locus-tag	class	description
FOC37_00005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC37_00010	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOC37_00015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOC37_00020	COG2105	PFAM AIG2 family protein
FOC37_00025	COG2911	Protein conserved in bacteria
FOC37_00030	COG0729	surface antigen
FOC37_00035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC37_00040	COG1253	flavin adenine dinucleotide binding
FOC37_00050	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOC37_00055	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOC37_00060	COG0737	Belongs to the 5'-nucleotidase family
FOC37_00070	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC37_00075	COG3061	Opacity-associated protein A
FOC37_00085	COG0359	binds to the 23S rRNA
FOC37_00090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC37_00095	COG2965	DNA replication, synthesis of RNA primer
FOC37_00100	COG0360	Binds together with S18 to 16S ribosomal RNA
FOC37_00115	COG1073	alpha beta
FOC37_00120	COG3650	response to hydrogen peroxide
FOC37_00125	COG1960	acyl-CoA dehydrogenase activity
FOC37_00130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC37_00135	COG0557	exoribonuclease II activity
FOC37_00140	COG1959	2 iron, 2 sulfur cluster binding
FOC37_00145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOC37_00150	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOC37_00155	COG0330	HflC and HflK could
FOC37_00160	COG0330	HflC and HflK could
FOC37_00165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC37_00175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC37_00180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOC37_00185	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC37_00190	COG0802	atpase or kinase
FOC37_00195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC37_00195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOC37_00200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC37_00220	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOC37_00225	COG1162	GTPase activity
FOC37_00230	COG0688	phosphatidylethanolamine metabolic process
FOC37_00235	COG3264	Mechanosensitive ion channel
FOC37_00235	COG1511	domain protein
FOC37_00240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOC37_00245	COG1053	succinate dehydrogenase
FOC37_00250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC37_00255	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOC37_00260	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOC37_00270	COG2076	Multidrug Resistance protein
FOC37_00295	COG0459	protein refolding
FOC37_00300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOC37_00315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC37_00325	COG4232	protein-disulfide reductase activity
FOC37_00330	COG3383	formate dehydrogenase (NAD+) activity
FOC37_00335	COG0493	'glutamate synthase
FOC37_00335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_00340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_00340	COG0493	'glutamate synthase
FOC37_00345	COG2271	Major facilitator Superfamily
FOC37_00350	COG2721	sulfolactate sulfo-lyase activity
FOC37_00355	COG3835	regulator
FOC37_00360	COG1929	Belongs to the glycerate kinase type-1 family
FOC37_00365	COG2084	Dehydrogenase
FOC37_00375	COG1309	transcriptional regulator
FOC37_00385	COG3876	Protein conserved in bacteria
FOC37_00395	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC37_00405	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOC37_00410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_00410	COG1263	PTS System
FOC37_00425	COG0840	transmembrane signaling receptor activity
FOC37_00430	COG1882	Formate acetyltransferase
FOC37_00435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC37_00440	COG0814	amino acid
FOC37_00450	COG0488	(ABC) transporter
FOC37_00465	COG3720	iron ion transport
FOC37_00470	COG4558	Periplasmic binding protein
FOC37_00475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_00480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOC37_00490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_00500	COG4774	siderophore transport
FOC37_00505	COG3264	Mechanosensitive ion channel
FOC37_00505	COG1511	domain protein
FOC37_00660	COG5002	protein histidine kinase activity
FOC37_00660	COG2205	protein histidine kinase activity
FOC37_00660	COG0784	Response regulator, receiver
FOC37_00670	COG1301	dicarboxylic acid transport
FOC37_00675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC37_00680	COG3162	membrane
FOC37_00685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC37_00725	COG0138	bifunctional purine biosynthesis protein purh
FOC37_00730	COG0151	Belongs to the GarS family
FOC37_00745	COG3068	Protein conserved in bacteria
FOC37_00750	COG1515	deoxyribonuclease V activity
FOC37_00755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC37_00760	COG2816	NAD+ diphosphatase activity
FOC37_00765	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FOC37_00770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOC37_00780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC37_00785	COG2104	thiamine diphosphate biosynthetic process
FOC37_00790	COG2022	thiamine diphosphate biosynthetic process
FOC37_00800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC37_00805	COG0085	RNA polymerase activity
FOC37_00810	COG0222	ribosome binding
FOC37_00815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOC37_00820	COG0081	regulation of translation
FOC37_00825	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC37_00830	COG0250	Participates in transcription elongation, termination and antitermination
FOC37_00835	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC37_00875	COG1072	(Pantothenic acid kinase))
FOC37_00880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOC37_00880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOC37_00920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC37_00925	COG1739	Uncharacterized protein family UPF0029
FOC37_00935	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC37_00935	COG1024	Enoyl-CoA hydratase
FOC37_00940	COG0183	Belongs to the thiolase family
FOC37_00950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOC37_00970	COG0805	protein transport
FOC37_00975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC37_00980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC37_00985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC37_00990	COG3165	ubiquinone biosynthetic process from chorismate
FOC37_00995	COG2226	methyltransferase
FOC37_01000	COG1322	Protein conserved in bacteria
FOC37_01005	COG0586	Pfam SNARE associated Golgi protein
FOC37_01010	COG1966	Carbon starvation protein
FOC37_01020	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOC37_01025	COG0412	Dienelactone hydrolase
FOC37_01030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOC37_01035	COG0583	DNA-binding transcription factor activity
FOC37_01045	COG0679	Auxin Efflux Carrier
FOC37_01050	COG0584	glycerophosphoryl diester phosphodiesterase
FOC37_01055	COG3842	ATPase activity
FOC37_01060	COG0395	ABC-type sugar transport system, permease component
FOC37_01065	COG1175	transmembrane transport
FOC37_01070	COG1653	transport
FOC37_01105	COG0410	ABC transporter
FOC37_01110	COG0411	ABC transporter
FOC37_01115	COG4177	L-phenylalanine transmembrane transporter activity
FOC37_01120	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC37_01125	COG0683	leucine binding
FOC37_01130	COG0456	acetyltransferase
FOC37_01140	COG2177	Part of the ABC transporter FtsEX involved in
FOC37_01145	COG2884	Cell division ATP-binding protein ftsE
FOC37_01150	COG0552	protein localization to endoplasmic reticulum
FOC37_01155	COG0742	ribosomal rna small subunit methyltransferase
FOC37_01160	COG3776	membrane
FOC37_01175	COG3714	YhhN family
FOC37_01180	COG2217	Heavy metal translocating P-type atpase
FOC37_01185	COG0425	Belongs to the sulfur carrier protein TusA family
FOC37_01190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOC37_01200	COG0247	lactate metabolic process
FOC37_01205	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC37_01210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC37_01220	COG2271	Major facilitator Superfamily
FOC37_01225	COG0584	glycerophosphoryl diester phosphodiesterase
FOC37_01230	COG0561	phosphatase activity
FOC37_01235	COG2267	carboxylic ester hydrolase activity
FOC37_01240	COG1280	lysine exporter protein (LysE YggA)
FOC37_01245	COG1280	lysine exporter protein (LysE YggA)
FOC37_01250	COG0514	ATP-dependent DNA helicase (RecQ)
FOC37_01255	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FOC37_01260	COG2050	protein possibly involved in aromatic compounds catabolism
FOC37_01270	COG0598	Magnesium transport protein CorA
FOC37_01280	COG5564	TIM-barrel signal transduction protein
FOC37_01285	COG5441	Belongs to the UPF0261 family
FOC37_01295	COG0210	DNA helicase
FOC37_01300	COG1011	Hydrolase
FOC37_01305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC37_01310	COG3159	Protein conserved in bacteria
FOC37_01315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOC37_01320	COG5567	small periplasmic lipoprotein
FOC37_01330	COG3072	Adenylate cyclase
FOC37_01335	COG0181	hydroxymethylbilane synthase activity
FOC37_01340	COG1587	Uroporphyrinogen-III synthase
FOC37_01345	COG2959	enzyme of heme biosynthesis
FOC37_01350	COG3071	HemY protein
FOC37_01375	COG1113	amino acid transport
FOC37_01390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC37_01395	COG2244	polysaccharide biosynthetic process
FOC37_01400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC37_01405	COG0456	acetyltransferase
FOC37_01410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC37_01415	COG1088	dTDP-glucose 4,6-dehydratase activity
FOC37_01420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC37_01425	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC37_01430	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC37_01435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC37_01440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC37_01445	COG3118	belongs to the thioredoxin family
FOC37_01455	COG0248	Ppx GppA phosphatase
FOC37_01470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC37_01480	COG3121	Chaperone
FOC37_01495	COG3121	Chaperone
FOC37_01550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC37_01555	COG0583	DNA-binding transcription factor activity
FOC37_01565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC37_01575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC37_01580	COG3978	acetolactate synthase activity
FOC37_01600	COG3085	chromosome segregation
FOC37_01605	COG0583	DNA-binding transcription factor activity
FOC37_01610	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_01615	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_01620	COG1129	ABC transporter
FOC37_01625	COG1879	ABC-type sugar transport system periplasmic component
FOC37_01670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC37_01680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC37_01695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_01705	COG0678	peroxiredoxin activity
FOC37_01705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC37_01710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_01755	COG1629	transport
FOC37_01760	COG0165	Argininosuccinate lyase
FOC37_01770	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOC37_01780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOC37_01790	COG0460	homoserine dehydrogenase
FOC37_01790	COG0527	aspartate kinase activity
FOC37_01795	COG0626	cystathionine gamma-synthase activity
FOC37_01800	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FOC37_01805	COG0254	rRNA binding
FOC37_01810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC37_01815	COG1609	Transcriptional regulator
FOC37_01820	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOC37_01825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOC37_01830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOC37_01835	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC37_01845	COG3074	FtsZ-dependent cytokinesis
FOC37_01850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC37_01855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC37_01860	COG1494	fructose-1,6-bisphosphatase
FOC37_01865	COG2814	Major facilitator Superfamily
FOC37_01885	COG3152	Membrane
FOC37_01900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOC37_01910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC37_01925	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FOC37_01940	COG3678	ATP-independent chaperone mediated protein folding
FOC37_01945	COG0745	RESPONSE REGULATOR receiver
FOC37_01950	COG2205	protein histidine kinase activity
FOC37_01955	COG2169	Transcriptional regulator
FOC37_01955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC37_01960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC37_01965	COG1045	serine acetyltransferase
FOC37_01970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC37_01975	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOC37_01980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC37_01985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC37_01990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC37_01995	COG4942	peptidase
FOC37_02000	COG2861	carbohydrate metabolic process
FOC37_02010	COG0156	8-amino-7-oxononanoate synthase activity
FOC37_02015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_02020	COG0859	PFAM glycosyl transferase family 9
FOC37_02025	COG0859	PFAM glycosyl transferase family 9
FOC37_02030	COG1519	Transferase
FOC37_02040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC37_02050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC37_02055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC37_02060	COG2003	Belongs to the UPF0758 family
FOC37_02065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC37_02070	COG0756	dUTP diphosphatase activity
FOC37_02075	COG1309	transcriptional regulator
FOC37_02080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOC37_02085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOC37_02090	COG1561	YicC-like family, N-terminal region
FOC37_02095	COG3645	SOS response
FOC37_02115	COG5001	Diguanylate cyclase
FOC37_02120	COG1024	Enoyl-CoA hydratase
FOC37_02125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_02135	COG2860	membrane
FOC37_02140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC37_02150	COG1758	RNA polymerase activity
FOC37_02155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC37_02160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC37_02165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC37_02170	COG0786	glutamate:sodium symporter activity
FOC37_02175	COG2233	PERMEase
FOC37_02180	COG2982	Protein involved in outer membrane biogenesis
FOC37_02200	COG3423	Transcriptional regulator
FOC37_02215	COG2204	response regulator
FOC37_02220	COG0456	acetyltransferase
FOC37_02225	COG1490	D-aminoacyl-tRNA deacylase activity
FOC37_02230	COG1295	ribonuclease BN
FOC37_02235	COG1011	Hydrolase
FOC37_02245	COG0174	glutamine synthetase
FOC37_02250	COG3852	Histidine kinase
FOC37_02260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC37_02270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOC37_02275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC37_02275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC37_02280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC37_02285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC37_02290	COG3084	Protein conserved in bacteria
FOC37_02300	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC37_02330	COG2186	Transcriptional regulator
FOC37_02335	COG0477	Major facilitator Superfamily
FOC37_02340	COG1609	Transcriptional regulator
FOC37_02345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_02350	COG1879	ABC-type sugar transport system periplasmic component
FOC37_02355	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_02365	COG1869	D-ribose catabolic process
FOC37_02370	COG3158	transport of potassium into the cell
FOC37_02375	COG0714	Associated with various cellular activities
FOC37_02380	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOC37_02390	COG2502	aspartate--ammonia ligase
FOC37_02395	COG1522	sequence-specific DNA binding
FOC37_02400	COG0716	FMN binding
FOC37_02405	COG0445	tRNA wobble uridine modification
FOC37_02410	COG0357	Ribosomal RNA small subunit methyltransferase G
FOC37_02415	COG3312	ion transport
FOC37_02420	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC37_02430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOC37_02435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC37_02440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOC37_02450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOC37_02455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOC37_02460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC37_02465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC37_02510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC37_02515	COG0573	inorganic phosphate transmembrane transporter activity
FOC37_02520	COG0581	inorganic phosphate transmembrane transporter activity
FOC37_02530	COG0704	Plays a role in the regulation of phosphate uptake
FOC37_02540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_02545	COG0765	amino acid transport
FOC37_02550	COG0765	amino acid transport
FOC37_02555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_02560	COG2252	PERMEase
FOC37_02575	COG4191	Histidine kinase
FOC37_02580	COG0431	NADPH-dependent FMN reductase
FOC37_02585	COG0840	transmembrane signaling receptor activity
FOC37_02590	COG2011	ABC-type metal ion transport system permease component
FOC37_02595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC37_02605	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOC37_02610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC37_02615	COG0706	membrane insertase activity
FOC37_02625	COG0594	ribonuclease P activity
FOC37_02630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC37_02640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC37_02645	COG0592	DNA-directed DNA polymerase activity
FOC37_02655	COG0187	DNA topoisomerase II activity
FOC37_02660	COG0561	phosphatase activity
FOC37_02665	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC37_02675	COG1940	carbohydrate kinase activity
FOC37_02680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_02690	COG2723	6-phospho-beta-galactosidase activity
FOC37_02695	COG2188	Transcriptional regulator
FOC37_02700	COG2423	ornithine cyclodeaminase activity
FOC37_02715	COG2186	Transcriptional regulator
FOC37_02720	COG3734	2-keto-3-deoxy-galactonokinase
FOC37_02725	COG0800	Aldolase
FOC37_02730	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_02735	COG2271	Major facilitator Superfamily
FOC37_02740	COG0823	Involved in the tonB-independent uptake of proteins
FOC37_02745	COG5645	(Lipo)protein
FOC37_02765	COG3977	Valine--pyruvate aminotransferase
FOC37_02770	COG0366	Alpha amylase catalytic
FOC37_02790	COG2885	chlorophyll binding
FOC37_02805	COG0456	acetyltransferase
FOC37_02810	COG2818	Glycosylase
FOC37_02820	COG0751	glycine-tRNA ligase activity
FOC37_02830	COG2213	PTS system mannitol-specific
FOC37_02830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_02835	COG0246	Mannitol dehydrogenase
FOC37_02840	COG3722	fumarate hydratase activity
FOC37_02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_02865	COG3077	Addiction module antitoxin, RelB DinJ family
FOC37_02870	COG2258	MOSC domain
FOC37_02875	COG0840	transmembrane signaling receptor activity
FOC37_02880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC37_02885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC37_02895	COG0437	4 iron, 4 sulfur cluster binding
FOC37_02900	COG2864	formate dehydrogenase
FOC37_02905	COG3058	Necessary for formate dehydrogenase activity
FOC37_02910	COG1921	L-seryl-tRNASec selenium transferase activity
FOC37_02915	COG3276	selenocysteine insertion sequence binding
FOC37_02925	COG3274	enterobacterial common antigen metabolic process
FOC37_02935	COG1335	isochorismatase
FOC37_02945	COG3188	usher protein
FOC37_02950	COG3121	Chaperone
FOC37_02960	COG1070	Carbohydrate kinase
FOC37_02965	COG2115	Belongs to the xylose isomerase family
FOC37_02970	COG4213	ABC transporter substrate-binding protein
FOC37_02980	COG4214	carbohydrate transport
FOC37_02985	COG1609	Transcriptional regulator
FOC37_02985	COG2207	Transcriptional regulator
FOC37_03000	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOC37_03005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_03025	COG3623	hexulose-6-phosphate isomerase
FOC37_03050	COG3121	Chaperone
FOC37_03055	COG3539	Fimbrial protein
FOC37_03065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOC37_03070	COG2986	histidine ammonia-lyase
FOC37_03090	COG1764	response to oxidative stress
FOC37_03095	COG2194	sulfuric ester hydrolase activity
FOC37_03100	COG2197	response regulator
FOC37_03105	COG3851	Histidine kinase
FOC37_03110	COG2271	Major facilitator Superfamily
FOC37_03120	COG0747	negative chemotaxis
FOC37_03125	COG0601	transmembrane transport
FOC37_03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC37_03135	COG0444	Belongs to the ABC transporter superfamily
FOC37_03140	COG4608	Belongs to the ABC transporter superfamily
FOC37_03145	COG2194	sulfuric ester hydrolase activity
FOC37_03165	COG1192	Involved in chromosome partitioning
FOC37_03175	COG1215	transferase activity, transferring glycosyl groups
FOC37_03180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC37_03185	COG3118	belongs to the thioredoxin family
FOC37_03185	COG0457	Tetratricopeptide repeat
FOC37_03190	COG2199	diguanylate cyclase activity
FOC37_03190	COG2200	EAL domain
FOC37_03200	COG3121	Chaperone
FOC37_03205	COG3188	usher protein
FOC37_03215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC37_03230	COG1301	dicarboxylic acid transport
FOC37_03235	COG0612	Peptidase, M16
FOC37_03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_03245	COG1942	4-Oxalocrotonate Tautomerase
FOC37_03250	COG2200	EAL domain
FOC37_03255	COG2982	Protein involved in outer membrane biogenesis
FOC37_03260	COG2134	cdp-diacylglycerol pyrophosphatase
FOC37_03265	COG1295	ribonuclease BN
FOC37_03280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_03285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOC37_03295	COG0742	ribosomal rna small subunit methyltransferase
FOC37_03300	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FOC37_03310	COG0589	response to stress
FOC37_03320	COG0306	phosphate transporter
FOC37_03325	COG2081	HI0933 family
FOC37_03340	COG0583	DNA-binding transcription factor activity
FOC37_03345	COG2814	Major facilitator Superfamily
FOC37_03360	COG3718	enzyme involved in inositol metabolism
FOC37_03375	COG3962	Belongs to the TPP enzyme family
FOC37_03380	COG0673	inositol 2-dehydrogenase activity
FOC37_03385	COG1082	Xylose isomerase domain protein TIM barrel
FOC37_03390	COG1247	-acetyltransferase
FOC37_03395	COG1741	Belongs to the pirin family
FOC37_03400	COG1609	Transcriptional regulator
FOC37_03405	COG2610	gluconate transmembrane transporter activity
FOC37_03410	COG3265	gluconokinase activity
FOC37_03415	COG2095	MarC family integral membrane protein
FOC37_03420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC37_03440	COG3275	phosphorelay sensor kinase activity
FOC37_03445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC37_03450	COG1523	belongs to the glycosyl hydrolase 13 family
FOC37_03455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC37_03460	COG0297	glycogen (starch) synthase activity
FOC37_03465	COG0058	SHG alpha-glucan phosphorylase activity
FOC37_03470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC37_03475	COG1349	DNA-binding transcription factor activity
FOC37_03480	COG0705	Rhomboid family
FOC37_03490	COG2909	trisaccharide binding
FOC37_03495	COG0058	SHG alpha-glucan phosphorylase activity
FOC37_03500	COG1640	4-alpha-glucanotransferase
FOC37_03505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC37_03505	COG0316	Belongs to the HesB IscA family
FOC37_03515	COG0596	Alpha beta hydrolase
FOC37_03535	COG1918	ferrous iron import across plasma membrane
FOC37_03540	COG2183	response to ionizing radiation
FOC37_03545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC37_03550	COG0745	RESPONSE REGULATOR receiver
FOC37_03570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC37_03575	COG1011	Hydrolase
FOC37_03585	COG0494	nUDIX hydrolase
FOC37_03590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC37_03615	COG4796	Type ii and iii secretion system protein
FOC37_03620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC37_03640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC37_03650	COG0180	Tryptophanyl-tRNA synthetase
FOC37_03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC37_03655	COG1648	precorrin-2 dehydrogenase activity
FOC37_03665	COG2146	nitrite reductase [NAD(P)H] activity
FOC37_03670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC37_03675	COG0402	S-adenosylhomocysteine deaminase activity
FOC37_03680	COG0738	Major facilitator superfamily
FOC37_03700	COG1486	melibiose metabolic process
FOC37_03705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC37_03710	COG0433	COG0433 Predicted ATPase
FOC37_03725	COG1289	transmembrane transporter activity
FOC37_03735	COG1765	OsmC-like protein
FOC37_03740	COG3954	Phosphoribulokinase
FOC37_03745	COG3089	Belongs to the UPF0270 family
FOC37_03750	COG0429	hydrolase of the alpha beta-hydrolase fold
FOC37_03765	COG4521	taurine ABC transporter
FOC37_03775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC37_03780	COG2175	clavaminate synthase activity
FOC37_03790	COG1216	Glycosyl transferase, family 2
FOC37_03795	COG0488	(ABC) transporter
FOC37_03800	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_03810	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOC37_03815	COG1047	Peptidyl-prolyl cis-trans
FOC37_03825	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC37_03830	COG2964	Protein conserved in bacteria
FOC37_03835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOC37_03840	COG2923	Belongs to the DsrF TusC family
FOC37_03845	COG2168	tRNA wobble position uridine thiolation
FOC37_03850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOC37_03855	COG0049	tRNA binding
FOC37_03865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC37_03880	COG0051	transcription antitermination factor activity, RNA binding
FOC37_03895	COG0089	rRNA binding
FOC37_03905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOC37_03915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOC37_03920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOC37_03925	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC37_03930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOC37_03935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOC37_03940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOC37_03950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC37_03955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOC37_03960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC37_03965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOC37_03970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC37_03975	COG1841	ribosomal large subunit assembly
FOC37_03980	COG0200	Binds to the 23S rRNA
FOC37_03985	COG0201	protein transport
FOC37_03990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC37_03995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC37_04000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOC37_04005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOC37_04015	COG0203	ribosomal protein L17
FOC37_04025	COG0789	Transcriptional regulator
FOC37_04030	COG3036	rescue of stalled ribosome
FOC37_04035	COG1970	mechanosensitive ion channel activity
FOC37_04040	COG0569	domain protein
FOC37_04045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC37_04045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC37_04050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC37_04055	COG0242	peptide deformylase activity
FOC37_04060	COG0758	DNA mediated transformation
FOC37_04070	COG0551	DNA topoisomerase type I activity
FOC37_04075	COG0009	L-threonylcarbamoyladenylate synthase
FOC37_04080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC37_04085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC37_04125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOC37_04130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC37_04135	COG2224	Isocitrate lyase
FOC37_04140	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FOC37_04145	COG0183	Belongs to the thiolase family
FOC37_04150	COG2031	fatty acid transporter
FOC37_04155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC37_04160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC37_04165	COG2204	response regulator
FOC37_04170	COG3852	Histidine kinase
FOC37_04175	COG1414	Transcriptional regulator
FOC37_04200	COG0527	aspartate kinase activity
FOC37_04210	COG3223	Belongs to the PsiE family
FOC37_04215	COG3833	ABC-type maltose transport systems, permease component
FOC37_04220	COG1175	transmembrane transport
FOC37_04240	COG4580	involved in the transport of maltose and maltodextrins
FOC37_04255	COG3161	chorismate lyase activity
FOC37_04265	COG2937	Belongs to the GPAT DAPAT family
FOC37_04270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC37_04275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOC37_04280	COG3237	CsbD-like
FOC37_04285	COG0735	belongs to the Fur family
FOC37_04295	COG2131	deaminase
FOC37_04340	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOC37_04345	COG5532	Uncharacterized conserved protein (DUF2303)
FOC37_04380	COG3645	SOS response
FOC37_04380	COG3646	Phage regulatory protein
FOC37_04385	COG1403	HNH endonuclease
FOC37_04565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC37_04575	COG0604	alcohol dehydrogenase
FOC37_04580	COG0305	Participates in initiation and elongation during chromosome replication
FOC37_04585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC37_04590	COG1448	Aminotransferase
FOC37_04595	COG2315	Protein conserved in bacteria
FOC37_04600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC37_04605	COG0629	single-stranded DNA binding
FOC37_04610	COG3550	peptidyl-serine autophosphorylation
FOC37_04625	COG2252	PERMEase
FOC37_04630	COG0025	NhaP-type Na H and K H
FOC37_04635	COG0583	DNA-binding transcription factor activity
FOC37_04640	COG1380	Effector of murein hydrolase LrgA
FOC37_04650	COG1126	abc transporter atp-binding protein
FOC37_04655	COG0765	amino acid transport
FOC37_04660	COG4597	amino acid ABC transporter
FOC37_04665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_04675	COG1560	Kdo2-lipid A biosynthetic process
FOC37_04685	COG1129	ABC transporter
FOC37_04690	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_04700	COG1069	ribulokinase activity
FOC37_04710	COG0471	metal ion transport
FOC37_04715	COG1278	Cold shock
FOC37_04720	COG1278	Cold shock
FOC37_04725	COG3133	Outer membrane lipoprotein
FOC37_04730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOC37_04735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC37_04740	COG2264	protein methyltransferase activity
FOC37_04745	COG4145	pantothenate transmembrane transporter activity
FOC37_04750	COG3924	membrane
FOC37_04755	COG0439	Biotin carboxylase
FOC37_04760	COG0511	ligase activity, forming carbon-carbon bonds
FOC37_04770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOC37_04780	COG0604	alcohol dehydrogenase
FOC37_04785	COG2199	diguanylate cyclase activity
FOC37_04785	COG2200	EAL domain
FOC37_04790	COG1077	Cell shape determining protein MreB Mrl
FOC37_04795	COG1792	Involved in formation and maintenance of cell shape
FOC37_04800	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOC37_04810	COG1530	ribonuclease E activity
FOC37_04815	COG3164	Protein of unknown function
FOC37_04820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC37_04825	COG0312	modulator of DNA gyrase
FOC37_04830	COG0583	DNA-binding transcription factor activity
FOC37_04840	COG1566	PFAM secretion protein HlyD family protein
FOC37_04845	COG1289	transmembrane transporter activity
FOC37_04850	COG1012	belongs to the aldehyde dehydrogenase family
FOC37_04860	COG2732	(Barnase) inhibitor
FOC37_04865	COG3028	Belongs to the UPF0307 family
FOC37_04870	COG0312	modulator of DNA gyrase
FOC37_04875	COG3783	Cytochrome b(562)
FOC37_04880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC37_04910	COG3964	amidohydrolase
FOC37_04925	COG3711	transcriptional antiterminator
FOC37_04925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_04930	COG3093	addiction module antidote protein HigA
FOC37_04940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC37_04950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_04950	COG1263	PTS System
FOC37_04955	COG0366	Alpha amylase catalytic
FOC37_04970	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOC37_04975	COG0540	Belongs to the ATCase OTCase family
FOC37_04980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_04985	COG2271	Major facilitator Superfamily
FOC37_04990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_04995	COG1660	Displays ATPase and GTPase activities
FOC37_05000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_05010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC37_05015	COG1137	ATPase activity
FOC37_05020	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOC37_05025	COG3117	lipopolysaccharide transmembrane transporter activity
FOC37_05030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOC37_05035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOC37_05035	COG0517	IMP dehydrogenase activity
FOC37_05040	COG0530	calcium, potassium:sodium antiporter activity
FOC37_05045	COG1127	ABC transporter
FOC37_05050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC37_05055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC37_05060	COG2854	intermembrane phospholipid transfer
FOC37_05065	COG3113	response to antibiotic
FOC37_05070	COG5007	Belongs to the BolA IbaG family
FOC37_05075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC37_05080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC37_05085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC37_05090	COG3105	Protein conserved in bacteria
FOC37_05095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOC37_05100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC37_05105	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOC37_05110	COG0625	glutathione transferase activity
FOC37_05115	COG2969	positive regulation of protein catabolic process
FOC37_05125	COG0493	'glutamate synthase
FOC37_05130	COG0067	glutamate synthase
FOC37_05130	COG0069	glutamate synthase activity
FOC37_05130	COG0070	glutamate synthase
FOC37_05135	COG1242	4 iron, 4 sulfur cluster binding
FOC37_05140	COG5002	protein histidine kinase activity
FOC37_05140	COG2198	Histidine kinase
FOC37_05140	COG0784	Response regulator, receiver
FOC37_05145	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FOC37_05150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC37_05155	COG2823	Periplasmic or secreted lipoprotein
FOC37_05160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC37_05165	COG0792	nuclease activity
FOC37_05175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC37_05190	COG1064	alcohol dehydrogenase
FOC37_05195	COG1741	Belongs to the pirin family
FOC37_05200	COG0583	DNA-binding transcription factor activity
FOC37_05205	COG0435	Glutathione S-transferase
FOC37_05210	COG2259	Doxx family
FOC37_05220	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FOC37_05225	COG4575	ribosome binding
FOC37_05240	COG0586	Pfam SNARE associated Golgi protein
FOC37_05255	COG2271	Major facilitator Superfamily
FOC37_05265	COG0246	Mannitol dehydrogenase
FOC37_05270	COG2721	sulfolactate sulfo-lyase activity
FOC37_05280	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOC37_05285	COG0861	Integral membrane protein TerC family
FOC37_05290	COG0673	inositol 2-dehydrogenase activity
FOC37_05295	COG1451	nucleotide metabolic process
FOC37_05300	COG3468	outer membrane autotransporter barrel domain protein
FOC37_05305	COG2813	Specifically methylates the guanine in position
FOC37_05310	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC37_05310	COG1902	pentaerythritol trinitrate reductase activity
FOC37_05320	COG2378	regulation of single-species biofilm formation
FOC37_05330	COG3247	response to pH
FOC37_05335	COG2814	Major facilitator Superfamily
FOC37_05365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC37_05370	COG0358	DNA primase activity
FOC37_05380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC37_05385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC37_05390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC37_05400	COG0617	tRNA 3'-terminal CCA addition
FOC37_05405	COG4991	sh3 domain protein
FOC37_05410	COG3025	triphosphatase activity
FOC37_05415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOC37_05420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC37_05420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOC37_05425	COG0531	amino acid
FOC37_05435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC37_05440	COG3384	dioxygenase
FOC37_05445	COG0754	glutathionylspermidine amidase activity
FOC37_05450	COG5463	Belongs to the UPF0441 family
FOC37_05455	COG1538	Outer membrane efflux protein
FOC37_05460	COG0494	nUDIX hydrolase
FOC37_05465	COG3151	Protein conserved in bacteria
FOC37_05470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC37_05475	COG3150	esterase
FOC37_05480	COG0187	DNA topoisomerase II activity
FOC37_05490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOC37_05495	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_05500	COG0745	RESPONSE REGULATOR receiver
FOC37_05505	COG2205	protein histidine kinase activity
FOC37_05510	COG1653	transport
FOC37_05515	COG0667	Aldo Keto reductase
FOC37_05520	COG0583	DNA-binding transcription factor activity
FOC37_05530	COG3716	PTS system mannose fructose sorbose family IID component
FOC37_05535	COG3715	PTS system
FOC37_05540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_05545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC37_05550	COG0204	Acyl-transferase
FOC37_05555	COG2132	Multicopper oxidase
FOC37_05575	COG0656	L-ascorbic acid biosynthetic process
FOC37_05580	COG1979	alcohol dehydrogenase
FOC37_05585	COG2207	Transcriptional regulator
FOC37_05590	COG0586	Pfam SNARE associated Golgi protein
FOC37_05595	COG0626	cystathionine gamma-synthase activity
FOC37_05600	COG0811	peptide transport
FOC37_05605	COG0848	biopolymer transport protein
FOC37_05650	COG4964	Belongs to the GSP D family
FOC37_05680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_05685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_05705	COG4774	siderophore transport
FOC37_05715	COG1120	ATPase activity
FOC37_05720	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_05725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_05730	COG4592	Periplasmic binding protein
FOC37_05735	COG0840	transmembrane signaling receptor activity
FOC37_05755	COG3133	Outer membrane lipoprotein
FOC37_05760	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FOC37_05765	COG0437	4 iron, 4 sulfur cluster binding
FOC37_05770	COG5557	Pfam Polysulphide reductase, NrfD
FOC37_05775	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FOC37_05780	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOC37_05785	COG1773	rubredoxin
FOC37_05790	COG0375	protein maturation
FOC37_05795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC37_05795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC37_05800	COG0298	carbon dioxide binding
FOC37_05805	COG0409	Hydrogenase expression formation protein
FOC37_05810	COG0309	Hydrogenase expression formation protein (HypE)
FOC37_05815	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC37_05820	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOC37_05825	COG5001	Diguanylate cyclase
FOC37_05835	COG4303	Ethanolamine ammonia lyase large subunit
FOC37_05840	COG4302	ethanolamine ammonia-lyase activity
FOC37_05845	COG0477	Major facilitator Superfamily
FOC37_05860	COG0745	RESPONSE REGULATOR receiver
FOC37_05860	COG3706	GGDEF domain
FOC37_05870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOC37_05875	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC37_05880	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC37_05885	COG4607	ABC-type enterochelin transport system periplasmic component
FOC37_05895	COG4605	iron ion homeostasis
FOC37_05900	COG4604	ABC transporter, ATP-binding protein
FOC37_05960	COG1289	transmembrane transporter activity
FOC37_05995	COG3121	Chaperone
FOC37_06000	COG3121	Chaperone
FOC37_06005	COG3188	usher protein
FOC37_06035	COG2040	homocysteine
FOC37_06040	COG0833	amino acid
FOC37_06045	COG1230	cation diffusion facilitator family transporter
FOC37_06080	COG3038	cytochrome b561
FOC37_06085	COG0789	Transcriptional regulator
FOC37_06095	COG0300	oxidoreductase activity
FOC37_06110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC37_06125	COG3447	MASE1 domain protein
FOC37_06125	COG5002	protein histidine kinase activity
FOC37_06125	COG5001	Diguanylate cyclase
FOC37_06130	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC37_06145	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FOC37_06150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_06150	COG2190	(PTS) system
FOC37_06150	COG1263	PTS System
FOC37_06170	COG2188	Transcriptional regulator
FOC37_06175	COG2771	luxR family
FOC37_06180	COG3916	Acyl-homoserine-lactone synthase
FOC37_06185	COG4810	utilization protein
FOC37_06190	COG4917	ethanolamine utilization protein
FOC37_06195	COG4766	ethanolamine catabolic process
FOC37_06210	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC37_06215	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FOC37_06225	COG4820	ethanolamine utilization protein (EutJ)
FOC37_06245	COG4303	Ethanolamine ammonia lyase large subunit
FOC37_06255	COG4816	utilization protein
FOC37_06270	COG2207	Transcriptional regulator
FOC37_06285	COG0305	Participates in initiation and elongation during chromosome replication
FOC37_06320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC37_06465	COG0789	Transcriptional regulator
FOC37_06480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC37_06550	COG2132	Multicopper oxidase
FOC37_06565	COG2205	protein histidine kinase activity
FOC37_06570	COG0745	RESPONSE REGULATOR receiver
FOC37_06575	COG1276	copper resistance
FOC37_06580	COG2372	response to copper ion
FOC37_06585	COG3667	copper resistance
FOC37_06590	COG2132	Multicopper oxidase
FOC37_06605	COG0739	heme binding
FOC37_06645	COG0745	RESPONSE REGULATOR receiver
FOC37_06660	COG2203	Gaf domain
FOC37_06660	COG3706	GGDEF domain
FOC37_06660	COG4251	negative regulation of phosphorylation
FOC37_06660	COG5001	Diguanylate cyclase
FOC37_06685	COG0431	NADPH-dependent FMN reductase
FOC37_06700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC37_06710	COG1982	Orn Lys Arg decarboxylase major
FOC37_06720	COG0741	lytic transglycosylase activity
FOC37_06730	COG1194	a g-specific adenine glycosylase
FOC37_06735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOC37_06740	COG3171	Protein conserved in bacteria
FOC37_06745	COG2066	Belongs to the glutaminase family
FOC37_06755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC37_06760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC37_06765	COG1872	DUF167
FOC37_06770	COG0762	integral membrane protein
FOC37_06775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC37_06780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC37_06785	COG2805	Type II/IV secretion system protein
FOC37_06795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC37_06800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOC37_06805	COG1678	Uncharacterized ACR, COG1678
FOC37_06810	COG0189	ligase activity
FOC37_06815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC37_06820	COG2356	endonuclease I
FOC37_06825	COG3091	SprT-like family
FOC37_06830	COG0640	Transcriptional regulator
FOC37_06840	COG2391	methyltransferase activity
FOC37_06845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC37_06850	COG1166	arginine decarboxylase activity
FOC37_06860	COG0501	Belongs to the peptidase M48B family
FOC37_06865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC37_06870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC37_06875	COG0126	phosphoglycerate kinase activity
FOC37_06880	COG0191	fructose-bisphosphate aldolase activity
FOC37_06890	COG1279	arginine transmembrane transporter activity
FOC37_06900	COG0583	DNA-binding transcription factor activity
FOC37_06905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC37_06910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC37_06915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC37_06925	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOC37_06930	COG3079	Belongs to the UPF0149 family
FOC37_06935	COG0006	proline dipeptidase activity
FOC37_06940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC37_06945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC37_06950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC37_06955	COG0509	glycine decarboxylation via glycine cleavage system
FOC37_06960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC37_06960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC37_06965	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_06975	COG1272	protein, Hemolysin III
FOC37_06980	COG0354	folic acid binding
FOC37_06985	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOC37_06995	COG0745	RESPONSE REGULATOR receiver
FOC37_07000	COG2205	protein histidine kinase activity
FOC37_07005	COG4452	Inner membrane protein CreD
FOC37_07010	COG0716	FMN binding
FOC37_07015	COG4974	Belongs to the 'phage' integrase family
FOC37_07020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC37_07025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC37_07055	COG3706	GGDEF domain
FOC37_07060	COG1522	sequence-specific DNA binding
FOC37_07075	COG2271	Major facilitator Superfamily
FOC37_07085	COG0484	heat shock protein binding
FOC37_07095	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_07100	COG1733	regulation of RNA biosynthetic process
FOC37_07105	COG0288	reversible hydration of carbon dioxide
FOC37_07125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC37_07135	COG2165	general secretion pathway protein
FOC37_07140	COG2165	general secretion pathway protein
FOC37_07200	COG0583	DNA-binding transcription factor activity
FOC37_07205	COG0583	DNA-binding transcription factor activity
FOC37_07210	COG0019	diaminopimelate decarboxylase activity
FOC37_07220	COG1609	Transcriptional regulator
FOC37_07230	COG0204	Acyl-transferase
FOC37_07230	COG0318	PFAM AMP-dependent synthetase and ligase
FOC37_07235	COG0477	Major facilitator Superfamily
FOC37_07240	COG0667	Aldo Keto reductase
FOC37_07245	COG0861	Integral membrane protein TerC family
FOC37_07250	COG3066	DNA modification
FOC37_07265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOC37_07275	COG2165	general secretion pathway protein
FOC37_07280	COG4795	General secretion pathway protein
FOC37_07295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOC37_07300	COG1025	Belongs to the peptidase M16 family
FOC37_07305	COG1074	ATP-dependent DNA helicase activity
FOC37_07310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC37_07315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOC37_07315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC37_07320	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC37_07340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOC37_07345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC37_07350	COG2166	iron-sulfur cluster assembly
FOC37_07355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC37_07365	COG0583	DNA-binding transcription factor activity
FOC37_07370	COG2363	Small membrane protein
FOC37_07375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOC37_07380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC37_07385	COG1611	Belongs to the LOG family
FOC37_07390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC37_07390	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC37_07400	COG3098	single-species biofilm formation
FOC37_07405	COG0564	pseudouridine synthase activity
FOC37_07420	COG2171	N-acyltransferase activity
FOC37_07425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOC37_07430	COG0024	Methionine aminopeptidase
FOC37_07435	COG0052	Belongs to the universal ribosomal protein uS2 family
FOC37_07440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOC37_07445	COG0528	UMP kinase activity
FOC37_07450	COG0233	cytoplasmic translational termination
FOC37_07455	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC37_07460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC37_07465	COG0575	Belongs to the CDS family
FOC37_07470	COG0750	zinc metalloprotease
FOC37_07480	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOC37_07490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC37_07495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_07500	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_07505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC37_07515	COG0825	malonyl-CoA metabolic process
FOC37_07525	COG0346	lactoylglutathione lyase activity
FOC37_07530	COG0037	tRNA processing
FOC37_07540	COG4568	rho-dependent transcription termination
FOC37_07550	COG4681	YaeQ
FOC37_07560	COG3015	lipoprotein NlpE involved in copper resistance
FOC37_07565	COG0442	prolyl-tRNA aminoacylation
FOC37_07570	COG1720	tRNA m6t6A37 methyltransferase activity
FOC37_07580	COG1464	Belongs to the NlpA lipoprotein family
FOC37_07585	COG2011	ABC-type metal ion transport system permease component
FOC37_07595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC37_07630	COG5544	Lipoprotein
FOC37_07635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC37_07640	COG1042	CoA-binding domain protein
FOC37_07640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_07640	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC37_07650	COG3118	belongs to the thioredoxin family
FOC37_07655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC37_07660	COG2814	Major facilitator Superfamily
FOC37_07665	COG1566	PFAM secretion protein HlyD family protein
FOC37_07675	COG1846	Transcriptional regulator
FOC37_07685	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOC37_07690	COG2814	Major facilitator Superfamily
FOC37_07700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC37_07715	COG0436	Aminotransferase
FOC37_07720	COG0582	viral genome integration into host DNA
FOC37_07735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC37_07835	COG1192	Involved in chromosome partitioning
FOC37_07865	COG0305	Participates in initiation and elongation during chromosome replication
FOC37_07930	COG3772	lysozyme
FOC37_08065	COG0235	Class ii aldolase
FOC37_08075	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC37_08085	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC37_08100	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
FOC37_08105	COG1960	acyl-CoA dehydrogenase activity
FOC37_08110	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC37_08115	COG0121	glutamine amidotransferase
FOC37_08120	COG3034	peptidoglycan biosynthetic process
FOC37_08125	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC37_08130	COG1805	sodium ion transport
FOC37_08135	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC37_08140	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC37_08145	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC37_08150	COG2871	sodium ion transport
FOC37_08155	COG1477	protein flavinylation
FOC37_08160	COG2991	Protein conserved in bacteria
FOC37_08170	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC37_08175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC37_08180	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC37_08200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC37_08205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC37_08210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_08215	COG2313	pseudouridylate synthase activity
FOC37_08220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_08230	COG3459	Glycosyltransferase 36 associated
FOC37_08245	COG2226	methyltransferase
FOC37_08260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC37_08265	COG3123	guanosine phosphorylase activity
FOC37_08270	COG2974	May be involved in recombination
FOC37_08275	COG1940	carbohydrate kinase activity
FOC37_08280	COG0419	ATPase involved in DNA repair
FOC37_08285	COG0420	3'-5' exonuclease activity
FOC37_08290	COG0745	RESPONSE REGULATOR receiver
FOC37_08295	COG5002	protein histidine kinase activity
FOC37_08305	COG1114	Component of the transport system for branched-chain amino acids
FOC37_08315	COG0366	Alpha amylase catalytic
FOC37_08330	COG0450	alkyl hydroperoxide reductase
FOC37_08335	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FOC37_08340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC37_08350	COG1862	Preprotein translocase
FOC37_08355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC37_08360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC37_08370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC37_08375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC37_08375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC37_08380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOC37_08390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOC37_08395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC37_08400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC37_08405	COG0142	geranyltranstransferase activity
FOC37_08415	COG0301	tRNA thio-modification
FOC37_08415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC37_08420	COG0693	protein deglycase activity
FOC37_08425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC37_08430	COG1666	GTP binding
FOC37_08435	COG2814	Major facilitator Superfamily
FOC37_08440	COG0109	protoheme IX farnesyltransferase activity
FOC37_08445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOC37_08450	COG1845	cytochrome c oxidase, subunit III
FOC37_08455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC37_08460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC37_08470	COG2223	nitrite transmembrane transporter activity
FOC37_08475	COG3056	Lipoprotein
FOC37_08480	COG0271	Belongs to the BolA IbaG family
FOC37_08495	COG0740	serine-type endopeptidase activity
FOC37_08500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC37_08505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC37_08510	COG0776	regulation of translation
FOC37_08515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC37_08520	COG1555	photosystem II stabilization
FOC37_08525	COG0824	Thioesterase
FOC37_08530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC37_08535	COG4533	DNA binding
FOC37_08540	COG0561	phosphatase activity
FOC37_08550	COG1522	sequence-specific DNA binding
FOC37_08555	COG1132	(ABC) transporter
FOC37_08560	COG1132	(ABC) transporter
FOC37_08565	COG0347	Belongs to the P(II) protein family
FOC37_08570	COG0004	ammonium transporteR
FOC37_08575	COG1946	Acyl-CoA thioesterase
FOC37_08580	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FOC37_08585	COG3695	enzyme binding
FOC37_08595	COG0582	viral genome integration into host DNA
FOC37_08655	COG1121	(ABC) transporter
FOC37_08660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_08665	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC37_08670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC37_08675	COG0254	rRNA binding
FOC37_08680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_08685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_08690	COG1309	transcriptional regulator
FOC37_08695	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOC37_08700	COG3264	Mechanosensitive ion channel
FOC37_08700	COG1196	nuclear chromosome segregation
FOC37_08715	COG2832	Protein of unknown function (DUF454)
FOC37_08720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC37_08730	COG0346	lactoylglutathione lyase activity
FOC37_08735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC37_08740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOC37_08745	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOC37_08750	COG0326	Molecular chaperone. Has ATPase activity
FOC37_08755	COG0563	adenylate kinase activity
FOC37_08760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOC37_08785	COG1216	Glycosyl transferase, family 2
FOC37_08785	COG1442	glycosyl transferase family 8
FOC37_08790	COG0463	Glycosyl transferase, family 2
FOC37_08800	COG0438	transferase activity, transferring glycosyl groups
FOC37_08825	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC37_08830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_08835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC37_08835	COG4651	solute:proton antiporter activity
FOC37_08840	COG2223	nitrite transmembrane transporter activity
FOC37_08845	COG0737	Belongs to the 5'-nucleotidase family
FOC37_08850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC37_08855	COG3735	TraB family
FOC37_08860	COG2217	Heavy metal translocating P-type atpase
FOC37_08865	COG0789	Transcriptional regulator
FOC37_08870	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC37_08875	COG0330	HflC and HflK could
FOC37_08880	COG3118	belongs to the thioredoxin family
FOC37_08885	COG0300	oxidoreductase activity
FOC37_08890	COG2755	lipolytic protein G-D-S-L family
FOC37_08895	COG4181	ATPase activity
FOC37_08900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOC37_08905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC37_08910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC37_08915	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_08920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC37_08925	COG0215	cysteine-tRNA ligase activity
FOC37_08930	COG2501	S4 domain
FOC37_08935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOC37_08945	COG0582	viral genome integration into host DNA
FOC37_09015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC37_09015	COG2169	Transcriptional regulator
FOC37_09020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC37_09030	COG2315	Protein conserved in bacteria
FOC37_09225	COG2246	polysaccharide biosynthetic process
FOC37_09260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC37_09265	COG1328	CTP reductase activity
FOC37_09275	COG2211	Major facilitator Superfamily
FOC37_09285	COG3423	Transcriptional regulator
FOC37_09360	COG4382	Mu-like prophage protein Gp16
FOC37_09415	COG4383	Mu-like prophage protein gp29
FOC37_09440	COG4397	Mu-like prophage major head subunit gpT
FOC37_09465	COG4386	tail sheath protein
FOC37_09530	COG1486	melibiose metabolic process
FOC37_09535	COG2169	Transcriptional regulator
FOC37_09545	COG3240	lipase activity
FOC37_09620	COG3122	Protein conserved in bacteria
FOC37_09660	COG0583	DNA-binding transcription factor activity
FOC37_09675	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOC37_09680	COG0583	DNA-binding transcription factor activity
FOC37_09685	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_09695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_09725	COG1902	pentaerythritol trinitrate reductase activity
FOC37_09735	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_09745	COG2610	gluconate transmembrane transporter activity
FOC37_09760	COG1940	carbohydrate kinase activity
FOC37_09765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC37_09770	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_09775	COG1129	ABC transporter
FOC37_09780	COG1879	ABC-type sugar transport system periplasmic component
FOC37_09785	COG1737	Transcriptional regulator
FOC37_09790	COG0698	ribose 5-phosphate isomerase
FOC37_09795	COG2850	peptidyl-arginine hydroxylation
FOC37_09800	COG5265	(ABC) transporter
FOC37_09815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC37_09825	COG2197	response regulator
FOC37_09830	COG1278	Cold shock
FOC37_09835	COG1278	Cold shock
FOC37_09840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC37_09845	COG3706	GGDEF domain
FOC37_09850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC37_09855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOC37_09860	COG0321	lipoyl(octanoyl) transferase activity
FOC37_09865	COG2921	Belongs to the UPF0250 family
FOC37_09870	COG1686	Belongs to the peptidase S11 family
FOC37_09875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOC37_09880	COG0772	Belongs to the SEDS family
FOC37_09885	COG0768	penicillin binding
FOC37_09895	COG0799	negative regulation of ribosome biogenesis
FOC37_09900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC37_09905	COG1466	dna polymerase III delta subunit
FOC37_09910	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FOC37_09915	COG0495	leucyl-tRNA aminoacylation
FOC37_09920	COG2888	peptidyl-tyrosine sulfation
FOC37_09930	COG1126	abc transporter atp-binding protein
FOC37_09935	COG0765	amino acid transport
FOC37_09940	COG0765	amino acid transport
FOC37_09955	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOC37_09960	COG4535	Mg2 and Co2 transporter CorC
FOC37_09965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOC37_09970	COG1702	phosphate starvation-inducible protein PhoH
FOC37_09975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC37_09980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC37_10015	COG0367	asparagine synthase
FOC37_10020	COG0647	UMP catabolic process
FOC37_10025	COG1940	carbohydrate kinase activity
FOC37_10025	COG1846	Transcriptional regulator
FOC37_10030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC37_10035	COG0363	glucosamine-6-phosphate deaminase activity
FOC37_10040	COG1263	PTS System
FOC37_10040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_10040	COG2190	(PTS) system
FOC37_10045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC37_10065	COG0735	belongs to the Fur family
FOC37_10075	COG0840	transmembrane signaling receptor activity
FOC37_10085	COG0596	Alpha beta hydrolase
FOC37_10090	COG2831	hemolysin activation secretion protein
FOC37_10095	COG3210	domain, Protein
FOC37_10175	COG3316	Transposase and inactivated derivatives
FOC37_10210	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOC37_10215	COG0033	Phosphoglucomutase
FOC37_10225	COG0745	RESPONSE REGULATOR receiver
FOC37_10230	COG2205	protein histidine kinase activity
FOC37_10235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOC37_10240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOC37_10260	COG3272	Protein of unknown function (DUF1722)
FOC37_10270	COG5212	phosphodiesterase
FOC37_10275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC37_10280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC37_10285	COG1984	allophanate hydrolase subunit 2
FOC37_10290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOC37_10315	COG2009	succinate dehydrogenase
FOC37_10320	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOC37_10325	COG1053	succinate dehydrogenase
FOC37_10335	COG0567	Dehydrogenase, E1 component
FOC37_10340	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC37_10345	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC37_10350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC37_10355	COG0737	Belongs to the 5'-nucleotidase family
FOC37_10360	COG1271	oxidase subunit
FOC37_10365	COG1294	oxidase, subunit
FOC37_10370	COG4890	Cyd operon protein YbgT
FOC37_10375	COG3790	cyd operon protein YbgE
FOC37_10380	COG0824	Thioesterase
FOC37_10385	COG0811	peptide transport
FOC37_10390	COG0848	biopolymer transport protein
FOC37_10395	COG3064	Membrane
FOC37_10395	COG3064	Membrane
FOC37_10400	COG0823	Involved in the tonB-independent uptake of proteins
FOC37_10405	COG2885	chlorophyll binding
FOC37_10410	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOC37_10440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC37_10450	COG1230	cation diffusion facilitator family transporter
FOC37_10455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_10455	COG2205	protein histidine kinase activity
FOC37_10460	COG2197	response regulator
FOC37_10465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC37_10470	COG0588	phosphoglycerate mutase activity
FOC37_10480	COG2017	converts alpha-aldose to the beta-anomer
FOC37_10485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC37_10495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC37_10505	COG1119	ATPase activity
FOC37_10510	COG3585	molybdate ion transport
FOC37_10510	COG2005	Transcriptional regulator
FOC37_10520	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC37_10525	COG4149	molybdate abc transporter
FOC37_10535	COG0561	phosphatase activity
FOC37_10540	COG2706	6-phosphogluconolactonase activity
FOC37_10550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC37_10560	COG2226	methyltransferase
FOC37_10565	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOC37_10575	COG0556	nucleotide-excision repair
FOC37_10580	COG4628	conserved protein (DUF2132)
FOC37_10585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC37_10590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC37_10595	COG0315	cyclic pyranopterin monophosphate synthase activity
FOC37_10600	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOC37_10605	COG0314	molybdopterin synthase activity
FOC37_10610	COG0670	Belongs to the BI1 family
FOC37_10615	COG0842	Transport permease protein
FOC37_10620	COG0842	Transport permease protein
FOC37_10625	COG1131	(ABC) transporter
FOC37_10630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_10635	COG1309	transcriptional regulator
FOC37_10640	COG0513	Belongs to the DEAD box helicase family
FOC37_10645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC37_10650	COG2239	Acts as a magnesium transporter
FOC37_10660	COG1686	Belongs to the peptidase S11 family
FOC37_10665	COG0277	FAD linked oxidase domain protein
FOC37_10675	COG1403	HNH endonuclease
FOC37_10685	COG2261	transglycosylase associated protein
FOC37_10695	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOC37_10710	COG4807	Protein conserved in bacteria
FOC37_10730	COG0411	ABC transporter
FOC37_10740	COG2897	thiosulfate sulfurtransferase activity
FOC37_10745	COG0673	inositol 2-dehydrogenase activity
FOC37_10755	COG1732	Glycine betaine
FOC37_10760	COG1174	glycine betaine transport
FOC37_10765	COG1125	glycine betaine transport
FOC37_10770	COG1174	glycine betaine transport
FOC37_10785	COG0583	DNA-binding transcription factor activity
FOC37_10795	COG0697	spore germination
FOC37_10815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC37_10820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC37_10825	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOC37_10830	COG1126	abc transporter atp-binding protein
FOC37_10835	COG0765	amino acid transport
FOC37_10840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_10845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC37_10855	COG4106	trans-aconitate 2-methyltransferase activity
FOC37_10870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC37_10890	COG0488	(ABC) transporter
FOC37_10895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC37_10900	COG0303	'Molybdopterin
FOC37_10910	COG0477	Major facilitator Superfamily
FOC37_10920	COG1136	(ABC) transporter
FOC37_10950	COG0583	DNA-binding transcription factor activity
FOC37_10955	COG0477	Major facilitator Superfamily
FOC37_10960	COG0302	gtp cyclohydrolase
FOC37_10965	COG2311	Membrane
FOC37_10970	COG1609	Transcriptional regulator
FOC37_10990	COG2116	formate transmembrane transporter activity
FOC37_10995	COG3604	Transcriptional regulator
FOC37_11000	COG3383	formate dehydrogenase (NAD+) activity
FOC37_11005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_11010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOC37_11020	COG3260	NADH ubiquinone oxidoreductase 20
FOC37_11025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_11030	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FOC37_11030	COG3261	NADH dehydrogenase
FOC37_11035	COG0651	ATP synthesis coupled electron transport
FOC37_11040	COG4237	Hydrogenase 4 membrane
FOC37_11045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC37_11050	COG0650	Formate hydrogenlyase subunit 4
FOC37_11055	COG0651	ATP synthesis coupled electron transport
FOC37_11060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_11065	COG0375	protein maturation
FOC37_11070	COG0298	carbon dioxide binding
FOC37_11075	COG2949	membrane
FOC37_11080	COG0281	malic enzyme
FOC37_11090	COG1346	cytolysis
FOC37_11095	COG1380	Effector of murein hydrolase LrgA
FOC37_11100	COG2814	Major facilitator Superfamily
FOC37_11120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC37_11120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC37_11125	COG0489	protein tyrosine kinase activity
FOC37_11130	COG0572	uridine kinase
FOC37_11140	COG2982	Protein involved in outer membrane biogenesis
FOC37_11145	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC37_11150	COG1253	flavin adenine dinucleotide binding
FOC37_11155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC37_11160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC37_11165	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC37_11170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOC37_11170	COG0140	phosphoribosyl-ATP diphosphatase activity
FOC37_11175	COG0107	imidazoleglycerol-phosphate synthase activity
FOC37_11185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOC37_11190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC37_11190	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC37_11195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC37_11205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOC37_11215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_11220	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_11225	COG1129	ABC transporter
FOC37_11230	COG0371	Dehydrogenase
FOC37_11240	COG0531	amino acid
FOC37_11245	COG2925	Exonuclease
FOC37_11270	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_11275	COG1129	ABC transporter
FOC37_11280	COG1879	ABC-type sugar transport system periplasmic component
FOC37_11290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC37_11300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC37_11310	COG4810	utilization protein
FOC37_11320	COG4656	Part of a membrane complex involved in electron transport
FOC37_11335	COG2096	Adenosyltransferase
FOC37_11360	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC37_11395	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC37_11415	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOC37_11425	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FOC37_11430	COG2241	protein methyltransferase activity
FOC37_11440	COG2875	Belongs to the precorrin methyltransferase family
FOC37_11490	COG1492	cobalamin metabolic process
FOC37_11510	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOC37_11515	COG0583	DNA-binding transcription factor activity
FOC37_11525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOC37_11530	COG2211	Major facilitator Superfamily
FOC37_11535	COG0137	argininosuccinate synthase activity
FOC37_11540	COG0534	Mate efflux family protein
FOC37_11545	COG0835	chemotaxis
FOC37_11545	COG0784	Response regulator, receiver
FOC37_11565	COG0561	phosphatase activity
FOC37_11570	COG1349	DNA-binding transcription factor activity
FOC37_11580	COG0583	DNA-binding transcription factor activity
FOC37_11605	COG2885	chlorophyll binding
FOC37_11605	COG3047	cAMP biosynthetic process
FOC37_11635	COG0791	NLP P60 protein
FOC37_11635	COG1388	LysM domain
FOC37_11700	COG3121	Chaperone
FOC37_11725	COG2205	protein histidine kinase activity
FOC37_11725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_11740	COG3842	ATPase activity
FOC37_11750	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC37_11755	COG2271	Major facilitator Superfamily
FOC37_11770	COG4565	transcriptional regulatory protein
FOC37_11775	COG3290	protein histidine kinase activity
FOC37_11780	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FOC37_11785	COG3052	prosthetic group binding
FOC37_11790	COG2301	Belongs to the HpcH HpaI aldolase family
FOC37_11795	COG3051	citrate lyase alpha subunit
FOC37_11810	COG0471	metal ion transport
FOC37_11825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC37_11835	COG2814	Major facilitator Superfamily
FOC37_11845	COG2211	Major facilitator Superfamily
FOC37_11860	COG2204	response regulator
FOC37_11895	COG0251	oxidation-reduction process
FOC37_11910	COG3228	Belongs to the MtfA family
FOC37_11930	COG3121	Chaperone
FOC37_11945	COG3121	Chaperone
FOC37_11950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC37_11980	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_11980	COG3321	synthase
FOC37_11980	COG0604	alcohol dehydrogenase
FOC37_11985	COG3250	beta-galactosidase activity
FOC37_11990	COG1609	Transcriptional regulator
FOC37_11995	COG1278	Cold shock
FOC37_12005	COG0840	transmembrane signaling receptor activity
FOC37_12010	COG1285	pathogenesis
FOC37_12020	COG2130	NADP-dependent
FOC37_12025	COG0589	response to stress
FOC37_12050	COG0643	Histidine kinase
FOC37_12050	COG2198	Histidine kinase
FOC37_12055	COG0835	chemotaxis
FOC37_12060	COG0840	transmembrane signaling receptor activity
FOC37_12065	COG0840	transmembrane signaling receptor activity
FOC37_12070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC37_12080	COG0745	RESPONSE REGULATOR receiver
FOC37_12085	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOC37_12090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC37_12095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC37_12110	COG3418	PFAM FlgN family protein
FOC37_12115	COG2747	anti-sigma28 factor FlgM
FOC37_12125	COG1815	bacterial-type flagellum-dependent cell motility
FOC37_12130	COG1558	bacterial-type flagellum-dependent cell motility
FOC37_12135	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOC37_12140	COG1749	Flagellar hook protein flgE
FOC37_12150	COG4786	Flagellar basal body rod
FOC37_12170	COG1256	bacterial-type flagellum assembly
FOC37_12175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC37_12220	COG2882	bacterial-type flagellum organization
FOC37_12230	COG1317	bacterial-type flagellum organization
FOC37_12235	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC37_12245	COG1677	Flagellar hook-basal body complex protein FliE
FOC37_12250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC37_12255	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOC37_12285	COG1191	sigma factor activity
FOC37_12295	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC37_12325	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC37_12325	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC37_12325	COG0506	proline dehydrogenase activity
FOC37_12330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC37_12370	COG1113	amino acid transport
FOC37_12380	COG2203	Gaf domain
FOC37_12380	COG2199	diguanylate cyclase activity
FOC37_12400	COG0366	Alpha amylase catalytic
FOC37_12405	COG0840	transmembrane signaling receptor activity
FOC37_12415	COG3136	membrane protein required for alginate biosynthesis
FOC37_12425	COG2197	response regulator
FOC37_12430	COG0322	excinuclease ABC activity
FOC37_12435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC37_12535	COG3121	Chaperone
FOC37_12540	COG3188	usher protein
FOC37_12555	COG2197	response regulator
FOC37_12575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_12580	COG0561	phosphatase activity
FOC37_12585	COG2223	nitrite transmembrane transporter activity
FOC37_12595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_12605	COG2197	response regulator
FOC37_12610	COG2223	nitrite transmembrane transporter activity
FOC37_12615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC37_12620	COG1140	nitrate reductase beta subunit
FOC37_12625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC37_12630	COG2181	nitrate reductase activity
FOC37_12640	COG3493	citrate carrier protein
FOC37_12645	COG4565	transcriptional regulatory protein
FOC37_12650	COG3290	protein histidine kinase activity
FOC37_12655	COG1349	DNA-binding transcription factor activity
FOC37_12660	COG2084	Dehydrogenase
FOC37_12665	COG3395	kinase activity
FOC37_12670	COG0235	Class ii aldolase
FOC37_12675	COG3622	Belongs to the hyi family
FOC37_12685	COG1609	Transcriptional regulator
FOC37_12690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_12695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_12700	COG2723	6-phospho-beta-galactosidase activity
FOC37_12705	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC37_12715	COG0672	)-iron permease
FOC37_12730	COG0577	efflux transmembrane transporter activity
FOC37_12730	COG1136	(ABC) transporter
FOC37_12740	COG1136	(ABC) transporter
FOC37_12740	COG0577	efflux transmembrane transporter activity
FOC37_12765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC37_12770	COG0006	proline dipeptidase activity
FOC37_12775	COG0457	Tetratricopeptide repeat
FOC37_12780	COG0726	polysaccharide deacetylase
FOC37_12780	COG1649	PFAM Uncharacterised BCR, COG1649
FOC37_12785	COG1215	transferase activity, transferring glycosyl groups
FOC37_12790	COG3658	cytochrome
FOC37_12800	COG1702	phosphate starvation-inducible protein PhoH
FOC37_12805	COG0387	Pfam Sodium calcium exchanger
FOC37_12815	COG2814	Major facilitator Superfamily
FOC37_12820	COG0583	DNA-binding transcription factor activity
FOC37_12825	COG3850	Histidine kinase
FOC37_12835	COG1294	oxidase, subunit
FOC37_12840	COG1271	oxidase subunit
FOC37_12845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_12855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC37_12860	COG3138	arginine N-succinyltransferase
FOC37_12870	COG3724	N-succinylarginine dihydrolase activity
FOC37_12890	COG1228	amidohydrolase
FOC37_12900	COG0402	S-adenosylhomocysteine deaminase activity
FOC37_12915	COG1129	ABC transporter
FOC37_12920	COG4211	Belongs to the binding-protein-dependent transport system permease family
FOC37_12925	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC37_12935	COG4942	peptidase
FOC37_12945	COG0012	GTP binding
FOC37_12955	COG0193	aminoacyl-tRNA hydrolase activity
FOC37_12965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC37_12975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOC37_12980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOC37_12985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC37_12990	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC37_12995	COG3094	Invasion gene expression up-regulator, SirB
FOC37_13000	COG2912	Transglutaminase-like superfamily
FOC37_13010	COG0659	secondary active sulfate transmembrane transporter activity
FOC37_13015	COG3706	GGDEF domain
FOC37_13035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC37_13045	COG3381	protein complex oligomerization
FOC37_13055	COG0477	Major facilitator Superfamily
FOC37_13060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_13070	COG0673	inositol 2-dehydrogenase activity
FOC37_13100	COG3102	Protein conserved in bacteria
FOC37_13105	COG3142	Participates in the control of copper homeostasis
FOC37_13120	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FOC37_13125	COG1801	Protein of unknown function DUF72
FOC37_13130	COG1335	isochorismatase
FOC37_13135	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOC37_13140	COG0494	nUDIX hydrolase
FOC37_13145	COG0217	transcriptional regulatory protein
FOC37_13155	COG0632	four-way junction helicase activity
FOC37_13160	COG2255	four-way junction helicase activity
FOC37_13165	COG3104	oligopeptide transport
FOC37_13170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_13175	COG1121	(ABC) transporter
FOC37_13180	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOC37_13185	COG0739	heme binding
FOC37_13190	COG1560	Kdo2-lipid A biosynthetic process
FOC37_13195	COG0469	pyruvate kinase activity
FOC37_13205	COG1737	Transcriptional regulator
FOC37_13210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC37_13215	COG0800	Aldolase
FOC37_13220	COG2076	Multidrug Resistance protein
FOC37_13225	COG2076	Multidrug Resistance protein
FOC37_13230	COG0251	oxidation-reduction process
FOC37_13235	COG1199	ATP-dependent helicase activity
FOC37_13245	COG3065	identical protein binding
FOC37_13250	COG0318	PFAM AMP-dependent synthetase and ligase
FOC37_13255	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOC37_13260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOC37_13265	COG2894	cell division
FOC37_13270	COG0850	regulation of cytokinetic process
FOC37_13280	COG3100	YcgL domain-containing protein
FOC37_13285	COG2951	lytic endotransglycosylase activity
FOC37_13290	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC37_13295	COG2983	Belongs to the UPF0260 family
FOC37_13325	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_13330	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC37_13335	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC37_13340	COG2186	Transcriptional regulator
FOC37_13345	COG2719	SpoVR family
FOC37_13350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC37_13355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC37_13360	COG2814	Major facilitator Superfamily
FOC37_13365	COG2199	diguanylate cyclase activity
FOC37_13365	COG2200	EAL domain
FOC37_13365	COG2202	Pas domain
FOC37_13375	COG2718	Belongs to the UPF0229 family
FOC37_13380	COG2766	serine protein kinase
FOC37_13385	COG3713	MltA-interacting MipA family protein
FOC37_13405	COG3139	Protein of unknown function (DUF1315)
FOC37_13410	COG1335	isochorismatase
FOC37_13415	COG0252	asparaginase activity
FOC37_13420	COG0616	signal peptide processing
FOC37_13425	COG0778	Nitroreductase
FOC37_13435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC37_13445	COG0494	nUDIX hydrolase
FOC37_13450	COG0708	Exodeoxyribonuclease III
FOC37_13455	COG0583	DNA-binding transcription factor activity
FOC37_13490	COG0788	formyltetrahydrofolate deformylase activity
FOC37_13495	COG3012	SEC-C Motif Domain Protein
FOC37_13500	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC37_13505	COG0745	RESPONSE REGULATOR receiver
FOC37_13515	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOC37_13520	COG1435	thymidine kinase activity
FOC37_13525	COG1012	belongs to the aldehyde dehydrogenase family
FOC37_13525	COG1454	alcohol dehydrogenase
FOC37_13530	COG2095	MarC family integral membrane protein
FOC37_13535	COG4166	transmembrane transport
FOC37_13550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC37_13555	COG0444	Belongs to the ABC transporter superfamily
FOC37_13565	COG3099	Belongs to the UPF0263 family
FOC37_13570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC37_13595	COG2350	Protein conserved in bacteria
FOC37_13600	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOC37_13605	COG1607	acyl-coa hydrolase
FOC37_13610	COG2917	probably involved in intracellular septation
FOC37_13630	COG3047	cAMP biosynthetic process
FOC37_13640	COG0159	tryptophan synthase activity
FOC37_13645	COG0133	tryptophan synthase activity
FOC37_13650	COG0135	phosphoribosylanthranilate isomerase activity
FOC37_13650	COG0134	indole-3-glycerol-phosphate synthase activity
FOC37_13660	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC37_13675	COG0613	PHP domain protein
FOC37_13680	COG0009	L-threonylcarbamoyladenylate synthase
FOC37_13685	COG1187	pseudouridine synthase activity
FOC37_13695	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_13700	COG0616	signal peptide processing
FOC37_13710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC37_13715	COG0583	DNA-binding transcription factor activity
FOC37_13725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC37_13730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC37_13735	COG0671	phosphoesterase, PA-phosphatase related
FOC37_13740	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FOC37_13745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOC37_13765	COG0023	Translation Initiation Factor
FOC37_13775	COG0235	Class ii aldolase
FOC37_13785	COG1349	DNA-binding transcription factor activity
FOC37_13790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC37_13795	COG2879	small protein
FOC37_13800	COG1966	Carbon starvation protein
FOC37_13805	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FOC37_13810	COG0243	molybdopterin cofactor binding
FOC37_13815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC37_13825	COG4659	FMN binding
FOC37_13830	COG4658	electron transport chain
FOC37_13835	COG3708	Transcriptional regulator
FOC37_13835	COG2207	Transcriptional regulator
FOC37_13840	COG4656	Part of a membrane complex involved in electron transport
FOC37_13850	COG4657	Part of a membrane complex involved in electron transport
FOC37_13860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOC37_13865	COG2274	protein secretion by the type I secretion system
FOC37_13885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC37_13900	COG1879	ABC-type sugar transport system periplasmic component
FOC37_13910	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_13920	COG0673	inositol 2-dehydrogenase activity
FOC37_13925	COG0385	Bile acid
FOC37_13930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOC37_13935	COG2190	(PTS) system
FOC37_13935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_13935	COG1263	PTS System
FOC37_13940	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_13950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC37_13955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_13955	COG1263	PTS System
FOC37_13960	COG1609	Transcriptional regulator
FOC37_13975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC37_13990	COG1136	(ABC) transporter
FOC37_14005	COG1309	transcriptional regulator
FOC37_14015	COG5339	Protein conserved in bacteria
FOC37_14025	COG0114	fumarate hydratase activity
FOC37_14045	COG2814	Major facilitator Superfamily
FOC37_14050	COG0583	DNA-binding transcription factor activity
FOC37_14055	COG1940	carbohydrate kinase activity
FOC37_14060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOC37_14080	COG1742	UPF0060 membrane protein
FOC37_14090	COG4221	oxidoreductase activity
FOC37_14100	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC37_14125	COG1393	Belongs to the ArsC family
FOC37_14130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC37_14155	COG0625	glutathione transferase activity
FOC37_14160	COG3604	Transcriptional regulator
FOC37_14165	COG0426	domain, Protein
FOC37_14165	COG1773	rubredoxin
FOC37_14170	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC37_14180	COG1522	sequence-specific DNA binding
FOC37_14190	COG4215	(ABC) transporter
FOC37_14205	COG1477	protein flavinylation
FOC37_14210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC37_14220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC37_14250	COG0028	Belongs to the TPP enzyme family
FOC37_14255	COG0440	acetolactate synthase activity
FOC37_14260	COG0251	oxidation-reduction process
FOC37_14265	COG1011	Hydrolase
FOC37_14275	COG0583	DNA-binding transcription factor activity
FOC37_14290	COG0738	Major facilitator superfamily
FOC37_14295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_14305	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_14315	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOC37_14330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC37_14335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC37_14340	COG0589	response to stress
FOC37_14345	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOC37_14350	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOC37_14365	COG0531	amino acid
FOC37_14375	COG0745	RESPONSE REGULATOR receiver
FOC37_14380	COG2205	protein histidine kinase activity
FOC37_14385	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC37_14395	COG3591	Belongs to the peptidase S1B family
FOC37_14410	COG1643	Atp-dependent helicase
FOC37_14415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC37_14420	COG3784	Protein of unknown function (DUF1318)
FOC37_14430	COG2911	Protein conserved in bacteria
FOC37_14435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC37_14440	COG3042	response to heat
FOC37_14445	COG1285	pathogenesis
FOC37_14455	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC37_14455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_14455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC37_14455	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC37_14460	COG0037	tRNA processing
FOC37_14465	COG0598	Magnesium transport protein CorA
FOC37_14470	COG4166	transmembrane transport
FOC37_14475	COG2866	Carboxypeptidase
FOC37_14480	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_14485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC37_14505	COG3768	UPF0283 membrane protein
FOC37_14510	COG3106	COG3106 Predicted ATPase
FOC37_14520	COG1983	PspC domain protein
FOC37_14530	COG1842	Phage shock protein A
FOC37_14535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC37_14550	COG4166	transmembrane transport
FOC37_14555	COG4168	peptide transport system, permease
FOC37_14560	COG4171	peptide transport system, permease
FOC37_14570	COG4172	Belongs to the ABC transporter superfamily
FOC37_14575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC37_14575	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC37_14580	COG0583	DNA-binding transcription factor activity
FOC37_14585	COG3104	oligopeptide transport
FOC37_14605	COG0625	glutathione transferase activity
FOC37_14615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC37_14625	COG3895	Periplasmic Protein
FOC37_14630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOC37_14635	COG3133	Outer membrane lipoprotein
FOC37_14640	COG1846	Transcriptional regulator
FOC37_14650	COG1566	PFAM secretion protein HlyD family protein
FOC37_14655	COG1289	transmembrane transporter activity
FOC37_14660	COG4989	oxidoreductase activity
FOC37_14665	COG3313	Fe-S protein
FOC37_14670	COG2194	sulfuric ester hydrolase activity
FOC37_14675	COG1309	transcriptional regulator
FOC37_14680	COG1902	pentaerythritol trinitrate reductase activity
FOC37_14685	COG0346	lactoylglutathione lyase activity
FOC37_14690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC37_14695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOC37_14700	COG0791	NLP P60 protein
FOC37_14705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC37_14715	COG1609	Transcriptional regulator
FOC37_14720	COG0583	DNA-binding transcription factor activity
FOC37_14725	COG2814	Major facilitator Superfamily
FOC37_14730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC37_14735	COG0307	riboflavin synthase, alpha
FOC37_14740	COG0534	Mate efflux family protein
FOC37_14770	COG4238	major outer membrane lipoprotein
FOC37_14775	COG1388	LysM domain
FOC37_14775	COG1376	ErfK ybiS ycfS ynhG family protein
FOC37_14780	COG2166	iron-sulfur cluster assembly
FOC37_14790	COG0719	Fe-S assembly protein
FOC37_14795	COG0396	ATPase activity
FOC37_14800	COG0719	Fe-S assembly protein
FOC37_14805	COG0316	Belongs to the HesB IscA family
FOC37_14810	COG2050	protein possibly involved in aromatic compounds catabolism
FOC37_14815	COG0277	FAD linked oxidase domain protein
FOC37_14815	COG0247	lactate metabolic process
FOC37_14820	COG0628	permease
FOC37_14830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC37_14830	COG0574	Belongs to the PEP-utilizing enzyme family
FOC37_14835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOC37_14840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC37_14855	COG3720	iron ion transport
FOC37_14860	COG4558	Periplasmic binding protein
FOC37_14870	COG0095	Lipoate-protein ligase
FOC37_14875	COG0791	NLP P60 protein
FOC37_14880	COG2076	Multidrug Resistance protein
FOC37_14885	COG2076	Multidrug Resistance protein
FOC37_14890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOC37_14895	COG0726	polysaccharide deacetylase
FOC37_14905	COG0463	Glycosyl transferase, family 2
FOC37_14910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC37_14915	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FOC37_14920	COG0386	Belongs to the glutathione peroxidase family
FOC37_14925	COG4139	cobalamin transport
FOC37_14935	COG0776	regulation of translation
FOC37_14955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOC37_14960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC37_14970	COG4249	Peptidase C14 caspase catalytic subunit p20
FOC37_14975	COG1811	Na channel or pump
FOC37_14980	COG1414	Transcriptional regulator
FOC37_14985	COG1129	ABC transporter
FOC37_14990	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_15010	COG1070	Carbohydrate kinase
FOC37_15015	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOC37_15020	COG3623	hexulose-6-phosphate isomerase
FOC37_15050	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC37_15055	COG1121	(ABC) transporter
FOC37_15060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_15065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_15075	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC37_15075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC37_15080	COG1703	isobutyryl-CoA mutase activity
FOC37_15085	COG1024	Enoyl-CoA hydratase
FOC37_15090	COG0427	acetyl-CoA hydrolase
FOC37_15095	COG0583	DNA-binding transcription factor activity
FOC37_15105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_15110	COG1917	Cupin 2, conserved barrel domain protein
FOC37_15120	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_15130	COG1175	transmembrane transport
FOC37_15135	COG0395	ABC-type sugar transport system, permease component
FOC37_15140	COG3842	ATPase activity
FOC37_15150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC37_15155	COG1988	membrane-bound metal-dependent
FOC37_15165	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC37_15175	COG0823	Involved in the tonB-independent uptake of proteins
FOC37_15180	COG2814	Major facilitator Superfamily
FOC37_15185	COG0501	Belongs to the peptidase M48B family
FOC37_15190	COG0793	Belongs to the peptidase S41A family
FOC37_15200	COG1956	GAF domain-containing protein
FOC37_15205	COG2995	paraquat-inducible protein a
FOC37_15210	COG3008	intermembrane lipid transfer
FOC37_15225	COG2203	Gaf domain
FOC37_15225	COG3706	GGDEF domain
FOC37_15225	COG4251	negative regulation of phosphorylation
FOC37_15225	COG5001	Diguanylate cyclase
FOC37_15255	COG0625	glutathione transferase activity
FOC37_15275	COG0697	spore germination
FOC37_15285	COG1187	pseudouridine synthase activity
FOC37_15290	COG0668	transmembrane transport
FOC37_15300	COG0589	response to stress
FOC37_15315	COG1276	copper resistance
FOC37_15320	COG2372	response to copper ion
FOC37_15325	COG1528	Iron-storage protein
FOC37_15340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC37_15345	COG1770	oligopeptidase
FOC37_15360	COG3141	response to X-ray
FOC37_15365	COG0513	Belongs to the DEAD box helicase family
FOC37_15370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOC37_15375	COG3140	Belongs to the UPF0181 family
FOC37_15385	COG0494	nUDIX hydrolase
FOC37_15390	COG1760	l-serine dehydratase
FOC37_15395	COG1253	flavin adenine dinucleotide binding
FOC37_15400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_15400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_15405	COG3715	PTS system
FOC37_15410	COG3716	PTS system mannose fructose sorbose family IID component
FOC37_15415	COG4811	Protein of unknown function (DUF986)
FOC37_15420	COG1971	Probably functions as a manganese efflux pump
FOC37_15430	COG5002	protein histidine kinase activity
FOC37_15430	COG5001	Diguanylate cyclase
FOC37_15430	COG3447	MASE1 domain protein
FOC37_15440	COG2226	methyltransferase
FOC37_15445	COG0768	penicillin binding
FOC37_15455	COG1278	Cold shock
FOC37_15470	COG1113	amino acid transport
FOC37_15505	COG2207	Transcriptional regulator
FOC37_15525	COG1132	(ABC) transporter
FOC37_15535	COG3706	GGDEF domain
FOC37_15535	COG2203	Gaf domain
FOC37_15535	COG5001	Diguanylate cyclase
FOC37_15535	COG4251	negative regulation of phosphorylation
FOC37_15550	COG3755	Protein conserved in bacteria
FOC37_15560	COG0697	spore germination
FOC37_15570	COG1733	regulation of RNA biosynthetic process
FOC37_15575	COG0702	epimerase
FOC37_15580	COG2873	o-acetylhomoserine
FOC37_15590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC37_15600	COG0840	transmembrane signaling receptor activity
FOC37_15605	COG3397	chitin binding
FOC37_15625	COG0538	isocitrate dehydrogenase activity
FOC37_15630	COG1187	pseudouridine synthase activity
FOC37_15640	COG0482	sulfurtransferase activity
FOC37_15645	COG2915	High frequency lysogenization protein hflD homolog
FOC37_15650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC37_15660	COG0745	RESPONSE REGULATOR receiver
FOC37_15670	COG2850	peptidyl-arginine hydroxylation
FOC37_15680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC37_15685	COG1940	carbohydrate kinase activity
FOC37_15690	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC37_15700	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC37_15705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC37_15710	COG3134	Outer membrane lipoprotein
FOC37_15715	COG1252	NADH dehydrogenase
FOC37_15720	COG3150	esterase
FOC37_15735	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FOC37_15740	COG5633	Lipoprotein
FOC37_15745	COG0537	adenosine 5'-monophosphoramidase activity
FOC37_15755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_15755	COG1263	PTS System
FOC37_15760	COG0084	hydrolase, TatD family'
FOC37_15765	COG0470	DNA polymerase III
FOC37_15770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOC37_15775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC37_15780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC37_15785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC37_15795	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_15800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC37_15810	COG0416	fatty acid biosynthetic process
FOC37_15815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC37_15820	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC37_15830	COG0564	pseudouridine synthase activity
FOC37_15835	COG1530	ribonuclease E activity
FOC37_15840	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOC37_15845	COG0418	dihydroorotase activity
FOC37_15875	COG0628	permease
FOC37_15910	COG1560	Kdo2-lipid A biosynthetic process
FOC37_15915	COG2259	Doxx family
FOC37_15920	COG2814	Major facilitator Superfamily
FOC37_15925	COG3104	oligopeptide transport
FOC37_15940	COG5645	(Lipo)protein
FOC37_15945	COG2943	transferase activity, transferring hexosyl groups
FOC37_15950	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FOC37_15980	COG3916	Acyl-homoserine-lactone synthase
FOC37_15985	COG2771	luxR family
FOC37_15990	COG2066	Belongs to the glutaminase family
FOC37_15995	COG0531	amino acid
FOC37_16000	COG0076	glutamate decarboxylase activity
FOC37_16020	COG1470	cell adhesion involved in biofilm formation
FOC37_16020	COG1388	LysM domain
FOC37_16035	COG0549	Belongs to the carbamate kinase family
FOC37_16045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC37_16050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC37_16055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOC37_16060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC37_16065	COG3257	ureidoglycine aminohydrolase activity
FOC37_16070	COG1929	Belongs to the glycerate kinase type-1 family
FOC37_16075	COG2233	PERMEase
FOC37_16085	COG1953	Uracil, thiamine, allantoin
FOC37_16090	COG2084	Dehydrogenase
FOC37_16095	COG3622	Belongs to the hyi family
FOC37_16100	COG3960	tartronate-semialdehyde synthase activity
FOC37_16105	COG1414	Transcriptional regulator
FOC37_16115	COG0583	DNA-binding transcription factor activity
FOC37_16120	COG0745	RESPONSE REGULATOR receiver
FOC37_16120	COG3706	GGDEF domain
FOC37_16125	COG3437	response regulator, receiver
FOC37_16125	COG2205	protein histidine kinase activity
FOC37_16125	COG3850	Histidine kinase
FOC37_16125	COG4999	Histidine kinase
FOC37_16150	COG1215	transferase activity, transferring glycosyl groups
FOC37_16160	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC37_16165	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC37_16170	COG0745	RESPONSE REGULATOR receiver
FOC37_16180	COG0058	SHG alpha-glucan phosphorylase activity
FOC37_16210	COG3121	Chaperone
FOC37_16225	COG3121	Chaperone
FOC37_16230	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FOC37_16255	COG2920	part of a sulfur-relay system
FOC37_16260	COG1254	Belongs to the acylphosphatase family
FOC37_16270	COG3785	DNA binding
FOC37_16275	COG1832	CoA-binding protein
FOC37_16280	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOC37_16290	COG0210	DNA helicase
FOC37_16295	COG3304	Inner membrane component domain
FOC37_16300	COG1289	transmembrane transporter activity
FOC37_16305	COG3070	regulator of competence-specific genes
FOC37_16310	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FOC37_16315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC37_16315	COG2885	chlorophyll binding
FOC37_16320	COG3120	sequence-specific DNA binding
FOC37_16325	COG1067	ATP-dependent peptidase activity
FOC37_16330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC37_16340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC37_16345	COG3130	regulation of translation
FOC37_16350	COG3009	Protein conserved in bacteria
FOC37_16355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC37_16355	COG3008	intermembrane lipid transfer
FOC37_16360	COG2995	paraquat-inducible protein a
FOC37_16365	COG0488	(ABC) transporter
FOC37_16370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC37_16370	COG0116	Belongs to the methyltransferase superfamily
FOC37_16375	COG0633	Ferredoxin
FOC37_16375	COG3217	Mosc domain protein beta barrel domain protein
FOC37_16385	COG0167	dihydroorotate dehydrogenase activity
FOC37_16390	COG0308	aminopeptidase N
FOC37_16395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC37_16400	COG0017	Asparaginyl-tRNA synthetase
FOC37_16410	COG1448	Aminotransferase
FOC37_16415	COG2200	EAL domain
FOC37_16420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC37_16425	COG3108	Peptidase M15
FOC37_16430	COG2989	Protein conserved in bacteria
FOC37_16435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOC37_16440	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FOC37_16445	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FOC37_16450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC37_16455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC37_16460	COG3173	Aminoglycoside phosphotransferase
FOC37_16475	COG2835	tetraacyldisaccharide 4'-kinase activity
FOC37_16480	COG1278	Cold shock
FOC37_16485	COG1278	Cold shock
FOC37_16490	COG5383	Protein conserved in bacteria
FOC37_16495	COG1663	tetraacyldisaccharide 4'-kinase activity
FOC37_16505	COG0658	competence protein
FOC37_16505	COG2333	competence protein COMEC
FOC37_16510	COG0776	regulation of translation
FOC37_16515	COG0539	negative regulation of cytoplasmic translation
FOC37_16525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOC37_16535	COG0252	asparaginase activity
FOC37_16540	COG1944	ATP diphosphatase activity
FOC37_16545	COG2116	formate transmembrane transporter activity
FOC37_16550	COG1882	Formate acetyltransferase
FOC37_16555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC37_16560	COG2814	Major facilitator Superfamily
FOC37_16565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC37_16570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC37_16575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC37_16580	COG3107	peptidoglycan biosynthetic process
FOC37_16580	COG1674	ftsk spoiiie
FOC37_16590	COG0492	ferredoxin-NADP+ reductase activity
FOC37_16600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC37_16610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC37_16615	COG0542	response to heat
FOC37_16620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOC37_16625	COG1278	Cold shock
FOC37_16635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_16640	COG2990	Protein conserved in bacteria
FOC37_16645	COG3593	DNA synthesis involved in DNA repair
FOC37_16650	COG2431	L-lysine efflux transmembrane transporter activity
FOC37_16655	COG1151	hydroxylamine reductase activity
FOC37_16660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC37_16665	COG0028	Belongs to the TPP enzyme family
FOC37_16675	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOC37_16680	COG0702	epimerase
FOC37_16685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_16695	COG1126	abc transporter atp-binding protein
FOC37_16700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_16705	COG4215	(ABC) transporter
FOC37_16710	COG4160	amino acid transport
FOC37_16715	COG1414	Transcriptional regulator
FOC37_16720	COG1012	belongs to the aldehyde dehydrogenase family
FOC37_16725	COG1454	alcohol dehydrogenase
FOC37_16730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC37_16735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_16750	COG1177	transmembrane transport
FOC37_16755	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC37_16760	COG3842	ATPase activity
FOC37_16765	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC37_16780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC37_16785	COG2985	domain, Protein
FOC37_16785	COG0569	domain protein
FOC37_16795	COG0671	phosphoesterase, PA-phosphatase related
FOC37_16800	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC37_16805	COG1349	DNA-binding transcription factor activity
FOC37_16810	COG0814	amino acid
FOC37_16815	COG1760	l-serine dehydratase
FOC37_16820	COG1686	Belongs to the peptidase S11 family
FOC37_16830	COG0626	cystathionine gamma-synthase activity
FOC37_16835	COG2011	ABC-type metal ion transport system permease component
FOC37_16860	COG0625	glutathione transferase activity
FOC37_16865	COG4771	TonB-dependent receptor
FOC37_16870	COG0833	amino acid
FOC37_16875	COG0583	DNA-binding transcription factor activity
FOC37_16880	COG2855	membrane
FOC37_16885	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOC37_16890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC37_16890	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOC37_16890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC37_16895	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC37_16910	COG3005	denitrification pathway
FOC37_16920	COG1349	DNA-binding transcription factor activity
FOC37_16930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_16940	COG3716	PTS system mannose fructose sorbose family IID component
FOC37_16945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_16950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC37_16955	COG2222	sugar isomerase
FOC37_16980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC37_16985	COG1312	Catalyzes the dehydration of D-mannonate
FOC37_16995	COG0246	Mannitol dehydrogenase
FOC37_17000	COG2186	Transcriptional regulator
FOC37_17005	COG0523	cobalamin synthesis protein
FOC37_17010	COG0671	phosphoesterase, PA-phosphatase related
FOC37_17015	COG0791	NLP P60 protein
FOC37_17020	COG2200	EAL domain
FOC37_17025	COG4166	transmembrane transport
FOC37_17030	COG4174	ABC transporter (Permease)
FOC37_17035	COG4239	(ABC) transporter, permease
FOC37_17040	COG4172	Belongs to the ABC transporter superfamily
FOC37_17055	COG2814	Major facilitator Superfamily
FOC37_17060	COG1187	pseudouridine synthase activity
FOC37_17065	COG1061	Type III restriction enzyme res subunit
FOC37_17075	COG3081	Nucleoid-associated protein
FOC37_17080	COG3082	Protein of unknown function (DUF1414)
FOC37_17115	COG3338	carbonate dehydratase activity
FOC37_17120	COG2723	6-phospho-beta-galactosidase activity
FOC37_17125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_17125	COG1263	PTS System
FOC37_17125	COG2190	(PTS) system
FOC37_17175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC37_17190	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_17190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_17195	COG0583	DNA-binding transcription factor activity
FOC37_17200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC37_17200	COG1648	precorrin-2 dehydrogenase activity
FOC37_17210	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC37_17220	COG4865	methylaspartate mutase activity
FOC37_17225	COG3799	methylaspartate ammonia-lyase activity
FOC37_17240	COG1301	dicarboxylic acid transport
FOC37_17255	COG3188	usher protein
FOC37_17300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC37_17315	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC37_17335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC37_17340	COG2223	nitrite transmembrane transporter activity
FOC37_17345	COG2198	Histidine kinase
FOC37_17345	COG0642	Histidine kinase
FOC37_17355	COG2205	protein histidine kinase activity
FOC37_17355	COG0784	Response regulator, receiver
FOC37_17365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC37_17370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC37_17380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC37_17385	COG4574	serine-type endopeptidase inhibitor activity
FOC37_17420	COG0814	amino acid
FOC37_17440	COG1441	menaquinone biosynthetic process
FOC37_17445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC37_17455	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC37_17460	COG1169	isochorismate synthase
FOC37_17465	COG4575	ribosome binding
FOC37_17470	COG0129	dihydroxy-acid dehydratase activity
FOC37_17475	COG4702	Belongs to the UPF0303 family
FOC37_17485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC37_17490	COG1609	Transcriptional regulator
FOC37_17495	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_17500	COG3265	gluconokinase activity
FOC37_17505	COG2731	YhcH YjgK YiaL family protein
FOC37_17520	COG1007	ATP synthesis coupled electron transport
FOC37_17525	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_17530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC37_17535	COG0713	ATP synthesis coupled electron transport
FOC37_17540	COG0839	Belongs to the complex I subunit 6 family
FOC37_17545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_17550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOC37_17555	COG1034	ATP synthesis coupled electron transport
FOC37_17565	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FOC37_17570	COG0649	NAD binding
FOC37_17570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_17575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_17585	COG0583	DNA-binding transcription factor activity
FOC37_17595	COG0436	Aminotransferase
FOC37_17605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOC37_17610	COG0471	metal ion transport
FOC37_17610	COG0490	domain, Protein
FOC37_17615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_17625	COG3092	negative regulation of chromosome organization
FOC37_17635	COG0857	belongs to the CobB CobQ family
FOC37_17635	COG0280	phosphate acetyltransferase
FOC37_17640	COG1609	Transcriptional regulator
FOC37_17645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_17655	COG3037	sugar-specific permease SgaT UlaA
FOC37_17660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOC37_17665	COG0622	Phosphoesterase
FOC37_17675	COG1090	epimerase
FOC37_17685	COG4598	ABC transporter
FOC37_17690	COG4160	amino acid transport
FOC37_17695	COG4215	(ABC) transporter
FOC37_17700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_17705	COG0163	prenyltransferase activity
FOC37_17710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC37_17715	COG1286	toxin biosynthetic process
FOC37_17720	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOC37_17725	COG0285	dihydrofolate synthase activity
FOC37_17735	COG0586	Pfam SNARE associated Golgi protein
FOC37_17745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC37_17770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_17775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC37_17800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC37_17810	COG1794	racemase activity, acting on amino acids and derivatives
FOC37_17815	COG0745	RESPONSE REGULATOR receiver
FOC37_17815	COG3706	GGDEF domain
FOC37_17820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC37_17825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOC37_17825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC37_17835	COG3101	peptidyl-lysine hydroxylation
FOC37_17840	COG0730	response to heat
FOC37_17850	COG5301	cellulose 1,4-beta-cellobiosidase activity
FOC37_17900	COG0741	lytic transglycosylase activity
FOC37_17900	COG1196	nuclear chromosome segregation
FOC37_17900	COG0739	heme binding
FOC37_18010	COG3772	lysozyme
FOC37_18030	COG0305	Participates in initiation and elongation during chromosome replication
FOC37_18035	COG1484	DNA-dependent DNA replication
FOC37_18050	COG4197	protein conserved in bacteria, prophage-related
FOC37_18160	COG0582	viral genome integration into host DNA
FOC37_18165	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FOC37_18170	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC37_18175	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC37_18180	COG2840	Smr protein MutS2
FOC37_18185	COG2062	phosphohistidine phosphatase, SixA
FOC37_18190	COG1024	Enoyl-CoA hydratase
FOC37_18190	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC37_18195	COG0183	Belongs to the thiolase family
FOC37_18200	COG3691	Protein conserved in bacteria
FOC37_18215	COG4235	cytochrome complex assembly
FOC37_18215	COG3088	subunit of a heme lyase
FOC37_18220	COG3088	subunit of a heme lyase
FOC37_18220	COG4235	cytochrome complex assembly
FOC37_18225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC37_18230	COG1138	Cytochrome C-type biogenesis protein
FOC37_18235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOC37_18240	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC37_18245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC37_18250	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC37_18265	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC37_18275	COG0582	viral genome integration into host DNA
FOC37_18375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC37_18430	COG1695	Transcriptional regulator
FOC37_18440	COG2723	6-phospho-beta-galactosidase activity
FOC37_18445	COG1263	PTS System
FOC37_18445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_18450	COG1609	Transcriptional regulator
FOC37_18460	COG2353	YceI-like domain
FOC37_18465	COG3038	cytochrome b561
FOC37_18475	COG0626	cystathionine gamma-synthase activity
FOC37_18495	COG1127	ABC transporter
FOC37_18500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC37_18520	COG0531	amino acid
FOC37_18525	COG2951	lytic endotransglycosylase activity
FOC37_18555	COG2723	6-phospho-beta-galactosidase activity
FOC37_18570	COG0243	molybdopterin cofactor binding
FOC37_18575	COG0437	4 iron, 4 sulfur cluster binding
FOC37_18580	COG3302	dmso reductase anchor subunit
FOC37_18585	COG3381	protein complex oligomerization
FOC37_18595	COG1598	PFAM Uncharacterised protein family UPF0150
FOC37_18605	COG3038	cytochrome b561
FOC37_18610	COG0436	Aminotransferase
FOC37_18625	COG3275	phosphorelay sensor kinase activity
FOC37_18630	COG3279	Response regulator of the LytR AlgR family
FOC37_18635	COG2223	nitrite transmembrane transporter activity
FOC37_18640	COG0837	glucose binding
FOC37_18655	COG0667	Aldo Keto reductase
FOC37_18665	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC37_18670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_18705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC37_18730	COG3530	Putative quorum-sensing-regulated virulence factor
FOC37_18735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC37_18745	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FOC37_18750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC37_18755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_18765	COG2190	(PTS) system
FOC37_18770	COG2205	protein histidine kinase activity
FOC37_18775	COG0745	RESPONSE REGULATOR receiver
FOC37_18780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_18850	COG4208	sulfate ABC transporter
FOC37_18855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOC37_18860	COG4150	thiosulfate binding
FOC37_18865	COG2837	iron assimilation
FOC37_18875	COG3111	PFAM Bacterial OB fold (BOF) protein
FOC37_18955	COG2826	transposase and inactivated derivatives, IS30 family
FOC37_18985	COG0456	acetyltransferase
FOC37_18990	COG0408	coproporphyrinogen oxidase activity
FOC37_18995	COG1671	Belongs to the UPF0178 family
FOC37_19020	COG3005	denitrification pathway
FOC37_19025	COG3043	anaerobic respiration
FOC37_19030	COG0243	molybdopterin cofactor binding
FOC37_19035	COG3062	negative regulation of establishment of protein localization
FOC37_19040	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_19040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_19045	COG2197	response regulator
FOC37_19055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_19100	COG1393	Belongs to the ArsC family
FOC37_19105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC37_19110	COG1876	peptidase activity
FOC37_19120	COG0400	carboxylic ester hydrolase activity
FOC37_19130	COG1444	tRNA N-acetyltransferase activity
FOC37_19140	COG2321	neutral zinc metallopeptidase
FOC37_19150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOC37_19155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC37_19160	COG2716	regulation of RNA biosynthetic process
FOC37_19165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC37_19170	COG0628	permease
FOC37_19175	COG4783	chaperone-mediated protein folding
FOC37_19180	COG1393	Belongs to the ArsC family
FOC37_19185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC37_19190	COG2233	PERMEase
FOC37_19200	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC37_19205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC37_19210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_19225	COG0581	inorganic phosphate transmembrane transporter activity
FOC37_19230	COG0573	inorganic phosphate transmembrane transporter activity
FOC37_19235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC37_19240	COG0248	Ppx GppA phosphatase
FOC37_19250	COG2239	Acts as a magnesium transporter
FOC37_19255	COG5002	protein histidine kinase activity
FOC37_19255	COG5001	Diguanylate cyclase
FOC37_19255	COG3447	MASE1 domain protein
FOC37_19260	COG0443	Heat shock 70 kDa protein
FOC37_19265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_19275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_19280	COG2205	protein histidine kinase activity
FOC37_19285	COG0745	RESPONSE REGULATOR receiver
FOC37_19290	COG3422	double-strand break repair
FOC37_19300	COG1597	lipid kinase activity
FOC37_19305	COG3730	PTS system glucitol sorbitol-specific
FOC37_19320	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_19325	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_19330	COG1349	DNA-binding transcription factor activity
FOC37_19350	COG0351	phosphomethylpyrimidine kinase
FOC37_19370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC37_19370	COG0519	Catalyzes the synthesis of GMP from XMP
FOC37_19375	COG0517	IMP dehydrogenase activity
FOC37_19375	COG0516	GMP reductase activity
FOC37_19385	COG1645	bacterial-type flagellum-dependent swarming motility
FOC37_19400	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC37_19405	COG2976	Protein conserved in bacteria
FOC37_19420	COG1426	Protein conserved in bacteria
FOC37_19430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOC37_19445	COG4953	penicillin-binding protein 1C
FOC37_19450	COG2373	Large extracellular alpha-helical protein
FOC37_19455	COG3468	outer membrane autotransporter barrel domain protein
FOC37_19470	COG2975	iron-sulfur cluster assembly
FOC37_19475	COG0633	Ferredoxin
FOC37_19480	COG0443	Heat shock 70 kDa protein
FOC37_19485	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOC37_19495	COG0822	iron-sulfur transferase activity
FOC37_19505	COG1959	2 iron, 2 sulfur cluster binding
FOC37_19510	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOC37_19515	COG0483	inositol monophosphate 1-phosphatase activity
FOC37_19520	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FOC37_19525	COG3683	transport system, periplasmic component
FOC37_19530	COG3711	transcriptional antiterminator
FOC37_19535	COG2814	Major facilitator Superfamily
FOC37_19545	COG1017	nitric oxide dioxygenase activity
FOC37_19545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC37_19550	COG2188	Transcriptional regulator
FOC37_19560	COG3457	Alanine racemase
FOC37_19565	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FOC37_19580	COG0347	Belongs to the P(II) protein family
FOC37_19585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOC37_19585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC37_19590	COG2204	response regulator
FOC37_19595	COG3170	Tfp pilus assembly protein FimV
FOC37_19600	COG2205	protein histidine kinase activity
FOC37_19615	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC37_19620	COG0590	tRNA wobble adenosine to inosine editing
FOC37_19630	COG0560	Phosphoserine phosphatase
FOC37_19645	COG1737	Transcriptional regulator
FOC37_19650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_19655	COG0736	holo-[acyl-carrier-protein] synthase activity
FOC37_19660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOC37_19665	COG1381	Involved in DNA repair and RecF pathway recombination
FOC37_19670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC37_19680	COG0681	Belongs to the peptidase S26 family
FOC37_19685	COG0481	GTPase activity
FOC37_19695	COG3086	response to oxidative stress
FOC37_19700	COG3026	antisigma factor binding
FOC37_19705	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FOC37_19715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC37_19720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC37_19725	COG0513	Belongs to the DEAD box helicase family
FOC37_19740	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FOC37_19745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC37_19750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC37_19755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC37_19760	COG0497	DNA recombination
FOC37_19765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC37_19775	COG2867	negative regulation of translational initiation
FOC37_19780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOC37_19790	COG0582	viral genome integration into host DNA
FOC37_19825	COG3394	polysaccharide catabolic process
FOC37_19830	COG2169	Transcriptional regulator
FOC37_19830	COG1917	Cupin 2, conserved barrel domain protein
FOC37_19835	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC37_19840	COG2723	6-phospho-beta-galactosidase activity
FOC37_19845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_19850	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_19855	COG2133	pyrroloquinoline quinone binding
FOC37_19860	COG0667	Aldo Keto reductase
FOC37_19870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC37_19875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC37_19885	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FOC37_19890	COG4413	Urea transporter
FOC37_19900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC37_19905	COG0830	nickel cation binding
FOC37_19910	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FOC37_19915	COG0804	urea catabolic process
FOC37_19930	COG1124	(ABC) transporter
FOC37_19940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC37_19945	COG0601	transmembrane transport
FOC37_19975	COG1278	Cold shock
FOC37_19995	COG2207	Transcriptional regulator
FOC37_19995	COG3708	Transcriptional regulator
FOC37_20010	COG4575	ribosome binding
FOC37_20020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC37_20025	COG1780	Probably involved in ribonucleotide reductase function
FOC37_20035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC37_20045	COG4176	ABC-type proline glycine betaine transport system permease component
FOC37_20050	COG2113	Glycine betaine
FOC37_20080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC37_20090	COG2226	methyltransferase
FOC37_20095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC37_20100	COG0741	lytic transglycosylase activity
FOC37_20100	COG1388	LysM domain
FOC37_20105	COG3021	interspecies interaction between organisms
FOC37_20110	COG2814	Major facilitator Superfamily
FOC37_20115	COG0583	DNA-binding transcription factor activity
FOC37_20130	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_20170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC37_20185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC37_20245	COG0542	response to heat
FOC37_20255	COG0564	pseudouridine synthase activity
FOC37_20260	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC37_20265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC37_20270	COG1605	Chorismate mutase
FOC37_20270	COG0077	Prephenate dehydratase
FOC37_20275	COG0287	Prephenate dehydrogenase
FOC37_20275	COG1605	Chorismate mutase
FOC37_20280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC37_20285	COG3279	Response regulator of the LytR AlgR family
FOC37_20290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC37_20295	COG3137	Salt-induced outer membrane protein
FOC37_20300	COG0335	large ribosomal subunit rRNA binding
FOC37_20305	COG0336	Belongs to the RNA methyltransferase TrmD family
FOC37_20315	COG0228	four-way junction DNA binding
FOC37_20320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC37_20325	COG4137	Cytochrome C assembly protein
FOC37_20330	COG4536	flavin adenine dinucleotide binding
FOC37_20335	COG1854	S-ribosylhomocysteine lyase activity
FOC37_20340	COG2918	glutathione biosynthetic process
FOC37_20345	COG1238	metal cluster binding
FOC37_20350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_20385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOC37_20390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC37_20395	COG2137	regulation of response to DNA damage stimulus
FOC37_20400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOC37_20425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC37_20430	COG3958	Transketolase
FOC37_20435	COG3959	Transketolase, thiamine diphosphate binding domain
FOC37_20440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_20445	COG1129	ABC transporter
FOC37_20455	COG1609	Transcriptional regulator
FOC37_20470	COG3381	protein complex oligomerization
FOC37_20475	COG3302	dmso reductase anchor subunit
FOC37_20480	COG0437	4 iron, 4 sulfur cluster binding
FOC37_20485	COG0243	molybdopterin cofactor binding
FOC37_20490	COG1454	alcohol dehydrogenase
FOC37_20495	COG0235	Class ii aldolase
FOC37_20500	COG0738	Major facilitator superfamily
FOC37_20510	COG1070	Carbohydrate kinase
FOC37_20520	COG1349	DNA-binding transcription factor activity
FOC37_20525	COG0235	Class ii aldolase
FOC37_20530	COG1349	DNA-binding transcription factor activity
FOC37_20545	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_20550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_20555	COG3623	hexulose-6-phosphate isomerase
FOC37_20560	COG1070	Carbohydrate kinase
FOC37_20565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_20565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_20575	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC37_20580	COG4177	L-phenylalanine transmembrane transporter activity
FOC37_20585	COG1137	ATPase activity
FOC37_20590	COG0410	ABC transporter
FOC37_20645	COG0640	Transcriptional regulator
FOC37_20650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC37_20655	COG3158	transport of potassium into the cell
FOC37_20660	COG3048	D-serine ammonia-lyase activity
FOC37_20665	COG2610	gluconate transmembrane transporter activity
FOC37_20670	COG0583	DNA-binding transcription factor activity
FOC37_20675	COG4608	Belongs to the ABC transporter superfamily
FOC37_20685	COG0601	transmembrane transport
FOC37_20695	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_20700	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_20720	COG1538	Outer membrane efflux protein
FOC37_20725	COG1136	(ABC) transporter
FOC37_20725	COG0577	efflux transmembrane transporter activity
FOC37_20730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_20745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC37_20760	COG3539	Fimbrial protein
FOC37_20765	COG3539	Fimbrial protein
FOC37_20780	COG3121	Chaperone
FOC37_20785	COG3188	usher protein
FOC37_20810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC37_20815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC37_20820	COG4942	peptidase
FOC37_20820	COG1388	LysM domain
FOC37_20825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOC37_20830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOC37_20835	COG0585	pseudouridine synthase activity
FOC37_20840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOC37_20850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOC37_20860	COG0765	amino acid transport
FOC37_20875	COG0529	Catalyzes the synthesis of activated sulfate
FOC37_20880	COG2895	sulfate adenylyltransferase (ATP) activity
FOC37_20885	COG0175	sulfate reduction
FOC37_20890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC37_20890	COG1648	precorrin-2 dehydrogenase activity
FOC37_20895	COG2234	aminopeptidase activity
FOC37_20910	COG0175	sulfate reduction
FOC37_20915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC37_20920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOC37_20925	COG0720	synthase
FOC37_20930	COG0602	queuosine metabolic process
FOC37_20940	COG0148	phosphopyruvate hydratase activity
FOC37_20945	COG0504	CTP synthase activity
FOC37_20950	COG3956	TIGRFAM MazG family protein
FOC37_20955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC37_20960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC37_20970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC37_20975	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOC37_20980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC37_20990	COG2860	membrane
FOC37_20995	COG0316	Belongs to the HesB IscA family
FOC37_21005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOC37_21015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_21020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC37_21025	COG1120	ATPase activity
FOC37_21030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC37_21035	COG1643	Atp-dependent helicase
FOC37_21040	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC37_21045	COG1489	DNA binding
FOC37_21050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC37_21060	COG0617	tRNA 3'-terminal CCA addition
FOC37_21065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC37_21070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC37_21075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC37_21085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOC37_21090	COG0726	polysaccharide deacetylase
FOC37_21095	COG0842	Transport permease protein
FOC37_21100	COG1131	(ABC) transporter
FOC37_21105	COG0288	reversible hydration of carbon dioxide
FOC37_21110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOC37_21115	COG2132	Multicopper oxidase
FOC37_21125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC37_21130	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC37_21140	COG3112	Uncharacterised protein family (UPF0231)
FOC37_21145	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOC37_21160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_21165	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC37_21170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOC37_21175	COG2186	Transcriptional regulator
FOC37_21180	COG1113	amino acid transport
FOC37_21185	COG3725	Membrane protein required for beta-lactamase induction
FOC37_21200	COG4969	Belongs to the N-Me-Phe pilin family
FOC37_21205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC37_21210	COG1459	type II secretion system
FOC37_21215	COG0516	GMP reductase activity
FOC37_21220	COG0237	dephospho-CoA kinase activity
FOC37_21230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOC37_21235	COG0494	nUDIX hydrolase
FOC37_21240	COG0653	protein targeting
FOC37_21260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC37_21265	COG0849	cell division
FOC37_21270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC37_21280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC37_21285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC37_21290	COG0772	Belongs to the SEDS family
FOC37_21300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC37_21305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC37_21310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC37_21315	COG0768	penicillin binding
FOC37_21320	COG3116	cell division
FOC37_21325	COG0275	rRNA processing
FOC37_21340	COG1609	Transcriptional regulator
FOC37_21350	COG0028	Belongs to the TPP enzyme family
FOC37_21355	COG1022	Amp-dependent synthetase and ligase
FOC37_21360	COG0583	DNA-binding transcription factor activity
FOC37_21370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC37_21375	COG0473	3-isopropylmalate dehydrogenase activity
FOC37_21380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC37_21395	COG3033	Beta-eliminating lyase
FOC37_21400	COG0814	amino acid
FOC37_21405	COG2814	Major facilitator Superfamily
FOC37_21415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC37_21420	COG4533	DNA binding
FOC37_21425	COG4143	(ABC) transporter
FOC37_21430	COG1178	ABC-type Fe3 transport system permease component
FOC37_21440	COG0586	Pfam SNARE associated Golgi protein
FOC37_21450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC37_21455	COG0564	pseudouridine synthase activity
FOC37_21460	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOC37_21465	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC37_21470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC37_21480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC37_21485	COG2967	ApaG domain
FOC37_21490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC37_21495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC37_21505	COG2966	Psort location CytoplasmicMembrane, score
FOC37_21510	COG1280	lysine exporter protein (LysE YggA)
FOC37_21515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC37_21520	COG0505	Belongs to the CarA family
FOC37_21530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOC37_21535	COG1047	Peptidyl-prolyl cis-trans
FOC37_21540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOC37_21545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC37_21550	COG0196	riboflavin kinase activity
FOC37_21565	COG0583	DNA-binding transcription factor activity
FOC37_21570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC37_21575	COG0484	heat shock protein binding
FOC37_21585	COG1584	GPR1 FUN34 yaaH family protein
FOC37_21600	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC37_21605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC37_21610	COG3022	response to hydroperoxide
FOC37_21620	COG0083	homoserine kinase activity
FOC37_21635	COG0745	RESPONSE REGULATOR receiver
FOC37_21640	COG3045	CreA protein
FOC37_21645	COG3708	Transcriptional regulator
FOC37_21645	COG2207	Transcriptional regulator
FOC37_21655	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC37_21660	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FOC37_21665	COG0741	lytic transglycosylase activity
FOC37_21670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC37_21680	COG2199	diguanylate cyclase activity
FOC37_21685	COG2885	chlorophyll binding
FOC37_21690	COG0488	(ABC) transporter
FOC37_21725	COG1454	alcohol dehydrogenase
FOC37_21740	COG0604	alcohol dehydrogenase
FOC37_21755	COG0560	Phosphoserine phosphatase
FOC37_21760	COG3726	membrane protein affecting hemolysin expression
FOC37_21765	COG3550	peptidyl-serine autophosphorylation
FOC37_21775	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOC37_21780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC37_21785	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC37_21790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_21795	COG0084	hydrolase, TatD family'
FOC37_21800	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC37_21810	COG2823	Periplasmic or secreted lipoprotein
FOC37_21815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOC37_21820	COG0456	acetyltransferase
FOC37_21825	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FOC37_21835	COG0667	Aldo Keto reductase
FOC37_21865	COG3706	GGDEF domain
FOC37_21925	COG2192	nodulation
FOC37_21935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_21935	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOC37_21935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC37_21940	COG1461	Dihydroxyacetone kinase
FOC37_21945	COG2376	Dihydroxyacetone kinase
FOC37_21955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_21960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_21965	COG2235	arginine
FOC37_21980	COG0859	PFAM glycosyl transferase family 9
FOC37_21990	COG1070	Carbohydrate kinase
FOC37_21995	COG2390	Transcriptional regulator
FOC37_22000	COG1129	ABC transporter
FOC37_22005	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_22010	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_22015	COG1879	ABC-type sugar transport system periplasmic component
FOC37_22020	COG1830	Aldolase
FOC37_22030	COG0642	Histidine kinase
FOC37_22055	COG3272	Protein of unknown function (DUF1722)
FOC37_22075	COG3423	Transcriptional regulator
FOC37_22080	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_22195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC37_22235	COG0582	viral genome integration into host DNA
FOC37_22285	COG0795	lipopolysaccharide-transporting ATPase activity
FOC37_22290	COG0795	lipopolysaccharide-transporting ATPase activity
FOC37_22295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOC37_22300	COG2927	DNA polymerase III (CHI subunit)
FOC37_22315	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FOC37_22325	COG2731	YhcH YjgK YiaL family protein
FOC37_22335	COG0601	transmembrane transport
FOC37_22345	COG0444	Belongs to the ABC transporter superfamily
FOC37_22350	COG4608	Belongs to the ABC transporter superfamily
FOC37_22355	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_22360	COG0583	DNA-binding transcription factor activity
FOC37_22375	COG2188	Transcriptional regulator
FOC37_22380	COG3624	Phosphonate C-P lyase system protein PhnG
FOC37_22385	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FOC37_22390	COG3626	phosphonate metabolism
FOC37_22395	COG3627	carbon phosphorus lyase activity
FOC37_22400	COG4107	phosphonate C-P lyase system protein PhnK
FOC37_22405	COG4778	phosphonate C-P lyase system protein PhnL
FOC37_22410	COG3454	Phosphonate metabolism
FOC37_22415	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FOC37_22420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC37_22425	COG0702	epimerase
FOC37_22430	COG3787	Belongs to the UPF0306 family
FOC37_22440	COG1982	Orn Lys Arg decarboxylase major
FOC37_22445	COG0531	amino acid
FOC37_22450	COG2827	Endonuclease containing a URI domain
FOC37_22455	COG3153	acetyltransferase
FOC37_22475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC37_22480	COG0513	Belongs to the DEAD box helicase family
FOC37_22495	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC37_22505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC37_22510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOC37_22520	COG0195	Participates in both transcription termination and antitermination
FOC37_22540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC37_22550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC37_22555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC37_22560	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOC37_22565	COG1534	Rna-binding protein
FOC37_22570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC37_22575	COG2027	D-alanyl-D-alanine carboxypeptidase
FOC37_22580	COG0745	RESPONSE REGULATOR receiver
FOC37_22585	COG0642	Histidine kinase
FOC37_22590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC37_22595	COG0697	spore germination
FOC37_22610	COG0142	geranyltranstransferase activity
FOC37_22625	COG3423	Transcriptional regulator