudouridine synthase activity
YEY1_08775	COG0009	L-threonylcarbamoyladenylate synthase
YEY1_08780	COG0613	PHP domain protein
YEY1_08795	COG0512	Glutamine amidotransferase of anthranilate synthase
YEY1_08805	COG0135	phosphoribosylanthranilate isomerase activity
YEY1_08805	COG0134	indole-3-glycerol-phosphate synthase activity
YEY1_08810	COG0133	tryptophan synthase activity
YEY1_08815	COG0159	tryptophan synthase activity
YEY1_08825	COG3047	cAMP biosynthetic process
YEY1_08845	COG2917	probably involved in intracellular septation
YEY1_08850	COG1607	acyl-coa hydrolase
YEY1_08855	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YEY1_08860	COG2350	Protein conserved in bacteria
YEY1_08885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YEY1_08890	COG3099	Belongs to the UPF0263 family
YEY1_08900	COG0444	Belongs to the ABC transporter superfamily
YEY1_08905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YEY1_08925	COG2095	MarC family integral membrane protein
YEY1_08935	COG1012	belongs to the aldehyde dehydrogenase family
YEY1_08935	COG1454	alcohol dehydrogenase
YEY1_08940	COG1435	thymidine kinase activity
YEY1_08950	COG2916	Histone family protein nucleoid-structuring protein H-NS
YEY1_08965	COG1752	Esterase of the alpha-beta hydrolase superfamily
YEY1_08975	COG3012	SEC-C Motif Domain Protein
YEY1_08980	COG0788	formyltetrahydrofolate deformylase activity
YEY1_08995	COG0583	DNA-binding transcription factor activity
YEY1_09000	COG0708	Exodeoxyribonuclease III
YEY1_09005	COG0494	nUDIX hydrolase
YEY1_09015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YEY1_09025	COG0778	Nitroreductase
YEY1_09030	COG0616	signal peptide processing
YEY1_09035	COG0252	asparaginase activity
YEY1_09040	COG1335	isochorismatase
YEY1_09050	COG3139	Protein of unknown function (DUF1315)
YEY1_09055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YEY1_09070	COG3713	MltA-interacting MipA family protein
YEY1_09080	COG2766	serine protein kinase
YEY1_09085	COG2718	Belongs to the UPF0229 family
YEY1_09100	COG0583	DNA-binding transcription factor activity
YEY1_09110	COG2202	Pas domain
YEY1_09110	COG2199	diguanylate cyclase activity
YEY1_09110	COG2200	EAL domain
YEY1_09115	COG2814	Major facilitator Superfamily
YEY1_09120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YEY1_09130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YEY1_09135	COG2719	SpoVR family
YEY1_09140	COG2186	Transcriptional regulator
YEY1_09145	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YEY1_09150	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YEY1_09170	COG2983	Belongs to the UPF0260 family
YEY1_09175	COG0179	Fumarylacetoacetate (FAA) hydrolase
YEY1_09180	COG2951	lytic endotransglycosylase activity
YEY1_09185	COG3100	YcgL domain-containing protein
YEY1_09195	COG0850	regulation of cytokinetic process
YEY1_09200	COG2894	cell division
YEY1_09205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YEY1_09210	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YEY1_09215	COG0318	PFAM AMP-dependent synthetase and ligase
YEY1_09220	COG3065	identical protein binding
YEY1_09230	COG1199	ATP-dependent helicase activity
YEY1_09235	COG0251	oxidation-reduction process
YEY1_09240	COG2076	Multidrug Resistance protein
YEY1_09245	COG2076	Multidrug Resistance protein
YEY1_09255	COG0800	Aldolase
YEY1_09260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YEY1_09265	COG1737	Transcriptional regulator
YEY1_09270	COG0469	pyruvate kinase activity
YEY1_09280	COG1560	Kdo2-lipid A biosynthetic process
YEY1_09285	COG0739	heme binding
YEY1_09290	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YEY1_09295	COG1121	(ABC) transporter
YEY1_09300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_09305	COG3104	oligopeptide transport
YEY1_09310	COG2255	four-way junction helicase activity
YEY1_09315	COG0632	four-way junction helicase activity
YEY1_09320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YEY1_09330	COG0217	transcriptional regulatory protein
YEY1_09335	COG0494	nUDIX hydrolase
YEY1_09340	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YEY1_09350	COG1335	isochorismatase
YEY1_09355	COG1801	Protein of unknown function DUF72
YEY1_09360	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YEY1_09365	COG2226	methyltransferase
YEY1_09370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YEY1_09385	COG1349	DNA-binding transcription factor activity
YEY1_09395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_09405	COG3716	PTS system mannose fructose sorbose family IID component
YEY1_09410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_09415	COG2222	sugar isomerase
YEY1_09425	COG4942	peptidase
YEY1_09450	COG3443	Belongs to the bacterial solute-binding protein 9 family
YEY1_09460	COG0402	S-adenosylhomocysteine deaminase activity
YEY1_09470	COG1228	amidohydrolase
YEY1_09500	COG2988	succinylglutamate desuccinylase activity
YEY1_09505	COG3724	N-succinylarginine dihydrolase activity
YEY1_09515	COG3138	arginine N-succinyltransferase
YEY1_09520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YEY1_09525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_09530	COG1271	oxidase subunit
YEY1_09535	COG1294	oxidase, subunit
YEY1_09545	COG3850	Histidine kinase
YEY1_09550	COG0583	DNA-binding transcription factor activity
YEY1_09565	COG2814	Major facilitator Superfamily
YEY1_09575	COG0387	Pfam Sodium calcium exchanger
YEY1_09580	COG0728	peptidoglycan biosynthetic process
YEY1_09585	COG0673	inositol 2-dehydrogenase activity
YEY1_09595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YEY1_09610	COG0477	Major facilitator Superfamily
YEY1_09620	COG3381	protein complex oligomerization
YEY1_09625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
YEY1_09630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YEY1_09650	COG3706	GGDEF domain
YEY1_09655	COG0659	secondary active sulfate transmembrane transporter activity
YEY1_09660	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YEY1_09665	COG2912	Transglutaminase-like superfamily
YEY1_09670	COG3094	Invasion gene expression up-regulator, SirB
YEY1_09675	COG2890	protein-(glutamine-N5) methyltransferase activity
YEY1_09680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YEY1_09685	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YEY1_09690	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
YEY1_09700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YEY1_09715	COG0193	aminoacyl-tRNA hydrolase activity
YEY1_09725	COG0012	GTP binding
YEY1_09740	COG2979	Protein of unknown function (DUF533)
YEY1_09745	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YEY1_09750	COG3772	lysozyme
YEY1_09890	COG3041	Addiction module toxin RelE StbE family
YEY1_09895	COG3077	Addiction module antitoxin, RelB DinJ family
YEY1_09935	COG3328	transposase activity
YEY1_09965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YEY1_09970	COG0322	excinuclease ABC activity
YEY1_09975	COG2197	response regulator
YEY1_09985	COG3136	membrane protein required for alginate biosynthesis
YEY1_09995	COG0366	Alpha amylase catalytic
YEY1_10010	COG2226	methyltransferase
YEY1_10020	COG0582	viral genome integration into host DNA
YEY1_10030	COG1113	amino acid transport
YEY1_10035	COG1309	transcriptional regulator
YEY1_10045	COG1335	isochorismatase
YEY1_10050	COG0251	oxidation-reduction process
YEY1_10055	COG2267	carboxylic ester hydrolase activity
YEY1_10060	COG0778	Nitroreductase
YEY1_10065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YEY1_10080	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
YEY1_10090	COG0655	NAD(P)H dehydrogenase (quinone) activity
YEY1_10115	COG3157	Type VI secretion system effector, Hcp
YEY1_10140	COG0506	proline dehydrogenase activity
YEY1_10140	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YEY1_10140	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YEY1_10170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YEY1_10180	COG1191	sigma factor activity
YEY1_10215	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YEY1_10220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YEY1_10250	COG0582	viral genome integration into host DNA
YEY1_10255	COG1677	Flagellar hook-basal body complex protein FliE
YEY1_10265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YEY1_10270	COG1317	bacterial-type flagellum organization
YEY1_10280	COG2882	bacterial-type flagellum organization
YEY1_10290	COG1580	Controls the rotational direction of flagella during chemotaxis
YEY1_10310	COG1338	Plays a role in the flagellum-specific transport system
YEY1_10330	COG1256	bacterial-type flagellum assembly
YEY1_10350	COG4786	Flagellar basal body rod
YEY1_10360	COG1749	Flagellar hook protein flgE
YEY1_10370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YEY1_10375	COG1558	bacterial-type flagellum-dependent cell motility
YEY1_10380	COG1815	bacterial-type flagellum-dependent cell motility
YEY1_10390	COG2747	anti-sigma28 factor FlgM
YEY1_10395	COG3418	PFAM FlgN family protein
YEY1_10415	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YEY1_10420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YEY1_10430	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YEY1_10435	COG0745	RESPONSE REGULATOR receiver
YEY1_10445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YEY1_10450	COG0840	transmembrane signaling receptor activity
YEY1_10455	COG0840	transmembrane signaling receptor activity
YEY1_10465	COG0835	chemotaxis
YEY1_10470	COG0643	Histidine kinase
YEY1_10470	COG2198	Histidine kinase
YEY1_10475	COG1360	Flagellar Motor Protein
YEY1_10495	COG0589	response to stress
YEY1_10500	COG2130	NADP-dependent
YEY1_10510	COG1285	pathogenesis
YEY1_10525	COG0840	transmembrane signaling receptor activity
YEY1_10535	COG1278	Cold shock
YEY1_10540	COG1609	Transcriptional regulator
YEY1_10545	COG3250	beta-galactosidase activity
YEY1_10550	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_10550	COG3321	synthase
YEY1_10550	COG0604	alcohol dehydrogenase
YEY1_10580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
YEY1_10590	COG3263	regulation of cellular component size
YEY1_10600	COG3916	Acyl-homoserine-lactone synthase
YEY1_10605	COG2771	luxR family
YEY1_10610	COG4235	cytochrome complex assembly
YEY1_10615	COG3088	subunit of a heme lyase
YEY1_10620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YEY1_10625	COG1138	Cytochrome C-type biogenesis protein
YEY1_10630	COG3301	Polysulphide reductase, NrfD
YEY1_10635	COG0437	4 iron, 4 sulfur cluster binding
YEY1_10640	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
YEY1_10660	COG2920	part of a sulfur-relay system
YEY1_10665	COG1254	Belongs to the acylphosphatase family
YEY1_10680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YEY1_10685	COG3785	DNA binding
YEY1_10690	COG1832	CoA-binding protein
YEY1_10695	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YEY1_10700	COG1803	Methylglyoxal synthase
YEY1_10705	COG0210	DNA helicase
YEY1_10710	COG3304	Inner membrane component domain
YEY1_10715	COG1289	transmembrane transporter activity
YEY1_10720	COG3070	regulator of competence-specific genes
YEY1_10725	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
YEY1_10730	COG2885	chlorophyll binding
YEY1_10730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YEY1_10735	COG3120	sequence-specific DNA binding
YEY1_10740	COG1067	ATP-dependent peptidase activity
YEY1_10745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YEY1_10755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YEY1_10760	COG3130	regulation of translation
YEY1_10765	COG3009	Protein conserved in bacteria
YEY1_10770	COG3008	intermembrane lipid transfer
YEY1_10770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YEY1_10775	COG2995	paraquat-inducible protein a
YEY1_10780	COG0488	(ABC) transporter
YEY1_10785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YEY1_10785	COG0116	Belongs to the methyltransferase superfamily
YEY1_10790	COG0633	Ferredoxin
YEY1_10790	COG3217	Mosc domain protein beta barrel domain protein
YEY1_10800	COG0167	dihydroorotate dehydrogenase activity
YEY1_10805	COG0308	aminopeptidase N
YEY1_10815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YEY1_10820	COG0017	Asparaginyl-tRNA synthetase
YEY1_10830	COG1448	Aminotransferase
YEY1_10835	COG2200	EAL domain
YEY1_10840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YEY1_10845	COG3108	Peptidase M15
YEY1_10850	COG2989	Protein conserved in bacteria
YEY1_10855	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
YEY1_10860	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YEY1_10865	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YEY1_10870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YEY1_10875	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YEY1_10880	COG3173	Aminoglycoside phosphotransferase
YEY1_10885	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
YEY1_10890	COG2835	tetraacyldisaccharide 4'-kinase activity
YEY1_10900	COG1278	Cold shock
YEY1_10905	COG1278	Cold shock
YEY1_10915	COG5383	Protein conserved in bacteria
YEY1_10920	COG1663	tetraacyldisaccharide 4'-kinase activity
YEY1_10930	COG2333	competence protein COMEC
YEY1_10930	COG0658	competence protein
YEY1_10935	COG0776	regulation of translation
YEY1_10940	COG0539	negative regulation of cytoplasmic translation
YEY1_10945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YEY1_10950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YEY1_10955	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YEY1_10960	COG2323	membrane
YEY1_10965	COG0252	asparaginase activity
YEY1_10970	COG1944	ATP diphosphatase activity
YEY1_10985	COG2116	formate transmembrane transporter activity
YEY1_10990	COG1882	Formate acetyltransferase
YEY1_10995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YEY1_11000	COG2814	Major facilitator Superfamily
YEY1_11005	COG3328	transposase activity
YEY1_11015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YEY1_11020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YEY1_11025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
YEY1_11030	COG1674	ftsk spoiiie
YEY1_11030	COG3107	peptidoglycan biosynthetic process
YEY1_11035	COG1522	sequence-specific DNA binding
YEY1_11040	COG0492	ferredoxin-NADP+ reductase activity
YEY1_11050	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YEY1_11055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YEY1_11060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YEY1_11065	COG0542	response to heat
YEY1_11070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YEY1_11075	COG1278	Cold shock
YEY1_11085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_11090	COG2990	Protein conserved in bacteria
YEY1_11095	COG3593	DNA synthesis involved in DNA repair
YEY1_11100	COG2431	L-lysine efflux transmembrane transporter activity
YEY1_11105	COG1151	hydroxylamine reductase activity
YEY1_11110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YEY1_11115	COG0028	Belongs to the TPP enzyme family
YEY1_11125	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YEY1_11130	COG0702	epimerase
YEY1_11135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_11150	COG1126	abc transporter atp-binding protein
YEY1_11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_11160	COG4215	(ABC) transporter
YEY1_11165	COG4160	amino acid transport
YEY1_11170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_11175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YEY1_11185	COG1177	transmembrane transport
YEY1_11190	COG1176	ABC-type spermidine putrescine transport system, permease component I
YEY1_11195	COG3842	ATPase activity
YEY1_11200	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YEY1_11215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YEY1_11220	COG2985	domain, Protein
YEY1_11220	COG0569	domain protein
YEY1_11230	COG0671	phosphoesterase, PA-phosphatase related
YEY1_11235	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YEY1_11240	COG1349	DNA-binding transcription factor activity
YEY1_11245	COG0814	amino acid
YEY1_11250	COG1760	l-serine dehydratase
YEY1_11265	COG1686	Belongs to the peptidase S11 family
YEY1_11275	COG0626	cystathionine gamma-synthase activity
YEY1_11280	COG2011	ABC-type metal ion transport system permease component
YEY1_11305	COG0625	glutathione transferase activity
YEY1_11315	COG4771	TonB-dependent receptor
YEY1_11325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YEY1_11330	COG0833	amino acid
YEY1_11335	COG0583	DNA-binding transcription factor activity
YEY1_11350	COG2855	membrane
YEY1_11360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
YEY1_11385	COG3710	Transcriptional regulator
YEY1_11390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YEY1_11390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YEY1_11390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YEY1_11395	COG1105	Belongs to the carbohydrate kinase PfkB family
YEY1_11410	COG3005	denitrification pathway
YEY1_11415	COG0243	molybdopterin cofactor binding
YEY1_11430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YEY1_11435	COG1312	Catalyzes the dehydration of D-mannonate
YEY1_11445	COG0246	Mannitol dehydrogenase
YEY1_11450	COG2186	Transcriptional regulator
YEY1_11460	COG0523	cobalamin synthesis protein
YEY1_11465	COG0671	phosphoesterase, PA-phosphatase related
YEY1_11470	COG0791	NLP P60 protein
YEY1_11480	COG2200	EAL domain
YEY1_11485	COG4166	transmembrane transport
YEY1_11490	COG4174	ABC transporter (Permease)
YEY1_11495	COG4239	(ABC) transporter, permease
YEY1_11500	COG4172	Belongs to the ABC transporter superfamily
YEY1_11510	COG2814	Major facilitator Superfamily
YEY1_11515	COG1187	pseudouridine synthase activity
YEY1_11520	COG1061	Type III restriction enzyme res subunit
YEY1_11525	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YEY1_11530	COG3081	Nucleoid-associated protein
YEY1_11535	COG3082	Protein of unknown function (DUF1414)
YEY1_11565	COG3328	transposase activity
YEY1_11575	COG2723	6-phospho-beta-galactosidase activity
YEY1_11580	COG1263	PTS System
YEY1_11580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_11580	COG2190	(PTS) system
YEY1_11585	COG1737	Transcriptional regulator
YEY1_11630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YEY1_11645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YEY1_11655	COG2223	nitrite transmembrane transporter activity
YEY1_11660	COG2198	Histidine kinase
YEY1_11660	COG0642	Histidine kinase
YEY1_11665	COG2197	response regulator
YEY1_11670	COG2205	protein histidine kinase activity
YEY1_11670	COG0784	Response regulator, receiver
YEY1_11680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YEY1_11685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YEY1_11695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YEY1_11700	COG4574	serine-type endopeptidase inhibitor activity
YEY1_11730	COG0814	amino acid
YEY1_11750	COG1441	menaquinone biosynthetic process
YEY1_11755	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YEY1_11760	COG0596	Alpha beta hydrolase
YEY1_11765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
YEY1_11770	COG1169	isochorismate synthase
YEY1_11775	COG4575	ribosome binding
YEY1_11780	COG0129	dihydroxy-acid dehydratase activity
YEY1_11785	COG4702	Belongs to the UPF0303 family
YEY1_11795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YEY1_11800	COG1609	Transcriptional regulator
YEY1_11810	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_11815	COG3265	gluconokinase activity
YEY1_11835	COG1007	ATP synthesis coupled electron transport
YEY1_11840	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_11845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YEY1_11850	COG0713	ATP synthesis coupled electron transport
YEY1_11855	COG0839	Belongs to the complex I subunit 6 family
YEY1_11860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_11865	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YEY1_11870	COG1034	ATP synthesis coupled electron transport
YEY1_11880	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
YEY1_11885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_11885	COG0649	NAD binding
YEY1_11890	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_11895	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_11900	COG0583	DNA-binding transcription factor activity
YEY1_11905	COG0436	Aminotransferase
YEY1_11915	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
YEY1_11920	COG0471	metal ion transport
YEY1_11920	COG0490	domain, Protein
YEY1_11930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_11935	COG3013	Belongs to the UPF0304 family
YEY1_11940	COG3092	negative regulation of chromosome organization
YEY1_11950	COG0857	belongs to the CobB CobQ family
YEY1_11950	COG0280	phosphate acetyltransferase
YEY1_11955	COG1609	Transcriptional regulator
YEY1_11960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_11970	COG3037	sugar-specific permease SgaT UlaA
YEY1_11985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YEY1_11990	COG0622	Phosphoesterase
YEY1_12000	COG1090	epimerase
YEY1_12015	COG4598	ABC transporter
YEY1_12020	COG4160	amino acid transport
YEY1_12025	COG4215	(ABC) transporter
YEY1_12030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_12035	COG0163	prenyltransferase activity
YEY1_12040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YEY1_12045	COG1286	toxin biosynthetic process
YEY1_12050	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YEY1_12055	COG0285	dihydrofolate synthase activity
YEY1_12060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YEY1_12065	COG0586	Pfam SNARE associated Golgi protein
YEY1_12075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YEY1_12080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YEY1_12090	COG0697	spore germination
YEY1_12095	COG0697	spore germination
YEY1_12100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_12105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YEY1_12130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YEY1_12140	COG1609	Transcriptional regulator
YEY1_12150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_12155	COG2723	6-phospho-beta-galactosidase activity
YEY1_12160	COG1447	Phosphotransferase system cellobiose-specific component IIA
YEY1_12170	COG1794	racemase activity, acting on amino acids and derivatives
YEY1_12180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YEY1_12185	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YEY1_12185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YEY1_12195	COG3101	peptidyl-lysine hydroxylation
YEY1_12205	COG0730	response to heat
YEY1_12210	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
YEY1_12215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YEY1_12220	COG2890	protein-(glutamine-N5) methyltransferase activity
YEY1_12225	COG2840	Smr protein MutS2
YEY1_12230	COG2062	phosphohistidine phosphatase, SixA
YEY1_12240	COG1250	3-hydroxyacyl-CoA dehydrogenase
YEY1_12240	COG1024	Enoyl-CoA hydratase
YEY1_12245	COG0183	Belongs to the thiolase family
YEY1_12250	COG3691	Protein conserved in bacteria
YEY1_12265	COG4235	cytochrome complex assembly
YEY1_12265	COG3088	subunit of a heme lyase
YEY1_12275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YEY1_12280	COG1138	Cytochrome C-type biogenesis protein
YEY1_12285	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
YEY1_12290	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YEY1_12295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YEY1_12300	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YEY1_12310	COG2116	formate transmembrane transporter activity
YEY1_12330	COG2824	Alkylphosphonate utilization operon protein PhnA
YEY1_12335	COG1695	Transcriptional regulator
YEY1_12345	COG2723	6-phospho-beta-galactosidase activity
YEY1_12350	COG1263	PTS System
YEY1_12350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_12355	COG1609	Transcriptional regulator
YEY1_12360	COG2353	YceI-like domain
YEY1_12370	COG0657	acetylesterase activity
YEY1_12370	COG2755	lipolytic protein G-D-S-L family
YEY1_12390	COG1127	ABC transporter
YEY1_12395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YEY1_12415	COG0531	amino acid
YEY1_12420	COG2951	lytic endotransglycosylase activity
YEY1_12440	COG1280	lysine exporter protein (LysE YggA)
YEY1_12450	COG1598	PFAM Uncharacterised protein family UPF0150
YEY1_12460	COG3038	cytochrome b561
YEY1_12465	COG0436	Aminotransferase
YEY1_12480	COG3275	phosphorelay sensor kinase activity
YEY1_12485	COG3279	Response regulator of the LytR AlgR family
YEY1_12490	COG2223	nitrite transmembrane transporter activity
YEY1_12500	COG0837	glucose binding
YEY1_12515	COG3961	Belongs to the TPP enzyme family
YEY1_12520	COG0667	Aldo Keto reductase
YEY1_12530	COG1914	H( )-stimulated, divalent metal cation uptake system
YEY1_12535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YEY1_12560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YEY1_12590	COG3530	Putative quorum-sensing-regulated virulence factor
YEY1_12595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YEY1_12610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YEY1_12615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_12620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YEY1_12625	COG2190	(PTS) system
YEY1_12630	COG2205	protein histidine kinase activity
YEY1_12635	COG0745	RESPONSE REGULATOR receiver
YEY1_12640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_12660	COG4208	sulfate ABC transporter
YEY1_12665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YEY1_12670	COG4150	thiosulfate binding
YEY1_12690	COG1737	Transcriptional regulator
YEY1_12695	COG2731	YhcH YjgK YiaL family protein
YEY1_12710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YEY1_12725	COG2837	iron assimilation
YEY1_12735	COG3111	PFAM Bacterial OB fold (BOF) protein
YEY1_12740	COG0456	acetyltransferase
YEY1_12745	COG0408	coproporphyrinogen oxidase activity
YEY1_12750	COG1671	Belongs to the UPF0178 family
YEY1_12770	COG2943	transferase activity, transferring hexosyl groups
YEY1_12775	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YEY1_12795	COG3121	Chaperone
YEY1_12820	COG1070	Carbohydrate kinase
YEY1_12825	COG1070	Carbohydrate kinase
YEY1_12835	COG3228	Belongs to the MtfA family
YEY1_12845	COG0582	viral genome integration into host DNA
YEY1_12850	COG0583	DNA-binding transcription factor activity
YEY1_12855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
YEY1_12880	COG2003	Belongs to the UPF0758 family
YEY1_12930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_12930	COG2205	protein histidine kinase activity
YEY1_12955	COG3121	Chaperone
YEY1_12975	COG3122	Protein conserved in bacteria
YEY1_12980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_12980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_12985	COG2814	Major facilitator Superfamily
YEY1_13005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YEY1_13020	COG0471	metal ion transport
YEY1_13030	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
YEY1_13030	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
YEY1_13035	COG3051	citrate lyase alpha subunit
YEY1_13040	COG2301	Belongs to the HpcH HpaI aldolase family
YEY1_13045	COG3052	prosthetic group binding
YEY1_13050	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
YEY1_13055	COG3290	protein histidine kinase activity
YEY1_13060	COG4565	transcriptional regulatory protein
YEY1_13075	COG2271	Major facilitator Superfamily
YEY1_13080	COG1840	ABC-type Fe3 transport system, periplasmic component
YEY1_13090	COG3842	ATPase activity
YEY1_13115	COG4221	oxidoreductase activity
YEY1_13125	COG0784	Response regulator, receiver
YEY1_13125	COG0835	chemotaxis
YEY1_13135	COG1349	DNA-binding transcription factor activity
YEY1_13140	COG0561	phosphatase activity
YEY1_13145	COG0352	thiamine-phosphate diphosphorylase activity
YEY1_13155	COG0534	Mate efflux family protein
YEY1_13160	COG0137	argininosuccinate synthase activity
YEY1_13185	COG3501	Rhs element vgr protein
YEY1_13230	COG3188	usher protein
YEY1_13235	COG3121	Chaperone
YEY1_13300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YEY1_13320	COG1492	cobalamin metabolic process
YEY1_13370	COG2875	Belongs to the precorrin methyltransferase family
YEY1_13380	COG2241	protein methyltransferase activity
YEY1_13385	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
YEY1_13395	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YEY1_13415	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
YEY1_13450	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
YEY1_13480	COG1012	belongs to the aldehyde dehydrogenase family
YEY1_13490	COG4656	Part of a membrane complex involved in electron transport
YEY1_13500	COG4810	utilization protein
YEY1_13510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YEY1_13520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YEY1_13535	COG1879	ABC-type sugar transport system periplasmic component
YEY1_13545	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_13555	COG2926	Belongs to the UPF0265 family
YEY1_13560	COG1289	transmembrane transporter activity
YEY1_13565	COG3320	Male sterility
YEY1_13565	COG1022	Amp-dependent synthetase and ligase
YEY1_13570	COG2925	Exonuclease
YEY1_13575	COG0531	amino acid
YEY1_13585	COG0371	Dehydrogenase
YEY1_13595	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_13600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_13610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YEY1_13620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YEY1_13625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YEY1_13625	COG0131	Imidazoleglycerol-phosphate dehydratase
YEY1_13630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YEY1_13635	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YEY1_13640	COG0107	imidazoleglycerol-phosphate synthase activity
YEY1_13645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YEY1_13645	COG0140	phosphoribosyl-ATP diphosphatase activity
YEY1_13650	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
