locus-tag class description M482_10 ENOG4105DDY UPF0142 protein ycaO M482_1000 ENOG4105W0E 50S ribosomal protein L33 M482_1003 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase M482_1008 ENOG4105DSJ YicC domain protein M482_1009 ENOG4105EN6 Membrane M482_101 ENOG4105E66 phosphoriboisomerase A M482_1010 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) M482_1012 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) M482_1013 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) M482_1014 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase M482_1015 ENOG4105CB5 ATP-dependent DNA helicase recG M482_1016 ENOG4105D6U Sodium Glutamate Symporter M482_1017 ENOG4105C2W permease M482_1018 ENOG4105JV1 AsmA family M482_1019 ENOG4105SUU thioesterase domain M482_1023 ENOG4107S2Z UPF0761 membrane protein M482_1024 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 M482_1026 ENOG4105C5F glutamine synthetase M482_1027 ENOG4105CUX Signal transduction histidine kinase M482_1028 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family M482_1029 ENOG4105D4P Coproporphyrinogen iii oxidase M482_103 ENOG4105C26 Dehydrogenase M482_1032 ENOG4105C2M dna polymerase I M482_1033 ENOG4108Z33 Thiol disulfide Interchange Protein M482_1034 ENOG4105E27 serine threonine protein kinase M482_1035 ENOG4105PC1 Conserved Protein M482_1037 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b M482_1043 ENOG4107EJG GntR family transcriptional regulator M482_1045 ENOG4105C0R drug resistance transporter emrb qaca subfamily M482_1046 ENOG4108RVA ribokinase M482_1047 ENOG4108RVA ribokinase M482_1053 ENOG4108VVK transcriptional Regulator, AsnC M482_1054 ENOG4105QTB Flavodoxin M482_1057 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation M482_1059 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) M482_106 ENOG4105CHR reductase M482_1067 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) M482_1069 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) M482_107 ENOG4105KRS Proteinase inhibitor M482_1070 ENOG4105C8U phosphate abc transporter M482_1071 ENOG4105E2Z phosphate ABC transporter (Permease M482_1075 ENOG4106PMH Extracellular solute-binding protein family 3 M482_1076 ENOG4105EAD ABC transporter M482_1077 ENOG4105DRP amino acid AbC transporter M482_1078 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 M482_1079 ENOG4105C7N Xanthine uracil vitamin C permease M482_1084 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins M482_1087 ENOG4105VG0 50S ribosomal protein l34 M482_1090 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) M482_1091 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) M482_1092 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M482_1093 ENOG410667J hydrolase M482_1094 ENOG4105DQ6 Transposase M482_1097 ENOG4105C7B Threonine dehydratase M482_1098 ENOG4105D99 atp gtp-binding protein M482_1099 ENOG4105D99 atp gtp-binding protein M482_11 ENOG4105TMB Formate nitrite transporter M482_110 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) M482_1100 ENOG4105R2A (LipO)protein M482_1104 ENOG4105JKW Valine--pyruvate aminotransferase M482_1106 ENOG4107T9C Alpha amylase catalytic region M482_1109 ENOG4108ZG0 Ompa motb domain protein M482_111 ENOG4105DEI Mannitol dehydrogenase M482_1111 ENOG4108R3E Dna-3-methyladenine glycosylase i M482_1115 ENOG4106JH6 (LipO)protein M482_1116 ENOG4105CTS PTS system mannitol-specific M482_1118 ENOG4105E61 Mannitol repressor protein M482_112 ENOG4107YCY Transcriptional regulator M482_1120 ENOG4108YYI Protein of unknown function (DUF2810) M482_1124 ENOG4105C8Q Methyl-accepting chemotaxis M482_1125 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) M482_1127 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) M482_1128 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) M482_1129 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein M482_1130 ENOG4108MG3 formate dehydrogenase M482_1133 ENOG4105EM7 Selenocysteine-specific translation elongation factor M482_1134 ENOG4105D13 transposase M482_114 ENOG4105CKI cobalamin synthesis protein M482_1140 ENOG4105DQ6 Transposase M482_1142 ENOG4105E98 transcriptional regulator DeoR family M482_1146 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) M482_1147 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) M482_1149 ENOG4105MJ2 Competence protein M482_115 ENOG41076MN Phosphoesterase, PA-phosphatase related M482_1151 ENOG4105RID UPF0379 protein yhcN M482_1153 ENOG4105CE1 Ferrous iron transport protein b M482_1154 ENOG4105XFK Ferrous iron transport protein A M482_1155 ENOG4105BZM domain protein M482_1156 ENOG4108RRZ Transcription elongation factor GreB M482_1157 ENOG4105DPZ Two component transcriptional regulator (Winged helix family M482_1158 ENOG4105E0F Histidine kinase M482_116 ENOG4107TT5 NLP P60 protein M482_1161 ENOG4105VEJ Heat shock protein M482_1162 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 M482_1163 ENOG4105DQY intracellular growth attenuator M482_1165 ENOG4107RK2 ADP-ribose diphosphatase NudE M482_1166 ENOG4108JQC penicillin-binding protein 1A M482_1171 ENOG4105E4G Type IV pilus M482_1176 ENOG4105DJV ribulose-phosphate 3-epimerase M482_1177 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) M482_1178 ENOG4105C31 Tryptophanyl-tRNA synthetase M482_118 ENOG4105CXC rtn protein M482_1180 ENOG4107V9H nitrite transporter M482_1181 ENOG4105WZK nitrite reductase NADPH small subunit M482_1182 ENOG4107QZF nitrite reductase NADPH large subunit M482_1183 ENOG4105DZC cytosine deaminase M482_1186 ENOG41060NJ transcriptional regulator M482_1187 ENOG4105F8D glycoside hydrolase family 4 M482_1188 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) M482_1189 ENOG4105D7A ATP-binding protein M482_119 ENOG4105E43 Extracellular solute-binding protein, family 5 M482_1191 ENOG4105C8Y Acetylornithine aminotransferase M482_1192 ENOG410613R integral membrane protein, YccS YhfK family M482_1194 ENOG4108UKZ OsmC family M482_1196 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) M482_1198 ENOG4105DNZ Alpha Beta Hydrolase M482_12 ENOG4105C6N Formate acetyltransferase M482_120 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component M482_1200 ENOG4106FTQ Taurine ABC transporter, periplasmic M482_1202 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component M482_1203 ENOG4105E2B Taurine dioxygenase M482_1206 ENOG4105K64 Glycosyl transferase, family 2 M482_1207 ENOG4105C5H ABC transporter M482_121 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component M482_1210 ENOG4105VKU nucleicacid-binding protein M482_1211 ENOG4108YZY peptidylprolyl cis-trans isomerase M482_1213 ENOG4108V1T peptidylprolyl cis-trans isomerase M482_1214 ENOG4105WWK YheO domain protein M482_1219 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) M482_122 ENOG4108JQ5 ABC transporter M482_1222 ENOG4108RS6 transposase M482_123 ENOG4105HG6 M482_1230 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) M482_1232 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) M482_1233 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) M482_1235 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal M482_124 ENOG4105C2C drug resistance transporter, Bcr CflA M482_1244 ENOG4105VPB 50S ribosomal protein L30 M482_1246 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) M482_1247 ENOG41067V7 50S ribosomal protein L36 M482_125 ENOG4105I08 Pseudouridine synthase M482_1250 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) M482_1253 ENOG4105W1Y Transcriptional regulator M482_1254 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system M482_1256 ENOG4105C1A potassium transporter peripheral membrane M482_126 ENOG4105CFI type iii restriction protein res subunit M482_1260 ENOG4105C79 DNA protecting protein DprA M482_1262 ENOG4108WI1 Dna topoisomerase M482_1265 ENOG4108Z0R Transferase M482_1272 ENOG4105CMM transposase M482_1279 ENOG41062QD Membrane M482_128 ENOG4108RS6 transposase M482_1281 ENOG4105CK2 sodium dicarboxylate symporter M482_1282 ENOG4105WH1 Two component transcriptional regulator luxr family M482_1283 ENOG4105BZU Histidine kinase M482_1295 ENOG4108JIR Flagellum-specific ATP synthase M482_1298 ENOG41063Q7 Type III secretion system protein M482_1299 ENOG4108HHI Type III secretion system protein M482_130 ENOG4105PAN UPF0352 protein M482_1300 ENOG41083GP type iii secretion M482_1301 ENOG4108TN6 type iii secretion M482_1302 ENOG4108IUF type iii secretion M482_1303 ENOG41066VF YeeE YedE family protein M482_1304 ENOG4105KSU Redox protein M482_1305 ENOG4105EQ2 LysR family Transcriptional regulator M482_1306 ENOG4105C44 Serine transporter M482_1307 ENOG4105C28 cystathionine M482_1309 ENOG4105EHG Permease protein M482_131 ENOG4105E68 Sulfatase M482_1310 ENOG4107R4I Periplasmic binding protein M482_1311 ENOG4106QJH hemin transport protein M482_1312 ENOG4107ENK receptor M482_1313 ENOG4107F3C Hemin uptake protein M482_1315 ENOG41090JE Utilization Protein M482_1316 ENOG4105D4P Coproporphyrinogen iii oxidase M482_1320 ENOG4105DAX Pfam:DUF2983 M482_1332 ENOG4108S1B Periplasmic chaperone protein M482_134 ENOG4105GMB type VI secretion system effector, hcp1 family M482_1341 ENOG41080IJ Diacylglycerol kinase M482_1343 ENOG4105MYN Zinc uptake regulation protein M482_1344 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) M482_1345 ENOG4105P4Z Phage shock protein G M482_1346 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein M482_1347 ENOG4105CDU Replicative dna helicase M482_1348 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) M482_1349 ENOG4105CGF Aromatic amino acid aminotransferase M482_1350 ENOG4105MSB protein, conserved in bacteria M482_1351 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) M482_1352 ENOG4108UUM single-stranded DNA-binding protein M482_1354 ENOG4105C0A alcohol dehydrogenase M482_1368 ENOG4108SIC Transcriptional regulator M482_1369 ENOG4105BZ8 glutamate synthase M482_1370 ENOG4108RC0 Electron transport protein M482_1371 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) M482_1374 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter M482_1379 ENOG4108ZVF (LipO)protein M482_138 ENOG4105CS2 ec 3.2.1.21 M482_1380 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein M482_1382 ENOG4105KPY Small multidrug resistance protein M482_1383 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) M482_1388 ENOG4105EGS Mechanosensitive ion channel M482_1391 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) M482_1394 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) M482_1395 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) M482_1396 ENOG4105K8N protein family UPF0079, ATPase M482_1397 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase M482_14 ENOG4105F1A Pyruvate formate-lyase M482_140 ENOG4108Q3X Transcriptional regulator M482_1401 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) M482_1402 ENOG4107QJR hflk protein M482_1403 ENOG4105EPW hflc protein M482_1407 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) M482_1408 ENOG4105C2N RNA methyltransferase TrmH family group 3 M482_1409 ENOG4105CSU acyl-Coa dehydrogenase M482_1410 ENOG4105WSB biofilm stress and motility protein A M482_1413 ENOG4105DIJ Phosphoethanolamine transferase M482_1414 ENOG4108KX4 response regulator M482_1415 ENOG4105BZU Histidine kinase M482_1416 ENOG4105CXY transporter M482_1420 ENOG4105D5K Hemolysin activator protein M482_1422 ENOG4105DEF Extracellular solute-binding protein, family 5 M482_1423 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component M482_1424 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component M482_1425 ENOG4105C3U ABC transporter M482_1426 ENOG4108JQ7 (ABC) transporter M482_1427 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) M482_1428 ENOG4105BZU Histidine kinase M482_1429 ENOG4108PU9 oligogalacturonate-specific porin M482_1434 ENOG4105CS0 peptidase M482_1435 ENOG4107SS6 2-dehydro-3-deoxygluconokinase M482_1436 ENOG4105VSH 4-oxalocrotonate tautomerase M482_1437 ENOG4105CMB EAL domain-containing protein M482_1438 ENOG41066T0 asmA family M482_1439 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) M482_144 ENOG4108T86 baseplate J family protein M482_1440 ENOG4107H3J ribonuclease M482_1445 ENOG4105BZW Glycerate kinase M482_1446 ENOG4107QQ0 gntp family M482_1447 ENOG4107VHA regulatoR M482_1448 ENOG4105DC8 reductase M482_1449 ENOG4105D6S protein involved in catabolism of external DNA M482_1450 ENOG4105DGW oligopeptidase A M482_1454 ENOG4108M6U Universal stress protein A M482_1457 ENOG4105CJ3 phosphate transporter M482_1458 ENOG4105CBX hi0933 family M482_1461 ENOG4108RS6 transposase M482_1463 ENOG4105CNN ABC, transporter M482_1464 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator M482_1466 ENOG4105D2N Aldolase M482_1468 ENOG4105DPZ Two component transcriptional regulator (Winged helix family M482_1470 ENOG4105C2I pirin domain protein M482_1471 ENOG4105DIQ Transcriptional regulator M482_1472 ENOG4105DIQ Transcriptional regulator M482_1473 ENOG4105C6Z Gluconate M482_1474 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family M482_1478 ENOG41076UM multiple antibiotic resistance (MarC)-related protein M482_1479 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) M482_1485 ENOG4108HRK Histidine kinase M482_1490 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) M482_1491 ENOG4105C6V Glycerol-3-phosphate dehydrogenase M482_1494 ENOG4105DQ6 Transposase M482_1498 ENOG4105C1J atp-dependent rna helicase M482_15 ENOG4108ISG Major Facilitator M482_1501 ENOG4105DEN Luciferase family M482_1504 ENOG4105BZS acriflavin resistance protein M482_1505 ENOG4105ENJ RND efflux system, outer membrane lipoprotein M482_1506 ENOG4106RZ4 Peptidase U32 M482_1507 ENOG4105CFP Peptidase U32 M482_1508 ENOG4105XPQ lipid carrier protein M482_1509 ENOG4108YYD acetyltransferase M482_1514 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component M482_1515 ENOG4105DRS transport system, permease M482_1519 ENOG4105K4T epimerase M482_1520 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein M482_1521 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) M482_1522 ENOG4105FD8 phosphonate metabolism protein PhnM M482_1523 ENOG4105HRV phosphonate c-p lyase system protein phnl M482_1524 ENOG4105ENV phosphonate C-P lyase system protein PhnK M482_1525 ENOG4105FT8 Phosphonate metabolism M482_1526 ENOG4105EKV Phosphonate metabolism protein M482_1527 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH M482_1528 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG M482_1529 ENOG4107RJJ Transcriptional regulator M482_153 ENOG4105TKZ Tail Sheath M482_1531 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) M482_1532 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase M482_1533 ENOG4108JQ7 (ABC) transporter M482_1534 ENOG4105C3U ABC transporter M482_1535 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component M482_1536 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component M482_1539 ENOG4105XEP YhcH YjgK YiaL family protein M482_1540 ENOG4105DBV ornithine carbamoyltransferase M482_1541 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) M482_1542 ENOG4108MJ3 acetyltransferase M482_1543 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) M482_1544 ENOG4105MYG DNA polymerase iii, chi subunit M482_1546 ENOG4108M8S permease YjgP YjgQ family protein M482_1547 ENOG4108K5H permease YjgP YjgQ family protein M482_1551 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) M482_1554 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 M482_1566 ENOG4108M3P Membrane M482_1568 ENOG4108XCZ PTS System M482_1569 ENOG4106R3P AraC family transcriptional regulator M482_157 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) M482_1570 ENOG4108YRF PTS System M482_1571 ENOG4105DM4 PTS System M482_1572 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) M482_1573 ENOG4105RI1 glycoprotein receptor M482_158 ENOG4105MVE transcriptional regulator M482_1580 ENOG4105DKT Transcriptional regulator M482_1582 ENOG4105DKP glycosyl transferase, family 9 M482_1585 ENOG410624X efflux transporter, rnd family, mfp subunit M482_1586 ENOG4105BZS acriflavin resistance protein M482_1589 ENOG4105BZU Histidine kinase M482_1590 ENOG4105YBH Protein of unknown function (DUF1435) M482_1593 ENOG4108WPU DNA polymerase III subunit psi M482_1594 ENOG4105KEG ribosomal-protein-alanine acetyltransferase M482_1596 ENOG4105K3G Periplasmic Protein M482_1598 ENOG4108NRW Phospholipase, patatin family M482_1599 ENOG4105EYA deoxyribonuclease M482_160 ENOG4105G63 Type III effector Hrp-dependent M482_1600 ENOG4105D9N nucleoside M482_1601 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) M482_1605 ENOG41062Z9 Membrane M482_1606 ENOG4105EAC phosphoserine phosphatase M482_1607 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) M482_1608 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase M482_161 ENOG4105HRS Antitermination protein M482_1611 ENOG4105C5H ABC transporter M482_1612 ENOG41090EK ompa motb domain protein M482_1613 ENOG4108KHX Diguanylate cyclase M482_1616 ENOG4107SC1 transglycosylase M482_1618 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) M482_1619 ENOG4105UEI Transcriptional Regulator AraC Family M482_1622 ENOG4108RH0 Crea protein M482_1623 ENOG41065U4 response regulator M482_163 ENOG4105Y50 Virulence Protein M482_1631 ENOG4108RIR Molybdenum cofactor biosynthesis protein M482_1634 ENOG4106HK8 GPR1 FUN34 yaaH family protein M482_1638 ENOG41063Z6 transcriptional regulator, lysR family M482_1640 ENOG4105DTN riboflavin biosynthesis protein ribF M482_1643 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase M482_1646 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain M482_1647 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain M482_1648 ENOG4105N14 lysine exporter protein LysE YggA M482_1649 ENOG4105DWK Membrane M482_1651 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) M482_1656 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) M482_1657 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) M482_1659 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) M482_166 ENOG4105C8Q Methyl-accepting chemotaxis M482_1660 ENOG4105D3G Pseudouridine synthase M482_1669 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M482_1670 ENOG4105CS6 Rhs element vgr protein M482_168 ENOG4105CT4 transporter M482_1681 ENOG4105CQ2 DNA polymerase M482_1682 ENOG4108KF1 Membrane M482_1684 ENOG4106SMU thiamine transporter membrane protein M482_1685 ENOG4105DP9 ABC transporter M482_1688 ENOG4105S8Q sugar efflux transporter M482_169 ENOG4107R6D beta-lactam binding protein AmpH M482_1691 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) M482_1694 ENOG41064T2 transcriptional regulator, lysR family M482_1695 ENOG4108IQE Amp-dependent synthetase and ligase M482_1697 ENOG4105C7K acetolactate synthase M482_1698 ENOG4108ZP8 Acetolactate synthase small subunit M482_1699 ENOG4108RS6 transposase M482_17 ENOG4105D1H recombination factor protein RarA M482_1700 ENOG4107B7Y DNA-binding transcriptional regulator FruR M482_1702 ENOG4108RNS Exports L-alanine (By similarity) M482_1705 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) M482_1706 ENOG4105CJN penicillin-binding protein M482_1707 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) M482_1708 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) M482_1711 ENOG4105CNI cell division protein FtsW M482_1715 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) M482_1716 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) M482_1717 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) M482_172 ENOG4105FCK Membrane M482_1722 ENOG4105M6F mutator MutT protein M482_1728 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) M482_1730 ENOG4105D7Q type ii secretion system M482_1731 ENOG4107QHF type ii secretion system protein e M482_1732 ENOG4108ZUW Major pilin subunit M482_1733 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase M482_1734 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase M482_1735 ENOG4106A72 regulatory protein AmpE M482_1736 ENOG4105C85 amino acid M482_1737 ENOG41073TP transcriptional regulator M482_1738 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) M482_1739 ENOG4107QSN dihydrolipoamide acetyltransferase M482_174 ENOG4106UW1 Major Facilitator superfamily M482_1740 ENOG4107QN2 dihydrolipoyl dehydrogenase M482_1741 ENOG4108RS6 transposase M482_1742 ENOG4107QIJ Aconitate hydratase 2 M482_1744 ENOG4105RPH Inner membrane protein YddG M482_1747 ENOG4108ZRK uncharacterized protein yacC M482_1748 ENOG4105E3B Multicopper oxidase M482_1749 ENOG4108UGV hypoxanthine phosphoribosyltransferase M482_175 ENOG4106UW1 Major Facilitator superfamily M482_1750 ENOG41077A9 carbonic anhydrase M482_1751 ENOG4105DA5 (ABC) transporter M482_1752 ENOG4105E3A (ABC) transporter M482_1754 ENOG4107BJW polysaccharide deacetylase M482_1758 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase M482_1759 ENOG4105DJ0 Poly(A) Polymerase M482_176 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC M482_1760 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) M482_1761 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters M482_1763 ENOG4107XID 2'-5' rna ligase M482_1764 ENOG4105CQ7 ATP-dependent helicase M482_1765 ENOG4105BZ4 penicillin-binding protein M482_1766 ENOG4105E0A ABC, transporter M482_1767 ENOG4105J76 Periplasmic binding protein M482_1768 ENOG4105S6R Iron-hydroxamate transporter permease subunit M482_177 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC M482_1772 ENOG4105EN6 Membrane M482_1774 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) M482_1776 ENOG4105C0H protease M482_1777 ENOG4105BZU Histidine kinase M482_1778 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) M482_1779 ENOG4105DXN mazG family M482_178 ENOG41068CG regulatoR M482_1783 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) M482_1784 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase M482_179 ENOG4105BZU Histidine kinase M482_1795 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) M482_1796 ENOG4105N0Z inner membrane protein ygbE M482_1798 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) M482_180 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M482_1803 ENOG4108K5P (LipO)protein M482_1804 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) M482_1805 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) M482_1806 ENOG4108YZG isomerase M482_1807 ENOG4105CPQ Dehydrogenase M482_1808 ENOG4105CHR reductase M482_1809 ENOG4105CMT Dihydroxyacetone kinase M482_1811 ENOG4105DKT Transcriptional regulator M482_1816 ENOG4105E89 ABC transporter M482_1817 ENOG4105CA0 peroxidase M482_1819 ENOG4105D05 Receptor M482_182 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) M482_1821 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) M482_1823 ENOG4107GFK fumarate M482_1824 ENOG4105CMG Carbohydrate kinase M482_1825 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase M482_1826 ENOG4105F5R ABC transporter M482_1827 ENOG4105CNN ABC, transporter M482_1828 ENOG4105C2J ABC transporter M482_183 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) M482_1830 ENOG4105E98 transcriptional regulator DeoR family M482_1831 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase M482_1832 ENOG4107QY8 reductase M482_1833 ENOG4105QAX Iron-sulfur M482_1834 ENOG4107KGK dmso reductase anchor subunit M482_1835 ENOG4108NEM leader-binding protein dmsD M482_1836 ENOG4105CPW cytochrome b561 M482_1837 ENOG4108XVM Cytochrome b(562) M482_184 ENOG4105XPH Ferredoxin M482_1841 ENOG4105C2J ABC transporter M482_1842 ENOG4105CNN ABC, transporter M482_1843 ENOG4108HHA Transketolase M482_1844 ENOG4108IUS Transketolase M482_1845 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) M482_1852 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) M482_1853 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) M482_1857 ENOG4107VXZ Hydrolase M482_1858 ENOG4105W39 Membrane M482_1859 ENOG4105D9M gamma-glutamylcysteine synthetase M482_1861 ENOG4108JU6 CBS domain protein M482_1862 ENOG4106KVJ cytochrome C assembly protein M482_1863 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY M482_1868 ENOG4108NE3 Salt-induced outer membrane protein M482_1869 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter M482_187 ENOG4105E0U tyrosine-specific transport protein M482_1870 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter M482_1871 ENOG4108NEV two component transcriptional regulator, LytTR family M482_1872 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) M482_1876 ENOG4105EHE chorismate mutase- prephenate dehydrogenase M482_1879 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA M482_188 ENOG4108UII YfaZ family M482_1880 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane M482_1881 ENOG4105C34 Pseudouridine synthase M482_1882 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase M482_1883 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M482_189 ENOG4105CH6 catalase M482_1894 ENOG4107QP3 malate synthase g M482_1895 ENOG4108I9X Isocitrate lyase M482_1897 ENOG41069M3 Transcriptional regulator M482_1898 ENOG4105C3R Methionine synthase M482_190 ENOG4105DVT helicase M482_1902 ENOG4105CFH Aspartokinase M482_1905 ENOG4105EG2 ABC transporter, permease M482_1906 ENOG4105D56 permease protein M482_1907 ENOG4107FKK extracellular solute-binding protein family 1 M482_1911 ENOG4107W52 maltose operon periplasmic protein M482_1913 ENOG4108WC9 type VI secretion system effector, hcp1 family M482_1917 ENOG4105DQ6 Transposase M482_192 ENOG4105FDR Membrane M482_1926 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M482_1933 ENOG4105CS6 Rhs element vgr protein M482_1936 ENOG4105CNA YD repeat protein M482_194 ENOG4105CXN decarboxylase M482_1942 ENOG4105CS6 Rhs element vgr protein M482_1944 ENOG4105CNA YD repeat protein M482_1947 ENOG4107TYG Oxidoreductase domain-containing protein M482_1948 ENOG4105W4W Transcriptional regulator M482_1949 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) M482_1950 ENOG4108RVA ribokinase M482_1951 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) M482_1953 ENOG4105GVF (ABC) transporter M482_1955 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component M482_1958 ENOG4105C7N Xanthine uracil vitamin C permease M482_1959 ENOG4105EEQ Na H antiporter M482_196 ENOG4105CXN decarboxylase M482_1961 ENOG4105D1S lipid A biosynthesis M482_1963 ENOG4105C2J ABC transporter M482_1964 ENOG4105CNN ABC, transporter M482_1966 ENOG4105EF1 ribulokinase M482_1967 ENOG4105C2X Arabinose 5-phosphate isomerase M482_1968 ENOG4105CYM Glutathione S-transferase M482_197 ENOG4105D5Q Arginine ornithine antiporter M482_1971 ENOG4108RS6 transposase M482_1972 ENOG4105VEQ Cold shock protein M482_1973 ENOG4105VEQ Cold shock protein M482_1974 ENOG4108XTF Outer Membrane Lipoprotein M482_1977 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase M482_1978 ENOG4105CSH Transporter M482_198 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component M482_1981 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) M482_1982 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) M482_1984 ENOG4108IA2 Sodium pantothenate symporter M482_1985 ENOG4105RG0 Membrane M482_1987 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase M482_1988 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein M482_199 ENOG4108IJ8 ABC transporter M482_1991 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) M482_1992 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family M482_1993 ENOG41062P1 Diguanylate cyclase phosphodiesterase M482_1994 ENOG4105DFF Rod shape-determining protein mreb M482_1995 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) M482_1996 ENOG4105VQ7 Rod shape-determining protein MreD M482_1998 ENOG4105C03 ribonuclease M482_1999 ENOG4105QD6 exported protein M482_20 ENOG4105CNU cell division protein FtsK M482_200 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component M482_2001 ENOG4105D1U peptidase U62 modulator of DNA gyrase M482_201 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system M482_2011 ENOG4105CR8 Transcriptional regulator M482_2015 ENOG4105C26 Dehydrogenase M482_2018 ENOG4105UNR (Barnase) inhibitor M482_202 ENOG4105KHC sulfurtransferase M482_2020 ENOG4105CMS peptidase U62, modulator of DNA gyrase M482_2022 ENOG4108XVM Cytochrome b(562) M482_2023 ENOG4105NXH GreA GreB family elongation factor M482_2024 ENOG4105CG3 alpha amylase, catalytic region M482_2025 ENOG4105C5Y PTS System M482_2026 ENOG4105D4X repressor M482_2028 ENOG4105KME endoribonuclease L-psp M482_2031 ENOG41080Z8 PHOSPHOCARRIER protein M482_2033 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN M482_2034 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA M482_2035 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) M482_2036 ENOG4108IUZ ABC transporter M482_2037 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA M482_2038 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) M482_2039 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase M482_2040 ENOG4105C2X Arabinose 5-phosphate isomerase M482_2041 ENOG4105FEU K -dependent Na -Ca exchanger M482_2042 ENOG4105DHJ ABC, transporter M482_2043 ENOG4105CY3 ABC transporter, permease M482_2044 ENOG4107PE3 Mammalian cell entry related domain protein M482_2045 ENOG4105E3I toluene tolerance M482_2046 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane M482_2047 ENOG4105VFK BolA family M482_2049 ENOG4105C0H protease M482_205 ENOG4108IV0 ABC, transporter M482_2050 ENOG4108RS6 transposase M482_2051 ENOG4105C0H protease M482_2052 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III M482_2053 ENOG4105D6Z AFG1 family ATPase M482_2056 ENOG4107MKT Stringent starvation protein a M482_2057 ENOG4105KB2 stringent starvation protein b M482_2059 ENOG4105BZ8 glutamate synthase M482_206 ENOG4108JJB ABC transporter M482_2060 ENOG4105CBC glutamate synthase M482_2061 ENOG4105N5T Radical SAM Protein M482_2062 ENOG4105BZU Histidine kinase M482_2063 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain M482_2065 ENOG4105W4M Transport-associated protein M482_2069 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) M482_207 ENOG4105CNN ABC, transporter M482_2070 ENOG4108CNN domain protein M482_2071 ENOG4105CWB LysR family transcriptional Regulator M482_2072 ENOG4105CHF Glutathione S-transferase M482_2073 ENOG4108VBZ doxx family M482_2075 ENOG41090KG Inner membrane protein YqjE M482_2076 ENOG4105NE1 Conserved Protein M482_2079 ENOG4106W5V Membrane M482_208 ENOG4105C32 Amino acid ABC transporter (Permease) M482_2082 ENOG4105DPW Major facilitator superfamily MFS_1 M482_2083 ENOG4105DPW Major facilitator superfamily MFS_1 M482_2085 ENOG4107QZW Altronate oxidoreductase M482_2086 ENOG4105CTX dehydratase M482_2087 ENOG4105P66 Membrane M482_2088 ENOG4108RS6 transposase M482_2090 ENOG4105EE0 oxidoreductase M482_2091 ENOG4108VKG metal-dependent hydrolase M482_2094 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase M482_2095 ENOG4108YK4 Acid-resistance membrane protein M482_2098 ENOG4108M24 von Willebrand factor, type A M482_21 ENOG4105EW9 transcriptional regulator AsnC family M482_210 ENOG4108W15 Protein of unknown function (DUF1456) M482_2101 ENOG4108M24 von Willebrand factor, type A M482_2102 ENOG4105D5K Hemolysin activator protein M482_2103 ENOG4105CKT filamentous hemagglutinin M482_2105 ENOG4105CKT filamentous hemagglutinin M482_2107 ENOG4105CKT filamentous hemagglutinin M482_2112 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 M482_2113 ENOG4107KJX Transcriptional regulator M482_2114 ENOG4108IJG ABC transporter substrate-binding protein M482_2116 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component M482_2118 ENOG4107QK4 glycoside hydrolase, family 3 domain protein M482_2120 ENOG4108MI0 Resistance protein M482_2121 ENOG4105J12 Multidrug resistance protein mdtN M482_2124 ENOG4105CHM Aminotransferase M482_2128 ENOG4105KME endoribonuclease L-psp M482_213 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein M482_2145 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) M482_2146 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) M482_2147 ENOG4105VCC 30S ribosomal protein S21 M482_215 ENOG4105Y3U Transglycosylase-associated protein M482_2150 ENOG4107ZVW dihydroneopterin aldolase M482_2153 ENOG4106MWK domain protein M482_2154 ENOG4105I7R Adenylate cyclase M482_2157 ENOG4105DVH amino acid M482_2158 ENOG4105W0Z cytoplasmic protein M482_2161 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b M482_2162 ENOG4106032 Glutathionylspermidine synthase M482_2165 ENOG4105DFG type I secretion outer membrane protein M482_2166 ENOG41087AY ADP-Ribose pyrophosphatase M482_2167 ENOG4108SX3 cytoplasmic protein M482_2168 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) M482_2169 ENOG4105IPS esterase M482_217 ENOG4105N1F Hnh endonuclease M482_2170 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M482_2171 ENOG4105CR8 Transcriptional regulator M482_2172 ENOG4105NF4 modulator of drug activity M482_2173 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M482_2174 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase M482_2175 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) M482_2178 ENOG4105CV8 reductase M482_2179 ENOG4108I6A alcohol dehydrogenase M482_2180 ENOG4105CF7 AraC family transcriptional regulator M482_2181 ENOG4108K81 inner membrane protein YghB M482_2182 ENOG4105C28 cystathionine M482_2183 ENOG4105CWK Biopolymer transport protein, ExbB M482_2185 ENOG4108ZZF transport protein (ExbD) M482_219 ENOG4105CXG d-lactate dehydrogenase M482_22 ENOG4105C3M thioredoxin reductase M482_220 ENOG41061WM D-Alanyl-D-Alanine M482_2200 ENOG4106PG1 outer membrane usher protein M482_2201 ENOG4106P2F Pfam:Pili_assembly_C M482_2204 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein M482_2208 ENOG4105D00 flagellar biosynthetic protein flhB M482_2209 ENOG4105D19 Role in flagellar biosynthesis (By similarity) M482_2210 ENOG4105VS8 Flagellar biosynthetic protein fliq M482_2211 ENOG4105CN7 Flagellar biosynthetic protein FliP M482_2212 ENOG4105DD5 Flagellar motor switch protein M482_2214 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family M482_2216 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) M482_2219 ENOG4108JIR Flagellum-specific ATP synthase M482_222 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) M482_2223 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA M482_2224 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) M482_2225 ENOG4108ZC9 flagellar basal-body rod protein flgc M482_2226 ENOG4105W00 Flagellar hook capping protein M482_2227 ENOG4105BZE flagellar hook protein, FlgE M482_2228 ENOG4108KPB Flagellar basal-body rod protein FlgF M482_2229 ENOG4105CGA flagellar basal-body rod protein FlgG M482_2230 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) M482_2231 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) M482_2233 ENOG4105E1Q flagellar hook-associated protein M482_2237 ENOG4108M3R transcriptional activator CadC M482_2242 ENOG410804A Flagellar hook-associated 2 domain-containing protein M482_2248 ENOG4107RD7 Flagellar Motor Protein, MotA M482_225 ENOG4105EAA nucleoside M482_2253 ENOG4108XTF Outer Membrane Lipoprotein M482_2256 ENOG4105DQ6 Transposase M482_2257 ENOG4105CT4 transporter M482_2259 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) M482_226 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) M482_2260 ENOG4105DUU IucA IucC family protein M482_2279 ENOG4105CDV Ompa motb domain protein M482_228 ENOG4105CN8 Transcriptional regulator M482_2281 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M482_229 ENOG4105C94 Transporter M482_2290 ENOG4105CXN decarboxylase M482_2291 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator M482_2292 ENOG4105C2J ABC transporter M482_2293 ENOG4105CNN ABC, transporter M482_2298 ENOG4105CEN a g-specific adenine glycosylase M482_23 ENOG4108JJ9 ABC, transporter M482_2300 ENOG41090ED Protein with unknown function (DUF469) M482_2301 ENOG4105CSV Glutaminase M482_2302 ENOG4105K33 Periplasmic Protein M482_2303 ENOG4105K33 Periplasmic Protein M482_2304 ENOG4105EUK rtx toxin RtxA M482_2305 ENOG4105CSA Coproporphyrinogen iii oxidase M482_2306 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) M482_2308 ENOG4108VIA integral membrane protein M482_2309 ENOG4105II7 pyrroline-5-carboxylate reductase M482_2310 ENOG4105DFA alanine racemase domain protein M482_2311 ENOG4105CZX twitching motility protein M482_2313 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) M482_2316 ENOG4105D7Z glutathione synthase M482_2317 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) M482_2318 ENOG4105RWS endonuclease I M482_2322 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) M482_2324 ENOG4108K0D peptidase, M48 M482_2325 ENOG4105CV1 Transketolase (EC 2.2.1.1) M482_2329 ENOG4105D2N Aldolase M482_233 ENOG4108RS6 transposase M482_2330 ENOG4105D64 Mechanosensitive ion channel M482_2332 ENOG4105MPN Membrane M482_2334 ENOG4105E66 phosphoriboisomerase A M482_2335 ENOG4108JQ1 Dehydrogenase M482_2336 ENOG4108RS6 transposase M482_2337 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase M482_234 ENOG4105HFZ Membrane M482_2340 ENOG4107RAQ aminopeptidase M482_2341 ENOG4105D0A hydroxylase M482_2342 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family M482_235 ENOG4108ZAF Molybdopterin M482_2350 ENOG4108UT2 hemolysin iii M482_2353 ENOG4105Y75 tpr repeat protein M482_2354 ENOG4105E3W Two component transcriptional regulator (Winged helix family M482_2355 ENOG4105EB3 Histidine kinase M482_2356 ENOG4105CT7 inner membrane cred family protein M482_2357 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) M482_2358 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) M482_2359 ENOG4105T95 Thiol disulfide interChange protein M482_236 ENOG4105M00 molybdopterin converting factor, subunit 1 M482_2360 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) M482_2364 ENOG4105DFP Integrase M482_2368 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation M482_2369 ENOG4105WJ3 XRE family Transcriptional regulator M482_238 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) M482_2386 ENOG4105NTW Transcriptional regulator M482_2387 ENOG4108UY0 (LipO)protein M482_2389 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator M482_2390 ENOG4105CNN ABC, transporter M482_2393 ENOG4107FKK extracellular solute-binding protein family 1 M482_2395 ENOG4105EG2 ABC transporter, permease M482_2397 ENOG4105C4C beta-galactosidase M482_2398 ENOG4105C4C beta-galactosidase M482_24 ENOG4108JJ8 (ABC) transporter M482_240 ENOG4105CHW UPF0052 protein M482_2400 ENOG4105CI1 PTS System M482_2402 ENOG4105ETE Transcriptional regulator (LacI family M482_2404 ENOG4105DPW Major facilitator superfamily MFS_1 M482_2405 ENOG4105ETE Transcriptional regulator (LacI family M482_2408 ENOG4105D2N Aldolase M482_241 ENOG4105VYA Uncharacterized conserved protein (DUF2132) M482_2410 ENOG4105ENH Sulfatase M482_2411 ENOG4105C4X radical SAM domain protein M482_2413 ENOG4105CHR reductase M482_2414 ENOG4105CE4 GlcNAc 6-P deacetylase M482_2415 ENOG4108YTN IIa component M482_2416 ENOG4105F3R pts system mannose fructose sorbose family iid M482_2417 ENOG4105ETZ PTS System M482_2418 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB M482_2419 ENOG4105E70 isomerase M482_242 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) M482_2420 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of M482_2421 ENOG4105E98 transcriptional regulator DeoR family M482_2422 ENOG4105CBG Sulfatase M482_243 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) M482_2430 ENOG4107B2H carbonic anhydrase M482_2434 ENOG4107QHF type ii secretion system protein e M482_2436 ENOG4105D7Q type ii secretion system M482_244 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) M482_245 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) M482_2451 ENOG4105C8Q Methyl-accepting chemotaxis M482_2453 ENOG4105EJC lysr family transcriptional regulator M482_2454 ENOG4105RQF LysR family Transcriptional regulator M482_2455 ENOG4105F27 Major Facilitator M482_2456 ENOG41060NJ transcriptional regulator M482_2457 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) M482_2463 ENOG4105CPC Aldo Keto reductase M482_2466 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase M482_2474 ENOG4105DSY exodeoxyribonuclease V, gamma M482_2475 ENOG4107QXK peptidase M482_2476 ENOG4107QKA exodeoxyribonuclease V beta M482_2477 ENOG4107QYX exodeoxyribonuclease v alpha M482_2481 ENOG4107QZM n-acetylglutamate synthase M482_2482 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase M482_2485 ENOG4105CA3 membrane-bound lytic murein transglycosylase M482_2486 ENOG4105CUZ uba thif-type nad fad binding protein M482_2487 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) M482_2488 ENOG4105C9B Cysteine desulfurase M482_2490 ENOG4105ETT transcriptional Regulator, LysR family M482_2491 ENOG4105M08 Membrane M482_2493 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease M482_2494 ENOG4105EWT decarboxylase family M482_2497 ENOG4108RS6 transposase M482_2498 ENOG4105WP7 tRNA pseudouridine synthase C M482_2499 ENOG4105DR9 pseudouridine synthase M482_250 ENOG4108K4B hydrolase M482_2500 ENOG4105QDK Flavodoxin M482_2504 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) M482_2510 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) M482_2511 ENOG4105KNE Phosphatidate cytidylyltransferase M482_2512 ENOG4105DZP Membrane-associated zinc metalloprotease M482_2514 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) M482_2518 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) M482_252 ENOG4105E0C molybdate abc transporter M482_2520 ENOG4105C0B DNA polymerase III (alpha subunit) M482_2522 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase M482_2523 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) M482_2525 ENOG4105M1T rho-binding antiterminator M482_2527 ENOG4108VWS Yaeq family M482_2528 ENOG4108YZN class I peptide chain release factor M482_2529 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion M482_253 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein M482_2531 ENOG4108R96 Methyltransferase, YaeB family M482_2532 ENOG4108R8X outer membrane lipoprotein M482_2533 ENOG4105D01 (LipO)protein M482_2534 ENOG4108UMI ABC transporter, permease M482_2536 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase M482_254 ENOG410680R Protein of unknown function (DUF2592) M482_2542 ENOG4105CV8 reductase M482_2545 ENOG4105E9H Lytic Murein transglycosylase M482_2547 ENOG4105D1A Methyltransferase M482_2549 ENOG4108JDX DNA polymerase iii, epsilon subunit M482_255 ENOG4105F4R Transcriptional regulator mode M482_2551 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease M482_2553 ENOG4105GIJ Glycine betaine M482_2554 ENOG4108HQS Glycine betaine M482_2555 ENOG4108IJ7 Glycine betaine M482_2556 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) M482_256 ENOG4105DKW ABC transporter M482_2561 ENOG4108WMJ Protein of unknown function (DUF2002) M482_2562 ENOG4108SAJ Protein of unknown function (DUF1198) M482_2564 ENOG4105VEQ Cold shock protein M482_2565 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein M482_2566 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component M482_2567 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component M482_2568 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) M482_2569 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) M482_2576 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) M482_2580 ENOG4105XXV Acid-resistance protein M482_2581 ENOG4107SVH Potassium channel protein M482_2582 ENOG41086WQ Protein CrcB homolog M482_2583 ENOG41085Q9 Protein CrcB homolog M482_2584 ENOG4105VZJ PTS System M482_2585 ENOG4105CK1 PTS System M482_2586 ENOG4105VCP PTS System M482_2587 ENOG4105EZV Transcriptional regulator M482_2592 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 M482_2596 ENOG4105EEX Two component transcriptional regulator (Winged helix family M482_2597 ENOG4105C08 Histidine kinase M482_2598 ENOG4105C08 Histidine kinase M482_26 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) M482_260 ENOG4105CMR udp-glucose 4-epimerase M482_2602 ENOG4105XIQ Protein of unknown function (DUF2517) M482_2603 ENOG4107SEY Conserved Protein M482_2604 ENOG4105CVP deoxyribo-dipyrimidine photolyase M482_2605 ENOG4107RF4 Phosphodiesterase M482_2606 ENOG4107QNR UPF0135 protein M482_2608 ENOG4105P4J Allophanate hydrolase, subunit 1 M482_2609 ENOG4107R7A Allophanate hydrolase subunit 2 M482_261 ENOG4105F0Z galactose-1-phosphate uridylyltransferase M482_2620 ENOG4105C1J atp-dependent rna helicase M482_2622 ENOG4108IYU L-aspartate oxidase M482_2624 ENOG41069PW sigma-e factor negative regulatory protein M482_2625 ENOG4105VQK sigma E regulatory protein, MucB RseB M482_2626 ENOG4105WMJ Positive regulator of sigma E, RseC MucC M482_2629 ENOG4105C3F Signal peptidase i M482_2633 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) M482_2635 ENOG4108RS6 transposase M482_2636 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) M482_2639 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) M482_264 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) M482_2642 ENOG4105DAN ATP-dependent protease M482_2644 ENOG4108RS6 transposase M482_2645 ENOG4105UYK outer membrane protein a M482_2647 ENOG4108RZ1 DNA transformation protein M482_2648 ENOG4105EM2 membrane M482_2649 ENOG410901E Membrane M482_2650 ENOG41088T4 Helicase IV M482_2652 ENOG4108Q67 UPF0319 protein M482_2653 ENOG4105K4P CoA-binding domain protein M482_2657 ENOG4108Z0T Part of a sulfur-relay system (By similarity) M482_2659 ENOG4108BUD transposase M482_2666 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) M482_2667 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) M482_2668 ENOG4105CHR reductase M482_2669 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase M482_267 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) M482_2671 ENOG4108KQ6 Enoyl-CoA hydratase M482_2672 ENOG4105CHR reductase M482_2674 ENOG41062T2 Acyl carrier protein M482_2675 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase M482_268 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) M482_2681 ENOG4105CDV Ompa motb domain protein M482_2683 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M482_269 ENOG4105PGM cation diffusion facilitator family transporter M482_270 ENOG4106Z1T Nicotinamide Mononucleotide Transporter M482_2702 ENOG4105C5H ABC transporter M482_2704 ENOG4105D06 uba thif-type nad fad binding protein M482_2705 ENOG4105CVM Molybdenum cofactor synthesis domain protein M482_2707 ENOG4105C19 ABC transporter M482_2708 ENOG4105ENT Efflux transporter rnd family, mfp subunit M482_2713 ENOG4105EGI Transcriptional regulator M482_2714 ENOG4105CBP Major Facilitator M482_2716 ENOG4105DHF Membrane M482_2719 ENOG4108HWV )-transporter M482_2722 ENOG4107SDZ Galactoside transport system permease protein mglC M482_2723 ENOG4107GZ4 SanA protein M482_2726 ENOG41067MG lrgb family M482_2728 ENOG4105E5W Transporter M482_2732 ENOG4108RS6 transposase M482_2734 ENOG4105D1F ATP-binding protein M482_2737 ENOG4108GAE asmA family M482_2738 ENOG4105EE5 Membrane protein terC M482_2739 ENOG4108819 ferric iron reductase M482_274 ENOG4105UFD tol-pal system protein YbgF M482_2740 ENOG4105DY8 decarboxylase M482_2741 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) M482_2743 ENOG4105DUU IucA IucC family protein M482_2744 ENOG4105E0A ABC, transporter M482_2745 ENOG4105TVJ transport system, permease M482_2746 ENOG4105DQ5 transport system permease protein M482_2747 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) M482_2748 ENOG4105CNM Receptor M482_2749 ENOG4105DUU IucA IucC family protein M482_275 ENOG4105KCK Peptidoglycan-associated lipoprotein M482_2750 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase M482_2751 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase M482_2752 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) M482_2753 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase M482_2756 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) M482_2757 ENOG4105ECC imidazole-glycerol-phosphate dehydratase M482_2759 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) M482_2761 ENOG4108535 NAD dependent epimerase/dehydratase family M482_2763 ENOG4105CNN ABC, transporter M482_2764 ENOG4105C2J ABC transporter M482_2765 ENOG4105C2J ABC transporter M482_2766 ENOG4107SCQ Iron-containing alcohol dehydrogenase M482_2768 ENOG4105CUB amino acid M482_2769 ENOG4105CJB Exodeoxyribonuclease I M482_277 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA M482_277 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA M482_2772 ENOG4105TNG K13735 adhesin invasin M482_2774 ENOG4105CSP Major Facilitator Superfamily M482_2775 ENOG4105KIR Thiol-disulfide oxidoreductase dcc M482_2776 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr M482_2778 ENOG4105DIA mandelate racemase muconate lactonizing M482_278 ENOG4105M8F Biopolymer transport protein exbD tolR M482_2782 ENOG4105UQX Mate efflux family protein M482_2786 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme M482_2788 ENOG4108KX4 response regulator M482_2789 ENOG4105CG6 trap dicarboxylate transporter dctm subunit M482_279 ENOG4105E02 MotA TolQ exbB proton channel M482_2791 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit M482_2792 ENOG4108TSE Transferase M482_2796 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) M482_28 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M482_280 ENOG4107YD3 Thioesterase M482_2802 ENOG4108RS6 transposase M482_2803 ENOG4105BZ1 (ABC) transporter M482_2807 ENOG4105N4N Protein of unknown function (DUF2766) M482_2808 ENOG4105TIK M482_2809 ENOG41064PC M482_281 ENOG4105KJB cyd operon protein YbgE M482_2812 ENOG4105C85 amino acid M482_2815 ENOG4105VEQ Cold shock protein M482_2816 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase M482_2817 ENOG4105DHI Methyltransferase M482_2819 ENOG4105BZU Histidine kinase M482_2823 ENOG4105F3R pts system mannose fructose sorbose family iid M482_2824 ENOG4105ETZ PTS System M482_2825 ENOG4108EQA pts system M482_2826 ENOG4108EQA pts system M482_2827 ENOG4105EE5 Membrane protein terC M482_2828 ENOG4108V8F Transcriptional regulator, MarR family M482_283 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii M482_2831 ENOG4105C26 Dehydrogenase M482_2832 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase M482_2837 ENOG4105EFA 4-hydroxyphenylacetate M482_2838 ENOG4107UWN reductase M482_2839 ENOG4105EJQ L-serine dehydratase M482_284 ENOG4105C4M (Ubiquinol oxidase) subunit I M482_2841 ENOG4105CRQ synthase (Component I) M482_2844 ENOG4105C1J atp-dependent rna helicase M482_2845 ENOG4105X2V dna damage-inducible protein M482_2848 ENOG4105CUG Oligopeptidase b M482_285 ENOG4108RS6 transposase M482_2850 ENOG4105MPK DNA polymerase III subunit theta M482_2851 ENOG41090A1 ferritin M482_2852 ENOG4105FXM Copper resistance protein M482_2854 ENOG4105NKT exported protein M482_2857 ENOG4105D00 flagellar biosynthetic protein flhB M482_2858 ENOG4105D7B Flagellar biosynthesis protein flha M482_2859 ENOG4105W13 flagellar protein M482_286 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha M482_2863 ENOG4105QVD Flagella synthesis protein FlgN M482_2864 ENOG4105M9M anti-sigma28 factor FlgM M482_2865 ENOG4105CKS Flagella basal body P-ring formation protein flgA M482_2866 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) M482_2867 ENOG4108ZC9 flagellar basal-body rod protein flgc M482_2868 ENOG4105W00 Flagellar hook capping protein M482_2869 ENOG4105BZE flagellar hook protein, FlgE M482_2870 ENOG4108KPB Flagellar basal-body rod protein FlgF M482_2871 ENOG4105CGA flagellar basal-body rod protein FlgG M482_2874 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj M482_2875 ENOG4105E1Q flagellar hook-associated protein M482_2876 ENOG4105DTJ flagellar hook-associated protein M482_2877 ENOG4105DKT Transcriptional regulator M482_288 ENOG4105C7S Dehydrogenase M482_2880 ENOG4105CNN ABC, transporter M482_2882 ENOG4105C2J ABC transporter M482_2883 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane M482_2884 ENOG4108MGF sugar kinase M482_2887 ENOG4105D19 Role in flagellar biosynthesis (By similarity) M482_2888 ENOG4105VS8 Flagellar biosynthetic protein fliq M482_2889 ENOG4105CN7 Flagellar biosynthetic protein FliP M482_289 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 M482_2891 ENOG4105DD5 Flagellar motor switch protein M482_2892 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) M482_2893 ENOG4107ZI8 flagellar basal body-associated protein flil M482_2894 ENOG4105WF4 Flagellar hook-length control protein M482_2895 ENOG4105GSA Flagellar export protein flij M482_2896 ENOG4108JIR Flagellum-specific ATP synthase M482_2897 ENOG41090PJ Flagellar assembly protein M482_2898 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) M482_2899 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) M482_290 ENOG4105E33 succinate dehydrogenase M482_2900 ENOG4105VQ0 flagellar hook-basal body complex protein fliE M482_2904 ENOG4105DHT Metal Dependent Phosphohydrolase M482_2907 ENOG4105MQ3 flagellar protein FliS M482_2908 ENOG4105DTS flagellar hook-associated M482_2909 ENOG4105I03 Flagellin M482_2910 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) M482_2911 ENOG4108M9K flagella biosynthesis protein FliZ M482_2912 ENOG4105K6H D-cysteine desulfhydrase M482_2913 ENOG4105EAB amino acid AbC transporter M482_2914 ENOG4105EAB amino acid AbC transporter M482_2915 ENOG4105E5Q amino acid AbC transporter M482_2916 ENOG4105CDA abc transporter atp-binding protein M482_2919 ENOG4105C26 Dehydrogenase M482_292 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein M482_2921 ENOG4105CK7 Sodium proline symporter M482_2924 ENOG4105DBE peroxidase M482_2927 ENOG4105C85 amino acid M482_2929 ENOG4108T1M outer membrane protein x M482_293 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit M482_2931 ENOG4105RA2 Membrane M482_2932 ENOG4105XVG cytoplasmic protein M482_2933 ENOG4105WH1 Two component transcriptional regulator luxr family M482_294 ENOG4105BZN citrate synthase M482_2944 ENOG4108WC9 type VI secretion system effector, hcp1 family M482_296 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) M482_2963 ENOG4105FDP GntR family transcriptional regulator M482_2964 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) M482_2967 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component M482_2968 ENOG4108IJ9 (ABC) transporter M482_297 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) M482_298 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) M482_2980 ENOG4107ZSV Receptor M482_2981 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase M482_2985 ENOG4105C0W non-ribosomal peptide synthetase M482_2988 ENOG4105BZ1 (ABC) transporter M482_2989 ENOG4105EYM Major Facilitator superfamily M482_2995 ENOG4108MQF Chaperone M482_2997 ENOG4105CW0 outer membrane usher protein M482_3 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) M482_30 ENOG4105VEQ Cold shock protein M482_300 ENOG4108Z1B Cyclase dehydrase M482_3000 ENOG4105BZU Histidine kinase M482_3001 ENOG4108Q9V regulatoR M482_3003 ENOG4105CYC Transferase M482_3004 ENOG4105DJG MaoC domain protein dehydratase M482_3009 ENOG4107RGD Major Facilitator superfamily M482_3012 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) M482_3013 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family M482_3014 ENOG4105C85 amino acid M482_3015 ENOG4105MVE transcriptional regulator M482_3016 ENOG4105CSV Glutaminase M482_3019 ENOG4107SJW iron permease, FTR1 M482_3022 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) M482_3024 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) M482_3028 ENOG4105H1N peptidase, M24 M482_3029 ENOG4108TUY outer membrane protein PgaA M482_303 ENOG4105DFP Integrase M482_3030 ENOG4107BJW polysaccharide deacetylase M482_3031 ENOG4105CND Glycosyl transferase, family 2 M482_3032 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD M482_3035 ENOG4105D5M phosphate starvation-inducible protein M482_3036 ENOG4108RS6 transposase M482_3037 ENOG4105EWV Sodium calcium exchanger membrane region M482_3039 ENOG4105BZU Histidine kinase M482_3040 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family M482_3054 ENOG4105CZE histidine utilization repressor M482_3055 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) M482_3056 ENOG41090B9 response to stress M482_3058 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) M482_3059 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) M482_3060 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase M482_3074 ENOG4108WF3 methyltransferase M482_3083 ENOG4105GR3 Histidine kinase M482_3088 ENOG4105CK6 Two component transcriptional regulator (Winged helix family M482_3089 ENOG4105ENX hydrolase M482_3098 ENOG4105C3G gtp-binding protein M482_3100 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria M482_3101 ENOG4105C5T Phosphoribosyl pyrophosphate synthase M482_3106 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) M482_3107 ENOG4108YY7 Invasion gene expression up-regulator SirB M482_3108 ENOG41063JG Transcriptional regulator M482_3110 ENOG4105CHH sulfate transporter M482_3114 ENOG4105EG2 ABC transporter, permease M482_3115 ENOG4105F38 ABC transporter, permease M482_3117 ENOG4108RS6 transposase M482_3118 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) M482_3119 ENOG4108QXE glycerophosphoryl diester phosphodiesterase M482_3120 ENOG4105E2R ROK family M482_3123 ENOG4107XHZ cytoplasmic chaperone TorD family protein M482_3124 ENOG4105F3T (LipO)protein M482_3126 ENOG4105D9U N-acetyltransferase M482_3127 ENOG4105EP9 oxidoreductase M482_3128 ENOG4105CJR Integral membrane protein (MviN M482_313 ENOG4105VUH addiction module killer protein M482_3132 ENOG4106ZCM YecM protein M482_3136 ENOG4105WJG Glutathione M482_3137 ENOG41081XQ Conserved Protein M482_3139 ENOG4108TIT dATP pyrophosphohydrolase M482_3142 ENOG4108RS6 transposase M482_3145 ENOG4105FAV ABC, transporter M482_3147 ENOG4105NXV High-affinity zinc uptake system protein M482_3148 ENOG4105DR5 peptidase M482_3149 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase M482_3150 ENOG4105CA9 Pyruvate kinase M482_3151 ENOG4106KNT transcriptional regulator M482_3152 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase M482_3154 ENOG4108UHU Aldolase M482_3157 ENOG4105M4H endoribonuclease L-psp M482_3158 ENOG4105DVT helicase M482_3159 ENOG41072GX Peptidase M22 Glycoprotease M482_3160 ENOG4105Y4Z Outer Membrane Lipoprotein M482_3161 ENOG4105CEY Amp-dependent synthetase and ligase M482_3162 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) M482_3163 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) M482_3164 ENOG4107QMS site-determining protein M482_3167 ENOG4105CVE Lytic murein transglycosylase M482_3168 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase M482_317 ENOG4105DFP Integrase M482_3170 ENOG4107R08 Integrase M482_3175 ENOG4105NY2 NinB protein M482_3177 ENOG4105HRS Antitermination protein M482_32 ENOG4105DJY efflux transporter, rnd family, mfp subunit M482_320 ENOG4105EV9 Alpha Beta Hydrolase M482_3205 ENOG4108RS6 transposase M482_322 ENOG4105NNH LexA regulated protein M482_3221 ENOG4105UZW Tail fiber assembly protein M482_3223 ENOG4105C3J Cysteine desulfurase M482_3229 ENOG4105ED1 spovr family M482_323 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) M482_3231 ENOG4105CNH Multidrug resistance protein MdtL M482_3232 ENOG4105EUB pirin domain protein M482_3233 ENOG4105HEI LysR family (Transcriptional regulator M482_3236 ENOG4105CYN Serine protein kinase M482_3237 ENOG4105GNX MltA-interacting MipA family protein M482_3238 ENOG4105DSB aldose 1-epimerase M482_324 ENOG41090R7 Ferric uptake M482_3241 ENOG4105VUT cytoplasmic protein M482_3242 ENOG4108RWI nicotinamidase M482_3243 ENOG4105HDK L-asparaginase M482_3244 ENOG4105D07 Signal peptide peptidase, SppA M482_3245 ENOG41069NU Nitroreductase M482_3246 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) M482_3247 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) M482_3248 ENOG4105MTM Protein of unknown function (DUF1496) M482_3249 ENOG4105M6F mutator MutT protein M482_3250 ENOG4105CGK Exodeoxyribonuclease III M482_3251 ENOG4105SKE transcriptional Regulator LysR family M482_3255 ENOG4105CIY formyltetrahydrofolate deformylase M482_3257 ENOG4105I93 response regulator M482_3258 ENOG4105C6Y Udp-glucose 6-dehydrogenase M482_3261 ENOG4107104 thymidine kinase M482_3262 ENOG4108EKI Dehydrogenase M482_3263 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein M482_3264 ENOG4107QSI ABC, transporter M482_3266 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component M482_3267 ENOG4105C3U ABC transporter M482_3268 ENOG4108JQ7 (ABC) transporter M482_3272 ENOG4108T1M outer membrane protein x M482_3275 ENOG4105K9H YciI-like protein M482_3277 ENOG410822N TonB family M482_3279 ENOG4105NAU thioesterase Superfamily protein M482_3284 ENOG4105EIF outer membrane protein W M482_3288 ENOG4105DK0 Indole-3-glycerol phosphate synthase M482_3290 ENOG4105DDQ anthranilate synthase M482_3292 ENOG4105DB7 PHP domain protein M482_3293 ENOG4107RTD sua5 ycio yrdc ywlc family protein M482_3294 ENOG4105FE9 pseudouridine synthase M482_3295 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase M482_3296 ENOG4105UBK short-chain dehydrogenase reductase M482_3297 ENOG4105ERU peptidase M482_3298 ENOG4105RKX Protein of unknown function (DUF2498) M482_33 ENOG4108MJ5 VirK protein M482_330 ENOG4105CI1 PTS System M482_3300 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) M482_3301 ENOG4108RS6 transposase M482_3302 ENOG4107R11 Transcriptional regulator M482_3304 ENOG4107QM5 aconitate hydratase M482_3305 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) M482_3306 ENOG4105EYK Phosphatidylglycerophosphatase B M482_3307 ENOG4105Q4A inner membrane protein yciS M482_3308 ENOG4105CFV Tetratricopeptide repeat protein M482_3311 ENOG4108ZJT translation initiation factor, Sui1 M482_3313 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase M482_3315 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) M482_3316 ENOG4105VCD cytoplasmic protein M482_3317 ENOG4105D22 carbon starvation protein M482_3319 ENOG4105CSP Major Facilitator Superfamily M482_332 ENOG4105CE4 GlcNAc 6-P deacetylase M482_3320 ENOG4105EXW epimerase dehydratase M482_3321 ENOG4105CSM endonuclease III M482_3323 ENOG4108UQQ Electron transport complex M482_3324 ENOG4105D6A Electron transport complex M482_3325 ENOG4105UEI Transcriptional Regulator AraC Family M482_3329 ENOG4105M9B inner membrane protein ydgK M482_333 ENOG4105E2R ROK family M482_3330 ENOG4108JJA ABC, transporter M482_3331 ENOG4105BZ1 (ABC) transporter M482_3333 ENOG4105C42 Type I secretion membrane fusion protein (HlyD M482_3334 ENOG4108JJA ABC, transporter M482_3338 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator M482_334 ENOG4105D4U had-superfamily hydrolase, subfamily iia M482_3340 ENOG4105CNN ABC, transporter M482_3341 ENOG4105CNN ABC, transporter M482_3343 ENOG4105D9R oxidoreductase M482_3344 ENOG4105DHU Bile acid M482_3346 ENOG4106J39 exported protein M482_3347 ENOG4105EIP mannose-6-phosphate isomerase M482_3348 ENOG4105C9Q fumarate hydratase class II M482_3349 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) M482_335 ENOG4105CAQ asparagine synthetase M482_3350 ENOG4105D94 Major Facilitator Superfamily M482_3351 ENOG4106NZI LysR family Transcriptional regulator M482_3352 ENOG4105DAG ROK family M482_3354 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) M482_3355 ENOG4105CMQ Chloride channel M482_3356 ENOG4105KBG Protein of unknown function (DUF1161) M482_3357 ENOG41060NJ transcriptional regulator M482_3359 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator M482_3360 ENOG4107UWC ABC, transporter M482_3361 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component M482_3363 ENOG4105FYV Amp nucleosidase M482_3369 ENOG4105C7K acetolactate synthase M482_3370 ENOG4105M71 acetolactate synthase 1 regulatory subunit M482_3371 ENOG4105PAD Hydrolase M482_3374 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) M482_3375 ENOG4105DS0 Transcriptional regulator, Crp Fnr family M482_3376 ENOG4105Q9Y Universal stress protein M482_3377 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) M482_3378 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) M482_3379 ENOG4105C5D exported protein M482_3380 ENOG4105D5Q Arginine ornithine antiporter M482_3382 ENOG4107EXC regulatoR M482_3383 ENOG4105JJR Histidine kinase M482_3384 ENOG4105CTD carboxy-peptidase M482_3389 ENOG4105DS1 cytochrome b561 M482_3391 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap M482_3394 ENOG4105CQ7 ATP-dependent helicase M482_3396 ENOG4105DKT Transcriptional regulator M482_3397 ENOG4105DEI Mannitol dehydrogenase M482_3398 ENOG4105WXT Conserved Protein M482_3399 ENOG410689M (LipO)protein M482_34 ENOG4105CPB ATP-dependent endonuclease of the OLD family M482_3400 ENOG4107H52 Dicarboxylate transport M482_3401 ENOG4105C5I Dehydrogenase M482_3402 ENOG41090X5 Heat shock protein hslJ M482_3404 ENOG4105KT7 mgtC SapB transporter M482_3406 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) M482_3412 ENOG4107QSI ABC, transporter M482_3413 ENOG4105KXI murein peptide amidase A M482_3414 ENOG4107S8C mandelate racemase muconate lactonizing M482_3415 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) M482_342 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family M482_3423 ENOG4105CM6 amino acid regulated cytosolic protein M482_3425 ENOG4105FM1 phage shock protein C M482_3426 ENOG4105YYT phage shock protein B M482_3427 ENOG41087YS Phage shock protein A M482_3428 ENOG4105E51 psp operon transcriptional activator M482_3430 ENOG4108HIY periplasmic M482_3431 ENOG4108I5W peptide transport system, permease protein M482_3432 ENOG4108EU3 peptide transport system, permease M482_3433 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein M482_3434 ENOG4108JQ2 peptide transport system atp-binding protein M482_3435 ENOG4105Q4T oxidoreductase M482_3437 ENOG4105DUX Transporter M482_3438 ENOG41069YE inner membrane protein yohC M482_3439 ENOG4108ZR5 Conserved Protein M482_344 ENOG4105C9A Phoh family M482_3440 ENOG4108K3A Glutathione S-transferase M482_3444 ENOG410642K Lysozyme inhibitor M482_3446 ENOG4108XTF Outer Membrane Lipoprotein M482_3448 ENOG4107RGM aldo keto reductase M482_3449 ENOG4105XZD Fe-S protein M482_3450 ENOG4105DIJ Phosphoethanolamine transferase M482_3451 ENOG4108WUH Transcriptional regulator, TetR family M482_3452 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase M482_3454 ENOG4108UYE Lactoylglutathione lyase M482_3456 ENOG4105M2J Glutaredoxin M482_3458 ENOG4105K4H Nlp p60 protein M482_3459 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) M482_346 ENOG4108JU5 Magnesium and cobalt efflux protein M482_3462 ENOG4105F52 Transcriptional regulator M482_3463 ENOG4105CZQ inner membrane transport protein YdhC M482_3464 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase M482_3465 ENOG4108R6K riboflavin synthase, subunit alpha M482_3469 ENOG4105CA9 Pyruvate kinase M482_347 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) M482_3470 ENOG4105KMX major outer membrane lipoprotein M482_3474 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein M482_3477 ENOG4105JRK feS assembly protein SufD M482_3478 ENOG4105C3K feS assembly ATPase SufC M482_3479 ENOG4105DIW FeS assembly protein SUFB M482_348 ENOG4107RP9 extracellular solute-binding protein, family 3 M482_3480 ENOG4108Z4V iron-sulfur cluster assembly M482_3481 ENOG4105KA0 thioesterase Superfamily protein M482_3482 ENOG4105CQB FAD linked oxidase domain protein M482_3483 ENOG4105IPI Membrane M482_3484 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) M482_3486 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) M482_3489 ENOG4108QBX (LipO)protein M482_349 ENOG4105EAD ABC transporter M482_3497 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) M482_3498 ENOG4108V06 Glutathione peroxidase M482_35 ENOG4105DWU Membrane M482_350 ENOG4105DRP amino acid AbC transporter M482_3501 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) M482_3502 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) M482_3503 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) M482_3508 ENOG41087WU M482_351 ENOG4105CDA abc transporter atp-binding protein M482_3512 ENOG4105DSE periplasmic solute binding protein M482_3513 ENOG4105DIK (ABC) transporter M482_3514 ENOG4105CC5 ABC transporter M482_3515 ENOG4105CC5 ABC transporter M482_3516 ENOG4105FGM Fructosamine kinase M482_3517 ENOG4107PN8 YfeABCD locus regulator M482_3518 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 M482_352 ENOG4107PAI alpha helical protein M482_3520 ENOG4105M5J Cupin 2, conserved barrel domain protein M482_3522 ENOG4105CHR reductase M482_3523 ENOG41061NF Pectate lyase M482_3524 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component M482_3525 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component M482_3527 ENOG4105WEM extracellular solute-binding protein M482_3528 ENOG4108PU9 oligogalacturonate-specific porin M482_3529 ENOG4107K5X Membrane-bound metal-dependent hydrolase M482_3530 ENOG4108ETY sodium dicarboxylate symporter M482_3531 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase M482_3533 ENOG4105CAZ oligogalacturonide lyase M482_3534 ENOG4105C0R drug resistance transporter emrb qaca subfamily M482_3535 ENOG4108VEV chaperone M482_3538 ENOG4108VEV chaperone M482_3539 ENOG4105H8W Fimbrial protein M482_3542 ENOG4105CN1 protease M482_3544 ENOG4108ZGC gaf domain protein M482_3545 ENOG4105H2K paraquat-inducible protein a M482_3546 ENOG4105DY2 Paraquat-inducible protein b M482_355 ENOG4105DJF DNA polymerase III, delta' subunit M482_3550 ENOG4105GQR Chaperone M482_3553 ENOG4105WT8 Protein of unknown function (DUF1480) M482_3562 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) M482_3565 ENOG4105EUR Domain-Containing protein M482_3566 ENOG4105EUR Domain-Containing protein M482_3567 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase M482_3568 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) M482_3569 ENOG4108VYJ response regulator receiver protein M482_357 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) M482_3571 ENOG4105BZU Histidine kinase M482_3572 ENOG4105C8Q Methyl-accepting chemotaxis M482_3573 ENOG4105C8Q Methyl-accepting chemotaxis M482_3577 ENOG4105WWK YheO domain protein M482_3579 ENOG4105KME endoribonuclease L-psp M482_3580 ENOG4105R9B Major Facilitator M482_3581 ENOG4108V3W Chemotaxis protein, CheW M482_3582 ENOG4105CBS Chea signal transduction histidine kinase M482_3583 ENOG4105ER2 Ompa motb domain protein M482_3584 ENOG4107RD7 Flagellar Motor Protein, MotA M482_3585 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region M482_3586 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) M482_3587 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic M482_3588 ENOG4105KT7 mgtC SapB transporter M482_3589 ENOG4105C8Q Methyl-accepting chemotaxis M482_359 ENOG4105CJN penicillin-binding protein M482_3590 ENOG4105C8Q Methyl-accepting chemotaxis M482_3592 ENOG4105VEQ Cold shock protein M482_3595 ENOG4105GSJ Inner membrane protein ylaC M482_3596 ENOG4108XM1 transcriptional regulator AsnC family M482_3598 ENOG41061EV selenium-binding protein YdfZ M482_3599 ENOG4105D6F Phosphatase M482_360 ENOG4105CNI cell division protein FtsW M482_3601 ENOG4105KVH Transcriptional regulator M482_3602 ENOG4105ECR NmrA family M482_3603 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor M482_3605 ENOG4106NDP Transcriptional regulator M482_3606 ENOG4108HMX isocitrate dehydrogenase (NADP) M482_3607 ENOG4108R99 pseudouridine synthase M482_361 ENOG4105K6T rare lipoprotein A M482_3611 ENOG4107QTF adenylosuccinate lyase M482_3613 ENOG4105XJC Two component transcriptional regulator (Winged helix family M482_3615 ENOG4105EZE Cupin 4 family protein M482_3617 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) M482_3619 ENOG4105D60 lipoprotein releasing system transmembrane protein M482_362 ENOG4105DZ1 carboxypeptidase M482_3621 ENOG4105D60 lipoprotein releasing system transmembrane protein M482_3622 ENOG4108JA2 transcriptioN-repair coupling factor M482_3623 ENOG4107MBR 17 kDa surface antigen M482_3627 ENOG4105CEP NADH dehydrogenase M482_3629 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) M482_3632 ENOG41090DQ Lipoprotein M482_3633 ENOG4105K59 histidine triad (HIT) protein M482_3634 ENOG4105F9E Shikimate 5-dehydrogenase M482_3636 ENOG4105CI1 PTS System M482_3637 ENOG4105F8V Hydrolase, tatD family M482_3638 ENOG4107QRG dna polymerase iii M482_3640 ENOG4105HHA aminodeoxychorismate lyase M482_3641 ENOG4105YAZ 4-amino-4-deoxychorismate lyase M482_3642 ENOG4108RS6 transposase M482_3643 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) M482_3645 ENOG4105CHR reductase M482_3646 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase M482_3649 ENOG4105VGS 50s ribosomal protein l32 M482_3650 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein M482_3652 ENOG4105EI2 Pseudouridine synthase M482_3653 ENOG4107QQB Ribonuclease E M482_3654 ENOG41067V3 Antibiotic biosynthesis monooxygenase M482_3658 ENOG4105PVA Biofilm formation regulatory protein BssS M482_366 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) M482_3661 ENOG4105DSF transport protein M482_3665 ENOG4105VJY transcriptional regulator M482_3666 ENOG4107YC3 synthase M482_3667 ENOG4105ETT transcriptional Regulator, LysR family M482_3669 ENOG4105C54 Major Facilitator superfamily M482_367 ENOG4107Z6W Protein CrcB homolog M482_3671 ENOG4105CPC Aldo Keto reductase M482_3672 ENOG4108Y1S CRISPR-associated protein, Csy4 family M482_3673 ENOG4105M6W Crispr-associated protein, Csy3 family M482_3674 ENOG4105DZX CRISPR-associated protein, Csy2 family M482_3675 ENOG4105ENG CRISPR-associated protein, Csy1 family M482_3676 ENOG4107IIZ CRISPR-associated helicase, Cas3 M482_3677 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) M482_3678 ENOG4105CUY Mechanosensitive ion channel M482_368 ENOG4105VEQ Cold shock protein M482_3682 ENOG4105HY2 Glycosidase related protein M482_3683 ENOG4105DRS transport system, permease M482_3686 ENOG4105ETE Transcriptional regulator (LacI family M482_3688 ENOG4108IJ9 (ABC) transporter M482_3691 ENOG4105CKT filamentous hemagglutinin M482_3695 ENOG4105CKT filamentous hemagglutinin M482_3698 ENOG4105CKT filamentous hemagglutinin M482_3699 ENOG4105D5K Hemolysin activator protein M482_37 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) M482_370 ENOG4108N8T regulatoR M482_3700 ENOG4105E3J oxidoreductase M482_3701 ENOG4105DVW rieske (2Fe-2S) M482_3702 ENOG4105C94 Transporter M482_3703 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) M482_3704 ENOG4105EJC lysr family transcriptional regulator M482_3705 ENOG4105FKQ transcriptional regulator M482_3706 ENOG4105CNN ABC, transporter M482_3707 ENOG4105C2J ABC transporter M482_3709 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator M482_3710 ENOG4105CPQ Dehydrogenase M482_3714 ENOG4108T1M outer membrane protein x M482_3720 ENOG4107R0W ABC transporter M482_3721 ENOG4105E5Q amino acid AbC transporter M482_3722 ENOG4105CDA abc transporter atp-binding protein M482_3723 ENOG4107SDU Methyl-accepting chemotaxis M482_3725 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction M482_3726 ENOG4108MTB glycosyl transferase family M482_3727 ENOG4105CEY Amp-dependent synthetase and ligase M482_3729 ENOG4108IPT Naphthoate synthase M482_3732 ENOG4105E4F Isochorismate synthase M482_3734 ENOG4105TNS Conserved Protein M482_3736 ENOG4105C01 Dihydroxy-acid dehydratase M482_3739 ENOG4105C5I Dehydrogenase M482_3740 ENOG4105K2J Transcriptional regulator M482_3741 ENOG4105F32 YngK protein M482_3742 ENOG4105CHR reductase M482_3743 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family M482_3744 ENOG4108R66 Conserved Protein M482_3747 ENOG4105C8S subunit m M482_3748 ENOG4105D65 subunit l M482_375 ENOG4108JJ7 ABC transporter M482_3750 ENOG4107UFS subunit j M482_3753 ENOG4108IEH NADH dehydrogenase subunit g M482_3754 ENOG4107QIZ NADH dehydrogenase M482_3755 ENOG4105GKE subunit e M482_3757 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) M482_3759 ENOG4107NQ8 LysR family Transcriptional regulator M482_3760 ENOG4105CHM Aminotransferase M482_3762 ENOG4107QWE )-transporter M482_3763 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 M482_3767 ENOG4105C6K Malic enzyme M482_3768 ENOG4107P2S Transcriptional regulator M482_377 ENOG4105DH8 myo-inositol catabolism M482_3771 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC M482_3772 ENOG4105PTV Nudix Hydrolase M482_3773 ENOG4108RE9 Phosphodiesterase M482_3774 ENOG4108RE9 Phosphodiesterase M482_3776 ENOG4105ECP epimerase M482_3777 ENOG4108JEH abc transporter atp-binding protein M482_3778 ENOG4106YG3 ABC transporter M482_3779 ENOG4105DSP amino acid AbC transporter M482_3780 ENOG4105E89 ABC transporter M482_3781 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase M482_3782 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase M482_3783 ENOG4105E96 Colicin v production protein M482_3784 ENOG4108S3P Sporulation domain protein M482_3785 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase M482_3787 ENOG4105DQR SNARE associated Golgi M482_3789 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) M482_379 ENOG4105EDK PfkB domain protein M482_3792 ENOG410631K Membrane M482_3793 ENOG4106WZ1 flagella biosynthesis regulator M482_3796 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) M482_3798 ENOG4105MH2 YfcL protein M482_3799 ENOG4108BPE -transporting atpase M482_38 ENOG4105C7K acetolactate synthase M482_380 ENOG4105CK5 oxidoreductase M482_3800 ENOG4105EJ9 Membrane M482_3803 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) M482_3805 ENOG4108BY2 phosphohistidine phosphatase M482_3808 ENOG4105KZW UPF0381 protein M482_3809 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation M482_381 ENOG4105CNN ABC, transporter M482_3810 ENOG410903C (LipO)protein M482_3811 ENOG4105KWW Biogenesis protein M482_3812 ENOG4105KWW Biogenesis protein M482_3813 ENOG4107QX9 Thiol disulfide interChange protein M482_3814 ENOG4105DA4 cytochrome c-type biogenesis protein M482_3816 ENOG4105X3C heme exporter protein M482_3817 ENOG41060IM Heme exporter protein M482_3818 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) M482_382 ENOG4105C2J ABC transporter M482_3822 ENOG4108V0P LemA family M482_3824 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA M482_383 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator M482_3830 ENOG4105CS6 Rhs element vgr protein M482_384 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) M482_3843 ENOG4105CW0 outer membrane usher protein M482_3845 ENOG4105CW0 outer membrane usher protein M482_3846 ENOG4105GQR Chaperone M482_3848 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M482_3858 ENOG4105CVE Lytic murein transglycosylase M482_386 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) M482_3863 ENOG4108WC9 type VI secretion system effector, hcp1 family M482_3865 ENOG4107QY8 reductase M482_3866 ENOG4105QAX Iron-sulfur M482_3867 ENOG4107KGK dmso reductase anchor subunit M482_3868 ENOG4108NEM leader-binding protein dmsD M482_387 ENOG4105C26 Dehydrogenase M482_3870 ENOG4107Y60 (LipO)protein M482_3872 ENOG4106B0W Curli production assembly transport component CsgG M482_3874 ENOG4108VKM cytochrome b561 M482_3875 ENOG4105CHM Aminotransferase M482_3876 ENOG41072TH Protein of unknown function (DUF1479) M482_3879 ENOG4105C5Q Transcriptional regulator M482_3880 ENOG4105CPC Aldo Keto reductase M482_3883 ENOG4105D9N nucleoside M482_3889 ENOG4108RS6 transposase M482_3892 ENOG4105VRT cytoplasmic protein M482_3895 ENOG4105EXN Sulfate transport protein CysZ M482_3896 ENOG4105C6T cysteine synthase M482_3897 ENOG4105KZ7 phosphocarrier protein hpr M482_3899 ENOG4105C5Y PTS System M482_39 ENOG4105C5W Aldolase M482_3902 ENOG4105E0F Histidine kinase M482_3903 ENOG4105E3W Two component transcriptional regulator (Winged helix family M482_3904 ENOG4105DJY efflux transporter, rnd family, mfp subunit M482_3907 ENOG4105E1V na solute symporter M482_3909 ENOG4107RAQ aminopeptidase M482_3911 ENOG4105C87 Aminotransferase class I and II M482_3913 ENOG41062D9 Histidine kinase M482_3914 ENOG4105DPZ Two component transcriptional regulator (Winged helix family M482_3916 ENOG4105C6T cysteine synthase M482_3917 ENOG4108IJ6 ABC transporter M482_3918 ENOG4105ECW sulfate abc transporter M482_3919 ENOG4108I5D sulfate abc transporter M482_392 ENOG4105DN3 alpha-2-macroglobulin domain protein M482_3920 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein M482_3922 ENOG4105QEK Transcriptional regulator M482_3923 ENOG4108R66 Conserved Protein M482_3928 ENOG4105EZR dyp-type peroxidase family protein M482_3929 ENOG4105E7K (LipO)protein M482_393 ENOG4108JQB penicillin-binding protein 1C M482_3931 ENOG4105H4F exported protein M482_3937 ENOG4105C6K Malic enzyme M482_3939 ENOG4105CUW cytochrome C-TYPE protein M482_394 ENOG4105HVQ Regulatory factor of maltose metabolism M482_3940 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) M482_3942 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase M482_3943 ENOG4108ZNS ferredoxin-type protein NapF M482_3944 ENOG4105WH1 Two component transcriptional regulator luxr family M482_3946 ENOG4105BZS acriflavin resistance protein M482_3948 ENOG4105S2T inner membrane protein YbcI M482_3949 ENOG4105C4X radical SAM domain protein M482_3950 ENOG4105ENH Sulfatase M482_3951 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) M482_3952 ENOG4107Z33 ABC transporter, permease M482_3953 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC M482_3955 ENOG4105KUZ arsenate reductase M482_3961 ENOG4105CGZ zinc metallopeptidase M482_3963 ENOG4108RS6 transposase M482_3964 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) M482_3966 ENOG4105RH4 Glycine cleavage system transcriptional repressor M482_3967 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen M482_3970 ENOG4105C02 permease M482_3971 ENOG4105ERG peptidase m48, ste24p M482_3972 ENOG4105K89 arsenate reductase M482_3974 ENOG4108RS6 transposase M482_3977 ENOG4108V3E phosphoribosylglycinamide formyltransferase M482_3978 ENOG4108MK9 spermidine N(1)-acetyltransferase M482_3979 ENOG4108C80 FliB family M482_398 ENOG4108WC9 type VI secretion system effector, hcp1 family M482_3980 ENOG4108C80 FliB family M482_3982 ENOG4105E2Z phosphate ABC transporter (Permease M482_3983 ENOG4105C8U phosphate abc transporter M482_3984 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) M482_3985 ENOG4105C9X ppx gppa phosphatase M482_3986 ENOG4105CJW magnesium transporter M482_3987 ENOG4105R8A Heat shock protein M482_3988 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component M482_3989 ENOG4105F38 ABC transporter, permease M482_3991 ENOG4108JPW Aminotransferase M482_3993 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) M482_3999 ENOG4105EB3 Histidine kinase M482_40 ENOG4105CGD Nad-dependent epimerase dehydratase M482_4000 ENOG4105E3W Two component transcriptional regulator (Winged helix family M482_4001 ENOG4105KWI UPF0339 protein M482_4002 ENOG4105CFP Peptidase U32 M482_4004 ENOG4108ZGU inhibitor of vertebrate lysozyme M482_4006 ENOG4105DWF phosphomethylpyrimidine kinase M482_4015 ENOG4108WC9 type VI secretion system effector, hcp1 family M482_4016 ENOG4108RS6 transposase M482_4018 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) M482_4020 ENOG4105VPD cellular component movement M482_4023 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) M482_4024 ENOG4105N21 Membrane M482_403 ENOG4105EZE Cupin 4 family protein M482_4032 ENOG4108MGN ATP-binding component of a transport system M482_4033 ENOG4108MGN ATP-binding component of a transport system M482_4035 ENOG4105YYA enhanced serine sensitivity protein SseB M482_4037 ENOG4105WVQ Fe-S assembly protein IscX M482_4038 ENOG4108ZIT Ferredoxin, 2FE-2S M482_4039 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB M482_4042 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins M482_4043 ENOG4105C3J Cysteine desulfurase M482_4047 ENOG4105D7X high-affinity nickel-transporter M482_4048 ENOG41065CD Exported protein M482_4049 ENOG4105D8G Major Facilitator superfamily M482_4050 ENOG4108MN2 Stationary phase inducible protein CsiE M482_4053 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) M482_4056 ENOG4108M21 M482_4057 ENOG4108YZA Nitrogen regulatory protein pii M482_4058 ENOG4105C4K Nad synthetase M482_4059 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family M482_4060 ENOG4108SKK alpha helix protein M482_4061 ENOG4107WP9 Histidine kinase M482_4068 ENOG4108Z6B deaminase M482_4069 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB M482_4071 ENOG4106G6Q Transcriptional regulator M482_4072 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding M482_4073 ENOG4108RS6 transposase M482_4074 ENOG4108Q2G (LipO)protein M482_4075 ENOG4105DY2 Paraquat-inducible protein b M482_4076 ENOG4105F1S paraquat-inducible protein a M482_4077 ENOG4105C5H ABC transporter M482_4079 ENOG4105QVC MOSC domain-containing protein M482_408 ENOG4107QK4 glycoside hydrolase, family 3 domain protein M482_4080 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) M482_4082 ENOG4105CD8 aminopeptidase N M482_4086 ENOG4105CGF Aromatic amino acid aminotransferase M482_4087 ENOG4105C5X domain protein M482_4088 ENOG4105EAQ (twin-arginine translocation) pathway signal M482_4089 ENOG4105DIT ErfK YbiS YcfS YnhG family protein M482_4092 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) M482_4093 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) M482_4094 ENOG4106371 Methyltransferase M482_4095 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups M482_4097 ENOG4105W49 UPF0434 protein M482_4098 ENOG4105VEQ Cold shock protein M482_4099 ENOG4105E32 cytoplasmic protein M482_41 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase M482_4102 ENOG4108D1K outer membrane usher protein M482_4103 ENOG4108UIF Chaperone M482_4104 ENOG4106PHM regulatory protein M482_411 ENOG4107SET aldo keto reductase M482_412 ENOG4105EQ2 LysR family Transcriptional regulator M482_4141 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) M482_4143 ENOG4106CQM replication M482_4145 ENOG4105EQR Transposase IS116 IS110 IS902 M482_4154 ENOG4106RMF ParB family M482_4159 ENOG41073YN Protein of unknown function (DUF1380) M482_416 ENOG41077RS Phosphatase M482_4163 ENOG4105FEQ ParB domain protein nuclease M482_4166 ENOG4105UZW Tail fiber assembly protein M482_4167 ENOG4108X9F tail fiber protein M482_4167 ENOG4108X9F tail fiber protein M482_417 ENOG4105E8V Alpha Beta Hydrolase Fold protein M482_4174 ENOG4108NYK Tape measure protein M482_419 ENOG4108HPI phosphatidate Cytidylyltransferase M482_4192 ENOG4105FA0 parb-like partition protein M482_4193 ENOG4105FA0 parb-like partition protein M482_4194 ENOG4105CB5 ATP-dependent DNA helicase recG M482_42 ENOG41064MM (LipO)protein M482_420 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase M482_4205 ENOG4108RS6 transposase M482_4207 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) M482_4208 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) M482_4216 ENOG4106JVB Replication Protein M482_4222 ENOG4108RS6 transposase M482_4225 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) M482_4227 ENOG4105C2M dna polymerase I M482_4233 ENOG4106J5W DNA polymerase III (alpha subunit) M482_4253 ENOG4105CMM transposase M482_4255 ENOG4105CMM transposase M482_4263 ENOG4106CQM replication M482_4264 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) M482_427 ENOG4105WQ3 Rna-binding protein M482_4273 ENOG4105D13 transposase M482_4275 ENOG4108C33 Resolvase M482_4279 ENOG4105CMM transposase M482_428 ENOG4108RS6 transposase M482_4284 ENOG4105CMM transposase M482_4290 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB M482_4291 ENOG4105EZN Cobyrinic acid ac-diamide synthase M482_43 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) M482_431 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) M482_433 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) M482_434 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit M482_435 ENOG4105CV6 ABC transporter, permease M482_436 ENOG4108I0Y (ABC) transporter M482_437 ENOG4108UJV acyl-CoA thioesterase i M482_438 ENOG4105E1F short-chain dehydrogenase reductase M482_439 ENOG4107QR8 Thioredoxin M482_44 ENOG4105E5Z arginine transporter ATP-binding subunit M482_440 ENOG4107QX8 SPFH domain, Band 7 family protein M482_441 ENOG4105G5H Membrane M482_442 ENOG4108Z6Z Transcriptional regulator M482_443 ENOG4105C59 p-type ATPase M482_444 ENOG4105MBR gumn family M482_445 ENOG4108Z66 YbaK ebsC protein M482_448 ENOG4105CGH 5'-nucleotidase M482_449 ENOG4105CGH 5'-nucleotidase M482_45 ENOG4106PMH Extracellular solute-binding protein family 3 M482_450 ENOG4105CGH 5'-nucleotidase M482_451 ENOG4105EU0 Major facilitator Superfamily M482_452 ENOG4105EU0 Major facilitator Superfamily M482_453 ENOG4105CKD glutathione-regulated potassium-efflux system protein M482_454 ENOG4107RE1 Inosine-guanosine kinase M482_455 ENOG4108QY5 Ferric enterobactin transport protein M482_458 ENOG4105CJT Mannose-1-phosphate guanylyltransferase M482_459 ENOG4105C30 Nad-dependent epimerase dehydratase M482_46 ENOG4105GBT ABC transporter M482_460 ENOG4105C0K Gdp-mannose 4,6-dehydratase M482_461 ENOG4105C0K Gdp-mannose 4,6-dehydratase M482_462 ENOG4108TJN glycosyl transferase group 1 M482_469 ENOG4108SMP Nad-dependent epimerase dehydratase M482_47 ENOG4105DMR ABC, transporter M482_470 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase M482_471 ENOG4105FAW cDP-glucose 4,6-dehydratase M482_472 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase M482_473 ENOG4108EX3 reductase M482_479 ENOG4107QMP dna polymerase iii subunits gamma and tau M482_48 ENOG4108I0N Transporter, RarD family, DMT superfamily protein M482_481 ENOG4105WD1 Membrane M482_483 ENOG4105EGS Mechanosensitive ion channel M482_484 ENOG41090EX DsrE family M482_485 ENOG4108IG5 Transcriptional regulator M482_486 ENOG4105C1P efflux transporter, rnd family, mfp subunit M482_487 ENOG4105BZS acriflavin resistance protein M482_489 ENOG4105YK5 50S ribosomal protein L36 M482_49 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) M482_491 ENOG4108UKR Biofilm formation regulator YbaJ M482_492 ENOG4105KF5 hemolysin expression-modulating protein M482_493 ENOG41080UX Methyltransferase M482_494 ENOG4108MNP Glycoprotein polysaccharide metabolism M482_495 ENOG4105C29 acyl-CoA thioesterase M482_496 ENOG4105BZU Histidine kinase M482_497 ENOG4108YZA Nitrogen regulatory protein pii M482_498 ENOG4105BZ1 (ABC) transporter M482_499 ENOG4105BZ1 (ABC) transporter M482_50 ENOG410642S Nicotianamine synthase protein M482_500 ENOG4108XM1 transcriptional regulator AsnC family M482_501 ENOG4105C6T cysteine synthase M482_503 ENOG4108NFA extracellular solute-binding protein M482_505 ENOG4108TGP Thioesterase superfamily protein M482_506 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein M482_507 ENOG4105EIN peptidylprolyl cis-trans isomerase M482_51 ENOG4105E0A ABC, transporter M482_510 ENOG4105K70 DNA-binding protein M482_511 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) M482_516 ENOG4105M85 Bola protein M482_517 ENOG4105IEY (LipO)protein M482_518 ENOG4105EYM Major Facilitator superfamily M482_519 ENOG4108NFH Sugar hydrolase M482_52 ENOG4105DQ5 transport system permease protein M482_520 ENOG4105E2S oxidase) subunit II M482_521 ENOG4105BZ9 Cytochrome C oxidase, subunit I M482_522 ENOG4105CCU oxidase (Subunit III) M482_523 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) M482_525 ENOG4107RDB Major Facilitator M482_527 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) M482_528 ENOG4107S0N DJ-1 family M482_531 ENOG4105CTB Polyprenyl synthetase M482_534 ENOG4108ZAI phosphatidylglycerophosphatase a M482_535 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) M482_538 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) M482_543 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) M482_544 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) M482_545 ENOG4105VIE preprotein translocase, subunit YajC M482_547 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) M482_548 ENOG4108ZYK Acyl carrier protein phosphodiesterase M482_549 ENOG4105D3R alkyl hydroperoxide reductase M482_552 ENOG4105CHR reductase M482_553 ENOG4107R28 alpha amylase, catalytic region M482_554 ENOG4105C85 amino acid M482_555 ENOG4105CWM branched-chain amino acid transport system II carrier protein M482_557 ENOG4105BZU Histidine kinase M482_558 ENOG4105CK6 Two component transcriptional regulator (Winged helix family M482_559 ENOG4107RH8 nuclease SbcCD subunit D M482_560 ENOG4105EYH Exonuclease M482_561 ENOG4105DKQ ROK family M482_566 ENOG4105F2W methyltransferase M482_577 ENOG4105CIN aminoacyl-histidine dipeptidase M482_58 ENOG4105RBQ inner membrane protein ybjO M482_581 ENOG4105CJ2 (LipO)protein M482_585 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) M482_586 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) M482_587 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) M482_588 ENOG4105E7A Glutamine amidotransferase M482_589 ENOG4105F7V ErfK ybiS ycfS ynhG family protein M482_59 ENOG4105D38 putrescine abc transporter M482_591 ENOG4107QPN acyl-Coa dehydrogenase M482_594 ENOG4106YJS accessory processing protein M482_60 ENOG4105F38 ABC transporter, permease M482_602 ENOG4105CHM Aminotransferase M482_605 ENOG4105C5R Aminotransferase M482_608 ENOG4105C5R Aminotransferase M482_61 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) M482_610 ENOG4105E5Q amino acid AbC transporter M482_617 ENOG4105EQ0 Major Facilitator superfamily M482_618 ENOG4108UMN azlc family M482_619 ENOG4105ZED uncharacterized protein ygaH M482_62 ENOG4107RUE extracellular solute-binding protein family 1 M482_620 ENOG4105NTK Transcriptional repressor Mpra M482_621 ENOG4105CW7 secretion protein, HlyD family M482_622 ENOG4105C0R drug resistance transporter emrb qaca subfamily M482_623 ENOG4105EIB trna rrna methyltransferase M482_624 ENOG4105K63 Thioredoxin M482_625 ENOG4106IUH DTW domain containing protein M482_626 ENOG4105CD5 CoA-binding domain protein M482_627 ENOG4105JIM Phosphatidylserine synthase M482_628 ENOG4105T42 (LipO)protein M482_63 ENOG4108RMJ sensory transduction regulator M482_637 ENOG4108Y73 Membrane M482_639 ENOG4105C5Q Transcriptional regulator M482_64 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress M482_641 ENOG4105EHV domain protein M482_642 ENOG4107QN2 dihydrolipoyl dehydrogenase M482_643 ENOG4105YHG TonB family M482_644 ENOG4107QZV Type I secretion membrane fusion protein M482_647 ENOG4105X58 receptor M482_65 ENOG41090BQ Glutaredoxin M482_651 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase M482_655 ENOG4105DQ6 Transposase M482_66 ENOG4105D0C transport protein M482_660 ENOG4105CHV Transcription elongation factor NusA M482_666 ENOG4105EEI dihydropteroate synthase M482_667 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) M482_669 ENOG4105HBR Rna-binding protein M482_670 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) M482_671 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase M482_675 ENOG4105QYV Membrane M482_678 ENOG4105EAH synthase M482_68 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase M482_680 ENOG4105HVQ Regulatory factor of maltose metabolism M482_684 ENOG4105DFU Cell wall formation (By similarity) M482_686 ENOG4105F0N pyrophosphate phospho-hydrolase M482_687 ENOG4108ZHD aig2 family M482_688 ENOG4105MA0 exported protein M482_689 ENOG4105CFU surface antigen M482_69 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) M482_691 ENOG4105C37 (CBS) domain M482_692 ENOG41061GZ Protein of unknown function (DUF1107) M482_693 ENOG4108UUE Transcriptional regulator M482_694 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase M482_695 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic M482_697 ENOG4108V1T peptidylprolyl cis-trans isomerase M482_698 ENOG4105FHY Opacity-associated protein A M482_70 ENOG4107FB0 transcriptional regulator DeoR family M482_700 ENOG4108RS6 transposase M482_702 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) M482_705 ENOG4108MXZ Esterase M482_71 ENOG4105C44 Serine transporter M482_710 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase M482_711 ENOG4105D4A Cell wall formation (By similarity) M482_717 ENOG4108RR8 protoporphyrinogen oxidase M482_718 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) M482_719 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein M482_72 ENOG4105DZ1 carboxypeptidase M482_723 ENOG4107QK7 reductase M482_725 ENOG4105MDZ Transcriptional activator rfaH M482_726 ENOG4105D52 delta-aminolevulinic acid dehydratase M482_728 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) M482_73 ENOG4108UMI ABC transporter, permease M482_730 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) M482_732 ENOG4105JC1 sterol-binding domain protein M482_734 ENOG4105CGY Dna recombination protein M482_735 ENOG4108KF1 Membrane M482_738 ENOG4108I5U Uridine phosphorylase M482_739 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) M482_741 ENOG4105EMK carboxylate amino acid amine transporter M482_742 ENOG4105DZ2 Transcriptional regulator M482_743 ENOG4105RK9 auxin efflux carrier M482_744 ENOG4107T6V glycerophosphoryl diester phosphodiesterase M482_75 ENOG4105D01 (LipO)protein M482_756 ENOG4108IV0 ABC, transporter M482_757 ENOG4105C0Z ABC transporter M482_758 ENOG4105CF8 branched-chain amino acid ABC transporter, permease M482_759 ENOG4105C32 Amino acid ABC transporter (Permease) M482_760 ENOG4105CP9 extracellular ligand-binding receptor M482_761 ENOG4105U59 -acetyltransferase M482_762 ENOG4108RS6 transposase M482_764 ENOG4105CRP Part of the ABC transporter FtsEX involved in M482_765 ENOG4105CAK Cell division ATP-binding protein ftsE M482_766 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) M482_766 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) M482_767 ENOG4106H78 methyltransferase M482_768 ENOG4105MG3 Membrane M482_771 ENOG4107FS9 Membrane M482_774 ENOG4105EX9 Membrane M482_775 ENOG4108W1V Lipoprotein M482_776 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) M482_778 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A M482_779 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase M482_78 ENOG4108TGY Glutathione S-transferase M482_781 ENOG4105DQF Hydrolase M482_782 ENOG4108EUD Lysophospholipase M482_784 ENOG4105CCF Lysine exporter protein (Lyse ygga) M482_785 ENOG4105C9U ATP-dependent DNA helicase RecQ M482_786 ENOG4105HDD phospholipase M482_787 ENOG4108VUY thioesterase Superfamily protein M482_788 ENOG4105FR1 rard protein M482_789 ENOG4107QUT magnesium and cobalt transport protein CorA M482_79 ENOG4105D05 Receptor M482_791 ENOG4105EQN UPF0261 protein M482_793 ENOG4105C4R Atp-dependent dna helicase M482_794 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant M482_795 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) M482_796 ENOG4105CT0 Protein of unknown function, DUF484 M482_798 ENOG4105S7Z (LipO)protein M482_8 ENOG4105EUR Domain-Containing protein M482_8 ENOG4105EUR Domain-Containing protein M482_800 ENOG4107T0K Adenylate cyclase M482_802 ENOG41076E6 Uroporphyrinogen-III Synthase M482_803 ENOG4105ECF c-methyltransferase M482_804 ENOG410601J HemY protein M482_81 ENOG4105EHG Permease protein M482_811 ENOG4105C85 amino acid M482_815 ENOG4105EGZ biosynthesis protein M482_816 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase M482_817 ENOG4108WJ1 acetyltransferase M482_818 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) M482_819 ENOG4105C1B dTDP-glucose 4-6-dehydratase M482_820 ENOG4108IJ1 Dehydrogenase M482_821 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase M482_822 ENOG4105SFE lipopolysaccharide biosynthesis protein M482_823 ENOG4105ESV Glycosyl transferase, family 4 M482_825 ENOG4105K63 Thioredoxin M482_828 ENOG4105C4R Atp-dependent dna helicase M482_829 ENOG4105KQ5 peptidylprolyl cis-trans isomerase M482_832 ENOG4105GQR Chaperone M482_833 ENOG4105CW0 outer membrane usher protein M482_835 ENOG4108VEV chaperone M482_84 ENOG4108IQI permease M482_842 ENOG4105EMY transcriptional regulator M482_848 ENOG4105C7B Threonine dehydratase M482_850 ENOG4105CM2 brancheD-chain amino acid aminotransferase M482_851 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit M482_853 ENOG4105C0P Mg chelatase subunit ChlI M482_854 ENOG4108WFC UPF0438 protein yifE M482_855 ENOG41062B0 ABC transporter, permease M482_857 ENOG4107R9N ABC transporter M482_858 ENOG4105C2J ABC transporter M482_859 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator M482_86 ENOG4105DUM transcriptional regulator, lysR family M482_869 ENOG4105C12 Phosphoribosylglycinamide synthetase M482_87 ENOG4105HMI Membrane M482_870 ENOG4108T8B Protein of unknown function (DUF1481) M482_872 ENOG4105R2J Conserved Protein M482_873 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) M482_878 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) M482_880 ENOG4105D06 uba thif-type nad fad binding protein M482_884 ENOG4105D41 biosynthesis protein thiH M482_885 ENOG4105D41 biosynthesis protein thiH M482_89 ENOG4108D1K outer membrane usher protein M482_893 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) M482_894 ENOG4105PM1 preprotein translocase subunit SecE M482_9 ENOG4105HDK L-asparaginase M482_90 ENOG4108UIF Chaperone M482_904 ENOG4105C85 amino acid M482_905 ENOG4105C84 Histidine ammonia-lyase M482_907 ENOG4105C6T cysteine synthase M482_913 ENOG4105CM4 permease protein M482_915 ENOG4108IPW abc transporter atp-binding protein M482_920 ENOG4105ZTC transcriptional activator, Ogr delta M482_922 ENOG4105DFP Integrase M482_924 ENOG4105T16 Transcriptional regulator (AraC family) M482_925 ENOG4107RNG ABC transporter M482_927 ENOG4105DFW ABC transporter M482_929 ENOG4105CMG Carbohydrate kinase M482_93 ENOG4108SGD regulatory protein M482_931 ENOG4108TTM chaperone M482_934 ENOG4106EAR Fimbrial protein M482_935 ENOG4105MEV Acyl-transferase M482_937 ENOG4105DQ6 Transposase M482_938 ENOG4105SYT Methylenetetrahydrofolate reductase M482_939 ENOG4105CFH Aspartokinase M482_94 ENOG4105DM4 PTS System M482_940 ENOG4105C28 cystathionine M482_942 ENOG4108Z12 YiaAB two helix domain-containing protein M482_944 ENOG4105C25 Primosomal protein n' M482_946 ENOG4105ETE Transcriptional regulator (LacI family M482_947 ENOG4105ETE Transcriptional regulator (LacI family M482_948 ENOG41063M6 Cell Division Protein M482_95 ENOG4105DE4 1-phosphofructokinase M482_951 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase M482_955 ENOG4108MBX Secretion Protein M482_956 ENOG4108JJA ABC, transporter M482_959 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) M482_96 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein M482_960 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) M482_961 ENOG4105CBT Fructose-1,6-bisphosphatase M482_962 ENOG4105DP0 ferredoxin-NADP reductase M482_963 ENOG4108VTS Membrane M482_964 ENOG4105EBK exported protein M482_966 ENOG4107F9Y LysR family transcriptional regulator M482_968 ENOG4105JSC dimethylmenaquinone methyltransferase M482_969 ENOG4107QPK )-transporter M482_970 ENOG4107QPK )-transporter M482_972 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein M482_977 ENOG4105FMW periplasmic M482_978 ENOG4105E3W Two component transcriptional regulator (Winged helix family M482_979 ENOG4105E0F Histidine kinase M482_98 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane M482_980 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) M482_981 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) M482_982 ENOG4105D7W serine acetyltransferase M482_985 ENOG4105VW4 glutaredoxin 3 M482_986 ENOG4107YZP Rhodanese domain protein M482_988 ENOG41063SB peptidase M482_989 ENOG4105PXI polysaccharide deacetylase M482_99 ENOG4105C2J ABC transporter M482_990 ENOG4105PXI polysaccharide deacetylase M482_992 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) M482_994 ENOG4105XA0 heptosyltransferase ii M482_995 ENOG4105D16 lipopolysaccharide heptosyltransferase i M482_996 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase