locus-tag	class	description
M479_1	COG3423	Transcriptional regulator
M479_10	COG0673	inositol 2-dehydrogenase activity
M479_1000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M479_1001	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M479_1001	COG0072	phenylalanine-tRNA ligase activity
M479_1002	COG0776	regulation of translation
M479_1005	COG0386	Belongs to the glutathione peroxidase family
M479_1006	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
M479_101	COG2009	succinate dehydrogenase
M479_1014	COG0791	NLP P60 protein
M479_1019	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M479_1019	COG0574	Belongs to the PEP-utilizing enzyme family
M479_102	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M479_1020	COG0628	permease
M479_1021	COG0277	FAD linked oxidase domain protein
M479_1021	COG0247	lactate metabolic process
M479_1022	COG2050	protein possibly involved in aromatic compounds catabolism
M479_1023	COG0316	Belongs to the HesB IscA family
M479_1024	COG0719	Fe-S assembly protein
M479_1025	COG0396	ATPase activity
M479_1026	COG0719	Fe-S assembly protein
M479_1029	COG1388	LysM domain
M479_1029	COG1376	ErfK ybiS ycfS ynhG family protein
M479_103	COG1053	succinate dehydrogenase
M479_1033	COG4238	major outer membrane lipoprotein
M479_1038	COG0307	riboflavin synthase, alpha
M479_1039	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M479_1040	COG2814	Major facilitator Superfamily
M479_1041	COG0583	DNA-binding transcription factor activity
M479_1044	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M479_1045	COG0791	NLP P60 protein
M479_1047	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M479_1049	COG0346	lactoylglutathione lyase activity
M479_105	COG0567	Dehydrogenase, E1 component
M479_1051	COG1902	pentaerythritol trinitrate reductase activity
M479_1052	COG1309	transcriptional regulator
M479_1053	COG2194	sulfuric ester hydrolase activity
M479_1054	COG3313	Fe-S protein
M479_1055	COG4989	oxidoreductase activity
M479_1056	COG3133	Outer membrane lipoprotein
M479_1058	COG3895	Periplasmic Protein
M479_106	COG0508	dehydrogenase complex catalyzes the overall conversion of
M479_1062	COG0625	glutathione transferase activity
M479_1065	COG3104	oligopeptide transport
M479_1067	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M479_1067	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M479_1068	COG4172	Belongs to the ABC transporter superfamily
M479_1070	COG4171	peptide transport system, permease
M479_1071	COG4168	peptide transport system, permease
M479_1072	COG4166	transmembrane transport
M479_1074	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M479_1075	COG1842	Phage shock protein A
M479_1077	COG1983	PspC domain protein
M479_1079	COG3106	COG3106 Predicted ATPase
M479_108	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M479_1089	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M479_109	COG1943	Transposase
M479_1090	COG4948	Mandelate Racemase Muconate Lactonizing
M479_1091	COG2866	Carboxypeptidase
M479_1092	COG4166	transmembrane transport
M479_1095	COG2755	lipolytic protein G-D-S-L family
M479_1095	COG0657	acetylesterase activity
M479_1098	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M479_1098	COG0674	pyruvate-flavodoxin oxidoreductase activity
M479_1098	COG1013	pyruvate-flavodoxin oxidoreductase activity
M479_1098	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M479_11	COG0673	inositol 2-dehydrogenase activity
M479_110	COG1271	oxidase subunit
M479_1100	COG1285	pathogenesis
M479_1101	COG3042	response to heat
M479_1102	COG3187	Heat shock protein
M479_1103	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M479_1104	COG2911	Protein conserved in bacteria
M479_1106	COG3784	Protein of unknown function (DUF1318)
M479_1107	COG0246	Mannitol dehydrogenase
M479_1108	COG2390	Transcriptional regulator
M479_111	COG1294	oxidase, subunit
M479_1110	COG1643	Atp-dependent helicase
M479_1113	COG3591	Belongs to the peptidase S1B family
M479_1115	COG3038	cytochrome b561
M479_112	COG4890	Cyd operon protein YbgT
M479_1120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M479_1121	COG2205	protein histidine kinase activity
M479_1122	COG0745	RESPONSE REGULATOR receiver
M479_1124	COG0531	amino acid
M479_1126	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
M479_1127	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
M479_1128	COG0589	response to stress
M479_1129	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M479_113	COG3790	cyd operon protein YbgE
M479_1130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M479_1133	COG1011	Hydrolase
M479_1134	COG0440	acetolactate synthase activity
M479_1135	COG0028	Belongs to the TPP enzyme family
M479_114	COG0824	Thioesterase
M479_1141	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M479_1143	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M479_1144	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M479_1145	COG1879	ABC-type sugar transport system periplasmic component
M479_1147	COG1609	Transcriptional regulator
M479_1149	COG0038	chloride channel
M479_115	COG0811	peptide transport
M479_1150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
M479_1152	COG1940	carbohydrate kinase activity
M479_1153	COG0583	DNA-binding transcription factor activity
M479_1154	COG2814	Major facilitator Superfamily
M479_1156	COG0114	fumarate hydratase activity
M479_1158	COG5339	Protein conserved in bacteria
M479_116	COG0848	biopolymer transport protein
M479_1160	COG0385	Bile acid
M479_1161	COG0673	inositol 2-dehydrogenase activity
M479_1163	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_1164	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_1166	COG1879	ABC-type sugar transport system periplasmic component
M479_117	COG3064	Membrane
M479_117	COG3064	Membrane
M479_1170	COG2274	protein secretion by the type I secretion system
M479_1171	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M479_1173	COG1132	(ABC) transporter
M479_1179	COG3708	Transcriptional regulator
M479_1179	COG2207	Transcriptional regulator
M479_1180	COG4658	electron transport chain
M479_1181	COG4659	FMN binding
M479_1183	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M479_1184	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M479_1185	COG2271	Major facilitator Superfamily
M479_1187	COG1966	Carbon starvation protein
M479_1188	COG2879	small protein
M479_1189	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M479_119	COG2885	chlorophyll binding
M479_1193	COG0023	Translation Initiation Factor
M479_1196	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
M479_1197	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
M479_1198	COG0671	phosphoesterase, PA-phosphatase related
M479_1199	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M479_12	COG1879	ABC-type sugar transport system periplasmic component
M479_120	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
M479_1200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M479_1202	COG0583	DNA-binding transcription factor activity
M479_1203	COG1943	Transposase
M479_1204	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M479_1207	COG0616	signal peptide processing
M479_1208	COG1028	Short-chain dehydrogenase reductase Sdr
M479_1210	COG1187	pseudouridine synthase activity
M479_1211	COG0009	L-threonylcarbamoyladenylate synthase
M479_1214	COG0512	Glutamine amidotransferase of anthranilate synthase
M479_1216	COG0134	indole-3-glycerol-phosphate synthase activity
M479_1216	COG0135	phosphoribosylanthranilate isomerase activity
M479_1220	COG3047	cAMP biosynthetic process
M479_1225	COG1607	acyl-coa hydrolase
M479_1226	COG3328	transposase activity
M479_1227	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
M479_1228	COG2350	Protein conserved in bacteria
M479_1235	COG4608	Belongs to the ABC transporter superfamily
M479_1236	COG0444	Belongs to the ABC transporter superfamily
M479_1237	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M479_1238	COG0601	transmembrane transport
M479_1240	COG2095	MarC family integral membrane protein
M479_1241	COG1012	belongs to the aldehyde dehydrogenase family
M479_1241	COG1454	alcohol dehydrogenase
M479_1242	COG1435	thymidine kinase activity
M479_1244	COG3328	transposase activity
M479_1246	COG0745	RESPONSE REGULATOR receiver
M479_1248	COG0788	formyltetrahydrofolate deformylase activity
M479_1251	COG3328	transposase activity
M479_1252	COG0583	DNA-binding transcription factor activity
M479_1253	COG0708	Exodeoxyribonuclease III
M479_1254	COG0494	nUDIX hydrolase
M479_1256	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M479_1257	COG0709	Synthesizes selenophosphate from selenide and ATP
M479_1258	COG0778	Nitroreductase
M479_1259	COG0616	signal peptide processing
M479_1260	COG0252	asparaginase activity
M479_1261	COG1335	isochorismatase
M479_1262	COG3139	Protein of unknown function (DUF1315)
M479_1266	COG3713	MltA-interacting MipA family protein
M479_1267	COG2766	serine protein kinase
M479_127	COG1230	cation diffusion facilitator family transporter
M479_1270	COG0583	DNA-binding transcription factor activity
M479_1272	COG2814	Major facilitator Superfamily
M479_1274	COG2719	SpoVR family
M479_128	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M479_1280	COG1104	cysteine desulfurase activity
M479_129	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M479_1298	COG1943	Transposase
M479_13	COG1129	ABC transporter
M479_132	COG2017	converts alpha-aldose to the beta-anomer
M479_1333	COG0582	viral genome integration into host DNA
M479_1335	COG0179	Fumarylacetoacetate (FAA) hydrolase
M479_1336	COG2951	lytic endotransglycosylase activity
M479_1339	COG2894	cell division
M479_1340	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
M479_1341	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
M479_1342	COG0318	PFAM AMP-dependent synthetase and ligase
M479_1343	COG3065	identical protein binding
M479_1345	COG1199	ATP-dependent helicase activity
M479_1346	COG0251	oxidation-reduction process
M479_1349	COG0800	Aldolase
M479_135	COG1085	galactose-1-phosphate uridylyltransferase
M479_1351	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M479_1352	COG1737	Transcriptional regulator
M479_1353	COG0469	pyruvate kinase activity
M479_1354	COG1560	Kdo2-lipid A biosynthetic process
M479_1355	COG0739	heme binding
M479_1356	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
M479_1358	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M479_136	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M479_1363	COG0494	nUDIX hydrolase
M479_1365	COG1801	Protein of unknown function DUF72
M479_1366	COG3788	relative of glutathione S-transferase, MAPEG superfamily
M479_1370	COG3102	Protein conserved in bacteria
M479_1374	COG0728	peptidoglycan biosynthetic process
M479_1375	COG0673	inositol 2-dehydrogenase activity
M479_1376	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M479_1379	COG3381	protein complex oligomerization
M479_1382	COG1940	carbohydrate kinase activity
M479_1383	COG0584	glycerophosphoryl diester phosphodiesterase
M479_1384	COG3842	ATPase activity
M479_1385	COG1943	Transposase
M479_1387	COG1176	ABC-type spermidine putrescine transport system, permease component I
M479_1388	COG3833	ABC-type maltose transport systems, permease component
M479_1392	COG0659	secondary active sulfate transmembrane transporter activity
M479_1394	COG2912	Transglutaminase-like superfamily
M479_1395	COG3094	Invasion gene expression up-regulator, SirB
M479_1396	COG2890	protein-(glutamine-N5) methyltransferase activity
M479_14	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_140	COG1119	ATPase activity
M479_1401	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M479_1404	COG0012	GTP binding
M479_141	COG3585	molybdate ion transport
M479_141	COG2005	Transcriptional regulator
M479_1414	COG0745	RESPONSE REGULATOR receiver
M479_1418	COG5002	protein histidine kinase activity
M479_1427	COG0500	methyltransferase
M479_143	COG0725	ABC transporter, periplasmic molybdate-binding protein
M479_1432	COG3328	transposase activity
M479_144	COG4149	molybdate abc transporter
M479_1441	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M479_1442	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M479_1443	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M479_1446	COG0402	S-adenosylhomocysteine deaminase activity
M479_1452	COG3328	transposase activity
M479_146	COG0561	phosphatase activity
M479_1461	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M479_1462	COG3850	Histidine kinase
M479_1464	COG0387	Pfam Sodium calcium exchanger
M479_1465	COG1702	phosphate starvation-inducible protein PhoH
M479_1468	COG3658	cytochrome
M479_1469	COG1215	transferase activity, transferring glycosyl groups
M479_1470	COG0726	polysaccharide deacetylase
M479_1470	COG1649	PFAM Uncharacterised BCR, COG1649
M479_1471	COG0457	Tetratricopeptide repeat
M479_1472	COG0006	proline dipeptidase activity
M479_1476	COG1136	(ABC) transporter
M479_1476	COG0577	efflux transmembrane transporter activity
M479_1478	COG0577	efflux transmembrane transporter activity
M479_1478	COG1136	(ABC) transporter
M479_1481	COG0672	)-iron permease
M479_1484	COG2066	Belongs to the glutaminase family
M479_1485	COG1349	DNA-binding transcription factor activity
M479_1487	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M479_1488	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M479_1496	COG2030	dehydratase
M479_1497	COG0427	acetyl-CoA hydrolase
M479_15	COG0673	inositol 2-dehydrogenase activity
M479_1500	COG2205	protein histidine kinase activity
M479_1500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M479_1503	COG3188	usher protein
M479_1505	COG3121	Chaperone
M479_1506	COG3328	transposase activity
M479_1509	COG0582	viral genome integration into host DNA
M479_151	COG2226	methyltransferase
M479_1510	COG1169	isochorismate synthase
M479_1511	COG2814	Major facilitator Superfamily
M479_1512	COG1132	(ABC) transporter
M479_1515	COG3433	isochorismatase activity
M479_1515	COG2226	methyltransferase
M479_1515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M479_1519	COG1021	2,3-dihydroxybenzoate-AMP ligase
M479_152	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
M479_1520	COG4771	TonB-dependent receptor
M479_1533	COG0395	ABC-type sugar transport system, permease component
M479_1534	COG1175	transmembrane transport
M479_1536	COG0673	inositol 2-dehydrogenase activity
M479_154	COG0556	nucleotide-excision repair
M479_1543	COG3328	transposase activity
M479_1544	COG3328	transposase activity
M479_155	COG4628	conserved protein (DUF2132)
M479_156	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M479_1567	COG2197	response regulator
M479_1569	COG3136	membrane protein required for alginate biosynthesis
M479_1573	COG1113	amino acid transport
M479_1576	COG2837	iron assimilation
M479_158	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M479_1581	COG0506	proline dehydrogenase activity
M479_1581	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M479_1581	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M479_1588	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M479_1590	COG1191	sigma factor activity
M479_1596	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
M479_1597	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M479_16	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M479_160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M479_1600	COG1677	Flagellar hook-basal body complex protein FliE
M479_1602	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M479_1604	COG1157	protein secretion by the type III secretion system
M479_1605	COG2882	bacterial-type flagellum organization
M479_1607	COG1580	Controls the rotational direction of flagella during chemotaxis
M479_161	COG0314	molybdopterin synthase activity
M479_1612	COG1987	bacterial-type flagellum assembly
M479_1616	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M479_1617	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_1618	COG1129	ABC transporter
M479_162	COG0670	Belongs to the BI1 family
M479_1620	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_1621	COG1028	Short-chain dehydrogenase reductase Sdr
M479_1621	COG3347	Dehydrogenase
M479_1622	COG2390	Transcriptional regulator
M479_1624	COG1256	bacterial-type flagellum assembly
M479_1628	COG4786	Flagellar basal body rod
M479_163	COG1943	Transposase
M479_1630	COG1749	Flagellar hook protein flgE
M479_1631	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M479_1632	COG1558	bacterial-type flagellum-dependent cell motility
M479_1633	COG1815	bacterial-type flagellum-dependent cell motility
M479_1635	COG2747	anti-sigma28 factor FlgM
M479_1636	COG3418	PFAM FlgN family protein
M479_1641	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M479_1642	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M479_1647	COG2372	response to copper ion
M479_1648	COG1528	Iron-storage protein
M479_1651	COG1770	oligopeptidase
M479_1654	COG3141	response to X-ray
M479_1655	COG0513	Belongs to the DEAD box helicase family
M479_1660	COG1760	l-serine dehydratase
M479_1661	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M479_1662	COG2368	4-hydroxyphenylacetate
M479_1665	COG3971	2-oxopent-4-enoate hydratase activity
M479_1667	COG3384	dioxygenase
M479_1668	COG1012	belongs to the aldehyde dehydrogenase family
M479_167	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M479_1671	COG1846	Transcriptional regulator
M479_1672	COG1253	flavin adenine dinucleotide binding
M479_1673	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M479_1673	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_1674	COG3715	PTS system
M479_1675	COG3716	PTS system mannose fructose sorbose family IID component
M479_1679	COG5002	protein histidine kinase activity
M479_1679	COG5001	Diguanylate cyclase
M479_1679	COG3447	MASE1 domain protein
M479_168	COG0583	DNA-binding transcription factor activity
M479_1681	COG2226	methyltransferase
M479_1683	COG1278	Cold shock
M479_1686	COG1113	amino acid transport
M479_1693	COG2207	Transcriptional regulator
M479_1695	COG1132	(ABC) transporter
M479_1696	COG1943	Transposase
M479_170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M479_1702	COG2223	nitrite transmembrane transporter activity
M479_1707	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M479_171	COG2211	Major facilitator Superfamily
M479_1712	COG3122	Protein conserved in bacteria
M479_1716	COG0534	Mate efflux family protein
M479_1720	COG4948	Mandelate Racemase Muconate Lactonizing
M479_1722	COG1028	Short-chain dehydrogenase reductase Sdr
M479_1723	COG3011	Protein conserved in bacteria
M479_1724	COG2271	Major facilitator Superfamily
M479_1725	COG3328	transposase activity
M479_1726	COG1470	cell adhesion involved in biofilm formation
M479_1726	COG1388	LysM domain
M479_1729	COG2925	Exonuclease
M479_1730	COG0531	amino acid
M479_1732	COG0371	Dehydrogenase
M479_1733	COG1129	ABC transporter
M479_1735	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_1737	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M479_1739	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M479_174	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M479_1741	COG0131	Imidazoleglycerol-phosphate dehydratase
M479_1741	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M479_1742	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M479_1745	COG0140	phosphoribosyl-ATP diphosphatase activity
M479_1745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M479_1747	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M479_1748	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M479_1751	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M479_1752	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M479_1753	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M479_1754	COG1120	ATPase activity
M479_1757	COG3486	L-lysine 6-monooxygenase (NADPH) activity
M479_1758	COG0076	glutamate decarboxylase activity
M479_1759	COG4114	ferric iron reductase
M479_176	COG1686	Belongs to the peptidase S11 family
M479_1760	COG1253	flavin adenine dinucleotide binding
M479_1761	COG2982	Protein involved in outer membrane biogenesis
M479_1764	COG0489	protein tyrosine kinase activity
M479_1766	COG1943	Transposase
M479_177	COG0277	FAD linked oxidase domain protein
M479_1770	COG2814	Major facilitator Superfamily
M479_1772	COG1346	cytolysis
M479_1775	COG2949	membrane
M479_1778	COG4211	Belongs to the binding-protein-dependent transport system permease family
M479_1781	COG2311	Membrane
M479_1783	COG0477	Major facilitator Superfamily
M479_1784	COG0583	DNA-binding transcription factor activity
M479_179	COG1403	HNH endonuclease
M479_1790	COG1136	(ABC) transporter
M479_1792	COG0303	'Molybdopterin
M479_1795	COG0488	(ABC) transporter
M479_18	COG3718	enzyme involved in inositol metabolism
M479_181	COG2261	transglycosylase associated protein
M479_1822	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M479_1823	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M479_1825	COG1028	Short-chain dehydrogenase reductase Sdr
M479_1826	COG1024	Enoyl-CoA hydratase
M479_1828	COG3425	synthase
M479_1829	COG1028	Short-chain dehydrogenase reductase Sdr
M479_183	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
M479_1830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M479_1831	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M479_1833	COG1028	Short-chain dehydrogenase reductase Sdr
M479_1840	COG2920	part of a sulfur-relay system
M479_1844	COG1832	CoA-binding protein
M479_1845	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M479_1847	COG0210	DNA helicase
M479_1848	COG3304	Inner membrane component domain
M479_1849	COG1289	transmembrane transporter activity
M479_1850	COG3070	regulator of competence-specific genes
M479_1852	COG2885	chlorophyll binding
M479_1852	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M479_1853	COG1943	Transposase
M479_1855	COG1067	ATP-dependent peptidase activity
M479_1858	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M479_186	COG4807	Protein conserved in bacteria
M479_1860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M479_1861	COG1943	Transposase
M479_1863	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M479_1867	COG0681	Belongs to the peptidase S26 family
M479_1870	COG3086	response to oxidative stress
M479_1871	COG3026	antisigma factor binding
M479_1872	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
M479_1874	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M479_1876	COG0513	Belongs to the DEAD box helicase family
M479_1887	COG1984	allophanate hydrolase subunit 2
M479_1888	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M479_1890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M479_1891	COG5212	phosphodiesterase
M479_1893	COG3272	Protein of unknown function (DUF1722)
M479_1898	COG2205	protein histidine kinase activity
M479_1899	COG2205	protein histidine kinase activity
M479_190	COG1122	ATPase activity
M479_1900	COG0745	RESPONSE REGULATOR receiver
M479_1904	COG0033	Phosphoglucomutase
M479_1905	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
M479_1909	COG2169	Transcriptional regulator
M479_1909	COG1917	Cupin 2, conserved barrel domain protein
M479_191	COG0410	ABC transporter
M479_1910	COG1447	Phosphotransferase system cellobiose-specific component IIA
M479_1911	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M479_1912	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M479_1913	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M479_1914	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M479_1915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M479_1917	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
M479_1918	COG4413	Urea transporter
M479_1920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
M479_1927	COG1124	(ABC) transporter
M479_1928	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
M479_1929	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M479_1931	COG0747	negative chemotaxis
M479_1932	COG1278	Cold shock
M479_194	COG2897	thiosulfate sulfurtransferase activity
M479_1940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M479_1941	COG4175	Glycine betaine
M479_1942	COG4176	ABC-type proline glycine betaine transport system permease component
M479_1943	COG2113	Glycine betaine
M479_1945	COG1953	Uracil, thiamine, allantoin
M479_1947	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M479_1949	COG2226	methyltransferase
M479_195	COG1732	Glycine betaine
M479_1951	COG0741	lytic transglycosylase activity
M479_1951	COG1388	LysM domain
M479_1954	COG0656	L-ascorbic acid biosynthetic process
M479_196	COG1174	glycine betaine transport
M479_1960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M479_1962	COG2011	ABC-type metal ion transport system permease component
M479_1963	COG1464	Belongs to the NlpA lipoprotein family
M479_1965	COG1720	tRNA m6t6A37 methyltransferase activity
M479_1967	COG3015	lipoprotein NlpE involved in copper resistance
M479_1969	COG4681	YaeQ
M479_197	COG1125	glycine betaine transport
M479_1971	COG4568	rho-dependent transcription termination
M479_1973	COG0037	tRNA processing
M479_1974	COG0346	lactoylglutathione lyase activity
M479_1976	COG0587	DNA-directed DNA polymerase activity
M479_1978	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M479_198	COG1174	glycine betaine transport
M479_1982	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
M479_1984	COG0750	zinc metalloprotease
M479_1985	COG0575	Belongs to the CDS family
M479_1986	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M479_199	COG0531	amino acid
M479_1992	COG0024	Methionine aminopeptidase
M479_1997	COG0564	pseudouridine synthase activity
M479_1998	COG3098	single-species biofilm formation
M479_1999	COG1943	Transposase
M479_2	COG4953	penicillin-binding protein 1C
M479_20	COG5265	(ABC) transporter
M479_200	COG1982	Orn Lys Arg decarboxylase major
M479_2002	COG1611	Belongs to the LOG family
M479_2003	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M479_2005	COG2363	Small membrane protein
M479_2006	COG0583	DNA-binding transcription factor activity
M479_2008	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M479_2009	COG2166	iron-sulfur cluster assembly
M479_201	COG3328	transposase activity
M479_2010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M479_2011	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
M479_2014	COG0860	N-Acetylmuramoyl-L-alanine amidase
M479_2015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M479_2015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M479_2019	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M479_202	COG1982	Orn Lys Arg decarboxylase major
M479_2020	COG1074	ATP-dependent DNA helicase activity
M479_2022	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M479_2033	COG0667	Aldo Keto reductase
M479_2039	COG0019	diaminopimelate decarboxylase activity
M479_204	COG0697	spore germination
M479_2040	COG1609	Transcriptional regulator
M479_2041	COG2814	Major facilitator Superfamily
M479_2042	COG0583	DNA-binding transcription factor activity
M479_2043	COG0583	DNA-binding transcription factor activity
M479_2045	COG0840	transmembrane signaling receptor activity
M479_2049	COG3328	transposase activity
M479_2066	COG0288	reversible hydration of carbon dioxide
M479_2074	COG3119	arylsulfatase activity
M479_2075	COG1349	DNA-binding transcription factor activity
M479_2077	COG2222	sugar isomerase
M479_2078	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M479_2079	COG3715	PTS system
M479_2080	COG3716	PTS system mannose fructose sorbose family IID component
M479_2081	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_2083	COG1028	Short-chain dehydrogenase reductase Sdr
M479_2085	COG0641	radical SAM
M479_2086	COG3119	arylsulfatase activity
M479_2088	COG0191	fructose-bisphosphate aldolase activity
M479_209	COG0814	amino acid
M479_2092	COG2271	Major facilitator Superfamily
M479_2096	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M479_2096	COG1263	PTS System
M479_2097	COG1874	Beta-galactosidase
M479_2098	COG1874	Beta-galactosidase
M479_2099	COG3867	Arabinogalactan endo-beta-1,4-galactanase
M479_2100	COG3833	ABC-type maltose transport systems, permease component
M479_2101	COG1175	transmembrane transport
M479_2102	COG2182	Extracellular solute-binding protein
M479_2104	COG1129	ABC transporter
M479_2105	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_2106	COG1879	ABC-type sugar transport system periplasmic component
M479_2108	COG0791	NLP P60 protein
M479_2109	COG1695	Transcriptional regulator
M479_212	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M479_2126	COG2944	sequence-specific DNA binding
M479_2131	COG0582	viral genome integration into host DNA
M479_2135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M479_2136	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M479_2137	COG4974	Belongs to the 'phage' integrase family
M479_2138	COG0716	FMN binding
M479_2139	COG4452	Inner membrane protein CreD
M479_2140	COG2205	protein histidine kinase activity
M479_2141	COG0745	RESPONSE REGULATOR receiver
M479_2142	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M479_2145	COG1272	protein, Hemolysin III
M479_2147	COG5295	Hep Hag repeat protein
M479_2153	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M479_2154	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M479_2155	COG0006	proline dipeptidase activity
M479_2158	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M479_2159	COG1943	Transposase
M479_2160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M479_2161	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M479_2166	COG0191	fructose-bisphosphate aldolase activity
M479_217	COG2205	protein histidine kinase activity
M479_217	COG0784	Response regulator, receiver
M479_2170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M479_2171	COG0501	Belongs to the peptidase M48B family
M479_2173	COG1166	arginine decarboxylase activity
M479_2177	COG2356	endonuclease I
M479_2178	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M479_2179	COG0189	ligase activity
M479_2182	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M479_2184	COG2805	Type II/IV secretion system protein
M479_2185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M479_2186	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M479_2187	COG0762	integral membrane protein
M479_2189	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M479_219	COG2198	Histidine kinase
M479_219	COG0642	Histidine kinase
M479_2190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M479_2191	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
M479_2191	COG1073	alpha beta
M479_2191	COG3064	Membrane
M479_2194	COG2066	Belongs to the glutaminase family
M479_2195	COG3171	Protein conserved in bacteria
M479_2197	COG1194	a g-specific adenine glycosylase
M479_220	COG2198	Histidine kinase
M479_220	COG0642	Histidine kinase
M479_2201	COG4774	siderophore transport
M479_2202	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_2203	COG1129	ABC transporter
M479_2204	COG1879	ABC-type sugar transport system periplasmic component
M479_2205	COG1982	Orn Lys Arg decarboxylase major
M479_2209	COG1662	PFAM IS1 transposase
M479_221	COG2223	nitrite transmembrane transporter activity
M479_222	COG2223	nitrite transmembrane transporter activity
M479_2227	COG2771	luxR family
M479_2228	COG3916	Acyl-homoserine-lactone synthase
M479_2238	COG2211	Major facilitator Superfamily
M479_2239	COG2801	Transposase and inactivated derivatives
M479_224	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
M479_2241	COG3133	Outer membrane lipoprotein
M479_2246	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M479_2247	COG1191	sigma factor activity
M479_2252	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M479_2257	COG3710	Transcriptional regulator
M479_2261	COG1256	bacterial-type flagellum assembly
M479_2263	COG1706	bacterial-type flagellum-dependent cell motility
M479_2264	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
M479_2265	COG4786	Flagellar basal body rod
M479_2266	COG4787	bacterial-type flagellum-dependent cell motility
M479_2267	COG1749	Flagellar hook protein flgE
M479_2268	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M479_2269	COG1558	bacterial-type flagellum-dependent cell motility
M479_227	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M479_2270	COG1815	bacterial-type flagellum-dependent cell motility
M479_2271	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
M479_2280	COG2204	response regulator
M479_2284	COG1987	bacterial-type flagellum assembly
M479_2285	COG1684	flagellar biosynthetic protein fliR
M479_2286	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M479_2290	COG4592	Periplasmic binding protein
M479_2298	COG4964	Belongs to the GSP D family
M479_2299	COG4964	Belongs to the GSP D family
M479_2309	COG0848	biopolymer transport protein
M479_2311	COG0811	peptide transport
M479_2312	COG0626	cystathionine gamma-synthase activity
M479_2313	COG0586	Pfam SNARE associated Golgi protein
M479_2314	COG2207	Transcriptional regulator
M479_2315	COG1979	alcohol dehydrogenase
M479_2316	COG0656	L-ascorbic acid biosynthetic process
M479_2319	COG2132	Multicopper oxidase
M479_2320	COG0204	Acyl-transferase
M479_2321	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M479_2322	COG2249	NAD(P)H dehydrogenase (quinone) activity
M479_2323	COG0583	DNA-binding transcription factor activity
M479_2324	COG0187	DNA topoisomerase II activity
M479_2325	COG3150	esterase
M479_2326	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M479_2327	COG3151	Protein conserved in bacteria
M479_2328	COG0494	nUDIX hydrolase
M479_2329	COG1538	Outer membrane efflux protein
M479_2332	COG0754	glutathionylspermidine amidase activity
M479_2333	COG3384	dioxygenase
M479_2337	COG0531	amino acid
M479_2340	COG3025	triphosphatase activity
M479_2341	COG4991	sh3 domain protein
M479_2344	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M479_2348	COG0358	DNA primase activity
M479_2349	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M479_236	COG3395	kinase activity
M479_2366	COG0251	oxidation-reduction process
M479_237	COG0235	Class ii aldolase
M479_2374	COG1289	transmembrane transporter activity
M479_2378	COG0395	ABC-type sugar transport system, permease component
M479_238	COG1349	DNA-binding transcription factor activity
M479_2380	COG1653	transport
M479_2381	COG1609	Transcriptional regulator
M479_2382	COG3459	Glycosyltransferase 36 associated
M479_2383	COG3842	ATPase activity
M479_2387	COG3210	domain, Protein
M479_2389	COG3210	domain, Protein
M479_239	COG3622	Belongs to the hyi family
M479_2391	COG3210	domain, Protein
M479_2392	COG2831	hemolysin activation secretion protein
M479_2393	COG4245	von Willebrand factor, type A
M479_2396	COG4245	von Willebrand factor, type A
M479_2399	COG3247	response to pH
M479_2400	COG0446	pyridine nucleotide-disulphide oxidoreductase
M479_2400	COG1902	pentaerythritol trinitrate reductase activity
M479_2403	COG1451	nucleotide metabolic process
M479_2404	COG0673	inositol 2-dehydrogenase activity
M479_2407	COG1943	Transposase
M479_2409	COG2721	sulfolactate sulfo-lyase activity
M479_2410	COG0246	Mannitol dehydrogenase
M479_2412	COG2271	Major facilitator Superfamily
M479_2413	COG2271	Major facilitator Superfamily
M479_2416	COG0586	Pfam SNARE associated Golgi protein
M479_2419	COG4575	ribosome binding
M479_2420	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
M479_2422	COG2259	Doxx family
M479_2423	COG0435	Glutathione S-transferase
M479_2424	COG0583	DNA-binding transcription factor activity
M479_2425	COG1741	Belongs to the pirin family
M479_2426	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M479_243	COG4386	tail sheath protein
M479_2430	COG2823	Periplasmic or secreted lipoprotein
M479_2432	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
M479_2433	COG0784	Response regulator, receiver
M479_2433	COG5002	protein histidine kinase activity
M479_2433	COG2198	Histidine kinase
M479_2434	COG1242	4 iron, 4 sulfur cluster binding
M479_2435	COG0067	glutamate synthase
M479_2435	COG0070	glutamate synthase
M479_2435	COG0069	glutamate synthase activity
M479_2436	COG0493	'glutamate synthase
M479_2438	COG2969	positive regulation of protein catabolic process
M479_2439	COG0625	glutathione transferase activity
M479_2442	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M479_2443	COG3105	Protein conserved in bacteria
M479_2444	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M479_2445	COG1943	Transposase
M479_2446	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M479_2448	COG5007	Belongs to the BolA IbaG family
M479_2449	COG3113	response to antibiotic
M479_2450	COG2854	intermembrane phospholipid transfer
M479_2451	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M479_2452	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M479_2453	COG1127	ABC transporter
M479_2454	COG0530	calcium, potassium:sodium antiporter activity
M479_2455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M479_2455	COG0517	IMP dehydrogenase activity
M479_2456	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M479_2457	COG3117	lipopolysaccharide transmembrane transporter activity
M479_2458	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M479_2459	COG1137	ATPase activity
M479_2460	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M479_2462	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_2464	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_2470	COG1263	PTS System
M479_2470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M479_2471	COG0366	Alpha amylase catalytic
M479_2472	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M479_2473	COG3783	Cytochrome b(562)
M479_2475	COG0312	modulator of DNA gyrase
M479_2477	COG2732	(Barnase) inhibitor
M479_2480	COG1012	belongs to the aldehyde dehydrogenase family
M479_2484	COG0583	DNA-binding transcription factor activity
M479_2495	COG0312	modulator of DNA gyrase
M479_2496	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M479_2497	COG3164	Protein of unknown function
M479_2498	COG1530	ribonuclease E activity
M479_25	COG2197	response regulator
M479_2500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M479_2501	COG1792	Involved in formation and maintenance of cell shape
M479_2502	COG1077	Cell shape determining protein MreB Mrl
M479_2503	COG2200	EAL domain
M479_2503	COG2199	diguanylate cyclase activity
M479_2504	COG0604	alcohol dehydrogenase
M479_2505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M479_2508	COG0511	ligase activity, forming carbon-carbon bonds
M479_2509	COG0439	Biotin carboxylase
M479_2511	COG3924	membrane
M479_2512	COG4145	pantothenate transmembrane transporter activity
M479_2514	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M479_2515	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M479_2519	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M479_252	COG3299	homolog of phage Mu protein gp47
M479_2521	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M479_2522	COG3133	Outer membrane lipoprotein
M479_2523	COG1278	Cold shock
M479_2524	COG1278	Cold shock
M479_2525	COG1943	Transposase
M479_2528	COG0625	glutathione transferase activity
M479_2530	COG1069	ribulokinase activity
M479_2532	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_2533	COG1129	ABC transporter
M479_2535	COG1560	Kdo2-lipid A biosynthetic process
M479_2537	COG0025	NhaP-type Na H and K H
M479_2538	COG2252	PERMEase
M479_2539	COG3077	Addiction module antitoxin, RelB DinJ family
M479_2541	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M479_2543	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M479_2544	COG0431	NADPH-dependent FMN reductase
M479_2546	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M479_2547	COG1869	D-ribose catabolic process
M479_2548	COG1917	Cupin 2, conserved barrel domain protein
M479_2548	COG2207	Transcriptional regulator
M479_2549	COG0673	inositol 2-dehydrogenase activity
M479_2552	COG3209	COG3209 Rhs family protein
M479_2554	COG3501	Rhs element vgr protein
M479_256	COG1737	Transcriptional regulator
M479_2560	COG3209	COG3209 Rhs family protein
M479_2563	COG3501	Rhs element vgr protein
M479_2579	COG2801	Transposase and inactivated derivatives
M479_258	COG2723	6-phospho-beta-galactosidase activity
M479_2590	COG1175	transmembrane transport
M479_2591	COG3833	ABC-type maltose transport systems, permease component
M479_2594	COG0527	aspartate kinase activity
M479_2599	COG1414	Transcriptional regulator
M479_26	COG1278	Cold shock
M479_2601	COG2224	Isocitrate lyase
M479_2602	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M479_2613	COG0542	response to heat
M479_2615	COG0564	pseudouridine synthase activity
M479_2616	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M479_2617	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M479_2618	COG0077	Prephenate dehydratase
M479_2618	COG1605	Chorismate mutase
M479_2619	COG1605	Chorismate mutase
M479_2619	COG0287	Prephenate dehydrogenase
M479_262	COG3157	Type VI secretion system effector, Hcp
M479_2620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M479_2623	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M479_2624	COG3279	Response regulator of the LytR AlgR family
M479_2625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M479_2626	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M479_2627	COG3137	Salt-induced outer membrane protein
M479_2632	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M479_2633	COG4137	Cytochrome C assembly protein
M479_2634	COG4536	flavin adenine dinucleotide binding
M479_2636	COG2918	glutathione biosynthetic process
M479_2637	COG1238	metal cluster binding
M479_2638	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M479_2642	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
M479_2643	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M479_265	COG3083	sulfuric ester hydrolase activity
M479_2650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M479_2651	COG3958	Transketolase
M479_2652	COG3959	Transketolase, thiamine diphosphate binding domain
M479_2653	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_2654	COG1129	ABC transporter
M479_2658	COG3783	Cytochrome b(562)
M479_2659	COG3038	cytochrome b561
M479_266	COG3082	Protein of unknown function (DUF1414)
M479_2660	COG3381	protein complex oligomerization
M479_2661	COG3302	dmso reductase anchor subunit
M479_2662	COG0437	4 iron, 4 sulfur cluster binding
M479_2663	COG0243	molybdopterin cofactor binding
M479_2664	COG0235	Class ii aldolase
M479_2665	COG1349	DNA-binding transcription factor activity
M479_2667	COG1129	ABC transporter
M479_2668	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_2669	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_2670	COG3623	hexulose-6-phosphate isomerase
M479_2671	COG1070	Carbohydrate kinase
M479_2672	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M479_2672	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M479_2674	COG0024	Methionine aminopeptidase
M479_2676	COG4771	TonB-dependent receptor
M479_2678	COG1858	cytochrome C peroxidase
M479_2679	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M479_268	COG1943	Transposase
M479_2683	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M479_2686	COG2376	Dihydroxyacetone kinase
M479_2687	COG1028	Short-chain dehydrogenase reductase Sdr
M479_2688	COG1063	alcohol dehydrogenase
M479_2689	COG0698	ribose 5-phosphate isomerase
M479_2690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
M479_2691	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M479_2692	COG4942	peptidase
M479_2692	COG1388	LysM domain
M479_2697	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M479_27	COG1278	Cold shock
M479_270	COG1061	Type III restriction enzyme res subunit
M479_2700	COG0529	Catalyzes the synthesis of activated sulfate
M479_271	COG1187	pseudouridine synthase activity
M479_2711	COG0720	synthase
M479_2712	COG0602	queuosine metabolic process
M479_2716	COG3956	TIGRFAM MazG family protein
M479_2717	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M479_2718	COG2205	protein histidine kinase activity
M479_2718	COG4999	Histidine kinase
M479_2718	COG3850	Histidine kinase
M479_2718	COG3437	response regulator, receiver
M479_2719	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M479_272	COG2814	Major facilitator Superfamily
M479_2721	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M479_2723	COG2860	membrane
M479_2727	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M479_2728	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M479_2729	COG1120	ATPase activity
M479_2730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M479_2731	COG1643	Atp-dependent helicase
M479_2732	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M479_2734	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M479_2735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M479_2736	COG0617	tRNA 3'-terminal CCA addition
M479_2737	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M479_274	COG4172	Belongs to the ABC transporter superfamily
M479_2741	COG0726	polysaccharide deacetylase
M479_2743	COG0842	Transport permease protein
M479_2744	COG1131	(ABC) transporter
M479_2745	COG0288	reversible hydration of carbon dioxide
M479_2746	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M479_2747	COG2132	Multicopper oxidase
M479_275	COG4239	(ABC) transporter, permease
M479_2751	COG0697	spore germination
M479_2753	COG1049	propionate catabolic process, 2-methylcitrate cycle
M479_2754	COG1943	Transposase
M479_2755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M479_2756	COG0508	dehydrogenase complex catalyzes the overall conversion of
M479_2757	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
M479_2758	COG2186	Transcriptional regulator
M479_2759	COG1113	amino acid transport
M479_276	COG4174	ABC transporter (Permease)
M479_2760	COG3725	Membrane protein required for beta-lactamase induction
M479_2761	COG3023	N-Acetylmuramoyl-L-alanine amidase
M479_2763	COG4969	Belongs to the N-Me-Phe pilin family
M479_2764	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M479_2765	COG1459	type II secretion system
M479_2767	COG0237	dephospho-CoA kinase activity
M479_277	COG4166	transmembrane transport
M479_2774	COG0494	nUDIX hydrolase
M479_2779	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M479_278	COG2200	EAL domain
M479_2780	COG0849	cell division
M479_2781	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M479_2785	COG0772	Belongs to the SEDS family
M479_2788	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M479_2789	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M479_2790	COG0768	penicillin binding
M479_2791	COG3116	cell division
M479_2796	COG1609	Transcriptional regulator
M479_2797	COG1943	Transposase
M479_2799	COG0028	Belongs to the TPP enzyme family
M479_28	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M479_280	COG0791	NLP P60 protein
M479_2800	COG3328	transposase activity
M479_2801	COG1022	Amp-dependent synthetase and ligase
M479_2805	COG0473	3-isopropylmalate dehydrogenase activity
M479_2808	COG2814	Major facilitator Superfamily
M479_281	COG0671	phosphoesterase, PA-phosphatase related
M479_2811	COG4143	(ABC) transporter
M479_2812	COG1178	ABC-type Fe3 transport system permease component
M479_2814	COG0586	Pfam SNARE associated Golgi protein
M479_2815	COG0417	DNA replication proofreading
M479_2819	COG3047	cAMP biosynthetic process
M479_2819	COG2885	chlorophyll binding
M479_282	COG0523	cobalamin synthesis protein
M479_2826	COG3501	Rhs element vgr protein
M479_2836	COG0564	pseudouridine synthase activity
M479_2837	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
M479_2839	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M479_284	COG2186	Transcriptional regulator
M479_2840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
M479_2845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M479_2847	COG2966	Psort location CytoplasmicMembrane, score
M479_2848	COG1280	lysine exporter protein (LysE YggA)
M479_2849	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M479_285	COG0246	Mannitol dehydrogenase
M479_2850	COG0505	Belongs to the CarA family
M479_2853	COG1047	Peptidyl-prolyl cis-trans
M479_2856	COG0196	riboflavin kinase activity
M479_2858	COG0583	DNA-binding transcription factor activity
M479_286	COG1312	Catalyzes the dehydration of D-mannonate
M479_2862	COG1584	GPR1 FUN34 yaaH family protein
M479_2865	COG0521	Mo-molybdopterin cofactor biosynthetic process
M479_2873	COG0745	RESPONSE REGULATOR receiver
M479_2874	COG3045	CreA protein
M479_2877	COG3708	Transcriptional regulator
M479_2877	COG2207	Transcriptional regulator
M479_2878	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
M479_2880	COG0741	lytic transglycosylase activity
M479_2883	COG2199	diguanylate cyclase activity
M479_2884	COG2885	chlorophyll binding
M479_2885	COG0488	(ABC) transporter
M479_2890	COG0560	Phosphoserine phosphatase
M479_2891	COG3726	membrane protein affecting hemolysin expression
M479_2895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M479_2896	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M479_2897	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M479_2898	COG0084	hydrolase, TatD family'
M479_2899	COG4667	esterase of the alpha-beta hydrolase superfamily
M479_29	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M479_290	COG1028	Short-chain dehydrogenase reductase Sdr
M479_2901	COG2823	Periplasmic or secreted lipoprotein
M479_2903	COG0456	acetyltransferase
M479_2904	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
M479_2908	COG3706	GGDEF domain
M479_2911	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M479_2912	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M479_2915	COG0859	PFAM glycosyl transferase family 9
M479_2917	COG2390	Transcriptional regulator
M479_2925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M479_2925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_2925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_2926	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M479_2927	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M479_2928	COG2207	Transcriptional regulator
M479_2929	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M479_2931	COG4269	membrane
M479_2941	COG2963	transposase activity
M479_2943	COG1401	restriction endodeoxyribonuclease activity
M479_2948	COG0582	viral genome integration into host DNA
M479_295	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M479_2950	COG0795	lipopolysaccharide-transporting ATPase activity
M479_2951	COG0795	lipopolysaccharide-transporting ATPase activity
M479_2953	COG2927	DNA polymerase III (CHI subunit)
M479_2954	COG0525	valine-tRNA ligase activity
M479_2956	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
M479_2957	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M479_2958	COG2731	YhcH YjgK YiaL family protein
M479_2961	COG0601	transmembrane transport
M479_2962	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M479_2963	COG0444	Belongs to the ABC transporter superfamily
M479_2964	COG4608	Belongs to the ABC transporter superfamily
M479_2968	COG2188	Transcriptional regulator
M479_2969	COG3624	Phosphonate C-P lyase system protein PhnG
M479_297	COG1129	ABC transporter
M479_2970	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
M479_2971	COG3626	phosphonate metabolism
M479_2972	COG3627	carbon phosphorus lyase activity
M479_2973	COG4107	phosphonate C-P lyase system protein PhnK
M479_2974	COG4778	phosphonate C-P lyase system protein PhnL
M479_2975	COG3454	Phosphonate metabolism
M479_2976	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
M479_2977	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M479_2978	COG0702	epimerase
M479_298	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_2981	COG3842	ATPase activity
M479_2982	COG0395	ABC-type sugar transport system, permease component
M479_2984	COG1653	transport
M479_2988	COG3153	acetyltransferase
M479_299	COG0494	nUDIX hydrolase
M479_2993	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M479_2996	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M479_2999	COG0513	Belongs to the DEAD box helicase family
M479_3	COG2373	Large extracellular alpha-helical protein
M479_3003	COG2801	Transposase and inactivated derivatives
M479_3006	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M479_3007	COG0058	SHG alpha-glucan phosphorylase activity
M479_3009	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M479_301	COG1105	Belongs to the carbohydrate kinase PfkB family
M479_3012	COG3275	phosphorelay sensor kinase activity
M479_3018	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M479_3019	COG2095	MarC family integral membrane protein
M479_302	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M479_302	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M479_302	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M479_3023	COG3265	gluconokinase activity
M479_3024	COG2610	gluconate transmembrane transporter activity
M479_3025	COG1609	Transcriptional regulator
M479_3026	COG1609	Transcriptional regulator
M479_3027	COG1741	Belongs to the pirin family
M479_3029	COG0745	RESPONSE REGULATOR receiver
M479_303	COG3710	Transcriptional regulator
M479_3031	COG0191	fructose-bisphosphate aldolase activity
M479_3033	COG1879	ABC-type sugar transport system periplasmic component
M479_3034	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_3037	COG2081	HI0933 family
M479_3038	COG0306	phosphate transporter
M479_3041	COG0589	response to stress
M479_3045	COG0339	signal peptide processing
M479_3046	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M479_3047	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M479_3048	COG3835	regulator
M479_3049	COG2610	gluconate transmembrane transporter activity
M479_3050	COG1929	Belongs to the glycerate kinase type-1 family
M479_3055	COG1295	ribonuclease BN
M479_3056	COG2134	cdp-diacylglycerol pyrophosphatase
M479_3057	COG2982	Protein involved in outer membrane biogenesis
M479_3058	COG2200	EAL domain
M479_3059	COG1942	4-Oxalocrotonate Tautomerase
M479_306	COG3121	Chaperone
M479_3060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M479_3061	COG0612	Peptidase, M16
M479_3066	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M479_3067	COG2200	EAL domain
M479_3067	COG2199	diguanylate cyclase activity
M479_3068	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M479_3069	COG4608	Belongs to the ABC transporter superfamily
M479_307	COG3188	usher protein
M479_3070	COG0444	Belongs to the ABC transporter superfamily
M479_3071	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M479_3072	COG0601	transmembrane transport
M479_3073	COG0747	negative chemotaxis
M479_3075	COG2831	hemolysin activation secretion protein
M479_3079	COG2271	Major facilitator Superfamily
M479_3080	COG3851	Histidine kinase
M479_3081	COG2197	response regulator
M479_3082	COG2194	sulfuric ester hydrolase activity
M479_3086	COG3650	response to hydrogen peroxide
M479_3087	COG1960	acyl-CoA dehydrogenase activity
M479_3088	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M479_3089	COG0557	exoribonuclease II activity
M479_309	COG2855	membrane
M479_3092	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
M479_3093	COG0330	HflC and HflK could
M479_3094	COG0330	HflC and HflK could
M479_3095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M479_3099	COG0860	N-Acetylmuramoyl-L-alanine amidase
M479_310	COG0583	DNA-binding transcription factor activity
M479_3100	COG0802	atpase or kinase
M479_3101	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M479_3101	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M479_3102	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M479_3105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M479_3108	COG1511	domain protein
M479_3108	COG3264	Mechanosensitive ion channel
M479_3110	COG1053	succinate dehydrogenase
M479_3111	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M479_3113	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
M479_3114	COG2076	Multidrug Resistance protein
M479_312	COG0833	amino acid
M479_3122	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M479_3125	COG3383	formate dehydrogenase (NAD+) activity
M479_3126	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M479_3127	COG0493	'glutamate synthase
M479_3127	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M479_3128	COG1309	transcriptional regulator
M479_3143	COG1454	alcohol dehydrogenase
M479_3145	COG0629	single-stranded DNA binding
M479_3146	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M479_3147	COG2315	Protein conserved in bacteria
M479_3148	COG1448	Aminotransferase
M479_3149	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M479_315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M479_3150	COG0305	Participates in initiation and elongation during chromosome replication
M479_3153	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M479_3154	COG0735	belongs to the Fur family
M479_3156	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M479_3165	COG3121	Chaperone
M479_317	COG4771	TonB-dependent receptor
M479_3177	COG1358	cellular component organization or biogenesis
M479_318	COG0625	glutathione transferase activity
M479_3182	COG3721	Heme iron utilization protein
M479_3183	COG0702	epimerase
M479_3185	COG4771	TonB-dependent receptor
M479_3186	COG3720	iron ion transport
M479_3187	COG4558	Periplasmic binding protein
M479_3188	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M479_3190	COG0626	cystathionine gamma-synthase activity
M479_3191	COG0814	amino acid
M479_3192	COG0583	DNA-binding transcription factor activity
M479_3193	COG0425	Belongs to the sulfur carrier protein TusA family
M479_3194	COG2391	methyltransferase activity
M479_3216	COG1301	dicarboxylic acid transport
M479_3218	COG3162	membrane
M479_3224	COG2801	Transposase and inactivated derivatives
M479_3231	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M479_3234	COG0551	DNA topoisomerase type I activity
M479_3236	COG0758	DNA mediated transformation
M479_324	COG2011	ABC-type metal ion transport system permease component
M479_3240	COG0569	domain protein
M479_3242	COG3036	rescue of stalled ribosome
M479_3243	COG0789	Transcriptional regulator
M479_3246	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M479_3249	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M479_325	COG1686	Belongs to the peptidase S11 family
M479_3250	COG0201	protein transport
M479_3252	COG1841	ribosomal large subunit assembly
M479_326	COG0814	amino acid
M479_3260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M479_3261	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M479_3263	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M479_3264	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
M479_3266	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
M479_327	COG1349	DNA-binding transcription factor activity
M479_3271	COG0051	transcription antitermination factor activity, RNA binding
M479_3274	COG1943	Transposase
M479_3277	COG0049	tRNA binding
M479_328	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M479_3282	COG2964	Protein conserved in bacteria
M479_3283	COG0545	Peptidyl-prolyl cis-trans isomerase
M479_3285	COG1047	Peptidyl-prolyl cis-trans
M479_3286	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M479_3289	COG0488	(ABC) transporter
M479_329	COG0671	phosphoesterase, PA-phosphatase related
M479_3290	COG1216	Glycosyl transferase, family 2
M479_3293	COG2175	clavaminate synthase activity
M479_3294	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M479_3296	COG4521	taurine ABC transporter
M479_3298	COG0429	hydrolase of the alpha beta-hydrolase fold
M479_33	COG1686	Belongs to the peptidase S11 family
M479_3300	COG3954	Phosphoribulokinase
M479_3302	COG1765	OsmC-like protein
M479_3304	COG1289	transmembrane transporter activity
M479_3307	COG0433	COG0433 Predicted ATPase
M479_3308	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M479_3309	COG1486	melibiose metabolic process
M479_331	COG2985	domain, Protein
M479_331	COG0569	domain protein
M479_3313	COG0402	S-adenosylhomocysteine deaminase activity
M479_3314	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M479_3315	COG2146	nitrite reductase [NAD(P)H] activity
M479_3318	COG0180	Tryptophanyl-tRNA synthetase
M479_3319	COG0546	phosphoglycolate phosphatase activity
M479_332	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M479_3320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M479_3325	COG4796	Type ii and iii secretion system protein
M479_3330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M479_3331	COG0494	nUDIX hydrolase
M479_3334	COG1011	Hydrolase
M479_3335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M479_3339	COG0745	RESPONSE REGULATOR receiver
M479_3340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M479_3341	COG2183	response to ionizing radiation
M479_3342	COG1918	ferrous iron import across plasma membrane
M479_3349	COG1640	4-alpha-glucanotransferase
M479_335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M479_3350	COG0058	SHG alpha-glucan phosphorylase activity
M479_3354	COG1349	DNA-binding transcription factor activity
M479_3356	COG2801	Transposase and inactivated derivatives
M479_336	COG3842	ATPase activity
M479_3361	COG3328	transposase activity
M479_3363	COG3276	selenocysteine insertion sequence binding
M479_3366	COG2864	formate dehydrogenase
M479_3367	COG0437	4 iron, 4 sulfur cluster binding
M479_3368	COG0243	molybdopterin cofactor binding
M479_3368	COG3383	formate dehydrogenase (NAD+) activity
M479_3369	COG0243	molybdopterin cofactor binding
M479_3369	COG3383	formate dehydrogenase (NAD+) activity
M479_337	COG1176	ABC-type spermidine putrescine transport system, permease component I
M479_3371	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M479_3378	COG3722	fumarate hydratase activity
M479_338	COG1177	transmembrane transport
M479_3380	COG2213	PTS system mannitol-specific
M479_3380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_3385	COG2818	Glycosylase
M479_3387	COG2885	chlorophyll binding
M479_3390	COG0366	Alpha amylase catalytic
M479_3392	COG3977	Valine--pyruvate aminotransferase
M479_3396	COG5645	(Lipo)protein
M479_3397	COG0823	Involved in the tonB-independent uptake of proteins
M479_3398	COG0823	Involved in the tonB-independent uptake of proteins
M479_3399	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M479_34	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M479_3400	COG2423	ornithine cyclodeaminase activity
M479_3402	COG2801	Transposase and inactivated derivatives
M479_3403	COG0561	phosphatase activity
M479_3404	COG0187	DNA topoisomerase II activity
M479_3405	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
M479_3406	COG0592	DNA-directed DNA polymerase activity
M479_3409	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M479_3412	COG0706	membrane insertase activity
M479_3417	COG2252	PERMEase
M479_3418	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M479_3419	COG0765	amino acid transport
M479_3420	COG0765	amino acid transport
M479_3421	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M479_3423	COG0704	Plays a role in the regulation of phosphate uptake
M479_3425	COG0581	inorganic phosphate transmembrane transporter activity
M479_3426	COG0573	inorganic phosphate transmembrane transporter activity
M479_3427	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M479_3428	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M479_3438	COG3312	ion transport
M479_3441	COG0716	FMN binding
M479_3442	COG1522	sequence-specific DNA binding
M479_3448	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M479_3449	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M479_345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M479_3450	COG0477	Major facilitator Superfamily
M479_3452	COG2186	Transcriptional regulator
M479_3457	COG3328	transposase activity
M479_3458	COG1763	Mo-molybdopterin cofactor biosynthetic process
M479_346	COG1120	ATPase activity
M479_3460	COG3084	Protein conserved in bacteria
M479_3461	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M479_3462	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M479_3463	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M479_3463	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M479_3466	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M479_3468	COG3852	Histidine kinase
M479_3469	COG0174	glutamine synthetase
M479_3471	COG1011	Hydrolase
M479_3472	COG1295	ribonuclease BN
M479_3476	COG0456	acetyltransferase
M479_3477	COG2982	Protein involved in outer membrane biogenesis
M479_3478	COG2233	PERMEase
M479_3479	COG0786	glutamate:sodium symporter activity
M479_3480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M479_3481	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M479_3482	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M479_3485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M479_3486	COG2860	membrane
M479_3487	COG1561	YicC-like family, N-terminal region
M479_3492	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M479_3495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M479_3499	COG1519	Transferase
M479_35	COG0772	Belongs to the SEDS family
M479_350	COG4160	amino acid transport
M479_3500	COG0859	PFAM glycosyl transferase family 9
M479_3501	COG0859	PFAM glycosyl transferase family 9
M479_3503	COG0156	8-amino-7-oxononanoate synthase activity
M479_3505	COG2861	carbohydrate metabolic process
M479_3506	COG2861	carbohydrate metabolic process
M479_3507	COG4942	peptidase
M479_3509	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M479_351	COG4215	(ABC) transporter
M479_3510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M479_3513	COG1045	serine acetyltransferase
M479_3514	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M479_3515	COG2169	Transcriptional regulator
M479_3515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M479_3516	COG2205	protein histidine kinase activity
M479_3517	COG0745	RESPONSE REGULATOR receiver
M479_3518	COG3678	ATP-independent chaperone mediated protein folding
M479_352	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M479_3523	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M479_3525	COG0471	metal ion transport
M479_3526	COG0471	metal ion transport
M479_3527	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M479_3528	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M479_3529	COG0583	DNA-binding transcription factor activity
M479_353	COG1126	abc transporter atp-binding protein
M479_3532	COG3152	Membrane
M479_3534	COG1494	fructose-1,6-bisphosphatase
M479_3535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M479_3536	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M479_354	COG1605	Chorismate mutase
M479_3544	COG1575	Belongs to the MenA family. Type 1 subfamily
M479_3547	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M479_3548	COG1609	Transcriptional regulator
M479_3550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M479_3552	COG4682	membrane
M479_3554	COG0626	cystathionine gamma-synthase activity
M479_3555	COG0460	homoserine dehydrogenase
M479_3555	COG0527	aspartate kinase activity
M479_3557	COG2801	Transposase and inactivated derivatives
M479_356	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M479_3560	COG3274	enterobacterial common antigen metabolic process
M479_3562	COG3188	usher protein
M479_3563	COG3188	usher protein
M479_3564	COG3121	Chaperone
M479_3566	COG1070	Carbohydrate kinase
M479_3568	COG4213	ABC transporter substrate-binding protein
M479_357	COG0702	epimerase
M479_3570	COG4214	carbohydrate transport
M479_3571	COG2207	Transcriptional regulator
M479_3571	COG1609	Transcriptional regulator
M479_3573	COG0582	viral genome integration into host DNA
M479_358	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
M479_3580	COG4604	ABC transporter, ATP-binding protein
M479_3582	COG4605	iron ion homeostasis
M479_3584	COG4607	ABC-type enterochelin transport system periplasmic component
M479_3587	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M479_359	COG0028	Belongs to the TPP enzyme family
M479_3590	COG2986	histidine ammonia-lyase
M479_36	COG0768	penicillin binding
M479_360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M479_3601	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M479_3602	COG0250	Participates in transcription elongation, termination and antitermination
M479_3610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
M479_3615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M479_3617	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
M479_362	COG2431	L-lysine efflux transmembrane transporter activity
M479_3622	COG1515	deoxyribonuclease V activity
M479_3623	COG3068	Protein conserved in bacteria
M479_3626	COG0151	Belongs to the GarS family
M479_363	COG3593	DNA synthesis involved in DNA repair
M479_3636	COG1879	ABC-type sugar transport system periplasmic component
M479_3637	COG1129	ABC transporter
M479_3638	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_364	COG2990	Protein conserved in bacteria
M479_3640	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_3641	COG3085	chromosome segregation
M479_3644	COG3978	acetolactate synthase activity
M479_3645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M479_365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M479_3653	COG0583	DNA-binding transcription factor activity
M479_3660	COG3121	Chaperone
M479_3663	COG3121	Chaperone
M479_3666	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M479_367	COG1278	Cold shock
M479_3670	COG3118	belongs to the thioredoxin family
M479_3671	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M479_3672	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M479_3673	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M479_3674	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M479_3675	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M479_3676	COG1088	dTDP-glucose 4,6-dehydratase activity
M479_3677	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M479_3678	COG0456	acetyltransferase
M479_3679	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M479_3680	COG2244	polysaccharide biosynthetic process
M479_3684	COG1113	amino acid transport
M479_369	COG0542	response to heat
M479_3691	COG3071	HemY protein
M479_3692	COG2959	enzyme of heme biosynthesis
M479_3693	COG1587	Uroporphyrinogen-III synthase
M479_3695	COG3072	Adenylate cyclase
M479_3697	COG5567	small periplasmic lipoprotein
M479_3699	COG3159	Protein conserved in bacteria
M479_3700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M479_3701	COG1011	Hydrolase
M479_3702	COG0210	DNA helicase
M479_3704	COG5441	Belongs to the UPF0261 family
M479_3705	COG5564	TIM-barrel signal transduction protein
M479_3706	COG0598	Magnesium transport protein CorA
M479_3708	COG2050	protein possibly involved in aromatic compounds catabolism
M479_3709	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
M479_371	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
M479_3710	COG0514	ATP-dependent DNA helicase (RecQ)
M479_3711	COG1280	lysine exporter protein (LysE YggA)
M479_3712	COG1280	lysine exporter protein (LysE YggA)
M479_3713	COG2267	carboxylic ester hydrolase activity
M479_3714	COG0561	phosphatase activity
M479_3716	COG0584	glycerophosphoryl diester phosphodiesterase
M479_3717	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M479_3719	COG0247	lactate metabolic process
M479_3721	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M479_3724	COG3714	YhhN family
M479_3727	COG3776	membrane
M479_3728	COG0742	ribosomal rna small subunit methyltransferase
M479_3729	COG0552	protein localization to endoplasmic reticulum
M479_3729	COG0552	protein localization to endoplasmic reticulum
M479_373	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M479_3730	COG2884	Cell division ATP-binding protein ftsE
M479_3731	COG2177	Part of the ABC transporter FtsEX involved in
M479_3733	COG1943	Transposase
M479_3735	COG0683	leucine binding
M479_3736	COG0559	Belongs to the binding-protein-dependent transport system permease family
M479_3737	COG4177	L-phenylalanine transmembrane transporter activity
M479_3738	COG0411	ABC transporter
M479_3739	COG0410	ABC transporter
M479_375	COG0492	ferredoxin-NADP+ reductase activity
M479_3751	COG0584	glycerophosphoryl diester phosphodiesterase
M479_3752	COG0679	Auxin Efflux Carrier
M479_3753	COG0583	DNA-binding transcription factor activity
M479_3756	COG0412	Dienelactone hydrolase
M479_3757	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
M479_3759	COG1966	Carbon starvation protein
M479_3760	COG0586	Pfam SNARE associated Golgi protein
M479_3761	COG1322	Protein conserved in bacteria
M479_3765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M479_3767	COG0805	protein transport
M479_377	COG3107	peptidoglycan biosynthetic process
M479_377	COG1674	ftsk spoiiie
M479_3776	COG1739	Uncharacterized protein family UPF0029
M479_3777	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M479_3778	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
M479_3784	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M479_3790	COG1073	alpha beta
M479_3793	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M479_3795	COG1943	Transposase
M479_3797	COG3061	Opacity-associated protein A
M479_3798	COG0545	Peptidyl-prolyl cis-trans isomerase
M479_38	COG0799	negative regulation of ribosome biogenesis
M479_380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M479_3800	COG0737	Belongs to the 5'-nucleotidase family
M479_3802	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
M479_3804	COG1253	flavin adenine dinucleotide binding
M479_3806	COG0729	surface antigen
M479_3807	COG2911	Protein conserved in bacteria
M479_3808	COG2105	PFAM AIG2 family protein
M479_3809	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M479_3811	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M479_3815	COG3423	Transcriptional regulator
M479_3817	COG0142	geranyltranstransferase activity
M479_382	COG2814	Major facilitator Superfamily
M479_3820	COG0697	spore germination
M479_3822	COG0642	Histidine kinase
M479_3823	COG0745	RESPONSE REGULATOR receiver
M479_3824	COG2027	D-alanyl-D-alanine carboxypeptidase
M479_3825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M479_3826	COG1534	Rna-binding protein
M479_3828	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M479_3829	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M479_383	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M479_3831	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M479_3835	COG0195	Participates in both transcription termination and antitermination
M479_3840	COG2801	Transposase and inactivated derivatives
M479_3844	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
M479_3848	COG1629	transport
M479_385	COG1882	Formate acetyltransferase
M479_3853	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M479_3854	COG0678	peroxiredoxin activity
M479_3854	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M479_386	COG2116	formate transmembrane transporter activity
M479_3868	COG5544	Lipoprotein
M479_3869	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M479_387	COG1944	ATP diphosphatase activity
M479_3870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M479_3870	COG0045	succinate-CoA ligase (ADP-forming) activity
M479_3870	COG1042	CoA-binding domain protein
M479_3872	COG3118	belongs to the thioredoxin family
M479_3873	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M479_3874	COG2814	Major facilitator Superfamily
M479_3875	COG1566	PFAM secretion protein HlyD family protein
M479_3876	COG1846	Transcriptional regulator
M479_3878	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M479_3879	COG2814	Major facilitator Superfamily
M479_388	COG0252	asparaginase activity
M479_3888	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M479_389	COG5295	Hep Hag repeat protein
M479_389	COG5295	Hep Hag repeat protein
M479_3891	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M479_3894	COG0436	Aminotransferase
M479_3902	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
M479_3905	COG1960	acyl-CoA dehydrogenase activity
M479_3907	COG3034	peptidoglycan biosynthetic process
M479_3908	COG0121	glutamine amidotransferase
M479_3909	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M479_3910	COG1805	sodium ion transport
M479_3911	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M479_3915	COG1477	protein flavinylation
M479_3919	COG2195	Cleaves the N-terminal amino acid of tripeptides
M479_3930	COG2226	methyltransferase
M479_3935	COG1940	carbohydrate kinase activity
M479_3936	COG0419	ATPase involved in DNA repair
M479_3937	COG0420	3'-5' exonuclease activity
M479_3938	COG0745	RESPONSE REGULATOR receiver
M479_3939	COG5002	protein histidine kinase activity
M479_394	COG0539	negative regulation of cytoplasmic translation
M479_3941	COG1114	Component of the transport system for branched-chain amino acids
M479_3943	COG0366	Alpha amylase catalytic
M479_3947	COG0450	alkyl hydroperoxide reductase
M479_3948	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
M479_3949	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
M479_3951	COG1862	Preprotein translocase
M479_3952	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M479_3953	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M479_3958	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M479_3958	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M479_3961	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M479_3962	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M479_3965	COG0142	geranyltranstransferase activity
M479_3968	COG0693	protein deglycase activity
M479_3969	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M479_397	COG0658	competence protein
M479_397	COG2333	competence protein COMEC
M479_3971	COG2814	Major facilitator Superfamily
M479_3973	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M479_3974	COG1845	cytochrome c oxidase, subunit III
M479_3975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M479_3976	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M479_3978	COG2223	nitrite transmembrane transporter activity
M479_3979	COG3056	Lipoprotein
M479_3980	COG0271	Belongs to the BolA IbaG family
M479_3985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M479_3986	COG0776	regulation of translation
M479_3988	COG1943	Transposase
M479_3989	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M479_3990	COG1555	photosystem II stabilization
M479_3991	COG0824	Thioesterase
M479_3993	COG4533	DNA binding
M479_3996	COG1522	sequence-specific DNA binding
M479_3997	COG1132	(ABC) transporter
M479_3998	COG1132	(ABC) transporter
M479_3999	COG0347	Belongs to the P(II) protein family
M479_40	COG1466	dna polymerase III delta subunit
M479_400	COG5383	Protein conserved in bacteria
M479_4000	COG0004	ammonium transporteR
M479_4001	COG1946	Acyl-CoA thioesterase
M479_4002	COG3126	Type III secretion system lipoprotein chaperone (YscW)
M479_4003	COG3695	enzyme binding
M479_4007	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M479_4009	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M479_401	COG1278	Cold shock
M479_4010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M479_4011	COG1309	transcriptional regulator
M479_4012	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M479_4013	COG1196	nuclear chromosome segregation
M479_4013	COG3264	Mechanosensitive ion channel
M479_4015	COG2832	Protein of unknown function (DUF454)
M479_4017	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M479_402	COG2835	tetraacyldisaccharide 4'-kinase activity
M479_4023	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M479_4023	COG0543	2 iron, 2 sulfur cluster binding
M479_4027	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M479_4035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
M479_4036	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
M479_4037	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M479_404	COG3173	Aminoglycoside phosphotransferase
M479_4041	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M479_4042	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M479_4043	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M479_4043	COG4651	solute:proton antiporter activity
M479_4044	COG2223	nitrite transmembrane transporter activity
M479_4045	COG2223	nitrite transmembrane transporter activity
M479_4046	COG0737	Belongs to the 5'-nucleotidase family
M479_4047	COG0737	Belongs to the 5'-nucleotidase family
M479_4048	COG0737	Belongs to the 5'-nucleotidase family
M479_405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M479_4051	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M479_4052	COG3735	TraB family
M479_4053	COG2217	Heavy metal translocating P-type atpase
M479_4054	COG0789	Transcriptional regulator
M479_4055	COG1585	Membrane protein implicated in regulation of membrane protease activity
M479_4056	COG0330	HflC and HflK could
M479_4057	COG3118	belongs to the thioredoxin family
M479_4058	COG0300	oxidoreductase activity
M479_4059	COG2755	lipolytic protein G-D-S-L family
M479_406	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
M479_4060	COG4181	ATPase activity
M479_4061	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M479_4062	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M479_4063	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M479_4065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M479_4068	COG1943	Transposase
M479_4069	COG2501	S4 domain
M479_407	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
M479_4076	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M479_4077	COG4589	Belongs to the CDS family
M479_4079	COG2267	carboxylic ester hydrolase activity
M479_4080	COG2453	phosphatase
M479_4080	COG0671	phosphoesterase, PA-phosphatase related
M479_4089	COG0667	Aldo Keto reductase
M479_4090	COG0656	L-ascorbic acid biosynthetic process
M479_4095	COG3328	transposase activity
M479_4096	COG2850	peptidyl-arginine hydroxylation
M479_410	COG2989	Protein conserved in bacteria
M479_4106	COG5301	cellulose 1,4-beta-cellobiosidase activity
M479_4106	COG5301	cellulose 1,4-beta-cellobiosidase activity
M479_4107	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
M479_411	COG3108	Peptidase M15
M479_4110	COG1475	DNA binding
M479_412	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M479_4126	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M479_413	COG1448	Aminotransferase
M479_4132	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M479_4132	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M479_4137	COG3328	transposase activity
M479_4160	COG3328	transposase activity
M479_417	COG0308	aminopeptidase N
M479_4184	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M479_4186	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M479_4197	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M479_420	COG3217	Mosc domain protein beta barrel domain protein
M479_420	COG0633	Ferredoxin
M479_4203	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M479_4204	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M479_4206	COG1943	Transposase
M479_4216	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M479_4217	COG1475	DNA binding
M479_4218	COG1475	DNA binding
M479_422	COG0488	(ABC) transporter
M479_423	COG2995	paraquat-inducible protein a
M479_4237	COG3941	tape measure
M479_424	COG3008	intermembrane lipid transfer
M479_424	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M479_4249	COG4669	(LipO)protein
M479_425	COG3009	Protein conserved in bacteria
M479_4251	COG1317	bacterial-type flagellum organization
M479_4252	COG5599	Phosphatase
M479_4253	COG2963	transposase activity
M479_4254	COG2801	Transposase and inactivated derivatives
M479_426	COG1943	Transposase
M479_4260	COG2801	Transposase and inactivated derivatives
M479_4262	COG0515	serine threonine protein kinase
M479_427	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M479_428	COG1737	Transcriptional regulator
M479_4280	COG2801	Transposase and inactivated derivatives
M479_4285	COG2801	Transposase and inactivated derivatives
M479_4289	COG2801	Transposase and inactivated derivatives
M479_4291	COG5599	Phosphatase
M479_4293	COG3609	addiction module antidote protein, CC2985 family
M479_4295	COG1475	DNA binding
M479_4296	COG1192	Involved in chromosome partitioning
M479_4298	COG2801	Transposase and inactivated derivatives
M479_43	COG2888	peptidyl-tyrosine sulfation
M479_430	COG0560	Phosphoserine phosphatase
M479_4302	COG3177	Filamentation induced by cAMP protein fic
M479_4307	COG4886	Leucine-rich repeat (LRR) protein
M479_4309	COG3328	transposase activity
M479_431	COG0590	tRNA wobble adenosine to inosine editing
M479_4310	COG3328	transposase activity
M479_4313	COG0457	Tetratricopeptide repeat
M479_4317	COG4789	Type iii secretion
M479_4326	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M479_4327	COG4790	Type iii secretion
M479_4328	COG4794	Type iii secretion
M479_4329	COG4791	protein targeting
M479_4330	COG4792	protein secretion
M479_4332	COG2207	Transcriptional regulator
M479_438	COG2205	protein histidine kinase activity
M479_439	COG3170	Tfp pilus assembly protein FimV
M479_44	COG1126	abc transporter atp-binding protein
M479_440	COG2204	response regulator
M479_441	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M479_441	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M479_442	COG0347	Belongs to the P(II) protein family
M479_443	COG2188	Transcriptional regulator
M479_446	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M479_446	COG1017	nitric oxide dioxygenase activity
M479_449	COG3711	transcriptional antiterminator
M479_45	COG0765	amino acid transport
M479_450	COG2814	Major facilitator Superfamily
M479_451	COG3683	transport system, periplasmic component
M479_452	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
M479_453	COG0483	inositol monophosphate 1-phosphatase activity
M479_456	COG1104	cysteine desulfurase activity
M479_457	COG0822	iron-sulfur transferase activity
M479_46	COG0765	amino acid transport
M479_460	COG0443	Heat shock 70 kDa protein
M479_461	COG0633	Ferredoxin
M479_462	COG2975	iron-sulfur cluster assembly
M479_466	COG3468	outer membrane autotransporter barrel domain protein
M479_467	COG3468	outer membrane autotransporter barrel domain protein
M479_475	COG2976	Protein conserved in bacteria
M479_476	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M479_479	COG1645	bacterial-type flagellum-dependent swarming motility
M479_48	COG0815	Transfers the fatty acyl group on membrane lipoproteins
M479_481	COG0516	GMP reductase activity
M479_481	COG0517	IMP dehydrogenase activity
M479_483	COG1943	Transposase
M479_49	COG4535	Mg2 and Co2 transporter CorC
M479_490	COG3328	transposase activity
M479_493	COG0351	phosphomethylpyrimidine kinase
M479_498	COG3422	double-strand break repair
M479_499	COG0745	RESPONSE REGULATOR receiver
M479_500	COG2205	protein histidine kinase activity
M479_506	COG3842	ATPase activity
M479_508	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M479_51	COG1702	phosphate starvation-inducible protein PhoH
M479_510	COG1176	ABC-type spermidine putrescine transport system, permease component I
M479_511	COG1177	transmembrane transport
M479_512	COG0443	Heat shock 70 kDa protein
M479_513	COG2239	Acts as a magnesium transporter
M479_514	COG0248	Ppx GppA phosphatase
M479_515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M479_517	COG0581	inorganic phosphate transmembrane transporter activity
M479_521	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M479_522	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M479_525	COG1943	Transposase
M479_527	COG1393	Belongs to the ArsC family
M479_528	COG4783	chaperone-mediated protein folding
M479_529	COG0628	permease
M479_53	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M479_532	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M479_533	COG2716	regulation of RNA biosynthetic process
M479_535	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
M479_536	COG1943	Transposase
M479_538	COG2321	neutral zinc metallopeptidase
M479_542	COG1876	peptidase activity
M479_544	COG1393	Belongs to the ArsC family
M479_546	COG1840	ABC-type Fe3 transport system, periplasmic component
M479_547	COG1175	transmembrane transport
M479_548	COG3842	ATPase activity
M479_549	COG3119	arylsulfatase activity
M479_550	COG0641	radical SAM
M479_551	COG1988	membrane-bound metal-dependent
M479_553	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M479_555	COG2197	response regulator
M479_556	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M479_556	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
M479_557	COG3062	negative regulation of establishment of protein localization
M479_559	COG3043	anaerobic respiration
M479_560	COG3005	denitrification pathway
M479_569	COG3111	PFAM Bacterial OB fold (BOF) protein
M479_572	COG2837	iron assimilation
M479_573	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M479_575	COG4886	Leucine-rich repeat (LRR) protein
M479_577	COG2731	YhcH YjgK YiaL family protein
M479_578	COG1737	Transcriptional regulator
M479_580	COG4150	thiosulfate binding
M479_581	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M479_582	COG4208	sulfate ABC transporter
M479_583	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M479_586	COG0745	RESPONSE REGULATOR receiver
M479_587	COG5002	protein histidine kinase activity
M479_587	COG3850	Histidine kinase
M479_589	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M479_591	COG0006	proline dipeptidase activity
M479_593	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M479_596	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M479_597	COG0745	RESPONSE REGULATOR receiver
M479_598	COG2205	protein histidine kinase activity
M479_60	COG0367	asparagine synthase
M479_601	COG2190	(PTS) system
M479_603	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M479_604	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M479_605	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
M479_608	COG3530	Putative quorum-sensing-regulated virulence factor
M479_61	COG0647	UMP catabolic process
M479_611	COG1943	Transposase
M479_618	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M479_62	COG1846	Transcriptional regulator
M479_62	COG1940	carbohydrate kinase activity
M479_621	COG0667	Aldo Keto reductase
M479_626	COG0436	Aminotransferase
M479_627	COG3038	cytochrome b561
M479_63	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M479_633	COG3381	protein complex oligomerization
M479_634	COG3302	dmso reductase anchor subunit
M479_635	COG0437	4 iron, 4 sulfur cluster binding
M479_636	COG0243	molybdopterin cofactor binding
M479_643	COG2951	lytic endotransglycosylase activity
M479_65	COG1263	PTS System
M479_65	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M479_65	COG2190	(PTS) system
M479_655	COG3121	Chaperone
M479_656	COG3188	usher protein
M479_657	COG3328	transposase activity
M479_658	COG3188	usher protein
M479_671	COG3501	Rhs element vgr protein
M479_677	COG2824	Alkylphosphonate utilization operon protein PhnA
M479_679	COG1704	LemA family
M479_683	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M479_684	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M479_685	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M479_687	COG1138	Cytochrome C-type biogenesis protein
M479_688	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M479_689	COG4235	cytochrome complex assembly
M479_689	COG3088	subunit of a heme lyase
M479_690	COG4235	cytochrome complex assembly
M479_690	COG3088	subunit of a heme lyase
M479_693	COG3691	Protein conserved in bacteria
M479_696	COG2062	phosphohistidine phosphatase, SixA
M479_698	COG2890	protein-(glutamine-N5) methyltransferase activity
M479_70	COG0735	belongs to the Fur family
M479_701	COG0730	response to heat
M479_702	COG3101	peptidyl-lysine hydroxylation
M479_705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M479_706	COG1794	racemase activity, acting on amino acids and derivatives
M479_709	COG0697	spore germination
M479_712	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M479_714	COG0586	Pfam SNARE associated Golgi protein
M479_716	COG0285	dihydrofolate synthase activity
M479_717	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
M479_718	COG1286	toxin biosynthetic process
M479_719	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M479_720	COG0163	prenyltransferase activity
M479_721	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M479_722	COG4215	(ABC) transporter
M479_723	COG4160	amino acid transport
M479_724	COG4598	ABC transporter
M479_725	COG1090	epimerase
M479_727	COG0622	Phosphoesterase
M479_728	COG0622	Phosphoesterase
M479_729	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
M479_730	COG3037	sugar-specific permease SgaT UlaA
M479_733	COG1609	Transcriptional regulator
M479_734	COG0857	belongs to the CobB CobQ family
M479_734	COG0280	phosphate acetyltransferase
M479_738	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M479_739	COG0471	metal ion transport
M479_739	COG0490	domain, Protein
M479_74	COG0596	Alpha beta hydrolase
M479_741	COG0436	Aminotransferase
M479_742	COG0583	DNA-binding transcription factor activity
M479_744	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M479_746	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
M479_748	COG1034	ATP synthesis coupled electron transport
M479_751	COG0839	Belongs to the complex I subunit 6 family
M479_753	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M479_754	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M479_757	COG2731	YhcH YjgK YiaL family protein
M479_758	COG3265	gluconokinase activity
M479_759	COG1028	Short-chain dehydrogenase reductase Sdr
M479_76	COG2963	transposase activity
M479_761	COG1609	Transcriptional regulator
M479_762	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M479_765	COG0129	dihydroxy-acid dehydratase activity
M479_767	COG4575	ribosome binding
M479_769	COG1169	isochorismate synthase
M479_77	COG0582	viral genome integration into host DNA
M479_772	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M479_775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M479_779	COG1126	abc transporter atp-binding protein
M479_780	COG0765	amino acid transport
M479_781	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M479_787	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M479_791	COG1063	alcohol dehydrogenase
M479_792	COG1879	ABC-type sugar transport system periplasmic component
M479_794	COG1129	ABC transporter
M479_795	COG1172	Belongs to the binding-protein-dependent transport system permease family
M479_796	COG1609	Transcriptional regulator
M479_797	COG0583	DNA-binding transcription factor activity
M479_798	COG0473	3-isopropylmalate dehydrogenase activity
M479_799	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M479_800	COG4638	Rieske (2fe-2S)
M479_801	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M479_802	COG2831	hemolysin activation secretion protein
M479_803	COG3210	domain, Protein
M479_806	COG3210	domain, Protein
M479_81	COG3657	addiction module killer protein
M479_810	COG3210	domain, Protein
M479_812	COG3328	transposase activity
M479_813	COG3842	ATPase activity
M479_815	COG1609	Transcriptional regulator
M479_818	COG0395	ABC-type sugar transport system, permease component
M479_819	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
M479_823	COG0668	transmembrane transport
M479_824	COG1518	maintenance of DNA repeat elements
M479_825	COG1203	CRISPR-associated helicase, Cas3
M479_830	COG0667	Aldo Keto reductase
M479_832	COG0477	Major facilitator Superfamily
M479_834	COG0583	DNA-binding transcription factor activity
M479_835	COG3916	Acyl-homoserine-lactone synthase
M479_836	COG2771	luxR family
M479_840	COG0628	permease
M479_844	COG3328	transposase activity
M479_847	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M479_848	COG1530	ribonuclease E activity
M479_849	COG0564	pseudouridine synthase activity
M479_851	COG1399	metal-binding, possibly nucleic acid-binding protein
M479_852	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M479_856	COG1028	Short-chain dehydrogenase reductase Sdr
M479_858	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M479_859	COG1943	Transposase
M479_860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M479_861	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M479_863	COG0470	DNA polymerase III
M479_864	COG0084	hydrolase, TatD family'
M479_865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M479_865	COG1263	PTS System
M479_867	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M479_868	COG0537	adenosine 5'-monophosphoramidase activity
M479_869	COG5633	Lipoprotein
M479_872	COG1472	Belongs to the glycosyl hydrolase 3 family
M479_874	COG1252	NADH dehydrogenase
M479_877	COG3328	transposase activity
M479_878	COG3134	Outer membrane lipoprotein
M479_879	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M479_880	COG4591	ABC-type transport system involved in lipoprotein release permease component
M479_882	COG4591	ABC-type transport system involved in lipoprotein release permease component
M479_884	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M479_886	COG2850	peptidyl-arginine hydroxylation
M479_888	COG0745	RESPONSE REGULATOR receiver
M479_890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M479_894	COG1187	pseudouridine synthase activity
M479_895	COG0538	isocitrate dehydrogenase activity
M479_898	COG0840	transmembrane signaling receptor activity
M479_899	COG0702	epimerase
M479_9	COG3962	Belongs to the TPP enzyme family
M479_900	COG1733	regulation of RNA biosynthetic process
M479_905	COG1522	sequence-specific DNA binding
M479_908	COG3321	synthase
M479_908	COG0604	alcohol dehydrogenase
M479_908	COG1028	Short-chain dehydrogenase reductase Sdr
M479_91	COG0582	viral genome integration into host DNA
M479_910	COG1278	Cold shock
M479_912	COG0840	transmembrane signaling receptor activity
M479_913	COG0840	transmembrane signaling receptor activity
M479_914	COG3328	transposase activity
M479_915	COG1285	pathogenesis
M479_920	COG1360	Flagellar Motor Protein
M479_921	COG0643	Histidine kinase
M479_921	COG2198	Histidine kinase
M479_922	COG0835	chemotaxis
M479_923	COG2271	Major facilitator Superfamily
M479_924	COG0251	oxidation-reduction process
M479_926	COG2964	Protein conserved in bacteria
M479_930	COG0840	transmembrane signaling receptor activity
M479_931	COG0840	transmembrane signaling receptor activity
M479_932	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M479_934	COG0745	RESPONSE REGULATOR receiver
M479_935	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
M479_936	COG3023	N-Acetylmuramoyl-L-alanine amidase
M479_938	COG5295	Hep Hag repeat protein
M479_94	COG2867	negative regulation of translational initiation
M479_941	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M479_953	COG3121	Chaperone
M479_957	COG3008	intermembrane lipid transfer
M479_958	COG2995	paraquat-inducible protein a
M479_959	COG1956	GAF domain-containing protein
M479_96	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M479_961	COG0793	Belongs to the peptidase S41A family
M479_964	COG3539	Fimbrial protein
M479_965	COG3121	Chaperone
M479_968	COG3121	Chaperone
M479_969	COG2814	Major facilitator Superfamily
M479_97	COG0497	DNA recombination
M479_970	COG0823	Involved in the tonB-independent uptake of proteins
M479_972	COG3023	N-Acetylmuramoyl-L-alanine amidase
M479_974	COG1988	membrane-bound metal-dependent
M479_975	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M479_976	COG1653	transport
M479_977	COG3842	ATPase activity
M479_978	COG0395	ABC-type sugar transport system, permease component
M479_979	COG1175	transmembrane transport
M479_98	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M479_981	COG1028	Short-chain dehydrogenase reductase Sdr
M479_983	COG1917	Cupin 2, conserved barrel domain protein
M479_984	COG3328	transposase activity
M479_985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M479_988	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M479_989	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M479_990	COG1121	(ABC) transporter
M479_991	COG0803	Belongs to the bacterial solute-binding protein 9 family
M479_995	COG4249	Peptidase C14 caspase catalytic subunit p20