locus-tag	class	description
FOC38_00005	COG0589	response to stress
FOC38_00015	COG0306	phosphate transporter
FOC38_00020	COG2081	HI0933 family
FOC38_00035	COG0583	DNA-binding transcription factor activity
FOC38_00040	COG2814	Major facilitator Superfamily
FOC38_00055	COG3718	enzyme involved in inositol metabolism
FOC38_00070	COG3962	Belongs to the TPP enzyme family
FOC38_00075	COG0673	inositol 2-dehydrogenase activity
FOC38_00080	COG1082	Xylose isomerase domain protein TIM barrel
FOC38_00085	COG1247	-acetyltransferase
FOC38_00090	COG1741	Belongs to the pirin family
FOC38_00095	COG1609	Transcriptional regulator
FOC38_00100	COG2610	gluconate transmembrane transporter activity
FOC38_00105	COG3265	gluconokinase activity
FOC38_00110	COG2095	MarC family integral membrane protein
FOC38_00115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC38_00135	COG3275	phosphorelay sensor kinase activity
FOC38_00140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC38_00145	COG1523	belongs to the glycosyl hydrolase 13 family
FOC38_00150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC38_00155	COG0297	glycogen (starch) synthase activity
FOC38_00160	COG0058	SHG alpha-glucan phosphorylase activity
FOC38_00165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC38_00170	COG1349	DNA-binding transcription factor activity
FOC38_00175	COG0705	Rhomboid family
FOC38_00185	COG2909	trisaccharide binding
FOC38_00190	COG0058	SHG alpha-glucan phosphorylase activity
FOC38_00195	COG1640	4-alpha-glucanotransferase
FOC38_00200	COG0316	Belongs to the HesB IscA family
FOC38_00200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC38_00210	COG0596	Alpha beta hydrolase
FOC38_00230	COG1918	ferrous iron import across plasma membrane
FOC38_00235	COG2183	response to ionizing radiation
FOC38_00240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC38_00245	COG0745	RESPONSE REGULATOR receiver
FOC38_00265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC38_00270	COG1011	Hydrolase
FOC38_00280	COG0494	nUDIX hydrolase
FOC38_00285	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC38_00310	COG4796	Type ii and iii secretion system protein
FOC38_00315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC38_00335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC38_00345	COG0180	Tryptophanyl-tRNA synthetase
FOC38_00350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC38_00350	COG1648	precorrin-2 dehydrogenase activity
FOC38_00360	COG2146	nitrite reductase [NAD(P)H] activity
FOC38_00365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC38_00370	COG0402	S-adenosylhomocysteine deaminase activity
FOC38_00375	COG0738	Major facilitator superfamily
FOC38_00395	COG1486	melibiose metabolic process
FOC38_00400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC38_00405	COG0433	COG0433 Predicted ATPase
FOC38_00420	COG1289	transmembrane transporter activity
FOC38_00430	COG1765	OsmC-like protein
FOC38_00435	COG3954	Phosphoribulokinase
FOC38_00440	COG3089	Belongs to the UPF0270 family
FOC38_00445	COG0429	hydrolase of the alpha beta-hydrolase fold
FOC38_00460	COG4521	taurine ABC transporter
FOC38_00470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC38_00475	COG2175	clavaminate synthase activity
FOC38_00485	COG1216	Glycosyl transferase, family 2
FOC38_00490	COG0488	(ABC) transporter
FOC38_00495	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC38_00505	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOC38_00510	COG1047	Peptidyl-prolyl cis-trans
FOC38_00520	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC38_00525	COG2964	Protein conserved in bacteria
FOC38_00530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOC38_00535	COG2923	Belongs to the DsrF TusC family
FOC38_00540	COG2168	tRNA wobble position uridine thiolation
FOC38_00545	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOC38_00550	COG0049	tRNA binding
FOC38_00560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC38_00575	COG0051	transcription antitermination factor activity, RNA binding
FOC38_00590	COG0089	rRNA binding
FOC38_00600	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOC38_00610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOC38_00615	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOC38_00620	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC38_00625	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOC38_00630	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOC38_00635	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOC38_00645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC38_00650	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOC38_00655	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC38_00660	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOC38_00665	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC38_00670	COG1841	ribosomal large subunit assembly
FOC38_00675	COG0200	Binds to the 23S rRNA
FOC38_00680	COG0201	protein transport
FOC38_00685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC38_00690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC38_00695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOC38_00700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOC38_00710	COG0203	ribosomal protein L17
FOC38_00720	COG0789	Transcriptional regulator
FOC38_00725	COG3036	rescue of stalled ribosome
FOC38_00730	COG1970	mechanosensitive ion channel activity
FOC38_00735	COG0569	domain protein
FOC38_00740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC38_00740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC38_00745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC38_00750	COG0242	peptide deformylase activity
FOC38_00755	COG0758	DNA mediated transformation
FOC38_00765	COG0551	DNA topoisomerase type I activity
FOC38_00770	COG0009	L-threonylcarbamoyladenylate synthase
FOC38_00775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC38_00780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC38_00820	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOC38_00825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC38_00830	COG2224	Isocitrate lyase
FOC38_00835	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FOC38_00840	COG0183	Belongs to the thiolase family
FOC38_00845	COG2031	fatty acid transporter
FOC38_00850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC38_00855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC38_00860	COG2204	response regulator
FOC38_00865	COG3852	Histidine kinase
FOC38_00870	COG1414	Transcriptional regulator
FOC38_00895	COG0527	aspartate kinase activity
FOC38_00905	COG3223	Belongs to the PsiE family
FOC38_00910	COG3833	ABC-type maltose transport systems, permease component
FOC38_00915	COG1175	transmembrane transport
FOC38_00935	COG4580	involved in the transport of maltose and maltodextrins
FOC38_00950	COG3161	chorismate lyase activity
FOC38_00960	COG2937	Belongs to the GPAT DAPAT family
FOC38_00965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC38_00970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOC38_00975	COG3237	CsbD-like
FOC38_00980	COG0735	belongs to the Fur family
FOC38_00990	COG2131	deaminase
FOC38_01035	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOC38_01040	COG5532	Uncharacterized conserved protein (DUF2303)
FOC38_01075	COG3645	SOS response
FOC38_01075	COG3646	Phage regulatory protein
FOC38_01080	COG1403	HNH endonuclease
FOC38_01260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC38_01270	COG0604	alcohol dehydrogenase
FOC38_01275	COG0305	Participates in initiation and elongation during chromosome replication
FOC38_01280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC38_01285	COG1448	Aminotransferase
FOC38_01290	COG2315	Protein conserved in bacteria
FOC38_01295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC38_01300	COG0629	single-stranded DNA binding
FOC38_01305	COG3550	peptidyl-serine autophosphorylation
FOC38_01320	COG2252	PERMEase
FOC38_01325	COG0025	NhaP-type Na H and K H
FOC38_01330	COG0583	DNA-binding transcription factor activity
FOC38_01335	COG1380	Effector of murein hydrolase LrgA
FOC38_01345	COG1126	abc transporter atp-binding protein
FOC38_01350	COG0765	amino acid transport
FOC38_01355	COG4597	amino acid ABC transporter
FOC38_01360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_01370	COG1560	Kdo2-lipid A biosynthetic process
FOC38_01380	COG1129	ABC transporter
FOC38_01385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_01395	COG1069	ribulokinase activity
FOC38_01405	COG0471	metal ion transport
FOC38_01410	COG1278	Cold shock
FOC38_01415	COG1278	Cold shock
FOC38_01420	COG3133	Outer membrane lipoprotein
FOC38_01425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOC38_01430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC38_01435	COG2264	protein methyltransferase activity
FOC38_01440	COG4145	pantothenate transmembrane transporter activity
FOC38_01445	COG3924	membrane
FOC38_01450	COG0439	Biotin carboxylase
FOC38_01455	COG0511	ligase activity, forming carbon-carbon bonds
FOC38_01465	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOC38_01475	COG0604	alcohol dehydrogenase
FOC38_01480	COG2199	diguanylate cyclase activity
FOC38_01480	COG2200	EAL domain
FOC38_01485	COG1077	Cell shape determining protein MreB Mrl
FOC38_01490	COG1792	Involved in formation and maintenance of cell shape
FOC38_01495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOC38_01505	COG1530	ribonuclease E activity
FOC38_01510	COG3164	Protein of unknown function
FOC38_01515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC38_01520	COG0312	modulator of DNA gyrase
FOC38_01525	COG0583	DNA-binding transcription factor activity
FOC38_01535	COG1566	PFAM secretion protein HlyD family protein
FOC38_01540	COG1289	transmembrane transporter activity
FOC38_01545	COG1012	belongs to the aldehyde dehydrogenase family
FOC38_01555	COG2732	(Barnase) inhibitor
FOC38_01560	COG3028	Belongs to the UPF0307 family
FOC38_01565	COG0312	modulator of DNA gyrase
FOC38_01570	COG3783	Cytochrome b(562)
FOC38_01575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC38_01605	COG3964	amidohydrolase
FOC38_01620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_01620	COG3711	transcriptional antiterminator
FOC38_01625	COG3093	addiction module antidote protein HigA
FOC38_01635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC38_01645	COG1263	PTS System
FOC38_01645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_01650	COG0366	Alpha amylase catalytic
FOC38_01665	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOC38_01670	COG0540	Belongs to the ATCase OTCase family
FOC38_01675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC38_01680	COG2271	Major facilitator Superfamily
FOC38_01685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_01690	COG1660	Displays ATPase and GTPase activities
FOC38_01695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_01705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC38_01710	COG1137	ATPase activity
FOC38_01715	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOC38_01720	COG3117	lipopolysaccharide transmembrane transporter activity
FOC38_01725	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOC38_01730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOC38_01730	COG0517	IMP dehydrogenase activity
FOC38_01735	COG0530	calcium, potassium:sodium antiporter activity
FOC38_01740	COG1127	ABC transporter
FOC38_01745	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC38_01750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC38_01755	COG2854	intermembrane phospholipid transfer
FOC38_01760	COG3113	response to antibiotic
FOC38_01765	COG5007	Belongs to the BolA IbaG family
FOC38_01770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC38_01775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC38_01780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC38_01785	COG3105	Protein conserved in bacteria
FOC38_01790	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOC38_01795	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC38_01800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOC38_01805	COG0625	glutathione transferase activity
FOC38_01810	COG2969	positive regulation of protein catabolic process
FOC38_01820	COG0493	'glutamate synthase
FOC38_01825	COG0067	glutamate synthase
FOC38_01825	COG0069	glutamate synthase activity
FOC38_01825	COG0070	glutamate synthase
FOC38_01830	COG1242	4 iron, 4 sulfur cluster binding
FOC38_01835	COG0784	Response regulator, receiver
FOC38_01835	COG2198	Histidine kinase
FOC38_01835	COG5002	protein histidine kinase activity
FOC38_01840	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FOC38_01845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC38_01850	COG2823	Periplasmic or secreted lipoprotein
FOC38_01855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC38_01860	COG0792	nuclease activity
FOC38_01870	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC38_01885	COG1064	alcohol dehydrogenase
FOC38_01890	COG1741	Belongs to the pirin family
FOC38_01895	COG0583	DNA-binding transcription factor activity
FOC38_01900	COG0435	Glutathione S-transferase
FOC38_01905	COG2259	Doxx family
FOC38_01915	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FOC38_01920	COG4575	ribosome binding
FOC38_01935	COG0586	Pfam SNARE associated Golgi protein
FOC38_01950	COG2271	Major facilitator Superfamily
FOC38_01960	COG0246	Mannitol dehydrogenase
FOC38_01965	COG2721	sulfolactate sulfo-lyase activity
FOC38_01975	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOC38_01980	COG0861	Integral membrane protein TerC family
FOC38_01985	COG0673	inositol 2-dehydrogenase activity
FOC38_01990	COG1451	nucleotide metabolic process
FOC38_01995	COG3468	outer membrane autotransporter barrel domain protein
FOC38_02000	COG2813	Specifically methylates the guanine in position
FOC38_02005	COG1902	pentaerythritol trinitrate reductase activity
FOC38_02005	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC38_02015	COG2378	regulation of single-species biofilm formation
FOC38_02025	COG3247	response to pH
FOC38_02030	COG2814	Major facilitator Superfamily
FOC38_02060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC38_02065	COG0358	DNA primase activity
FOC38_02075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC38_02080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC38_02085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC38_02095	COG0617	tRNA 3'-terminal CCA addition
FOC38_02100	COG4991	sh3 domain protein
FOC38_02105	COG3025	triphosphatase activity
FOC38_02110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOC38_02115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOC38_02115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC38_02120	COG0531	amino acid
FOC38_02130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC38_02135	COG3384	dioxygenase
FOC38_02140	COG0754	glutathionylspermidine amidase activity
FOC38_02145	COG5463	Belongs to the UPF0441 family
FOC38_02150	COG1538	Outer membrane efflux protein
FOC38_02155	COG0494	nUDIX hydrolase
FOC38_02160	COG3151	Protein conserved in bacteria
FOC38_02165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC38_02170	COG3150	esterase
FOC38_02175	COG0187	DNA topoisomerase II activity
FOC38_02185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOC38_02190	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC38_02195	COG0745	RESPONSE REGULATOR receiver
FOC38_02200	COG2205	protein histidine kinase activity
FOC38_02205	COG1653	transport
FOC38_02210	COG0667	Aldo Keto reductase
FOC38_02215	COG0583	DNA-binding transcription factor activity
FOC38_02225	COG3716	PTS system mannose fructose sorbose family IID component
FOC38_02230	COG3715	PTS system
FOC38_02235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_02240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC38_02245	COG0204	Acyl-transferase
FOC38_02250	COG2132	Multicopper oxidase
FOC38_02270	COG0656	L-ascorbic acid biosynthetic process
FOC38_02275	COG1979	alcohol dehydrogenase
FOC38_02280	COG2207	Transcriptional regulator
FOC38_02285	COG0586	Pfam SNARE associated Golgi protein
FOC38_02290	COG0626	cystathionine gamma-synthase activity
FOC38_02295	COG0811	peptide transport
FOC38_02300	COG0848	biopolymer transport protein
FOC38_02345	COG4964	Belongs to the GSP D family
FOC38_02375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC38_02380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_02400	COG4774	siderophore transport
FOC38_02410	COG1120	ATPase activity
FOC38_02415	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC38_02420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC38_02425	COG4592	Periplasmic binding protein
FOC38_02430	COG0840	transmembrane signaling receptor activity
FOC38_02450	COG3133	Outer membrane lipoprotein
FOC38_02455	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FOC38_02460	COG0437	4 iron, 4 sulfur cluster binding
FOC38_02465	COG5557	Pfam Polysulphide reductase, NrfD
FOC38_02470	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FOC38_02475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOC38_02480	COG1773	rubredoxin
FOC38_02485	COG0375	protein maturation
FOC38_02490	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC38_02490	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC38_02495	COG0298	carbon dioxide binding
FOC38_02500	COG0409	Hydrogenase expression formation protein
FOC38_02505	COG0309	Hydrogenase expression formation protein (HypE)
FOC38_02510	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC38_02515	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOC38_02520	COG5001	Diguanylate cyclase
FOC38_02530	COG4303	Ethanolamine ammonia lyase large subunit
FOC38_02535	COG4302	ethanolamine ammonia-lyase activity
FOC38_02540	COG0477	Major facilitator Superfamily
FOC38_02555	COG3706	GGDEF domain
FOC38_02555	COG0745	RESPONSE REGULATOR receiver
FOC38_02565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOC38_02570	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC38_02575	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC38_02580	COG4607	ABC-type enterochelin transport system periplasmic component
FOC38_02590	COG4605	iron ion homeostasis
FOC38_02595	COG4604	ABC transporter, ATP-binding protein
FOC38_02655	COG1289	transmembrane transporter activity
FOC38_02690	COG3121	Chaperone
FOC38_02695	COG3121	Chaperone
FOC38_02700	COG3188	usher protein
FOC38_02730	COG2040	homocysteine
FOC38_02735	COG0833	amino acid
FOC38_02740	COG1230	cation diffusion facilitator family transporter
FOC38_02775	COG3038	cytochrome b561
FOC38_02780	COG0789	Transcriptional regulator
FOC38_02790	COG0300	oxidoreductase activity
FOC38_02805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC38_02820	COG3447	MASE1 domain protein
FOC38_02820	COG5002	protein histidine kinase activity
FOC38_02820	COG5001	Diguanylate cyclase
FOC38_02825	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC38_02840	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FOC38_02845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_02845	COG2190	(PTS) system
FOC38_02845	COG1263	PTS System
FOC38_02865	COG2188	Transcriptional regulator
FOC38_02870	COG2771	luxR family
FOC38_02875	COG3916	Acyl-homoserine-lactone synthase
FOC38_02880	COG4810	utilization protein
FOC38_02885	COG4917	ethanolamine utilization protein
FOC38_02890	COG4766	ethanolamine catabolic process
FOC38_02905	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC38_02910	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FOC38_02920	COG4820	ethanolamine utilization protein (EutJ)
FOC38_02940	COG4303	Ethanolamine ammonia lyase large subunit
FOC38_02950	COG4816	utilization protein
FOC38_02965	COG2207	Transcriptional regulator
FOC38_02980	COG0305	Participates in initiation and elongation during chromosome replication
FOC38_03015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC38_03160	COG0789	Transcriptional regulator
FOC38_03175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC38_03245	COG2132	Multicopper oxidase
FOC38_03260	COG2205	protein histidine kinase activity
FOC38_03265	COG0745	RESPONSE REGULATOR receiver
FOC38_03270	COG1276	copper resistance
FOC38_03275	COG2372	response to copper ion
FOC38_03280	COG3667	copper resistance
FOC38_03285	COG2132	Multicopper oxidase
FOC38_03300	COG0739	heme binding
FOC38_03340	COG0745	RESPONSE REGULATOR receiver
FOC38_03355	COG4251	negative regulation of phosphorylation
FOC38_03355	COG5001	Diguanylate cyclase
FOC38_03355	COG3706	GGDEF domain
FOC38_03355	COG2203	Gaf domain
FOC38_03380	COG0431	NADPH-dependent FMN reductase
FOC38_03395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC38_03405	COG1982	Orn Lys Arg decarboxylase major
FOC38_03415	COG0741	lytic transglycosylase activity
FOC38_03425	COG1194	a g-specific adenine glycosylase
FOC38_03430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOC38_03435	COG3171	Protein conserved in bacteria
FOC38_03440	COG2066	Belongs to the glutaminase family
FOC38_03450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC38_03455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC38_03460	COG1872	DUF167
FOC38_03465	COG0762	integral membrane protein
FOC38_03470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC38_03475	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC38_03480	COG2805	Type II/IV secretion system protein
FOC38_03490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC38_03495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOC38_03500	COG1678	Uncharacterized ACR, COG1678
FOC38_03505	COG0189	ligase activity
FOC38_03510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC38_03515	COG2356	endonuclease I
FOC38_03520	COG3091	SprT-like family
FOC38_03525	COG0640	Transcriptional regulator
FOC38_03535	COG2391	methyltransferase activity
FOC38_03540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC38_03545	COG1166	arginine decarboxylase activity
FOC38_03555	COG0501	Belongs to the peptidase M48B family
FOC38_03560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC38_03565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC38_03570	COG0126	phosphoglycerate kinase activity
FOC38_03575	COG0191	fructose-bisphosphate aldolase activity
FOC38_03585	COG1279	arginine transmembrane transporter activity
FOC38_03595	COG0583	DNA-binding transcription factor activity
FOC38_03600	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC38_03605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC38_03610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC38_03620	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOC38_03625	COG3079	Belongs to the UPF0149 family
FOC38_03630	COG0006	proline dipeptidase activity
FOC38_03635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC38_03640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC38_03645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC38_03650	COG0509	glycine decarboxylation via glycine cleavage system
FOC38_03655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC38_03655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC38_03660	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_03670	COG1272	protein, Hemolysin III
FOC38_03675	COG0354	folic acid binding
FOC38_03680	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOC38_03690	COG0745	RESPONSE REGULATOR receiver
FOC38_03695	COG2205	protein histidine kinase activity
FOC38_03700	COG4452	Inner membrane protein CreD
FOC38_03705	COG0716	FMN binding
FOC38_03710	COG4974	Belongs to the 'phage' integrase family
FOC38_03715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC38_03720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC38_03750	COG3706	GGDEF domain
FOC38_03755	COG1522	sequence-specific DNA binding
FOC38_03770	COG2271	Major facilitator Superfamily
FOC38_03780	COG0484	heat shock protein binding
FOC38_03790	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_03795	COG1733	regulation of RNA biosynthetic process
FOC38_03800	COG0288	reversible hydration of carbon dioxide
FOC38_03820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC38_03830	COG2165	general secretion pathway protein
FOC38_03835	COG2165	general secretion pathway protein
FOC38_03895	COG0583	DNA-binding transcription factor activity
FOC38_03900	COG0583	DNA-binding transcription factor activity
FOC38_03905	COG0019	diaminopimelate decarboxylase activity
FOC38_03915	COG1609	Transcriptional regulator
FOC38_03925	COG0318	PFAM AMP-dependent synthetase and ligase
FOC38_03925	COG0204	Acyl-transferase
FOC38_03930	COG0477	Major facilitator Superfamily
FOC38_03935	COG0667	Aldo Keto reductase
FOC38_03940	COG0861	Integral membrane protein TerC family
FOC38_03945	COG3066	DNA modification
FOC38_03960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOC38_03970	COG2165	general secretion pathway protein
FOC38_03975	COG4795	General secretion pathway protein
FOC38_03990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOC38_03995	COG1025	Belongs to the peptidase M16 family
FOC38_04000	COG1074	ATP-dependent DNA helicase activity
FOC38_04005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC38_04010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC38_04010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOC38_04015	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC38_04035	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOC38_04040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC38_04045	COG2166	iron-sulfur cluster assembly
FOC38_04050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC38_04060	COG0583	DNA-binding transcription factor activity
FOC38_04065	COG2363	Small membrane protein
FOC38_04070	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOC38_04075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC38_04080	COG1611	Belongs to the LOG family
FOC38_04085	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC38_04085	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC38_04095	COG3098	single-species biofilm formation
FOC38_04100	COG0564	pseudouridine synthase activity
FOC38_04115	COG2171	N-acyltransferase activity
FOC38_04120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOC38_04125	COG0024	Methionine aminopeptidase
FOC38_04130	COG0052	Belongs to the universal ribosomal protein uS2 family
FOC38_04135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOC38_04140	COG0528	UMP kinase activity
FOC38_04145	COG0233	cytoplasmic translational termination
FOC38_04150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC38_04155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC38_04160	COG0575	Belongs to the CDS family
FOC38_04165	COG0750	zinc metalloprotease
FOC38_04175	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOC38_04185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC38_04190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC38_04195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC38_04200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC38_04210	COG0825	malonyl-CoA metabolic process
FOC38_04220	COG0346	lactoylglutathione lyase activity
FOC38_04225	COG0037	tRNA processing
FOC38_04235	COG4568	rho-dependent transcription termination
FOC38_04245	COG4681	YaeQ
FOC38_04255	COG3015	lipoprotein NlpE involved in copper resistance
FOC38_04260	COG0442	prolyl-tRNA aminoacylation
FOC38_04265	COG1720	tRNA m6t6A37 methyltransferase activity
FOC38_04275	COG1464	Belongs to the NlpA lipoprotein family
FOC38_04280	COG2011	ABC-type metal ion transport system permease component
FOC38_04290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC38_04325	COG5544	Lipoprotein
FOC38_04330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC38_04335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC38_04335	COG1042	CoA-binding domain protein
FOC38_04335	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC38_04345	COG3118	belongs to the thioredoxin family
FOC38_04350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC38_04355	COG2814	Major facilitator Superfamily
FOC38_04360	COG1566	PFAM secretion protein HlyD family protein
FOC38_04370	COG1846	Transcriptional regulator
FOC38_04380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOC38_04385	COG2814	Major facilitator Superfamily
FOC38_04395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC38_04410	COG0436	Aminotransferase
FOC38_04415	COG0582	viral genome integration into host DNA
FOC38_04430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC38_04530	COG1192	Involved in chromosome partitioning
FOC38_04560	COG0305	Participates in initiation and elongation during chromosome replication
FOC38_04625	COG3772	lysozyme
FOC38_04760	COG0235	Class ii aldolase
FOC38_04770	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC38_04780	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC38_04795	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
FOC38_04800	COG1960	acyl-CoA dehydrogenase activity
FOC38_04805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC38_04810	COG0121	glutamine amidotransferase
FOC38_04815	COG3034	peptidoglycan biosynthetic process
FOC38_04820	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC38_04825	COG1805	sodium ion transport
FOC38_04830	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC38_04835	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC38_04840	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC38_04845	COG2871	sodium ion transport
FOC38_04850	COG1477	protein flavinylation
FOC38_04855	COG2991	Protein conserved in bacteria
FOC38_04865	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC38_04870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC38_04875	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC38_04895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC38_04900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC38_04905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC38_04910	COG2313	pseudouridylate synthase activity
FOC38_04915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC38_04925	COG3459	Glycosyltransferase 36 associated
FOC38_04940	COG2226	methyltransferase
FOC38_04955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC38_04960	COG3123	guanosine phosphorylase activity
FOC38_04965	COG2974	May be involved in recombination
FOC38_04970	COG1940	carbohydrate kinase activity
FOC38_04975	COG0419	ATPase involved in DNA repair
FOC38_04980	COG0420	3'-5' exonuclease activity
FOC38_04985	COG0745	RESPONSE REGULATOR receiver
FOC38_04990	COG5002	protein histidine kinase activity
FOC38_05000	COG1114	Component of the transport system for branched-chain amino acids
FOC38_05010	COG0366	Alpha amylase catalytic
FOC38_05025	COG0450	alkyl hydroperoxide reductase
FOC38_05030	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FOC38_05035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC38_05045	COG1862	Preprotein translocase
FOC38_05050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC38_05055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC38_05065	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC38_05070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC38_05070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC38_05075	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOC38_05085	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOC38_05090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC38_05095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC38_05100	COG0142	geranyltranstransferase activity
FOC38_05110	COG0301	tRNA thio-modification
FOC38_05110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC38_05115	COG0693	protein deglycase activity
FOC38_05120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC38_05125	COG1666	GTP binding
FOC38_05130	COG2814	Major facilitator Superfamily
FOC38_05135	COG0109	protoheme IX farnesyltransferase activity
FOC38_05140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOC38_05145	COG1845	cytochrome c oxidase, subunit III
FOC38_05150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC38_05155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC38_05165	COG2223	nitrite transmembrane transporter activity
FOC38_05170	COG3056	Lipoprotein
FOC38_05175	COG0271	Belongs to the BolA IbaG family
FOC38_05190	COG0740	serine-type endopeptidase activity
FOC38_05195	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC38_05200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC38_05205	COG0776	regulation of translation
FOC38_05210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC38_05215	COG1555	photosystem II stabilization
FOC38_05220	COG0824	Thioesterase
FOC38_05225	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC38_05230	COG4533	DNA binding
FOC38_05235	COG0561	phosphatase activity
FOC38_05245	COG1522	sequence-specific DNA binding
FOC38_05250	COG1132	(ABC) transporter
FOC38_05255	COG1132	(ABC) transporter
FOC38_05260	COG0347	Belongs to the P(II) protein family
FOC38_05265	COG0004	ammonium transporteR
FOC38_05270	COG1946	Acyl-CoA thioesterase
FOC38_05275	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FOC38_05280	COG3695	enzyme binding
FOC38_05290	COG0582	viral genome integration into host DNA
FOC38_05350	COG1121	(ABC) transporter
FOC38_05355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC38_05360	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC38_05365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC38_05370	COG0254	rRNA binding
FOC38_05375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC38_05380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_05385	COG1309	transcriptional regulator
FOC38_05390	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOC38_05395	COG3264	Mechanosensitive ion channel
FOC38_05395	COG1196	nuclear chromosome segregation
FOC38_05410	COG2832	Protein of unknown function (DUF454)
FOC38_05415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC38_05425	COG0346	lactoylglutathione lyase activity
FOC38_05430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC38_05435	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOC38_05440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOC38_05445	COG0326	Molecular chaperone. Has ATPase activity
FOC38_05450	COG0563	adenylate kinase activity
FOC38_05455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOC38_05480	COG1216	Glycosyl transferase, family 2
FOC38_05480	COG1442	glycosyl transferase family 8
FOC38_05485	COG0463	Glycosyl transferase, family 2
FOC38_05495	COG0438	transferase activity, transferring glycosyl groups
FOC38_05520	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC38_05525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC38_05530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC38_05530	COG4651	solute:proton antiporter activity
FOC38_05535	COG2223	nitrite transmembrane transporter activity
FOC38_05540	COG0737	Belongs to the 5'-nucleotidase family
FOC38_05545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC38_05550	COG3735	TraB family
FOC38_05555	COG2217	Heavy metal translocating P-type atpase
FOC38_05560	COG0789	Transcriptional regulator
FOC38_05565	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC38_05570	COG0330	HflC and HflK could
FOC38_05575	COG3118	belongs to the thioredoxin family
FOC38_05580	COG0300	oxidoreductase activity
FOC38_05585	COG2755	lipolytic protein G-D-S-L family
FOC38_05590	COG4181	ATPase activity
FOC38_05595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOC38_05600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC38_05605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC38_05610	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC38_05615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC38_05620	COG0215	cysteine-tRNA ligase activity
FOC38_05625	COG2501	S4 domain
FOC38_05630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOC38_05640	COG0582	viral genome integration into host DNA
FOC38_05710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC38_05710	COG2169	Transcriptional regulator
FOC38_05715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC38_05725	COG2315	Protein conserved in bacteria
FOC38_05920	COG2246	polysaccharide biosynthetic process
FOC38_05955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC38_05960	COG1328	CTP reductase activity
FOC38_05970	COG2211	Major facilitator Superfamily
FOC38_05980	COG3423	Transcriptional regulator
FOC38_06055	COG4382	Mu-like prophage protein Gp16
FOC38_06110	COG4383	Mu-like prophage protein gp29
FOC38_06135	COG4397	Mu-like prophage major head subunit gpT
FOC38_06160	COG4386	tail sheath protein
FOC38_06225	COG1486	melibiose metabolic process
FOC38_06230	COG2169	Transcriptional regulator
FOC38_06240	COG3240	lipase activity
FOC38_06315	COG3122	Protein conserved in bacteria
FOC38_06355	COG0583	DNA-binding transcription factor activity
FOC38_06370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOC38_06375	COG0583	DNA-binding transcription factor activity
FOC38_06380	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_06390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC38_06420	COG1902	pentaerythritol trinitrate reductase activity
FOC38_06430	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_06440	COG2610	gluconate transmembrane transporter activity
FOC38_06455	COG1940	carbohydrate kinase activity
FOC38_06460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC38_06465	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_06470	COG1129	ABC transporter
FOC38_06475	COG1879	ABC-type sugar transport system periplasmic component
FOC38_06480	COG1737	Transcriptional regulator
FOC38_06485	COG0698	ribose 5-phosphate isomerase
FOC38_06490	COG2850	peptidyl-arginine hydroxylation
FOC38_06495	COG5265	(ABC) transporter
FOC38_06510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC38_06520	COG2197	response regulator
FOC38_06525	COG1278	Cold shock
FOC38_06530	COG1278	Cold shock
FOC38_06535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC38_06540	COG3706	GGDEF domain
FOC38_06545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC38_06550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOC38_06555	COG0321	lipoyl(octanoyl) transferase activity
FOC38_06560	COG2921	Belongs to the UPF0250 family
FOC38_06565	COG1686	Belongs to the peptidase S11 family
FOC38_06570	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOC38_06575	COG0772	Belongs to the SEDS family
FOC38_06580	COG0768	penicillin binding
FOC38_06590	COG0799	negative regulation of ribosome biogenesis
FOC38_06595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC38_06600	COG1466	dna polymerase III delta subunit
FOC38_06605	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FOC38_06610	COG0495	leucyl-tRNA aminoacylation
FOC38_06615	COG2888	peptidyl-tyrosine sulfation
FOC38_06625	COG1126	abc transporter atp-binding protein
FOC38_06630	COG0765	amino acid transport
FOC38_06635	COG0765	amino acid transport
FOC38_06650	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOC38_06655	COG4535	Mg2 and Co2 transporter CorC
FOC38_06660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOC38_06665	COG1702	phosphate starvation-inducible protein PhoH
FOC38_06670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC38_06675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC38_06710	COG0367	asparagine synthase
FOC38_06715	COG0647	UMP catabolic process
FOC38_06720	COG1846	Transcriptional regulator
FOC38_06720	COG1940	carbohydrate kinase activity
FOC38_06725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC38_06730	COG0363	glucosamine-6-phosphate deaminase activity
FOC38_06735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_06735	COG1263	PTS System
FOC38_06735	COG2190	(PTS) system
FOC38_06740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC38_06760	COG0735	belongs to the Fur family
FOC38_06770	COG0840	transmembrane signaling receptor activity
FOC38_06780	COG0596	Alpha beta hydrolase
FOC38_06785	COG2831	hemolysin activation secretion protein
FOC38_06790	COG3210	domain, Protein
FOC38_06855	COG3210	domain, Protein
FOC38_06875	COG3316	Transposase and inactivated derivatives
FOC38_06910	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOC38_06915	COG0033	Phosphoglucomutase
FOC38_06925	COG0745	RESPONSE REGULATOR receiver
FOC38_06930	COG2205	protein histidine kinase activity
FOC38_06935	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOC38_06940	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOC38_06960	COG3272	Protein of unknown function (DUF1722)
FOC38_06970	COG5212	phosphodiesterase
FOC38_06975	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC38_06980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC38_06985	COG1984	allophanate hydrolase subunit 2
FOC38_06990	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOC38_07015	COG2009	succinate dehydrogenase
FOC38_07020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOC38_07025	COG1053	succinate dehydrogenase
FOC38_07035	COG0567	Dehydrogenase, E1 component
FOC38_07040	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC38_07045	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC38_07050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC38_07055	COG0737	Belongs to the 5'-nucleotidase family
FOC38_07060	COG1271	oxidase subunit
FOC38_07065	COG1294	oxidase, subunit
FOC38_07070	COG4890	Cyd operon protein YbgT
FOC38_07075	COG3790	cyd operon protein YbgE
FOC38_07080	COG0824	Thioesterase
FOC38_07085	COG0811	peptide transport
FOC38_07090	COG0848	biopolymer transport protein
FOC38_07095	COG3064	Membrane
FOC38_07095	COG3064	Membrane
FOC38_07100	COG0823	Involved in the tonB-independent uptake of proteins
FOC38_07105	COG2885	chlorophyll binding
FOC38_07110	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOC38_07140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC38_07150	COG1230	cation diffusion facilitator family transporter
FOC38_07155	COG2205	protein histidine kinase activity
FOC38_07155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_07160	COG2197	response regulator
FOC38_07165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC38_07170	COG0588	phosphoglycerate mutase activity
FOC38_07180	COG2017	converts alpha-aldose to the beta-anomer
FOC38_07185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC38_07195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC38_07205	COG1119	ATPase activity
FOC38_07210	COG3585	molybdate ion transport
FOC38_07210	COG2005	Transcriptional regulator
FOC38_07220	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC38_07225	COG4149	molybdate abc transporter
FOC38_07235	COG0561	phosphatase activity
FOC38_07240	COG2706	6-phosphogluconolactonase activity
FOC38_07250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC38_07260	COG2226	methyltransferase
FOC38_07265	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOC38_07275	COG0556	nucleotide-excision repair
FOC38_07280	COG4628	conserved protein (DUF2132)
FOC38_07285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC38_07290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC38_07295	COG0315	cyclic pyranopterin monophosphate synthase activity
FOC38_07300	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOC38_07305	COG0314	molybdopterin synthase activity
FOC38_07310	COG0670	Belongs to the BI1 family
FOC38_07315	COG0842	Transport permease protein
FOC38_07320	COG0842	Transport permease protein
FOC38_07325	COG1131	(ABC) transporter
FOC38_07330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_07335	COG1309	transcriptional regulator
FOC38_07340	COG0513	Belongs to the DEAD box helicase family
FOC38_07345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC38_07350	COG2239	Acts as a magnesium transporter
FOC38_07360	COG1686	Belongs to the peptidase S11 family
FOC38_07365	COG0277	FAD linked oxidase domain protein
FOC38_07375	COG1403	HNH endonuclease
FOC38_07385	COG2261	transglycosylase associated protein
FOC38_07395	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOC38_07410	COG4807	Protein conserved in bacteria
FOC38_07430	COG0411	ABC transporter
FOC38_07440	COG2897	thiosulfate sulfurtransferase activity
FOC38_07445	COG0673	inositol 2-dehydrogenase activity
FOC38_07455	COG1732	Glycine betaine
FOC38_07460	COG1174	glycine betaine transport
FOC38_07465	COG1125	glycine betaine transport
FOC38_07470	COG1174	glycine betaine transport
FOC38_07485	COG0583	DNA-binding transcription factor activity
FOC38_07495	COG0697	spore germination
FOC38_07515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC38_07520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC38_07525	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOC38_07530	COG1126	abc transporter atp-binding protein
FOC38_07535	COG0765	amino acid transport
FOC38_07540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_07545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC38_07555	COG4106	trans-aconitate 2-methyltransferase activity
FOC38_07570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC38_07590	COG0488	(ABC) transporter
FOC38_07595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC38_07600	COG0303	'Molybdopterin
FOC38_07610	COG0477	Major facilitator Superfamily
FOC38_07620	COG1136	(ABC) transporter
FOC38_07650	COG0583	DNA-binding transcription factor activity
FOC38_07655	COG0477	Major facilitator Superfamily
FOC38_07660	COG0302	gtp cyclohydrolase
FOC38_07665	COG2311	Membrane
FOC38_07670	COG1609	Transcriptional regulator
FOC38_07690	COG2116	formate transmembrane transporter activity
FOC38_07695	COG3604	Transcriptional regulator
FOC38_07700	COG3383	formate dehydrogenase (NAD+) activity
FOC38_07705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC38_07710	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOC38_07720	COG3260	NADH ubiquinone oxidoreductase 20
FOC38_07725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC38_07730	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FOC38_07730	COG3261	NADH dehydrogenase
FOC38_07735	COG0651	ATP synthesis coupled electron transport
FOC38_07740	COG4237	Hydrogenase 4 membrane
FOC38_07745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC38_07750	COG0650	Formate hydrogenlyase subunit 4
FOC38_07755	COG0651	ATP synthesis coupled electron transport
FOC38_07760	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC38_07765	COG0375	protein maturation
FOC38_07770	COG0298	carbon dioxide binding
FOC38_07775	COG2949	membrane
FOC38_07780	COG0281	malic enzyme
FOC38_07790	COG1346	cytolysis
FOC38_07795	COG1380	Effector of murein hydrolase LrgA
FOC38_07800	COG2814	Major facilitator Superfamily
FOC38_07820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC38_07820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC38_07825	COG0489	protein tyrosine kinase activity
FOC38_07830	COG0572	uridine kinase
FOC38_07840	COG2982	Protein involved in outer membrane biogenesis
FOC38_07845	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC38_07850	COG1253	flavin adenine dinucleotide binding
FOC38_07855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC38_07860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC38_07865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC38_07870	COG0140	phosphoribosyl-ATP diphosphatase activity
FOC38_07870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOC38_07875	COG0107	imidazoleglycerol-phosphate synthase activity
FOC38_07885	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOC38_07890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC38_07890	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC38_07895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC38_07905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOC38_07915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC38_07920	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_07925	COG1129	ABC transporter
FOC38_07930	COG0371	Dehydrogenase
FOC38_07940	COG0531	amino acid
FOC38_07945	COG2925	Exonuclease
FOC38_07970	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_07975	COG1129	ABC transporter
FOC38_07980	COG1879	ABC-type sugar transport system periplasmic component
FOC38_07990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC38_08000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC38_08010	COG4810	utilization protein
FOC38_08020	COG4656	Part of a membrane complex involved in electron transport
FOC38_08035	COG2096	Adenosyltransferase
FOC38_08060	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC38_08095	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC38_08115	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOC38_08125	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FOC38_08130	COG2241	protein methyltransferase activity
FOC38_08140	COG2875	Belongs to the precorrin methyltransferase family
FOC38_08190	COG1492	cobalamin metabolic process
FOC38_08210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOC38_08215	COG0583	DNA-binding transcription factor activity
FOC38_08225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOC38_08230	COG2211	Major facilitator Superfamily
FOC38_08235	COG0137	argininosuccinate synthase activity
FOC38_08240	COG0534	Mate efflux family protein
FOC38_08245	COG0784	Response regulator, receiver
FOC38_08245	COG0835	chemotaxis
FOC38_08265	COG0561	phosphatase activity
FOC38_08270	COG1349	DNA-binding transcription factor activity
FOC38_08280	COG0583	DNA-binding transcription factor activity
FOC38_08305	COG3047	cAMP biosynthetic process
FOC38_08305	COG2885	chlorophyll binding
FOC38_08335	COG1388	LysM domain
FOC38_08335	COG0791	NLP P60 protein
FOC38_08400	COG3121	Chaperone
FOC38_08425	COG2205	protein histidine kinase activity
FOC38_08425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_08440	COG3842	ATPase activity
FOC38_08450	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC38_08455	COG2271	Major facilitator Superfamily
FOC38_08470	COG4565	transcriptional regulatory protein
FOC38_08475	COG3290	protein histidine kinase activity
FOC38_08480	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FOC38_08485	COG3052	prosthetic group binding
FOC38_08490	COG2301	Belongs to the HpcH HpaI aldolase family
FOC38_08495	COG3051	citrate lyase alpha subunit
FOC38_08510	COG0471	metal ion transport
FOC38_08525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC38_08535	COG2814	Major facilitator Superfamily
FOC38_08545	COG2211	Major facilitator Superfamily
FOC38_08560	COG2204	response regulator
FOC38_08595	COG0251	oxidation-reduction process
FOC38_08610	COG3228	Belongs to the MtfA family
FOC38_08630	COG3121	Chaperone
FOC38_08645	COG3121	Chaperone
FOC38_08650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC38_08680	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_08680	COG0604	alcohol dehydrogenase
FOC38_08680	COG3321	synthase
FOC38_08685	COG3250	beta-galactosidase activity
FOC38_08690	COG1609	Transcriptional regulator
FOC38_08695	COG1278	Cold shock
FOC38_08705	COG0840	transmembrane signaling receptor activity
FOC38_08710	COG1285	pathogenesis
FOC38_08720	COG2130	NADP-dependent
FOC38_08725	COG0589	response to stress
FOC38_08750	COG0643	Histidine kinase
FOC38_08750	COG2198	Histidine kinase
FOC38_08755	COG0835	chemotaxis
FOC38_08760	COG0840	transmembrane signaling receptor activity
FOC38_08765	COG0840	transmembrane signaling receptor activity
FOC38_08770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC38_08780	COG0745	RESPONSE REGULATOR receiver
FOC38_08785	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOC38_08790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC38_08795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC38_08810	COG3418	PFAM FlgN family protein
FOC38_08815	COG2747	anti-sigma28 factor FlgM
FOC38_08825	COG1815	bacterial-type flagellum-dependent cell motility
FOC38_08830	COG1558	bacterial-type flagellum-dependent cell motility
FOC38_08835	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOC38_08840	COG1749	Flagellar hook protein flgE
FOC38_08850	COG4786	Flagellar basal body rod
FOC38_08870	COG1256	bacterial-type flagellum assembly
FOC38_08875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC38_08920	COG2882	bacterial-type flagellum organization
FOC38_08930	COG1317	bacterial-type flagellum organization
FOC38_08935	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC38_08945	COG1677	Flagellar hook-basal body complex protein FliE
FOC38_08950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC38_08955	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOC38_08985	COG1191	sigma factor activity
FOC38_08995	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC38_09025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC38_09025	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC38_09025	COG0506	proline dehydrogenase activity
FOC38_09030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC38_09070	COG1113	amino acid transport
FOC38_09080	COG2199	diguanylate cyclase activity
FOC38_09080	COG2203	Gaf domain
FOC38_09100	COG0366	Alpha amylase catalytic
FOC38_09105	COG0840	transmembrane signaling receptor activity
FOC38_09115	COG3136	membrane protein required for alginate biosynthesis
FOC38_09125	COG2197	response regulator
FOC38_09130	COG0322	excinuclease ABC activity
FOC38_09135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC38_09235	COG3121	Chaperone
FOC38_09240	COG3188	usher protein
FOC38_09255	COG2197	response regulator
FOC38_09275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC38_09280	COG0561	phosphatase activity
FOC38_09285	COG2223	nitrite transmembrane transporter activity
FOC38_09295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC38_09305	COG2197	response regulator
FOC38_09310	COG2223	nitrite transmembrane transporter activity
FOC38_09315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC38_09320	COG1140	nitrate reductase beta subunit
FOC38_09325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC38_09330	COG2181	nitrate reductase activity
FOC38_09340	COG3493	citrate carrier protein
FOC38_09345	COG4565	transcriptional regulatory protein
FOC38_09350	COG3290	protein histidine kinase activity
FOC38_09355	COG1349	DNA-binding transcription factor activity
FOC38_09360	COG2084	Dehydrogenase
FOC38_09365	COG3395	kinase activity
FOC38_09370	COG0235	Class ii aldolase
FOC38_09375	COG3622	Belongs to the hyi family
FOC38_09385	COG1609	Transcriptional regulator
FOC38_09390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC38_09395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC38_09400	COG2723	6-phospho-beta-galactosidase activity
FOC38_09405	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC38_09415	COG0672	)-iron permease
FOC38_09430	COG0577	efflux transmembrane transporter activity
FOC38_09430	COG1136	(ABC) transporter
FOC38_09440	COG1136	(ABC) transporter
FOC38_09440	COG0577	efflux transmembrane transporter activity
FOC38_09465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC38_09470	COG0006	proline dipeptidase activity
FOC38_09475	COG0457	Tetratricopeptide repeat
FOC38_09480	COG0726	polysaccharide deacetylase
FOC38_09480	COG1649	PFAM Uncharacterised BCR, COG1649
FOC38_09485	COG1215	transferase activity, transferring glycosyl groups
FOC38_09490	COG3658	cytochrome
FOC38_09500	COG1702	phosphate starvation-inducible protein PhoH
FOC38_09505	COG0387	Pfam Sodium calcium exchanger
FOC38_09515	COG2814	Major facilitator Superfamily
FOC38_09520	COG0583	DNA-binding transcription factor activity
FOC38_09525	COG3850	Histidine kinase
FOC38_09535	COG1294	oxidase, subunit
FOC38_09540	COG1271	oxidase subunit
FOC38_09545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC38_09555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC38_09560	COG3138	arginine N-succinyltransferase
FOC38_09570	COG3724	N-succinylarginine dihydrolase activity
FOC38_09590	COG1228	amidohydrolase
FOC38_09600	COG0402	S-adenosylhomocysteine deaminase activity
FOC38_09615	COG1129	ABC transporter
FOC38_09620	COG4211	Belongs to the binding-protein-dependent transport system permease family
FOC38_09625	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC38_09635	COG4942	peptidase
FOC38_09645	COG0012	GTP binding
FOC38_09655	COG0193	aminoacyl-tRNA hydrolase activity
FOC38_09665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC38_09675	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOC38_09680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOC38_09685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC38_09690	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC38_09695	COG3094	Invasion gene expression up-regulator, SirB
FOC38_09700	COG2912	Transglutaminase-like superfamily
FOC38_09710	COG0659	secondary active sulfate transmembrane transporter activity
FOC38_09715	COG3706	GGDEF domain
FOC38_09735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC38_09745	COG3381	protein complex oligomerization
FOC38_09755	COG0477	Major facilitator Superfamily
FOC38_09760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC38_09770	COG0673	inositol 2-dehydrogenase activity
FOC38_09800	COG3102	Protein conserved in bacteria
FOC38_09805	COG3142	Participates in the control of copper homeostasis
FOC38_09820	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FOC38_09825	COG1801	Protein of unknown function DUF72
FOC38_09830	COG1335	isochorismatase
FOC38_09835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOC38_09840	COG0494	nUDIX hydrolase
FOC38_09845	COG0217	transcriptional regulatory protein
FOC38_09855	COG0632	four-way junction helicase activity
FOC38_09860	COG2255	four-way junction helicase activity
FOC38_09865	COG3104	oligopeptide transport
FOC38_09870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC38_09875	COG1121	(ABC) transporter
FOC38_09880	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOC38_09885	COG0739	heme binding
FOC38_09890	COG1560	Kdo2-lipid A biosynthetic process
FOC38_09895	COG0469	pyruvate kinase activity
FOC38_09905	COG1737	Transcriptional regulator
FOC38_09910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC38_09915	COG0800	Aldolase
FOC38_09920	COG2076	Multidrug Resistance protein
FOC38_09925	COG2076	Multidrug Resistance protein
FOC38_09930	COG0251	oxidation-reduction process
FOC38_09935	COG1199	ATP-dependent helicase activity
FOC38_09945	COG3065	identical protein binding
FOC38_09950	COG0318	PFAM AMP-dependent synthetase and ligase
FOC38_09955	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOC38_09960	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOC38_09965	COG2894	cell division
FOC38_09970	COG0850	regulation of cytokinetic process
FOC38_09980	COG3100	YcgL domain-containing protein
FOC38_09985	COG2951	lytic endotransglycosylase activity
FOC38_09990	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC38_09995	COG2983	Belongs to the UPF0260 family
FOC38_10025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC38_10030	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC38_10035	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC38_10040	COG2186	Transcriptional regulator
FOC38_10045	COG2719	SpoVR family
FOC38_10050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC38_10055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC38_10060	COG2814	Major facilitator Superfamily
FOC38_10065	COG2200	EAL domain
FOC38_10065	COG2202	Pas domain
FOC38_10065	COG2199	diguanylate cyclase activity
FOC38_10075	COG2718	Belongs to the UPF0229 family
FOC38_10080	COG2766	serine protein kinase
FOC38_10085	COG3713	MltA-interacting MipA family protein
FOC38_10105	COG3139	Protein of unknown function (DUF1315)
FOC38_10110	COG1335	isochorismatase
FOC38_10115	COG0252	asparaginase activity
FOC38_10120	COG0616	signal peptide processing
FOC38_10125	COG0778	Nitroreductase
FOC38_10135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC38_10145	COG0494	nUDIX hydrolase
FOC38_10150	COG0708	Exodeoxyribonuclease III
FOC38_10155	COG0583	DNA-binding transcription factor activity
FOC38_10190	COG0788	formyltetrahydrofolate deformylase activity
FOC38_10195	COG3012	SEC-C Motif Domain Protein
FOC38_10200	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC38_10205	COG0745	RESPONSE REGULATOR receiver
FOC38_10215	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOC38_10220	COG1435	thymidine kinase activity
FOC38_10225	COG1012	belongs to the aldehyde dehydrogenase family
FOC38_10225	COG1454	alcohol dehydrogenase
FOC38_10230	COG2095	MarC family integral membrane protein
FOC38_10235	COG4166	transmembrane transport
FOC38_10250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC38_10255	COG0444	Belongs to the ABC transporter superfamily
FOC38_10265	COG3099	Belongs to the UPF0263 family
FOC38_10270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC38_10295	COG2350	Protein conserved in bacteria
FOC38_10300	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOC38_10305	COG1607	acyl-coa hydrolase
FOC38_10310	COG2917	probably involved in intracellular septation
FOC38_10330	COG3047	cAMP biosynthetic process
FOC38_10340	COG0159	tryptophan synthase activity
FOC38_10345	COG0133	tryptophan synthase activity
FOC38_10350	COG0134	indole-3-glycerol-phosphate synthase activity
FOC38_10350	COG0135	phosphoribosylanthranilate isomerase activity
FOC38_10360	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC38_10375	COG0613	PHP domain protein
FOC38_10380	COG0009	L-threonylcarbamoyladenylate synthase
FOC38_10385	COG1187	pseudouridine synthase activity
FOC38_10395	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_10400	COG0616	signal peptide processing
FOC38_10410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC38_10415	COG0583	DNA-binding transcription factor activity
FOC38_10425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC38_10430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC38_10435	COG0671	phosphoesterase, PA-phosphatase related
FOC38_10440	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FOC38_10445	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOC38_10465	COG0023	Translation Initiation Factor
FOC38_10475	COG0235	Class ii aldolase
FOC38_10485	COG1349	DNA-binding transcription factor activity
FOC38_10490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC38_10495	COG2879	small protein
FOC38_10500	COG1966	Carbon starvation protein
FOC38_10505	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FOC38_10510	COG0243	molybdopterin cofactor binding
FOC38_10515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC38_10525	COG4659	FMN binding
FOC38_10530	COG4658	electron transport chain
FOC38_10535	COG3708	Transcriptional regulator
FOC38_10535	COG2207	Transcriptional regulator
FOC38_10540	COG4656	Part of a membrane complex involved in electron transport
FOC38_10550	COG4657	Part of a membrane complex involved in electron transport
FOC38_10560	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOC38_10565	COG2274	protein secretion by the type I secretion system
FOC38_10585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC38_10600	COG1879	ABC-type sugar transport system periplasmic component
FOC38_10610	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_10620	COG0673	inositol 2-dehydrogenase activity
FOC38_10625	COG0385	Bile acid
FOC38_10630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOC38_10635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_10635	COG1263	PTS System
FOC38_10635	COG2190	(PTS) system
FOC38_10640	COG4948	Mandelate Racemase Muconate Lactonizing
FOC38_10650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC38_10655	COG1263	PTS System
FOC38_10655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_10660	COG1609	Transcriptional regulator
FOC38_10675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC38_10690	COG1136	(ABC) transporter
FOC38_10705	COG1309	transcriptional regulator
FOC38_10715	COG5339	Protein conserved in bacteria
FOC38_10725	COG0114	fumarate hydratase activity
FOC38_10745	COG2814	Major facilitator Superfamily
FOC38_10750	COG0583	DNA-binding transcription factor activity
FOC38_10755	COG1940	carbohydrate kinase activity
FOC38_10760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOC38_10780	COG1742	UPF0060 membrane protein
FOC38_10790	COG4221	oxidoreductase activity
FOC38_10800	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC38_10825	COG1393	Belongs to the ArsC family
FOC38_10830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC38_10855	COG0625	glutathione transferase activity
FOC38_10860	COG3604	Transcriptional regulator
FOC38_10865	COG0426	domain, Protein
FOC38_10865	COG1773	rubredoxin
FOC38_10870	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC38_10880	COG1522	sequence-specific DNA binding
FOC38_10890	COG4215	(ABC) transporter
FOC38_10905	COG1477	protein flavinylation
FOC38_10910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC38_10920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC38_10950	COG0028	Belongs to the TPP enzyme family
FOC38_10955	COG0440	acetolactate synthase activity
FOC38_10960	COG0251	oxidation-reduction process
FOC38_10965	COG1011	Hydrolase
FOC38_10975	COG0583	DNA-binding transcription factor activity
FOC38_10990	COG0738	Major facilitator superfamily
FOC38_10995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC38_11005	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_11015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOC38_11030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC38_11035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC38_11040	COG0589	response to stress
FOC38_11045	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOC38_11050	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOC38_11065	COG0531	amino acid
FOC38_11075	COG0745	RESPONSE REGULATOR receiver
FOC38_11080	COG2205	protein histidine kinase activity
FOC38_11085	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC38_11095	COG3591	Belongs to the peptidase S1B family
FOC38_11110	COG1643	Atp-dependent helicase
FOC38_11115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC38_11120	COG3784	Protein of unknown function (DUF1318)
FOC38_11130	COG2911	Protein conserved in bacteria
FOC38_11135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC38_11140	COG3042	response to heat
FOC38_11145	COG1285	pathogenesis
FOC38_11155	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC38_11155	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC38_11155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC38_11155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC38_11160	COG0037	tRNA processing
FOC38_11165	COG0598	Magnesium transport protein CorA
FOC38_11170	COG4166	transmembrane transport
FOC38_11175	COG2866	Carboxypeptidase
FOC38_11180	COG4948	Mandelate Racemase Muconate Lactonizing
FOC38_11185	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC38_11205	COG3768	UPF0283 membrane protein
FOC38_11210	COG3106	COG3106 Predicted ATPase
FOC38_11220	COG1983	PspC domain protein
FOC38_11230	COG1842	Phage shock protein A
FOC38_11235	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC38_11250	COG4166	transmembrane transport
FOC38_11255	COG4168	peptide transport system, permease
FOC38_11260	COG4171	peptide transport system, permease
FOC38_11270	COG4172	Belongs to the ABC transporter superfamily
FOC38_11275	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC38_11275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC38_11280	COG0583	DNA-binding transcription factor activity
FOC38_11285	COG3104	oligopeptide transport
FOC38_11305	COG0625	glutathione transferase activity
FOC38_11315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC38_11325	COG3895	Periplasmic Protein
FOC38_11330	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOC38_11335	COG3133	Outer membrane lipoprotein
FOC38_11340	COG1846	Transcriptional regulator
FOC38_11350	COG1566	PFAM secretion protein HlyD family protein
FOC38_11355	COG1289	transmembrane transporter activity
FOC38_11360	COG4989	oxidoreductase activity
FOC38_11365	COG3313	Fe-S protein
FOC38_11370	COG2194	sulfuric ester hydrolase activity
FOC38_11375	COG1309	transcriptional regulator
FOC38_11380	COG1902	pentaerythritol trinitrate reductase activity
FOC38_11385	COG0346	lactoylglutathione lyase activity
FOC38_11390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC38_11395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOC38_11400	COG0791	NLP P60 protein
FOC38_11405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC38_11415	COG1609	Transcriptional regulator
FOC38_11420	COG0583	DNA-binding transcription factor activity
FOC38_11425	COG2814	Major facilitator Superfamily
FOC38_11430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC38_11435	COG0307	riboflavin synthase, alpha
FOC38_11440	COG0534	Mate efflux family protein
FOC38_11470	COG4238	major outer membrane lipoprotein
FOC38_11475	COG1388	LysM domain
FOC38_11475	COG1376	ErfK ybiS ycfS ynhG family protein
FOC38_11480	COG2166	iron-sulfur cluster assembly
FOC38_11490	COG0719	Fe-S assembly protein
FOC38_11495	COG0396	ATPase activity
FOC38_11500	COG0719	Fe-S assembly protein
FOC38_11505	COG0316	Belongs to the HesB IscA family
FOC38_11510	COG2050	protein possibly involved in aromatic compounds catabolism
FOC38_11515	COG0247	lactate metabolic process
FOC38_11515	COG0277	FAD linked oxidase domain protein
FOC38_11520	COG0628	permease
FOC38_11530	COG0574	Belongs to the PEP-utilizing enzyme family
FOC38_11530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC38_11535	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOC38_11540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC38_11555	COG3720	iron ion transport
FOC38_11560	COG4558	Periplasmic binding protein
FOC38_11570	COG0095	Lipoate-protein ligase
FOC38_11575	COG0791	NLP P60 protein
FOC38_11580	COG2076	Multidrug Resistance protein
FOC38_11585	COG2076	Multidrug Resistance protein
FOC38_11590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOC38_11595	COG0726	polysaccharide deacetylase
FOC38_11605	COG0463	Glycosyl transferase, family 2
FOC38_11610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC38_11615	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FOC38_11620	COG0386	Belongs to the glutathione peroxidase family
FOC38_11625	COG4139	cobalamin transport
FOC38_11635	COG0776	regulation of translation
FOC38_11655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOC38_11660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC38_11670	COG4249	Peptidase C14 caspase catalytic subunit p20
FOC38_11675	COG1811	Na channel or pump
FOC38_11680	COG1414	Transcriptional regulator
FOC38_11685	COG1129	ABC transporter
FOC38_11690	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_11710	COG1070	Carbohydrate kinase
FOC38_11715	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOC38_11720	COG3623	hexulose-6-phosphate isomerase
FOC38_11750	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC38_11755	COG1121	(ABC) transporter
FOC38_11760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC38_11765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC38_11775	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC38_11775	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC38_11780	COG1703	isobutyryl-CoA mutase activity
FOC38_11785	COG1024	Enoyl-CoA hydratase
FOC38_11790	COG0427	acetyl-CoA hydrolase
FOC38_11795	COG0583	DNA-binding transcription factor activity
FOC38_11805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC38_11810	COG1917	Cupin 2, conserved barrel domain protein
FOC38_11820	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_11830	COG1175	transmembrane transport
FOC38_11835	COG0395	ABC-type sugar transport system, permease component
FOC38_11840	COG3842	ATPase activity
FOC38_11850	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC38_11855	COG1988	membrane-bound metal-dependent
FOC38_11865	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC38_11875	COG0823	Involved in the tonB-independent uptake of proteins
FOC38_11880	COG2814	Major facilitator Superfamily
FOC38_11885	COG0501	Belongs to the peptidase M48B family
FOC38_11890	COG0793	Belongs to the peptidase S41A family
FOC38_11900	COG1956	GAF domain-containing protein
FOC38_11905	COG2995	paraquat-inducible protein a
FOC38_11910	COG3008	intermembrane lipid transfer
FOC38_11925	COG3706	GGDEF domain
FOC38_11925	COG2203	Gaf domain
FOC38_11925	COG5001	Diguanylate cyclase
FOC38_11925	COG4251	negative regulation of phosphorylation
FOC38_11955	COG0625	glutathione transferase activity
FOC38_11975	COG0697	spore germination
FOC38_11985	COG1187	pseudouridine synthase activity
FOC38_11990	COG0668	transmembrane transport
FOC38_12000	COG0589	response to stress
FOC38_12015	COG1276	copper resistance
FOC38_12020	COG2372	response to copper ion
FOC38_12025	COG1528	Iron-storage protein
FOC38_12040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC38_12045	COG1770	oligopeptidase
FOC38_12060	COG3141	response to X-ray
FOC38_12065	COG0513	Belongs to the DEAD box helicase family
FOC38_12070	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOC38_12075	COG3140	Belongs to the UPF0181 family
FOC38_12085	COG0494	nUDIX hydrolase
FOC38_12090	COG1760	l-serine dehydratase
FOC38_12095	COG1253	flavin adenine dinucleotide binding
FOC38_12100	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_12100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_12105	COG3715	PTS system
FOC38_12110	COG3716	PTS system mannose fructose sorbose family IID component
FOC38_12115	COG4811	Protein of unknown function (DUF986)
FOC38_12120	COG1971	Probably functions as a manganese efflux pump
FOC38_12130	COG3447	MASE1 domain protein
FOC38_12130	COG5001	Diguanylate cyclase
FOC38_12130	COG5002	protein histidine kinase activity
FOC38_12140	COG2226	methyltransferase
FOC38_12145	COG0768	penicillin binding
FOC38_12155	COG1278	Cold shock
FOC38_12170	COG1113	amino acid transport
FOC38_12205	COG2207	Transcriptional regulator
FOC38_12225	COG1132	(ABC) transporter
FOC38_12235	COG3706	GGDEF domain
FOC38_12235	COG4251	negative regulation of phosphorylation
FOC38_12235	COG5001	Diguanylate cyclase
FOC38_12235	COG2203	Gaf domain
FOC38_12250	COG3755	Protein conserved in bacteria
FOC38_12260	COG0697	spore germination
FOC38_12270	COG1733	regulation of RNA biosynthetic process
FOC38_12275	COG0702	epimerase
FOC38_12280	COG2873	o-acetylhomoserine
FOC38_12290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC38_12300	COG0840	transmembrane signaling receptor activity
FOC38_12305	COG3397	chitin binding
FOC38_12325	COG0538	isocitrate dehydrogenase activity
FOC38_12330	COG1187	pseudouridine synthase activity
FOC38_12340	COG0482	sulfurtransferase activity
FOC38_12345	COG2915	High frequency lysogenization protein hflD homolog
FOC38_12350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC38_12360	COG0745	RESPONSE REGULATOR receiver
FOC38_12370	COG2850	peptidyl-arginine hydroxylation
FOC38_12380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC38_12385	COG1940	carbohydrate kinase activity
FOC38_12390	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC38_12400	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC38_12405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC38_12410	COG3134	Outer membrane lipoprotein
FOC38_12415	COG1252	NADH dehydrogenase
FOC38_12420	COG3150	esterase
FOC38_12435	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FOC38_12440	COG5633	Lipoprotein
FOC38_12445	COG0537	adenosine 5'-monophosphoramidase activity
FOC38_12455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_12455	COG1263	PTS System
FOC38_12460	COG0084	hydrolase, TatD family'
FOC38_12465	COG0470	DNA polymerase III
FOC38_12470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOC38_12475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC38_12480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC38_12485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC38_12495	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_12500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC38_12510	COG0416	fatty acid biosynthetic process
FOC38_12515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC38_12520	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC38_12530	COG0564	pseudouridine synthase activity
FOC38_12535	COG1530	ribonuclease E activity
FOC38_12540	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOC38_12545	COG0418	dihydroorotase activity
FOC38_12575	COG0628	permease
FOC38_12610	COG1560	Kdo2-lipid A biosynthetic process
FOC38_12615	COG2259	Doxx family
FOC38_12620	COG2814	Major facilitator Superfamily
FOC38_12625	COG3104	oligopeptide transport
FOC38_12640	COG5645	(Lipo)protein
FOC38_12645	COG2943	transferase activity, transferring hexosyl groups
FOC38_12650	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FOC38_12680	COG3916	Acyl-homoserine-lactone synthase
FOC38_12685	COG2771	luxR family
FOC38_12690	COG2066	Belongs to the glutaminase family
FOC38_12695	COG0531	amino acid
FOC38_12700	COG0076	glutamate decarboxylase activity
FOC38_12720	COG1470	cell adhesion involved in biofilm formation
FOC38_12720	COG1388	LysM domain
FOC38_12735	COG0549	Belongs to the carbamate kinase family
FOC38_12745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC38_12750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC38_12755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOC38_12760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC38_12765	COG3257	ureidoglycine aminohydrolase activity
FOC38_12770	COG1929	Belongs to the glycerate kinase type-1 family
FOC38_12775	COG2233	PERMEase
FOC38_12785	COG1953	Uracil, thiamine, allantoin
FOC38_12790	COG2084	Dehydrogenase
FOC38_12795	COG3622	Belongs to the hyi family
FOC38_12800	COG3960	tartronate-semialdehyde synthase activity
FOC38_12805	COG1414	Transcriptional regulator
FOC38_12815	COG0583	DNA-binding transcription factor activity
FOC38_12820	COG0745	RESPONSE REGULATOR receiver
FOC38_12820	COG3706	GGDEF domain
FOC38_12825	COG4999	Histidine kinase
FOC38_12825	COG3850	Histidine kinase
FOC38_12825	COG3437	response regulator, receiver
FOC38_12825	COG2205	protein histidine kinase activity
FOC38_12850	COG1215	transferase activity, transferring glycosyl groups
FOC38_12860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC38_12865	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC38_12870	COG0745	RESPONSE REGULATOR receiver
FOC38_12880	COG0058	SHG alpha-glucan phosphorylase activity
FOC38_12910	COG3121	Chaperone
FOC38_12925	COG3121	Chaperone
FOC38_12930	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FOC38_12955	COG2920	part of a sulfur-relay system
FOC38_12960	COG1254	Belongs to the acylphosphatase family
FOC38_12970	COG3785	DNA binding
FOC38_12975	COG1832	CoA-binding protein
FOC38_12980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOC38_12990	COG0210	DNA helicase
FOC38_12995	COG3304	Inner membrane component domain
FOC38_13000	COG1289	transmembrane transporter activity
FOC38_13005	COG3070	regulator of competence-specific genes
FOC38_13010	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FOC38_13015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC38_13015	COG2885	chlorophyll binding
FOC38_13020	COG3120	sequence-specific DNA binding
FOC38_13025	COG1067	ATP-dependent peptidase activity
FOC38_13030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC38_13040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC38_13045	COG3130	regulation of translation
FOC38_13050	COG3009	Protein conserved in bacteria
FOC38_13055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC38_13055	COG3008	intermembrane lipid transfer
FOC38_13060	COG2995	paraquat-inducible protein a
FOC38_13065	COG0488	(ABC) transporter
FOC38_13070	COG0116	Belongs to the methyltransferase superfamily
FOC38_13070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC38_13075	COG3217	Mosc domain protein beta barrel domain protein
FOC38_13075	COG0633	Ferredoxin
FOC38_13085	COG0167	dihydroorotate dehydrogenase activity
FOC38_13090	COG0308	aminopeptidase N
FOC38_13095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC38_13100	COG0017	Asparaginyl-tRNA synthetase
FOC38_13110	COG1448	Aminotransferase
FOC38_13115	COG2200	EAL domain
FOC38_13120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC38_13125	COG3108	Peptidase M15
FOC38_13130	COG2989	Protein conserved in bacteria
FOC38_13135	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOC38_13140	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FOC38_13145	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FOC38_13150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC38_13155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC38_13160	COG3173	Aminoglycoside phosphotransferase
FOC38_13175	COG2835	tetraacyldisaccharide 4'-kinase activity
FOC38_13180	COG1278	Cold shock
FOC38_13185	COG1278	Cold shock
FOC38_13190	COG5383	Protein conserved in bacteria
FOC38_13195	COG1663	tetraacyldisaccharide 4'-kinase activity
FOC38_13205	COG0658	competence protein
FOC38_13205	COG2333	competence protein COMEC
FOC38_13210	COG0776	regulation of translation
FOC38_13215	COG0539	negative regulation of cytoplasmic translation
FOC38_13225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOC38_13235	COG0252	asparaginase activity
FOC38_13240	COG1944	ATP diphosphatase activity
FOC38_13245	COG2116	formate transmembrane transporter activity
FOC38_13250	COG1882	Formate acetyltransferase
FOC38_13255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC38_13260	COG2814	Major facilitator Superfamily
FOC38_13265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC38_13270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC38_13275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC38_13280	COG1674	ftsk spoiiie
FOC38_13280	COG3107	peptidoglycan biosynthetic process
FOC38_13290	COG0492	ferredoxin-NADP+ reductase activity
FOC38_13300	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC38_13310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC38_13315	COG0542	response to heat
FOC38_13320	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOC38_13325	COG1278	Cold shock
FOC38_13335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_13340	COG2990	Protein conserved in bacteria
FOC38_13345	COG3593	DNA synthesis involved in DNA repair
FOC38_13350	COG2431	L-lysine efflux transmembrane transporter activity
FOC38_13355	COG1151	hydroxylamine reductase activity
FOC38_13360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC38_13365	COG0028	Belongs to the TPP enzyme family
FOC38_13375	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOC38_13380	COG0702	epimerase
FOC38_13385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC38_13395	COG1126	abc transporter atp-binding protein
FOC38_13400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_13405	COG4215	(ABC) transporter
FOC38_13410	COG4160	amino acid transport
FOC38_13415	COG1414	Transcriptional regulator
FOC38_13420	COG1012	belongs to the aldehyde dehydrogenase family
FOC38_13425	COG1454	alcohol dehydrogenase
FOC38_13430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC38_13435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_13450	COG1177	transmembrane transport
FOC38_13455	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC38_13460	COG3842	ATPase activity
FOC38_13465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC38_13480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC38_13485	COG2985	domain, Protein
FOC38_13485	COG0569	domain protein
FOC38_13495	COG0671	phosphoesterase, PA-phosphatase related
FOC38_13500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC38_13505	COG1349	DNA-binding transcription factor activity
FOC38_13510	COG0814	amino acid
FOC38_13515	COG1760	l-serine dehydratase
FOC38_13520	COG1686	Belongs to the peptidase S11 family
FOC38_13530	COG0626	cystathionine gamma-synthase activity
FOC38_13535	COG2011	ABC-type metal ion transport system permease component
FOC38_13560	COG0625	glutathione transferase activity
FOC38_13565	COG4771	TonB-dependent receptor
FOC38_13570	COG0833	amino acid
FOC38_13575	COG0583	DNA-binding transcription factor activity
FOC38_13580	COG2855	membrane
FOC38_13585	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOC38_13590	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOC38_13590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC38_13590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC38_13595	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC38_13610	COG3005	denitrification pathway
FOC38_13620	COG1349	DNA-binding transcription factor activity
FOC38_13630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_13640	COG3716	PTS system mannose fructose sorbose family IID component
FOC38_13645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_13650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC38_13655	COG2222	sugar isomerase
FOC38_13680	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC38_13685	COG1312	Catalyzes the dehydration of D-mannonate
FOC38_13695	COG0246	Mannitol dehydrogenase
FOC38_13700	COG2186	Transcriptional regulator
FOC38_13705	COG0523	cobalamin synthesis protein
FOC38_13710	COG0671	phosphoesterase, PA-phosphatase related
FOC38_13715	COG0791	NLP P60 protein
FOC38_13720	COG2200	EAL domain
FOC38_13725	COG4166	transmembrane transport
FOC38_13730	COG4174	ABC transporter (Permease)
FOC38_13735	COG4239	(ABC) transporter, permease
FOC38_13740	COG4172	Belongs to the ABC transporter superfamily
FOC38_13755	COG2814	Major facilitator Superfamily
FOC38_13760	COG1187	pseudouridine synthase activity
FOC38_13765	COG1061	Type III restriction enzyme res subunit
FOC38_13775	COG3081	Nucleoid-associated protein
FOC38_13780	COG3082	Protein of unknown function (DUF1414)
FOC38_13815	COG3338	carbonate dehydratase activity
FOC38_13820	COG2723	6-phospho-beta-galactosidase activity
FOC38_13825	COG2190	(PTS) system
FOC38_13825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_13825	COG1263	PTS System
FOC38_13875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC38_13890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC38_13890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC38_13895	COG0583	DNA-binding transcription factor activity
FOC38_13900	COG1648	precorrin-2 dehydrogenase activity
FOC38_13900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC38_13910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC38_13920	COG4865	methylaspartate mutase activity
FOC38_13925	COG3799	methylaspartate ammonia-lyase activity
FOC38_13940	COG1301	dicarboxylic acid transport
FOC38_13955	COG3188	usher protein
FOC38_14000	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC38_14015	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC38_14035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC38_14040	COG2223	nitrite transmembrane transporter activity
FOC38_14045	COG0642	Histidine kinase
FOC38_14045	COG2198	Histidine kinase
FOC38_14055	COG2205	protein histidine kinase activity
FOC38_14055	COG0784	Response regulator, receiver
FOC38_14065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC38_14070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC38_14080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC38_14085	COG4574	serine-type endopeptidase inhibitor activity
FOC38_14120	COG0814	amino acid
FOC38_14140	COG1441	menaquinone biosynthetic process
FOC38_14145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC38_14155	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC38_14160	COG1169	isochorismate synthase
FOC38_14165	COG4575	ribosome binding
FOC38_14170	COG0129	dihydroxy-acid dehydratase activity
FOC38_14175	COG4702	Belongs to the UPF0303 family
FOC38_14185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC38_14190	COG1609	Transcriptional regulator
FOC38_14195	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_14200	COG3265	gluconokinase activity
FOC38_14205	COG2731	YhcH YjgK YiaL family protein
FOC38_14220	COG1007	ATP synthesis coupled electron transport
FOC38_14225	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC38_14230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC38_14235	COG0713	ATP synthesis coupled electron transport
FOC38_14240	COG0839	Belongs to the complex I subunit 6 family
FOC38_14245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC38_14250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOC38_14255	COG1034	ATP synthesis coupled electron transport
FOC38_14265	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FOC38_14270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC38_14270	COG0649	NAD binding
FOC38_14275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC38_14285	COG0583	DNA-binding transcription factor activity
FOC38_14295	COG0436	Aminotransferase
FOC38_14305	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOC38_14310	COG0490	domain, Protein
FOC38_14310	COG0471	metal ion transport
FOC38_14315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC38_14325	COG3092	negative regulation of chromosome organization
FOC38_14335	COG0857	belongs to the CobB CobQ family
FOC38_14335	COG0280	phosphate acetyltransferase
FOC38_14340	COG1609	Transcriptional regulator
FOC38_14345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_14355	COG3037	sugar-specific permease SgaT UlaA
FOC38_14360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOC38_14365	COG0622	Phosphoesterase
FOC38_14375	COG1090	epimerase
FOC38_14385	COG4598	ABC transporter
FOC38_14390	COG4160	amino acid transport
FOC38_14395	COG4215	(ABC) transporter
FOC38_14400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_14405	COG0163	prenyltransferase activity
FOC38_14410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC38_14415	COG1286	toxin biosynthetic process
FOC38_14420	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOC38_14425	COG0285	dihydrofolate synthase activity
FOC38_14435	COG0586	Pfam SNARE associated Golgi protein
FOC38_14445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC38_14470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC38_14475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC38_14500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC38_14510	COG1794	racemase activity, acting on amino acids and derivatives
FOC38_14515	COG0745	RESPONSE REGULATOR receiver
FOC38_14515	COG3706	GGDEF domain
FOC38_14520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC38_14525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC38_14525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOC38_14535	COG3101	peptidyl-lysine hydroxylation
FOC38_14540	COG0730	response to heat
FOC38_14550	COG5301	cellulose 1,4-beta-cellobiosidase activity
FOC38_14600	COG0741	lytic transglycosylase activity
FOC38_14600	COG1196	nuclear chromosome segregation
FOC38_14600	COG0739	heme binding
FOC38_14710	COG3772	lysozyme
FOC38_14730	COG0305	Participates in initiation and elongation during chromosome replication
FOC38_14735	COG1484	DNA-dependent DNA replication
FOC38_14750	COG4197	protein conserved in bacteria, prophage-related
FOC38_14860	COG0582	viral genome integration into host DNA
FOC38_14865	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FOC38_14870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC38_14875	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC38_14880	COG2840	Smr protein MutS2
FOC38_14885	COG2062	phosphohistidine phosphatase, SixA
FOC38_14890	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC38_14890	COG1024	Enoyl-CoA hydratase
FOC38_14895	COG0183	Belongs to the thiolase family
FOC38_14900	COG3691	Protein conserved in bacteria
FOC38_14915	COG4235	cytochrome complex assembly
FOC38_14915	COG3088	subunit of a heme lyase
FOC38_14920	COG4235	cytochrome complex assembly
FOC38_14920	COG3088	subunit of a heme lyase
FOC38_14925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC38_14930	COG1138	Cytochrome C-type biogenesis protein
FOC38_14935	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOC38_14940	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC38_14945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC38_14950	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC38_14965	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC38_14975	COG0582	viral genome integration into host DNA
FOC38_15075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC38_15130	COG1695	Transcriptional regulator
FOC38_15140	COG2723	6-phospho-beta-galactosidase activity
FOC38_15145	COG1263	PTS System
FOC38_15145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_15150	COG1609	Transcriptional regulator
FOC38_15160	COG2353	YceI-like domain
FOC38_15165	COG3038	cytochrome b561
FOC38_15175	COG0626	cystathionine gamma-synthase activity
FOC38_15195	COG1127	ABC transporter
FOC38_15200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC38_15220	COG0531	amino acid
FOC38_15225	COG2951	lytic endotransglycosylase activity
FOC38_15255	COG2723	6-phospho-beta-galactosidase activity
FOC38_15270	COG0243	molybdopterin cofactor binding
FOC38_15275	COG0437	4 iron, 4 sulfur cluster binding
FOC38_15280	COG3302	dmso reductase anchor subunit
FOC38_15285	COG3381	protein complex oligomerization
FOC38_15295	COG1598	PFAM Uncharacterised protein family UPF0150
FOC38_15305	COG3038	cytochrome b561
FOC38_15310	COG0436	Aminotransferase
FOC38_15325	COG3275	phosphorelay sensor kinase activity
FOC38_15330	COG3279	Response regulator of the LytR AlgR family
FOC38_15335	COG2223	nitrite transmembrane transporter activity
FOC38_15340	COG0837	glucose binding
FOC38_15355	COG0667	Aldo Keto reductase
FOC38_15365	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC38_15370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC38_15405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC38_15430	COG3530	Putative quorum-sensing-regulated virulence factor
FOC38_15435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC38_15445	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FOC38_15450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC38_15455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_15465	COG2190	(PTS) system
FOC38_15470	COG2205	protein histidine kinase activity
FOC38_15475	COG0745	RESPONSE REGULATOR receiver
FOC38_15480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_15550	COG4208	sulfate ABC transporter
FOC38_15555	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOC38_15560	COG4150	thiosulfate binding
FOC38_15565	COG2837	iron assimilation
FOC38_15575	COG3111	PFAM Bacterial OB fold (BOF) protein
FOC38_15655	COG2826	transposase and inactivated derivatives, IS30 family
FOC38_15685	COG0456	acetyltransferase
FOC38_15690	COG0408	coproporphyrinogen oxidase activity
FOC38_15695	COG1671	Belongs to the UPF0178 family
FOC38_15720	COG3005	denitrification pathway
FOC38_15725	COG3043	anaerobic respiration
FOC38_15730	COG0243	molybdopterin cofactor binding
FOC38_15735	COG3062	negative regulation of establishment of protein localization
FOC38_15740	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC38_15740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC38_15745	COG2197	response regulator
FOC38_15755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC38_15800	COG1393	Belongs to the ArsC family
FOC38_15805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC38_15810	COG1876	peptidase activity
FOC38_15820	COG0400	carboxylic ester hydrolase activity
FOC38_15830	COG1444	tRNA N-acetyltransferase activity
FOC38_15840	COG2321	neutral zinc metallopeptidase
FOC38_15850	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOC38_15855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC38_15860	COG2716	regulation of RNA biosynthetic process
FOC38_15865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC38_15870	COG0628	permease
FOC38_15875	COG4783	chaperone-mediated protein folding
FOC38_15880	COG1393	Belongs to the ArsC family
FOC38_15885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC38_15890	COG2233	PERMEase
FOC38_15900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC38_15905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC38_15910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC38_15925	COG0581	inorganic phosphate transmembrane transporter activity
FOC38_15930	COG0573	inorganic phosphate transmembrane transporter activity
FOC38_15935	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC38_15940	COG0248	Ppx GppA phosphatase
FOC38_15950	COG2239	Acts as a magnesium transporter
FOC38_15955	COG5002	protein histidine kinase activity
FOC38_15955	COG5001	Diguanylate cyclase
FOC38_15955	COG3447	MASE1 domain protein
FOC38_15960	COG0443	Heat shock 70 kDa protein
FOC38_15965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_15975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC38_15980	COG2205	protein histidine kinase activity
FOC38_15985	COG0745	RESPONSE REGULATOR receiver
FOC38_15990	COG3422	double-strand break repair
FOC38_16000	COG1597	lipid kinase activity
FOC38_16005	COG3730	PTS system glucitol sorbitol-specific
FOC38_16020	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_16025	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_16030	COG1349	DNA-binding transcription factor activity
FOC38_16050	COG0351	phosphomethylpyrimidine kinase
FOC38_16070	COG0519	Catalyzes the synthesis of GMP from XMP
FOC38_16070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC38_16075	COG0517	IMP dehydrogenase activity
FOC38_16075	COG0516	GMP reductase activity
FOC38_16085	COG1645	bacterial-type flagellum-dependent swarming motility
FOC38_16100	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC38_16105	COG2976	Protein conserved in bacteria
FOC38_16120	COG1426	Protein conserved in bacteria
FOC38_16130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOC38_16145	COG4953	penicillin-binding protein 1C
FOC38_16150	COG2373	Large extracellular alpha-helical protein
FOC38_16155	COG3468	outer membrane autotransporter barrel domain protein
FOC38_16170	COG2975	iron-sulfur cluster assembly
FOC38_16175	COG0633	Ferredoxin
FOC38_16180	COG0443	Heat shock 70 kDa protein
FOC38_16185	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOC38_16195	COG0822	iron-sulfur transferase activity
FOC38_16205	COG1959	2 iron, 2 sulfur cluster binding
FOC38_16210	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOC38_16215	COG0483	inositol monophosphate 1-phosphatase activity
FOC38_16220	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FOC38_16225	COG3683	transport system, periplasmic component
FOC38_16230	COG3711	transcriptional antiterminator
FOC38_16235	COG2814	Major facilitator Superfamily
FOC38_16245	COG1017	nitric oxide dioxygenase activity
FOC38_16245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC38_16250	COG2188	Transcriptional regulator
FOC38_16260	COG3457	Alanine racemase
FOC38_16265	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FOC38_16280	COG0347	Belongs to the P(II) protein family
FOC38_16285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOC38_16285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC38_16290	COG2204	response regulator
FOC38_16295	COG3170	Tfp pilus assembly protein FimV
FOC38_16300	COG2205	protein histidine kinase activity
FOC38_16315	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC38_16320	COG0590	tRNA wobble adenosine to inosine editing
FOC38_16330	COG0560	Phosphoserine phosphatase
FOC38_16345	COG1737	Transcriptional regulator
FOC38_16350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC38_16355	COG0736	holo-[acyl-carrier-protein] synthase activity
FOC38_16360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOC38_16365	COG1381	Involved in DNA repair and RecF pathway recombination
FOC38_16370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC38_16380	COG0681	Belongs to the peptidase S26 family
FOC38_16385	COG0481	GTPase activity
FOC38_16395	COG3086	response to oxidative stress
FOC38_16400	COG3026	antisigma factor binding
FOC38_16405	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FOC38_16415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC38_16420	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC38_16425	COG0513	Belongs to the DEAD box helicase family
FOC38_16440	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FOC38_16445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC38_16450	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC38_16455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC38_16460	COG0497	DNA recombination
FOC38_16465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC38_16475	COG2867	negative regulation of translational initiation
FOC38_16480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOC38_16490	COG0582	viral genome integration into host DNA
FOC38_16525	COG3394	polysaccharide catabolic process
FOC38_16530	COG1917	Cupin 2, conserved barrel domain protein
FOC38_16530	COG2169	Transcriptional regulator
FOC38_16535	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC38_16540	COG2723	6-phospho-beta-galactosidase activity
FOC38_16545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC38_16550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC38_16555	COG2133	pyrroloquinoline quinone binding
FOC38_16560	COG0667	Aldo Keto reductase
FOC38_16570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC38_16575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC38_16585	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FOC38_16590	COG4413	Urea transporter
FOC38_16600	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC38_16605	COG0830	nickel cation binding
FOC38_16610	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FOC38_16615	COG0804	urea catabolic process
FOC38_16630	COG1124	(ABC) transporter
FOC38_16640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC38_16645	COG0601	transmembrane transport
FOC38_16675	COG1278	Cold shock
FOC38_16695	COG2207	Transcriptional regulator
FOC38_16695	COG3708	Transcriptional regulator
FOC38_16710	COG4575	ribosome binding
FOC38_16720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC38_16725	COG1780	Probably involved in ribonucleotide reductase function
FOC38_16735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC38_16745	COG4176	ABC-type proline glycine betaine transport system permease component
FOC38_16750	COG2113	Glycine betaine
FOC38_16780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC38_16790	COG2226	methyltransferase
FOC38_16795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC38_16800	COG0741	lytic transglycosylase activity
FOC38_16800	COG1388	LysM domain
FOC38_16805	COG3021	interspecies interaction between organisms
FOC38_16810	COG2814	Major facilitator Superfamily
FOC38_16815	COG0583	DNA-binding transcription factor activity
FOC38_16830	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_16870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC38_16885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC38_16945	COG0542	response to heat
FOC38_16955	COG0564	pseudouridine synthase activity
FOC38_16960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC38_16965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC38_16970	COG0077	Prephenate dehydratase
FOC38_16970	COG1605	Chorismate mutase
FOC38_16975	COG0287	Prephenate dehydrogenase
FOC38_16975	COG1605	Chorismate mutase
FOC38_16980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC38_16985	COG3279	Response regulator of the LytR AlgR family
FOC38_16990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC38_16995	COG3137	Salt-induced outer membrane protein
FOC38_17000	COG0335	large ribosomal subunit rRNA binding
FOC38_17005	COG0336	Belongs to the RNA methyltransferase TrmD family
FOC38_17015	COG0228	four-way junction DNA binding
FOC38_17020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC38_17025	COG4137	Cytochrome C assembly protein
FOC38_17030	COG4536	flavin adenine dinucleotide binding
FOC38_17035	COG1854	S-ribosylhomocysteine lyase activity
FOC38_17040	COG2918	glutathione biosynthetic process
FOC38_17045	COG1238	metal cluster binding
FOC38_17050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC38_17085	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOC38_17090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC38_17095	COG2137	regulation of response to DNA damage stimulus
FOC38_17100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOC38_17125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC38_17130	COG3958	Transketolase
FOC38_17135	COG3959	Transketolase, thiamine diphosphate binding domain
FOC38_17140	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_17145	COG1129	ABC transporter
FOC38_17155	COG1609	Transcriptional regulator
FOC38_17170	COG3381	protein complex oligomerization
FOC38_17175	COG3302	dmso reductase anchor subunit
FOC38_17180	COG0437	4 iron, 4 sulfur cluster binding
FOC38_17185	COG0243	molybdopterin cofactor binding
FOC38_17190	COG1454	alcohol dehydrogenase
FOC38_17195	COG0235	Class ii aldolase
FOC38_17200	COG0738	Major facilitator superfamily
FOC38_17210	COG1070	Carbohydrate kinase
FOC38_17220	COG1349	DNA-binding transcription factor activity
FOC38_17225	COG0235	Class ii aldolase
FOC38_17230	COG1349	DNA-binding transcription factor activity
FOC38_17245	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_17250	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_17255	COG3623	hexulose-6-phosphate isomerase
FOC38_17260	COG1070	Carbohydrate kinase
FOC38_17265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC38_17265	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC38_17275	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC38_17280	COG4177	L-phenylalanine transmembrane transporter activity
FOC38_17285	COG1137	ATPase activity
FOC38_17290	COG0410	ABC transporter
FOC38_17345	COG0640	Transcriptional regulator
FOC38_17350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC38_17355	COG3158	transport of potassium into the cell
FOC38_17360	COG3048	D-serine ammonia-lyase activity
FOC38_17365	COG2610	gluconate transmembrane transporter activity
FOC38_17370	COG0583	DNA-binding transcription factor activity
FOC38_17375	COG4608	Belongs to the ABC transporter superfamily
FOC38_17385	COG0601	transmembrane transport
FOC38_17395	COG4948	Mandelate Racemase Muconate Lactonizing
FOC38_17400	COG1028	Short-chain dehydrogenase reductase Sdr
FOC38_17420	COG1538	Outer membrane efflux protein
FOC38_17425	COG0577	efflux transmembrane transporter activity
FOC38_17425	COG1136	(ABC) transporter
FOC38_17430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_17445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC38_17460	COG3539	Fimbrial protein
FOC38_17465	COG3539	Fimbrial protein
FOC38_17480	COG3121	Chaperone
FOC38_17485	COG3188	usher protein
FOC38_17510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC38_17515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC38_17520	COG1388	LysM domain
FOC38_17520	COG4942	peptidase
FOC38_17525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOC38_17530	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOC38_17535	COG0585	pseudouridine synthase activity
FOC38_17540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOC38_17550	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOC38_17560	COG0765	amino acid transport
FOC38_17575	COG0529	Catalyzes the synthesis of activated sulfate
FOC38_17580	COG2895	sulfate adenylyltransferase (ATP) activity
FOC38_17585	COG0175	sulfate reduction
FOC38_17590	COG1648	precorrin-2 dehydrogenase activity
FOC38_17590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC38_17595	COG2234	aminopeptidase activity
FOC38_17610	COG0175	sulfate reduction
FOC38_17615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC38_17620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOC38_17625	COG0720	synthase
FOC38_17630	COG0602	queuosine metabolic process
FOC38_17640	COG0148	phosphopyruvate hydratase activity
FOC38_17645	COG0504	CTP synthase activity
FOC38_17650	COG3956	TIGRFAM MazG family protein
FOC38_17655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC38_17660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC38_17670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC38_17675	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOC38_17680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC38_17690	COG2860	membrane
FOC38_17695	COG0316	Belongs to the HesB IscA family
FOC38_17705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOC38_17715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC38_17720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC38_17725	COG1120	ATPase activity
FOC38_17730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC38_17735	COG1643	Atp-dependent helicase
FOC38_17740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC38_17745	COG1489	DNA binding
FOC38_17750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC38_17760	COG0617	tRNA 3'-terminal CCA addition
FOC38_17765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC38_17770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC38_17775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC38_17785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOC38_17790	COG0726	polysaccharide deacetylase
FOC38_17795	COG0842	Transport permease protein
FOC38_17800	COG1131	(ABC) transporter
FOC38_17805	COG0288	reversible hydration of carbon dioxide
FOC38_17810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOC38_17815	COG2132	Multicopper oxidase
FOC38_17825	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC38_17830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC38_17840	COG3112	Uncharacterised protein family (UPF0231)
FOC38_17845	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOC38_17860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC38_17865	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC38_17870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOC38_17875	COG2186	Transcriptional regulator
FOC38_17880	COG1113	amino acid transport
FOC38_17885	COG3725	Membrane protein required for beta-lactamase induction
FOC38_17900	COG4969	Belongs to the N-Me-Phe pilin family
FOC38_17905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC38_17910	COG1459	type II secretion system
FOC38_17915	COG0516	GMP reductase activity
FOC38_17920	COG0237	dephospho-CoA kinase activity
FOC38_17930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOC38_17935	COG0494	nUDIX hydrolase
FOC38_17940	COG0653	protein targeting
FOC38_17960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC38_17965	COG0849	cell division
FOC38_17970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC38_17980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC38_17985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC38_17990	COG0772	Belongs to the SEDS family
FOC38_18000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC38_18005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC38_18010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC38_18015	COG0768	penicillin binding
FOC38_18020	COG3116	cell division
FOC38_18025	COG0275	rRNA processing
FOC38_18040	COG1609	Transcriptional regulator
FOC38_18050	COG0028	Belongs to the TPP enzyme family
FOC38_18055	COG1022	Amp-dependent synthetase and ligase
FOC38_18060	COG0583	DNA-binding transcription factor activity
FOC38_18070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC38_18075	COG0473	3-isopropylmalate dehydrogenase activity
FOC38_18080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC38_18095	COG3033	Beta-eliminating lyase
FOC38_18100	COG0814	amino acid
FOC38_18105	COG2814	Major facilitator Superfamily
FOC38_18115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC38_18120	COG4533	DNA binding
FOC38_18125	COG4143	(ABC) transporter
FOC38_18130	COG1178	ABC-type Fe3 transport system permease component
FOC38_18140	COG0586	Pfam SNARE associated Golgi protein
FOC38_18150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC38_18155	COG0564	pseudouridine synthase activity
FOC38_18160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOC38_18165	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC38_18170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC38_18180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC38_18185	COG2967	ApaG domain
FOC38_18190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC38_18195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC38_18205	COG2966	Psort location CytoplasmicMembrane, score
FOC38_18210	COG1280	lysine exporter protein (LysE YggA)
FOC38_18215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC38_18220	COG0505	Belongs to the CarA family
FOC38_18230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOC38_18235	COG1047	Peptidyl-prolyl cis-trans
FOC38_18240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOC38_18245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC38_18250	COG0196	riboflavin kinase activity
FOC38_18265	COG0583	DNA-binding transcription factor activity
FOC38_18270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC38_18275	COG0484	heat shock protein binding
FOC38_18285	COG1584	GPR1 FUN34 yaaH family protein
FOC38_18300	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC38_18305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC38_18310	COG3022	response to hydroperoxide
FOC38_18320	COG0083	homoserine kinase activity
FOC38_18335	COG0745	RESPONSE REGULATOR receiver
FOC38_18340	COG3045	CreA protein
FOC38_18345	COG3708	Transcriptional regulator
FOC38_18345	COG2207	Transcriptional regulator
FOC38_18355	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC38_18360	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FOC38_18365	COG0741	lytic transglycosylase activity
FOC38_18370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC38_18380	COG2199	diguanylate cyclase activity
FOC38_18385	COG2885	chlorophyll binding
FOC38_18390	COG0488	(ABC) transporter
FOC38_18425	COG1454	alcohol dehydrogenase
FOC38_18440	COG0604	alcohol dehydrogenase
FOC38_18455	COG0560	Phosphoserine phosphatase
FOC38_18460	COG3726	membrane protein affecting hemolysin expression
FOC38_18465	COG3550	peptidyl-serine autophosphorylation
FOC38_18475	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOC38_18480	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC38_18485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC38_18490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC38_18495	COG0084	hydrolase, TatD family'
FOC38_18500	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC38_18510	COG2823	Periplasmic or secreted lipoprotein
FOC38_18515	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOC38_18520	COG0456	acetyltransferase
FOC38_18525	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FOC38_18535	COG0667	Aldo Keto reductase
FOC38_18565	COG3706	GGDEF domain
FOC38_18625	COG2192	nodulation
FOC38_18635	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOC38_18635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_18635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC38_18640	COG1461	Dihydroxyacetone kinase
FOC38_18645	COG2376	Dihydroxyacetone kinase
FOC38_18655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC38_18660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC38_18665	COG2235	arginine
FOC38_18680	COG0859	PFAM glycosyl transferase family 9
FOC38_18690	COG1070	Carbohydrate kinase
FOC38_18695	COG2390	Transcriptional regulator
FOC38_18700	COG1129	ABC transporter
FOC38_18705	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_18710	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_18715	COG1879	ABC-type sugar transport system periplasmic component
FOC38_18720	COG1830	Aldolase
FOC38_18730	COG0642	Histidine kinase
FOC38_18755	COG3272	Protein of unknown function (DUF1722)
FOC38_18775	COG3423	Transcriptional regulator
FOC38_18780	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC38_18895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC38_18935	COG0582	viral genome integration into host DNA
FOC38_18985	COG0795	lipopolysaccharide-transporting ATPase activity
FOC38_18990	COG0795	lipopolysaccharide-transporting ATPase activity
FOC38_18995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOC38_19000	COG2927	DNA polymerase III (CHI subunit)
FOC38_19015	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FOC38_19025	COG2731	YhcH YjgK YiaL family protein
FOC38_19035	COG0601	transmembrane transport
FOC38_19045	COG0444	Belongs to the ABC transporter superfamily
FOC38_19050	COG4608	Belongs to the ABC transporter superfamily
FOC38_19055	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC38_19060	COG0583	DNA-binding transcription factor activity
FOC38_19075	COG2188	Transcriptional regulator
FOC38_19080	COG3624	Phosphonate C-P lyase system protein PhnG
FOC38_19085	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FOC38_19090	COG3626	phosphonate metabolism
FOC38_19095	COG3627	carbon phosphorus lyase activity
FOC38_19100	COG4107	phosphonate C-P lyase system protein PhnK
FOC38_19105	COG4778	phosphonate C-P lyase system protein PhnL
FOC38_19110	COG3454	Phosphonate metabolism
FOC38_19115	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FOC38_19120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC38_19125	COG0702	epimerase
FOC38_19130	COG3787	Belongs to the UPF0306 family
FOC38_19140	COG1982	Orn Lys Arg decarboxylase major
FOC38_19145	COG0531	amino acid
FOC38_19150	COG2827	Endonuclease containing a URI domain
FOC38_19155	COG3153	acetyltransferase
FOC38_19175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC38_19180	COG0513	Belongs to the DEAD box helicase family
FOC38_19195	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC38_19205	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC38_19210	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOC38_19220	COG0195	Participates in both transcription termination and antitermination
FOC38_19240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC38_19250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC38_19255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC38_19260	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOC38_19265	COG1534	Rna-binding protein
FOC38_19270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC38_19275	COG2027	D-alanyl-D-alanine carboxypeptidase
FOC38_19280	COG0745	RESPONSE REGULATOR receiver
FOC38_19285	COG0642	Histidine kinase
FOC38_19290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC38_19295	COG0697	spore germination
FOC38_19310	COG0142	geranyltranstransferase activity
FOC38_19325	COG3423	Transcriptional regulator
FOC38_19350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC38_19355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOC38_19360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOC38_19365	COG2105	PFAM AIG2 family protein
FOC38_19370	COG2911	Protein conserved in bacteria
FOC38_19375	COG0729	surface antigen
FOC38_19380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC38_19385	COG1253	flavin adenine dinucleotide binding
FOC38_19395	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOC38_19400	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOC38_19405	COG0737	Belongs to the 5'-nucleotidase family
FOC38_19415	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC38_19420	COG3061	Opacity-associated protein A
FOC38_19430	COG0359	binds to the 23S rRNA
FOC38_19435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC38_19440	COG2965	DNA replication, synthesis of RNA primer
FOC38_19445	COG0360	Binds together with S18 to 16S ribosomal RNA
FOC38_19460	COG1073	alpha beta
FOC38_19465	COG3650	response to hydrogen peroxide
FOC38_19470	COG1960	acyl-CoA dehydrogenase activity
FOC38_19475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC38_19480	COG0557	exoribonuclease II activity
FOC38_19485	COG1959	2 iron, 2 sulfur cluster binding
FOC38_19490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOC38_19495	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOC38_19500	COG0330	HflC and HflK could
FOC38_19505	COG0330	HflC and HflK could
FOC38_19510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC38_19520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC38_19525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOC38_19530	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC38_19535	COG0802	atpase or kinase
FOC38_19540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOC38_19540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC38_19545	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC38_19565	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOC38_19570	COG1162	GTPase activity
FOC38_19575	COG0688	phosphatidylethanolamine metabolic process
FOC38_19580	COG1511	domain protein
FOC38_19580	COG3264	Mechanosensitive ion channel
FOC38_19585	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOC38_19590	COG1053	succinate dehydrogenase
FOC38_19595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC38_19600	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOC38_19605	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOC38_19615	COG2076	Multidrug Resistance protein
FOC38_19640	COG0459	protein refolding
FOC38_19645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOC38_19660	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC38_19670	COG4232	protein-disulfide reductase activity
FOC38_19675	COG3383	formate dehydrogenase (NAD+) activity
FOC38_19680	COG0493	'glutamate synthase
FOC38_19680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC38_19685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC38_19685	COG0493	'glutamate synthase
FOC38_19690	COG2271	Major facilitator Superfamily
FOC38_19695	COG2721	sulfolactate sulfo-lyase activity
FOC38_19700	COG3835	regulator
FOC38_19705	COG1929	Belongs to the glycerate kinase type-1 family
FOC38_19710	COG2084	Dehydrogenase
FOC38_19720	COG1309	transcriptional regulator
FOC38_19730	COG3876	Protein conserved in bacteria
FOC38_19740	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC38_19750	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOC38_19755	COG1263	PTS System
FOC38_19755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC38_19770	COG0840	transmembrane signaling receptor activity
FOC38_19775	COG1882	Formate acetyltransferase
FOC38_19780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC38_19785	COG0814	amino acid
FOC38_19795	COG0488	(ABC) transporter
FOC38_19810	COG3720	iron ion transport
FOC38_19815	COG4558	Periplasmic binding protein
FOC38_19820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC38_19825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOC38_19835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC38_19845	COG4774	siderophore transport
FOC38_19850	COG1511	domain protein
FOC38_19850	COG3264	Mechanosensitive ion channel
FOC38_20005	COG5002	protein histidine kinase activity
FOC38_20005	COG0784	Response regulator, receiver
FOC38_20005	COG2205	protein histidine kinase activity
FOC38_20015	COG1301	dicarboxylic acid transport
FOC38_20020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC38_20025	COG3162	membrane
FOC38_20030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC38_20070	COG0138	bifunctional purine biosynthesis protein purh
FOC38_20075	COG0151	Belongs to the GarS family
FOC38_20090	COG3068	Protein conserved in bacteria
FOC38_20095	COG1515	deoxyribonuclease V activity
FOC38_20100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC38_20105	COG2816	NAD+ diphosphatase activity
FOC38_20110	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FOC38_20115	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOC38_20125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC38_20130	COG2104	thiamine diphosphate biosynthetic process
FOC38_20135	COG2022	thiamine diphosphate biosynthetic process
FOC38_20145	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC38_20150	COG0085	RNA polymerase activity
FOC38_20155	COG0222	ribosome binding
FOC38_20160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOC38_20165	COG0081	regulation of translation
FOC38_20170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC38_20175	COG0250	Participates in transcription elongation, termination and antitermination
FOC38_20180	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC38_20220	COG1072	(Pantothenic acid kinase))
FOC38_20225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOC38_20225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOC38_20265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC38_20270	COG1739	Uncharacterized protein family UPF0029
FOC38_20280	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC38_20280	COG1024	Enoyl-CoA hydratase
FOC38_20285	COG0183	Belongs to the thiolase family
FOC38_20295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOC38_20315	COG0805	protein transport
FOC38_20320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC38_20325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC38_20330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC38_20335	COG3165	ubiquinone biosynthetic process from chorismate
FOC38_20340	COG2226	methyltransferase
FOC38_20345	COG1322	Protein conserved in bacteria
FOC38_20350	COG0586	Pfam SNARE associated Golgi protein
FOC38_20355	COG1966	Carbon starvation protein
FOC38_20365	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOC38_20370	COG0412	Dienelactone hydrolase
FOC38_20375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOC38_20380	COG0583	DNA-binding transcription factor activity
FOC38_20390	COG0679	Auxin Efflux Carrier
FOC38_20395	COG0584	glycerophosphoryl diester phosphodiesterase
FOC38_20400	COG3842	ATPase activity
FOC38_20405	COG0395	ABC-type sugar transport system, permease component
FOC38_20410	COG1175	transmembrane transport
FOC38_20415	COG1653	transport
FOC38_20450	COG0410	ABC transporter
FOC38_20455	COG0411	ABC transporter
FOC38_20460	COG4177	L-phenylalanine transmembrane transporter activity
FOC38_20465	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC38_20470	COG0683	leucine binding
FOC38_20475	COG0456	acetyltransferase
FOC38_20485	COG2177	Part of the ABC transporter FtsEX involved in
FOC38_20490	COG2884	Cell division ATP-binding protein ftsE
FOC38_20495	COG0552	protein localization to endoplasmic reticulum
FOC38_20500	COG0742	ribosomal rna small subunit methyltransferase
FOC38_20505	COG3776	membrane
FOC38_20520	COG3714	YhhN family
FOC38_20525	COG2217	Heavy metal translocating P-type atpase
FOC38_20530	COG0425	Belongs to the sulfur carrier protein TusA family
FOC38_20535	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOC38_20545	COG0247	lactate metabolic process
FOC38_20550	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC38_20555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC38_20565	COG2271	Major facilitator Superfamily
FOC38_20570	COG0584	glycerophosphoryl diester phosphodiesterase
FOC38_20575	COG0561	phosphatase activity
FOC38_20580	COG2267	carboxylic ester hydrolase activity
FOC38_20585	COG1280	lysine exporter protein (LysE YggA)
FOC38_20590	COG1280	lysine exporter protein (LysE YggA)
FOC38_20595	COG0514	ATP-dependent DNA helicase (RecQ)
FOC38_20600	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FOC38_20605	COG2050	protein possibly involved in aromatic compounds catabolism
FOC38_20615	COG0598	Magnesium transport protein CorA
FOC38_20625	COG5564	TIM-barrel signal transduction protein
FOC38_20630	COG5441	Belongs to the UPF0261 family
FOC38_20640	COG0210	DNA helicase
FOC38_20645	COG1011	Hydrolase
FOC38_20650	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC38_20655	COG3159	Protein conserved in bacteria
FOC38_20660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOC38_20665	COG5567	small periplasmic lipoprotein
FOC38_20675	COG3072	Adenylate cyclase
FOC38_20680	COG0181	hydroxymethylbilane synthase activity
FOC38_20685	COG1587	Uroporphyrinogen-III synthase
FOC38_20690	COG2959	enzyme of heme biosynthesis
FOC38_20695	COG3071	HemY protein
FOC38_20720	COG1113	amino acid transport
FOC38_20735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC38_20740	COG2244	polysaccharide biosynthetic process
FOC38_20745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC38_20750	COG0456	acetyltransferase
FOC38_20755	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC38_20760	COG1088	dTDP-glucose 4,6-dehydratase activity
FOC38_20765	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC38_20770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC38_20775	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC38_20780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC38_20785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC38_20790	COG3118	belongs to the thioredoxin family
FOC38_20800	COG0248	Ppx GppA phosphatase
FOC38_20815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC38_20825	COG3121	Chaperone
FOC38_20840	COG3121	Chaperone
FOC38_20895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC38_20900	COG0583	DNA-binding transcription factor activity
FOC38_20910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC38_20920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC38_20925	COG3978	acetolactate synthase activity
FOC38_20945	COG3085	chromosome segregation
FOC38_20950	COG0583	DNA-binding transcription factor activity
FOC38_20955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_20960	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_20965	COG1129	ABC transporter
FOC38_20970	COG1879	ABC-type sugar transport system periplasmic component
FOC38_21015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC38_21025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC38_21040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC38_21050	COG0678	peroxiredoxin activity
FOC38_21050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC38_21055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC38_21100	COG1629	transport
FOC38_21105	COG0165	Argininosuccinate lyase
FOC38_21115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOC38_21125	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOC38_21135	COG0527	aspartate kinase activity
FOC38_21135	COG0460	homoserine dehydrogenase
FOC38_21140	COG0626	cystathionine gamma-synthase activity
FOC38_21145	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FOC38_21150	COG0254	rRNA binding
FOC38_21155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC38_21160	COG1609	Transcriptional regulator
FOC38_21165	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOC38_21170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOC38_21175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOC38_21180	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC38_21190	COG3074	FtsZ-dependent cytokinesis
FOC38_21195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC38_21200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC38_21205	COG1494	fructose-1,6-bisphosphatase
FOC38_21210	COG2814	Major facilitator Superfamily
FOC38_21230	COG3152	Membrane
FOC38_21245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOC38_21255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC38_21270	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FOC38_21285	COG3678	ATP-independent chaperone mediated protein folding
FOC38_21290	COG0745	RESPONSE REGULATOR receiver
FOC38_21295	COG2205	protein histidine kinase activity
FOC38_21300	COG2169	Transcriptional regulator
FOC38_21300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC38_21305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC38_21310	COG1045	serine acetyltransferase
FOC38_21315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC38_21320	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOC38_21325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC38_21330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC38_21335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC38_21340	COG4942	peptidase
FOC38_21345	COG2861	carbohydrate metabolic process
FOC38_21355	COG0156	8-amino-7-oxononanoate synthase activity
FOC38_21360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC38_21365	COG0859	PFAM glycosyl transferase family 9
FOC38_21370	COG0859	PFAM glycosyl transferase family 9
FOC38_21375	COG1519	Transferase
FOC38_21385	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC38_21395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC38_21400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC38_21405	COG2003	Belongs to the UPF0758 family
FOC38_21410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC38_21415	COG0756	dUTP diphosphatase activity
FOC38_21420	COG1309	transcriptional regulator
FOC38_21425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOC38_21430	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOC38_21435	COG1561	YicC-like family, N-terminal region
FOC38_21440	COG3645	SOS response
FOC38_21460	COG5001	Diguanylate cyclase
FOC38_21465	COG1024	Enoyl-CoA hydratase
FOC38_21470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC38_21480	COG2860	membrane
FOC38_21485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC38_21495	COG1758	RNA polymerase activity
FOC38_21500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC38_21505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC38_21510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC38_21515	COG0786	glutamate:sodium symporter activity
FOC38_21520	COG2233	PERMEase
FOC38_21525	COG2982	Protein involved in outer membrane biogenesis
FOC38_21545	COG3423	Transcriptional regulator
FOC38_21560	COG2204	response regulator
FOC38_21565	COG0456	acetyltransferase
FOC38_21570	COG1490	D-aminoacyl-tRNA deacylase activity
FOC38_21575	COG1295	ribonuclease BN
FOC38_21580	COG1011	Hydrolase
FOC38_21590	COG0174	glutamine synthetase
FOC38_21595	COG3852	Histidine kinase
FOC38_21605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC38_21615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOC38_21620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC38_21620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC38_21625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC38_21630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC38_21635	COG3084	Protein conserved in bacteria
FOC38_21645	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC38_21675	COG2186	Transcriptional regulator
FOC38_21680	COG0477	Major facilitator Superfamily
FOC38_21685	COG1609	Transcriptional regulator
FOC38_21690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC38_21695	COG1879	ABC-type sugar transport system periplasmic component
FOC38_21700	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC38_21710	COG1869	D-ribose catabolic process
FOC38_21715	COG3158	transport of potassium into the cell
FOC38_21720	COG0714	Associated with various cellular activities
FOC38_21725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOC38_21735	COG2502	aspartate--ammonia ligase
FOC38_21740	COG1522	sequence-specific DNA binding
FOC38_21745	COG0716	FMN binding
FOC38_21750	COG0445	tRNA wobble uridine modification
FOC38_21755	COG0357	Ribosomal RNA small subunit methyltransferase G
FOC38_21760	COG3312	ion transport
FOC38_21765	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC38_21775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOC38_21780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC38_21785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOC38_21795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOC38_21800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOC38_21805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC38_21810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC38_21855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC38_21860	COG0573	inorganic phosphate transmembrane transporter activity
FOC38_21865	COG0581	inorganic phosphate transmembrane transporter activity
FOC38_21875	COG0704	Plays a role in the regulation of phosphate uptake
FOC38_21885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC38_21890	COG0765	amino acid transport
FOC38_21895	COG0765	amino acid transport
FOC38_21900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC38_21905	COG2252	PERMEase
FOC38_21920	COG4191	Histidine kinase
FOC38_21925	COG0431	NADPH-dependent FMN reductase
FOC38_21930	COG0840	transmembrane signaling receptor activity
FOC38_21935	COG2011	ABC-type metal ion transport system permease component
FOC38_21940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC38_21950	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOC38_21955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC38_21960	COG0706	membrane insertase activity
FOC38_21970	COG0594	ribonuclease P activity
FOC38_21975	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC38_21985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC38_21990	COG0592	DNA-directed DNA polymerase activity
FOC38_22000	COG0187	DNA topoisomerase II activity
FOC38_22005	COG0561	phosphatase activity
FOC38_22010	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC38_22020	COG1940	carbohydrate kinase activity
FOC38_22025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC38_22035	COG2723	6-phospho-beta-galactosidase activity
FOC38_22040	COG2188	Transcriptional regulator
FOC38_22045	COG2423	ornithine cyclodeaminase activity
FOC38_22060	COG2186	Transcriptional regulator
FOC38_22065	COG3734	2-keto-3-deoxy-galactonokinase
FOC38_22070	COG0800	Aldolase
FOC38_22075	COG4948	Mandelate Racemase Muconate Lactonizing
FOC38_22080	COG2271	Major facilitator Superfamily
FOC38_22085	COG0823	Involved in the tonB-independent uptake of proteins
FOC38_22090	COG5645	(Lipo)protein
FOC38_22110	COG3977	Valine--pyruvate aminotransferase
FOC38_22115	COG0366	Alpha amylase catalytic
FOC38_22135	COG2885	chlorophyll binding
FOC38_22150	COG0456	acetyltransferase
FOC38_22155	COG2818	Glycosylase
FOC38_22165	COG0751	glycine-tRNA ligase activity
FOC38_22175	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_22175	COG2213	PTS system mannitol-specific
FOC38_22180	COG0246	Mannitol dehydrogenase
FOC38_22185	COG3722	fumarate hydratase activity
FOC38_22195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC38_22210	COG3077	Addiction module antitoxin, RelB DinJ family
FOC38_22215	COG2258	MOSC domain
FOC38_22220	COG0840	transmembrane signaling receptor activity
FOC38_22225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC38_22230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC38_22240	COG0437	4 iron, 4 sulfur cluster binding
FOC38_22245	COG2864	formate dehydrogenase
FOC38_22250	COG3058	Necessary for formate dehydrogenase activity
FOC38_22255	COG1921	L-seryl-tRNASec selenium transferase activity
FOC38_22260	COG3276	selenocysteine insertion sequence binding
FOC38_22270	COG3274	enterobacterial common antigen metabolic process
FOC38_22280	COG1335	isochorismatase
FOC38_22290	COG3188	usher protein
FOC38_22295	COG3121	Chaperone
FOC38_22305	COG1070	Carbohydrate kinase
FOC38_22310	COG2115	Belongs to the xylose isomerase family
FOC38_22315	COG4213	ABC transporter substrate-binding protein
FOC38_22325	COG4214	carbohydrate transport
FOC38_22330	COG1609	Transcriptional regulator
FOC38_22330	COG2207	Transcriptional regulator
FOC38_22345	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOC38_22350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC38_22370	COG3623	hexulose-6-phosphate isomerase
FOC38_22395	COG3121	Chaperone
FOC38_22400	COG3539	Fimbrial protein
FOC38_22410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOC38_22415	COG2986	histidine ammonia-lyase
FOC38_22435	COG1764	response to oxidative stress
FOC38_22440	COG2194	sulfuric ester hydrolase activity
FOC38_22445	COG2197	response regulator
FOC38_22450	COG3851	Histidine kinase
FOC38_22455	COG2271	Major facilitator Superfamily
FOC38_22465	COG0747	negative chemotaxis
FOC38_22470	COG0601	transmembrane transport
FOC38_22475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC38_22480	COG0444	Belongs to the ABC transporter superfamily
FOC38_22485	COG4608	Belongs to the ABC transporter superfamily
FOC38_22490	COG2194	sulfuric ester hydrolase activity
FOC38_22510	COG1192	Involved in chromosome partitioning
FOC38_22520	COG1215	transferase activity, transferring glycosyl groups
FOC38_22525	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC38_22530	COG3118	belongs to the thioredoxin family
FOC38_22530	COG0457	Tetratricopeptide repeat
FOC38_22535	COG2200	EAL domain
FOC38_22535	COG2199	diguanylate cyclase activity
FOC38_22545	COG3121	Chaperone
FOC38_22550	COG3188	usher protein
FOC38_22560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC38_22575	COG1301	dicarboxylic acid transport
FOC38_22580	COG0612	Peptidase, M16
FOC38_22585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC38_22590	COG1942	4-Oxalocrotonate Tautomerase
FOC38_22595	COG2200	EAL domain
FOC38_22600	COG2982	Protein involved in outer membrane biogenesis
FOC38_22605	COG2134	cdp-diacylglycerol pyrophosphatase
FOC38_22610	COG1295	ribonuclease BN
FOC38_22625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC38_22630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOC38_22640	COG0742	ribosomal rna small subunit methyltransferase
FOC38_22645	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity