locus-tag	class	description
CRN74_00005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRN74_00015	COG0772	Belongs to the SEDS family
CRN74_00020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CRN74_00025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CRN74_00035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CRN74_00040	COG0849	cell division
CRN74_00045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CRN74_00065	COG0653	protein targeting
CRN74_00070	COG0494	nUDIX hydrolase
CRN74_00075	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CRN74_00085	COG0237	dephospho-CoA kinase activity
CRN74_00095	COG0516	GMP reductase activity
CRN74_00100	COG1459	type II secretion system
CRN74_00105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CRN74_00110	COG4969	Belongs to the N-Me-Phe pilin family
CRN74_00120	COG3023	N-Acetylmuramoyl-L-alanine amidase
CRN74_00125	COG3725	Membrane protein required for beta-lactamase induction
CRN74_00135	COG1113	amino acid transport
CRN74_00140	COG2186	Transcriptional regulator
CRN74_00145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CRN74_00150	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRN74_00155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN74_00175	COG3112	Uncharacterised protein family (UPF0231)
CRN74_00190	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CRN74_00200	COG2132	Multicopper oxidase
CRN74_00210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CRN74_00215	COG0288	reversible hydration of carbon dioxide
CRN74_00220	COG1131	(ABC) transporter
CRN74_00225	COG0842	Transport permease protein
CRN74_00230	COG0726	polysaccharide deacetylase
CRN74_00235	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CRN74_00240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CRN74_00245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CRN74_00250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CRN74_00255	COG0617	tRNA 3'-terminal CCA addition
CRN74_00265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CRN74_00280	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CRN74_00285	COG1643	Atp-dependent helicase
CRN74_00290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRN74_00295	COG1120	ATPase activity
CRN74_00300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRN74_00305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN74_00310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CRN74_00320	COG0316	Belongs to the HesB IscA family
CRN74_00335	COG2860	membrane
CRN74_00345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CRN74_00350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CRN74_00355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRN74_00365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CRN74_00370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CRN74_00375	COG3956	TIGRFAM MazG family protein
CRN74_00380	COG0504	CTP synthase activity
CRN74_00395	COG0602	queuosine metabolic process
CRN74_00400	COG0720	synthase
CRN74_00405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CRN74_00410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRN74_00415	COG0175	sulfate reduction
CRN74_00420	COG2234	aminopeptidase activity
CRN74_00425	COG1648	precorrin-2 dehydrogenase activity
CRN74_00425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CRN74_00430	COG0175	sulfate reduction
CRN74_00435	COG2895	sulfate adenylyltransferase (ATP) activity
CRN74_00440	COG0529	Catalyzes the synthesis of activated sulfate
CRN74_00455	COG0765	amino acid transport
CRN74_00470	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CRN74_00480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CRN74_00485	COG0585	pseudouridine synthase activity
CRN74_00490	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CRN74_00500	COG1388	LysM domain
CRN74_00500	COG4942	peptidase
CRN74_00505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CRN74_00510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CRN74_00515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CRN74_00530	COG0626	cystathionine gamma-synthase activity
CRN74_00545	COG3121	Chaperone
CRN74_00555	COG3121	Chaperone
CRN74_00560	COG3121	Chaperone
CRN74_00575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_00575	COG1263	PTS System
CRN74_00580	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CRN74_00590	COG1472	Belongs to the glycosyl hydrolase 3 family
CRN74_00600	COG3876	Protein conserved in bacteria
CRN74_00625	COG3188	usher protein
CRN74_00630	COG3121	Chaperone
CRN74_00645	COG3539	Fimbrial protein
CRN74_00650	COG3539	Fimbrial protein
CRN74_00680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_00685	COG0577	efflux transmembrane transporter activity
CRN74_00685	COG1136	(ABC) transporter
CRN74_00690	COG1538	Outer membrane efflux protein
CRN74_00710	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_00730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CRN74_00735	COG4948	Mandelate Racemase Muconate Lactonizing
CRN74_00740	COG0747	negative chemotaxis
CRN74_00745	COG0601	transmembrane transport
CRN74_00755	COG0444	Belongs to the ABC transporter superfamily
CRN74_00760	COG4608	Belongs to the ABC transporter superfamily
CRN74_00765	COG0583	DNA-binding transcription factor activity
CRN74_00770	COG2610	gluconate transmembrane transporter activity
CRN74_00775	COG3048	D-serine ammonia-lyase activity
CRN74_00785	COG0765	amino acid transport
CRN74_00790	COG0765	amino acid transport
CRN74_00795	COG1126	abc transporter atp-binding protein
CRN74_00800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRN74_00815	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CRN74_00820	COG0640	Transcriptional regulator
CRN74_00875	COG0410	ABC transporter
CRN74_00880	COG1137	ATPase activity
CRN74_00885	COG4177	L-phenylalanine transmembrane transporter activity
CRN74_00890	COG0559	Belongs to the binding-protein-dependent transport system permease family
CRN74_00900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CRN74_00900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CRN74_00905	COG1070	Carbohydrate kinase
CRN74_00910	COG3623	hexulose-6-phosphate isomerase
CRN74_00920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_00925	COG1129	ABC transporter
CRN74_00935	COG1349	DNA-binding transcription factor activity
CRN74_00945	COG1349	DNA-binding transcription factor activity
CRN74_00955	COG1070	Carbohydrate kinase
CRN74_00965	COG0738	Major facilitator superfamily
CRN74_00970	COG0235	Class ii aldolase
CRN74_00975	COG1454	alcohol dehydrogenase
CRN74_00980	COG0243	molybdopterin cofactor binding
CRN74_00985	COG0437	4 iron, 4 sulfur cluster binding
CRN74_00990	COG3302	dmso reductase anchor subunit
CRN74_00995	COG3381	protein complex oligomerization
CRN74_01020	COG1129	ABC transporter
CRN74_01025	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_01030	COG3959	Transketolase, thiamine diphosphate binding domain
CRN74_01035	COG3958	Transketolase
CRN74_01040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CRN74_01065	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CRN74_01070	COG2137	regulation of response to DNA damage stimulus
CRN74_01075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CRN74_01080	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CRN74_01105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN74_01110	COG1238	metal cluster binding
CRN74_01115	COG2918	glutathione biosynthetic process
CRN74_01120	COG1854	S-ribosylhomocysteine lyase activity
CRN74_01125	COG4536	flavin adenine dinucleotide binding
CRN74_01130	COG4137	Cytochrome C assembly protein
CRN74_01135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CRN74_01145	COG0228	four-way junction DNA binding
CRN74_01150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CRN74_01160	COG0335	large ribosomal subunit rRNA binding
CRN74_01165	COG3137	Salt-induced outer membrane protein
CRN74_01170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CRN74_01175	COG3279	Response regulator of the LytR AlgR family
CRN74_01180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CRN74_01185	COG0287	Prephenate dehydrogenase
CRN74_01185	COG1605	Chorismate mutase
CRN74_01190	COG1605	Chorismate mutase
CRN74_01190	COG0077	Prephenate dehydratase
CRN74_01195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CRN74_01200	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CRN74_01210	COG0564	pseudouridine synthase activity
CRN74_01220	COG0542	response to heat
CRN74_01255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN74_01260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRN74_01260	COG0045	succinate-CoA ligase (ADP-forming) activity
CRN74_01260	COG1042	CoA-binding domain protein
CRN74_01270	COG3118	belongs to the thioredoxin family
CRN74_01275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRN74_01280	COG2814	Major facilitator Superfamily
CRN74_01285	COG1566	PFAM secretion protein HlyD family protein
CRN74_01290	COG1846	Transcriptional regulator
CRN74_01300	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CRN74_01305	COG2814	Major facilitator Superfamily
CRN74_01310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CRN74_01320	COG0436	Aminotransferase
CRN74_01325	COG0235	Class ii aldolase
CRN74_01335	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CRN74_01345	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CRN74_01360	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CRN74_01365	COG1960	acyl-CoA dehydrogenase activity
CRN74_01375	COG0121	glutamine amidotransferase
CRN74_01380	COG3034	peptidoglycan biosynthetic process
CRN74_01385	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CRN74_01390	COG1805	sodium ion transport
CRN74_01395	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CRN74_01400	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CRN74_01405	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CRN74_01410	COG2871	sodium ion transport
CRN74_01415	COG1477	protein flavinylation
CRN74_01420	COG2991	Protein conserved in bacteria
CRN74_01430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CRN74_01435	COG2195	Cleaves the N-terminal amino acid of tripeptides
CRN74_01455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CRN74_01460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CRN74_01470	COG3459	Glycosyltransferase 36 associated
CRN74_01485	COG2226	methyltransferase
CRN74_01500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CRN74_01505	COG3123	guanosine phosphorylase activity
CRN74_01510	COG2974	May be involved in recombination
CRN74_01515	COG1940	carbohydrate kinase activity
CRN74_01520	COG0419	ATPase involved in DNA repair
CRN74_01525	COG0420	3'-5' exonuclease activity
CRN74_01530	COG0745	RESPONSE REGULATOR receiver
CRN74_01535	COG5002	protein histidine kinase activity
CRN74_01545	COG1114	Component of the transport system for branched-chain amino acids
CRN74_01555	COG0366	Alpha amylase catalytic
CRN74_01570	COG0450	alkyl hydroperoxide reductase
CRN74_01575	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CRN74_01580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CRN74_01585	COG0343	queuine tRNA-ribosyltransferase activity
CRN74_01590	COG1862	Preprotein translocase
CRN74_01595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CRN74_01600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CRN74_01610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CRN74_01615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRN74_01615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRN74_01630	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CRN74_01635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CRN74_01640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CRN74_01645	COG0142	geranyltranstransferase activity
CRN74_01655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRN74_01655	COG0301	tRNA thio-modification
CRN74_01660	COG0693	protein deglycase activity
CRN74_01665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CRN74_01675	COG1666	GTP binding
CRN74_01680	COG2814	Major facilitator Superfamily
CRN74_01685	COG0109	protoheme IX farnesyltransferase activity
CRN74_01690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CRN74_01695	COG1845	cytochrome c oxidase, subunit III
CRN74_01700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CRN74_01705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CRN74_01715	COG2223	nitrite transmembrane transporter activity
CRN74_01720	COG3056	Lipoprotein
CRN74_01725	COG0271	Belongs to the BolA IbaG family
CRN74_01735	COG0544	peptidyl-prolyl cis-trans isomerase activity
CRN74_01740	COG0740	serine-type endopeptidase activity
CRN74_01745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CRN74_01750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CRN74_01755	COG0776	regulation of translation
CRN74_01760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN74_01765	COG1555	photosystem II stabilization
CRN74_01770	COG0824	Thioesterase
CRN74_01775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CRN74_01780	COG4533	DNA binding
CRN74_01785	COG0561	phosphatase activity
CRN74_01795	COG1522	sequence-specific DNA binding
CRN74_01800	COG1132	(ABC) transporter
CRN74_01805	COG1132	(ABC) transporter
CRN74_01810	COG0347	Belongs to the P(II) protein family
CRN74_01815	COG0004	ammonium transporteR
CRN74_01820	COG1946	Acyl-CoA thioesterase
CRN74_01825	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CRN74_01830	COG3695	enzyme binding
CRN74_01870	COG1121	(ABC) transporter
CRN74_01875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN74_01880	COG0803	Belongs to the bacterial solute-binding protein 9 family
CRN74_01885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CRN74_01890	COG0254	rRNA binding
CRN74_01895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CRN74_01900	COG3457	Alanine racemase
CRN74_01910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN74_01915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_01920	COG1309	transcriptional regulator
CRN74_01925	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CRN74_01930	COG1196	nuclear chromosome segregation
CRN74_01930	COG3264	Mechanosensitive ion channel
CRN74_01945	COG2832	Protein of unknown function (DUF454)
CRN74_01950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CRN74_01965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CRN74_01970	COG0326	Molecular chaperone. Has ATPase activity
CRN74_01975	COG0563	adenylate kinase activity
CRN74_01980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CRN74_02010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN74_02025	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CRN74_02030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN74_02035	COG4651	solute:proton antiporter activity
CRN74_02035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CRN74_02040	COG2223	nitrite transmembrane transporter activity
CRN74_02045	COG0737	Belongs to the 5'-nucleotidase family
CRN74_02050	COG0582	viral genome integration into host DNA
CRN74_02080	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CRN74_02085	COG5532	Uncharacterized conserved protein (DUF2303)
CRN74_02120	COG4197	protein conserved in bacteria, prophage-related
CRN74_02140	COG4725	Belongs to the MT-A70-like family
CRN74_02150	COG3646	Phage regulatory protein
CRN74_02150	COG3645	SOS response
CRN74_02155	COG1403	HNH endonuclease
CRN74_02170	COG3772	lysozyme
CRN74_02200	COG1802	Transcriptional regulator
CRN74_02200	COG4626	Terminase
CRN74_02210	COG0740	serine-type endopeptidase activity
CRN74_02250	COG4386	tail sheath protein
CRN74_02295	COG3778	Protein conserved in bacteria
CRN74_02315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CRN74_02320	COG3735	TraB family
CRN74_02325	COG2217	Heavy metal translocating P-type atpase
CRN74_02335	COG1585	Membrane protein implicated in regulation of membrane protease activity
CRN74_02340	COG0330	HflC and HflK could
CRN74_02345	COG3118	belongs to the thioredoxin family
CRN74_02350	COG0300	oxidoreductase activity
CRN74_02355	COG2755	lipolytic protein G-D-S-L family
CRN74_02360	COG4181	ATPase activity
CRN74_02365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CRN74_02370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CRN74_02375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CRN74_02380	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CRN74_02385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CRN74_02390	COG0215	cysteine-tRNA ligase activity
CRN74_02415	COG3188	usher protein
CRN74_02420	COG3121	Chaperone
CRN74_02430	COG3539	Fimbrial protein
CRN74_02450	COG2501	S4 domain
CRN74_02455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CRN74_02470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CRN74_02560	COG4197	protein conserved in bacteria, prophage-related
CRN74_02625	COG1783	phage Terminase large subunit
CRN74_02755	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CRN74_02780	COG0582	viral genome integration into host DNA
CRN74_02790	COG3064	Membrane
CRN74_02815	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CRN74_02830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRN74_02835	COG2313	pseudouridylate synthase activity
CRN74_02840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN74_02875	COG2979	Protein of unknown function (DUF533)
CRN74_02885	COG0471	metal ion transport
CRN74_02900	COG2850	peptidyl-arginine hydroxylation
CRN74_02905	COG5265	(ABC) transporter
CRN74_02920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CRN74_02930	COG2197	response regulator
CRN74_02935	COG1278	Cold shock
CRN74_02940	COG1278	Cold shock
CRN74_02950	COG3706	GGDEF domain
CRN74_02955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CRN74_02960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CRN74_02965	COG0321	lipoyl(octanoyl) transferase activity
CRN74_02970	COG2921	Belongs to the UPF0250 family
CRN74_02975	COG1686	Belongs to the peptidase S11 family
CRN74_02980	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CRN74_02985	COG0772	Belongs to the SEDS family
CRN74_02990	COG0768	penicillin binding
CRN74_03000	COG0799	negative regulation of ribosome biogenesis
CRN74_03005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CRN74_03010	COG1466	dna polymerase III delta subunit
CRN74_03015	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CRN74_03025	COG2888	peptidyl-tyrosine sulfation
CRN74_03030	COG1126	abc transporter atp-binding protein
CRN74_03035	COG0765	amino acid transport
CRN74_03040	COG0765	amino acid transport
CRN74_03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_03055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CRN74_03060	COG4535	Mg2 and Co2 transporter CorC
CRN74_03065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CRN74_03070	COG1702	phosphate starvation-inducible protein PhoH
CRN74_03075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CRN74_03080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRN74_03115	COG0367	asparagine synthase
CRN74_03120	COG0647	UMP catabolic process
CRN74_03125	COG1940	carbohydrate kinase activity
CRN74_03125	COG1846	Transcriptional regulator
CRN74_03130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CRN74_03140	COG1263	PTS System
CRN74_03140	COG2190	(PTS) system
CRN74_03140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_03145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CRN74_03170	COG0735	belongs to the Fur family
CRN74_03180	COG0840	transmembrane signaling receptor activity
CRN74_03190	COG0596	Alpha beta hydrolase
CRN74_03195	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CRN74_03200	COG0033	Phosphoglucomutase
CRN74_03210	COG0745	RESPONSE REGULATOR receiver
CRN74_03215	COG2205	protein histidine kinase activity
CRN74_03220	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CRN74_03225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CRN74_03230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CRN74_03245	COG3272	Protein of unknown function (DUF1722)
CRN74_03255	COG5212	phosphodiesterase
CRN74_03260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CRN74_03265	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CRN74_03270	COG1984	allophanate hydrolase subunit 2
CRN74_03275	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CRN74_03300	COG2009	succinate dehydrogenase
CRN74_03305	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CRN74_03310	COG1053	succinate dehydrogenase
CRN74_03315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CRN74_03320	COG0567	Dehydrogenase, E1 component
CRN74_03325	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRN74_03335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CRN74_03340	COG0737	Belongs to the 5'-nucleotidase family
CRN74_03345	COG1271	oxidase subunit
CRN74_03350	COG1294	oxidase, subunit
CRN74_03355	COG4890	Cyd operon protein YbgT
CRN74_03360	COG3790	cyd operon protein YbgE
CRN74_03365	COG0824	Thioesterase
CRN74_03370	COG0811	peptide transport
CRN74_03375	COG0848	biopolymer transport protein
CRN74_03380	COG3064	Membrane
CRN74_03380	COG3064	Membrane
CRN74_03385	COG0823	Involved in the tonB-independent uptake of proteins
CRN74_03390	COG2885	chlorophyll binding
CRN74_03395	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CRN74_03425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CRN74_03435	COG1230	cation diffusion facilitator family transporter
CRN74_03440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CRN74_03445	COG0588	phosphoglycerate mutase activity
CRN74_03455	COG2017	converts alpha-aldose to the beta-anomer
CRN74_03460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CRN74_03465	COG1085	galactose-1-phosphate uridylyltransferase
CRN74_03470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CRN74_03480	COG1119	ATPase activity
CRN74_03485	COG3585	molybdate ion transport
CRN74_03485	COG2005	Transcriptional regulator
CRN74_03495	COG0725	ABC transporter, periplasmic molybdate-binding protein
CRN74_03500	COG4149	molybdate abc transporter
CRN74_03510	COG3037	sugar-specific permease SgaT UlaA
CRN74_03520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_03525	COG1609	Transcriptional regulator
CRN74_03530	COG0280	phosphate acetyltransferase
CRN74_03530	COG0857	belongs to the CobB CobQ family
CRN74_03545	COG3092	negative regulation of chromosome organization
CRN74_03550	COG3013	Belongs to the UPF0304 family
CRN74_03555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN74_03565	COG0490	domain, Protein
CRN74_03565	COG0471	metal ion transport
CRN74_03570	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CRN74_03575	COG0436	Aminotransferase
CRN74_03580	COG0583	DNA-binding transcription factor activity
CRN74_03585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN74_03590	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN74_03595	COG0649	NAD binding
CRN74_03595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN74_03600	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CRN74_03610	COG1034	ATP synthesis coupled electron transport
CRN74_03615	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CRN74_03620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN74_03625	COG0839	Belongs to the complex I subunit 6 family
CRN74_03630	COG0713	ATP synthesis coupled electron transport
CRN74_03635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CRN74_03640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN74_03645	COG1007	ATP synthesis coupled electron transport
CRN74_03665	COG2731	YhcH YjgK YiaL family protein
CRN74_03670	COG3265	gluconokinase activity
CRN74_03675	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_03680	COG1609	Transcriptional regulator
CRN74_03685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN74_03695	COG4702	Belongs to the UPF0303 family
CRN74_03700	COG0129	dihydroxy-acid dehydratase activity
CRN74_03705	COG4575	ribosome binding
CRN74_03715	COG1169	isochorismate synthase
CRN74_03720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CRN74_03730	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CRN74_03735	COG1441	menaquinone biosynthetic process
CRN74_03760	COG0814	amino acid
CRN74_03770	COG4574	serine-type endopeptidase inhibitor activity
CRN74_03775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN74_03785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRN74_03800	COG0784	Response regulator, receiver
CRN74_03800	COG2205	protein histidine kinase activity
CRN74_03810	COG2198	Histidine kinase
CRN74_03810	COG0642	Histidine kinase
CRN74_03815	COG2223	nitrite transmembrane transporter activity
CRN74_03830	COG1132	(ABC) transporter
CRN74_03840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CRN74_03855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CRN74_03890	COG3121	Chaperone
CRN74_03910	COG1737	Transcriptional regulator
CRN74_03915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_03915	COG2190	(PTS) system
CRN74_03915	COG1263	PTS System
CRN74_03920	COG2723	6-phospho-beta-galactosidase activity
CRN74_03925	COG3539	Fimbrial protein
CRN74_03930	COG3121	Chaperone
CRN74_03935	COG3188	usher protein
CRN74_03940	COG3539	Fimbrial protein
CRN74_03945	COG3539	Fimbrial protein
CRN74_03950	COG3539	Fimbrial protein
CRN74_03955	COG0657	acetylesterase activity
CRN74_03955	COG2755	lipolytic protein G-D-S-L family
CRN74_03975	COG3082	Protein of unknown function (DUF1414)
CRN74_03980	COG3081	Nucleoid-associated protein
CRN74_03990	COG1061	Type III restriction enzyme res subunit
CRN74_03995	COG1187	pseudouridine synthase activity
CRN74_04000	COG2814	Major facilitator Superfamily
CRN74_04010	COG4172	Belongs to the ABC transporter superfamily
CRN74_04015	COG4239	(ABC) transporter, permease
CRN74_04020	COG4174	ABC transporter (Permease)
CRN74_04025	COG4166	transmembrane transport
CRN74_04030	COG2200	EAL domain
CRN74_04035	COG0791	NLP P60 protein
CRN74_04040	COG0671	phosphoesterase, PA-phosphatase related
CRN74_04045	COG0523	cobalamin synthesis protein
CRN74_04055	COG2186	Transcriptional regulator
CRN74_04060	COG0246	Mannitol dehydrogenase
CRN74_04070	COG1312	Catalyzes the dehydration of D-mannonate
CRN74_04075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CRN74_04100	COG1105	Belongs to the carbohydrate kinase PfkB family
CRN74_04105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN74_04105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CRN74_04105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN74_04110	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CRN74_04115	COG2855	membrane
CRN74_04125	COG0583	DNA-binding transcription factor activity
CRN74_04130	COG0833	amino acid
CRN74_04135	COG4771	TonB-dependent receptor
CRN74_04140	COG0625	glutathione transferase activity
CRN74_04165	COG2011	ABC-type metal ion transport system permease component
CRN74_04180	COG0626	cystathionine gamma-synthase activity
CRN74_04190	COG1686	Belongs to the peptidase S11 family
CRN74_04195	COG1760	l-serine dehydratase
CRN74_04200	COG0814	amino acid
CRN74_04205	COG1349	DNA-binding transcription factor activity
CRN74_04210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CRN74_04215	COG0671	phosphoesterase, PA-phosphatase related
CRN74_04225	COG0569	domain protein
CRN74_04225	COG2985	domain, Protein
CRN74_04230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CRN74_04245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CRN74_04250	COG3842	ATPase activity
CRN74_04255	COG1176	ABC-type spermidine putrescine transport system, permease component I
CRN74_04260	COG1177	transmembrane transport
CRN74_04275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_04280	COG4160	amino acid transport
CRN74_04285	COG4215	(ABC) transporter
CRN74_04290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_04295	COG1126	abc transporter atp-binding protein
CRN74_04300	COG1605	Chorismate mutase
CRN74_04310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN74_04315	COG0702	epimerase
CRN74_04320	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CRN74_04330	COG0028	Belongs to the TPP enzyme family
CRN74_04335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN74_04340	COG1151	hydroxylamine reductase activity
CRN74_04345	COG2431	L-lysine efflux transmembrane transporter activity
CRN74_04350	COG3593	DNA synthesis involved in DNA repair
CRN74_04355	COG2990	Protein conserved in bacteria
CRN74_04360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_04370	COG1278	Cold shock
CRN74_04375	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CRN74_04380	COG0542	response to heat
CRN74_04385	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CRN74_04390	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CRN74_04395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CRN74_04405	COG0492	ferredoxin-NADP+ reductase activity
CRN74_04415	COG1674	ftsk spoiiie
CRN74_04415	COG3107	peptidoglycan biosynthetic process
CRN74_04420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CRN74_04425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CRN74_04430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CRN74_04435	COG2814	Major facilitator Superfamily
CRN74_04440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CRN74_04445	COG1882	Formate acetyltransferase
CRN74_04450	COG2116	formate transmembrane transporter activity
CRN74_04455	COG1944	ATP diphosphatase activity
CRN74_04460	COG0252	asparaginase activity
CRN74_04465	COG2323	membrane
CRN74_04475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CRN74_04485	COG0539	negative regulation of cytoplasmic translation
CRN74_04490	COG0776	regulation of translation
CRN74_04495	COG0658	competence protein
CRN74_04495	COG2333	competence protein COMEC
CRN74_04510	COG5383	Protein conserved in bacteria
CRN74_04515	COG1278	Cold shock
CRN74_04520	COG2835	tetraacyldisaccharide 4'-kinase activity
CRN74_04530	COG3173	Aminoglycoside phosphotransferase
CRN74_04535	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CRN74_04540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CRN74_04545	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CRN74_04550	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CRN74_04560	COG2989	Protein conserved in bacteria
CRN74_04565	COG3108	Peptidase M15
CRN74_04570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN74_04575	COG2200	EAL domain
CRN74_04580	COG1448	Aminotransferase
CRN74_04590	COG0017	Asparaginyl-tRNA synthetase
CRN74_04595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CRN74_04600	COG0308	aminopeptidase N
CRN74_04605	COG0167	dihydroorotate dehydrogenase activity
CRN74_04615	COG0633	Ferredoxin
CRN74_04615	COG3217	Mosc domain protein beta barrel domain protein
CRN74_04620	COG0116	Belongs to the methyltransferase superfamily
CRN74_04620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRN74_04625	COG0488	(ABC) transporter
CRN74_04630	COG2995	paraquat-inducible protein a
CRN74_04635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CRN74_04635	COG3008	intermembrane lipid transfer
CRN74_04640	COG3009	Protein conserved in bacteria
CRN74_04645	COG3130	regulation of translation
CRN74_04650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRN74_04660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CRN74_04665	COG1067	ATP-dependent peptidase activity
CRN74_04670	COG3120	sequence-specific DNA binding
CRN74_04675	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CRN74_04675	COG2885	chlorophyll binding
CRN74_04680	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
CRN74_04685	COG3070	regulator of competence-specific genes
CRN74_04690	COG1289	transmembrane transporter activity
CRN74_04695	COG3304	Inner membrane component domain
CRN74_04700	COG0210	DNA helicase
CRN74_04705	COG1803	Methylglyoxal synthase
CRN74_04710	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CRN74_04715	COG1832	CoA-binding protein
CRN74_04720	COG3785	DNA binding
CRN74_04725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRN74_04735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CRN74_04745	COG1254	Belongs to the acylphosphatase family
CRN74_04750	COG2920	part of a sulfur-relay system
CRN74_04775	COG0738	Major facilitator superfamily
CRN74_04785	COG1349	DNA-binding transcription factor activity
CRN74_04790	COG1940	carbohydrate kinase activity
CRN74_04795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CRN74_04800	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_04805	COG1129	ABC transporter
CRN74_04810	COG1879	ABC-type sugar transport system periplasmic component
CRN74_04815	COG1737	Transcriptional regulator
CRN74_04820	COG0698	ribose 5-phosphate isomerase
CRN74_04830	COG1263	PTS System
CRN74_04830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_04835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRN74_04840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CRN74_04870	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CRN74_04875	COG0437	4 iron, 4 sulfur cluster binding
CRN74_04880	COG3301	Polysulphide reductase, NrfD
CRN74_04885	COG1138	Cytochrome C-type biogenesis protein
CRN74_04890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRN74_04895	COG3088	subunit of a heme lyase
CRN74_04900	COG4235	cytochrome complex assembly
CRN74_04900	COG3088	subunit of a heme lyase
CRN74_04905	COG2771	luxR family
CRN74_04910	COG3916	Acyl-homoserine-lactone synthase
CRN74_04920	COG3263	regulation of cellular component size
CRN74_04935	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CRN74_04940	COG2943	transferase activity, transferring hexosyl groups
CRN74_04945	COG5645	(Lipo)protein
CRN74_04955	COG3104	oligopeptide transport
CRN74_04960	COG2814	Major facilitator Superfamily
CRN74_04965	COG2259	Doxx family
CRN74_04970	COG1560	Kdo2-lipid A biosynthetic process
CRN74_05005	COG0697	spore germination
CRN74_05015	COG0628	permease
CRN74_05025	COG2197	response regulator
CRN74_05045	COG0418	dihydroorotase activity
CRN74_05050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CRN74_05055	COG1530	ribonuclease E activity
CRN74_05060	COG0564	pseudouridine synthase activity
CRN74_05070	COG1399	metal-binding, possibly nucleic acid-binding protein
CRN74_05075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CRN74_05080	COG0416	fatty acid biosynthetic process
CRN74_05095	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_05105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRN74_05110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRN74_05115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CRN74_05120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CRN74_05125	COG0470	DNA polymerase III
CRN74_05130	COG0084	hydrolase, TatD family'
CRN74_05135	COG1263	PTS System
CRN74_05135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_05140	COG4533	DNA binding
CRN74_05145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CRN74_05150	COG0537	adenosine 5'-monophosphoramidase activity
CRN74_05155	COG5633	Lipoprotein
CRN74_05160	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CRN74_05175	COG3150	esterase
CRN74_05180	COG1252	NADH dehydrogenase
CRN74_05190	COG3134	Outer membrane lipoprotein
CRN74_05195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CRN74_05200	COG4591	ABC-type transport system involved in lipoprotein release permease component
CRN74_05210	COG4591	ABC-type transport system involved in lipoprotein release permease component
CRN74_05215	COG1940	carbohydrate kinase activity
CRN74_05220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CRN74_05230	COG2850	peptidyl-arginine hydroxylation
CRN74_05235	COG2205	protein histidine kinase activity
CRN74_05240	COG0745	RESPONSE REGULATOR receiver
CRN74_05250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRN74_05255	COG2915	High frequency lysogenization protein hflD homolog
CRN74_05260	COG0482	sulfurtransferase activity
CRN74_05270	COG1187	pseudouridine synthase activity
CRN74_05275	COG0538	isocitrate dehydrogenase activity
CRN74_05280	COG0582	viral genome integration into host DNA
CRN74_05305	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CRN74_05325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CRN74_05330	COG4197	protein conserved in bacteria, prophage-related
CRN74_05345	COG4626	Terminase
CRN74_05345	COG1802	Transcriptional regulator
CRN74_05355	COG3645	SOS response
CRN74_05355	COG3646	Phage regulatory protein
CRN74_05360	COG1403	HNH endonuclease
CRN74_05405	COG4626	Terminase
CRN74_05405	COG1802	Transcriptional regulator
CRN74_05415	COG4695	Portal protein
CRN74_05455	COG4386	tail sheath protein
CRN74_05500	COG3299	homolog of phage Mu protein gp47
CRN74_05505	COG3778	Protein conserved in bacteria
CRN74_05540	COG0538	isocitrate dehydrogenase activity
CRN74_05560	COG0561	phosphatase activity
CRN74_05565	COG2223	nitrite transmembrane transporter activity
CRN74_05575	COG3189	MarR family transcriptional regulator
CRN74_05585	COG3493	citrate carrier protein
CRN74_05590	COG4565	transcriptional regulatory protein
CRN74_05595	COG3290	protein histidine kinase activity
CRN74_05600	COG2066	Belongs to the glutaminase family
CRN74_05615	COG1609	Transcriptional regulator
CRN74_05620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRN74_05625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRN74_05625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRN74_05630	COG2723	6-phospho-beta-galactosidase activity
CRN74_05635	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRN74_05645	COG0672	)-iron permease
CRN74_05660	COG1136	(ABC) transporter
CRN74_05660	COG0577	efflux transmembrane transporter activity
CRN74_05670	COG0577	efflux transmembrane transporter activity
CRN74_05670	COG1136	(ABC) transporter
CRN74_05685	COG0500	methyltransferase
CRN74_05685	COG3615	Tellurite resistance protein tehB
CRN74_05700	COG0006	proline dipeptidase activity
CRN74_05705	COG0457	Tetratricopeptide repeat
CRN74_05710	COG1649	PFAM Uncharacterised BCR, COG1649
CRN74_05710	COG0726	polysaccharide deacetylase
CRN74_05715	COG1215	transferase activity, transferring glycosyl groups
CRN74_05720	COG3658	cytochrome
CRN74_05735	COG1702	phosphate starvation-inducible protein PhoH
CRN74_05740	COG0387	Pfam Sodium calcium exchanger
CRN74_05755	COG3850	Histidine kinase
CRN74_05765	COG1294	oxidase, subunit
CRN74_05770	COG1271	oxidase subunit
CRN74_05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN74_05780	COG3866	Pectate lyase
CRN74_05785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CRN74_05790	COG3138	arginine N-succinyltransferase
CRN74_05800	COG3724	N-succinylarginine dihydrolase activity
CRN74_05805	COG2988	succinylglutamate desuccinylase activity
CRN74_05820	COG1228	amidohydrolase
CRN74_05830	COG0402	S-adenosylhomocysteine deaminase activity
CRN74_05845	COG1129	ABC transporter
CRN74_05850	COG4211	Belongs to the binding-protein-dependent transport system permease family
CRN74_05855	COG3443	Belongs to the bacterial solute-binding protein 9 family
CRN74_05865	COG4942	peptidase
CRN74_05875	COG0738	Major facilitator superfamily
CRN74_05880	COG0583	DNA-binding transcription factor activity
CRN74_05885	COG2271	Major facilitator Superfamily
CRN74_05900	COG4670	ketone body catabolic process
CRN74_05905	COG1960	acyl-CoA dehydrogenase activity
CRN74_05910	COG1917	Cupin 2, conserved barrel domain protein
CRN74_05910	COG2207	Transcriptional regulator
CRN74_05915	COG2086	electron transfer activity
CRN74_05920	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CRN74_05925	COG0644	oxidoreductase
CRN74_05930	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CRN74_05935	COG0318	PFAM AMP-dependent synthetase and ligase
CRN74_05940	COG0667	Aldo Keto reductase
CRN74_05965	COG1073	alpha beta
CRN74_05970	COG0288	reversible hydration of carbon dioxide
CRN74_05975	COG0786	glutamate:sodium symporter activity
CRN74_05990	COG3210	domain, Protein
CRN74_06005	COG3210	domain, Protein
CRN74_06010	COG2831	hemolysin activation secretion protein
CRN74_06015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CRN74_06030	COG0012	GTP binding
CRN74_06040	COG0193	aminoacyl-tRNA hydrolase activity
CRN74_06050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CRN74_06060	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CRN74_06065	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CRN74_06070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CRN74_06075	COG2890	protein-(glutamine-N5) methyltransferase activity
CRN74_06080	COG3094	Invasion gene expression up-regulator, SirB
CRN74_06085	COG2912	Transglutaminase-like superfamily
CRN74_06095	COG0659	secondary active sulfate transmembrane transporter activity
CRN74_06100	COG3706	GGDEF domain
CRN74_06115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRN74_06125	COG3381	protein complex oligomerization
CRN74_06135	COG0477	Major facilitator Superfamily
CRN74_06140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRN74_06150	COG0673	inositol 2-dehydrogenase activity
CRN74_06155	COG0728	peptidoglycan biosynthetic process
CRN74_06165	COG3102	Protein conserved in bacteria
CRN74_06170	COG3142	Participates in the control of copper homeostasis
CRN74_06175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CRN74_06185	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CRN74_06190	COG1801	Protein of unknown function DUF72
CRN74_06195	COG1335	isochorismatase
CRN74_06200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CRN74_06205	COG0494	nUDIX hydrolase
CRN74_06210	COG0217	transcriptional regulatory protein
CRN74_06220	COG0632	four-way junction helicase activity
CRN74_06225	COG2255	four-way junction helicase activity
CRN74_06230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN74_06235	COG1121	(ABC) transporter
CRN74_06240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CRN74_06245	COG0739	heme binding
CRN74_06250	COG1560	Kdo2-lipid A biosynthetic process
CRN74_06255	COG0469	pyruvate kinase activity
CRN74_06260	COG1737	Transcriptional regulator
CRN74_06265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CRN74_06270	COG0800	Aldolase
CRN74_06275	COG3397	chitin binding
CRN74_06280	COG2076	Multidrug Resistance protein
CRN74_06285	COG2076	Multidrug Resistance protein
CRN74_06290	COG0251	oxidation-reduction process
CRN74_06295	COG1199	ATP-dependent helicase activity
CRN74_06305	COG3065	identical protein binding
CRN74_06310	COG0318	PFAM AMP-dependent synthetase and ligase
CRN74_06315	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CRN74_06320	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CRN74_06325	COG2894	cell division
CRN74_06330	COG0850	regulation of cytokinetic process
CRN74_06335	COG3100	YcgL domain-containing protein
CRN74_06340	COG0179	Fumarylacetoacetate (FAA) hydrolase
CRN74_06345	COG2983	Belongs to the UPF0260 family
CRN74_06355	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CRN74_06360	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CRN74_06370	COG2186	Transcriptional regulator
CRN74_06375	COG0791	NLP P60 protein
CRN74_06385	COG4139	cobalamin transport
CRN74_06390	COG0386	Belongs to the glutathione peroxidase family
CRN74_06395	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CRN74_06400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CRN74_06405	COG0463	Glycosyl transferase, family 2
CRN74_06415	COG0726	polysaccharide deacetylase
CRN74_06420	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CRN74_06430	COG2076	Multidrug Resistance protein
CRN74_06435	COG0791	NLP P60 protein
CRN74_06440	COG0095	Lipoate-protein ligase
CRN74_06455	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CRN74_06460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CRN74_06460	COG0574	Belongs to the PEP-utilizing enzyme family
CRN74_06470	COG0628	permease
CRN74_06475	COG0277	FAD linked oxidase domain protein
CRN74_06475	COG0247	lactate metabolic process
CRN74_06480	COG2050	protein possibly involved in aromatic compounds catabolism
CRN74_06490	COG0316	Belongs to the HesB IscA family
CRN74_06495	COG0719	Fe-S assembly protein
CRN74_06500	COG0396	ATPase activity
CRN74_06505	COG0719	Fe-S assembly protein
CRN74_06515	COG2166	iron-sulfur cluster assembly
CRN74_06520	COG1388	LysM domain
CRN74_06520	COG1376	ErfK ybiS ycfS ynhG family protein
CRN74_06525	COG4238	major outer membrane lipoprotein
CRN74_06545	COG0534	Mate efflux family protein
CRN74_06550	COG0307	riboflavin synthase, alpha
CRN74_06555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CRN74_06560	COG2814	Major facilitator Superfamily
CRN74_06565	COG0583	DNA-binding transcription factor activity
CRN74_06570	COG1609	Transcriptional regulator
CRN74_06580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CRN74_06585	COG0791	NLP P60 protein
CRN74_06590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CRN74_06595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN74_06600	COG0346	lactoylglutathione lyase activity
CRN74_06605	COG1902	pentaerythritol trinitrate reductase activity
CRN74_06610	COG1309	transcriptional regulator
CRN74_06615	COG2194	sulfuric ester hydrolase activity
CRN74_06620	COG3313	Fe-S protein
CRN74_06625	COG4989	oxidoreductase activity
CRN74_06635	COG1566	PFAM secretion protein HlyD family protein
CRN74_06645	COG1846	Transcriptional regulator
CRN74_06650	COG3133	Outer membrane lipoprotein
CRN74_06655	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CRN74_06660	COG3895	Periplasmic Protein
CRN74_06670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CRN74_06680	COG0625	glutathione transferase activity
CRN74_06700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN74_06705	COG3104	oligopeptide transport
CRN74_06710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRN74_06710	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRN74_06720	COG4172	Belongs to the ABC transporter superfamily
CRN74_06730	COG4171	peptide transport system, permease
CRN74_06735	COG4168	peptide transport system, permease
CRN74_06740	COG4166	transmembrane transport
CRN74_06745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CRN74_06750	COG1842	Phage shock protein A
CRN74_06760	COG1983	PspC domain protein
CRN74_06770	COG3106	COG3106 Predicted ATPase
CRN74_06775	COG3768	UPF0283 membrane protein
CRN74_06795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CRN74_06800	COG4948	Mandelate Racemase Muconate Lactonizing
CRN74_06805	COG2866	Carboxypeptidase
CRN74_06810	COG4166	transmembrane transport
CRN74_06820	COG0037	tRNA processing
CRN74_06825	COG3711	transcriptional antiterminator
CRN74_06830	COG1263	PTS System
CRN74_06830	COG2190	(PTS) system
CRN74_06830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_06835	COG2723	6-phospho-beta-galactosidase activity
CRN74_06840	COG0674	pyruvate-flavodoxin oxidoreductase activity
CRN74_06840	COG1013	pyruvate-flavodoxin oxidoreductase activity
CRN74_06840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CRN74_06840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN74_06850	COG3042	response to heat
CRN74_06860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN74_06865	COG2911	Protein conserved in bacteria
CRN74_06875	COG3784	Protein of unknown function (DUF1318)
CRN74_06885	COG1070	Carbohydrate kinase
CRN74_06890	COG0246	Mannitol dehydrogenase
CRN74_06895	COG2390	Transcriptional regulator
CRN74_06900	COG3423	Transcriptional regulator
CRN74_06910	COG0477	Major facilitator Superfamily
CRN74_06915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CRN74_06920	COG1643	Atp-dependent helicase
CRN74_06925	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CRN74_06935	COG3591	Belongs to the peptidase S1B family
CRN74_06945	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CRN74_06950	COG2205	protein histidine kinase activity
CRN74_06955	COG0745	RESPONSE REGULATOR receiver
CRN74_06965	COG0531	amino acid
CRN74_06980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CRN74_06985	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CRN74_06990	COG0589	response to stress
CRN74_06995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRN74_07000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CRN74_07015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CRN74_07025	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_07050	COG1011	Hydrolase
CRN74_07060	COG0531	amino acid
CRN74_07065	COG0076	glutamate decarboxylase activity
CRN74_07090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CRN74_07105	COG4215	(ABC) transporter
CRN74_07115	COG1522	sequence-specific DNA binding
CRN74_07125	COG0625	glutathione transferase activity
CRN74_07165	COG0477	Major facilitator Superfamily
CRN74_07170	COG4221	oxidoreductase activity
CRN74_07175	COG1742	UPF0060 membrane protein
CRN74_07195	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CRN74_07200	COG1940	carbohydrate kinase activity
CRN74_07205	COG0583	DNA-binding transcription factor activity
CRN74_07210	COG2814	Major facilitator Superfamily
CRN74_07225	COG0114	fumarate hydratase activity
CRN74_07235	COG5339	Protein conserved in bacteria
CRN74_07255	COG1609	Transcriptional regulator
CRN74_07260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_07260	COG1263	PTS System
CRN74_07265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CRN74_07270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CRN74_07275	COG0385	Bile acid
CRN74_07280	COG0673	inositol 2-dehydrogenase activity
CRN74_07290	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_07300	COG1879	ABC-type sugar transport system periplasmic component
CRN74_07310	COG2160	L-arabinose isomerase activity
CRN74_07315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CRN74_07335	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CRN74_07345	COG4657	Part of a membrane complex involved in electron transport
CRN74_07355	COG4656	Part of a membrane complex involved in electron transport
CRN74_07360	COG2207	Transcriptional regulator
CRN74_07360	COG3708	Transcriptional regulator
CRN74_07370	COG4659	FMN binding
CRN74_07380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CRN74_07385	COG0243	molybdopterin cofactor binding
CRN74_07390	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CRN74_07395	COG1966	Carbon starvation protein
CRN74_07400	COG2879	small protein
CRN74_07405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CRN74_07420	COG1349	DNA-binding transcription factor activity
CRN74_07430	COG0235	Class ii aldolase
CRN74_07440	COG0023	Translation Initiation Factor
CRN74_07445	COG0284	orotidine-5'-phosphate decarboxylase activity
CRN74_07460	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CRN74_07465	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CRN74_07470	COG0671	phosphoesterase, PA-phosphatase related
CRN74_07475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CRN74_07480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CRN74_07490	COG4974	Belongs to the 'phage' integrase family
CRN74_07540	COG0582	viral genome integration into host DNA
CRN74_07550	COG0583	DNA-binding transcription factor activity
CRN74_07555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRN74_07570	COG0616	signal peptide processing
CRN74_07575	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_07585	COG1187	pseudouridine synthase activity
CRN74_07595	COG2197	response regulator
CRN74_07605	COG0009	L-threonylcarbamoyladenylate synthase
CRN74_07610	COG0613	PHP domain protein
CRN74_07620	COG0512	Glutamine amidotransferase of anthranilate synthase
CRN74_07630	COG0134	indole-3-glycerol-phosphate synthase activity
CRN74_07630	COG0135	phosphoribosylanthranilate isomerase activity
CRN74_07635	COG0133	tryptophan synthase activity
CRN74_07640	COG0159	tryptophan synthase activity
CRN74_07650	COG3047	cAMP biosynthetic process
CRN74_07665	COG2917	probably involved in intracellular septation
CRN74_07670	COG1607	acyl-coa hydrolase
CRN74_07675	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CRN74_07685	COG2350	Protein conserved in bacteria
CRN74_07695	COG2200	EAL domain
CRN74_07705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN74_07710	COG3099	Belongs to the UPF0263 family
CRN74_07715	COG4608	Belongs to the ABC transporter superfamily
CRN74_07720	COG0444	Belongs to the ABC transporter superfamily
CRN74_07725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRN74_07740	COG4166	transmembrane transport
CRN74_07745	COG2095	MarC family integral membrane protein
CRN74_07750	COG1012	belongs to the aldehyde dehydrogenase family
CRN74_07750	COG1454	alcohol dehydrogenase
CRN74_07755	COG1435	thymidine kinase activity
CRN74_07760	COG2916	Histone family protein nucleoid-structuring protein H-NS
CRN74_07770	COG0745	RESPONSE REGULATOR receiver
CRN74_07775	COG1752	Esterase of the alpha-beta hydrolase superfamily
CRN74_07785	COG3012	SEC-C Motif Domain Protein
CRN74_07790	COG0788	formyltetrahydrofolate deformylase activity
CRN74_07805	COG0583	DNA-binding transcription factor activity
CRN74_07810	COG0708	Exodeoxyribonuclease III
CRN74_07815	COG0494	nUDIX hydrolase
CRN74_07825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRN74_07835	COG0778	Nitroreductase
CRN74_07840	COG0616	signal peptide processing
CRN74_07845	COG0252	asparaginase activity
CRN74_07850	COG1335	isochorismatase
CRN74_07855	COG3139	Protein of unknown function (DUF1315)
CRN74_07885	COG3713	MltA-interacting MipA family protein
CRN74_07895	COG2766	serine protein kinase
CRN74_07900	COG2718	Belongs to the UPF0229 family
CRN74_07910	COG0583	DNA-binding transcription factor activity
CRN74_07920	COG2200	EAL domain
CRN74_07920	COG2202	Pas domain
CRN74_07920	COG2199	diguanylate cyclase activity
CRN74_07925	COG2814	Major facilitator Superfamily
CRN74_07930	COG3111	PFAM Bacterial OB fold (BOF) protein
CRN74_07935	COG0745	RESPONSE REGULATOR receiver
CRN74_07940	COG0642	Histidine kinase
CRN74_07945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CRN74_07950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN74_07955	COG2719	SpoVR family
CRN74_07965	COG4974	Belongs to the 'phage' integrase family
CRN74_08045	COG4695	Portal protein
CRN74_08180	COG0776	regulation of translation
CRN74_08220	COG4249	Peptidase C14 caspase catalytic subunit p20
CRN74_08225	COG1811	Na channel or pump
CRN74_08230	COG1414	Transcriptional regulator
CRN74_08235	COG1129	ABC transporter
CRN74_08240	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_08260	COG1070	Carbohydrate kinase
CRN74_08265	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CRN74_08270	COG3623	hexulose-6-phosphate isomerase
CRN74_08295	COG0803	Belongs to the bacterial solute-binding protein 9 family
CRN74_08300	COG1121	(ABC) transporter
CRN74_08305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN74_08310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN74_08325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN74_08330	COG1917	Cupin 2, conserved barrel domain protein
CRN74_08335	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_08350	COG1175	transmembrane transport
CRN74_08355	COG0395	ABC-type sugar transport system, permease component
CRN74_08360	COG3842	ATPase activity
CRN74_08370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CRN74_08375	COG1988	membrane-bound metal-dependent
CRN74_08385	COG3023	N-Acetylmuramoyl-L-alanine amidase
CRN74_08395	COG0823	Involved in the tonB-independent uptake of proteins
CRN74_08400	COG2814	Major facilitator Superfamily
CRN74_08405	COG0501	Belongs to the peptidase M48B family
CRN74_08410	COG0793	Belongs to the peptidase S41A family
CRN74_08415	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CRN74_08420	COG1956	GAF domain-containing protein
CRN74_08425	COG2995	paraquat-inducible protein a
CRN74_08430	COG3008	intermembrane lipid transfer
CRN74_08475	COG3706	GGDEF domain
CRN74_08475	COG4251	negative regulation of phosphorylation
CRN74_08475	COG2203	Gaf domain
CRN74_08475	COG5001	Diguanylate cyclase
CRN74_08500	COG0625	glutathione transferase activity
CRN74_08535	COG0346	lactoylglutathione lyase activity
CRN74_08665	COG3772	lysozyme
CRN74_08710	COG4725	Belongs to the MT-A70-like family
CRN74_08720	COG2974	May be involved in recombination
CRN74_08900	COG1276	copper resistance
CRN74_08905	COG2372	response to copper ion
CRN74_08910	COG1528	Iron-storage protein
CRN74_08925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN74_08930	COG1770	oligopeptidase
CRN74_08945	COG3141	response to X-ray
CRN74_08950	COG0513	Belongs to the DEAD box helicase family
CRN74_08955	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CRN74_08960	COG3140	Belongs to the UPF0181 family
CRN74_08970	COG0494	nUDIX hydrolase
CRN74_08975	COG1760	l-serine dehydratase
CRN74_08985	COG1253	flavin adenine dinucleotide binding
CRN74_08990	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_08990	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_08995	COG3715	PTS system
CRN74_09000	COG3716	PTS system mannose fructose sorbose family IID component
CRN74_09010	COG1971	Probably functions as a manganese efflux pump
CRN74_09020	COG3447	MASE1 domain protein
CRN74_09020	COG5001	Diguanylate cyclase
CRN74_09020	COG5002	protein histidine kinase activity
CRN74_09035	COG0768	penicillin binding
CRN74_09045	COG1278	Cold shock
CRN74_09060	COG1113	amino acid transport
CRN74_09095	COG2207	Transcriptional regulator
CRN74_09110	COG1132	(ABC) transporter
CRN74_09120	COG5001	Diguanylate cyclase
CRN74_09120	COG4251	negative regulation of phosphorylation
CRN74_09120	COG3706	GGDEF domain
CRN74_09120	COG2203	Gaf domain
CRN74_09145	COG0697	spore germination
CRN74_09150	COG2271	Major facilitator Superfamily
CRN74_09155	COG1802	Transcriptional regulator
CRN74_09160	COG1063	alcohol dehydrogenase
CRN74_09165	COG0246	Mannitol dehydrogenase
CRN74_09175	COG1733	regulation of RNA biosynthetic process
CRN74_09180	COG0702	epimerase
CRN74_09185	COG2873	o-acetylhomoserine
CRN74_09195	COG0840	transmembrane signaling receptor activity
CRN74_09225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRN74_09230	COG1737	Transcriptional regulator
CRN74_09235	COG3069	C4-dicarboxylate transmembrane transporter activity
CRN74_09270	COG3778	Protein conserved in bacteria
CRN74_09300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CRN74_09305	COG0322	excinuclease ABC activity
CRN74_09310	COG2197	response regulator
CRN74_09320	COG3136	membrane protein required for alginate biosynthesis
CRN74_09330	COG0366	Alpha amylase catalytic
CRN74_09345	COG2264	protein methyltransferase activity
CRN74_09355	COG1113	amino acid transport
CRN74_09360	COG1309	transcriptional regulator
CRN74_09370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN74_09375	COG1335	isochorismatase
CRN74_09380	COG0251	oxidation-reduction process
CRN74_09385	COG2267	carboxylic ester hydrolase activity
CRN74_09390	COG0778	Nitroreductase
CRN74_09395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CRN74_09400	COG2233	PERMEase
CRN74_09405	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CRN74_09440	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CRN74_09440	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CRN74_09440	COG0506	proline dehydrogenase activity
CRN74_09470	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CRN74_09480	COG1191	sigma factor activity
CRN74_09515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CRN74_09520	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CRN74_09525	COG1677	Flagellar hook-basal body complex protein FliE
CRN74_09535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CRN74_09540	COG1317	bacterial-type flagellum organization
CRN74_09545	COG1157	protein secretion by the type III secretion system
CRN74_09550	COG2882	bacterial-type flagellum organization
CRN74_09580	COG1338	Plays a role in the flagellum-specific transport system
CRN74_09600	COG1256	bacterial-type flagellum assembly
CRN74_09620	COG4786	Flagellar basal body rod
CRN74_09630	COG1749	Flagellar hook protein flgE
CRN74_09635	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CRN74_09640	COG1558	bacterial-type flagellum-dependent cell motility
CRN74_09645	COG1815	bacterial-type flagellum-dependent cell motility
CRN74_09655	COG2747	anti-sigma28 factor FlgM
CRN74_09660	COG3418	PFAM FlgN family protein
CRN74_09670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CRN74_09675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CRN74_09680	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CRN74_09685	COG0745	RESPONSE REGULATOR receiver
CRN74_09695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CRN74_09700	COG0840	transmembrane signaling receptor activity
CRN74_09705	COG0840	transmembrane signaling receptor activity
CRN74_09710	COG0835	chemotaxis
CRN74_09715	COG0643	Histidine kinase
CRN74_09715	COG2198	Histidine kinase
CRN74_09740	COG0589	response to stress
CRN74_09745	COG2130	NADP-dependent
CRN74_09755	COG1285	pathogenesis
CRN74_09760	COG0840	transmembrane signaling receptor activity
CRN74_09770	COG1278	Cold shock
CRN74_09775	COG1609	Transcriptional regulator
CRN74_09780	COG3250	beta-galactosidase activity
CRN74_09785	COG0604	alcohol dehydrogenase
CRN74_09785	COG3321	synthase
CRN74_09785	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_09815	COG3228	Belongs to the MtfA family
CRN74_09850	COG0583	DNA-binding transcription factor activity
CRN74_09875	COG3615	Tellurite resistance protein tehB
CRN74_09880	COG0446	pyridine nucleotide-disulphide oxidoreductase
CRN74_09930	COG3122	Protein conserved in bacteria
CRN74_09940	COG0583	DNA-binding transcription factor activity
CRN74_09945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CRN74_09950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CRN74_09955	COG0471	metal ion transport
CRN74_09965	COG3366	ferrous iron transmembrane transporter activity
CRN74_09970	COG0700	Nucleoside recognition
CRN74_09990	COG0471	metal ion transport
CRN74_10005	COG3051	citrate lyase alpha subunit
CRN74_10010	COG2301	Belongs to the HpcH HpaI aldolase family
CRN74_10015	COG3052	prosthetic group binding
CRN74_10025	COG3290	protein histidine kinase activity
CRN74_10030	COG4565	transcriptional regulatory protein
CRN74_10045	COG2271	Major facilitator Superfamily
CRN74_10050	COG1840	ABC-type Fe3 transport system, periplasmic component
CRN74_10060	COG3842	ATPase activity
CRN74_10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_10075	COG2205	protein histidine kinase activity
CRN74_10085	COG3121	Chaperone
CRN74_10100	COG3121	Chaperone
CRN74_10105	COG1187	pseudouridine synthase activity
CRN74_10145	COG3550	peptidyl-serine autophosphorylation
CRN74_10150	COG3550	peptidyl-serine autophosphorylation
CRN74_10155	COG4221	oxidoreductase activity
CRN74_10160	COG0784	Response regulator, receiver
CRN74_10160	COG0835	chemotaxis
CRN74_10165	COG0534	Mate efflux family protein
CRN74_10170	COG0137	argininosuccinate synthase activity
CRN74_10175	COG2211	Major facilitator Superfamily
CRN74_10180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CRN74_10190	COG0583	DNA-binding transcription factor activity
CRN74_10195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CRN74_10215	COG1492	cobalamin metabolic process
CRN74_10265	COG2875	Belongs to the precorrin methyltransferase family
CRN74_10275	COG2241	protein methyltransferase activity
CRN74_10280	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CRN74_10290	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CRN74_10310	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CRN74_10345	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CRN74_10375	COG1012	belongs to the aldehyde dehydrogenase family
CRN74_10385	COG4656	Part of a membrane complex involved in electron transport
CRN74_10395	COG4810	utilization protein
CRN74_10405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CRN74_10415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CRN74_10425	COG1879	ABC-type sugar transport system periplasmic component
CRN74_10430	COG1129	ABC transporter
CRN74_10435	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_10445	COG2926	Belongs to the UPF0265 family
CRN74_10450	COG1289	transmembrane transporter activity
CRN74_10460	COG2925	Exonuclease
CRN74_10465	COG0531	amino acid
CRN74_10475	COG0371	Dehydrogenase
CRN74_10480	COG1129	ABC transporter
CRN74_10485	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_10490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN74_10495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CRN74_10500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CRN74_10505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CRN74_10510	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CRN74_10510	COG0131	Imidazoleglycerol-phosphate dehydratase
CRN74_10515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CRN74_10520	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CRN74_10525	COG0107	imidazoleglycerol-phosphate synthase activity
CRN74_10530	COG0140	phosphoribosyl-ATP diphosphatase activity
CRN74_10530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CRN74_10535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CRN74_10540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CRN74_10545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CRN74_10565	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CRN74_10575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CRN74_10600	COG1253	flavin adenine dinucleotide binding
CRN74_10605	COG3069	C4-dicarboxylate transmembrane transporter activity
CRN74_10610	COG2982	Protein involved in outer membrane biogenesis
CRN74_10625	COG0489	protein tyrosine kinase activity
CRN74_10630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN74_10630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN74_10645	COG2814	Major facilitator Superfamily
CRN74_10650	COG1380	Effector of murein hydrolase LrgA
CRN74_10655	COG1346	cytolysis
CRN74_10665	COG0281	malic enzyme
CRN74_10670	COG2949	membrane
CRN74_10680	COG0298	carbon dioxide binding
CRN74_10685	COG0375	protein maturation
CRN74_10690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN74_10695	COG0651	ATP synthesis coupled electron transport
CRN74_10700	COG0650	Formate hydrogenlyase subunit 4
CRN74_10705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CRN74_10710	COG4237	Hydrogenase 4 membrane
CRN74_10715	COG0651	ATP synthesis coupled electron transport
CRN74_10720	COG3261	NADH dehydrogenase
CRN74_10720	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CRN74_10725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN74_10730	COG3260	NADH ubiquinone oxidoreductase 20
CRN74_10740	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CRN74_10745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN74_10750	COG3383	formate dehydrogenase (NAD+) activity
CRN74_10755	COG3604	Transcriptional regulator
CRN74_10760	COG2116	formate transmembrane transporter activity
CRN74_10785	COG2311	Membrane
CRN74_10790	COG0302	gtp cyclohydrolase
CRN74_10795	COG0477	Major facilitator Superfamily
CRN74_10800	COG0583	DNA-binding transcription factor activity
CRN74_10815	COG0477	Major facilitator Superfamily
CRN74_10825	COG0303	'Molybdopterin
CRN74_10835	COG0488	(ABC) transporter
CRN74_10855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CRN74_10875	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CRN74_10890	COG4106	trans-aconitate 2-methyltransferase activity
CRN74_10895	COG0783	Belongs to the Dps family
CRN74_10900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CRN74_10905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_10910	COG0765	amino acid transport
CRN74_10915	COG1126	abc transporter atp-binding protein
CRN74_10925	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CRN74_10930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CRN74_10945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CRN74_10950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CRN74_10970	COG0697	spore germination
CRN74_10980	COG1982	Orn Lys Arg decarboxylase major
CRN74_10985	COG0531	amino acid
CRN74_10995	COG1174	glycine betaine transport
CRN74_11000	COG1125	glycine betaine transport
CRN74_11005	COG1174	glycine betaine transport
CRN74_11010	COG1732	Glycine betaine
CRN74_11025	COG2897	thiosulfate sulfurtransferase activity
CRN74_11035	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CRN74_11045	COG0559	Belongs to the binding-protein-dependent transport system permease family
CRN74_11055	COG4807	Protein conserved in bacteria
CRN74_11070	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CRN74_11080	COG2261	transglycosylase associated protein
CRN74_11090	COG1403	HNH endonuclease
CRN74_11100	COG0277	FAD linked oxidase domain protein
CRN74_11105	COG1686	Belongs to the peptidase S11 family
CRN74_11115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRN74_11120	COG0513	Belongs to the DEAD box helicase family
CRN74_11125	COG1309	transcriptional regulator
CRN74_11130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_11135	COG1131	(ABC) transporter
CRN74_11140	COG0842	Transport permease protein
CRN74_11145	COG0842	Transport permease protein
CRN74_11150	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_11155	COG1535	isochorismatase
CRN74_11155	COG3433	isochorismatase activity
CRN74_11160	COG1021	2,3-dihydroxybenzoate-AMP ligase
CRN74_11165	COG1169	isochorismate synthase
CRN74_11170	COG4592	Periplasmic binding protein
CRN74_11180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRN74_11195	COG4774	siderophore transport
CRN74_11200	COG0670	Belongs to the BI1 family
CRN74_11205	COG0314	molybdopterin synthase activity
CRN74_11210	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CRN74_11215	COG0315	cyclic pyranopterin monophosphate synthase activity
CRN74_11220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CRN74_11225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CRN74_11230	COG4628	conserved protein (DUF2132)
CRN74_11235	COG0556	nucleotide-excision repair
CRN74_11245	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CRN74_11250	COG2226	methyltransferase
CRN74_11255	COG0156	8-amino-7-oxononanoate synthase activity
CRN74_11260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CRN74_11270	COG2706	6-phosphogluconolactonase activity
CRN74_11275	COG0561	phosphatase activity
CRN74_11280	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CRN74_11285	COG0622	Phosphoesterase
CRN74_11295	COG1090	epimerase
CRN74_11300	COG4598	ABC transporter
CRN74_11305	COG4160	amino acid transport
CRN74_11310	COG4215	(ABC) transporter
CRN74_11315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_11320	COG0163	prenyltransferase activity
CRN74_11325	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CRN74_11330	COG1286	toxin biosynthetic process
CRN74_11335	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CRN74_11340	COG0285	dihydrofolate synthase activity
CRN74_11345	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CRN74_11350	COG0586	Pfam SNARE associated Golgi protein
CRN74_11360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CRN74_11380	COG1017	nitric oxide dioxygenase activity
CRN74_11380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN74_11385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRN74_11395	COG4232	protein-disulfide reductase activity
CRN74_11410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CRN74_11420	COG1794	racemase activity, acting on amino acids and derivatives
CRN74_11425	COG0745	RESPONSE REGULATOR receiver
CRN74_11425	COG3706	GGDEF domain
CRN74_11430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRN74_11435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CRN74_11435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN74_11445	COG3101	peptidyl-lysine hydroxylation
CRN74_11450	COG0730	response to heat
CRN74_11455	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CRN74_11465	COG2890	protein-(glutamine-N5) methyltransferase activity
CRN74_11475	COG2840	Smr protein MutS2
CRN74_11485	COG2062	phosphohistidine phosphatase, SixA
CRN74_11495	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRN74_11495	COG1024	Enoyl-CoA hydratase
CRN74_11500	COG0183	Belongs to the thiolase family
CRN74_11505	COG3691	Protein conserved in bacteria
CRN74_11530	COG3088	subunit of a heme lyase
CRN74_11530	COG4235	cytochrome complex assembly
CRN74_11535	COG4235	cytochrome complex assembly
CRN74_11535	COG3088	subunit of a heme lyase
CRN74_11540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRN74_11545	COG1138	Cytochrome C-type biogenesis protein
CRN74_11550	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CRN74_11555	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CRN74_11560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CRN74_11565	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CRN74_11575	COG2116	formate transmembrane transporter activity
CRN74_11585	COG0582	viral genome integration into host DNA
CRN74_11750	COG3772	lysozyme
CRN74_11825	COG0305	Participates in initiation and elongation during chromosome replication
CRN74_11970	COG0243	molybdopterin cofactor binding
CRN74_11975	COG3005	denitrification pathway
CRN74_11980	COG2197	response regulator
CRN74_11985	COG2223	nitrite transmembrane transporter activity
CRN74_11990	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CRN74_11995	COG1140	nitrate reductase beta subunit
CRN74_12000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CRN74_12005	COG2181	nitrate reductase activity
CRN74_12010	COG2197	response regulator
CRN74_12015	COG2198	Histidine kinase
CRN74_12015	COG2205	protein histidine kinase activity
CRN74_12015	COG0784	Response regulator, receiver
CRN74_12015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_12025	COG2095	MarC family integral membrane protein
CRN74_12040	COG0531	amino acid
CRN74_12045	COG0076	glutamate decarboxylase activity
CRN74_12050	COG2226	methyltransferase
CRN74_12055	COG2824	Alkylphosphonate utilization operon protein PhnA
CRN74_12060	COG1695	Transcriptional regulator
CRN74_12070	COG2723	6-phospho-beta-galactosidase activity
CRN74_12075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_12075	COG1263	PTS System
CRN74_12080	COG1609	Transcriptional regulator
CRN74_12085	COG2353	YceI-like domain
CRN74_12090	COG3038	cytochrome b561
CRN74_12105	COG1127	ABC transporter
CRN74_12110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CRN74_12130	COG0531	amino acid
CRN74_12135	COG2951	lytic endotransglycosylase activity
CRN74_12150	COG0243	molybdopterin cofactor binding
CRN74_12155	COG0437	4 iron, 4 sulfur cluster binding
CRN74_12160	COG3302	dmso reductase anchor subunit
CRN74_12190	COG0406	alpha-ribazole phosphatase activity
CRN74_12210	COG1598	PFAM Uncharacterised protein family UPF0150
CRN74_12220	COG3038	cytochrome b561
CRN74_12225	COG0436	Aminotransferase
CRN74_12240	COG3275	phosphorelay sensor kinase activity
CRN74_12245	COG3279	Response regulator of the LytR AlgR family
CRN74_12250	COG2223	nitrite transmembrane transporter activity
CRN74_12260	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CRN74_12265	COG0837	glucose binding
CRN74_12280	COG3961	Belongs to the TPP enzyme family
CRN74_12285	COG0667	Aldo Keto reductase
CRN74_12295	COG1914	H( )-stimulated, divalent metal cation uptake system
CRN74_12305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRN74_12350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CRN74_12380	COG3530	Putative quorum-sensing-regulated virulence factor
CRN74_12385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CRN74_12395	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CRN74_12400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRN74_12405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_12415	COG2190	(PTS) system
CRN74_12420	COG2205	protein histidine kinase activity
CRN74_12425	COG0745	RESPONSE REGULATOR receiver
CRN74_12430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_12460	COG1216	Glycosyl transferase, family 2
CRN74_12495	COG4208	sulfate ABC transporter
CRN74_12500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CRN74_12515	COG1737	Transcriptional regulator
CRN74_12520	COG2731	YhcH YjgK YiaL family protein
CRN74_12535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRN74_12540	COG2837	iron assimilation
CRN74_12550	COG3111	PFAM Bacterial OB fold (BOF) protein
CRN74_12555	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_12580	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_12585	COG1129	ABC transporter
CRN74_12605	COG0456	acetyltransferase
CRN74_12610	COG0408	coproporphyrinogen oxidase activity
CRN74_12625	COG0494	nUDIX hydrolase
CRN74_12630	COG3005	denitrification pathway
CRN74_12635	COG3043	anaerobic respiration
CRN74_12640	COG0243	molybdopterin cofactor binding
CRN74_12645	COG3062	negative regulation of establishment of protein localization
CRN74_12650	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN74_12650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN74_12655	COG2197	response regulator
CRN74_12665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN74_12685	COG3842	ATPase activity
CRN74_12690	COG1175	transmembrane transport
CRN74_12705	COG2197	response regulator
CRN74_12710	COG0583	DNA-binding transcription factor activity
CRN74_12715	COG1393	Belongs to the ArsC family
CRN74_12720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRN74_12725	COG1876	peptidase activity
CRN74_12735	COG0400	carboxylic ester hydrolase activity
CRN74_12740	COG1444	tRNA N-acetyltransferase activity
CRN74_12745	COG2707	UPF0756 membrane protein
CRN74_12750	COG2321	neutral zinc metallopeptidase
CRN74_12755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CRN74_12760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CRN74_12765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRN74_12770	COG2716	regulation of RNA biosynthetic process
CRN74_12775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CRN74_12780	COG0628	permease
CRN74_12785	COG4783	chaperone-mediated protein folding
CRN74_12790	COG1393	Belongs to the ArsC family
CRN74_12795	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CRN74_12800	COG2233	PERMEase
CRN74_12805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CRN74_12815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CRN74_12820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRN74_12830	COG0581	inorganic phosphate transmembrane transporter activity
CRN74_12840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CRN74_12845	COG0248	Ppx GppA phosphatase
CRN74_12855	COG2239	Acts as a magnesium transporter
CRN74_12860	COG5001	Diguanylate cyclase
CRN74_12860	COG3447	MASE1 domain protein
CRN74_12860	COG5002	protein histidine kinase activity
CRN74_12865	COG0443	Heat shock 70 kDa protein
CRN74_12875	COG3121	Chaperone
CRN74_12890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_12900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN74_12905	COG0477	Major facilitator Superfamily
CRN74_12910	COG2205	protein histidine kinase activity
CRN74_12915	COG0745	RESPONSE REGULATOR receiver
CRN74_12920	COG3422	double-strand break repair
CRN74_12930	COG1597	lipid kinase activity
CRN74_12935	COG3730	PTS system glucitol sorbitol-specific
CRN74_12950	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_12955	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_12960	COG1349	DNA-binding transcription factor activity
CRN74_12980	COG0351	phosphomethylpyrimidine kinase
CRN74_12995	COG3121	Chaperone
CRN74_13000	COG3121	Chaperone
CRN74_13010	COG3121	Chaperone
CRN74_13025	COG2197	response regulator
CRN74_13035	COG3710	Transcriptional regulator
CRN74_13045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CRN74_13045	COG0519	Catalyzes the synthesis of GMP from XMP
CRN74_13050	COG0517	IMP dehydrogenase activity
CRN74_13050	COG0516	GMP reductase activity
CRN74_13055	COG1570	exodeoxyribonuclease VII activity
CRN74_13060	COG1645	bacterial-type flagellum-dependent swarming motility
CRN74_13070	COG1160	GTP binding
CRN74_13075	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CRN74_13080	COG2976	Protein conserved in bacteria
CRN74_13095	COG1426	Protein conserved in bacteria
CRN74_13120	COG4953	penicillin-binding protein 1C
CRN74_13125	COG2373	Large extracellular alpha-helical protein
CRN74_13130	COG3468	outer membrane autotransporter barrel domain protein
CRN74_13145	COG2975	iron-sulfur cluster assembly
CRN74_13150	COG0633	Ferredoxin
CRN74_13155	COG0443	Heat shock 70 kDa protein
CRN74_13160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CRN74_13170	COG0822	iron-sulfur transferase activity
CRN74_13180	COG1959	2 iron, 2 sulfur cluster binding
CRN74_13185	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CRN74_13190	COG0483	inositol monophosphate 1-phosphatase activity
CRN74_13195	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CRN74_13200	COG3683	transport system, periplasmic component
CRN74_13205	COG3711	transcriptional antiterminator
CRN74_13210	COG2814	Major facilitator Superfamily
CRN74_13220	COG1017	nitric oxide dioxygenase activity
CRN74_13220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN74_13225	COG2188	Transcriptional regulator
CRN74_13230	COG2188	Transcriptional regulator
CRN74_13240	COG3457	Alanine racemase
CRN74_13245	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CRN74_13260	COG0347	Belongs to the P(II) protein family
CRN74_13265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CRN74_13265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CRN74_13270	COG2204	response regulator
CRN74_13275	COG3170	Tfp pilus assembly protein FimV
CRN74_13280	COG2205	protein histidine kinase activity
CRN74_13295	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CRN74_13300	COG0590	tRNA wobble adenosine to inosine editing
CRN74_13305	COG0560	Phosphoserine phosphatase
CRN74_13310	COG1737	Transcriptional regulator
CRN74_13315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN74_13320	COG0736	holo-[acyl-carrier-protein] synthase activity
CRN74_13325	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CRN74_13330	COG1381	Involved in DNA repair and RecF pathway recombination
CRN74_13345	COG0681	Belongs to the peptidase S26 family
CRN74_13360	COG3086	response to oxidative stress
CRN74_13365	COG3026	antisigma factor binding
CRN74_13380	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CRN74_13385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CRN74_13390	COG0513	Belongs to the DEAD box helicase family
CRN74_13395	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CRN74_13400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CRN74_13405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CRN74_13410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CRN74_13415	COG0497	DNA recombination
CRN74_13420	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CRN74_13430	COG2867	negative regulation of translational initiation
CRN74_13435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CRN74_13470	COG3778	Protein conserved in bacteria
CRN74_13475	COG3299	homolog of phage Mu protein gp47
CRN74_13525	COG4386	tail sheath protein
CRN74_13565	COG0740	serine-type endopeptidase activity
CRN74_13575	COG4626	Terminase
CRN74_13575	COG1802	Transcriptional regulator
CRN74_13630	COG0305	Participates in initiation and elongation during chromosome replication
CRN74_13635	COG1484	DNA-dependent DNA replication
CRN74_13750	COG0582	viral genome integration into host DNA
CRN74_13755	COG0582	viral genome integration into host DNA
CRN74_13770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CRN74_13775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CRN74_13810	COG2963	transposase activity
CRN74_13815	COG3311	Transcriptional regulator
CRN74_13820	COG4983	Phage plasmid primase, P4 family domain protein
CRN74_13850	COG2003	Belongs to the UPF0758 family
CRN74_13870	COG0563	adenylate kinase activity
CRN74_13875	COG0251	oxidation-reduction process
CRN74_13890	COG0789	Transcriptional regulator
CRN74_13905	COG1120	ATPase activity
CRN74_13910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN74_13915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN74_13920	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CRN74_13925	COG4772	TonB-dependent receptor
CRN74_13930	COG3712	iron ion homeostasis
CRN74_13935	COG1595	DNA-templated transcription, initiation
CRN74_13945	COG3394	polysaccharide catabolic process
CRN74_13950	COG2169	Transcriptional regulator
CRN74_13950	COG1917	Cupin 2, conserved barrel domain protein
CRN74_13955	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRN74_13960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRN74_13965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRN74_13970	COG2133	pyrroloquinoline quinone binding
CRN74_13980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CRN74_13985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CRN74_13995	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CRN74_14000	COG4413	Urea transporter
CRN74_14010	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CRN74_14020	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CRN74_14025	COG0804	urea catabolic process
CRN74_14030	COG0832	Belongs to the urease beta subunit family
CRN74_14050	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CRN74_14055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRN74_14065	COG0747	negative chemotaxis
CRN74_14090	COG4575	ribosome binding
CRN74_14100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRN74_14110	COG1780	Probably involved in ribonucleotide reductase function
CRN74_14120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRN74_14130	COG4176	ABC-type proline glycine betaine transport system permease component
CRN74_14135	COG2113	Glycine betaine
CRN74_14145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN74_14155	COG2226	methyltransferase
CRN74_14160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN74_14165	COG0741	lytic transglycosylase activity
CRN74_14165	COG1388	LysM domain
CRN74_14170	COG3021	interspecies interaction between organisms
CRN74_14175	COG0656	L-ascorbic acid biosynthetic process
CRN74_14180	COG0583	DNA-binding transcription factor activity
CRN74_14185	COG2814	Major facilitator Superfamily
CRN74_14220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CRN74_14230	COG2011	ABC-type metal ion transport system permease component
CRN74_14235	COG1464	Belongs to the NlpA lipoprotein family
CRN74_14245	COG1720	tRNA m6t6A37 methyltransferase activity
CRN74_14250	COG0442	prolyl-tRNA aminoacylation
CRN74_14255	COG3015	lipoprotein NlpE involved in copper resistance
CRN74_14265	COG4681	YaeQ
CRN74_14275	COG4568	rho-dependent transcription termination
CRN74_14285	COG0037	tRNA processing
CRN74_14290	COG0346	lactoylglutathione lyase activity
CRN74_14295	COG0825	malonyl-CoA metabolic process
CRN74_14300	COG0587	DNA-directed DNA polymerase activity
CRN74_14305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CRN74_14310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CRN74_14315	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CRN74_14330	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CRN74_14340	COG0750	zinc metalloprotease
CRN74_14345	COG0575	Belongs to the CDS family
CRN74_14350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CRN74_14355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CRN74_14365	COG0528	UMP kinase activity
CRN74_14370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CRN74_14380	COG0024	Methionine aminopeptidase
CRN74_14385	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CRN74_14390	COG2171	N-acyltransferase activity
CRN74_14410	COG0564	pseudouridine synthase activity
CRN74_14415	COG3098	single-species biofilm formation
CRN74_14425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CRN74_14425	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CRN74_14430	COG1611	Belongs to the LOG family
CRN74_14440	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CRN74_14445	COG2363	Small membrane protein
CRN74_14450	COG0583	DNA-binding transcription factor activity
CRN74_14460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRN74_14465	COG2166	iron-sulfur cluster assembly
CRN74_14470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CRN74_14475	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CRN74_14495	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRN74_14500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CRN74_14500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CRN74_14505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CRN74_14510	COG1074	ATP-dependent DNA helicase activity
CRN74_14515	COG1025	Belongs to the peptidase M16 family
CRN74_14520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CRN74_14550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CRN74_14560	COG1051	belongs to the nudix hydrolase family
CRN74_14570	COG3066	DNA modification
CRN74_14575	COG0861	Integral membrane protein TerC family
CRN74_14580	COG0667	Aldo Keto reductase
CRN74_14585	COG5499	transcription regulator containing HTH domain
CRN74_14590	COG0477	Major facilitator Superfamily
CRN74_14595	COG0204	Acyl-transferase
CRN74_14595	COG0318	PFAM AMP-dependent synthetase and ligase
CRN74_14605	COG1609	Transcriptional regulator
CRN74_14610	COG0019	diaminopimelate decarboxylase activity
CRN74_14620	COG0583	DNA-binding transcription factor activity
CRN74_14625	COG2814	Major facilitator Superfamily
CRN74_14630	COG0583	DNA-binding transcription factor activity
CRN74_14670	COG1733	regulation of RNA biosynthetic process
CRN74_14675	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_14685	COG0484	heat shock protein binding
CRN74_14695	COG2271	Major facilitator Superfamily
CRN74_14710	COG1522	sequence-specific DNA binding
CRN74_14715	COG3706	GGDEF domain
CRN74_14735	COG0656	L-ascorbic acid biosynthetic process
CRN74_14755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CRN74_14760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CRN74_14765	COG4974	Belongs to the 'phage' integrase family
CRN74_14770	COG0716	FMN binding
CRN74_14775	COG4452	Inner membrane protein CreD
CRN74_14780	COG2205	protein histidine kinase activity
CRN74_14785	COG0745	RESPONSE REGULATOR receiver
CRN74_14795	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CRN74_14800	COG0354	folic acid binding
CRN74_14805	COG1272	protein, Hemolysin III
CRN74_14810	COG1028	Short-chain dehydrogenase reductase Sdr
CRN74_14815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CRN74_14815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CRN74_14820	COG0509	glycine decarboxylation via glycine cleavage system
CRN74_14825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CRN74_14830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRN74_14835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRN74_14840	COG0006	proline dipeptidase activity
CRN74_14845	COG3079	Belongs to the UPF0149 family
CRN74_14850	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CRN74_14860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CRN74_14865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRN74_14870	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CRN74_14875	COG0583	DNA-binding transcription factor activity
CRN74_14885	COG1279	arginine transmembrane transporter activity
CRN74_14900	COG0191	fructose-bisphosphate aldolase activity
CRN74_14905	COG0126	phosphoglycerate kinase activity
CRN74_14910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CRN74_14915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CRN74_14920	COG0501	Belongs to the peptidase M48B family
CRN74_14935	COG1166	arginine decarboxylase activity
CRN74_14940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CRN74_14955	COG0640	Transcriptional regulator
CRN74_14960	COG3091	SprT-like family
CRN74_14965	COG2356	endonuclease I
CRN74_14970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CRN74_14975	COG0189	ligase activity
CRN74_14980	COG1678	Uncharacterized ACR, COG1678
CRN74_14985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CRN74_14990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CRN74_15000	COG2805	Type II/IV secretion system protein
CRN74_15005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CRN74_15010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CRN74_15015	COG0762	integral membrane protein
CRN74_15020	COG1872	DUF167
CRN74_15025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CRN74_15030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CRN74_15040	COG2066	Belongs to the glutaminase family
CRN74_15045	COG3171	Protein conserved in bacteria
CRN74_15050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CRN74_15055	COG1194	a g-specific adenine glycosylase
CRN74_15065	COG0741	lytic transglycosylase activity
CRN74_15070	COG1982	Orn Lys Arg decarboxylase major
CRN74_15090	COG3188	usher protein
CRN74_15095	COG3121	Chaperone
CRN74_15110	COG3655	Transcriptional regulator
CRN74_15125	COG0583	DNA-binding transcription factor activity
CRN74_15130	COG0814	amino acid
CRN74_15135	COG0626	cystathionine gamma-synthase activity
CRN74_15140	COG1082	Xylose isomerase domain protein TIM barrel
CRN74_15145	COG1653	transport
CRN74_15150	COG0823	Involved in the tonB-independent uptake of proteins
CRN74_15155	COG0673	inositol 2-dehydrogenase activity
CRN74_15170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CRN74_15200	COG0745	RESPONSE REGULATOR receiver
CRN74_15215	COG1987	bacterial-type flagellum assembly
CRN74_15230	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CRN74_15240	COG1580	Controls the rotational direction of flagella during chemotaxis
CRN74_15245	COG3144	bacterial-type flagellum assembly
CRN74_15255	COG1157	protein secretion by the type III secretion system
CRN74_15260	COG1317	bacterial-type flagellum organization
CRN74_15265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CRN74_15270	COG1766	The M ring may be actively involved in energy transduction
CRN74_15275	COG1677	Flagellar hook-basal body complex protein FliE
CRN74_15280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CRN74_15290	COG0745	RESPONSE REGULATOR receiver
CRN74_15300	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CRN74_15350	COG0835	chemotaxis
CRN74_15355	COG0643	Histidine kinase
CRN74_15355	COG2198	Histidine kinase
CRN74_15380	COG1191	sigma factor activity
CRN74_15385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CRN74_15390	COG1256	bacterial-type flagellum assembly
CRN74_15410	COG4786	Flagellar basal body rod
CRN74_15420	COG1749	Flagellar hook protein flgE
CRN74_15425	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CRN74_15430	COG1558	bacterial-type flagellum-dependent cell motility
CRN74_15435	COG1815	bacterial-type flagellum-dependent cell motility
CRN74_15445	COG2747	anti-sigma28 factor FlgM
CRN74_15470	COG2197	response regulator
CRN74_15475	COG0840	transmembrane signaling receptor activity
CRN74_15505	COG4932	domain protein
CRN74_15505	COG2373	Large extracellular alpha-helical protein
CRN74_15505	COG1388	LysM domain
CRN74_15530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRN74_15580	COG4964	Belongs to the GSP D family
CRN74_15650	COG1289	transmembrane transporter activity
CRN74_15665	COG1228	amidohydrolase
CRN74_15725	COG0791	NLP P60 protein
CRN74_15725	COG1388	LysM domain
CRN74_15755	COG2885	chlorophyll binding
CRN74_15810	COG3210	domain, Protein
CRN74_15815	COG2831	hemolysin activation secretion protein
CRN74_15820	COG1124	(ABC) transporter
CRN74_15825	COG0444	Belongs to the ABC transporter superfamily
CRN74_15830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRN74_15835	COG0601	transmembrane transport
CRN74_15840	COG0747	negative chemotaxis
CRN74_15845	COG2226	methyltransferase
CRN74_15850	COG1349	DNA-binding transcription factor activity
CRN74_15865	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_15875	COG3716	PTS system mannose fructose sorbose family IID component
CRN74_15880	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_15885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CRN74_15890	COG2222	sugar isomerase
CRN74_15910	COG0024	Methionine aminopeptidase
CRN74_15915	COG4604	ABC transporter, ATP-binding protein
CRN74_15920	COG4605	iron ion homeostasis
CRN74_15930	COG4607	ABC-type enterochelin transport system periplasmic component
CRN74_15935	COG0477	Major facilitator Superfamily
CRN74_15940	COG1609	Transcriptional regulator
CRN74_15965	COG0477	Major facilitator Superfamily
CRN74_15970	COG4302	ethanolamine ammonia-lyase activity
CRN74_15975	COG4303	Ethanolamine ammonia lyase large subunit
CRN74_15990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_16010	COG0471	metal ion transport
CRN74_16015	COG5001	Diguanylate cyclase
CRN74_16025	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CRN74_16030	COG0309	Hydrogenase expression formation protein (HypE)
CRN74_16035	COG0409	Hydrogenase expression formation protein
CRN74_16040	COG0298	carbon dioxide binding
CRN74_16045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CRN74_16050	COG0375	protein maturation
CRN74_16055	COG1773	rubredoxin
CRN74_16060	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CRN74_16065	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CRN74_16070	COG5557	Pfam Polysulphide reductase, NrfD
CRN74_16075	COG0437	4 iron, 4 sulfur cluster binding
CRN74_16080	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CRN74_16085	COG3133	Outer membrane lipoprotein
CRN74_16100	COG0840	transmembrane signaling receptor activity
CRN74_16105	COG4592	Periplasmic binding protein
CRN74_16115	COG1609	Transcriptional regulator
CRN74_16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN74_16140	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN74_16145	COG1120	ATPase activity
CRN74_16170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_16175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN74_16200	COG4964	Belongs to the GSP D family
CRN74_16250	COG0848	biopolymer transport protein
CRN74_16255	COG0811	peptide transport
CRN74_16260	COG0626	cystathionine gamma-synthase activity
CRN74_16265	COG0586	Pfam SNARE associated Golgi protein
CRN74_16270	COG2207	Transcriptional regulator
CRN74_16275	COG1979	alcohol dehydrogenase
CRN74_16280	COG0656	L-ascorbic acid biosynthetic process
CRN74_16290	COG2132	Multicopper oxidase
CRN74_16300	COG0204	Acyl-transferase
CRN74_16310	COG2249	NAD(P)H dehydrogenase (quinone) activity
CRN74_16315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CRN74_16330	COG0187	DNA topoisomerase II activity
CRN74_16335	COG3150	esterase
CRN74_16340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CRN74_16345	COG3151	Protein conserved in bacteria
CRN74_16350	COG0494	nUDIX hydrolase
CRN74_16355	COG1538	Outer membrane efflux protein
CRN74_16360	COG5463	Belongs to the UPF0441 family
CRN74_16365	COG0754	glutathionylspermidine amidase activity
CRN74_16370	COG3384	dioxygenase
CRN74_16375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CRN74_16385	COG0531	amino acid
CRN74_16390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CRN74_16390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CRN74_16395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CRN74_16400	COG3025	triphosphatase activity
CRN74_16405	COG4991	sh3 domain protein
CRN74_16410	COG0617	tRNA 3'-terminal CCA addition
CRN74_16415	COG1968	undecaprenyl-diphosphatase activity
CRN74_16420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CRN74_16425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CRN74_16430	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CRN74_16440	COG0358	DNA primase activity
CRN74_16445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CRN74_16460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN74_16465	COG1454	alcohol dehydrogenase
CRN74_16480	COG2271	Major facilitator Superfamily
CRN74_16485	COG0800	Aldolase
CRN74_16495	COG3247	response to pH
CRN74_16500	COG1902	pentaerythritol trinitrate reductase activity
CRN74_16500	COG0446	pyridine nucleotide-disulphide oxidoreductase
CRN74_16510	COG2813	Specifically methylates the guanine in position
CRN74_16515	COG1451	nucleotide metabolic process
CRN74_16520	COG0673	inositol 2-dehydrogenase activity
CRN74_16525	COG0861	Integral membrane protein TerC family
CRN74_16530	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CRN74_16540	COG2721	sulfolactate sulfo-lyase activity
CRN74_16545	COG0246	Mannitol dehydrogenase
CRN74_16550	COG1904	glucuronate isomerase
CRN74_16555	COG2271	Major facilitator Superfamily
CRN74_16570	COG0586	Pfam SNARE associated Golgi protein
CRN74_16585	COG4575	ribosome binding
CRN74_16590	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CRN74_16600	COG2259	Doxx family
CRN74_16605	COG0435	Glutathione S-transferase
CRN74_16610	COG0583	DNA-binding transcription factor activity
CRN74_16615	COG1741	Belongs to the pirin family
CRN74_16620	COG1064	alcohol dehydrogenase
CRN74_16655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CRN74_16665	COG0792	nuclease activity
CRN74_16670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CRN74_16675	COG2823	Periplasmic or secreted lipoprotein
CRN74_16680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRN74_16685	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CRN74_16690	COG2198	Histidine kinase
CRN74_16690	COG5002	protein histidine kinase activity
CRN74_16690	COG0784	Response regulator, receiver
CRN74_16695	COG1242	4 iron, 4 sulfur cluster binding
CRN74_16700	COG0069	glutamate synthase activity
CRN74_16700	COG0070	glutamate synthase
CRN74_16700	COG0067	glutamate synthase
CRN74_16705	COG0493	'glutamate synthase
CRN74_16715	COG2969	positive regulation of protein catabolic process
CRN74_16720	COG0625	glutathione transferase activity
CRN74_16730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CRN74_16735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CRN74_16740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CRN74_16745	COG3105	Protein conserved in bacteria
CRN74_16750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRN74_16755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRN74_16760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CRN74_16765	COG5007	Belongs to the BolA IbaG family
CRN74_16770	COG3113	response to antibiotic
CRN74_16775	COG2854	intermembrane phospholipid transfer
CRN74_16780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CRN74_16785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CRN74_16790	COG1127	ABC transporter
CRN74_16795	COG0530	calcium, potassium:sodium antiporter activity
CRN74_16800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CRN74_16800	COG0517	IMP dehydrogenase activity
CRN74_16805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CRN74_16810	COG3117	lipopolysaccharide transmembrane transporter activity
CRN74_16815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CRN74_16820	COG1137	ATPase activity
CRN74_16825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CRN74_16835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_16845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_16850	COG0540	Belongs to the ATCase OTCase family
CRN74_16855	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CRN74_16865	COG2308	Evidence 4 Homologs of previously reported genes of
CRN74_16895	COG0366	Alpha amylase catalytic
CRN74_16900	COG1263	PTS System
CRN74_16900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN74_16905	COG1609	Transcriptional regulator
CRN74_16920	COG3711	transcriptional antiterminator
CRN74_16920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_16935	COG3964	amidohydrolase
CRN74_16965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN74_16970	COG3783	Cytochrome b(562)
CRN74_16980	COG0312	modulator of DNA gyrase
CRN74_16985	COG3028	Belongs to the UPF0307 family
CRN74_16990	COG2732	(Barnase) inhibitor
CRN74_17005	COG1289	transmembrane transporter activity
CRN74_17010	COG1566	PFAM secretion protein HlyD family protein
CRN74_17020	COG0583	DNA-binding transcription factor activity
CRN74_17045	COG0312	modulator of DNA gyrase
CRN74_17050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CRN74_17055	COG3164	Protein of unknown function
CRN74_17060	COG1530	ribonuclease E activity
CRN74_17070	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CRN74_17075	COG1792	Involved in formation and maintenance of cell shape
CRN74_17080	COG1077	Cell shape determining protein MreB Mrl
CRN74_17085	COG2200	EAL domain
CRN74_17085	COG2199	diguanylate cyclase activity
CRN74_17090	COG0604	alcohol dehydrogenase
CRN74_17100	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CRN74_17110	COG0511	ligase activity, forming carbon-carbon bonds
CRN74_17115	COG0439	Biotin carboxylase
CRN74_17120	COG3924	membrane
CRN74_17125	COG4145	pantothenate transmembrane transporter activity
CRN74_17130	COG2264	protein methyltransferase activity
CRN74_17135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRN74_17140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CRN74_17150	COG3706	GGDEF domain
CRN74_17150	COG0745	RESPONSE REGULATOR receiver
CRN74_17155	COG3133	Outer membrane lipoprotein
CRN74_17165	COG1278	Cold shock
CRN74_17170	COG1278	Cold shock
CRN74_17175	COG0471	metal ion transport
CRN74_17185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CRN74_17195	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_17200	COG1129	ABC transporter
CRN74_17210	COG1560	Kdo2-lipid A biosynthetic process
CRN74_17220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_17225	COG4597	amino acid ABC transporter
CRN74_17230	COG0765	amino acid transport
CRN74_17235	COG1126	abc transporter atp-binding protein
CRN74_17245	COG1380	Effector of murein hydrolase LrgA
CRN74_17250	COG0583	DNA-binding transcription factor activity
CRN74_17255	COG0025	NhaP-type Na H and K H
CRN74_17260	COG2252	PERMEase
CRN74_17280	COG0629	single-stranded DNA binding
CRN74_17285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CRN74_17290	COG2315	Protein conserved in bacteria
CRN74_17295	COG1448	Aminotransferase
CRN74_17300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CRN74_17305	COG0305	Participates in initiation and elongation during chromosome replication
CRN74_17320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRN74_17330	COG0735	belongs to the Fur family
CRN74_17335	COG3237	CsbD-like
CRN74_17340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CRN74_17345	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CRN74_17350	COG2937	Belongs to the GPAT DAPAT family
CRN74_17360	COG3161	chorismate lyase activity
CRN74_17370	COG4580	involved in the transport of maltose and maltodextrins
CRN74_17385	COG2182	Extracellular solute-binding protein
CRN74_17390	COG1175	transmembrane transport
CRN74_17395	COG3833	ABC-type maltose transport systems, permease component
CRN74_17410	COG0527	aspartate kinase activity
CRN74_17420	COG1410	methionine synthase
CRN74_17420	COG0646	methionine synthase
CRN74_17425	COG1414	Transcriptional regulator
CRN74_17430	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CRN74_17435	COG2224	Isocitrate lyase
CRN74_17440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CRN74_17445	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CRN74_17480	COG0151	Belongs to the GarS family
CRN74_17495	COG3068	Protein conserved in bacteria
CRN74_17500	COG1515	deoxyribonuclease V activity
CRN74_17510	COG2816	NAD+ diphosphatase activity
CRN74_17515	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CRN74_17520	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CRN74_17530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CRN74_17535	COG2104	thiamine diphosphate biosynthetic process
CRN74_17550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CRN74_17555	COG0085	RNA polymerase activity
CRN74_17560	COG0222	ribosome binding
CRN74_17565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CRN74_17575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CRN74_17580	COG0250	Participates in transcription elongation, termination and antitermination
CRN74_17585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CRN74_17620	COG1072	(Pantothenic acid kinase))
CRN74_17625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CRN74_17625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CRN74_17660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CRN74_17665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CRN74_17670	COG0009	L-threonylcarbamoyladenylate synthase
CRN74_17675	COG0551	DNA topoisomerase type I activity
CRN74_17685	COG0758	DNA mediated transformation
CRN74_17690	COG0242	peptide deformylase activity
CRN74_17695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CRN74_17700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CRN74_17700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CRN74_17705	COG0569	domain protein
CRN74_17710	COG1970	mechanosensitive ion channel activity
CRN74_17715	COG3036	rescue of stalled ribosome
CRN74_17720	COG0789	Transcriptional regulator
CRN74_17730	COG0203	ribosomal protein L17
CRN74_17740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CRN74_17745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CRN74_17750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CRN74_17755	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CRN74_17760	COG0201	protein transport
CRN74_17765	COG0200	Binds to the 23S rRNA
CRN74_17770	COG1841	ribosomal large subunit assembly
CRN74_17775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CRN74_17780	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CRN74_17785	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CRN74_17795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CRN74_17810	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CRN74_17815	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CRN74_17820	COG0255	Belongs to the universal ribosomal protein uL29 family
CRN74_17825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CRN74_17830	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CRN74_17835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CRN74_17840	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CRN74_17850	COG0089	rRNA binding
CRN74_17855	COG0088	Forms part of the polypeptide exit tunnel
CRN74_17860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CRN74_17865	COG0051	transcription antitermination factor activity, RNA binding
CRN74_17880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CRN74_17895	COG0049	tRNA binding
CRN74_17900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CRN74_17905	COG2168	tRNA wobble position uridine thiolation
CRN74_17915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CRN74_17920	COG2964	Protein conserved in bacteria
CRN74_17925	COG0545	Peptidyl-prolyl cis-trans isomerase
CRN74_17935	COG1047	Peptidyl-prolyl cis-trans
CRN74_17940	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CRN74_17950	COG2249	NAD(P)H dehydrogenase (quinone) activity
CRN74_17955	COG0488	(ABC) transporter
CRN74_17965	COG2175	clavaminate synthase activity
CRN74_17970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRN74_17980	COG4521	taurine ABC transporter
CRN74_17995	COG0429	hydrolase of the alpha beta-hydrolase fold
CRN74_18000	COG3089	Belongs to the UPF0270 family
CRN74_18005	COG3954	Phosphoribulokinase
CRN74_18010	COG1765	OsmC-like protein
CRN74_18020	COG1289	transmembrane transporter activity
CRN74_18035	COG1470	cell adhesion involved in biofilm formation
CRN74_18035	COG1388	LysM domain
CRN74_18080	COG0433	COG0433 Predicted ATPase
CRN74_18085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CRN74_18090	COG1486	melibiose metabolic process
CRN74_18100	COG4771	TonB-dependent receptor
CRN74_18110	COG0738	Major facilitator superfamily
CRN74_18115	COG0402	S-adenosylhomocysteine deaminase activity
CRN74_18125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRN74_18130	COG2146	nitrite reductase [NAD(P)H] activity
CRN74_18140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CRN74_18140	COG1648	precorrin-2 dehydrogenase activity
CRN74_18145	COG0180	Tryptophanyl-tRNA synthetase
CRN74_18155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CRN74_18175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CRN74_18180	COG4796	Type ii and iii secretion system protein
CRN74_18205	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CRN74_18210	COG0494	nUDIX hydrolase
CRN74_18220	COG1011	Hydrolase
CRN74_18225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CRN74_18235	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CRN74_18255	COG3188	usher protein
CRN74_18260	COG3121	Chaperone
CRN74_18280	COG0745	RESPONSE REGULATOR receiver
CRN74_18285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN74_18290	COG2183	response to ionizing radiation
CRN74_18295	COG1918	ferrous iron import across plasma membrane
CRN74_18315	COG0596	Alpha beta hydrolase
CRN74_18320	COG1040	competence protein
CRN74_18325	COG0316	Belongs to the HesB IscA family
CRN74_18325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CRN74_18330	COG1640	4-alpha-glucanotransferase
CRN74_18335	COG0058	SHG alpha-glucan phosphorylase activity
CRN74_18340	COG2909	trisaccharide binding
CRN74_18355	COG0705	Rhomboid family
CRN74_18360	COG1349	DNA-binding transcription factor activity
CRN74_18365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CRN74_18370	COG0058	SHG alpha-glucan phosphorylase activity
CRN74_18375	COG0297	glycogen (starch) synthase activity
CRN74_18385	COG1523	belongs to the glycosyl hydrolase 13 family
CRN74_18390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CRN74_18395	COG3275	phosphorelay sensor kinase activity
CRN74_18400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CRN74_18405	COG2095	MarC family integral membrane protein
CRN74_18410	COG3265	gluconokinase activity
CRN74_18415	COG2610	gluconate transmembrane transporter activity
CRN74_18420	COG1609	Transcriptional regulator
CRN74_18425	COG1741	Belongs to the pirin family
CRN74_18430	COG1247	-acetyltransferase
CRN74_18435	COG1082	Xylose isomerase domain protein TIM barrel
CRN74_18440	COG0673	inositol 2-dehydrogenase activity
CRN74_18460	COG3718	enzyme involved in inositol metabolism
CRN74_18470	COG2814	Major facilitator Superfamily
CRN74_18480	COG2814	Major facilitator Superfamily
CRN74_18485	COG0583	DNA-binding transcription factor activity
CRN74_18500	COG2197	response regulator
CRN74_18505	COG2081	HI0933 family
CRN74_18510	COG0306	phosphate transporter
CRN74_18520	COG0589	response to stress
CRN74_18535	COG0742	ribosomal rna small subunit methyltransferase
CRN74_18550	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CRN74_18555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN74_18560	COG1295	ribonuclease BN
CRN74_18565	COG2134	cdp-diacylglycerol pyrophosphatase
CRN74_18570	COG2982	Protein involved in outer membrane biogenesis
CRN74_18575	COG2200	EAL domain
CRN74_18580	COG1942	4-Oxalocrotonate Tautomerase
CRN74_18590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN74_18595	COG0612	Peptidase, M16
CRN74_18605	COG1301	dicarboxylic acid transport
CRN74_18610	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CRN74_18615	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CRN74_18620	COG1561	YicC-like family, N-terminal region
CRN74_18640	COG4529	Protein conserved in bacteria
CRN74_18720	COG0305	Participates in initiation and elongation during chromosome replication
CRN74_18775	COG0582	viral genome integration into host DNA
CRN74_18785	COG2207	Transcriptional regulator
CRN74_18785	COG1609	Transcriptional regulator
CRN74_18790	COG4214	carbohydrate transport
CRN74_18800	COG4213	ABC transporter substrate-binding protein
CRN74_18805	COG2115	Belongs to the xylose isomerase family
CRN74_18810	COG1070	Carbohydrate kinase
CRN74_18820	COG3121	Chaperone
CRN74_18825	COG3188	usher protein
CRN74_18835	COG1335	isochorismatase
CRN74_18845	COG3274	enterobacterial common antigen metabolic process
CRN74_18850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_18850	COG2213	PTS system mannitol-specific
CRN74_18855	COG0246	Mannitol dehydrogenase
CRN74_18860	COG3722	fumarate hydratase activity
CRN74_18870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN74_18885	COG2258	MOSC domain
CRN74_18890	COG0840	transmembrane signaling receptor activity
CRN74_18900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CRN74_18905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CRN74_18910	COG3383	formate dehydrogenase (NAD+) activity
CRN74_18910	COG0243	molybdopterin cofactor binding
CRN74_18915	COG3383	formate dehydrogenase (NAD+) activity
CRN74_18915	COG0243	molybdopterin cofactor binding
CRN74_18920	COG0437	4 iron, 4 sulfur cluster binding
CRN74_18925	COG2864	formate dehydrogenase
CRN74_18930	COG3058	Necessary for formate dehydrogenase activity
CRN74_18935	COG1921	L-seryl-tRNASec selenium transferase activity
CRN74_18940	COG3276	selenocysteine insertion sequence binding
CRN74_18955	COG0751	glycine-tRNA ligase activity
CRN74_18960	COG0752	glycyl-tRNA synthetase alpha subunit
CRN74_18970	COG2818	Glycosylase
CRN74_18985	COG2885	chlorophyll binding
CRN74_19005	COG0366	Alpha amylase catalytic
CRN74_19010	COG3977	Valine--pyruvate aminotransferase
CRN74_19015	COG0569	domain protein
CRN74_19015	COG2985	domain, Protein
CRN74_19030	COG5645	(Lipo)protein
CRN74_19035	COG0823	Involved in the tonB-independent uptake of proteins
CRN74_19050	COG2423	ornithine cyclodeaminase activity
CRN74_19060	COG0561	phosphatase activity
CRN74_19065	COG0187	DNA topoisomerase II activity
CRN74_19075	COG0592	DNA-directed DNA polymerase activity
CRN74_19080	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CRN74_19090	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CRN74_19095	COG0594	ribonuclease P activity
CRN74_19105	COG0706	membrane insertase activity
CRN74_19110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CRN74_19115	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CRN74_19125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CRN74_19130	COG2011	ABC-type metal ion transport system permease component
CRN74_19135	COG0840	transmembrane signaling receptor activity
CRN74_19140	COG0431	NADPH-dependent FMN reductase
CRN74_19145	COG4191	Histidine kinase
CRN74_19160	COG2252	PERMEase
CRN74_19165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN74_19170	COG0765	amino acid transport
CRN74_19175	COG0765	amino acid transport
CRN74_19180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN74_19185	COG0704	Plays a role in the regulation of phosphate uptake
CRN74_19195	COG0581	inorganic phosphate transmembrane transporter activity
CRN74_19200	COG0573	inorganic phosphate transmembrane transporter activity
CRN74_19205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CRN74_19210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CRN74_19215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CRN74_19220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CRN74_19225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CRN74_19230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CRN74_19235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CRN74_19240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CRN74_19245	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CRN74_19255	COG0356	it plays a direct role in the translocation of protons across the membrane
CRN74_19260	COG3312	ion transport
CRN74_19265	COG0357	Ribosomal RNA small subunit methyltransferase G
CRN74_19270	COG0445	tRNA wobble uridine modification
CRN74_19275	COG0716	FMN binding
CRN74_19280	COG1522	sequence-specific DNA binding
CRN74_19285	COG2502	aspartate--ammonia ligase
CRN74_19295	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CRN74_19300	COG0714	Associated with various cellular activities
CRN74_19305	COG3158	transport of potassium into the cell
CRN74_19310	COG1869	D-ribose catabolic process
CRN74_19320	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_19325	COG1879	ABC-type sugar transport system periplasmic component
CRN74_19330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN74_19335	COG1609	Transcriptional regulator
CRN74_19340	COG0477	Major facilitator Superfamily
CRN74_19345	COG2186	Transcriptional regulator
CRN74_19375	COG1763	Mo-molybdopterin cofactor biosynthetic process
CRN74_19385	COG3084	Protein conserved in bacteria
CRN74_19390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CRN74_19395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CRN74_19400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRN74_19400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRN74_19405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CRN74_19410	COG3078	GTPase activator activity
CRN74_19420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CRN74_19430	COG3852	Histidine kinase
CRN74_19435	COG0174	glutamine synthetase
CRN74_19445	COG1011	Hydrolase
CRN74_19450	COG1295	ribonuclease BN
CRN74_19460	COG0456	acetyltransferase
CRN74_19480	COG2982	Protein involved in outer membrane biogenesis
CRN74_19485	COG2233	PERMEase
CRN74_19490	COG0786	glutamate:sodium symporter activity
CRN74_19495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CRN74_19500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRN74_19505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CRN74_19510	COG1758	RNA polymerase activity
CRN74_19520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CRN74_19525	COG2860	membrane
CRN74_19535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRN74_19540	COG1024	Enoyl-CoA hydratase
CRN74_19545	COG5001	Diguanylate cyclase
CRN74_19550	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CRN74_19555	COG2986	histidine ammonia-lyase
CRN74_19570	COG1764	response to oxidative stress
CRN74_19575	COG2194	sulfuric ester hydrolase activity
CRN74_19580	COG2197	response regulator
CRN74_19585	COG3851	Histidine kinase
CRN74_19590	COG2271	Major facilitator Superfamily
CRN74_19600	COG2831	hemolysin activation secretion protein
CRN74_19610	COG0747	negative chemotaxis
CRN74_19615	COG0601	transmembrane transport
CRN74_19620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRN74_19625	COG0444	Belongs to the ABC transporter superfamily
CRN74_19630	COG4608	Belongs to the ABC transporter superfamily
CRN74_19635	COG2199	diguanylate cyclase activity
CRN74_19635	COG2200	EAL domain
CRN74_19640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CRN74_19650	COG1309	transcriptional regulator
CRN74_19655	COG0756	dUTP diphosphatase activity
CRN74_19660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CRN74_19670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CRN74_19675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CRN74_19680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CRN74_19695	COG1519	Transferase
CRN74_19700	COG0859	PFAM glycosyl transferase family 9
CRN74_19705	COG0859	PFAM glycosyl transferase family 9
CRN74_19710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN74_19715	COG0156	8-amino-7-oxononanoate synthase activity
CRN74_19725	COG2861	carbohydrate metabolic process
CRN74_19730	COG4942	peptidase
CRN74_19735	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CRN74_19740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRN74_19745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CRN74_19750	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CRN74_19755	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CRN74_19760	COG1045	serine acetyltransferase
CRN74_19765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CRN74_19770	COG2169	Transcriptional regulator
CRN74_19770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CRN74_19775	COG2205	protein histidine kinase activity
CRN74_19780	COG0745	RESPONSE REGULATOR receiver
CRN74_19785	COG3678	ATP-independent chaperone mediated protein folding
CRN74_19790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRN74_19800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CRN74_19820	COG3152	Membrane
CRN74_19830	COG0460	homoserine dehydrogenase
CRN74_19830	COG0527	aspartate kinase activity
CRN74_19835	COG0626	cystathionine gamma-synthase activity
CRN74_19840	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CRN74_19845	COG0254	rRNA binding
CRN74_19855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CRN74_19860	COG1609	Transcriptional regulator
CRN74_19865	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CRN74_19870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CRN74_19875	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CRN74_19880	COG1575	Belongs to the MenA family. Type 1 subfamily
CRN74_19885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CRN74_19890	COG3074	FtsZ-dependent cytokinesis
CRN74_19900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CRN74_19905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CRN74_19910	COG1494	fructose-1,6-bisphosphatase
CRN74_19915	COG2814	Major facilitator Superfamily
CRN74_19925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CRN74_19935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CRN74_19940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CRN74_19945	COG0165	Argininosuccinate lyase
CRN74_19950	COG1629	transport
CRN74_19975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN74_19980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CRN74_19980	COG0678	peroxiredoxin activity
CRN74_19990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN74_20005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CRN74_20015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CRN74_20060	COG1879	ABC-type sugar transport system periplasmic component
CRN74_20065	COG1129	ABC transporter
CRN74_20070	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_20075	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_20080	COG0583	DNA-binding transcription factor activity
CRN74_20085	COG3085	chromosome segregation
CRN74_20105	COG3978	acetolactate synthase activity
CRN74_20110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRN74_20115	COG0129	dihydroxy-acid dehydratase activity
CRN74_20120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CRN74_20130	COG0583	DNA-binding transcription factor activity
CRN74_20135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CRN74_20140	COG3121	Chaperone
CRN74_20155	COG3121	Chaperone
CRN74_20165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN74_20180	COG0248	Ppx GppA phosphatase
CRN74_20190	COG3118	belongs to the thioredoxin family
CRN74_20195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CRN74_20200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRN74_20205	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CRN74_20210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CRN74_20215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CRN74_20220	COG1088	dTDP-glucose 4,6-dehydratase activity
CRN74_20225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CRN74_20230	COG0456	acetyltransferase
CRN74_20235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CRN74_20240	COG2244	polysaccharide biosynthetic process
CRN74_20245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CRN74_20260	COG1113	amino acid transport
CRN74_20285	COG3071	HemY protein
CRN74_20290	COG2959	enzyme of heme biosynthesis
CRN74_20295	COG1587	Uroporphyrinogen-III synthase
CRN74_20300	COG0181	hydroxymethylbilane synthase activity
CRN74_20305	COG3072	Adenylate cyclase
CRN74_20315	COG5567	small periplasmic lipoprotein
CRN74_20320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CRN74_20325	COG3159	Protein conserved in bacteria
CRN74_20330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CRN74_20335	COG1011	Hydrolase
CRN74_20340	COG0210	DNA helicase
CRN74_20355	COG5441	Belongs to the UPF0261 family
CRN74_20360	COG5564	TIM-barrel signal transduction protein
CRN74_20370	COG0598	Magnesium transport protein CorA
CRN74_20380	COG2050	protein possibly involved in aromatic compounds catabolism
CRN74_20385	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CRN74_20390	COG0514	ATP-dependent DNA helicase (RecQ)
CRN74_20395	COG1280	lysine exporter protein (LysE YggA)
CRN74_20400	COG1280	lysine exporter protein (LysE YggA)
CRN74_20405	COG2267	carboxylic ester hydrolase activity
CRN74_20410	COG0561	phosphatase activity
CRN74_20415	COG0584	glycerophosphoryl diester phosphodiesterase
CRN74_20420	COG2271	Major facilitator Superfamily
CRN74_20425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CRN74_20435	COG0247	lactate metabolic process
CRN74_20445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CRN74_20450	COG0425	Belongs to the sulfur carrier protein TusA family
CRN74_20460	COG3714	YhhN family
CRN74_20475	COG3776	membrane
CRN74_20480	COG0742	ribosomal rna small subunit methyltransferase
CRN74_20485	COG0552	protein localization to endoplasmic reticulum
CRN74_20485	COG0552	protein localization to endoplasmic reticulum
CRN74_20490	COG2884	Cell division ATP-binding protein ftsE
CRN74_20495	COG2177	Part of the ABC transporter FtsEX involved in
CRN74_20505	COG0456	acetyltransferase
CRN74_20510	COG0683	leucine binding
CRN74_20515	COG0559	Belongs to the binding-protein-dependent transport system permease family
CRN74_20520	COG4177	L-phenylalanine transmembrane transporter activity
CRN74_20525	COG0411	ABC transporter
CRN74_20530	COG0410	ABC transporter
CRN74_20565	COG1653	transport
CRN74_20570	COG1175	transmembrane transport
CRN74_20575	COG0395	ABC-type sugar transport system, permease component
CRN74_20580	COG3842	ATPase activity
CRN74_20585	COG0584	glycerophosphoryl diester phosphodiesterase
CRN74_20590	COG0679	Auxin Efflux Carrier
CRN74_20600	COG0583	DNA-binding transcription factor activity
CRN74_20605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CRN74_20610	COG0412	Dienelactone hydrolase
CRN74_20615	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CRN74_20625	COG1966	Carbon starvation protein
CRN74_20630	COG0586	Pfam SNARE associated Golgi protein
CRN74_20635	COG1322	Protein conserved in bacteria
CRN74_20640	COG2226	methyltransferase
CRN74_20650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CRN74_20655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CRN74_20665	COG0805	protein transport
CRN74_20685	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CRN74_20695	COG0183	Belongs to the thiolase family
CRN74_20700	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRN74_20700	COG1024	Enoyl-CoA hydratase
CRN74_20710	COG1739	Uncharacterized protein family UPF0029
CRN74_20715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CRN74_20770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRN74_20775	COG3162	membrane
CRN74_20780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRN74_20785	COG1301	dicarboxylic acid transport
CRN74_20955	COG0425	Belongs to the sulfur carrier protein TusA family
CRN74_20960	COG3093	addiction module antidote protein HigA
CRN74_20975	COG1595	DNA-templated transcription, initiation
CRN74_20980	COG3712	iron ion homeostasis
CRN74_20985	COG4771	TonB-dependent receptor
CRN74_20990	COG4178	(ABC) transporter
CRN74_20995	COG0612	Peptidase, M16
CRN74_21005	COG3397	chitin binding
CRN74_21015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CRN74_21060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CRN74_21100	COG2205	protein histidine kinase activity
CRN74_21105	COG2197	response regulator
CRN74_21175	COG4789	Type iii secretion
CRN74_21185	COG1157	protein secretion by the type III secretion system
CRN74_21255	COG1196	nuclear chromosome segregation
CRN74_21255	COG3264	Mechanosensitive ion channel
CRN74_21260	COG4774	siderophore transport
CRN74_21270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN74_21275	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CRN74_21280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN74_21285	COG4558	Periplasmic binding protein
CRN74_21290	COG3720	iron ion transport
CRN74_21295	COG4771	TonB-dependent receptor
CRN74_21305	COG0702	epimerase
CRN74_21310	COG3721	Heme iron utilization protein
CRN74_21320	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CRN74_21330	COG0457	Tetratricopeptide repeat
CRN74_21335	COG1215	transferase activity, transferring glycosyl groups
CRN74_21345	COG0489	protein tyrosine kinase activity
CRN74_21360	COG0463	Glycosyl transferase, family 2
CRN74_21390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CRN74_21395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN74_21395	COG0543	2 iron, 2 sulfur cluster binding
CRN74_21410	COG1309	transcriptional regulator
CRN74_21420	COG2084	Dehydrogenase
CRN74_21425	COG1929	Belongs to the glycerate kinase type-1 family
CRN74_21430	COG3835	regulator
CRN74_21435	COG2721	sulfolactate sulfo-lyase activity
CRN74_21440	COG1929	Belongs to the glycerate kinase type-1 family
CRN74_21445	COG2271	Major facilitator Superfamily
CRN74_21450	COG0493	'glutamate synthase
CRN74_21450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN74_21455	COG0493	'glutamate synthase
CRN74_21455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN74_21460	COG3383	formate dehydrogenase (NAD+) activity
CRN74_21465	COG4232	protein-disulfide reductase activity
CRN74_21475	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CRN74_21490	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CRN74_21495	COG0459	protein refolding
CRN74_21510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CRN74_21520	COG2076	Multidrug Resistance protein
CRN74_21530	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CRN74_21535	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CRN74_21540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CRN74_21545	COG1053	succinate dehydrogenase
CRN74_21555	COG3264	Mechanosensitive ion channel
CRN74_21555	COG1511	domain protein
CRN74_21560	COG0688	phosphatidylethanolamine metabolic process
CRN74_21565	COG1162	GTPase activity
CRN74_21570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CRN74_21595	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CRN74_21600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CRN74_21600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CRN74_21605	COG0802	atpase or kinase
CRN74_21620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CRN74_21630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CRN74_21635	COG0330	HflC and HflK could
CRN74_21640	COG0330	HflC and HflK could
CRN74_21645	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CRN74_21655	COG1959	2 iron, 2 sulfur cluster binding
CRN74_21660	COG0557	exoribonuclease II activity
CRN74_21665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRN74_21670	COG1960	acyl-CoA dehydrogenase activity
CRN74_21675	COG3650	response to hydrogen peroxide
CRN74_21680	COG1073	alpha beta
CRN74_21695	COG0360	Binds together with S18 to 16S ribosomal RNA
CRN74_21705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CRN74_21710	COG0359	binds to the 23S rRNA
CRN74_21720	COG3061	Opacity-associated protein A
CRN74_21725	COG0545	Peptidyl-prolyl cis-trans isomerase
CRN74_21735	COG0737	Belongs to the 5'-nucleotidase family
CRN74_21740	COG1218	3'(2'),5'-bisphosphate nucleotidase
CRN74_21745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CRN74_21755	COG1253	flavin adenine dinucleotide binding
CRN74_21760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CRN74_21770	COG2911	Protein conserved in bacteria
CRN74_21775	COG2105	PFAM AIG2 family protein
CRN74_21780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CRN74_21795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CRN74_21815	COG3423	Transcriptional regulator
CRN74_21825	COG0142	geranyltranstransferase activity
CRN74_21835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CRN74_21840	COG0697	spore germination
CRN74_21845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CRN74_21850	COG0642	Histidine kinase
CRN74_21855	COG0745	RESPONSE REGULATOR receiver
CRN74_21860	COG2027	D-alanyl-D-alanine carboxypeptidase
CRN74_21865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN74_21870	COG1534	Rna-binding protein
CRN74_21875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CRN74_21880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CRN74_21885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CRN74_21895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CRN74_21915	COG0195	Participates in both transcription termination and antitermination
CRN74_21925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CRN74_21930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CRN74_21940	COG1185	polyribonucleotide nucleotidyltransferase activity
CRN74_21950	COG0513	Belongs to the DEAD box helicase family
CRN74_21955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN74_21960	COG0814	amino acid
CRN74_21965	COG3681	Belongs to the UPF0597 family
CRN74_21985	COG3153	acetyltransferase
CRN74_21995	COG0531	amino acid
CRN74_22000	COG1982	Orn Lys Arg decarboxylase major
CRN74_22015	COG1653	transport
CRN74_22025	COG0395	ABC-type sugar transport system, permease component
CRN74_22030	COG3842	ATPase activity
CRN74_22045	COG0702	epimerase
CRN74_22050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CRN74_22055	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CRN74_22060	COG3454	Phosphonate metabolism
CRN74_22065	COG4778	phosphonate C-P lyase system protein PhnL
CRN74_22070	COG4107	phosphonate C-P lyase system protein PhnK
CRN74_22075	COG3627	carbon phosphorus lyase activity
CRN74_22080	COG3626	phosphonate metabolism
CRN74_22085	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CRN74_22090	COG3624	Phosphonate C-P lyase system protein PhnG
CRN74_22095	COG2188	Transcriptional regulator
CRN74_22110	COG0602	queuosine metabolic process
CRN74_22130	COG4608	Belongs to the ABC transporter superfamily
CRN74_22135	COG0444	Belongs to the ABC transporter superfamily
CRN74_22145	COG0601	transmembrane transport
CRN74_22155	COG2731	YhcH YjgK YiaL family protein
CRN74_22165	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CRN74_22180	COG2927	DNA polymerase III (CHI subunit)
CRN74_22185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CRN74_22190	COG0795	lipopolysaccharide-transporting ATPase activity
CRN74_22195	COG0795	lipopolysaccharide-transporting ATPase activity
CRN74_22205	COG0582	viral genome integration into host DNA
CRN74_22235	COG0514	ATP-dependent DNA helicase (RecQ)
CRN74_22270	COG0720	synthase
CRN74_22360	COG2771	luxR family
CRN74_22380	COG1396	sequence-specific DNA binding
CRN74_22385	COG3550	peptidyl-serine autophosphorylation
CRN74_22400	COG1830	Aldolase
CRN74_22410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_22415	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN74_22420	COG1129	ABC transporter
CRN74_22425	COG2390	Transcriptional regulator
CRN74_22430	COG1070	Carbohydrate kinase
CRN74_22435	COG0859	PFAM glycosyl transferase family 9
CRN74_22450	COG2235	arginine
CRN74_22455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN74_22460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN74_22470	COG2376	Dihydroxyacetone kinase
CRN74_22475	COG1461	Dihydroxyacetone kinase
CRN74_22480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CRN74_22480	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CRN74_22480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN74_22490	COG2192	nodulation
CRN74_22505	COG0738	Major facilitator superfamily
CRN74_22515	COG3284	Transcriptional regulator
CRN74_22520	COG3706	GGDEF domain
CRN74_22550	COG0667	Aldo Keto reductase
CRN74_22555	COG2813	Specifically methylates the guanine in position
CRN74_22560	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CRN74_22570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CRN74_22575	COG2823	Periplasmic or secreted lipoprotein
CRN74_22585	COG4667	esterase of the alpha-beta hydrolase superfamily
CRN74_22590	COG0084	hydrolase, TatD family'
CRN74_22595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRN74_22600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CRN74_22610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CRN74_22625	COG2026	Addiction module toxin, RelE StbE family
CRN74_22630	COG3726	membrane protein affecting hemolysin expression
CRN74_22635	COG0560	Phosphoserine phosphatase
CRN74_22650	COG0604	alcohol dehydrogenase
CRN74_22665	COG1454	alcohol dehydrogenase
CRN74_22700	COG0488	(ABC) transporter
CRN74_22705	COG2885	chlorophyll binding
CRN74_22710	COG2199	diguanylate cyclase activity
CRN74_22720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CRN74_22725	COG0741	lytic transglycosylase activity
CRN74_22730	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CRN74_22735	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CRN74_22740	COG0406	alpha-ribazole phosphatase activity
CRN74_22745	COG2207	Transcriptional regulator
CRN74_22745	COG3708	Transcriptional regulator
CRN74_22755	COG3045	CreA protein
CRN74_22760	COG0745	RESPONSE REGULATOR receiver
CRN74_22780	COG0083	homoserine kinase activity
CRN74_22790	COG3022	response to hydroperoxide
CRN74_22800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CRN74_22805	COG0521	Mo-molybdopterin cofactor biosynthetic process
CRN74_22820	COG1584	GPR1 FUN34 yaaH family protein
CRN74_22830	COG0484	heat shock protein binding
CRN74_22840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CRN74_22845	COG0583	DNA-binding transcription factor activity
CRN74_22860	COG0196	riboflavin kinase activity
CRN74_22865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CRN74_22875	COG1047	Peptidyl-prolyl cis-trans
CRN74_22880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CRN74_22890	COG0505	Belongs to the CarA family
CRN74_22895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CRN74_22900	COG1280	lysine exporter protein (LysE YggA)
CRN74_22905	COG2966	Psort location CytoplasmicMembrane, score
CRN74_22915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CRN74_22920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CRN74_22925	COG2967	ApaG domain
CRN74_22930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CRN74_22940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN74_22945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CRN74_22950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CRN74_22960	COG0564	pseudouridine synthase activity
CRN74_22995	COG2375	cellular response to nickel ion
CRN74_23005	COG0417	DNA replication proofreading
CRN74_23010	COG0586	Pfam SNARE associated Golgi protein
CRN74_23020	COG1178	ABC-type Fe3 transport system permease component
CRN74_23025	COG4143	(ABC) transporter
CRN74_23030	COG4533	DNA binding
CRN74_23035	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CRN74_23045	COG2814	Major facilitator Superfamily
CRN74_23050	COG0814	amino acid
CRN74_23055	COG3033	Beta-eliminating lyase
CRN74_23070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CRN74_23075	COG0473	3-isopropylmalate dehydrogenase activity
CRN74_23090	COG1022	Amp-dependent synthetase and ligase
CRN74_23095	COG0028	Belongs to the TPP enzyme family
CRN74_23105	COG1609	Transcriptional regulator
CRN74_23120	COG0275	rRNA processing
CRN74_23125	COG3116	cell division
CRN74_23130	COG0768	penicillin binding
CRN74_23135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CRN74_23140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity