locus-tag	class	description
HRD70_00005	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HRD70_00010	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HRD70_00015	ENOG4108T8E	UPF0325 protein
HRD70_00020	ENOG4105QDK	Flavodoxin
HRD70_00025	ENOG4105DR9	pseudouridine synthase
HRD70_00030	ENOG4105WP7	tRNA pseudouridine synthase C
HRD70_00040	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HRD70_00045	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HRD70_00050	ENOG4105EWT	decarboxylase family
HRD70_00055	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HRD70_00060	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HRD70_00065	ENOG4105M08	Membrane
HRD70_00070	ENOG4105ETT	transcriptional Regulator, LysR family
HRD70_00080	ENOG4105M5B	(LipO)protein
HRD70_00085	ENOG4105C9B	Cysteine desulfurase
HRD70_00090	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HRD70_00095	ENOG4105CUZ	uba thif-type nad fad binding protein
HRD70_00100	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HRD70_00120	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HRD70_00125	ENOG4107QZM	n-acetylglutamate synthase
HRD70_00130	ENOG4107QYX	exodeoxyribonuclease v alpha
HRD70_00140	ENOG4107QXK	peptidase
HRD70_00145	ENOG4105DSY	exodeoxyribonuclease V, gamma
HRD70_00150	ENOG4105RVB	Prepilin peptidase dependent protein c
HRD70_00175	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HRD70_00180	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HRD70_00185	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HRD70_00190	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
HRD70_00195	ENOG4105EE5	Membrane protein terC
HRD70_00200	ENOG4105CPC	Aldo Keto reductase
HRD70_00205	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HRD70_00210	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD70_00220	ENOG41060NJ	transcriptional regulator
HRD70_00230	ENOG4105RQF	LysR family Transcriptional regulator
HRD70_00235	ENOG4105F27	Major Facilitator
HRD70_00240	ENOG4105EJC	lysr family transcriptional regulator
HRD70_00255	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_00305	ENOG4108VAU	general secretion pathway protein G
HRD70_00310	ENOG4105D7Q	type ii secretion system
HRD70_00315	ENOG4107QHF	type ii secretion system protein e
HRD70_00335	ENOG4107B2H	carbonic anhydrase
HRD70_00340	ENOG4105KVH	Transcriptional regulator
HRD70_00345	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HRD70_00355	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
HRD70_00360	ENOG4105DVC	DnaJ domain protein
HRD70_00365	ENOG4105CQ4	Transcriptional regulator
HRD70_00370	ENOG4105DPW	Major facilitator superfamily MFS_1
HRD70_00385	ENOG4105F7P	transcriptional regulator AsnC family
HRD70_00390	ENOG4105BZU	Histidine kinase
HRD70_00405	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
HRD70_00440	ENOG4105CNN	ABC, transporter
HRD70_00450	ENOG4105DKQ	ROK family
HRD70_00470	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD70_00480	ENOG4105CRK	lysyL-tRNA synthetase
HRD70_00490	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HRD70_00495	ENOG4105T95	Thiol disulfide interChange protein
HRD70_00500	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD70_00505	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HRD70_00510	ENOG4105CT7	inner membrane cred family protein
HRD70_00515	ENOG4105EB3	Histidine kinase
HRD70_00520	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD70_00535	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HRD70_00540	ENOG4108UT2	hemolysin iii
HRD70_00550	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HRD70_00560	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HRD70_00565	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HRD70_00570	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HRD70_00575	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HRD70_00580	ENOG4105D0A	hydroxylase
HRD70_00585	ENOG4107RAQ	aminopeptidase
HRD70_00590	ENOG4105E07	UPF0149 protein
HRD70_00595	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HRD70_00605	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HRD70_00610	ENOG4108JQ1	Dehydrogenase
HRD70_00615	ENOG4105E66	phosphoriboisomerase A
HRD70_00620	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HRD70_00625	ENOG4105MPN	Membrane
HRD70_00630	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HRD70_00635	ENOG4105D64	Mechanosensitive ion channel
HRD70_00640	ENOG4105D2N	Aldolase
HRD70_00645	ENOG4105BZA	Phosphoglycerate kinase
HRD70_00650	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HRD70_00655	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HRD70_00660	ENOG4108K0D	peptidase, M48
HRD70_00670	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HRD70_00675	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HRD70_00690	ENOG41080HT	Transcriptional regulator, arsr family
HRD70_00695	ENOG4105GPY	SprT protein
HRD70_00700	ENOG4105RWS	endonuclease I
HRD70_00705	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HRD70_00710	ENOG4105D7Z	glutathione synthase
HRD70_00715	ENOG4108UJU	UPF0301 protein
HRD70_00720	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HRD70_00725	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HRD70_00735	ENOG4105CZX	twitching motility protein
HRD70_00740	ENOG4105DFA	alanine racemase domain protein
HRD70_00745	ENOG4105II7	pyrroline-5-carboxylate reductase
HRD70_00750	ENOG4108VIA	integral membrane protein
HRD70_00755	ENOG4105VZ9	UPF0235 protein
HRD70_00760	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRD70_00765	ENOG4105CSA	Coproporphyrinogen iii oxidase
HRD70_00770	ENOG4105K33	Periplasmic Protein
HRD70_00780	ENOG41090ED	Protein with unknown function (DUF469)
HRD70_00785	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HRD70_00790	ENOG4105CEN	a g-specific adenine glycosylase
HRD70_00795	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HRD70_00800	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HRD70_00810	ENOG4105CXN	decarboxylase
HRD70_00820	ENOG4105C6N	Formate acetyltransferase
HRD70_00825	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HRD70_00830	ENOG4108MST	Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity)
HRD70_00835	ENOG4105C7B	Threonine dehydratase
HRD70_00855	ENOG4105HY2	Glycosidase related protein
HRD70_00860	ENOG4105CG3	alpha amylase, catalytic region
HRD70_00865	ENOG4105DRS	transport system, permease
HRD70_00880	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_00890	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_00900	ENOG4105DFD	Na H antiporter
HRD70_00975	ENOG4105NVB	glycoside hydrolase, family 19
HRD70_00985	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD70_00995	ENOG4108ZG0	Ompa motb domain protein
HRD70_01020	ENOG4105E7U	AraC family transcriptional regulator
HRD70_01025	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HRD70_01040	ENOG4108MI0	Resistance protein
HRD70_01045	ENOG4105J12	Multidrug resistance protein mdtN
HRD70_01065	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HRD70_01070	ENOG4108IPW	abc transporter atp-binding protein
HRD70_01075	ENOG4105CM4	permease protein
HRD70_01105	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_01115	ENOG4105EAM	Na Pi-cotransporter
HRD70_01120	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HRD70_01125	ENOG4105CFC	Transporter
HRD70_01145	ENOG4107RA9	decarboxylase
HRD70_01155	ENOG4105CSH	Transporter
HRD70_01165	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HRD70_01180	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HRD70_01185	ENOG4105C8H	hydrogenase maturation protein Hypf
HRD70_01190	ENOG4105C45	hydrogenase expression formation protein (HypE)
HRD70_01195	ENOG4105CQS	hydrogenase expression formation protein HypD
HRD70_01200	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
HRD70_01205	ENOG4107RSS	Hydrogenase accessory protein HypB
HRD70_01210	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HRD70_01215	ENOG4108WGS	hydrogenase 2-specific chaperone
HRD70_01220	ENOG4108USZ	hydrogenase
HRD70_01225	ENOG4105DPX	Hydrogenase, large subunit
HRD70_01230	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
HRD70_01235	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD70_01240	ENOG4105E3S	small subunit
HRD70_01245	ENOG4108XTF	Outer Membrane Lipoprotein
HRD70_01265	ENOG4105EXW	epimerase dehydratase
HRD70_01270	ENOG4105CSP	Major Facilitator Superfamily
HRD70_01275	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HRD70_01280	ENOG4105WQI	isochorismatase
HRD70_01285	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HRD70_01290	ENOG4105E4F	Isochorismate synthase
HRD70_01295	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
HRD70_01305	ENOG4105E0A	ABC, transporter
HRD70_01310	ENOG4105TVJ	transport system, permease
HRD70_01315	ENOG4105DQ5	transport system permease protein
HRD70_01325	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD70_01340	ENOG4105E0K	tonB-dependent siderophore receptor
HRD70_01360	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HRD70_01365	ENOG4108IJF	Heavy metal efflux pump, CzcA
HRD70_01370	ENOG4105CF1	Alkylated DNA repair protein
HRD70_01445	ENOG4108ZZF	transport protein (ExbD)
HRD70_01450	ENOG4105CWK	Biopolymer transport protein, ExbB
HRD70_01455	ENOG4105C28	cystathionine
HRD70_01460	ENOG4108K81	inner membrane protein YghB
HRD70_01465	ENOG4105CF7	AraC family transcriptional regulator
HRD70_01470	ENOG4108I6A	alcohol dehydrogenase
HRD70_01475	ENOG4105CV8	reductase
HRD70_01485	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HRD70_01490	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HRD70_01495	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD70_01500	ENOG4108UZY	PTS System
HRD70_01505	ENOG4105ETZ	PTS System
HRD70_01510	ENOG4105F3R	pts system mannose fructose sorbose family iid
HRD70_01525	ENOG4105E0F	Histidine kinase
HRD70_01535	ENOG4105NF4	modulator of drug activity
HRD70_01540	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HRD70_01545	ENOG4105JQN	Transcriptional regulator
HRD70_01550	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD70_01555	ENOG4105IPS	esterase
HRD70_01560	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HRD70_01565	ENOG4108SX3	cytoplasmic protein
HRD70_01570	ENOG41087AY	ADP-Ribose pyrophosphatase
HRD70_01575	ENOG4105DFG	type I secretion outer membrane protein
HRD70_01580	ENOG4105F1G	UPF0441 protein
HRD70_01585	ENOG4106032	Glutathionylspermidine synthase
HRD70_01590	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HRD70_01595	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HRD70_01600	ENOG4105W0Z	cytoplasmic protein
HRD70_01605	ENOG4105DVH	amino acid
HRD70_01610	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HRD70_01615	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HRD70_01620	ENOG4105I7R	Adenylate cyclase
HRD70_01625	ENOG4106MWK	domain protein
HRD70_01630	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HRD70_01635	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HRD70_01640	ENOG4107ZVW	dihydroneopterin aldolase
HRD70_01645	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HRD70_01650	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRD70_01660	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HRD70_01665	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD70_01685	ENOG4105EHZ	conserved protein UCP016719
HRD70_01695	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HRD70_01700	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
HRD70_01705	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HRD70_01710	ENOG4105C5Y	PTS System
HRD70_01720	ENOG4105E5D	amino acid
HRD70_01725	ENOG4105CVK	Glutamate decarboxylase
HRD70_01740	ENOG4108YK4	Acid-resistance membrane protein
HRD70_01745	ENOG4108594	Permease of the drug metabolite transporter
HRD70_01755	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HRD70_01760	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HRD70_01770	ENOG4108VKG	metal-dependent hydrolase
HRD70_01775	ENOG4105EE0	oxidoreductase
HRD70_01780	ENOG4105DU1	integral membrane protein, terc
HRD70_01785	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HRD70_01790	ENOG4105P66	Membrane
HRD70_01795	ENOG4105CTX	dehydratase
HRD70_01800	ENOG4107QZW	Altronate oxidoreductase
HRD70_01805	ENOG4105D2H	Uronic isomerase
HRD70_01810	ENOG4105DPW	Major facilitator superfamily MFS_1
HRD70_01825	ENOG4106W5V	Membrane
HRD70_01840	ENOG4105NE1	Conserved Protein
HRD70_01845	ENOG41090KG	Inner membrane protein YqjE
HRD70_01850	ENOG4105YJD	
HRD70_01855	ENOG4108VBZ	doxx family
HRD70_01860	ENOG4105CHF	Glutathione S-transferase
HRD70_01865	ENOG4105CWB	LysR family transcriptional Regulator
HRD70_01870	ENOG4108CNN	domain protein
HRD70_01875	ENOG4105DQ4	alcohol dehydrogenase
HRD70_01880	ENOG4105EMU	Dehydrogenase
HRD70_01890	ENOG4107SET	aldo keto reductase
HRD70_01895	ENOG4105EQ2	LysR family Transcriptional regulator
HRD70_01930	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HRD70_01940	ENOG41082RQ	UPF0102 protein
HRD70_01945	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HRD70_01950	ENOG4105W4M	Transport-associated protein
HRD70_01955	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HRD70_01960	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HRD70_01965	ENOG4105BZU	Histidine kinase
HRD70_01970	ENOG4105N5T	Radical SAM Protein
HRD70_01975	ENOG4105CBC	glutamate synthase
HRD70_01980	ENOG4105BZ8	glutamate synthase
HRD70_01990	ENOG4105KB2	stringent starvation protein b
HRD70_01995	ENOG4107MKT	Stringent starvation protein a
HRD70_02000	ENOG4108UJD	30S ribosomal protein S9
HRD70_02005	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HRD70_02010	ENOG4105D6Z	AFG1 family ATPase
HRD70_02015	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HRD70_02020	ENOG4105C0H	protease
HRD70_02025	ENOG4105C0H	protease
HRD70_02030	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HRD70_02035	ENOG4105VFK	BolA family
HRD70_02040	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
HRD70_02045	ENOG4105E3I	toluene tolerance
HRD70_02050	ENOG4107PE3	Mammalian cell entry related domain protein
HRD70_02055	ENOG4105CY3	ABC transporter, permease
HRD70_02060	ENOG4105DHJ	ABC, transporter
HRD70_02065	ENOG4105FEU	K -dependent Na -Ca exchanger
HRD70_02070	ENOG4105C2X	Arabinose 5-phosphate isomerase
HRD70_02075	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HRD70_02080	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HRD70_02085	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HRD70_02090	ENOG4108IUZ	ABC transporter
HRD70_02095	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD70_02100	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HRD70_02105	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HRD70_02110	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HRD70_02115	ENOG41080Z8	PHOSPHOCARRIER protein
HRD70_02120	ENOG4105CXT	aspartate transcarbamylase
HRD70_02125	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HRD70_02130	ENOG4105KME	endoribonuclease L-psp
HRD70_02135	ENOG4105CG3	alpha amylase, catalytic region
HRD70_02140	ENOG4105C5Y	PTS System
HRD70_02145	ENOG4105D4X	repressor
HRD70_02155	ENOG4105EMD	TRANSCRIPTIONal
HRD70_02160	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HRD70_02175	ENOG41069H0	dihydroorotase EC 3.5.2.3
HRD70_02205	ENOG4105NXH	GreA GreB family elongation factor
HRD70_02210	ENOG4108XVM	Cytochrome b(562)
HRD70_02215	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HRD70_02220	ENOG4105N42	UPF0307 protein
HRD70_02225	ENOG4105UNR	(Barnase) inhibitor
HRD70_02235	ENOG4105C26	Dehydrogenase
HRD70_02240	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
HRD70_02245	ENOG4105Y49	secretion protein, HlyD family
HRD70_02255	ENOG4105CR8	Transcriptional regulator
HRD70_02260	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HRD70_02270	ENOG4105QD6	exported protein
HRD70_02275	ENOG4105C03	ribonuclease
HRD70_02280	ENOG4108Z03	MAF-like protein
HRD70_02285	ENOG4105VQ7	Rod shape-determining protein MreD
HRD70_02290	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HRD70_02300	ENOG41062P1	Diguanylate cyclase phosphodiesterase
HRD70_02305	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HRD70_02315	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HRD70_02320	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HRD70_02325	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HRD70_02330	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HRD70_02335	ENOG4105RG0	Membrane
HRD70_02340	ENOG4108IA2	Sodium pantothenate symporter
HRD70_02345	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HRD70_02350	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HRD70_02355	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HRD70_02365	ENOG4105BZU	Histidine kinase
HRD70_02370	ENOG4108XTF	Outer Membrane Lipoprotein
HRD70_02375	ENOG4105VEQ	Cold shock protein
HRD70_02380	ENOG4105VEQ	Cold shock protein
HRD70_02385	ENOG4105VEQ	Cold shock protein
HRD70_02390	ENOG4107QPK	)-transporter
HRD70_02395	ENOG4105D1S	lipid A biosynthesis
HRD70_02415	ENOG4105CMU	LysR family (Transcriptional regulator
HRD70_02420	ENOG4105EEQ	Na H antiporter
HRD70_02425	ENOG4105C7N	Xanthine uracil vitamin C permease
HRD70_02435	ENOG4108UUM	single-stranded DNA-binding protein
HRD70_02440	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HRD70_02445	ENOG4105MSB	protein, conserved in bacteria
HRD70_02450	ENOG4105CGF	Aromatic amino acid aminotransferase
HRD70_02460	ENOG4105CDU	Replicative dna helicase
HRD70_02465	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HRD70_02470	ENOG4105P4Z	Phage shock protein G
HRD70_02475	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HRD70_02480	ENOG4105MYN	Zinc uptake regulation protein
HRD70_02485	ENOG4105VDW	Csbd family
HRD70_02490	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HRD70_02495	ENOG41080IJ	Diacylglycerol kinase
HRD70_02500	ENOG4105E55	glycerol-3-phosphate acyltransferase
HRD70_02505	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HRD70_02510	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HRD70_02520	ENOG4107W52	maltose operon periplasmic protein
HRD70_02525	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HRD70_02535	ENOG4107FKK	extracellular solute-binding protein family 1
HRD70_02540	ENOG4105D56	permease protein
HRD70_02545	ENOG4105EG2	ABC transporter, permease
HRD70_02550	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HRD70_02560	ENOG4105CFH	Aspartokinase
HRD70_02565	ENOG4105C09	Bile acid
HRD70_02580	ENOG4105C3R	Methionine synthase
HRD70_02585	ENOG41069M3	Transcriptional regulator
HRD70_02590	ENOG4105BZU	Histidine kinase
HRD70_02595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRD70_02600	ENOG4107QP7	CoA-transferase subunit A
HRD70_02605	ENOG4107QNJ	CoA-transferase subunit B
HRD70_02610	ENOG4105CRW	Short chain fatty acid transporter
HRD70_02615	ENOG4105CHU	acetyl-coa acetyltransferase
HRD70_02620	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HRD70_02625	ENOG4108I9X	Isocitrate lyase
HRD70_02630	ENOG4107QP3	malate synthase g
HRD70_02635	ENOG4105CVG	Homoserine O-transsuccinylase
HRD70_02680	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HRD70_02685	ENOG4105C12	Phosphoribosylglycinamide synthetase
HRD70_02690	ENOG4108T8B	Protein of unknown function (DUF1481)
HRD70_02700	ENOG4105R2J	Conserved Protein
HRD70_02705	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HRD70_02710	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HRD70_02715	ENOG4105E09	nadh pyrophosphatase
HRD70_02720	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
HRD70_02735	ENOG4105D06	uba thif-type nad fad binding protein
HRD70_02740	ENOG4105WHD	thiamine biosynthesis protein ThiS
HRD70_02745	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HRD70_02750	ENOG4105D41	biosynthesis protein thiH
HRD70_02760	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRD70_02770	ENOG4108VZM	50s ribosomal protein L10
HRD70_02775	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HRD70_02780	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HRD70_02785	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HRD70_02790	ENOG4105PM1	preprotein translocase subunit SecE
HRD70_02795	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRD70_02830	ENOG4105CS9	pantothenic acid kinase
HRD70_02835	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HRD70_02870	ENOG4108Z0R	Transferase
HRD70_02875	ENOG4105E2X	shikimate dehydrogenase
HRD70_02880	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRD70_02885	ENOG4108WI1	Dna topoisomerase
HRD70_02895	ENOG4105C79	DNA protecting protein DprA
HRD70_02900	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HRD70_02905	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HRD70_02910	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HRD70_02915	ENOG4105C1A	potassium transporter peripheral membrane
HRD70_02920	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HRD70_02925	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HRD70_02930	ENOG4105W1Y	Transcriptional regulator
HRD70_02935	ENOG4105VTS	DnaJ-like, subfamily C
HRD70_02940	ENOG4108ZT0	50S ribosomal protein l17
HRD70_02945	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRD70_02950	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HRD70_02955	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HRD70_02960	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HRD70_02970	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HRD70_02975	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HRD70_02980	ENOG4105VPB	50S ribosomal protein L30
HRD70_02985	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HRD70_02990	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HRD70_02995	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HRD70_03005	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HRD70_03015	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HRD70_03025	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HRD70_03030	ENOG41083MP	50s ribosomal protein l29
HRD70_03035	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HRD70_03040	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HRD70_03045	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HRD70_03050	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HRD70_03060	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HRD70_03070	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HRD70_03090	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRD70_03100	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HRD70_03110	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HRD70_03115	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HRD70_03120	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HRD70_03125	ENOG4105WWK	YheO domain protein
HRD70_03140	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HRD70_03145	ENOG4105VKU	nucleicacid-binding protein
HRD70_03155	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HRD70_03160	ENOG4105C5H	ABC transporter
HRD70_03170	ENOG4105E2B	Taurine dioxygenase
HRD70_03175	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HRD70_03185	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HRD70_03190	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HRD70_03200	ENOG4105DNZ	Alpha Beta Hydrolase
HRD70_03205	ENOG4105YP7	UPF0270 protein
HRD70_03210	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HRD70_03215	ENOG4108UKZ	OsmC family
HRD70_03220	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HRD70_03225	ENOG410613R	integral membrane protein, YccS YhfK family
HRD70_03230	ENOG4105C8Y	Acetylornithine aminotransferase
HRD70_03245	ENOG4105D7A	ATP-binding protein
HRD70_03250	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HRD70_03255	ENOG4105F8D	glycoside hydrolase family 4
HRD70_03260	ENOG41060NJ	transcriptional regulator
HRD70_03265	ENOG4106DTQ	Protein TsgA homolog
HRD70_03270	ENOG4105DZC	cytosine deaminase
HRD70_03275	ENOG4107QZF	nitrite reductase NADPH large subunit
HRD70_03280	ENOG4105WZK	nitrite reductase NADPH small subunit
HRD70_03285	ENOG4107V9H	nitrite transporter
HRD70_03290	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRD70_03295	ENOG4105C31	Tryptophanyl-tRNA synthetase
HRD70_03305	ENOG4105DJV	ribulose-phosphate 3-epimerase
HRD70_03325	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HRD70_03355	ENOG4108JQC	penicillin-binding protein 1A
HRD70_03360	ENOG4107RK2	ADP-ribose diphosphatase NudE
HRD70_03365	ENOG4105DQY	intracellular growth attenuator
HRD70_03370	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HRD70_03375	ENOG4105VEJ	Heat shock protein
HRD70_03385	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HRD70_03390	ENOG4105E0F	Histidine kinase
HRD70_03400	ENOG4108RRZ	Transcription elongation factor GreB
HRD70_03405	ENOG4105BZM	domain protein
HRD70_03410	ENOG4105XFK	Ferrous iron transport protein A
HRD70_03415	ENOG4105CE1	Ferrous iron transport protein b
HRD70_03420	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
HRD70_03425	ENOG4105RID	UPF0379 protein yhcN
HRD70_03430	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HRD70_03435	ENOG4105MJ2	Competence protein
HRD70_03440	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HRD70_03445	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HRD70_03450	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HRD70_03455	ENOG41061ZR	Transcriptional regulator
HRD70_03465	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HRD70_03470	ENOG4105E98	transcriptional regulator DeoR family
HRD70_03475	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HRD70_03480	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HRD70_03485	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HRD70_03495	ENOG4108IUM	Glycogen debranching enzyme
HRD70_03500	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HRD70_03505	ENOG4108HRK	Histidine kinase
HRD70_03510	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HRD70_03515	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HRD70_03520	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HRD70_03525	ENOG4105C6Z	Gluconate
HRD70_03530	ENOG4105DIQ	Transcriptional regulator
HRD70_03535	ENOG4105C2I	pirin domain protein
HRD70_03540	ENOG4105WCN	acetyltransferase
HRD70_03545	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
HRD70_03550	ENOG4105F0H	myo-inositol catabolism protein
HRD70_03555	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HRD70_03560	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HRD70_03575	ENOG4105DH8	myo-inositol catabolism
HRD70_03580	ENOG4105C26	Dehydrogenase
HRD70_03590	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HRD70_03600	ENOG4108HCJ	Hydrolase
HRD70_03605	ENOG4105CBX	hi0933 family
HRD70_03610	ENOG4105CJ3	phosphate transporter
HRD70_03615	ENOG4108V6B	universal stress protein B
HRD70_03620	ENOG4108M6U	Universal stress protein A
HRD70_03635	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HRD70_03640	ENOG4105DGW	oligopeptidase A
HRD70_03645	ENOG4105D6S	protein involved in catabolism of external DNA
HRD70_03650	ENOG4105DC8	reductase
HRD70_03660	ENOG4108IMY	Transcriptional regulator
HRD70_03665	ENOG4107H3J	ribonuclease
HRD70_03670	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
HRD70_03675	ENOG41066T0	asmA family
HRD70_03680	ENOG4105CMB	EAL domain-containing protein
HRD70_03685	ENOG4105VSH	4-oxalocrotonate tautomerase
HRD70_03690	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HRD70_03695	ENOG4105CS0	peptidase
HRD70_03700	ENOG4105CK2	sodium dicarboxylate symporter
HRD70_03710	ENOG4108PU9	oligogalacturonate-specific porin
HRD70_03715	ENOG4105BZU	Histidine kinase
HRD70_03720	ENOG4105EJG	cellulose synthase
HRD70_03725	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HRD70_03730	ENOG4107EEX	Cellulose synthase regulator protein
HRD70_03735	ENOG4107QZ7	Cellulose synthase catalytic subunit
HRD70_03740	ENOG4105UTS	cellulose synthase operon protein YhjQ
HRD70_03750	ENOG4105U74	cellulose biosynthesis protein BcsE
HRD70_03755	ENOG4105WQA	Cellulose biosynthesis protein BcsF
HRD70_03760	ENOG4105D1V	cellulose synthase operon protein YhjU
HRD70_03765	ENOG4108JQ7	(ABC) transporter
HRD70_03770	ENOG4105C3U	ABC transporter
HRD70_03775	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD70_03780	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD70_03785	ENOG4105DEF	Extracellular solute-binding protein, family 5
HRD70_03790	ENOG4105CKT	filamentous hemagglutinin
HRD70_03795	ENOG4105D5K	Hemolysin activator protein
HRD70_03800	ENOG4105CKT	filamentous hemagglutinin
HRD70_03810	ENOG4105CXY	transporter
HRD70_03815	ENOG4105BZU	Histidine kinase
HRD70_03820	ENOG4108KX4	response regulator
HRD70_03825	ENOG4105DIJ	Phosphoethanolamine transferase
HRD70_03830	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HRD70_03845	ENOG4105C85	amino acid
HRD70_03850	ENOG4105C84	Histidine ammonia-lyase
HRD70_03855	ENOG4105CGP	Urocanate hydratase
HRD70_03860	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_03900	ENOG4105BZU	Histidine kinase
HRD70_03945	ENOG4105ZTC	transcriptional activator, Ogr delta
HRD70_03955	ENOG4105DFP	Integrase
HRD70_03965	ENOG4105T16	Transcriptional regulator (AraC family)
HRD70_03970	ENOG4108HWW	ABC transporter
HRD70_03980	ENOG4105DFW	ABC transporter
HRD70_03985	ENOG4105C93	Xylose Isomerase
HRD70_03990	ENOG4105CMG	Carbohydrate kinase
HRD70_03995	ENOG4108TTM	chaperone
HRD70_04000	ENOG4108RWI	nicotinamidase
HRD70_04010	ENOG4105MEV	Acyl-transferase
HRD70_04020	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HRD70_04025	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HRD70_04030	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HRD70_04035	ENOG4108MG3	formate dehydrogenase
HRD70_04040	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD70_04050	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HRD70_04055	ENOG41080ET	plasmid maintenance system killer protein
HRD70_04060	ENOG41081XE	plasmid maintenance system antidote protein, xre family
HRD70_04065	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HRD70_04070	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_04075	ENOG4108YYI	Protein of unknown function (DUF2810)
HRD70_04080	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HRD70_04090	ENOG4105E61	Mannitol repressor protein
HRD70_04095	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HRD70_04100	ENOG4105CTS	PTS system mannitol-specific
HRD70_04110	ENOG4106JH6	(LipO)protein
HRD70_04115	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HRD70_04120	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HRD70_04125	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HRD70_04130	ENOG4105HNP	-acetyltransferase
HRD70_04160	ENOG4105C5I	Dehydrogenase
HRD70_04175	ENOG4107T9C	Alpha amylase catalytic region
HRD70_04180	ENOG4105JKW	Valine--pyruvate aminotransferase
HRD70_04185	ENOG4105D0C	transport protein
HRD70_04200	ENOG4105R2A	(LipO)protein
HRD70_04205	ENOG4105D99	atp gtp-binding protein
HRD70_04210	ENOG4108SGR	YheO domain-containing protein
HRD70_04225	ENOG4105FDP	GntR family transcriptional regulator
HRD70_04230	ENOG4105CS2	ec 3.2.1.21
HRD70_04240	ENOG4105CK1	PTS System
HRD70_04245	ENOG41066F8	ROK family
HRD70_04255	ENOG4105VCP	PTS System
HRD70_04260	ENOG410667J	hydrolase
HRD70_04265	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD70_04270	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HRD70_04275	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HRD70_04280	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HRD70_04290	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HRD70_04300	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HRD70_04305	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HRD70_04310	ENOG4105RKW	reductase (By
HRD70_04320	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_04325	ENOG4108UMI	ABC transporter, permease
HRD70_04330	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_04335	ENOG4108YYH	Nadph-dependent fmn reductase
HRD70_04340	ENOG4105BZU	Histidine kinase
HRD70_04345	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HRD70_04355	ENOG4105C7N	Xanthine uracil vitamin C permease
HRD70_04360	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HRD70_04365	ENOG4105DRP	amino acid AbC transporter
HRD70_04370	ENOG4105EAD	ABC transporter
HRD70_04375	ENOG4106PMH	Extracellular solute-binding protein family 3
HRD70_04395	ENOG4105E2Z	phosphate ABC transporter (Permease
HRD70_04400	ENOG4105C8U	phosphate abc transporter
HRD70_04405	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HRD70_04415	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HRD70_04420	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HRD70_04425	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HRD70_04435	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HRD70_04440	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD70_04445	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD70_04450	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD70_04455	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HRD70_04460	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
HRD70_04465	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HRD70_04470	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HRD70_04475	ENOG4105QTB	Flavodoxin
HRD70_04480	ENOG4108VVK	transcriptional Regulator, AsnC
HRD70_04485	ENOG4105CU9	asparagine synthetase A
HRD70_04495	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HRD70_04500	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
HRD70_04510	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HRD70_04520	ENOG4105CNN	ABC, transporter
HRD70_04525	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HRD70_04530	ENOG4108RVA	ribokinase
HRD70_04535	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_04540	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD70_04545	ENOG4107EJG	GntR family transcriptional regulator
HRD70_04570	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HRD70_04580	ENOG4105PC1	Conserved Protein
HRD70_04585	ENOG4105E27	serine threonine protein kinase
HRD70_04590	ENOG4108Z33	Thiol disulfide Interchange Protein
HRD70_04595	ENOG4105C2M	dna polymerase I
HRD70_04600	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HRD70_04605	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HRD70_04610	ENOG4105D4P	Coproporphyrinogen iii oxidase
HRD70_04615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRD70_04620	ENOG4105CUX	Signal transduction histidine kinase
HRD70_04625	ENOG4105C5F	glutamine synthetase
HRD70_04630	ENOG4105CI3	gtp-binding protein typa
HRD70_04635	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
HRD70_04640	ENOG4107S2Z	UPF0761 membrane protein
HRD70_04645	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HRD70_04650	ENOG4105SUU	thioesterase domain
HRD70_04655	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD70_04665	ENOG4105JV1	AsmA family
HRD70_04670	ENOG4105C2W	permease
HRD70_04675	ENOG4105D6U	Sodium Glutamate Symporter
HRD70_04680	ENOG4105CB5	ATP-dependent DNA helicase recG
HRD70_04685	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HRD70_04690	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRD70_04695	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HRD70_04705	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
HRD70_04710	ENOG4105EN6	Membrane
HRD70_04720	ENOG4105D9N	nucleoside
HRD70_04725	ENOG4105E39	Enoyl-CoA hydratase
HRD70_04730	ENOG4105BZU	Histidine kinase
HRD70_04745	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HRD70_04765	ENOG4105ZUU	Transcriptional regulator
HRD70_04805	ENOG4105DSJ	YicC domain protein
HRD70_04820	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HRD70_04825	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HRD70_04830	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HRD70_04835	ENOG4105W5Q	DNA repair protein (RadC
HRD70_04840	ENOG4105KDC	50s ribosomal protein l28
HRD70_04845	ENOG4105W0E	50S ribosomal protein L33
HRD70_04850	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HRD70_04865	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HRD70_04870	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HRD70_04875	ENOG4105XA0	heptosyltransferase ii
HRD70_04880	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HRD70_04885	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HRD70_04890	ENOG4105CPQ	Dehydrogenase
HRD70_04895	ENOG4105PXI	polysaccharide deacetylase
HRD70_04900	ENOG41063SB	peptidase
HRD70_04905	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HRD70_04910	ENOG4107YZP	Rhodanese domain protein
HRD70_04915	ENOG4105VW4	glutaredoxin 3
HRD70_04925	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HRD70_04930	ENOG4105D7W	serine acetyltransferase
HRD70_04935	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HRD70_04940	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HRD70_04945	ENOG4105E0F	Histidine kinase
HRD70_04950	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD70_04955	ENOG4105FMW	periplasmic
HRD70_04960	ENOG41076HS	cation diffusion facilitator family transporter
HRD70_04970	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HRD70_04985	ENOG4105EBK	exported protein
HRD70_04990	ENOG4108VTS	Membrane
HRD70_04995	ENOG4105DP0	ferredoxin-NADP reductase
HRD70_05000	ENOG4105E5M	Multidrug resistance protein D
HRD70_05005	ENOG4105CBT	Fructose-1,6-bisphosphatase
HRD70_05010	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HRD70_05015	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HRD70_05020	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HRD70_05025	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HRD70_05030	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HRD70_05035	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HRD70_05040	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HRD70_05045	ENOG41063M6	Cell Division Protein
HRD70_05050	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_05055	ENOG4105C25	Primosomal protein n'
HRD70_05060	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HRD70_05065	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HRD70_05070	ENOG4105C28	cystathionine
HRD70_05075	ENOG4105CFH	Aspartokinase
HRD70_05080	ENOG4105SYT	Methylenetetrahydrofolate reductase
HRD70_05085	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HRD70_05095	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HRD70_05100	ENOG4105CAS	nag kinase
HRD70_05105	ENOG4105CH7	arginosuccinase
HRD70_05110	ENOG4105X58	receptor
HRD70_05135	ENOG4107QZV	Type I secretion membrane fusion protein
HRD70_05145	ENOG4107QN2	dihydrolipoyl dehydrogenase
HRD70_05150	ENOG4105EHV	domain protein
HRD70_05155	ENOG4105C5Q	Transcriptional regulator
HRD70_05160	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HRD70_05165	ENOG4105EJ2	Transcriptional regulator
HRD70_05170	ENOG4108Y73	Membrane
HRD70_05175	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HRD70_05185	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HRD70_05225	ENOG4105CVI	Transcriptional regulator
HRD70_05230	ENOG4108WFC	UPF0438 protein yifE
HRD70_05235	ENOG4105C0P	Mg chelatase subunit ChlI
HRD70_05250	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HRD70_05255	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HRD70_05260	ENOG4105C01	Dihydroxy-acid dehydratase
HRD70_05265	ENOG4105C7B	Threonine dehydratase
HRD70_05275	ENOG4105EMY	transcriptional regulator
HRD70_05280	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HRD70_05330	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HRD70_05335	ENOG4105C01	Dihydroxy-acid dehydratase
HRD70_05340	ENOG4108VEV	chaperone
HRD70_05350	ENOG4105CW0	outer membrane usher protein
HRD70_05355	ENOG4105GQR	Chaperone
HRD70_05365	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HRD70_05370	ENOG4105C4R	Atp-dependent dna helicase
HRD70_05375	ENOG4105C9X	ppx gppa phosphatase
HRD70_05390	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HRD70_05395	ENOG4105ESV	Glycosyl transferase, family 4
HRD70_05400	ENOG4105SFE	lipopolysaccharide biosynthesis protein
HRD70_05405	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HRD70_05410	ENOG4108IJ1	Dehydrogenase
HRD70_05415	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HRD70_05420	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HRD70_05425	ENOG4108WJ1	acetyltransferase
HRD70_05430	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRD70_05435	ENOG4105EGZ	biosynthesis protein
HRD70_05440	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
HRD70_05455	ENOG4105C85	amino acid
HRD70_05480	ENOG410601J	HemY protein
HRD70_05485	ENOG4105ECF	c-methyltransferase
HRD70_05490	ENOG41076E6	Uroporphyrinogen-III Synthase
HRD70_05495	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HRD70_05505	ENOG4105XQ6	frataxin-like protein
HRD70_05510	ENOG4105S7Z	(LipO)protein
HRD70_05515	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HRD70_05520	ENOG4105CT0	Protein of unknown function, DUF484
HRD70_05525	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD70_05530	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HRD70_05535	ENOG4105C4R	Atp-dependent dna helicase
HRD70_05545	ENOG4105EQN	UPF0261 protein
HRD70_05565	ENOG4105FR1	rard protein
HRD70_05570	ENOG4108VUY	thioesterase Superfamily protein
HRD70_05575	ENOG4105HDD	phospholipase
HRD70_05580	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HRD70_05590	ENOG410829K	Lysine exporter protein (Lyse ygga)
HRD70_05595	ENOG4108EUD	Lysophospholipase
HRD70_05600	ENOG4105DQF	Hydrolase
HRD70_05605	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HRD70_05610	ENOG4105CXY	transporter
HRD70_05620	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
HRD70_05630	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HRD70_05635	ENOG4108W1V	Lipoprotein
HRD70_05640	ENOG4105EX9	Membrane
HRD70_05645	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HRD70_05655	ENOG4107FS9	Membrane
HRD70_05670	ENOG4105MG3	Membrane
HRD70_05675	ENOG4106H78	methyltransferase
HRD70_05680	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HRD70_05685	ENOG4105CAK	Cell division ATP-binding protein ftsE
HRD70_05690	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HRD70_05710	ENOG4105U59	-acetyltransferase
HRD70_05715	ENOG4105CP9	extracellular ligand-binding receptor
HRD70_05720	ENOG4105C32	Amino acid ABC transporter (Permease)
HRD70_05725	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HRD70_05730	ENOG4105C0Z	ABC transporter
HRD70_05735	ENOG4108IV0	ABC, transporter
HRD70_05770	ENOG4105BZ7	extracellular solute-binding protein family 1
HRD70_05775	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HRD70_05780	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HRD70_05785	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_05790	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HRD70_05795	ENOG4105RK9	auxin efflux carrier
HRD70_05800	ENOG4105EMK	carboxylate amino acid amine transporter
HRD70_05805	ENOG4105DZ2	Transcriptional regulator
HRD70_05810	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HRD70_05815	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HRD70_05820	ENOG4107SXA	Phosphorylase
HRD70_05835	ENOG4108KF1	Membrane
HRD70_05840	ENOG4105CGY	Dna recombination protein
HRD70_05845	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HRD70_05850	ENOG4105JC1	sterol-binding domain protein
HRD70_05855	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HRD70_05860	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HRD70_05865	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HRD70_05870	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HRD70_05880	ENOG4105D52	delta-aminolevulinic acid dehydratase
HRD70_05885	ENOG4105MDZ	Transcriptional activator rfaH
HRD70_05890	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HRD70_05895	ENOG4107QK7	reductase
HRD70_05900	ENOG4105CHU	acetyl-coa acetyltransferase
HRD70_05905	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HRD70_05910	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HRD70_05915	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HRD70_05920	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HRD70_05925	ENOG4108RR8	protoporphyrinogen oxidase
HRD70_05950	ENOG4107QN1	sodium solute
HRD70_05955	ENOG41062QD	Membrane
HRD70_05960	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HRD70_05965	ENOG4105CK2	sodium dicarboxylate symporter
HRD70_05975	ENOG4105BZU	Histidine kinase
HRD70_06005	ENOG4105ZQI	secreted protein
HRD70_06015	ENOG4108SZ7	secretion system effector
HRD70_06020	ENOG4106FZW	pathogenicity island effector protein
HRD70_06075	ENOG4105UQF	type iii secretion
HRD70_06090	ENOG4108JIR	Flagellum-specific ATP synthase
HRD70_06105	ENOG41063Q7	Type III secretion system protein
HRD70_06110	ENOG4108HHI	Type III secretion system protein
HRD70_06115	ENOG41083GP	type iii secretion
HRD70_06120	ENOG4108TN6	type iii secretion
HRD70_06125	ENOG4108IUF	type iii secretion
HRD70_06130	ENOG41066VF	YeeE YedE family protein
HRD70_06145	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD70_06150	ENOG4108S3W	Anti-feci sigma factor, fecr
HRD70_06155	ENOG4105PE1	Receptor
HRD70_06160	ENOG4105CQ0	ABC transporter
HRD70_06165	ENOG4107RAN	Peptidase, M16
HRD70_06170	ENOG4105EGS	Mechanosensitive ion channel
HRD70_06175	ENOG4105E0K	tonB-dependent siderophore receptor
HRD70_06185	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HRD70_06190	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HRD70_06195	ENOG4105EHG	Permease protein
HRD70_06200	ENOG4107R4I	Periplasmic binding protein
HRD70_06205	ENOG4106QJH	hemin transport protein
HRD70_06210	ENOG4107ENK	receptor
HRD70_06215	ENOG4107F3C	Hemin uptake protein
HRD70_06220	ENOG4105CHR	reductase
HRD70_06225	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HRD70_06235	ENOG4105E0K	tonB-dependent siderophore receptor
HRD70_06245	ENOG4108AEY	RNA polymerase sigma factor
HRD70_06265	ENOG4105CDU	Replicative dna helicase
HRD70_06305	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRD70_06370	ENOG4107QJE	Chromosome Partitioning Protein
HRD70_06430	ENOG4107UNZ	domain protein
HRD70_06520	ENOG4108X3P	Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures
HRD70_06535	ENOG4105E3B	Multicopper oxidase
HRD70_06550	ENOG4105GR3	Histidine kinase
HRD70_06555	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRD70_06560	ENOG4108PG2	copper resistance
HRD70_06565	ENOG4105JDN	Copper resistance protein
HRD70_06570	ENOG4105VR0	copper resistance
HRD70_06575	ENOG4105E3B	Multicopper oxidase
HRD70_06590	ENOG4105DR5	peptidase
HRD70_06620	ENOG410624V	efflux system protein
HRD70_06630	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRD70_06660	ENOG4108SIC	Transcriptional regulator
HRD70_06665	ENOG4105BZW	Glycerate kinase
HRD70_06670	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HRD70_06680	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HRD70_06695	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HRD70_06700	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HRD70_06705	ENOG4108ZVF	(LipO)protein
HRD70_06710	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HRD70_06715	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HRD70_06735	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HRD70_06740	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HRD70_06755	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HRD70_06760	ENOG4105EGS	Mechanosensitive ion channel
HRD70_06765	ENOG4105DJ4	phosphatidylserine decarboxylase
HRD70_06770	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HRD70_06775	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HRD70_06795	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HRD70_06800	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HRD70_06810	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HRD70_06815	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HRD70_06820	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HRD70_06825	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HRD70_06830	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HRD70_06835	ENOG4107QJR	hflk protein
HRD70_06840	ENOG4105EPW	hflc protein
HRD70_06850	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HRD70_06855	ENOG4105KPV	Transcriptional regulator
HRD70_06860	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HRD70_06865	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HRD70_06870	ENOG4105CSU	acyl-Coa dehydrogenase
HRD70_06875	ENOG4105WSB	biofilm stress and motility protein A
HRD70_06880	ENOG4108MXZ	Esterase
HRD70_06890	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HRD70_06895	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HRD70_06905	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HRD70_06915	ENOG4105FHY	Opacity-associated protein A
HRD70_06920	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HRD70_06925	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HRD70_06930	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HRD70_06935	ENOG4108UUE	Transcriptional regulator
HRD70_06940	ENOG41061GZ	Protein of unknown function (DUF1107)
HRD70_06945	ENOG4105C37	(CBS) domain
HRD70_06950	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HRD70_06960	ENOG4105MA0	exported protein
HRD70_06965	ENOG4108ZHD	aig2 family
HRD70_06970	ENOG4105F0N	pyrophosphate phospho-hydrolase
HRD70_06975	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_06980	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HRD70_06985	ENOG4105DFU	Cell wall formation (By similarity)
HRD70_07000	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HRD70_07005	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HRD70_07010	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD70_07020	ENOG4105EAH	synthase
HRD70_07035	ENOG4105QYV	Membrane
HRD70_07040	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HRD70_07055	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HRD70_07065	ENOG4105HBR	Rna-binding protein
HRD70_07070	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HRD70_07075	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HRD70_07080	ENOG4105EEI	dihydropteroate synthase
HRD70_07090	ENOG4105NTZ	Preprotein translocase subunit SecG
HRD70_07105	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HRD70_07110	ENOG4105CHV	Transcription elongation factor NusA
HRD70_07115	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HRD70_07120	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HRD70_07125	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HRD70_07135	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HRD70_07150	ENOG4105C1J	atp-dependent rna helicase
HRD70_07155	ENOG4105DEN	Luciferase family
HRD70_07175	ENOG4108YYD	acetyltransferase
HRD70_07180	ENOG41082IR	Excinuclease ABC C subunit domain protein
HRD70_07185	ENOG4105D5Q	Arginine ornithine antiporter
HRD70_07190	ENOG4105CXN	decarboxylase
HRD70_07220	ENOG4105DRS	transport system, permease
HRD70_07235	ENOG4108ZPB	UPF0306 protein
HRD70_07240	ENOG4105K4T	epimerase
HRD70_07245	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
HRD70_07250	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
HRD70_07255	ENOG4105FD8	phosphonate metabolism protein PhnM
HRD70_07260	ENOG4105HRV	phosphonate c-p lyase system protein phnl
HRD70_07265	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
HRD70_07270	ENOG4105FT8	Phosphonate metabolism
HRD70_07275	ENOG4105EKV	Phosphonate metabolism protein
HRD70_07280	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
HRD70_07285	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
HRD70_07290	ENOG4107RJJ	Transcriptional regulator
HRD70_07295	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HRD70_07300	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HRD70_07310	ENOG4108JQ7	(ABC) transporter
HRD70_07315	ENOG4105C3U	ABC transporter
HRD70_07320	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD70_07325	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD70_07335	ENOG4105XEP	YhcH YjgK YiaL family protein
HRD70_07345	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HRD70_07350	ENOG4108MJ3	acetyltransferase
HRD70_07360	ENOG4105MYG	DNA polymerase iii, chi subunit
HRD70_07365	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HRD70_07370	ENOG4108M8S	permease YjgP YjgQ family protein
HRD70_07375	ENOG4108K5H	permease YjgP YjgQ family protein
HRD70_07395	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HRD70_07400	ENOG4105D85	methylase
HRD70_07405	ENOG4105F6A	helicase
HRD70_07410	ENOG4105ECI	YeeC-like protein
HRD70_07475	ENOG4106H6R	UPF0380 protein
HRD70_07480	ENOG4106549	Antirestriction protein
HRD70_07490	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
HRD70_07505	ENOG4105HEI	LysR family (Transcriptional regulator
HRD70_07515	ENOG4105VEV	-acetyltransferase
HRD70_07530	ENOG4108XFH	Transcriptional regulator
HRD70_07535	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
HRD70_07550	ENOG4105CC0	LysR family Transcriptional regulator
HRD70_07565	ENOG4105RI1	glycoprotein receptor
HRD70_07575	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
HRD70_07580	ENOG41061GT	Aldolase
HRD70_07585	ENOG4105D4B	ABC, transporter
HRD70_07590	ENOG4105F5R	ABC transporter
HRD70_07595	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
HRD70_07600	ENOG4105C2J	ABC transporter
HRD70_07605	ENOG4105DKT	Transcriptional regulator
HRD70_07610	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
HRD70_07615	ENOG4105DKP	glycosyl transferase, family 9
HRD70_07625	ENOG4105D5Q	Arginine ornithine antiporter
HRD70_07630	ENOG4105CEU	Arginine dihydrolase
HRD70_07640	ENOG410624X	efflux transporter, rnd family, mfp subunit
HRD70_07645	ENOG4105BZS	acriflavin resistance protein
HRD70_07655	ENOG4105CMT	Dihydroxyacetone kinase
HRD70_07660	ENOG4108UTZ	Dihydroxyacetone kinase
HRD70_07700	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HRD70_07710	ENOG4105GAV	receptor
HRD70_07715	ENOG4105BZU	Histidine kinase
HRD70_07720	ENOG4105YBH	Protein of unknown function (DUF1435)
HRD70_07740	ENOG4105CPC	Aldo Keto reductase
HRD70_07745	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HRD70_07760	ENOG4108WPU	DNA polymerase III subunit psi
HRD70_07765	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HRD70_07770	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HRD70_07775	ENOG4105K3G	Periplasmic Protein
HRD70_07785	ENOG4108NRW	Phospholipase, patatin family
HRD70_07790	ENOG4105EYA	deoxyribonuclease
HRD70_07795	ENOG4105D9N	nucleoside
HRD70_07805	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HRD70_07810	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HRD70_07820	ENOG4105EUP	HipA domain protein
HRD70_07825	ENOG41062Z9	Membrane
HRD70_07830	ENOG4105EAC	phosphoserine phosphatase
HRD70_07835	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HRD70_07850	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HRD70_07855	ENOG4105CIS	alcohol dehydrogenase
HRD70_07865	ENOG4105C5H	ABC transporter
HRD70_07870	ENOG41090EK	ompa motb domain protein
HRD70_07875	ENOG4108KHX	Diguanylate cyclase
HRD70_07880	ENOG4108WS1	
HRD70_07890	ENOG4107SC1	transglycosylase
HRD70_07895	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HRD70_07900	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRD70_07910	ENOG4105UEI	Transcriptional Regulator AraC Family
HRD70_07915	ENOG4108RH0	Crea protein
HRD70_07920	ENOG41065U4	response regulator
HRD70_07935	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HRD70_07945	ENOG4105D1Q	UPF0246 protein
HRD70_07950	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HRD70_07955	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HRD70_07960	ENOG4105CSH	Transporter
HRD70_07970	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HRD70_07980	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HRD70_07985	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HRD70_07990	ENOG41063Z6	transcriptional regulator, lysR family
HRD70_08010	ENOG4105DTN	riboflavin biosynthesis protein ribF
HRD70_08015	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HRD70_08020	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HRD70_08025	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HRD70_08030	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HRD70_08035	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HRD70_08045	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HRD70_08050	ENOG4105N14	lysine exporter protein LysE YggA
HRD70_08055	ENOG4105DWK	Membrane
HRD70_08065	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HRD70_08070	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HRD70_08075	ENOG4105NWN	ApaG protein
HRD70_08085	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HRD70_08095	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HRD70_08105	ENOG4105D3G	Pseudouridine synthase
HRD70_08110	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HRD70_08115	ENOG4105CQ2	DNA polymerase
HRD70_08120	ENOG4108KF1	Membrane
HRD70_08130	ENOG4106SMU	thiamine transporter membrane protein
HRD70_08135	ENOG4105DP9	ABC transporter
HRD70_08145	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HRD70_08150	ENOG4105F1A	Pyruvate formate-lyase
HRD70_08160	ENOG4105S8Q	sugar efflux transporter
HRD70_08165	ENOG4105C0F	tryptophanase EC 4.1.99.1
HRD70_08180	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HRD70_08185	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HRD70_08190	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HRD70_08200	ENOG41064T2	transcriptional regulator, lysR family
HRD70_08205	ENOG4108IQE	Amp-dependent synthetase and ligase
HRD70_08210	ENOG4105C7K	acetolactate synthase
HRD70_08215	ENOG4108ZP8	Acetolactate synthase small subunit
HRD70_08220	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HRD70_08230	ENOG4108V6E	Cell division protein mraZ
HRD70_08235	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HRD70_08240	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HRD70_08245	ENOG4105CJN	penicillin-binding protein
HRD70_08250	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HRD70_08255	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HRD70_08260	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HRD70_08270	ENOG4105CNI	cell division protein FtsW
HRD70_08275	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HRD70_08280	ENOG4105DFU	Cell wall formation (By similarity)
HRD70_08290	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HRD70_08295	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HRD70_08300	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HRD70_08315	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
HRD70_08320	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HRD70_08325	ENOG4105M6F	mutator MutT protein
HRD70_08330	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HRD70_08345	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HRD70_08350	ENOG4105D7Q	type ii secretion system
HRD70_08355	ENOG4107QHF	type ii secretion system protein e
HRD70_08360	ENOG4108ZUW	Major pilin subunit
HRD70_08365	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HRD70_08375	ENOG4106A72	regulatory protein AmpE
HRD70_08380	ENOG4105C85	amino acid
HRD70_08385	ENOG41073TP	transcriptional regulator
HRD70_08390	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HRD70_08395	ENOG4107QSN	dihydrolipoamide acetyltransferase
HRD70_08400	ENOG4107QN2	dihydrolipoyl dehydrogenase
HRD70_08415	ENOG4107RNH	Outer membrane receptor FepA
HRD70_08420	ENOG4107QIJ	Aconitate hydratase 2
HRD70_08425	ENOG4108ZIG	UPF0231 protein
HRD70_08430	ENOG4105RPH	Inner membrane protein YddG
HRD70_08445	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HRD70_08450	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HRD70_08455	ENOG4108ZRK	uncharacterized protein yacC
HRD70_08460	ENOG4105E3B	Multicopper oxidase
HRD70_08470	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HRD70_08475	ENOG41077A9	carbonic anhydrase
HRD70_08480	ENOG4105DA5	(ABC) transporter
HRD70_08485	ENOG4105E3A	(ABC) transporter
HRD70_08490	ENOG4107BJW	polysaccharide deacetylase
HRD70_08495	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HRD70_08500	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HRD70_08505	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HRD70_08510	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HRD70_08515	ENOG4105DJ0	Poly(A) Polymerase
HRD70_08525	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRD70_08530	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HRD70_08535	ENOG4107XID	2'-5' rna ligase
HRD70_08540	ENOG4105CQ7	ATP-dependent helicase
HRD70_08545	ENOG4105BZ4	penicillin-binding protein
HRD70_08550	ENOG4105E0A	ABC, transporter
HRD70_08555	ENOG4105J76	Periplasmic binding protein
HRD70_08560	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HRD70_08570	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HRD70_08580	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HRD70_08590	ENOG4105EN6	Membrane
HRD70_08600	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HRD70_08605	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HRD70_08610	ENOG4105C0H	protease
HRD70_08615	ENOG4105BZU	Histidine kinase
HRD70_08625	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRD70_08630	ENOG4105DXN	mazG family
HRD70_08635	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HRD70_08640	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HRD70_08665	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HRD70_08670	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HRD70_08675	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HRD70_08680	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HRD70_08685	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HRD70_08690	ENOG4108MXK	alkaline phosphatase isozyme conversion
HRD70_08695	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRD70_08700	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HRD70_08705	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HRD70_08710	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HRD70_08715	ENOG4105N0Z	inner membrane protein ygbE
HRD70_08725	ENOG4105DRP	amino acid AbC transporter
HRD70_08730	ENOG4106PMH	Extracellular solute-binding protein family 3
HRD70_08735	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HRD70_08745	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HRD70_08750	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HRD70_08755	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HRD70_08760	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HRD70_08765	ENOG4108K5P	(LipO)protein
HRD70_08770	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD70_08775	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HRD70_08800	ENOG4106PG1	outer membrane usher protein
HRD70_08805	ENOG4108FZ9	Chaperone
HRD70_08820	ENOG4105NEV	Fimbrial
HRD70_08825	ENOG4105H8W	Fimbrial protein
HRD70_08850	ENOG4108JJA	ABC, transporter
HRD70_08855	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HRD70_08860	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HRD70_08865	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HRD70_08870	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD70_08885	ENOG4105CHR	reductase
HRD70_08890	ENOG4105E89	ABC transporter
HRD70_08900	ENOG4105CA0	peroxidase
HRD70_08915	ENOG4105BZC	d-serine deaminase
HRD70_08920	ENOG4106TNF	Periplasmic binding protein
HRD70_08925	ENOG4105E5Q	amino acid AbC transporter
HRD70_08930	ENOG4105E5Q	amino acid AbC transporter
HRD70_08935	ENOG4108JEH	abc transporter atp-binding protein
HRD70_08940	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HRD70_08945	ENOG4105EIG	urea carboxylase-associated protein 1
HRD70_08960	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HRD70_08965	ENOG4105YVS	arsR family transcriptional regulator
HRD70_08970	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
HRD70_08975	ENOG4105F3R	pts system mannose fructose sorbose family iid
HRD70_08980	ENOG4105ETZ	PTS System
HRD70_08985	ENOG4105KPI	PTS system sorbose subfamily IIB component
HRD70_08990	ENOG4108XCU	pts system
HRD70_08995	ENOG4105CHR	reductase
HRD70_09000	ENOG4105DKT	Transcriptional regulator
HRD70_09025	ENOG4108IV0	ABC, transporter
HRD70_09030	ENOG4108IUZ	ABC transporter
HRD70_09035	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HRD70_09040	ENOG4105C32	Amino acid ABC transporter (Permease)
HRD70_09050	ENOG4107GFK	fumarate
HRD70_09055	ENOG4107EDW	L-fucose operon activator
HRD70_09060	ENOG4105NWF	RbsD or FucU transport
HRD70_09065	ENOG4105CMG	Carbohydrate kinase
HRD70_09070	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
HRD70_09075	ENOG4105EDR	glucose galactose transporter
HRD70_09080	ENOG4107W7X	Aldolase
HRD70_09085	ENOG4105C0A	alcohol dehydrogenase
HRD70_09090	ENOG4107QY8	reductase
HRD70_09095	ENOG4105QAX	Iron-sulfur
HRD70_09100	ENOG4107KGK	dmso reductase anchor subunit
HRD70_09105	ENOG4108NEM	leader-binding protein dmsD
HRD70_09120	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HRD70_09125	ENOG4105Y3E	Modulates RecA activity (By similarity)
HRD70_09130	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HRD70_09160	ENOG4107VXZ	Hydrolase
HRD70_09165	ENOG4105W39	Membrane
HRD70_09170	ENOG4105D9M	gamma-glutamylcysteine synthetase
HRD70_09175	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HRD70_09180	ENOG4108JU6	CBS domain protein
HRD70_09185	ENOG4106KVJ	cytochrome C assembly protein
HRD70_09190	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HRD70_09200	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HRD70_09205	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HRD70_09210	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HRD70_09215	ENOG4108NE3	Salt-induced outer membrane protein
HRD70_09220	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HRD70_09225	ENOG4108NEV	two component transcriptional regulator, LytTR family
HRD70_09230	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD70_09240	ENOG4105CQC	Prephenate dehydratase
HRD70_09245	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HRD70_09250	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRD70_09255	ENOG4105C34	Pseudouridine synthase
HRD70_09260	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HRD70_09265	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD70_09295	ENOG4105CV8	reductase
HRD70_09300	ENOG4105HEI	LysR family (Transcriptional regulator
HRD70_09305	ENOG4105F27	Major Facilitator
HRD70_09310	ENOG4107NA1	Endonuclease Exonuclease phosphatase
HRD70_09315	ENOG4105E9H	Lytic Murein transglycosylase
HRD70_09320	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HRD70_09325	ENOG4105D1A	Methyltransferase
HRD70_09330	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRD70_09335	ENOG4107RZZ	dna polymerase iii epsilon subunit
HRD70_09345	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HRD70_09365	ENOG4105GIJ	Glycine betaine
HRD70_09370	ENOG4108HQS	Glycine betaine
HRD70_09375	ENOG4108IJ7	Glycine betaine
HRD70_09380	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD70_09390	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HRD70_09395	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
HRD70_09400	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HRD70_09410	ENOG4105TNS	Conserved Protein
HRD70_09420	ENOG4105F9N	Major Facilitator Superfamily
HRD70_09425	ENOG4108WMJ	Protein of unknown function (DUF2002)
HRD70_09430	ENOG4108SAJ	Protein of unknown function (DUF1198)
HRD70_09440	ENOG4105VEQ	Cold shock protein
HRD70_09470	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD70_09480	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
HRD70_09485	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HRD70_09490	ENOG4105KI2	Urea amidohydrolase subunit beta
HRD70_09495	ENOG4105CQM	Urea amidohydrolase subunit alpha
HRD70_09500	ENOG4108VDS	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HRD70_09510	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HRD70_09515	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HRD70_09530	ENOG4105XXV	Acid-resistance protein
HRD70_09535	ENOG4107SVH	Potassium channel protein
HRD70_09550	ENOG4105CPC	Aldo Keto reductase
HRD70_09555	ENOG4105D8V	Glucose sorbosone dehydrogenase
HRD70_09560	ENOG4105VZJ	PTS System
HRD70_09565	ENOG4105CK1	PTS System
HRD70_09570	ENOG4105CS2	ec 3.2.1.21
HRD70_09575	ENOG4105VCP	PTS System
HRD70_09580	ENOG4105EZV	Transcriptional regulator
HRD70_09585	ENOG410901P	UPF0249 protein
HRD70_09595	ENOG41090KR	LysR family transcriptional Regulator
HRD70_09605	ENOG4105E6M	Sulphatase-modifying factor protein
HRD70_09615	ENOG4107R39	(ABC) transporter
HRD70_09660	ENOG4105W8I	Transcriptional regulator
HRD70_09665	ENOG4105KD7	acetyltransferase
HRD70_09675	ENOG4108X3P	Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures
HRD70_09680	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
HRD70_09685	ENOG4108XS9	dna repair protein
HRD70_09690	ENOG4106H6R	UPF0380 protein
HRD70_09715	ENOG4105H5P	transposase
HRD70_09720	ENOG4108P8R	
HRD70_09725	ENOG410679B	prophage CP4-57 regulatory protein alpA
HRD70_09760	ENOG4105DFP	Integrase
HRD70_09770	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HRD70_09775	ENOG4108Z1B	Cyclase dehydrase
HRD70_09785	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD70_09790	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HRD70_09795	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HRD70_09800	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HRD70_09805	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HRD70_09810	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HRD70_09830	ENOG4105C1J	atp-dependent rna helicase
HRD70_09835	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HRD70_09840	ENOG4108IYU	L-aspartate oxidase
HRD70_09850	ENOG41069PW	sigma-e factor negative regulatory protein
HRD70_09860	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HRD70_09870	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HRD70_09875	ENOG4105C3F	Signal peptidase i
HRD70_09885	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HRD70_09890	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HRD70_09895	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HRD70_09900	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HRD70_09905	ENOG4107EFN	gluconate transport system permease 3
HRD70_09910	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HRD70_09915	ENOG4106G6Q	Transcriptional regulator
HRD70_09925	ENOG4105HYY	HAD superfamily (Subfamily IF) hydrolase, YfhB
HRD70_09935	ENOG4108Z6B	deaminase
HRD70_09940	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HRD70_09955	ENOG4107WP9	Histidine kinase
HRD70_09960	ENOG4108SKK	alpha helix protein
HRD70_09965	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRD70_09970	ENOG4105C4K	Nad synthetase
HRD70_09975	ENOG4108YZA	Nitrogen regulatory protein pii
HRD70_09980	ENOG4105RMW	regulation of transcription, DNA-dependent
HRD70_09985	ENOG4108M21	
HRD70_09990	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HRD70_09995	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HRD70_10000	ENOG4105D8G	Major Facilitator superfamily
HRD70_10005	ENOG4108MN2	Stationary phase inducible protein CsiE
HRD70_10010	ENOG41065CD	Exported protein
HRD70_10015	ENOG4105D7X	high-affinity nickel-transporter
HRD70_10020	ENOG4105ECY	inositol monophosphatase
HRD70_10025	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HRD70_10030	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HRD70_10035	ENOG4105C3J	Cysteine desulfurase
HRD70_10040	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HRD70_10050	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HRD70_10055	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HRD70_10060	ENOG4108ZIT	Ferredoxin, 2FE-2S
HRD70_10065	ENOG4105WVQ	Fe-S assembly protein IscX
HRD70_10075	ENOG4105YYA	enhanced serine sensitivity protein SseB
HRD70_10080	ENOG4108MGN	ATP-binding component of a transport system
HRD70_10085	ENOG4105DN3	alpha-2-macroglobulin domain protein
HRD70_10090	ENOG4108JQB	penicillin-binding protein 1C
HRD70_10105	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HRD70_10115	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HRD70_10120	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HRD70_10125	ENOG4105CUT	histidyl-tRNA synthetase
HRD70_10130	ENOG4105N21	Membrane
HRD70_10135	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD70_10140	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HRD70_10150	ENOG4105VPD	cellular component movement
HRD70_10155	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HRD70_10160	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HRD70_10165	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HRD70_10200	ENOG4105DWF	phosphomethylpyrimidine kinase
HRD70_10210	ENOG4108ZGU	inhibitor of vertebrate lysozyme
HRD70_10220	ENOG410804X	Transcriptional regulator
HRD70_10225	ENOG4105J92	DNA-binding transcriptional activator GutM
HRD70_10230	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
HRD70_10235	ENOG4105VI0	Pts system, glucitol sorbitol-specific
HRD70_10240	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HRD70_10245	ENOG410787A	Pts system, glucitol sorbitol-specific
HRD70_10250	ENOG4107TE5	Lipid kinase
HRD70_10255	ENOG4105CFP	Peptidase U32
HRD70_10260	ENOG4105KWI	UPF0339 protein
HRD70_10265	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD70_10270	ENOG4105EB3	Histidine kinase
HRD70_10275	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD70_10280	ENOG4105BZS	acriflavin resistance protein
HRD70_10290	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HRD70_10295	ENOG4105R8A	Heat shock protein
HRD70_10300	ENOG4105BZU	Histidine kinase
HRD70_10305	ENOG4105CJW	magnesium transporter
HRD70_10315	ENOG4105C9X	ppx gppa phosphatase
HRD70_10320	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HRD70_10325	ENOG4105C8U	phosphate abc transporter
HRD70_10330	ENOG4105E2Z	phosphate ABC transporter (Permease
HRD70_10340	ENOG4108C80	FliB family
HRD70_10345	ENOG4108MK9	spermidine N(1)-acetyltransferase
HRD70_10350	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HRD70_10355	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HRD70_10360	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HRD70_10365	ENOG4105C2W	permease
HRD70_10370	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HRD70_10375	ENOG4105K89	arsenate reductase
HRD70_10380	ENOG4105ERG	peptidase m48, ste24p
HRD70_10385	ENOG4105C02	permease
HRD70_10390	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRD70_10395	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HRD70_10400	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HRD70_10405	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD70_10410	ENOG4105C8V	SAICAR synthetase
HRD70_10415	ENOG4105CGZ	zinc metallopeptidase
HRD70_10420	ENOG4108VMM	UPF0756 membrane protein
HRD70_10425	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HRD70_10430	ENOG4106KED	esterase YpfH
HRD70_10435	ENOG4105XYK	UPF0370 protein
HRD70_10445	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HRD70_10450	ENOG4105KUZ	arsenate reductase
HRD70_10625	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
HRD70_10630	ENOG4107Z33	ABC transporter, permease
HRD70_10635	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_10645	ENOG4105BZS	acriflavin resistance protein
HRD70_10655	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD70_10665	ENOG41061Q0	Assembly protein for periplasmic nitrate reductase
HRD70_10670	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HRD70_10675	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
HRD70_10680	ENOG4105CUW	cytochrome C-TYPE protein
HRD70_10685	ENOG4107VIJ	nudix hydrolase
HRD70_10690	ENOG4105C6K	Malic enzyme
HRD70_10695	ENOG4108UPT	UPF0178 protein
HRD70_10700	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HRD70_10705	ENOG4108R6G	acetyltransferase
HRD70_10715	ENOG4105F27	Major Facilitator
HRD70_10720	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HRD70_10725	ENOG4105C2J	ABC transporter
HRD70_10730	ENOG4105CNN	ABC, transporter
HRD70_10735	ENOG4108NQD	
HRD70_10750	ENOG4105KHC	sulfurtransferase
HRD70_10755	ENOG4105CHR	reductase
HRD70_10765	ENOG4105H4F	exported protein
HRD70_10770	ENOG4105E7K	(LipO)protein
HRD70_10775	ENOG4105EZR	dyp-type peroxidase family protein
HRD70_10795	ENOG4108R66	Conserved Protein
HRD70_10800	ENOG4105QEK	Transcriptional regulator
HRD70_10810	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HRD70_10815	ENOG4108I5D	sulfate abc transporter
HRD70_10820	ENOG4105ECW	sulfate abc transporter
HRD70_10830	ENOG4105C6T	cysteine synthase
HRD70_10850	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HRD70_10855	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD70_10860	ENOG4105E0F	Histidine kinase
HRD70_10865	ENOG4105C5Y	PTS System
HRD70_10870	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HRD70_10880	ENOG4105C6T	cysteine synthase
HRD70_10885	ENOG4105EXN	Sulfate transport protein CysZ
HRD70_10895	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HRD70_10900	ENOG4105VRT	cytoplasmic protein
HRD70_10925	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HRD70_10970	ENOG4105D9N	nucleoside
HRD70_10975	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HRD70_10985	ENOG4105CPC	Aldo Keto reductase
HRD70_10990	ENOG4107RA9	decarboxylase
HRD70_10995	ENOG4105C5Q	Transcriptional regulator
HRD70_11005	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HRD70_11010	ENOG4105FCD	Major Facilitator
HRD70_11015	ENOG4105DY9	regulatoR
HRD70_11020	ENOG4108HRK	Histidine kinase
HRD70_11025	ENOG41072TH	Protein of unknown function (DUF1479)
HRD70_11035	ENOG4105CHM	Aminotransferase
HRD70_11040	ENOG4108VKM	cytochrome b561
HRD70_11055	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HRD70_11085	ENOG4107KGK	dmso reductase anchor subunit
HRD70_11090	ENOG4105QAX	Iron-sulfur
HRD70_11095	ENOG4107QY8	reductase
HRD70_11105	ENOG4105E82	cytochrome subunit of dehydrogenase
HRD70_11110	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_11125	ENOG4105CVE	Lytic murein transglycosylase
HRD70_11130	ENOG4105CUB	amino acid
HRD70_11155	ENOG4105DHJ	ABC, transporter
HRD70_11170	ENOG4105DS1	cytochrome b561
HRD70_11175	ENOG4108YYC	ycei family
HRD70_11180	ENOG4105DDV	Transcriptional regulator (LacI family
HRD70_11185	ENOG4105C5Y	PTS System
HRD70_11190	ENOG4105CS2	ec 3.2.1.21
HRD70_11200	ENOG4105NTW	Transcriptional regulator
HRD70_11215	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HRD70_11220	ENOG4105D01	(LipO)protein
HRD70_11225	ENOG4108UMI	ABC transporter, permease
HRD70_11230	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_11240	ENOG4105S64	Formate nitrite transporter
HRD70_11250	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HRD70_11255	ENOG41060IM	Heme exporter protein
HRD70_11260	ENOG4105X3C	heme exporter protein
HRD70_11265	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HRD70_11270	ENOG4105DA4	cytochrome c-type biogenesis protein
HRD70_11275	ENOG4107QX9	Thiol disulfide interChange protein
HRD70_11280	ENOG4108M1T	Cytochrome c-type biogenesis protein
HRD70_11285	ENOG4105KWW	Biogenesis protein
HRD70_11290	ENOG410903C	(LipO)protein
HRD70_11305	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HRD70_11310	ENOG4105KZW	UPF0381 protein
HRD70_11315	ENOG4105CHU	acetyl-coa acetyltransferase
HRD70_11320	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HRD70_11325	ENOG4108BY2	phosphohistidine phosphatase
HRD70_11330	ENOG4108DG9	Smr protein MutS2
HRD70_11335	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HRD70_11340	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HRD70_11345	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
HRD70_11350	ENOG4105EJ9	Membrane
HRD70_11355	ENOG4108BPE	-transporting atpase
HRD70_11360	ENOG4105MH2	YfcL protein
HRD70_11365	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HRD70_11370	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD70_11390	ENOG4105VCP	PTS System
HRD70_11395	ENOG4105CS2	ec 3.2.1.21
HRD70_11400	ENOG4105CK1	PTS System
HRD70_11410	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_11415	ENOG4105D6F	Phosphatase
HRD70_11420	ENOG4105F4P	)-transporter
HRD70_11425	ENOG4106WZ1	flagella biosynthesis regulator
HRD70_11430	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HRD70_11440	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRD70_11445	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HRD70_11455	ENOG410631K	Membrane
HRD70_11465	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HRD70_11470	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HRD70_11480	ENOG4105DQR	SNARE associated Golgi
HRD70_11485	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HRD70_11490	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HRD70_11495	ENOG4108S3P	Sporulation domain protein
HRD70_11500	ENOG4105E96	Colicin v production protein
HRD70_11505	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HRD70_11510	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HRD70_11515	ENOG4105E89	ABC transporter
HRD70_11520	ENOG4105DSP	amino acid AbC transporter
HRD70_11525	ENOG4106YG3	ABC transporter
HRD70_11530	ENOG4108JEH	abc transporter atp-binding protein
HRD70_11535	ENOG4105ECP	epimerase
HRD70_11545	ENOG4108RE9	Phosphodiesterase
HRD70_11550	ENOG4105PTV	Nudix Hydrolase
HRD70_11555	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HRD70_11565	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
HRD70_11570	ENOG4107P2S	Transcriptional regulator
HRD70_11575	ENOG4105C6K	Malic enzyme
HRD70_11585	ENOG4105PQ6	UPF0208 membrane protein
HRD70_11590	ENOG4105XWI	UPF0304 protein
HRD70_11595	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HRD70_11600	ENOG4107QWE	)-transporter
HRD70_11605	ENOG4105DK2	UPF0207 protein
HRD70_11615	ENOG4105CHM	Aminotransferase
HRD70_11625	ENOG4107NQ8	LysR family Transcriptional regulator
HRD70_11630	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HRD70_11635	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD70_11640	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD70_11650	ENOG4107QIZ	NADH dehydrogenase
HRD70_11655	ENOG4108IEH	NADH dehydrogenase subunit g
HRD70_11660	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HRD70_11665	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD70_11670	ENOG4107UFS	subunit j
HRD70_11675	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD70_11680	ENOG4105D65	subunit l
HRD70_11685	ENOG4105C8S	subunit m
HRD70_11690	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD70_11710	ENOG4108UQ5	membrane protein YcdZ
HRD70_11720	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HRD70_11725	ENOG4105CHR	reductase
HRD70_11730	ENOG4105K2J	Transcriptional regulator
HRD70_11735	ENOG4105C5I	Dehydrogenase
HRD70_11745	ENOG41090KN	UPF0303 protein
HRD70_11750	ENOG4105C01	Dihydroxy-acid dehydratase
HRD70_11755	ENOG4105TNS	Conserved Protein
HRD70_11760	ENOG4105E4F	Isochorismate synthase
HRD70_11765	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HRD70_11770	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HRD70_11775	ENOG4108IPT	Naphthoate synthase
HRD70_11780	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HRD70_11785	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD70_11790	ENOG4105CH6	catalase
HRD70_11795	ENOG4108UII	YfaZ family
HRD70_11800	ENOG4105E0U	tyrosine-specific transport protein
HRD70_11810	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
HRD70_11815	ENOG4105XPH	Ferredoxin
HRD70_11820	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD70_11825	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD70_11830	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HRD70_11835	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD70_11840	ENOG4105BZU	Histidine kinase
HRD70_11845	ENOG41068CG	regulatoR
HRD70_11850	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
HRD70_11855	ENOG4106UW1	Major Facilitator superfamily
HRD70_11865	ENOG4105CPQ	Dehydrogenase
HRD70_11890	ENOG4107R6D	beta-lactam binding protein AmpH
HRD70_11905	ENOG4105CT4	transporter
HRD70_11915	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_11925	ENOG4105Y50	Virulence Protein
HRD70_11935	ENOG4105HRS	Antitermination protein
HRD70_11945	ENOG4105KUS	lysozyme
HRD70_11970	ENOG4105TKZ	Tail Sheath
HRD70_12010	ENOG4108T86	baseplate J family protein
HRD70_12025	ENOG4105UZW	Tail fiber assembly protein
HRD70_12030	ENOG4105HX0	Transcriptional regulator
HRD70_12035	ENOG4105C5Y	PTS System
HRD70_12040	ENOG4105CS2	ec 3.2.1.21
HRD70_12070	ENOG4105E68	Sulfatase
HRD70_12075	ENOG4105PAN	UPF0352 protein
HRD70_12080	ENOG4106V8H	Nucleoid-associated protein
HRD70_12090	ENOG4105CFI	type iii restriction protein res subunit
HRD70_12095	ENOG4105I08	Pseudouridine synthase
HRD70_12100	ENOG4105C2C	drug resistance transporter, Bcr CflA
HRD70_12105	ENOG4105HG6	
HRD70_12110	ENOG4108JQ5	ABC transporter
HRD70_12115	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HRD70_12120	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HRD70_12125	ENOG4105E43	Extracellular solute-binding protein, family 5
HRD70_12130	ENOG4105CXC	rtn protein
HRD70_12135	ENOG4107TT5	NLP P60 protein
HRD70_12140	ENOG41076MN	Phosphoesterase, PA-phosphatase related
HRD70_12145	ENOG4105CKI	cobalamin synthesis protein
HRD70_12150	ENOG4107YCY	Transcriptional regulator
HRD70_12155	ENOG4105DEI	Mannitol dehydrogenase
HRD70_12165	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HRD70_12175	ENOG4105KRS	Proteinase inhibitor
HRD70_12180	ENOG4107QY8	reductase
HRD70_12185	ENOG4105CUW	cytochrome C-TYPE protein
HRD70_12195	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HRD70_12200	ENOG4105DE4	1-phosphofructokinase
HRD70_12205	ENOG4105DM4	PTS System
HRD70_12210	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HRD70_12215	ENOG4105HMI	Membrane
HRD70_12225	ENOG4105DUM	transcriptional regulator, lysR family
HRD70_12230	ENOG4108IQI	permease
HRD70_12235	ENOG4105EHG	Permease protein
HRD70_12245	ENOG4105D05	Receptor
HRD70_12250	ENOG4108TGY	Glutathione S-transferase
HRD70_12265	ENOG4105D01	(LipO)protein
HRD70_12275	ENOG4108UMI	ABC transporter, permease
HRD70_12280	ENOG4105C28	cystathionine
HRD70_12290	ENOG4105DZ1	carboxypeptidase
HRD70_12295	ENOG4105EJQ	L-serine dehydratase
HRD70_12300	ENOG4105C44	Serine transporter
HRD70_12305	ENOG4107FB0	transcriptional regulator DeoR family
HRD70_12310	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HRD70_12315	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HRD70_12325	ENOG4105D0C	transport protein
HRD70_12330	ENOG41090BQ	Glutaredoxin
HRD70_12335	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
HRD70_12340	ENOG4108RMJ	sensory transduction regulator
HRD70_12345	ENOG4107RUE	extracellular solute-binding protein family 1
HRD70_12350	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_12355	ENOG4105F38	ABC transporter, permease
HRD70_12360	ENOG4105D38	putrescine abc transporter
HRD70_12365	ENOG4105RBQ	inner membrane protein ybjO
HRD70_12370	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HRD70_12375	ENOG4106TNF	Periplasmic binding protein
HRD70_12380	ENOG4105DMR	ABC, transporter
HRD70_12385	ENOG4105GBT	ABC transporter
HRD70_12390	ENOG4106PMH	Extracellular solute-binding protein family 3
HRD70_12395	ENOG4105E5Z	arginine transporter ATP-binding subunit
HRD70_12400	ENOG41064MM	(LipO)protein
HRD70_12410	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HRD70_12415	ENOG4105CGD	Nad-dependent epimerase dehydratase
HRD70_12420	ENOG4105C5W	Aldolase
HRD70_12430	ENOG4105C7K	acetolactate synthase
HRD70_12435	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HRD70_12440	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HRD70_12445	ENOG4105DWU	Membrane
HRD70_12450	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HRD70_12455	ENOG4108MJ5	VirK protein
HRD70_12460	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HRD70_12470	ENOG4105VEQ	Cold shock protein
HRD70_12475	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HRD70_12480	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD70_12490	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HRD70_12495	ENOG4108JJ8	(ABC) transporter
HRD70_12500	ENOG4108JJ9	ABC, transporter
HRD70_12505	ENOG4105C3M	thioredoxin reductase
HRD70_12510	ENOG4105EW9	transcriptional regulator AsnC family
HRD70_12515	ENOG4105CNU	cell division protein FtsK
HRD70_12520	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HRD70_12525	ENOG4105D1H	recombination factor protein RarA
HRD70_12530	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HRD70_12535	ENOG4108ISG	Major Facilitator
HRD70_12540	ENOG4105F1A	Pyruvate formate-lyase
HRD70_12545	ENOG4105C6N	Formate acetyltransferase
HRD70_12550	ENOG4105TMB	Formate nitrite transporter
HRD70_12555	ENOG4105DDY	UPF0142 protein ycaO
HRD70_12560	ENOG4105HDK	L-asparaginase
HRD70_12565	ENOG4107VMU	Membrane
HRD70_12570	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HRD70_12575	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HRD70_12580	ENOG4105CAT	Cytidine monophosphate kinase
HRD70_12585	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HRD70_12595	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HRD70_12605	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HRD70_12610	ENOG4105E32	cytoplasmic protein
HRD70_12615	ENOG4105VEQ	Cold shock protein
HRD70_12620	ENOG4105W49	UPF0434 protein
HRD70_12625	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HRD70_12630	ENOG4107VR7	transferase activity, transferring phosphorus-containing groups
HRD70_12635	ENOG4107S90	membrAne
HRD70_12640	ENOG4106371	Methyltransferase
HRD70_12645	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HRD70_12655	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HRD70_12660	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HRD70_12665	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HRD70_12670	ENOG4105C5X	domain protein
HRD70_12675	ENOG4105BZU	Histidine kinase
HRD70_12680	ENOG4105CGF	Aromatic amino acid aminotransferase
HRD70_12690	ENOG4105C5S	asparaginyl-tRNA synthetase
HRD70_12695	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HRD70_12700	ENOG4105CD8	aminopeptidase N
HRD70_12705	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HRD70_12710	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HRD70_12715	ENOG4105QVC	MOSC domain-containing protein
HRD70_12720	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HRD70_12725	ENOG4105C5H	ABC transporter
HRD70_12730	ENOG4105F1S	paraquat-inducible protein a
HRD70_12735	ENOG4105DY2	Paraquat-inducible protein b
HRD70_12740	ENOG4108Q2G	(LipO)protein
HRD70_12745	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HRD70_12750	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD70_12760	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HRD70_12765	ENOG4105DAN	ATP-dependent protease
HRD70_12770	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HRD70_12780	ENOG4108ZD2	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity)
HRD70_12790	ENOG4105EM2	membrane
HRD70_12795	ENOG410901E	Membrane
HRD70_12800	ENOG41088T4	Helicase IV
HRD70_12805	ENOG4108Z5K	methylglyoxal synthase
HRD70_12815	ENOG4105K4P	CoA-binding domain protein
HRD70_12820	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
HRD70_12825	ENOG4105DR4	Methyltransferase
HRD70_12835	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HRD70_12840	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HRD70_12855	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
HRD70_12860	ENOG4108X3P	Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures
HRD70_12870	ENOG4105W5Q	DNA repair protein (RadC
HRD70_12875	ENOG4106549	Antirestriction protein
HRD70_12880	ENOG4106H6R	UPF0380 protein
HRD70_12930	ENOG41085W3	Transposase
HRD70_12975	ENOG4108ZHR	arsR family transcriptional regulator
HRD70_12995	ENOG4105EQR	Transposase IS116 IS110 IS902
HRD70_13000	ENOG4108JJA	ABC, transporter
HRD70_13005	ENOG4108MBX	Secretion Protein
HRD70_13020	ENOG4105H5P	transposase
HRD70_13025	ENOG4108P8R	
HRD70_13030	ENOG410679B	prophage CP4-57 regulatory protein alpA
HRD70_13060	ENOG4107QTH	restriction modification system DNA specificity domain
HRD70_13075	ENOG4105DFP	Integrase
HRD70_13080	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HRD70_13085	ENOG4107IIZ	CRISPR-associated helicase, Cas3
HRD70_13090	ENOG4105ENG	CRISPR-associated protein, Csy1 family
HRD70_13095	ENOG4105DZX	CRISPR-associated protein, Csy2 family
HRD70_13100	ENOG4105M6W	Crispr-associated protein, Csy3 family
HRD70_13110	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HRD70_13115	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
HRD70_13120	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD70_13125	ENOG4105DVI	reductase, NrfD
HRD70_13130	ENOG4105DA4	cytochrome c-type biogenesis protein
HRD70_13135	ENOG4107QX9	Thiol disulfide interChange protein
HRD70_13145	ENOG4108W0S	formate-dependent nitrite reductase complex
HRD70_13155	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HRD70_13170	ENOG4105DJ9	glucan biosynthesis protein
HRD70_13175	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HRD70_13180	ENOG4105NAC	(LipO)protein
HRD70_13195	ENOG4105C26	Dehydrogenase
HRD70_13200	ENOG410642W	LysR family Transcriptional regulator
HRD70_13205	ENOG4105DUX	Transporter
HRD70_13210	ENOG4105C6X	Major Facilitator
HRD70_13215	ENOG4108VGI	doxx family
HRD70_13220	ENOG4105D1S	lipid A biosynthesis
HRD70_13225	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HRD70_13230	ENOG4106AFQ	Histidine kinase
HRD70_13235	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD70_13240	ENOG4106WHD	Tetrathionate reductase
HRD70_13245	ENOG4105DB1	molybdopterin oxidoreductase
HRD70_13260	ENOG4105DSF	transport protein
HRD70_13280	ENOG4105PVA	Biofilm formation regulatory protein BssS
HRD70_13290	ENOG4105EKE	dihydroorotase
HRD70_13295	ENOG41067V3	Antibiotic biosynthesis monooxygenase
HRD70_13300	ENOG4107QQB	Ribonuclease E
HRD70_13300	ENOG4107QQB	Ribonuclease E
HRD70_13305	ENOG4105EI2	Pseudouridine synthase
HRD70_13315	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HRD70_13320	ENOG4105VGS	50s ribosomal protein l32
HRD70_13325	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HRD70_13335	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HRD70_13340	ENOG4105CHR	reductase
HRD70_13350	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD70_13355	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HRD70_13360	ENOG4105HHA	aminodeoxychorismate lyase
HRD70_13365	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HRD70_13370	ENOG4107QRG	dna polymerase iii
HRD70_13375	ENOG4105F8V	Hydrolase, tatD family
HRD70_13380	ENOG4105CI1	PTS System
HRD70_13415	ENOG4105F9E	Shikimate 5-dehydrogenase
HRD70_13420	ENOG4105K59	histidine triad (HIT) protein
HRD70_13425	ENOG41090DQ	Lipoprotein
HRD70_13430	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
HRD70_13445	ENOG4105D0Y	UPF0227 protein
HRD70_13450	ENOG4105CEP	NADH dehydrogenase
HRD70_13465	ENOG4107MBR	17 kDa surface antigen
HRD70_13470	ENOG4108JA2	transcriptioN-repair coupling factor
HRD70_13475	ENOG4105D60	lipoprotein releasing system transmembrane protein
HRD70_13485	ENOG4105D60	lipoprotein releasing system transmembrane protein
HRD70_13490	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HRD70_13505	ENOG4105EZE	Cupin 4 family protein
HRD70_13515	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HRD70_13525	ENOG4107QTF	adenylosuccinate lyase
HRD70_13530	ENOG41075W9	High frequency lysogenization protein HflD homolog
HRD70_13535	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HRD70_13545	ENOG4108R99	pseudouridine synthase
HRD70_13550	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HRD70_13555	ENOG4108I1J	Integrase
HRD70_13580	ENOG4106NDP	Transcriptional regulator
HRD70_13590	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRD70_13600	ENOG4105ECQ	AraC Family Transcriptional Regulator
HRD70_13605	ENOG4108IQK	o-acetylhomoserine
HRD70_13610	ENOG4105ECR	NmrA family
HRD70_13615	ENOG4105KVH	Transcriptional regulator
HRD70_13670	ENOG4105XXV	Acid-resistance protein
HRD70_13685	ENOG4105BZ1	(ABC) transporter
HRD70_13695	ENOG4105D5Q	Arginine ornithine antiporter
HRD70_13710	ENOG4105N4N	Protein of unknown function (DUF2766)
HRD70_13715	ENOG4105TIK	
HRD70_13725	ENOG41064PC	
HRD70_13740	ENOG4105C85	amino acid
HRD70_13745	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
HRD70_13760	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HRD70_13765	ENOG4105CJN	penicillin-binding protein
HRD70_13770	ENOG4105DHI	Methyltransferase
HRD70_13780	ENOG4105BZU	Histidine kinase
HRD70_13790	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HRD70_13795	ENOG4108NK4	UPF0266 membrane protein
HRD70_13800	ENOG4105F3R	pts system mannose fructose sorbose family iid
HRD70_13805	ENOG4105ETZ	PTS System
HRD70_13810	ENOG4105DAS	pts system
HRD70_13815	ENOG4105EE5	Membrane protein terC
HRD70_13825	ENOG4105EJQ	L-serine dehydratase
HRD70_13830	ENOG4105P8F	nudix hydrolase
HRD70_13840	ENOG4105X5C	UPF0181 protein
HRD70_13845	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HRD70_13850	ENOG4105C1J	atp-dependent rna helicase
HRD70_13855	ENOG4105X2V	dna damage-inducible protein
HRD70_13860	ENOG4105N5Z	UPF0267 protein
HRD70_13870	ENOG4105CUG	Oligopeptidase b
HRD70_13875	ENOG4105UMD	exodeoxyribonuclease X
HRD70_13885	ENOG4105MPK	DNA polymerase III subunit theta
HRD70_13890	ENOG41090A1	ferritin
HRD70_13895	ENOG4105FXM	Copper resistance protein
HRD70_13900	ENOG4108PNC	copper resistance
HRD70_13905	ENOG4105NKT	exported protein
HRD70_14045	ENOG4105DH7	May be involved in recombination (By similarity)
HRD70_14075	ENOG4105RWQ	Protein of unknown function (DUF1364)
HRD70_14105	ENOG4105KUS	lysozyme
HRD70_14260	ENOG41066YJ	Beta-lactamase
HRD70_14270	ENOG4105FE9	pseudouridine synthase
HRD70_14275	ENOG4105D6U	Sodium Glutamate Symporter
HRD70_14295	ENOG4105D64	Mechanosensitive ion channel
HRD70_14300	ENOG4108SHQ	Glutathione S-transferase
HRD70_14320	ENOG4105WT8	Protein of unknown function (DUF1480)
HRD70_14360	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD70_14370	ENOG4105DY2	Paraquat-inducible protein b
HRD70_14375	ENOG4105H2K	paraquat-inducible protein a
HRD70_14380	ENOG4108ZGC	gaf domain protein
HRD70_14390	ENOG4105CN1	protease
HRD70_14395	ENOG4105D0M	Protease HtpX homolog
HRD70_14405	ENOG4106JJN	Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae
HRD70_14415	ENOG4106PH7	chaperone
HRD70_14420	ENOG4108AF8	Chaperone
HRD70_14425	ENOG4105CW0	outer membrane usher protein
HRD70_14435	ENOG4108WQH	regulatoR
HRD70_14440	ENOG4105BZU	Histidine kinase
HRD70_14445	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD70_14450	ENOG4105CAZ	oligogalacturonide lyase
HRD70_14460	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HRD70_14465	ENOG4108ETY	sodium dicarboxylate symporter
HRD70_14470	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HRD70_14475	ENOG4108PU9	oligogalacturonate-specific porin
HRD70_14480	ENOG4105WEM	extracellular solute-binding protein
HRD70_14490	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HRD70_14495	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HRD70_14500	ENOG41061NF	Pectate lyase
HRD70_14505	ENOG4105CHR	reductase
HRD70_14510	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HRD70_14515	ENOG4105M5J	Cupin 2, conserved barrel domain protein
HRD70_14520	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HRD70_14525	ENOG4107PN8	YfeABCD locus regulator
HRD70_14535	ENOG4105CC5	ABC transporter
HRD70_14540	ENOG4105CC5	ABC transporter
HRD70_14545	ENOG4105DIK	(ABC) transporter
HRD70_14550	ENOG4105DSE	periplasmic solute binding protein
HRD70_14555	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HRD70_14560	ENOG41082NP	Multiple antibiotic resistance
HRD70_14585	ENOG41087WU	
HRD70_14605	ENOG4105C22	threonyL-tRNA synthetase
HRD70_14610	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HRD70_14640	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HRD70_14645	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HRD70_14655	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HRD70_14660	ENOG4108V06	Glutathione peroxidase
HRD70_14665	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
HRD70_14670	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRD70_14675	ENOG4105CKK	Glycosyl transferase, family 2
HRD70_14680	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD70_14685	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD70_14690	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD70_14695	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HRD70_14700	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HRD70_14705	ENOG4108QBX	(LipO)protein
HRD70_14710	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
HRD70_14720	ENOG4107R4I	Periplasmic binding protein
HRD70_14725	ENOG4106QJH	hemin transport protein
HRD70_14730	ENOG4107ENK	receptor
HRD70_14735	ENOG4107F3C	Hemin uptake protein
HRD70_14740	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD70_14745	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HRD70_14750	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HRD70_14760	ENOG4105IPI	Membrane
HRD70_14770	ENOG4105CQB	FAD linked oxidase domain protein
HRD70_14775	ENOG4105KA0	thioesterase Superfamily protein
HRD70_14780	ENOG4108Z4V	iron-sulfur cluster assembly
HRD70_14785	ENOG4105DIW	FeS assembly protein SUFB
HRD70_14790	ENOG4105C3K	feS assembly ATPase SufC
HRD70_14795	ENOG4105JRK	feS assembly protein SufD
HRD70_14805	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HRD70_14810	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HRD70_14820	ENOG4105CA9	Pyruvate kinase
HRD70_14840	ENOG4107QI1	Mate efflux family protein
HRD70_14845	ENOG4108R6K	riboflavin synthase, subunit alpha
HRD70_14850	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HRD70_14855	ENOG4105CZQ	inner membrane transport protein YdhC
HRD70_14860	ENOG4105F52	Transcriptional regulator
HRD70_14865	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_14875	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HRD70_14880	ENOG4105K4H	Nlp p60 protein
HRD70_14885	ENOG4105M2J	Glutaredoxin
HRD70_14890	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HRD70_14895	ENOG4108UYE	Lactoylglutathione lyase
HRD70_14905	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HRD70_14910	ENOG4108WUH	Transcriptional regulator, TetR family
HRD70_14915	ENOG4105DIJ	Phosphoethanolamine transferase
HRD70_14920	ENOG4105XZD	Fe-S protein
HRD70_14925	ENOG4107RGM	aldo keto reductase
HRD70_14930	ENOG4105DSW	Fusaric acid resistance protein
HRD70_14935	ENOG4105Y49	secretion protein, HlyD family
HRD70_14945	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
HRD70_14950	ENOG4108XTF	Outer Membrane Lipoprotein
HRD70_14955	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HRD70_14960	ENOG410642K	Lysozyme inhibitor
HRD70_14970	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HRD70_14980	ENOG4108K3A	Glutathione S-transferase
HRD70_14985	ENOG4108ZR5	Conserved Protein
HRD70_14990	ENOG41069YE	inner membrane protein yohC
HRD70_15000	ENOG4105DUX	Transporter
HRD70_15005	ENOG4105DUM	transcriptional regulator, lysR family
HRD70_15010	ENOG4105Q4T	oxidoreductase
HRD70_15015	ENOG4108JQ2	peptide transport system atp-binding protein
HRD70_15020	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HRD70_15025	ENOG4108EU3	peptide transport system, permease
HRD70_15030	ENOG4108I5W	peptide transport system, permease protein
HRD70_15035	ENOG4108HIY	periplasmic
HRD70_15050	ENOG4105E51	psp operon transcriptional activator
HRD70_15055	ENOG41087YS	Phage shock protein A
HRD70_15060	ENOG4105YYT	phage shock protein B
HRD70_15065	ENOG4105FM1	phage shock protein C
HRD70_15075	ENOG4105CM6	amino acid regulated cytosolic protein
HRD70_15080	ENOG4106K28	UPF0283 membrane protein
HRD70_15100	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HRD70_15105	ENOG4107S8C	mandelate racemase muconate lactonizing
HRD70_15110	ENOG4105KXI	murein peptide amidase A
HRD70_15115	ENOG4107QSI	ABC, transporter
HRD70_15130	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HRD70_15140	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
HRD70_15150	ENOG4105KT7	mgtC SapB transporter
HRD70_15155	ENOG4105IKK	cytoplasmic protein
HRD70_15160	ENOG41090X5	Heat shock protein hslJ
HRD70_15165	ENOG4105C5I	Dehydrogenase
HRD70_15170	ENOG4107H52	Dicarboxylate transport
HRD70_15175	ENOG410689M	(LipO)protein
HRD70_15180	ENOG4105WXT	Conserved Protein
HRD70_15185	ENOG4105IE8	Alpha-ketoglutarate permease
HRD70_15190	ENOG4105CMG	Carbohydrate kinase
HRD70_15195	ENOG4105DEI	Mannitol dehydrogenase
HRD70_15205	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HRD70_15210	ENOG4105CQ7	ATP-dependent helicase
HRD70_15225	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
HRD70_15235	ENOG4105CTD	carboxy-peptidase
HRD70_15240	ENOG4105JJR	Histidine kinase
HRD70_15245	ENOG4107EXC	regulatoR
HRD70_15255	ENOG4105D5Q	Arginine ornithine antiporter
HRD70_15260	ENOG4105C5D	exported protein
HRD70_15265	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HRD70_15270	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HRD70_15275	ENOG4105Q9Y	Universal stress protein
HRD70_15280	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HRD70_15285	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HRD70_15300	ENOG4108S5C	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity)
HRD70_15330	ENOG4105PAD	Hydrolase
HRD70_15340	ENOG4105M71	acetolactate synthase 1 regulatory subunit
HRD70_15345	ENOG4105C7K	acetolactate synthase
HRD70_15360	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HRD70_15385	ENOG4105CBN	LysR family transcriptional regulator
HRD70_15390	ENOG4105FYV	Amp nucleosidase
HRD70_15395	ENOG4108KSA	LysR family transcriptional regulator
HRD70_15405	ENOG4106V2I	dimethylaminohydrolase
HRD70_15410	ENOG4105E89	ABC transporter
HRD70_15415	ENOG4105DSP	amino acid AbC transporter
HRD70_15425	ENOG4108RYR	transcriptional regulator AsnC family
HRD70_15435	ENOG4105CYM	Glutathione S-transferase
HRD70_15475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD70_15480	ENOG4105EMU	Dehydrogenase
HRD70_15485	ENOG4105KK4	UPF0060 membrane protein
HRD70_15490	ENOG4105M5Q	UPF0482 protein
HRD70_15495	ENOG4105KBG	Protein of unknown function (DUF1161)
HRD70_15510	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HRD70_15515	ENOG4105DAG	ROK family
HRD70_15520	ENOG4106NZI	LysR family Transcriptional regulator
HRD70_15525	ENOG4105D94	Major Facilitator Superfamily
HRD70_15535	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
HRD70_15545	ENOG4105C9Q	fumarate hydratase class II
HRD70_15550	ENOG4105EIP	mannose-6-phosphate isomerase
HRD70_15555	ENOG4106J39	exported protein
HRD70_15565	ENOG4107P2S	Transcriptional regulator
HRD70_15570	ENOG4105CI1	PTS System
HRD70_15575	ENOG4105C87	Aminotransferase class I and II
HRD70_15580	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HRD70_15585	ENOG4105DHU	Bile acid
HRD70_15590	ENOG4105D9R	oxidoreductase
HRD70_15605	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HRD70_15610	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HRD70_15615	ENOG4108JJA	ABC, transporter
HRD70_15630	ENOG4105CKU	formyltetrahydrofolate synthetase
HRD70_15635	ENOG4105M9B	inner membrane protein ydgK
HRD70_15650	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HRD70_15655	ENOG4105UEI	Transcriptional Regulator AraC Family
HRD70_15660	ENOG4105D6A	Electron transport complex
HRD70_15665	ENOG4108UQQ	Electron transport complex
HRD70_15675	ENOG4105CSM	endonuclease III
HRD70_15695	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HRD70_15700	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HRD70_15705	ENOG4105D22	carbon starvation protein
HRD70_15710	ENOG4105VCD	cytoplasmic protein
HRD70_15715	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HRD70_15720	ENOG4105N2W	Transcriptional regulator
HRD70_15730	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HRD70_15740	ENOG4108ZJT	translation initiation factor, Sui1
HRD70_15745	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HRD70_15750	ENOG4105RC8	Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction
HRD70_15765	ENOG4105KVH	Transcriptional regulator
HRD70_15770	ENOG4105CHR	reductase
HRD70_15775	ENOG4105CFV	Tetratricopeptide repeat protein
HRD70_15780	ENOG4105Q4A	inner membrane protein yciS
HRD70_15785	ENOG4105EYK	Phosphatidylglycerophosphatase B
HRD70_15795	ENOG4107QM5	aconitate hydratase
HRD70_15810	ENOG4107R11	Transcriptional regulator
HRD70_15815	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRD70_15820	ENOG4105RKX	Protein of unknown function (DUF2498)
HRD70_15825	ENOG4105ERU	peptidase
HRD70_15830	ENOG4105UBK	short-chain dehydrogenase reductase
HRD70_15835	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HRD70_15845	ENOG4105FE9	pseudouridine synthase
HRD70_15850	ENOG4108WQH	regulatoR
HRD70_15865	ENOG4105TNG	K13735 adhesin invasin
HRD70_15875	ENOG4108Q9V	regulatoR
HRD70_15885	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HRD70_15890	ENOG4105DB7	PHP domain protein
HRD70_15900	ENOG4105DDQ	anthranilate synthase
HRD70_15910	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HRD70_15915	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HRD70_15920	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HRD70_15930	ENOG4105EIF	outer membrane protein W
HRD70_15935	ENOG4105PI0	Ferredoxin
HRD70_15940	ENOG4108S3I	UPF0259 membrane protein
HRD70_15950	ENOG4107835	probably involved in intracellular septation (By similarity)
HRD70_15955	ENOG4105NAU	thioesterase Superfamily protein
HRD70_15960	ENOG410822N	TonB family
HRD70_15965	ENOG4105K9H	YciI-like protein
HRD70_15980	ENOG4105CMB	EAL domain-containing protein
HRD70_15990	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HRD70_15995	ENOG4108W5H	UPF0263 protein
HRD70_16000	ENOG4108JQ7	(ABC) transporter
HRD70_16005	ENOG4105C3U	ABC transporter
HRD70_16010	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD70_16015	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD70_16020	ENOG4107QSI	ABC, transporter
HRD70_16025	ENOG4107QSI	ABC, transporter
HRD70_16030	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HRD70_16035	ENOG4105C0A	alcohol dehydrogenase
HRD70_16050	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HRD70_16055	ENOG4105I93	response regulator
HRD70_16060	ENOG4105D78	K07001 NTE family protein
HRD70_16070	ENOG4105K5B	UPF0225 protein
HRD70_16075	ENOG4105CIY	formyltetrahydrofolate deformylase
HRD70_16090	ENOG4105SKE	transcriptional Regulator LysR family
HRD70_16095	ENOG4105CGK	Exodeoxyribonuclease III
HRD70_16100	ENOG4105M6F	mutator MutT protein
HRD70_16105	ENOG4105MTM	Protein of unknown function (DUF1496)
HRD70_16110	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRD70_16120	ENOG41069NU	Nitroreductase
HRD70_16125	ENOG4105D07	Signal peptide peptidase, SppA
HRD70_16130	ENOG4105HDK	L-asparaginase
HRD70_16135	ENOG4108RWI	nicotinamidase
HRD70_16140	ENOG4105VUT	cytoplasmic protein
HRD70_16145	ENOG4105E0X	reductase
HRD70_16155	ENOG4105DSB	aldose 1-epimerase
HRD70_16160	ENOG4105GNX	MltA-interacting MipA family protein
HRD70_16165	ENOG4105CYN	Serine protein kinase
HRD70_16170	ENOG4106AKX	UPF0229 protein
HRD70_16185	ENOG4105HEI	LysR family (Transcriptional regulator
HRD70_16190	ENOG4105EUB	pirin domain protein
HRD70_16195	ENOG4105BZU	Histidine kinase
HRD70_16200	ENOG4105CNH	Multidrug resistance protein MdtL
HRD70_16205	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HRD70_16210	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HRD70_16215	ENOG4105ED1	spovr family
HRD70_16220	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
HRD70_16225	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HRD70_16230	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HRD70_16235	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD70_16400	ENOG4108TFU	terminase (Small subunit)
HRD70_16415	ENOG4105KUS	lysozyme
HRD70_16470	ENOG4105CDU	Replicative dna helicase
HRD70_16570	ENOG41076J9	exonuclease VIII
HRD70_16620	ENOG4107R08	Integrase
HRD70_16625	ENOG4108ZZ3	UPF0260 protein
HRD70_16630	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HRD70_16635	ENOG4105CVE	Lytic murein transglycosylase
HRD70_16640	ENOG4105VNG	YcgL domain-containing protein
HRD70_16650	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HRD70_16655	ENOG4107QMS	site-determining protein
HRD70_16660	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HRD70_16665	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HRD70_16670	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD70_16675	ENOG4105Y4Z	Outer Membrane Lipoprotein
HRD70_16680	ENOG41072GX	Peptidase M22 Glycoprotease
HRD70_16685	ENOG4105DVT	helicase
HRD70_16690	ENOG4105M4H	endoribonuclease L-psp
HRD70_16700	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
HRD70_16705	ENOG4108UHU	Aldolase
HRD70_16710	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HRD70_16715	ENOG4106KNT	transcriptional regulator
HRD70_16720	ENOG4105CA9	Pyruvate kinase
HRD70_16725	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HRD70_16730	ENOG4105DR5	peptidase
HRD70_16735	ENOG4105NXV	High-affinity zinc uptake system protein
HRD70_16740	ENOG4105FDK	ABC transporter
HRD70_16745	ENOG4105FAV	ABC, transporter
HRD70_16750	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HRD70_16755	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HRD70_16760	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HRD70_16765	ENOG4105CDY	transcriptional regulatory protein
HRD70_16770	ENOG4108TIT	dATP pyrophosphohydrolase
HRD70_16775	ENOG4105C9M	aspartyl-trna synthetase
HRD70_16780	ENOG4105D3W	isochorismatase
HRD70_16785	ENOG41081XQ	Conserved Protein
HRD70_16790	ENOG4105WJG	Glutathione
HRD70_16795	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HRD70_16800	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HRD70_16805	ENOG4106N3A	copper homeostasis protein cutc
HRD70_16810	ENOG4106ZCM	YecM protein
HRD70_16815	ENOG4105C75	arginyL-tRNA synthetase
HRD70_16825	ENOG4105CJR	Integral membrane protein (MviN
HRD70_16830	ENOG4105EP9	oxidoreductase
HRD70_16840	ENOG4105D9U	N-acetyltransferase
HRD70_16845	ENOG4105EV4	Multidrug resistance protein mdtH
HRD70_16850	ENOG4105F3T	(LipO)protein
HRD70_16855	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HRD70_16860	ENOG4107SSZ	Phosphatase
HRD70_16865	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HRD70_16885	ENOG4105BZU	Histidine kinase
HRD70_16890	ENOG4105CHH	sulfate transporter
HRD70_16895	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HRD70_16900	ENOG41063JG	Transcriptional regulator
HRD70_16905	ENOG4108YY7	Invasion gene expression up-regulator SirB
HRD70_16910	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HRD70_16915	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HRD70_16920	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HRD70_16925	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HRD70_16935	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HRD70_16940	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
HRD70_16945	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HRD70_16955	ENOG4105C3G	gtp-binding protein
HRD70_16960	ENOG4105UNS	Pfam:DUF419
HRD70_16965	ENOG4105E98	transcriptional regulator DeoR family
HRD70_16970	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HRD70_16975	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HRD70_16985	ENOG4105F3R	pts system mannose fructose sorbose family iid
HRD70_16990	ENOG4108YTN	IIa component
HRD70_16995	ENOG4105E70	isomerase
HRD70_17000	ENOG4105D2N	Aldolase
HRD70_17010	ENOG4108K5P	(LipO)protein
HRD70_17020	ENOG4108MEK	Metal-binding protein YodA
HRD70_17025	ENOG4108HWV	)-transporter
HRD70_17030	ENOG4105C2J	ABC transporter
HRD70_17040	ENOG41090B9	response to stress
HRD70_17045	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HRD70_17050	ENOG4105CZE	histidine utilization repressor
HRD70_17055	ENOG4105CI2	imidazolone-5-propionate hydrolase
HRD70_17070	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
HRD70_17075	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HRD70_17085	ENOG4105F4X	arginine
HRD70_17100	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HRD70_17105	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HRD70_17115	ENOG4105BZU	Histidine kinase
HRD70_17120	ENOG4107R11	Transcriptional regulator
HRD70_17130	ENOG4105EWV	Sodium calcium exchanger membrane region
HRD70_17135	ENOG4105D5M	phosphate starvation-inducible protein
HRD70_17150	ENOG4105CND	Glycosyl transferase, family 2
HRD70_17155	ENOG4107BJW	polysaccharide deacetylase
HRD70_17160	ENOG4108TUY	outer membrane protein PgaA
HRD70_17165	ENOG4107RAQ	aminopeptidase
HRD70_17170	ENOG4108819	ferric iron reductase
HRD70_17175	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HRD70_17180	ENOG4105EXG	Transcriptional regulator
HRD70_17200	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HRD70_17210	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HRD70_17225	ENOG4107SJW	iron permease, FTR1
HRD70_17245	ENOG4105CSV	Glutaminase
HRD70_17250	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HRD70_17255	ENOG4105FB2	class II Aldolase
HRD70_17260	ENOG4105G63	Type III effector Hrp-dependent
HRD70_17265	ENOG4105MVE	transcriptional regulator
HRD70_17270	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HRD70_17275	ENOG4108MRH	transcriptional regulatory protein
HRD70_17285	ENOG4105C85	amino acid
HRD70_17295	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HRD70_17305	ENOG4106UW1	Major Facilitator superfamily
HRD70_17310	ENOG4108HCJ	Hydrolase
HRD70_17325	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD70_17395	ENOG4108IRC	dna polymerase iii
HRD70_17400	ENOG4105DFE	Dna adenine methylase
HRD70_17410	ENOG4105VZ1	Replication Protein
HRD70_17425	ENOG4105ED4	portal protein
HRD70_17555	ENOG4105ZTC	transcriptional activator, Ogr delta
HRD70_17575	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HRD70_17580	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HRD70_17585	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD70_17590	ENOG4105XVG	cytoplasmic protein
HRD70_17595	ENOG4105RA2	Membrane
HRD70_17605	ENOG4105E5K	Alpha-amylase
HRD70_17615	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRD70_17620	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
HRD70_17625	ENOG4105CKK	Glycosyl transferase, family 2
HRD70_17655	ENOG4105C85	amino acid
HRD70_17665	ENOG4108V1U	phospholipid-binding protein
HRD70_17670	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
HRD70_17680	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HRD70_17695	ENOG4105EKT	)-iron permease
HRD70_17700	ENOG4105CK7	Sodium proline symporter
HRD70_17705	ENOG4105C26	Dehydrogenase
HRD70_17720	ENOG4105CDA	abc transporter atp-binding protein
HRD70_17725	ENOG4105E5Q	amino acid AbC transporter
HRD70_17730	ENOG4105EAB	amino acid AbC transporter
HRD70_17735	ENOG4105K6H	D-cysteine desulfhydrase
HRD70_17740	ENOG4108M9K	flagella biosynthesis protein FliZ
HRD70_17745	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD70_17750	ENOG4105I03	Flagellin
HRD70_17755	ENOG4105DTS	flagellar hook-associated
HRD70_17760	ENOG4105MQ3	flagellar protein FliS
HRD70_17765	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
HRD70_17770	ENOG4108NKV	transcriptional regulator
HRD70_17775	ENOG4105DHT	Metal Dependent Phosphohydrolase
HRD70_17780	ENOG4105WS7	Cation transport regulator
HRD70_17795	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HRD70_17800	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HRD70_17805	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD70_17810	ENOG41090PJ	Flagellar assembly protein
HRD70_17815	ENOG4108JIR	Flagellum-specific ATP synthase
HRD70_17825	ENOG4105WF4	Flagellar hook-length control protein
HRD70_17830	ENOG4107ZI8	flagellar basal body-associated protein flil
HRD70_17835	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD70_17840	ENOG4105DD5	Flagellar motor switch protein
HRD70_17850	ENOG4105CN7	Flagellar biosynthetic protein FliP
HRD70_17855	ENOG4105VS8	Flagellar biosynthetic protein fliq
HRD70_17860	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HRD70_17865	ENOG4105DTJ	flagellar hook-associated protein
HRD70_17870	ENOG4105E1Q	flagellar hook-associated protein
HRD70_17875	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HRD70_17890	ENOG4105CGA	flagellar basal-body rod protein FlgG
HRD70_17895	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HRD70_17900	ENOG4105BZE	flagellar hook protein, FlgE
HRD70_17905	ENOG4105W00	Flagellar hook capping protein
HRD70_17910	ENOG4108ZC9	flagellar basal-body rod protein flgc
HRD70_17915	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HRD70_17920	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HRD70_17925	ENOG4105M9M	anti-sigma28 factor FlgM
HRD70_17930	ENOG4105QVD	Flagella synthesis protein FlgN
HRD70_17935	ENOG4105TNG	K13735 adhesin invasin
HRD70_17945	ENOG4105W13	flagellar protein
HRD70_17950	ENOG4105D7B	Flagellar biosynthesis protein flha
HRD70_17955	ENOG4105D00	flagellar biosynthetic protein flhB
HRD70_17965	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HRD70_17970	ENOG4108VYJ	response regulator receiver protein
HRD70_17980	ENOG4105BZU	Histidine kinase
HRD70_17985	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_17990	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_17995	ENOG4105D7W	serine acetyltransferase
HRD70_18000	ENOG4105C6T	cysteine synthase
HRD70_18020	ENOG4105ESN	nucleotide-binding protein
HRD70_18025	ENOG4105C9B	Cysteine desulfurase
HRD70_18030	ENOG4108V3W	Chemotaxis protein, CheW
HRD70_18035	ENOG4105CBS	Chea signal transduction histidine kinase
HRD70_18040	ENOG4105ER2	Ompa motb domain protein
HRD70_18045	ENOG4107RD7	Flagellar Motor Protein, MotA
HRD70_18050	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HRD70_18055	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HRD70_18060	ENOG4108VA4	Universal stress protein
HRD70_18065	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HRD70_18070	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HRD70_18075	ENOG4105KT7	mgtC SapB transporter
HRD70_18080	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_18085	ENOG4105VZF	DsrB protein
HRD70_18095	ENOG4105ETE	Transcriptional regulator (LacI family
HRD70_18100	ENOG4105CNT	hydrolase family 2
HRD70_18110	ENOG4105GSJ	Inner membrane protein ylaC
HRD70_18125	ENOG41061EV	selenium-binding protein YdfZ
HRD70_18130	ENOG4105D6F	Phosphatase
HRD70_18135	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HRD70_18140	ENOG4108S1B	Periplasmic chaperone protein
HRD70_18145	ENOG4108D1K	outer membrane usher protein
HRD70_18165	ENOG4105CMG	Carbohydrate kinase
HRD70_18170	ENOG4108M3J	Dehydrogenase
HRD70_18175	ENOG4105D7K	pfkb domain protein
HRD70_18180	ENOG4105CNN	ABC, transporter
HRD70_18210	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HRD70_18220	ENOG4105D3G	Pseudouridine synthase
HRD70_18235	ENOG4108TSE	Transferase
HRD70_18240	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HRD70_18250	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HRD70_18255	ENOG4107QPK	)-transporter
HRD70_18260	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HRD70_18265	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HRD70_18270	ENOG4105CHY	citrate lyase, alpha
HRD70_18275	ENOG4105CI0	Citrate lyase
HRD70_18280	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
HRD70_18285	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
HRD70_18290	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HRD70_18295	ENOG4106YYS	transcriptional regulatory protein
HRD70_18300	ENOG4108KX4	response regulator
HRD70_18305	ENOG4105BZU	Histidine kinase
HRD70_18315	ENOG4105C4Y	ABC transporter
HRD70_18325	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD70_18335	ENOG4108Q9V	regulatoR
HRD70_18340	ENOG4105BZU	Histidine kinase
HRD70_18350	ENOG4105GQR	Chaperone
HRD70_18355	ENOG4105CW0	outer membrane usher protein
HRD70_18365	ENOG4108MQF	Chaperone
HRD70_18375	ENOG4105F5R	ABC transporter
HRD70_18385	ENOG4105CNN	ABC, transporter
HRD70_18395	ENOG4105C2J	ABC transporter
HRD70_18405	ENOG4105EMU	Dehydrogenase
HRD70_18410	ENOG4105CPC	Aldo Keto reductase
HRD70_18420	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD70_18430	ENOG4105HEI	LysR family (Transcriptional regulator
HRD70_18435	ENOG4107S1E	Beta-lactamase
HRD70_18445	ENOG4105E98	transcriptional regulator DeoR family
HRD70_18450	ENOG410667J	hydrolase
HRD70_18455	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HRD70_18475	ENOG4105UQX	Mate efflux family protein
HRD70_18480	ENOG4105CDH	Citrulline--aspartate ligase
HRD70_18485	ENOG4105EAA	nucleoside
HRD70_18490	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HRD70_18500	ENOG4105CN8	Transcriptional regulator
HRD70_18505	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HRD70_18510	ENOG4108TGR	phosphatase
HRD70_18520	ENOG4108YZT	Adenosylcobinamide kinase
HRD70_18525	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HRD70_18535	ENOG4108V4M	Cobalt abc transporter
HRD70_18545	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
HRD70_18550	ENOG4105DVK	Precorrin-2 c20-methyltransferase
HRD70_18555	ENOG4107PPM	cobalt chelatase
HRD70_18560	ENOG4105QUC	reductase
HRD70_18565	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HRD70_18570	ENOG4108P62	biosynthesis protein (CbiG)
HRD70_18575	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HRD70_18580	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
HRD70_18585	ENOG4108DR9	Cobalt-precorrin-6Y C(5)-methyltransferase
HRD70_18590	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
HRD70_18595	ENOG41081F0	Precorrin-8x methylmutase
HRD70_18600	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HRD70_18605	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HRD70_18610	ENOG4107XVH	Transcriptional regulator
HRD70_18615	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HRD70_18620	ENOG4105KNY	Microcompartments protein
HRD70_18625	ENOG4105EHR	propanediol utilization protein pduB
HRD70_18630	ENOG4105DMB	glycerol dehydratase
HRD70_18635	ENOG4105YCI	dehydratase medium subunit
HRD70_18640	ENOG4108ZFT	Dehydratase small subunit
HRD70_18645	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
HRD70_18655	ENOG4105KNY	Microcompartments protein
HRD70_18665	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
HRD70_18685	ENOG4108EKI	Dehydrogenase
HRD70_18695	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HRD70_18705	ENOG4105M3W	utilization protein
HRD70_18710	ENOG4105KTW	ethanolamine utilization protein
HRD70_18715	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HRD70_18720	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRD70_18725	ENOG4107QZB	decarboxylase
HRD70_18730	ENOG4105JZC	GHMP kinase
HRD70_18735	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HRD70_18745	ENOG4105CNN	ABC, transporter
HRD70_18750	ENOG4108HWW	ABC transporter
HRD70_18760	ENOG4105DR8	Membrane
HRD70_18765	ENOG4105E4E	Thioester reductase domain-containing protein
HRD70_18770	ENOG4105CJB	Exodeoxyribonuclease I
HRD70_18775	ENOG4105CUB	amino acid
HRD70_18780	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
HRD70_18785	ENOG4105C2J	ABC transporter
HRD70_18790	ENOG4105CNN	ABC, transporter
HRD70_18795	ENOG4107SRH	Nad-dependent epimerase dehydratase
HRD70_18805	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HRD70_18815	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HRD70_18820	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HRD70_18830	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HRD70_18835	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HRD70_18840	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HRD70_18845	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HRD70_18850	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HRD70_18855	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HRD70_18860	ENOG4105EE5	Membrane protein terC
HRD70_18865	ENOG4105CEE	C4-dicarboxylate transporter
HRD70_18870	ENOG4108GAE	asmA family
HRD70_18875	ENOG4105DHP	deoxycytidine triphosphate deaminase
HRD70_18880	ENOG4105DBI	uridine monophosphokinase
HRD70_18885	ENOG4105D1F	ATP-binding protein
HRD70_18890	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HRD70_18910	ENOG4105E5W	Transporter
HRD70_18915	ENOG4105VAW	lrga family
HRD70_18920	ENOG41067MG	lrgb family
HRD70_18935	ENOG4107R1I	NAD-dependent malic enzyme
HRD70_18940	ENOG4107GZ4	SanA protein
HRD70_18950	ENOG410816D	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HRD70_18955	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HRD70_18960	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HRD70_18965	ENOG4107TDF	Formate hydrogenlyase subunit 4
HRD70_18970	ENOG4105D65	subunit l
HRD70_18975	ENOG4107WQX	hydrogenase 4 membrane subunit
HRD70_18980	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HRD70_18985	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD70_18995	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HRD70_19000	ENOG4105I6X	formate hydrogenlyase maturation
HRD70_19005	ENOG4108MG9	hydrogenase 3 maturation protease
HRD70_19010	ENOG4108RC0	Electron transport protein
HRD70_19015	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HRD70_19020	ENOG4108JUA	Transcriptional regulator
HRD70_19025	ENOG4105TMB	Formate nitrite transporter
HRD70_19030	ENOG4107SDZ	Galactoside transport system permease protein mglC
HRD70_19045	ENOG41060NJ	transcriptional regulator
HRD70_19050	ENOG4105DHF	Membrane
HRD70_19055	ENOG4105EUJ	GTP cyclohydrolase i
HRD70_19060	ENOG4105CBP	Major Facilitator
HRD70_19065	ENOG4105EGI	Transcriptional regulator
HRD70_19105	ENOG4105CSH	Transporter
HRD70_19115	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HRD70_19120	ENOG4105D06	uba thif-type nad fad binding protein
HRD70_19125	ENOG4105C5H	ABC transporter
HRD70_19135	ENOG4108T1M	outer membrane protein x
HRD70_19165	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HRD70_19170	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HRD70_19175	ENOG4107R0W	ABC transporter
HRD70_19180	ENOG4105E5Q	amino acid AbC transporter
HRD70_19185	ENOG4105CDA	abc transporter atp-binding protein
HRD70_19190	ENOG4107SDU	Methyl-accepting chemotaxis
HRD70_19195	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
HRD70_19215	ENOG4108MTB	glycosyl transferase family
HRD70_19220	ENOG4105EJC	lysr family transcriptional regulator
HRD70_19230	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HRD70_19235	ENOG4105DVT	helicase
HRD70_19250	ENOG4105FDR	Membrane
HRD70_19265	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
HRD70_19270	ENOG4108IJ8	ABC transporter
HRD70_19275	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
HRD70_19280	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HRD70_19295	ENOG4105KHC	sulfurtransferase
HRD70_19300	ENOG4108W15	Protein of unknown function (DUF1456)
HRD70_19315	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
HRD70_19325	ENOG4105Y3U	Transglycosylase-associated protein
HRD70_19335	ENOG4105N1F	Hnh endonuclease
HRD70_19345	ENOG4105CXG	d-lactate dehydrogenase
HRD70_19350	ENOG41061WM	D-Alanyl-D-Alanine
HRD70_19360	ENOG4105CJW	magnesium transporter
HRD70_19370	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HRD70_19375	ENOG4105C1J	atp-dependent rna helicase
HRD70_19380	ENOG4107MVR	Transcriptional regulator
HRD70_19385	ENOG4105D0S	secretion protein (HlyD
HRD70_19390	ENOG4105CJ1	ABC, transporter
HRD70_19395	ENOG4107QWP	ABC-2 type transporter
HRD70_19400	ENOG4107QWP	ABC-2 type transporter
HRD70_19405	ENOG4105HFZ	Membrane
HRD70_19410	ENOG4108ZAF	Molybdopterin
HRD70_19415	ENOG4105M00	molybdopterin converting factor, subunit 1
HRD70_19420	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRD70_19425	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRD70_19430	ENOG4105CHW	UPF0052 protein
HRD70_19435	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HRD70_19440	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HRD70_19455	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRD70_19460	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HRD70_19465	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HRD70_19475	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HRD70_19480	ENOG4108K4B	hydrolase
HRD70_19490	ENOG4105E0C	molybdate abc transporter
HRD70_19495	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HRD70_19505	ENOG4105F4R	Transcriptional regulator mode
HRD70_19510	ENOG4105DKW	ABC transporter
HRD70_19520	ENOG4105CMR	udp-glucose 4-epimerase
HRD70_19525	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HRD70_19530	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HRD70_19535	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HRD70_19545	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HRD70_19550	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD70_19555	ENOG4105PGM	cation diffusion facilitator family transporter
HRD70_19560	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HRD70_19565	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HRD70_19605	ENOG4105UFD	tol-pal system protein YbgF
HRD70_19610	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HRD70_19615	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HRD70_19620	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HRD70_19620	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HRD70_19630	ENOG4105E02	MotA TolQ exbB proton channel
HRD70_19635	ENOG4107YD3	Thioesterase
HRD70_19640	ENOG4105KJB	cyd operon protein YbgE
HRD70_19650	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HRD70_19655	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HRD70_19660	ENOG4105CGH	5'-nucleotidase
HRD70_19665	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HRD70_19675	ENOG4105C7S	Dehydrogenase
HRD70_19680	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HRD70_19685	ENOG4105E33	succinate dehydrogenase
HRD70_19695	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HRD70_19700	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HRD70_19705	ENOG4105BZN	citrate synthase
HRD70_19710	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HRD70_19725	ENOG4105E7W	lamb ycsf family protein
HRD70_19730	ENOG4107R7A	Allophanate hydrolase subunit 2
HRD70_19735	ENOG4105P4J	Allophanate hydrolase, subunit 1
HRD70_19740	ENOG4107QNR	UPF0135 protein
HRD70_19745	ENOG4107RF4	Phosphodiesterase
HRD70_19750	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HRD70_19755	ENOG4107SEY	Conserved Protein
HRD70_19760	ENOG4105EUK	rtx toxin RtxA
HRD70_19760	ENOG4105EUK	rtx toxin RtxA
HRD70_19765	ENOG4108RC6	RTX toxin
HRD70_19775	ENOG4105XIQ	Protein of unknown function (DUF2517)
HRD70_19785	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HRD70_19790	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HRD70_19795	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HRD70_19800	ENOG4105C08	Histidine kinase
HRD70_19805	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HRD70_19820	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HRD70_19830	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_19835	ENOG4105EV9	Alpha Beta Hydrolase
HRD70_19840	ENOG4105NNH	LexA regulated protein
HRD70_19845	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD70_19850	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HRD70_19855	ENOG41090R7	Ferric uptake
HRD70_19865	ENOG4105GX6	(LipO)protein
HRD70_19870	ENOG4105J5J	Outer membrane porin
HRD70_19880	ENOG4105CI1	PTS System
HRD70_19885	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HRD70_19890	ENOG4105CE4	GlcNAc 6-P deacetylase
HRD70_19895	ENOG4105E2R	ROK family
HRD70_19900	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HRD70_19905	ENOG4105CAQ	asparagine synthetase
HRD70_19940	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HRD70_19945	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HRD70_19950	ENOG4105C9A	Phoh family
HRD70_19955	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HRD70_19960	ENOG4108JU5	Magnesium and cobalt efflux protein
HRD70_19965	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HRD70_19975	ENOG4107RP9	extracellular solute-binding protein, family 3
HRD70_19980	ENOG4105EAD	ABC transporter
HRD70_19985	ENOG4105DRP	amino acid AbC transporter
HRD70_19990	ENOG4105CDA	abc transporter atp-binding protein
HRD70_19995	ENOG4105DU0	nucleoside hydrolase
HRD70_20000	ENOG4107PAI	alpha helical protein
HRD70_20005	ENOG4105C8T	Leucyl-tRNA synthetase
HRD70_20010	ENOG4108U2H	Rare lipoprotein B
HRD70_20015	ENOG4105DJF	DNA polymerase III, delta' subunit
HRD70_20020	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HRD70_20025	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HRD70_20035	ENOG4105CJN	penicillin-binding protein
HRD70_20040	ENOG4105CNI	cell division protein FtsW
HRD70_20045	ENOG4105K6T	rare lipoprotein A
HRD70_20050	ENOG4105DZ1	carboxypeptidase
HRD70_20055	ENOG4108Z43	UPF0250 protein
HRD70_20060	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HRD70_20065	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HRD70_20070	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
HRD70_20075	ENOG4105BZU	Histidine kinase
HRD70_20095	ENOG4108N8T	regulatoR
HRD70_20120	ENOG4108JJ7	ABC transporter
HRD70_20125	ENOG4105XEA	Tetr family transcriptional regulator
HRD70_20130	ENOG4105CNT	hydrolase family 2
HRD70_20135	ENOG4105CT4	transporter
HRD70_20140	ENOG4108QNI	outer membrane porin protein
HRD70_20145	ENOG4105EZE	Cupin 4 family protein
HRD70_20280	ENOG4105SZK	Rz endopeptidase from lambdoid prophage DLP12
HRD70_20430	ENOG41076J9	exonuclease VIII
HRD70_20485	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HRD70_20490	ENOG4105WQ3	Rna-binding protein
HRD70_20495	ENOG4105C8N	cysteinyl-tRNA synthetase
HRD70_20500	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HRD70_20505	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HRD70_20510	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HRD70_20515	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HRD70_20520	ENOG4105CV6	ABC transporter, permease
HRD70_20525	ENOG4108I0Y	(ABC) transporter
HRD70_20530	ENOG4108UJV	acyl-CoA thioesterase i
HRD70_20535	ENOG4105E1F	short-chain dehydrogenase reductase
HRD70_20540	ENOG4107QR8	Thioredoxin
HRD70_20545	ENOG4107QX8	SPFH domain, Band 7 family protein
HRD70_20550	ENOG4105G5H	Membrane
HRD70_20555	ENOG4108Z6Z	Transcriptional regulator
HRD70_20560	ENOG4105C59	p-type ATPase
HRD70_20565	ENOG4105MBR	gumn family
HRD70_20570	ENOG4108Z66	YbaK ebsC protein
HRD70_20575	ENOG4105CGH	5'-nucleotidase
HRD70_20580	ENOG4105EU0	Major facilitator Superfamily
HRD70_20585	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HRD70_20590	ENOG4107RE1	Inosine-guanosine kinase
HRD70_20595	ENOG4105CMR	udp-glucose 4-epimerase
HRD70_20610	ENOG4105ESV	Glycosyl transferase, family 4
HRD70_20615	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HRD70_20620	ENOG4105CG5	Glycosyl transferase (Group 1
HRD70_20625	ENOG4108SHN	Glycosyl transferase, family 2
HRD70_20635	ENOG4105ER6	polysaccharide biosynthesis protein
HRD70_20640	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HRD70_20645	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HRD70_20650	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HRD70_20655	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HRD70_20660	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HRD70_20665	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HRD70_20685	ENOG4105CKT	filamentous hemagglutinin
HRD70_20715	ENOG4105CKT	filamentous hemagglutinin
HRD70_20720	ENOG4105D5K	Hemolysin activator protein
HRD70_20725	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HRD70_20730	ENOG4105WD1	Membrane
HRD70_20740	ENOG4106428	Protein of unknown function (DUF2496)
HRD70_20745	ENOG4105EGS	Mechanosensitive ion channel
HRD70_20750	ENOG41090EX	DsrE family
HRD70_20755	ENOG4107XI7	Tetr family transcriptional regulator
HRD70_20760	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HRD70_20765	ENOG4105BZS	acriflavin resistance protein
HRD70_20775	ENOG4108626	Racemase
HRD70_20780	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HRD70_20785	ENOG4105MUZ	Protein of unknown function DUF2620
HRD70_20790	ENOG4106M0N	transport system permease protein
HRD70_20795	ENOG4105NRA	50s ribosomal protein l31 type b
HRD70_20800	ENOG4105YK5	50S ribosomal protein L36
HRD70_20805	ENOG4105DSE	periplasmic solute binding protein
HRD70_20810	ENOG4105CC5	ABC transporter
HRD70_20815	ENOG4105DIK	(ABC) transporter
HRD70_20825	ENOG4108UKR	Biofilm formation regulator YbaJ
HRD70_20830	ENOG4105KF5	hemolysin expression-modulating protein
HRD70_20840	ENOG41080UX	Methyltransferase
HRD70_20845	ENOG4108MNP	Glycoprotein polysaccharide metabolism
HRD70_20850	ENOG4105C29	acyl-CoA thioesterase
HRD70_20855	ENOG4105BZU	Histidine kinase
HRD70_20860	ENOG4108YZA	Nitrogen regulatory protein pii
HRD70_20865	ENOG4105BZ1	(ABC) transporter
HRD70_20870	ENOG4105BZ1	(ABC) transporter
HRD70_20875	ENOG4108XM1	transcriptional regulator AsnC family
HRD70_20885	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
HRD70_20890	ENOG4108NFA	extracellular solute-binding protein
HRD70_20895	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HRD70_20900	ENOG4108TGP	Thioesterase superfamily protein
HRD70_20905	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HRD70_20910	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HRD70_20915	ENOG4105K70	DNA-binding protein
HRD70_20920	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HRD70_20925	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HRD70_20935	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HRD70_20940	ENOG4105M85	Bola protein
HRD70_20945	ENOG4105IEY	(LipO)protein
HRD70_20950	ENOG4105EYM	Major Facilitator superfamily
HRD70_20960	ENOG4108NFH	Sugar hydrolase
HRD70_20965	ENOG4105E2S	oxidase) subunit II
HRD70_20970	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HRD70_20975	ENOG4105CCU	oxidase (Subunit III)
HRD70_20980	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HRD70_20985	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HRD70_20990	ENOG4107RDB	Major Facilitator
HRD70_20995	ENOG4108VPT	UPF0234 protein
HRD70_21000	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HRD70_21005	ENOG4107S0N	DJ-1 family
HRD70_21010	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HRD70_21015	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HRD70_21020	ENOG4105CTB	Polyprenyl synthetase
HRD70_21025	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HRD70_21030	ENOG4108ZAI	phosphatidylglycerophosphatase a
HRD70_21035	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HRD70_21040	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HRD70_21045	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HRD70_21050	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HRD70_21065	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRD70_21070	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRD70_21075	ENOG4105VIE	preprotein translocase, subunit YajC
HRD70_21080	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HRD70_21225	ENOG4105KUS	lysozyme
HRD70_21260	ENOG4108R1E	Serine threonine protein phosphatase 1
HRD70_21320	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HRD70_21350	ENOG41076J9	exonuclease VIII
HRD70_21400	ENOG4108KU3	Integrase
HRD70_21410	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HRD70_21415	ENOG4105D3R	alkyl hydroperoxide reductase
HRD70_21425	ENOG4105CHR	reductase
HRD70_21430	ENOG4107R28	alpha amylase, catalytic region
HRD70_21435	ENOG4105C85	amino acid
HRD70_21440	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HRD70_21450	ENOG4105BZU	Histidine kinase
HRD70_21455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRD70_21460	ENOG4107RH8	nuclease SbcCD subunit D
HRD70_21465	ENOG4105EYH	Exonuclease
HRD70_21470	ENOG4105DKQ	ROK family
HRD70_21475	ENOG4105DH7	May be involved in recombination (By similarity)
HRD70_21480	ENOG4105NBK	UPF0345 protein
HRD70_21485	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HRD70_21495	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HRD70_21510	ENOG4105F2W	methyltransferase
HRD70_21525	ENOG4105E2V	Glycosyltransferase 36
HRD70_21535	ENOG4105F8D	glycoside hydrolase family 4
HRD70_21540	ENOG4105CI1	PTS System
HRD70_21545	ENOG4105FDP	GntR family transcriptional regulator
HRD70_21550	ENOG4105D9N	nucleoside
HRD70_21555	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HRD70_21560	ENOG4105DD7	kinase (PfkB family
HRD70_21565	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HRD70_21570	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HRD70_21575	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
HRD70_21580	ENOG4105V1F	Fermentation respiration switch protein
HRD70_21585	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HRD70_21590	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
HRD70_21600	ENOG4105CG5	Glycosyl transferase (Group 1
HRD70_21605	ENOG4107STW	synthase
HRD70_21630	ENOG4105C5E	polysaccharide biosynthesis protein
HRD70_21640	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HRD70_21650	ENOG4108QY5	Ferric enterobactin transport protein
HRD70_21655	ENOG4105CIN	aminoacyl-histidine dipeptidase
HRD70_21660	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HRD70_21675	ENOG4105WWK	YheO domain protein
HRD70_21680	ENOG4105CPF	Cell wall formation (By similarity)
HRD70_21695	ENOG4105CJ2	(LipO)protein
HRD70_21700	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HRD70_21705	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD70_21710	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD70_21715	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD70_21720	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD70_21725	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD70_21730	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
HRD70_21735	ENOG4105E7A	Glutamine amidotransferase
HRD70_21745	ENOG4107QPN	acyl-Coa dehydrogenase
HRD70_21750	ENOG4106YJS	accessory processing protein
HRD70_21760	ENOG4108D1Y	Polypeptide-transport-associated domain protein, ShlB-type
HRD70_21765	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
HRD70_21770	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HRD70_21775	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HRD70_21780	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HRD70_21785	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HRD70_21795	ENOG4105CHM	Aminotransferase
HRD70_21810	ENOG4105C5R	Aminotransferase
HRD70_21820	ENOG4105E5Q	amino acid AbC transporter
HRD70_21825	ENOG4105E5Q	amino acid AbC transporter
HRD70_21840	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HRD70_21880	ENOG4105W7K	Transcriptional regulator
HRD70_21885	ENOG4105EQ0	Major Facilitator superfamily
HRD70_21890	ENOG4108UMN	azlc family
HRD70_21895	ENOG4105ZED	uncharacterized protein ygaH
HRD70_21900	ENOG4105NTK	Transcriptional repressor Mpra
HRD70_21905	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
HRD70_21910	ENOG4105CW7	secretion protein, HlyD family
HRD70_21915	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD70_21920	ENOG4105EIB	trna rrna methyltransferase
HRD70_21925	ENOG4105K63	Thioredoxin
HRD70_21930	ENOG4106IUH	DTW domain containing protein
HRD70_21940	ENOG4105JIM	Phosphatidylserine synthase
HRD70_21945	ENOG4105T42	(LipO)protein
HRD70_21980	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HRD70_21990	ENOG4108UMI	ABC transporter, permease
HRD70_21995	ENOG4105D01	(LipO)protein
HRD70_22000	ENOG4108R8X	outer membrane lipoprotein
HRD70_22005	ENOG4108R96	Methyltransferase, YaeB family
HRD70_22010	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HRD70_22015	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HRD70_22020	ENOG4108YZN	class I peptide chain release factor
HRD70_22025	ENOG4108VWS	Yaeq family
HRD70_22035	ENOG4105M1T	rho-binding antiterminator
HRD70_22040	ENOG4105N7H	Cytochrome
HRD70_22050	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HRD70_22055	ENOG4105CXN	decarboxylase
HRD70_22060	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HRD70_22065	ENOG4105C0B	DNA polymerase III (alpha subunit)
HRD70_22070	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRD70_22080	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD70_22085	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HRD70_22090	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD70_22095	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HRD70_22105	ENOG4105DZP	Membrane-associated zinc metalloprotease
HRD70_22110	ENOG4105KNE	Phosphatidate cytidylyltransferase
HRD70_22120	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HRD70_22125	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HRD70_22130	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HRD70_22135	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HRD70_22140	ENOG4105CE9	30S ribosomal protein S2
HRD70_22145	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)