YEY1_13660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YEY1_13665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YEY1_13680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YEY1_13680	COG0473	3-isopropylmalate dehydrogenase activity
YEY1_13705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_13750	COG1253	flavin adenine dinucleotide binding
YEY1_13755	COG3069	C4-dicarboxylate transmembrane transporter activity
YEY1_13760	COG2982	Protein involved in outer membrane biogenesis
YEY1_13770	COG0572	uridine kinase
YEY1_13775	COG0489	protein tyrosine kinase activity
YEY1_13780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YEY1_13780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YEY1_13800	COG2814	Major facilitator Superfamily
YEY1_13805	COG1380	Effector of murein hydrolase LrgA
YEY1_13810	COG1346	cytolysis
YEY1_13825	COG0281	malic enzyme
YEY1_13830	COG2949	membrane
YEY1_13835	COG0298	carbon dioxide binding
YEY1_13840	COG0375	protein maturation
YEY1_13845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YEY1_13850	COG0651	ATP synthesis coupled electron transport
YEY1_13855	COG0650	Formate hydrogenlyase subunit 4
YEY1_13860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YEY1_13865	COG4237	Hydrogenase 4 membrane
YEY1_13870	COG0651	ATP synthesis coupled electron transport
YEY1_13875	COG3261	NADH dehydrogenase
YEY1_13875	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
YEY1_13880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_13885	COG3260	NADH ubiquinone oxidoreductase 20
YEY1_13895	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YEY1_13900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YEY1_13905	COG3383	formate dehydrogenase (NAD+) activity
YEY1_13910	COG3604	Transcriptional regulator
YEY1_13935	COG2311	Membrane
YEY1_13940	COG0302	gtp cyclohydrolase
YEY1_13945	COG0477	Major facilitator Superfamily
YEY1_13950	COG0583	DNA-binding transcription factor activity
YEY1_13980	COG1136	(ABC) transporter
YEY1_13980	COG0577	efflux transmembrane transporter activity
YEY1_13995	COG0303	'Molybdopterin
YEY1_14000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YEY1_14010	COG0488	(ABC) transporter
YEY1_14030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YEY1_14050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
YEY1_14065	COG4106	trans-aconitate 2-methyltransferase activity
YEY1_14070	COG0783	Belongs to the Dps family
YEY1_14075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YEY1_14080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_14085	COG0765	amino acid transport
YEY1_14090	COG1126	abc transporter atp-binding protein
YEY1_14100	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
YEY1_14125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YEY1_14130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YEY1_14155	COG0697	spore germination
YEY1_14170	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_14180	COG1174	glycine betaine transport
YEY1_14185	COG1125	glycine betaine transport
YEY1_14190	COG1174	glycine betaine transport
YEY1_14195	COG1732	Glycine betaine
YEY1_14210	COG2897	thiosulfate sulfurtransferase activity
YEY1_14215	COG0410	ABC transporter
YEY1_14220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YEY1_14230	COG0559	Belongs to the binding-protein-dependent transport system permease family
YEY1_14240	COG4807	Protein conserved in bacteria
YEY1_14255	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YEY1_14265	COG2261	transglycosylase associated protein
YEY1_14275	COG1403	HNH endonuclease
YEY1_14285	COG0277	FAD linked oxidase domain protein
YEY1_14290	COG1686	Belongs to the peptidase S11 family
YEY1_14300	COG2239	Acts as a magnesium transporter
YEY1_14310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YEY1_14315	COG0513	Belongs to the DEAD box helicase family
YEY1_14320	COG1309	transcriptional regulator
YEY1_14325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_14330	COG1131	(ABC) transporter
YEY1_14335	COG0842	Transport permease protein
YEY1_14340	COG0842	Transport permease protein
YEY1_14345	COG0670	Belongs to the BI1 family
YEY1_14350	COG0314	molybdopterin synthase activity
YEY1_14355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YEY1_14360	COG0315	cyclic pyranopterin monophosphate synthase activity
YEY1_14365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YEY1_14370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YEY1_14375	COG4628	conserved protein (DUF2132)
YEY1_14380	COG0556	nucleotide-excision repair
YEY1_14390	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YEY1_14395	COG2226	methyltransferase
YEY1_14400	COG0156	8-amino-7-oxononanoate synthase activity
YEY1_14405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YEY1_14415	COG2706	6-phosphogluconolactonase activity
YEY1_14425	COG0561	phosphatase activity
YEY1_14435	COG4149	molybdate abc transporter
YEY1_14440	COG0725	ABC transporter, periplasmic molybdate-binding protein
YEY1_14450	COG3585	molybdate ion transport
YEY1_14450	COG2005	Transcriptional regulator
YEY1_14455	COG1119	ATPase activity
YEY1_14465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YEY1_14470	COG1085	galactose-1-phosphate uridylyltransferase
YEY1_14475	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
YEY1_14480	COG2017	converts alpha-aldose to the beta-anomer
YEY1_14505	COG0588	phosphoglycerate mutase activity
YEY1_14510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YEY1_14515	COG1230	cation diffusion facilitator family transporter
YEY1_14525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YEY1_14560	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YEY1_14565	COG2885	chlorophyll binding
YEY1_14570	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_14575	COG3064	Membrane
YEY1_14575	COG3064	Membrane
YEY1_14580	COG0848	biopolymer transport protein
YEY1_14585	COG0811	peptide transport
YEY1_14590	COG0824	Thioesterase
YEY1_14595	COG3790	cyd operon protein YbgE
YEY1_14600	COG4890	Cyd operon protein YbgT
YEY1_14605	COG1294	oxidase, subunit
YEY1_14610	COG1271	oxidase subunit
YEY1_14615	COG0737	Belongs to the 5'-nucleotidase family
YEY1_14620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YEY1_14625	COG0045	succinate-CoA ligase (ADP-forming) activity
YEY1_14630	COG0508	dehydrogenase complex catalyzes the overall conversion of
YEY1_14635	COG0567	Dehydrogenase, E1 component
YEY1_14645	COG1053	succinate dehydrogenase
YEY1_14650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YEY1_14655	COG2009	succinate dehydrogenase
YEY1_14670	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YEY1_14685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YEY1_14690	COG1984	allophanate hydrolase subunit 2
YEY1_14700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YEY1_14705	COG5212	phosphodiesterase
YEY1_14715	COG3272	Protein of unknown function (DUF1722)
YEY1_14720	COG3064	Membrane
YEY1_14720	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YEY1_14720	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YEY1_14720	COG1073	alpha beta
YEY1_14720	COG3064	Membrane
YEY1_14720	COG1073	alpha beta
YEY1_14725	COG2994	toxin metabolic process
YEY1_14750	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YEY1_14755	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YEY1_14760	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YEY1_14765	COG2205	protein histidine kinase activity
YEY1_14770	COG0745	RESPONSE REGULATOR receiver
YEY1_14785	COG0033	Phosphoglucomutase
YEY1_14790	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YEY1_14795	COG0596	Alpha beta hydrolase
YEY1_14805	COG0840	transmembrane signaling receptor activity
YEY1_14815	COG0735	belongs to the Fur family
YEY1_14835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YEY1_14840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_14840	COG1263	PTS System
YEY1_14840	COG2190	(PTS) system
YEY1_14845	COG0363	glucosamine-6-phosphate deaminase activity
YEY1_14850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YEY1_14855	COG1940	carbohydrate kinase activity
YEY1_14855	COG1846	Transcriptional regulator
YEY1_14860	COG0647	UMP catabolic process
YEY1_14865	COG0367	asparagine synthase
YEY1_14900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YEY1_14905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YEY1_14910	COG1702	phosphate starvation-inducible protein PhoH
YEY1_14915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YEY1_14920	COG4535	Mg2 and Co2 transporter CorC
YEY1_14925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YEY1_14940	COG0765	amino acid transport
YEY1_14945	COG0765	amino acid transport
YEY1_14950	COG1126	abc transporter atp-binding protein
YEY1_14955	COG2888	peptidyl-tyrosine sulfation
YEY1_14960	COG0495	leucyl-tRNA aminoacylation
YEY1_14965	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
YEY1_14970	COG1466	dna polymerase III delta subunit
YEY1_14975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YEY1_14980	COG0799	negative regulation of ribosome biogenesis
YEY1_14990	COG0768	penicillin binding
YEY1_14995	COG0772	Belongs to the SEDS family
YEY1_15000	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YEY1_15005	COG1686	Belongs to the peptidase S11 family
YEY1_15010	COG2921	Belongs to the UPF0250 family
YEY1_15015	COG0321	lipoyl(octanoyl) transferase activity
YEY1_15020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YEY1_15025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YEY1_15030	COG3706	GGDEF domain
YEY1_15035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YEY1_15040	COG1278	Cold shock
YEY1_15045	COG1278	Cold shock
YEY1_15050	COG2197	response regulator
YEY1_15060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YEY1_15075	COG5265	(ABC) transporter
YEY1_15085	COG2986	histidine ammonia-lyase
YEY1_15090	COG2850	peptidyl-arginine hydroxylation
YEY1_15105	COG0582	viral genome integration into host DNA
YEY1_15180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YEY1_15185	COG2501	S4 domain
YEY1_15190	COG0215	cysteine-tRNA ligase activity
YEY1_15195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YEY1_15200	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YEY1_15205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YEY1_15210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YEY1_15215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YEY1_15220	COG4181	ATPase activity
YEY1_15225	COG2755	lipolytic protein G-D-S-L family
YEY1_15230	COG0300	oxidoreductase activity
YEY1_15235	COG3118	belongs to the thioredoxin family
YEY1_15240	COG0330	HflC and HflK could
YEY1_15245	COG1585	Membrane protein implicated in regulation of membrane protease activity
YEY1_15250	COG0789	Transcriptional regulator
YEY1_15255	COG2217	Heavy metal translocating P-type atpase
YEY1_15260	COG3735	TraB family
YEY1_15265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YEY1_15275	COG0737	Belongs to the 5'-nucleotidase family
YEY1_15280	COG2223	nitrite transmembrane transporter activity
YEY1_15285	COG4651	solute:proton antiporter activity
YEY1_15285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YEY1_15290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_15310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YEY1_15320	COG0438	transferase activity, transferring glycosyl groups
YEY1_15325	COG1215	transferase activity, transferring glycosyl groups
YEY1_15330	COG1442	glycosyl transferase family 8
YEY1_15330	COG1216	Glycosyl transferase, family 2
YEY1_15335	COG2244	polysaccharide biosynthetic process
YEY1_15340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YEY1_15345	COG0563	adenylate kinase activity
YEY1_15350	COG0326	Molecular chaperone. Has ATPase activity
YEY1_15355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YEY1_15360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YEY1_15370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YEY1_15375	COG2832	Protein of unknown function (DUF454)
YEY1_15390	COG3264	Mechanosensitive ion channel
YEY1_15390	COG1196	nuclear chromosome segregation
YEY1_15395	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YEY1_15400	COG1309	transcriptional regulator
YEY1_15405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_15410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_15430	COG3457	Alanine racemase
YEY1_15435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YEY1_15450	COG0254	rRNA binding
YEY1_15455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YEY1_15460	COG0803	Belongs to the bacterial solute-binding protein 9 family
YEY1_15465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_15500	COG3695	enzyme binding
YEY1_15505	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YEY1_15510	COG1946	Acyl-CoA thioesterase
YEY1_15515	COG0004	ammonium transporteR
YEY1_15520	COG0347	Belongs to the P(II) protein family
YEY1_15525	COG1132	(ABC) transporter
YEY1_15530	COG1132	(ABC) transporter
YEY1_15535	COG1522	sequence-specific DNA binding
YEY1_15545	COG0561	phosphatase activity
YEY1_15550	COG4533	DNA binding
YEY1_15555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YEY1_15560	COG0824	Thioesterase
YEY1_15565	COG1555	photosystem II stabilization
YEY1_15570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YEY1_15575	COG0776	regulation of translation
YEY1_15580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YEY1_15585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YEY1_15590	COG0740	serine-type endopeptidase activity
YEY1_15595	COG0544	peptidyl-prolyl cis-trans isomerase activity
YEY1_15605	COG0271	Belongs to the BolA IbaG family
YEY1_15610	COG3056	Lipoprotein
YEY1_15615	COG2223	nitrite transmembrane transporter activity
YEY1_15625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YEY1_15630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YEY1_15635	COG1845	cytochrome c oxidase, subunit III
YEY1_15640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YEY1_15645	COG0109	protoheme IX farnesyltransferase activity
YEY1_15650	COG2814	Major facilitator Superfamily
YEY1_15655	COG1666	GTP binding
YEY1_15660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YEY1_15665	COG0693	protein deglycase activity
YEY1_15675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YEY1_15675	COG0301	tRNA thio-modification
YEY1_15685	COG0142	geranyltranstransferase activity
YEY1_15690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YEY1_15700	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YEY1_15705	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YEY1_15710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YEY1_15715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YEY1_15720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YEY1_15720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YEY1_15725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YEY1_15750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YEY1_15755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YEY1_15760	COG1862	Preprotein translocase
YEY1_15765	COG0343	queuine tRNA-ribosyltransferase activity
YEY1_15780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YEY1_15785	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YEY1_15790	COG0450	alkyl hydroperoxide reductase
YEY1_15810	COG0366	Alpha amylase catalytic
YEY1_15820	COG1114	Component of the transport system for branched-chain amino acids
YEY1_15830	COG5002	protein histidine kinase activity
YEY1_15835	COG0745	RESPONSE REGULATOR receiver
YEY1_15840	COG0420	3'-5' exonuclease activity
YEY1_15845	COG0419	ATPase involved in DNA repair
YEY1_15850	COG1940	carbohydrate kinase activity
YEY1_15855	COG2974	May be involved in recombination
YEY1_15860	COG3123	guanosine phosphorylase activity
YEY1_15865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YEY1_15890	COG2226	methyltransferase
YEY1_15905	COG3459	Glycosyltransferase 36 associated
YEY1_15925	COG2188	Transcriptional regulator
YEY1_15930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YEY1_15935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YEY1_15950	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
YEY1_15955	COG2195	Cleaves the N-terminal amino acid of tripeptides
YEY1_15960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YEY1_15975	COG2964	Protein conserved in bacteria
YEY1_15980	COG1181	Belongs to the D-alanine--D-alanine ligase family
YEY1_15995	COG2991	Protein conserved in bacteria
YEY1_16000	COG1477	protein flavinylation
YEY1_16005	COG2871	sodium ion transport
YEY1_16010	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_16015	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_16020	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_16025	COG1805	sodium ion transport
YEY1_16030	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_16035	COG3034	peptidoglycan biosynthetic process
YEY1_16040	COG0121	glutamine amidotransferase
YEY1_16050	COG1960	acyl-CoA dehydrogenase activity
YEY1_16055	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YEY1_16075	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
YEY1_16080	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YEY1_16085	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
YEY1_16090	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
YEY1_16095	COG0235	Class ii aldolase
YEY1_16100	COG0436	Aminotransferase
YEY1_16115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YEY1_16125	COG0765	amino acid transport
YEY1_16130	COG0765	amino acid transport
YEY1_16170	COG2814	Major facilitator Superfamily
YEY1_16180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YEY1_16190	COG1846	Transcriptional regulator
YEY1_16195	COG1538	Outer membrane efflux protein
YEY1_16200	COG1566	PFAM secretion protein HlyD family protein
YEY1_16205	COG2814	Major facilitator Superfamily
YEY1_16220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YEY1_16225	COG3118	belongs to the thioredoxin family
YEY1_16235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YEY1_16235	COG1042	CoA-binding domain protein
YEY1_16235	COG0045	succinate-CoA ligase (ADP-forming) activity
YEY1_16240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YEY1_16245	COG5544	Lipoprotein
YEY1_16275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YEY1_16280	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YEY1_16290	COG0564	pseudouridine synthase activity
YEY1_16300	COG0542	response to heat
YEY1_16310	COG1605	Chorismate mutase
YEY1_16310	COG0077	Prephenate dehydratase
YEY1_16320	COG1605	Chorismate mutase
YEY1_16320	COG0287	Prephenate dehydrogenase
YEY1_16325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YEY1_16330	COG3279	Response regulator of the LytR AlgR family
YEY1_16335	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YEY1_16340	COG3137	Salt-induced outer membrane protein
YEY1_16345	COG0335	large ribosomal subunit rRNA binding
YEY1_16350	COG0336	Belongs to the RNA methyltransferase TrmD family
YEY1_16355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YEY1_16360	COG0228	four-way junction DNA binding
YEY1_16365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YEY1_16370	COG4137	Cytochrome C assembly protein
YEY1_16375	COG4536	flavin adenine dinucleotide binding
YEY1_16380	COG1854	S-ribosylhomocysteine lyase activity
YEY1_16385	COG2918	glutathione biosynthetic process
YEY1_16390	COG1238	metal cluster binding
YEY1_16395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_16415	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YEY1_16420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YEY1_16425	COG2137	regulation of response to DNA damage stimulus
YEY1_16430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YEY1_16450	COG3381	protein complex oligomerization
YEY1_16455	COG3302	dmso reductase anchor subunit
YEY1_16460	COG0437	4 iron, 4 sulfur cluster binding
YEY1_16465	COG0243	molybdopterin cofactor binding
YEY1_16470	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_16470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_16480	COG0559	Belongs to the binding-protein-dependent transport system permease family
YEY1_16485	COG4177	L-phenylalanine transmembrane transporter activity
YEY1_16490	COG1137	ATPase activity
YEY1_16495	COG0410	ABC transporter
YEY1_16550	COG0640	Transcriptional regulator
YEY1_16555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YEY1_16570	COG1858	cytochrome C peroxidase
YEY1_16575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YEY1_16585	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_16605	COG1538	Outer membrane efflux protein
YEY1_16615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_16645	COG3539	Fimbrial protein
YEY1_16650	COG3539	Fimbrial protein
YEY1_16660	COG3121	Chaperone
YEY1_16665	COG3188	usher protein
YEY1_16690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YEY1_16695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YEY1_16700	COG1388	LysM domain
YEY1_16700	COG4942	peptidase
YEY1_16710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YEY1_16715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YEY1_16720	COG0585	pseudouridine synthase activity
YEY1_16725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YEY1_16735	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
YEY1_16745	COG0529	Catalyzes the synthesis of activated sulfate
YEY1_16750	COG2895	sulfate adenylyltransferase (ATP) activity
YEY1_16755	COG0175	sulfate reduction
YEY1_16760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YEY1_16760	COG1648	precorrin-2 dehydrogenase activity
YEY1_16765	COG2234	aminopeptidase activity
YEY1_16785	COG0175	sulfate reduction
YEY1_16790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YEY1_16795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YEY1_16800	COG0720	synthase
YEY1_16820	COG0602	queuosine metabolic process
YEY1_16855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YEY1_16860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YEY1_16865	COG0583	DNA-binding transcription factor activity
YEY1_16875	COG1279	arginine transmembrane transporter activity
YEY1_16895	COG0191	fructose-bisphosphate aldolase activity
YEY1_16900	COG0126	phosphoglycerate kinase activity
YEY1_16905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YEY1_16910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YEY1_16915	COG0501	Belongs to the peptidase M48B family
YEY1_16925	COG1166	arginine decarboxylase activity
YEY1_16930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YEY1_16945	COG0640	Transcriptional regulator
YEY1_16950	COG3091	SprT-like family
YEY1_16955	COG2356	endonuclease I
YEY1_16960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YEY1_16965	COG0189	ligase activity
YEY1_16970	COG1678	Uncharacterized ACR, COG1678
YEY1_16975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YEY1_16980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YEY1_16990	COG2805	Type II/IV secretion system protein
YEY1_16995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YEY1_17000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YEY1_17005	COG0762	integral membrane protein
YEY1_17010	COG1872	DUF167
YEY1_17015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YEY1_17020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YEY1_17030	COG2066	Belongs to the glutaminase family
YEY1_17035	COG3171	Protein conserved in bacteria
YEY1_17040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YEY1_17045	COG1194	a g-specific adenine glycosylase
YEY1_17050	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YEY1_17055	COG0741	lytic transglycosylase activity
YEY1_17065	COG1982	Orn Lys Arg decarboxylase major
YEY1_17080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YEY1_17125	COG0531	amino acid
YEY1_17130	COG1982	Orn Lys Arg decarboxylase major
YEY1_17145	COG1289	transmembrane transporter activity
YEY1_17170	COG0024	Methionine aminopeptidase
YEY1_17175	COG4604	ABC transporter, ATP-binding protein
YEY1_17180	COG4605	iron ion homeostasis
YEY1_17190	COG4607	ABC-type enterochelin transport system periplasmic component
YEY1_17205	COG0697	spore germination
YEY1_17210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_17225	COG0477	Major facilitator Superfamily
YEY1_17230	COG1609	Transcriptional regulator
YEY1_17240	COG1283	sodium-dependent phosphate transmembrane transporter activity
YEY1_17255	COG0477	Major facilitator Superfamily
YEY1_17275	COG5001	Diguanylate cyclase
YEY1_17290	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
YEY1_17300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
YEY1_17305	COG0309	Hydrogenase expression formation protein (HypE)
YEY1_17310	COG0409	Hydrogenase expression formation protein
YEY1_17315	COG0298	carbon dioxide binding
YEY1_17320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YEY1_17325	COG0375	protein maturation
YEY1_17330	COG1773	rubredoxin
YEY1_17335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YEY1_17340	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
YEY1_17345	COG5557	Pfam Polysulphide reductase, NrfD
YEY1_17350	COG0437	4 iron, 4 sulfur cluster binding
YEY1_17355	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
YEY1_17365	COG3133	Outer membrane lipoprotein
YEY1_17375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YEY1_17380	COG1191	sigma factor activity
YEY1_17400	COG1516	flagellar protein fliS
YEY1_17405	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YEY1_17410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YEY1_17420	COG3710	Transcriptional regulator
YEY1_17450	COG1706	bacterial-type flagellum-dependent cell motility
YEY1_17460	COG4786	Flagellar basal body rod
YEY1_17470	COG1749	Flagellar hook protein flgE
YEY1_17475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YEY1_17480	COG1558	bacterial-type flagellum-dependent cell motility
YEY1_17485	COG1815	bacterial-type flagellum-dependent cell motility
YEY1_17525	COG0577	efflux transmembrane transporter activity
YEY1_17525	COG1136	(ABC) transporter
YEY1_17605	COG4964	Belongs to the GSP D family
YEY1_17655	COG0848	biopolymer transport protein
YEY1_17660	COG0811	peptide transport
YEY1_17665	COG0626	cystathionine gamma-synthase activity
YEY1_17670	COG0586	Pfam SNARE associated Golgi protein
YEY1_17675	COG2207	Transcriptional regulator
YEY1_17680	COG1979	alcohol dehydrogenase
YEY1_17685	COG0656	L-ascorbic acid biosynthetic process
YEY1_17695	COG2132	Multicopper oxidase
YEY1_17705	COG0204	Acyl-transferase
YEY1_17710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YEY1_17720	COG2249	NAD(P)H dehydrogenase (quinone) activity
YEY1_17725	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YEY1_17735	COG0187	DNA topoisomerase II activity
YEY1_17740	COG3150	esterase
YEY1_17745	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YEY1_17750	COG3151	Protein conserved in bacteria
YEY1_17755	COG0494	nUDIX hydrolase
YEY1_17760	COG1538	Outer membrane efflux protein
YEY1_17765	COG5463	Belongs to the UPF0441 family
YEY1_17770	COG0754	glutathionylspermidine amidase activity
YEY1_17775	COG3384	dioxygenase
YEY1_17785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YEY1_17795	COG0531	amino acid
YEY1_17800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YEY1_17800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YEY1_17805	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YEY1_17810	COG3025	triphosphatase activity
YEY1_17815	COG4991	sh3 domain protein
YEY1_17820	COG0617	tRNA 3'-terminal CCA addition
YEY1_17825	COG1968	undecaprenyl-diphosphatase activity
YEY1_17830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YEY1_17835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
YEY1_17840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YEY1_17850	COG0358	DNA primase activity
YEY1_17855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YEY1_17945	COG2856	Zn peptidase
YEY1_18025	COG4695	Portal protein
YEY1_18090	COG4974	Belongs to the 'phage' integrase family
YEY1_18095	COG3876	Protein conserved in bacteria
YEY1_18105	COG1472	Belongs to the glycosyl hydrolase 3 family
YEY1_18115	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
YEY1_18120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_18120	COG1263	PTS System
YEY1_18130	COG0531	amino acid
YEY1_18135	COG0076	glutamate decarboxylase activity
YEY1_18150	COG3247	response to pH
YEY1_18160	COG0446	pyridine nucleotide-disulphide oxidoreductase
YEY1_18160	COG1902	pentaerythritol trinitrate reductase activity
YEY1_18170	COG2813	Specifically methylates the guanine in position
YEY1_18190	COG1451	nucleotide metabolic process
YEY1_18195	COG0673	inositol 2-dehydrogenase activity
YEY1_18205	COG0861	Integral membrane protein TerC family
YEY1_18210	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
YEY1_18220	COG2721	sulfolactate sulfo-lyase activity
YEY1_18225	COG0246	Mannitol dehydrogenase
YEY1_18230	COG1904	glucuronate isomerase
YEY1_18235	COG2271	Major facilitator Superfamily
YEY1_18250	COG0586	Pfam SNARE associated Golgi protein
YEY1_18265	COG4575	ribosome binding
YEY1_18270	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YEY1_18280	COG2259	Doxx family
YEY1_18285	COG0435	Glutathione S-transferase
YEY1_18290	COG0583	DNA-binding transcription factor activity
YEY1_18295	COG1741	Belongs to the pirin family
YEY1_18305	COG0667	Aldo Keto reductase
YEY1_18325	COG3121	Chaperone
YEY1_18380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YEY1_18390	COG0792	nuclease activity
YEY1_18395	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YEY1_18400	COG2823	Periplasmic or secreted lipoprotein
YEY1_18415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YEY1_18420	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YEY1_18430	COG2198	Histidine kinase
YEY1_18430	COG0784	Response regulator, receiver
YEY1_18430	COG5002	protein histidine kinase activity
YEY1_18440	COG0067	glutamate synthase
YEY1_18440	COG0069	glutamate synthase activity
YEY1_18440	COG0070	glutamate synthase
YEY1_18445	COG0493	'glutamate synthase
YEY1_18460	COG2969	positive regulation of protein catabolic process
YEY1_18465	COG0625	glutathione transferase activity
YEY1_18470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YEY1_18475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YEY1_18480	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YEY1_18485	COG3105	Protein conserved in bacteria
YEY1_18495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YEY1_18500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YEY1_18505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YEY1_18510	COG5007	Belongs to the BolA IbaG family
YEY1_18515	COG3113	response to antibiotic
YEY1_18520	COG2854	intermembrane phospholipid transfer
YEY1_18525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YEY1_18530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YEY1_18535	COG1127	ABC transporter
YEY1_18545	COG0530	calcium, potassium:sodium antiporter activity
YEY1_18550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YEY1_18550	COG0517	IMP dehydrogenase activity
YEY1_18555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YEY1_18560	COG3117	lipopolysaccharide transmembrane transporter activity
YEY1_18565	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YEY1_18570	COG1137	ATPase activity
YEY1_18575	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YEY1_18585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_18590	COG1660	Displays ATPase and GTPase activities
YEY1_18595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_18610	COG0540	Belongs to the ATCase OTCase family
YEY1_18615	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
YEY1_18625	COG2308	Evidence 4 Homologs of previously reported genes of
YEY1_18645	COG0366	Alpha amylase catalytic
YEY1_18650	COG1263	PTS System
YEY1_18650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_18665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YEY1_18675	COG3093	addiction module antidote protein HigA
YEY1_18680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_18680	COG3711	transcriptional antiterminator
YEY1_18685	COG2706	6-phosphogluconolactonase activity
YEY1_18700	COG3964	amidohydrolase
YEY1_18730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YEY1_18735	COG3783	Cytochrome b(562)
YEY1_18745	COG0312	modulator of DNA gyrase
YEY1_18750	COG3028	Belongs to the UPF0307 family
YEY1_18755	COG2732	(Barnase) inhibitor
YEY1_18770	COG1289	transmembrane transporter activity
YEY1_18775	COG1566	PFAM secretion protein HlyD family protein
YEY1_18785	COG0583	DNA-binding transcription factor activity
YEY1_18845	COG0312	modulator of DNA gyrase
YEY1_18850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YEY1_18855	COG3164	Protein of unknown function
YEY1_18860	COG1530	ribonuclease E activity
YEY1_18870	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YEY1_18875	COG1792	Involved in formation and maintenance of cell shape
YEY1_18880	COG1077	Cell shape determining protein MreB Mrl
YEY1_18885	COG2199	diguanylate cyclase activity
YEY1_18885	COG2200	EAL domain
YEY1_18890	COG0604	alcohol dehydrogenase
YEY1_18900	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
YEY1_18905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YEY1_18910	COG0511	ligase activity, forming carbon-carbon bonds
YEY1_18915	COG0439	Biotin carboxylase
YEY1_18920	COG3924	membrane
YEY1_18925	COG4145	pantothenate transmembrane transporter activity
YEY1_18930	COG2264	protein methyltransferase activity
YEY1_18940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YEY1_18945	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YEY1_18950	COG0745	RESPONSE REGULATOR receiver
YEY1_18950	COG3706	GGDEF domain
YEY1_18955	COG3133	Outer membrane lipoprotein
YEY1_18960	COG1278	Cold shock
YEY1_18965	COG1278	Cold shock
YEY1_18975	COG0471	metal ion transport
YEY1_18980	COG1560	Kdo2-lipid A biosynthetic process
YEY1_19000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_19005	COG4597	amino acid ABC transporter
YEY1_19010	COG0765	amino acid transport
YEY1_19015	COG1126	abc transporter atp-binding protein
YEY1_19025	COG1380	Effector of murein hydrolase LrgA
YEY1_19030	COG0583	DNA-binding transcription factor activity
YEY1_19035	COG0025	NhaP-type Na H and K H
YEY1_19040	COG2252	PERMEase
YEY1_19055	COG3550	peptidyl-serine autophosphorylation
YEY1_19065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YEY1_19070	COG2315	Protein conserved in bacteria
YEY1_19075	COG1448	Aminotransferase
YEY1_19080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YEY1_19085	COG0305	Participates in initiation and elongation during chromosome replication
YEY1_19105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YEY1_19115	COG0735	belongs to the Fur family
YEY1_19120	COG3237	CsbD-like
YEY1_19125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YEY1_19130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YEY1_19135	COG2937	Belongs to the GPAT DAPAT family
YEY1_19140	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YEY1_19145	COG3161	chorismate lyase activity
YEY1_19160	COG4580	involved in the transport of maltose and maltodextrins
YEY1_19175	COG2182	Extracellular solute-binding protein
YEY1_19180	COG1175	transmembrane transport
YEY1_19185	COG3833	ABC-type maltose transport systems, permease component
YEY1_19195	COG0166	Belongs to the GPI family
YEY1_19200	COG0527	aspartate kinase activity
YEY1_19225	COG1414	Transcriptional regulator
YEY1_19230	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
YEY1_19235	COG2224	Isocitrate lyase
YEY1_19240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YEY1_19245	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
YEY1_19295	COG0138	bifunctional purine biosynthesis protein purh
YEY1_19300	COG0151	Belongs to the GarS family
YEY1_19315	COG3068	Protein conserved in bacteria
YEY1_19320	COG1515	deoxyribonuclease V activity
YEY1_19325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YEY1_19330	COG2816	NAD+ diphosphatase activity
YEY1_19335	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
YEY1_19340	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YEY1_19350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YEY1_19355	COG2104	thiamine diphosphate biosynthetic process
YEY1_19360	COG2022	thiamine diphosphate biosynthetic process
YEY1_19375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YEY1_19380	COG0085	RNA polymerase activity
YEY1_19385	COG0222	ribosome binding
YEY1_19390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YEY1_19395	COG0081	regulation of translation
YEY1_19400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YEY1_19405	COG0250	Participates in transcription elongation, termination and antitermination
YEY1_19410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YEY1_19415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YEY1_19450	COG1072	(Pantothenic acid kinase))
YEY1_19455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
YEY1_19455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
YEY1_19505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YEY1_19510	COG1739	Uncharacterized protein family UPF0029
YEY1_19515	COG0006	proline dipeptidase activity
YEY1_19520	COG1024	Enoyl-CoA hydratase
YEY1_19520	COG1250	3-hydroxyacyl-CoA dehydrogenase
YEY1_19525	COG0183	Belongs to the thiolase family
YEY1_19535	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YEY1_19555	COG0805	protein transport
YEY1_19560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YEY1_19565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YEY1_19570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YEY1_19580	COG2226	methyltransferase
YEY1_19585	COG1322	Protein conserved in bacteria
YEY1_19590	COG0586	Pfam SNARE associated Golgi protein
YEY1_19595	COG1966	Carbon starvation protein
YEY1_19610	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YEY1_19615	COG0412	Dienelactone hydrolase
YEY1_19620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YEY1_19625	COG0583	DNA-binding transcription factor activity
YEY1_19635	COG0679	Auxin Efflux Carrier
YEY1_19640	COG0584	glycerophosphoryl diester phosphodiesterase
YEY1_19645	COG3842	ATPase activity
YEY1_19650	COG0395	ABC-type sugar transport system, permease component
YEY1_19655	COG1175	transmembrane transport
YEY1_19695	COG0410	ABC transporter
YEY1_19700	COG0411	ABC transporter
YEY1_19705	COG4177	L-phenylalanine transmembrane transporter activity
YEY1_19710	COG0559	Belongs to the binding-protein-dependent transport system permease family
YEY1_19715	COG0683	leucine binding
YEY1_19745	COG2177	Part of the ABC transporter FtsEX involved in
YEY1_19750	COG2884	Cell division ATP-binding protein ftsE
YEY1_19755	COG0552	protein localization to endoplasmic reticulum
YEY1_19760	COG0742	ribosomal rna small subunit methyltransferase
YEY1_19765	COG3776	membrane
YEY1_19780	COG3714	YhhN family
YEY1_19785	COG2217	Heavy metal translocating P-type atpase
YEY1_19790	COG0425	Belongs to the sulfur carrier protein TusA family
YEY1_19795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YEY1_19805	COG0247	lactate metabolic process
YEY1_19810	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
YEY1_19815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YEY1_19820	COG2271	Major facilitator Superfamily
YEY1_19825	COG0584	glycerophosphoryl diester phosphodiesterase
YEY1_19835	COG0561	phosphatase activity
YEY1_19840	COG2267	carboxylic ester hydrolase activity
YEY1_19845	COG1280	lysine exporter protein (LysE YggA)
YEY1_19850	COG1280	lysine exporter protein (LysE YggA)
YEY1_19855	COG0514	ATP-dependent DNA helicase (RecQ)
YEY1_19860	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YEY1_19865	COG2050	protein possibly involved in aromatic compounds catabolism
YEY1_19875	COG0598	Magnesium transport protein CorA
YEY1_19880	COG5564	TIM-barrel signal transduction protein
YEY1_19885	COG5441	Belongs to the UPF0261 family
YEY1_19895	COG0210	DNA helicase
YEY1_19900	COG1011	Hydrolase
YEY1_19905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YEY1_19910	COG3159	Protein conserved in bacteria
YEY1_19915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YEY1_19920	COG5567	small periplasmic lipoprotein
YEY1_19925	COG1965	Belongs to the frataxin family
YEY1_19930	COG3072	Adenylate cyclase
YEY1_19935	COG0181	hydroxymethylbilane synthase activity
YEY1_19940	COG1587	Uroporphyrinogen-III synthase
YEY1_19945	COG2959	enzyme of heme biosynthesis
YEY1_19950	COG3071	HemY protein
YEY1_19985	COG1113	amino acid transport
YEY1_20000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YEY1_20005	COG2244	polysaccharide biosynthetic process
YEY1_20010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YEY1_20015	COG0456	acetyltransferase
YEY1_20020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YEY1_20030	COG1088	dTDP-glucose 4,6-dehydratase activity
YEY1_20035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YEY1_20040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YEY1_20045	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YEY1_20050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YEY1_20055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YEY1_20060	COG3118	belongs to the thioredoxin family
YEY1_20070	COG0248	Ppx GppA phosphatase
YEY1_20085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YEY1_20095	COG3121	Chaperone
YEY1_20110	COG3121	Chaperone
YEY1_20135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YEY1_20140	COG0583	DNA-binding transcription factor activity
YEY1_20165	COG0129	dihydroxy-acid dehydratase activity
YEY1_20170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YEY1_20175	COG3978	acetolactate synthase activity
YEY1_20195	COG3085	chromosome segregation
YEY1_20200	COG0583	DNA-binding transcription factor activity
YEY1_20205	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_20210	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_20215	COG1129	ABC transporter
YEY1_20220	COG1879	ABC-type sugar transport system periplasmic component
YEY1_20265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YEY1_20275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YEY1_20285	COG1309	transcriptional regulator
YEY1_20290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_20300	COG0678	peroxiredoxin activity
YEY1_20300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YEY1_20310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_20350	COG1629	transport
YEY1_20355	COG0165	Argininosuccinate lyase
YEY1_20360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YEY1_20365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YEY1_20375	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YEY1_20385	COG0460	homoserine dehydrogenase
YEY1_20385	COG0527	aspartate kinase activity
YEY1_20390	COG0626	cystathionine gamma-synthase activity
YEY1_20395	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YEY1_20400	COG0254	rRNA binding
YEY1_20405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YEY1_20410	COG1609	Transcriptional regulator
YEY1_20415	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YEY1_20420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YEY1_20425	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YEY1_20430	COG1575	Belongs to the MenA family. Type 1 subfamily
YEY1_20435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YEY1_20440	COG3074	FtsZ-dependent cytokinesis
YEY1_20450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YEY1_20460	COG1494	fructose-1,6-bisphosphatase
YEY1_20470	COG2814	Major facilitator Superfamily
YEY1_20490	COG3152	Membrane
YEY1_20500	COG0149	triose-phosphate isomerase activity
YEY1_20510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YEY1_20520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
YEY1_20605	COG4695	Portal protein
YEY1_20620	COG0653	protein targeting
YEY1_20645	COG4974	Belongs to the 'phage' integrase family
YEY1_20650	COG3678	ATP-independent chaperone mediated protein folding
YEY1_20655	COG0745	RESPONSE REGULATOR receiver
YEY1_20660	COG2205	protein histidine kinase activity
YEY1_20665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YEY1_20665	COG2169	Transcriptional regulator
YEY1_20670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YEY1_20675	COG1045	serine acetyltransferase
YEY1_20680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YEY1_20685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YEY1_20690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YEY1_20695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YEY1_20700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YEY1_20705	COG4942	peptidase
YEY1_20710	COG2861	carbohydrate metabolic process
YEY1_20725	COG1063	alcohol dehydrogenase
YEY1_20730	COG0156	8-amino-7-oxononanoate synthase activity
YEY1_20735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_20740	COG0859	PFAM glycosyl transferase family 9
YEY1_20745	COG0859	PFAM glycosyl transferase family 9
YEY1_20750	COG1519	Transferase
YEY1_20760	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YEY1_20765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YEY1_20770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YEY1_20775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YEY1_20785	COG2003	Belongs to the UPF0758 family
YEY1_20790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YEY1_20795	COG0756	dUTP diphosphatase activity
YEY1_20800	COG1309	transcriptional regulator
YEY1_20810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YEY1_20815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YEY1_20820	COG1561	YicC-like family, N-terminal region
YEY1_20835	COG5001	Diguanylate cyclase
YEY1_20840	COG1024	Enoyl-CoA hydratase
YEY1_20845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YEY1_20855	COG2860	membrane
YEY1_20860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YEY1_20870	COG1758	RNA polymerase activity
YEY1_20875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YEY1_20880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YEY1_20885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YEY1_20900	COG0786	glutamate:sodium symporter activity
YEY1_20905	COG2233	PERMEase
YEY1_20910	COG2982	Protein involved in outer membrane biogenesis
YEY1_20930	COG3423	Transcriptional regulator
YEY1_20935	COG0456	acetyltransferase
YEY1_20945	COG1490	D-aminoacyl-tRNA deacylase activity
YEY1_20950	COG1295	ribonuclease BN
YEY1_20955	COG1011	Hydrolase
YEY1_20970	COG0174	glutamine synthetase
YEY1_20980	COG3852	Histidine kinase
YEY1_20995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YEY1_21005	COG3078	GTPase activator activity
YEY1_21010	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YEY1_21015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YEY1_21015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YEY1_21020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YEY1_21025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YEY1_21030	COG3084	Protein conserved in bacteria
YEY1_21040	COG1763	Mo-molybdopterin cofactor biosynthetic process
YEY1_21075	COG2186	Transcriptional regulator
YEY1_21080	COG0477	Major facilitator Superfamily
YEY1_21085	COG1609	Transcriptional regulator
YEY1_21090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_21095	COG1879	ABC-type sugar transport system periplasmic component
YEY1_21100	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_21110	COG1869	D-ribose catabolic process
YEY1_21115	COG3158	transport of potassium into the cell
YEY1_21120	COG0714	Associated with various cellular activities
YEY1_21125	COG2425	protein containing a von Willebrand factor type A (vWA) domain
YEY1_21135	COG2502	aspartate--ammonia ligase
YEY1_21140	COG1522	sequence-specific DNA binding
YEY1_21145	COG0716	FMN binding
YEY1_21150	COG0445	tRNA wobble uridine modification
YEY1_21155	COG0357	Ribosomal RNA small subunit methyltransferase G
YEY1_21160	COG3312	ion transport
YEY1_21165	COG0356	it plays a direct role in the translocation of protons across the membrane
YEY1_21175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YEY1_21180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YEY1_21185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YEY1_21190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YEY1_21195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YEY1_21200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YEY1_21205	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YEY1_21210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YEY1_21215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YEY1_21220	COG0573	inorganic phosphate transmembrane transporter activity
YEY1_21225	COG0581	inorganic phosphate transmembrane transporter activity
YEY1_21235	COG0704	Plays a role in the regulation of phosphate uptake
YEY1_21245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_21250	COG0765	amino acid transport
YEY1_21255	COG0765	amino acid transport
YEY1_21260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_21265	COG2252	PERMEase
YEY1_21275	COG4566	intracellular signal transduction
YEY1_21285	COG0431	NADPH-dependent FMN reductase
YEY1_21290	COG0840	transmembrane signaling receptor activity
YEY1_21295	COG2011	ABC-type metal ion transport system permease component
YEY1_21310	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YEY1_21315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YEY1_21320	COG0706	membrane insertase activity
YEY1_21330	COG0594	ribonuclease P activity
YEY1_21335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YEY1_21350	COG1192	Involved in chromosome partitioning
YEY1_21365	COG3609	addiction module antidote protein, CC2985 family
YEY1_21480	COG4792	protein secretion
YEY1_21485	COG4791	protein targeting
YEY1_21490	COG4794	Type iii secretion
YEY1_21495	COG4790	Type iii secretion
YEY1_21500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YEY1_21585	COG4886	Leucine-rich repeat (LRR) protein
YEY1_21585	COG4886	Leucine-rich repeat (LRR) protein
YEY1_21785	COG0640	Transcriptional regulator
YEY1_21790	COG0431	NADPH-dependent FMN reductase