locus-tag	class	description
M482_10	COG1944	ATP diphosphatase activity
M482_1000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M482_1003	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M482_1008	COG1561	YicC-like family, N-terminal region
M482_1009	COG2860	membrane
M482_101	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M482_1010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M482_1012	COG1758	RNA polymerase activity
M482_1013	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M482_1014	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M482_1015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M482_1016	COG0786	glutamate:sodium symporter activity
M482_1017	COG2233	PERMEase
M482_1018	COG2982	Protein involved in outer membrane biogenesis
M482_1019	COG0456	acetyltransferase
M482_1023	COG1295	ribonuclease BN
M482_1024	COG1011	Hydrolase
M482_1026	COG0174	glutamine synthetase
M482_1027	COG3852	Histidine kinase
M482_1029	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M482_1032	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M482_1032	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M482_1033	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M482_1034	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M482_1035	COG3084	Protein conserved in bacteria
M482_1037	COG1763	Mo-molybdopterin cofactor biosynthetic process
M482_1038	COG3328	transposase activity
M482_1043	COG2186	Transcriptional regulator
M482_1045	COG0477	Major facilitator Superfamily
M482_1046	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M482_1047	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M482_1053	COG1522	sequence-specific DNA binding
M482_1054	COG0716	FMN binding
M482_1057	COG3312	ion transport
M482_106	COG1028	Short-chain dehydrogenase reductase Sdr
M482_1067	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M482_1069	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M482_1070	COG0573	inorganic phosphate transmembrane transporter activity
M482_1071	COG0581	inorganic phosphate transmembrane transporter activity
M482_1073	COG0704	Plays a role in the regulation of phosphate uptake
M482_1075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M482_1076	COG0765	amino acid transport
M482_1077	COG0765	amino acid transport
M482_1078	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M482_1079	COG2252	PERMEase
M482_1084	COG0706	membrane insertase activity
M482_1087	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M482_1090	COG0592	DNA-directed DNA polymerase activity
M482_1091	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
M482_1092	COG0187	DNA topoisomerase II activity
M482_1093	COG0561	phosphatase activity
M482_1094	COG2801	Transposase and inactivated derivatives
M482_1096	COG2423	ornithine cyclodeaminase activity
M482_1097	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M482_1098	COG0823	Involved in the tonB-independent uptake of proteins
M482_1099	COG0823	Involved in the tonB-independent uptake of proteins
M482_11	COG2116	formate transmembrane transporter activity
M482_110	COG1312	Catalyzes the dehydration of D-mannonate
M482_1100	COG5645	(Lipo)protein
M482_1104	COG3977	Valine--pyruvate aminotransferase
M482_1106	COG0366	Alpha amylase catalytic
M482_1109	COG2885	chlorophyll binding
M482_111	COG0246	Mannitol dehydrogenase
M482_1111	COG2818	Glycosylase
M482_1116	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_1116	COG2213	PTS system mannitol-specific
M482_1118	COG3722	fumarate hydratase activity
M482_112	COG2186	Transcriptional regulator
M482_1125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M482_1127	COG3383	formate dehydrogenase (NAD+) activity
M482_1127	COG0243	molybdopterin cofactor binding
M482_1128	COG3383	formate dehydrogenase (NAD+) activity
M482_1128	COG0243	molybdopterin cofactor binding
M482_1129	COG0437	4 iron, 4 sulfur cluster binding
M482_1130	COG2864	formate dehydrogenase
M482_1133	COG3276	selenocysteine insertion sequence binding
M482_1135	COG3328	transposase activity
M482_114	COG0523	cobalamin synthesis protein
M482_1140	COG2801	Transposase and inactivated derivatives
M482_1142	COG1349	DNA-binding transcription factor activity
M482_1146	COG0058	SHG alpha-glucan phosphorylase activity
M482_1147	COG1640	4-alpha-glucanotransferase
M482_115	COG0671	phosphoesterase, PA-phosphatase related
M482_1154	COG1918	ferrous iron import across plasma membrane
M482_1155	COG2183	response to ionizing radiation
M482_1156	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M482_1157	COG0745	RESPONSE REGULATOR receiver
M482_116	COG0791	NLP P60 protein
M482_1161	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M482_1162	COG1011	Hydrolase
M482_1165	COG0494	nUDIX hydrolase
M482_1166	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M482_1171	COG4796	Type ii and iii secretion system protein
M482_1176	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M482_1177	COG0546	phosphoglycolate phosphatase activity
M482_1178	COG0180	Tryptophanyl-tRNA synthetase
M482_118	COG2200	EAL domain
M482_1181	COG2146	nitrite reductase [NAD(P)H] activity
M482_1182	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M482_1183	COG0402	S-adenosylhomocysteine deaminase activity
M482_1187	COG1486	melibiose metabolic process
M482_1188	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M482_1189	COG0433	COG0433 Predicted ATPase
M482_119	COG4166	transmembrane transport
M482_1192	COG1289	transmembrane transporter activity
M482_1194	COG1765	OsmC-like protein
M482_1196	COG3954	Phosphoribulokinase
M482_1198	COG0429	hydrolase of the alpha beta-hydrolase fold
M482_12	COG1882	Formate acetyltransferase
M482_120	COG4174	ABC transporter (Permease)
M482_1200	COG4521	taurine ABC transporter
M482_1202	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M482_1203	COG2175	clavaminate synthase activity
M482_1206	COG1216	Glycosyl transferase, family 2
M482_1207	COG0488	(ABC) transporter
M482_121	COG4239	(ABC) transporter, permease
M482_1210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M482_1211	COG1047	Peptidyl-prolyl cis-trans
M482_1213	COG0545	Peptidyl-prolyl cis-trans isomerase
M482_1214	COG2964	Protein conserved in bacteria
M482_1219	COG0049	tRNA binding
M482_122	COG4172	Belongs to the ABC transporter superfamily
M482_1222	COG1943	Transposase
M482_1225	COG0051	transcription antitermination factor activity, RNA binding
M482_1230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
M482_1232	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
M482_1233	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M482_1235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M482_1236	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M482_124	COG2814	Major facilitator Superfamily
M482_1244	COG1841	ribosomal large subunit assembly
M482_1246	COG0201	protein transport
M482_1247	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M482_125	COG1187	pseudouridine synthase activity
M482_1250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M482_1253	COG0789	Transcriptional regulator
M482_1254	COG3036	rescue of stalled ribosome
M482_1256	COG0569	domain protein
M482_126	COG1061	Type III restriction enzyme res subunit
M482_1260	COG0758	DNA mediated transformation
M482_1262	COG0551	DNA topoisomerase type I activity
M482_1265	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M482_1272	COG2801	Transposase and inactivated derivatives
M482_1279	COG3162	membrane
M482_128	COG1943	Transposase
M482_1281	COG1301	dicarboxylic acid transport
M482_130	COG3082	Protein of unknown function (DUF1414)
M482_1303	COG2391	methyltransferase activity
M482_1304	COG0425	Belongs to the sulfur carrier protein TusA family
M482_1305	COG0583	DNA-binding transcription factor activity
M482_1306	COG0814	amino acid
M482_1307	COG0626	cystathionine gamma-synthase activity
M482_1309	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M482_131	COG3083	sulfuric ester hydrolase activity
M482_1310	COG4558	Periplasmic binding protein
M482_1311	COG3720	iron ion transport
M482_1312	COG4771	TonB-dependent receptor
M482_1314	COG0702	epimerase
M482_1315	COG3721	Heme iron utilization protein
M482_1320	COG1358	cellular component organization or biogenesis
M482_1332	COG3121	Chaperone
M482_134	COG3157	Type VI secretion system effector, Hcp
M482_1341	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M482_1343	COG0735	belongs to the Fur family
M482_1344	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M482_1347	COG0305	Participates in initiation and elongation during chromosome replication
M482_1348	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M482_1349	COG1448	Aminotransferase
M482_1350	COG2315	Protein conserved in bacteria
M482_1351	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M482_1352	COG0629	single-stranded DNA binding
M482_1354	COG1454	alcohol dehydrogenase
M482_1368	COG1309	transcriptional regulator
M482_1369	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M482_1369	COG0493	'glutamate synthase
M482_1370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M482_1371	COG3383	formate dehydrogenase (NAD+) activity
M482_1374	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M482_138	COG2723	6-phospho-beta-galactosidase activity
M482_1382	COG2076	Multidrug Resistance protein
M482_1383	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
M482_1385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M482_1386	COG1053	succinate dehydrogenase
M482_1388	COG1511	domain protein
M482_1388	COG3264	Mechanosensitive ion channel
M482_1391	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M482_1394	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M482_1395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M482_1395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M482_1396	COG0802	atpase or kinase
M482_1397	COG0860	N-Acetylmuramoyl-L-alanine amidase
M482_14	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M482_140	COG1737	Transcriptional regulator
M482_1401	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M482_1402	COG0330	HflC and HflK could
M482_1403	COG0330	HflC and HflK could
M482_1404	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
M482_1407	COG0557	exoribonuclease II activity
M482_1408	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M482_1409	COG1960	acyl-CoA dehydrogenase activity
M482_1410	COG3650	response to hydrogen peroxide
M482_1413	COG2194	sulfuric ester hydrolase activity
M482_1414	COG2197	response regulator
M482_1415	COG3851	Histidine kinase
M482_1416	COG2271	Major facilitator Superfamily
M482_1420	COG2831	hemolysin activation secretion protein
M482_1422	COG0747	negative chemotaxis
M482_1423	COG0601	transmembrane transport
M482_1424	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M482_1425	COG0444	Belongs to the ABC transporter superfamily
M482_1426	COG4608	Belongs to the ABC transporter superfamily
M482_1427	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M482_1428	COG2200	EAL domain
M482_1428	COG2199	diguanylate cyclase activity
M482_1429	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M482_1434	COG0612	Peptidase, M16
M482_1435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M482_1436	COG1942	4-Oxalocrotonate Tautomerase
M482_1437	COG2200	EAL domain
M482_1438	COG2982	Protein involved in outer membrane biogenesis
M482_1439	COG2134	cdp-diacylglycerol pyrophosphatase
M482_144	COG3299	homolog of phage Mu protein gp47
M482_1440	COG1295	ribonuclease BN
M482_1445	COG1929	Belongs to the glycerate kinase type-1 family
M482_1446	COG2610	gluconate transmembrane transporter activity
M482_1447	COG3835	regulator
M482_1448	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M482_1449	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M482_1450	COG0339	signal peptide processing
M482_1454	COG0589	response to stress
M482_1457	COG0306	phosphate transporter
M482_1458	COG2081	HI0933 family
M482_1461	COG1943	Transposase
M482_1463	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_1464	COG1879	ABC-type sugar transport system periplasmic component
M482_1466	COG0191	fructose-bisphosphate aldolase activity
M482_1468	COG0745	RESPONSE REGULATOR receiver
M482_1470	COG1741	Belongs to the pirin family
M482_1471	COG1609	Transcriptional regulator
M482_1472	COG1609	Transcriptional regulator
M482_1473	COG2610	gluconate transmembrane transporter activity
M482_1474	COG3265	gluconokinase activity
M482_1478	COG2095	MarC family integral membrane protein
M482_1479	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M482_1485	COG3275	phosphorelay sensor kinase activity
M482_1488	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M482_1490	COG0058	SHG alpha-glucan phosphorylase activity
M482_1491	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M482_1494	COG2801	Transposase and inactivated derivatives
M482_1498	COG0513	Belongs to the DEAD box helicase family
M482_15	COG2814	Major facilitator Superfamily
M482_1501	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M482_1504	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M482_1509	COG3153	acetyltransferase
M482_1513	COG1653	transport
M482_1515	COG0395	ABC-type sugar transport system, permease component
M482_1516	COG3842	ATPase activity
M482_1519	COG0702	epimerase
M482_1520	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M482_1521	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
M482_1522	COG3454	Phosphonate metabolism
M482_1523	COG4778	phosphonate C-P lyase system protein PhnL
M482_1524	COG4107	phosphonate C-P lyase system protein PhnK
M482_1525	COG3627	carbon phosphorus lyase activity
M482_1526	COG3626	phosphonate metabolism
M482_1527	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
M482_1528	COG3624	Phosphonate C-P lyase system protein PhnG
M482_1529	COG2188	Transcriptional regulator
M482_153	COG4386	tail sheath protein
M482_1533	COG4608	Belongs to the ABC transporter superfamily
M482_1534	COG0444	Belongs to the ABC transporter superfamily
M482_1535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M482_1536	COG0601	transmembrane transport
M482_1539	COG2731	YhcH YjgK YiaL family protein
M482_1540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M482_1541	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
M482_1543	COG0525	valine-tRNA ligase activity
M482_1544	COG2927	DNA polymerase III (CHI subunit)
M482_1546	COG0795	lipopolysaccharide-transporting ATPase activity
M482_1547	COG0795	lipopolysaccharide-transporting ATPase activity
M482_1549	COG0582	viral genome integration into host DNA
M482_1554	COG1401	restriction endodeoxyribonuclease activity
M482_1556	COG2963	transposase activity
M482_1566	COG4269	membrane
M482_1568	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M482_1569	COG2207	Transcriptional regulator
M482_157	COG3622	Belongs to the hyi family
M482_1570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M482_1571	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M482_1572	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_1572	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M482_1572	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_158	COG1349	DNA-binding transcription factor activity
M482_1580	COG2390	Transcriptional regulator
M482_1582	COG0859	PFAM glycosyl transferase family 9
M482_1585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M482_1586	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M482_1589	COG3706	GGDEF domain
M482_159	COG0235	Class ii aldolase
M482_1593	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
M482_1594	COG0456	acetyltransferase
M482_1596	COG2823	Periplasmic or secreted lipoprotein
M482_1598	COG4667	esterase of the alpha-beta hydrolase superfamily
M482_1599	COG0084	hydrolase, TatD family'
M482_160	COG3395	kinase activity
M482_1600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M482_1601	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M482_1605	COG3726	membrane protein affecting hemolysin expression
M482_1606	COG0560	Phosphoserine phosphatase
M482_1611	COG0488	(ABC) transporter
M482_1612	COG2885	chlorophyll binding
M482_1613	COG2199	diguanylate cyclase activity
M482_1616	COG0741	lytic transglycosylase activity
M482_1618	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
M482_1619	COG2207	Transcriptional regulator
M482_1619	COG3708	Transcriptional regulator
M482_1622	COG3045	CreA protein
M482_1623	COG0745	RESPONSE REGULATOR receiver
M482_1631	COG0521	Mo-molybdopterin cofactor biosynthetic process
M482_1634	COG1584	GPR1 FUN34 yaaH family protein
M482_1638	COG0583	DNA-binding transcription factor activity
M482_1640	COG0196	riboflavin kinase activity
M482_1643	COG1047	Peptidyl-prolyl cis-trans
M482_1646	COG0505	Belongs to the CarA family
M482_1647	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M482_1648	COG1280	lysine exporter protein (LysE YggA)
M482_1649	COG2966	Psort location CytoplasmicMembrane, score
M482_1651	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M482_1656	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
M482_1657	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M482_1659	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
M482_1660	COG0564	pseudouridine synthase activity
M482_1670	COG3501	Rhs element vgr protein
M482_1677	COG3047	cAMP biosynthetic process
M482_1677	COG2885	chlorophyll binding
M482_1681	COG0417	DNA replication proofreading
M482_1682	COG0586	Pfam SNARE associated Golgi protein
M482_1684	COG1178	ABC-type Fe3 transport system permease component
M482_1685	COG4143	(ABC) transporter
M482_1688	COG2814	Major facilitator Superfamily
M482_169	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M482_1691	COG0473	3-isopropylmalate dehydrogenase activity
M482_1695	COG1022	Amp-dependent synthetase and ligase
M482_1696	COG3328	transposase activity
M482_1697	COG0028	Belongs to the TPP enzyme family
M482_1699	COG1943	Transposase
M482_17	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M482_1700	COG1609	Transcriptional regulator
M482_1705	COG3116	cell division
M482_1706	COG0768	penicillin binding
M482_1707	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M482_1708	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M482_1711	COG0772	Belongs to the SEDS family
M482_1715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M482_1716	COG0849	cell division
M482_1717	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M482_172	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
M482_1722	COG0494	nUDIX hydrolase
M482_1728	COG0237	dephospho-CoA kinase activity
M482_1730	COG1459	type II secretion system
M482_1731	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M482_1732	COG4969	Belongs to the N-Me-Phe pilin family
M482_1734	COG3023	N-Acetylmuramoyl-L-alanine amidase
M482_1735	COG3725	Membrane protein required for beta-lactamase induction
M482_1736	COG1113	amino acid transport
M482_1737	COG2186	Transcriptional regulator
M482_1738	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
M482_1739	COG0508	dehydrogenase complex catalyzes the overall conversion of
M482_174	COG2223	nitrite transmembrane transporter activity
M482_1740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M482_1741	COG1943	Transposase
M482_1742	COG1049	propionate catabolic process, 2-methylcitrate cycle
M482_1744	COG0697	spore germination
M482_1748	COG2132	Multicopper oxidase
M482_1749	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M482_175	COG2223	nitrite transmembrane transporter activity
M482_1750	COG0288	reversible hydration of carbon dioxide
M482_1751	COG1131	(ABC) transporter
M482_1752	COG0842	Transport permease protein
M482_1754	COG0726	polysaccharide deacetylase
M482_1758	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M482_1759	COG0617	tRNA 3'-terminal CCA addition
M482_176	COG0642	Histidine kinase
M482_176	COG2198	Histidine kinase
M482_1760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M482_1761	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M482_1763	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M482_1764	COG1643	Atp-dependent helicase
M482_1765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M482_1766	COG1120	ATPase activity
M482_1767	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M482_1768	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M482_177	COG2198	Histidine kinase
M482_177	COG0642	Histidine kinase
M482_1772	COG2860	membrane
M482_1774	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M482_1776	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M482_1777	COG3437	response regulator, receiver
M482_1777	COG4999	Histidine kinase
M482_1777	COG3850	Histidine kinase
M482_1777	COG2205	protein histidine kinase activity
M482_1778	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M482_1779	COG3956	TIGRFAM MazG family protein
M482_1783	COG0602	queuosine metabolic process
M482_1784	COG0720	synthase
M482_179	COG2205	protein histidine kinase activity
M482_179	COG0784	Response regulator, receiver
M482_1795	COG0529	Catalyzes the synthesis of activated sulfate
M482_1798	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M482_1803	COG4942	peptidase
M482_1803	COG1388	LysM domain
M482_1804	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M482_1805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
M482_1806	COG0698	ribose 5-phosphate isomerase
M482_1807	COG1063	alcohol dehydrogenase
M482_1808	COG1028	Short-chain dehydrogenase reductase Sdr
M482_1809	COG2376	Dihydroxyacetone kinase
M482_1812	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M482_1816	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M482_1817	COG1858	cytochrome C peroxidase
M482_1819	COG4771	TonB-dependent receptor
M482_1821	COG0024	Methionine aminopeptidase
M482_1823	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M482_1823	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M482_1824	COG1070	Carbohydrate kinase
M482_1825	COG3623	hexulose-6-phosphate isomerase
M482_1826	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_1827	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_1828	COG1129	ABC transporter
M482_1830	COG1349	DNA-binding transcription factor activity
M482_1831	COG0235	Class ii aldolase
M482_1832	COG0243	molybdopterin cofactor binding
M482_1833	COG0437	4 iron, 4 sulfur cluster binding
M482_1834	COG3302	dmso reductase anchor subunit
M482_1835	COG3381	protein complex oligomerization
M482_1836	COG3038	cytochrome b561
M482_1837	COG3783	Cytochrome b(562)
M482_184	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M482_1841	COG1129	ABC transporter
M482_1842	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_1843	COG3959	Transketolase, thiamine diphosphate binding domain
M482_1844	COG3958	Transketolase
M482_1845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M482_1852	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M482_1853	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
M482_1857	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M482_1858	COG1238	metal cluster binding
M482_1859	COG2918	glutathione biosynthetic process
M482_1861	COG4536	flavin adenine dinucleotide binding
M482_1862	COG4137	Cytochrome C assembly protein
M482_1863	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M482_1868	COG3137	Salt-induced outer membrane protein
M482_1869	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M482_187	COG0814	amino acid
M482_1870	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M482_1871	COG3279	Response regulator of the LytR AlgR family
M482_1872	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M482_1875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M482_1876	COG0287	Prephenate dehydrogenase
M482_1876	COG1605	Chorismate mutase
M482_1878	COG1605	Chorismate mutase
M482_1878	COG0077	Prephenate dehydratase
M482_1879	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M482_1880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M482_1881	COG0564	pseudouridine synthase activity
M482_1883	COG0542	response to heat
M482_1894	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M482_1895	COG2224	Isocitrate lyase
M482_1897	COG1414	Transcriptional regulator
M482_1902	COG0527	aspartate kinase activity
M482_1905	COG3833	ABC-type maltose transport systems, permease component
M482_1906	COG1175	transmembrane transport
M482_1917	COG2801	Transposase and inactivated derivatives
M482_192	COG0697	spore germination
M482_1933	COG3501	Rhs element vgr protein
M482_1936	COG3209	COG3209 Rhs family protein
M482_194	COG1982	Orn Lys Arg decarboxylase major
M482_1942	COG3501	Rhs element vgr protein
M482_1944	COG3209	COG3209 Rhs family protein
M482_1947	COG0673	inositol 2-dehydrogenase activity
M482_1948	COG2207	Transcriptional regulator
M482_1948	COG1917	Cupin 2, conserved barrel domain protein
M482_1949	COG1869	D-ribose catabolic process
M482_195	COG3328	transposase activity
M482_1950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M482_1952	COG0431	NADPH-dependent FMN reductase
M482_1953	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M482_1955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M482_1957	COG3077	Addiction module antitoxin, RelB DinJ family
M482_1958	COG2252	PERMEase
M482_1959	COG0025	NhaP-type Na H and K H
M482_196	COG1982	Orn Lys Arg decarboxylase major
M482_1961	COG1560	Kdo2-lipid A biosynthetic process
M482_1963	COG1129	ABC transporter
M482_1964	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_1966	COG1069	ribulokinase activity
M482_1968	COG0625	glutathione transferase activity
M482_197	COG0531	amino acid
M482_1971	COG1943	Transposase
M482_1972	COG1278	Cold shock
M482_1973	COG1278	Cold shock
M482_1974	COG3133	Outer membrane lipoprotein
M482_1975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M482_1977	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M482_198	COG1174	glycine betaine transport
M482_1981	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M482_1982	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M482_1984	COG4145	pantothenate transmembrane transporter activity
M482_1985	COG3924	membrane
M482_1987	COG0439	Biotin carboxylase
M482_1988	COG0511	ligase activity, forming carbon-carbon bonds
M482_199	COG1125	glycine betaine transport
M482_1991	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M482_1992	COG0604	alcohol dehydrogenase
M482_1993	COG2200	EAL domain
M482_1993	COG2199	diguanylate cyclase activity
M482_1994	COG1077	Cell shape determining protein MreB Mrl
M482_1995	COG1792	Involved in formation and maintenance of cell shape
M482_1996	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M482_1998	COG1530	ribonuclease E activity
M482_1999	COG3164	Protein of unknown function
M482_20	COG3107	peptidoglycan biosynthetic process
M482_20	COG1674	ftsk spoiiie
M482_200	COG1174	glycine betaine transport
M482_2000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M482_2001	COG0312	modulator of DNA gyrase
M482_201	COG1732	Glycine betaine
M482_2011	COG0583	DNA-binding transcription factor activity
M482_2015	COG1012	belongs to the aldehyde dehydrogenase family
M482_2018	COG2732	(Barnase) inhibitor
M482_202	COG2897	thiosulfate sulfurtransferase activity
M482_2020	COG0312	modulator of DNA gyrase
M482_2022	COG3783	Cytochrome b(562)
M482_2023	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M482_2024	COG0366	Alpha amylase catalytic
M482_2025	COG1263	PTS System
M482_2025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M482_2031	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_2033	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_2035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M482_2036	COG1137	ATPase activity
M482_2037	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M482_2038	COG3117	lipopolysaccharide transmembrane transporter activity
M482_2039	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M482_2040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M482_2040	COG0517	IMP dehydrogenase activity
M482_2041	COG0530	calcium, potassium:sodium antiporter activity
M482_2042	COG1127	ABC transporter
M482_2043	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M482_2044	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M482_2045	COG2854	intermembrane phospholipid transfer
M482_2046	COG3113	response to antibiotic
M482_2047	COG5007	Belongs to the BolA IbaG family
M482_2049	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M482_205	COG0410	ABC transporter
M482_2050	COG1943	Transposase
M482_2051	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M482_2052	COG3105	Protein conserved in bacteria
M482_2053	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M482_2056	COG0625	glutathione transferase activity
M482_2057	COG2969	positive regulation of protein catabolic process
M482_2059	COG0493	'glutamate synthase
M482_206	COG1122	ATPase activity
M482_2060	COG0069	glutamate synthase activity
M482_2060	COG0070	glutamate synthase
M482_2060	COG0067	glutamate synthase
M482_2061	COG1242	4 iron, 4 sulfur cluster binding
M482_2062	COG2198	Histidine kinase
M482_2062	COG0784	Response regulator, receiver
M482_2062	COG5002	protein histidine kinase activity
M482_2063	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
M482_2065	COG2823	Periplasmic or secreted lipoprotein
M482_2069	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M482_2070	COG1741	Belongs to the pirin family
M482_2071	COG0583	DNA-binding transcription factor activity
M482_2072	COG0435	Glutathione S-transferase
M482_2073	COG2259	Doxx family
M482_2075	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
M482_2076	COG4575	ribosome binding
M482_2079	COG0586	Pfam SNARE associated Golgi protein
M482_2082	COG2271	Major facilitator Superfamily
M482_2083	COG2271	Major facilitator Superfamily
M482_2085	COG0246	Mannitol dehydrogenase
M482_2086	COG2721	sulfolactate sulfo-lyase activity
M482_2088	COG1943	Transposase
M482_2090	COG0673	inositol 2-dehydrogenase activity
M482_2091	COG1451	nucleotide metabolic process
M482_2094	COG1902	pentaerythritol trinitrate reductase activity
M482_2094	COG0446	pyridine nucleotide-disulphide oxidoreductase
M482_2095	COG3247	response to pH
M482_2098	COG4245	von Willebrand factor, type A
M482_210	COG4807	Protein conserved in bacteria
M482_2101	COG4245	von Willebrand factor, type A
M482_2102	COG2831	hemolysin activation secretion protein
M482_2103	COG3210	domain, Protein
M482_2105	COG3210	domain, Protein
M482_2107	COG3210	domain, Protein
M482_2111	COG3842	ATPase activity
M482_2112	COG3459	Glycosyltransferase 36 associated
M482_2113	COG1609	Transcriptional regulator
M482_2114	COG1653	transport
M482_2116	COG0395	ABC-type sugar transport system, permease component
M482_2120	COG1289	transmembrane transporter activity
M482_2128	COG0251	oxidation-reduction process
M482_213	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
M482_2145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M482_2146	COG0358	DNA primase activity
M482_215	COG2261	transglycosylase associated protein
M482_2150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M482_2153	COG4991	sh3 domain protein
M482_2154	COG3025	triphosphatase activity
M482_2157	COG0531	amino acid
M482_2161	COG3384	dioxygenase
M482_2162	COG0754	glutathionylspermidine amidase activity
M482_2165	COG1538	Outer membrane efflux protein
M482_2166	COG0494	nUDIX hydrolase
M482_2167	COG3151	Protein conserved in bacteria
M482_2168	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M482_2169	COG3150	esterase
M482_217	COG1403	HNH endonuclease
M482_2170	COG0187	DNA topoisomerase II activity
M482_2171	COG0583	DNA-binding transcription factor activity
M482_2172	COG2249	NAD(P)H dehydrogenase (quinone) activity
M482_2173	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M482_2174	COG0204	Acyl-transferase
M482_2175	COG2132	Multicopper oxidase
M482_2178	COG0656	L-ascorbic acid biosynthetic process
M482_2179	COG1979	alcohol dehydrogenase
M482_2180	COG2207	Transcriptional regulator
M482_2181	COG0586	Pfam SNARE associated Golgi protein
M482_2182	COG0626	cystathionine gamma-synthase activity
M482_2183	COG0811	peptide transport
M482_2185	COG0848	biopolymer transport protein
M482_219	COG0277	FAD linked oxidase domain protein
M482_2195	COG4964	Belongs to the GSP D family
M482_2196	COG4964	Belongs to the GSP D family
M482_22	COG0492	ferredoxin-NADP+ reductase activity
M482_220	COG1686	Belongs to the peptidase S11 family
M482_2204	COG4592	Periplasmic binding protein
M482_2208	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M482_2209	COG1684	flagellar biosynthetic protein fliR
M482_2210	COG1987	bacterial-type flagellum assembly
M482_2214	COG2204	response regulator
M482_222	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M482_2223	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
M482_2224	COG1815	bacterial-type flagellum-dependent cell motility
M482_2225	COG1558	bacterial-type flagellum-dependent cell motility
M482_2226	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M482_2227	COG1749	Flagellar hook protein flgE
M482_2228	COG4787	bacterial-type flagellum-dependent cell motility
M482_2229	COG4786	Flagellar basal body rod
M482_2230	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
M482_2231	COG1706	bacterial-type flagellum-dependent cell motility
M482_2233	COG1256	bacterial-type flagellum assembly
M482_2237	COG3710	Transcriptional regulator
M482_2242	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M482_2247	COG1191	sigma factor activity
M482_2248	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M482_225	COG2211	Major facilitator Superfamily
M482_2253	COG3133	Outer membrane lipoprotein
M482_2256	COG2801	Transposase and inactivated derivatives
M482_2257	COG2211	Major facilitator Superfamily
M482_226	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M482_2267	COG3916	Acyl-homoserine-lactone synthase
M482_2268	COG2771	luxR family
M482_228	COG0583	DNA-binding transcription factor activity
M482_2286	COG1662	PFAM IS1 transposase
M482_229	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M482_2290	COG1982	Orn Lys Arg decarboxylase major
M482_2291	COG1879	ABC-type sugar transport system periplasmic component
M482_2292	COG1129	ABC transporter
M482_2293	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_2294	COG4774	siderophore transport
M482_2298	COG1194	a g-specific adenine glycosylase
M482_2300	COG3171	Protein conserved in bacteria
M482_2301	COG2066	Belongs to the glutaminase family
M482_2304	COG3064	Membrane
M482_2304	COG1073	alpha beta
M482_2304	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
M482_2305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M482_2306	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M482_2308	COG0762	integral membrane protein
M482_2309	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M482_2310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M482_2311	COG2805	Type II/IV secretion system protein
M482_2313	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M482_2316	COG0189	ligase activity
M482_2317	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M482_2318	COG2356	endonuclease I
M482_2322	COG1166	arginine decarboxylase activity
M482_2324	COG0501	Belongs to the peptidase M48B family
M482_2325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M482_2329	COG0191	fructose-bisphosphate aldolase activity
M482_233	COG1943	Transposase
M482_2334	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M482_2335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M482_2336	COG1943	Transposase
M482_2337	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M482_234	COG0670	Belongs to the BI1 family
M482_2340	COG0006	proline dipeptidase activity
M482_2341	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M482_2342	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M482_2348	COG5295	Hep Hag repeat protein
M482_235	COG0314	molybdopterin synthase activity
M482_2350	COG1272	protein, Hemolysin III
M482_2353	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M482_2354	COG0745	RESPONSE REGULATOR receiver
M482_2355	COG2205	protein histidine kinase activity
M482_2356	COG4452	Inner membrane protein CreD
M482_2357	COG0716	FMN binding
M482_2358	COG4974	Belongs to the 'phage' integrase family
M482_2359	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M482_236	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M482_2360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M482_2364	COG0582	viral genome integration into host DNA
M482_2369	COG2944	sequence-specific DNA binding
M482_238	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M482_2386	COG1695	Transcriptional regulator
M482_2387	COG0791	NLP P60 protein
M482_2389	COG1879	ABC-type sugar transport system periplasmic component
M482_2390	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_2391	COG1129	ABC transporter
M482_2393	COG2182	Extracellular solute-binding protein
M482_2394	COG1175	transmembrane transport
M482_2395	COG3833	ABC-type maltose transport systems, permease component
M482_2396	COG3867	Arabinogalactan endo-beta-1,4-galactanase
M482_2397	COG1874	Beta-galactosidase
M482_2398	COG1874	Beta-galactosidase
M482_24	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M482_240	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M482_2400	COG1263	PTS System
M482_2400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M482_2404	COG2271	Major facilitator Superfamily
M482_2408	COG0191	fructose-bisphosphate aldolase activity
M482_241	COG4628	conserved protein (DUF2132)
M482_2410	COG3119	arylsulfatase activity
M482_2411	COG0641	radical SAM
M482_2413	COG1028	Short-chain dehydrogenase reductase Sdr
M482_2415	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_2416	COG3716	PTS system mannose fructose sorbose family IID component
M482_2417	COG3715	PTS system
M482_2418	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M482_2419	COG2222	sugar isomerase
M482_242	COG0556	nucleotide-excision repair
M482_2421	COG1349	DNA-binding transcription factor activity
M482_2422	COG3119	arylsulfatase activity
M482_2430	COG0288	reversible hydration of carbon dioxide
M482_244	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
M482_2447	COG3328	transposase activity
M482_245	COG2226	methyltransferase
M482_2451	COG0840	transmembrane signaling receptor activity
M482_2453	COG0583	DNA-binding transcription factor activity
M482_2454	COG0583	DNA-binding transcription factor activity
M482_2455	COG2814	Major facilitator Superfamily
M482_2456	COG1609	Transcriptional regulator
M482_2457	COG0019	diaminopimelate decarboxylase activity
M482_2463	COG0667	Aldo Keto reductase
M482_2474	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M482_2476	COG1074	ATP-dependent DNA helicase activity
M482_2477	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M482_2481	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M482_2481	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M482_2482	COG0860	N-Acetylmuramoyl-L-alanine amidase
M482_2485	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
M482_2486	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M482_2487	COG2166	iron-sulfur cluster assembly
M482_2488	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M482_2490	COG0583	DNA-binding transcription factor activity
M482_2491	COG2363	Small membrane protein
M482_2493	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M482_2494	COG1611	Belongs to the LOG family
M482_2497	COG1943	Transposase
M482_2498	COG3098	single-species biofilm formation
M482_2499	COG0564	pseudouridine synthase activity
M482_250	COG0561	phosphatase activity
M482_2504	COG0024	Methionine aminopeptidase
M482_2510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M482_2511	COG0575	Belongs to the CDS family
M482_2512	COG0750	zinc metalloprotease
M482_2514	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
M482_2518	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M482_252	COG4149	molybdate abc transporter
M482_2520	COG0587	DNA-directed DNA polymerase activity
M482_2522	COG0346	lactoylglutathione lyase activity
M482_2523	COG0037	tRNA processing
M482_2525	COG4568	rho-dependent transcription termination
M482_2527	COG4681	YaeQ
M482_2529	COG3015	lipoprotein NlpE involved in copper resistance
M482_253	COG0725	ABC transporter, periplasmic molybdate-binding protein
M482_2531	COG1720	tRNA m6t6A37 methyltransferase activity
M482_2533	COG1464	Belongs to the NlpA lipoprotein family
M482_2534	COG2011	ABC-type metal ion transport system permease component
M482_2536	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M482_2542	COG0656	L-ascorbic acid biosynthetic process
M482_2545	COG1388	LysM domain
M482_2545	COG0741	lytic transglycosylase activity
M482_2547	COG2226	methyltransferase
M482_2549	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M482_255	COG2005	Transcriptional regulator
M482_255	COG3585	molybdate ion transport
M482_2551	COG1953	Uracil, thiamine, allantoin
M482_2553	COG2113	Glycine betaine
M482_2554	COG4176	ABC-type proline glycine betaine transport system permease component
M482_2555	COG4175	Glycine betaine
M482_2556	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M482_256	COG1119	ATPase activity
M482_2564	COG1278	Cold shock
M482_2565	COG0747	negative chemotaxis
M482_2567	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M482_2568	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
M482_2569	COG1124	(ABC) transporter
M482_2576	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
M482_2578	COG4413	Urea transporter
M482_2579	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
M482_2581	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M482_2582	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M482_2583	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M482_2584	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M482_2585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M482_2586	COG1447	Phosphotransferase system cellobiose-specific component IIA
M482_2587	COG1917	Cupin 2, conserved barrel domain protein
M482_2587	COG2169	Transcriptional regulator
M482_2591	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
M482_2592	COG0033	Phosphoglucomutase
M482_2596	COG0745	RESPONSE REGULATOR receiver
M482_2597	COG2205	protein histidine kinase activity
M482_2598	COG2205	protein histidine kinase activity
M482_26	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
M482_260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M482_2603	COG3272	Protein of unknown function (DUF1722)
M482_2605	COG5212	phosphodiesterase
M482_2606	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M482_2608	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M482_2609	COG1984	allophanate hydrolase subunit 2
M482_261	COG1085	galactose-1-phosphate uridylyltransferase
M482_2620	COG0513	Belongs to the DEAD box helicase family
M482_2622	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M482_2624	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
M482_2625	COG3026	antisigma factor binding
M482_2626	COG3086	response to oxidative stress
M482_2629	COG0681	Belongs to the peptidase S26 family
M482_2633	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M482_2635	COG1943	Transposase
M482_2636	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M482_2639	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M482_264	COG2017	converts alpha-aldose to the beta-anomer
M482_2642	COG1067	ATP-dependent peptidase activity
M482_2644	COG1943	Transposase
M482_2645	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M482_2645	COG2885	chlorophyll binding
M482_2647	COG3070	regulator of competence-specific genes
M482_2648	COG1289	transmembrane transporter activity
M482_2649	COG3304	Inner membrane component domain
M482_2650	COG0210	DNA helicase
M482_2652	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M482_2653	COG1832	CoA-binding protein
M482_2657	COG2920	part of a sulfur-relay system
M482_2664	COG1028	Short-chain dehydrogenase reductase Sdr
M482_2666	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M482_2667	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M482_2668	COG1028	Short-chain dehydrogenase reductase Sdr
M482_2669	COG3425	synthase
M482_267	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M482_2671	COG1024	Enoyl-CoA hydratase
M482_2672	COG1028	Short-chain dehydrogenase reductase Sdr
M482_2674	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M482_2675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M482_268	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M482_269	COG1230	cation diffusion facilitator family transporter
M482_2702	COG0488	(ABC) transporter
M482_2705	COG0303	'Molybdopterin
M482_2707	COG1136	(ABC) transporter
M482_2713	COG0583	DNA-binding transcription factor activity
M482_2714	COG0477	Major facilitator Superfamily
M482_2716	COG2311	Membrane
M482_2719	COG4211	Belongs to the binding-protein-dependent transport system permease family
M482_2723	COG2949	membrane
M482_2726	COG1346	cytolysis
M482_2728	COG2814	Major facilitator Superfamily
M482_2732	COG1943	Transposase
M482_2734	COG0489	protein tyrosine kinase activity
M482_2737	COG2982	Protein involved in outer membrane biogenesis
M482_2738	COG1253	flavin adenine dinucleotide binding
M482_2739	COG4114	ferric iron reductase
M482_274	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
M482_2740	COG0076	glutamate decarboxylase activity
M482_2741	COG3486	L-lysine 6-monooxygenase (NADPH) activity
M482_2744	COG1120	ATPase activity
M482_2745	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M482_2746	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M482_2747	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M482_275	COG2885	chlorophyll binding
M482_2750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M482_2751	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M482_2753	COG0140	phosphoribosyl-ATP diphosphatase activity
M482_2753	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M482_2756	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M482_2757	COG0131	Imidazoleglycerol-phosphate dehydratase
M482_2757	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M482_2759	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M482_2761	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M482_2763	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_2764	COG1129	ABC transporter
M482_2765	COG1129	ABC transporter
M482_2766	COG0371	Dehydrogenase
M482_2768	COG0531	amino acid
M482_2769	COG2925	Exonuclease
M482_277	COG3064	Membrane
M482_277	COG3064	Membrane
M482_2772	COG1470	cell adhesion involved in biofilm formation
M482_2772	COG1388	LysM domain
M482_2773	COG3328	transposase activity
M482_2774	COG2271	Major facilitator Superfamily
M482_2775	COG3011	Protein conserved in bacteria
M482_2776	COG1028	Short-chain dehydrogenase reductase Sdr
M482_2778	COG4948	Mandelate Racemase Muconate Lactonizing
M482_278	COG0848	biopolymer transport protein
M482_2782	COG0534	Mate efflux family protein
M482_2786	COG3122	Protein conserved in bacteria
M482_279	COG0811	peptide transport
M482_2791	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M482_2796	COG2223	nitrite transmembrane transporter activity
M482_28	COG0542	response to heat
M482_280	COG0824	Thioesterase
M482_2802	COG1943	Transposase
M482_2803	COG1132	(ABC) transporter
M482_2805	COG2207	Transcriptional regulator
M482_281	COG3790	cyd operon protein YbgE
M482_2812	COG1113	amino acid transport
M482_2815	COG1278	Cold shock
M482_2817	COG2226	methyltransferase
M482_2819	COG3447	MASE1 domain protein
M482_2819	COG5001	Diguanylate cyclase
M482_2819	COG5002	protein histidine kinase activity
M482_282	COG4890	Cyd operon protein YbgT
M482_2823	COG3716	PTS system mannose fructose sorbose family IID component
M482_2824	COG3715	PTS system
M482_2825	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M482_2825	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_2826	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M482_2826	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_2827	COG1253	flavin adenine dinucleotide binding
M482_2828	COG1846	Transcriptional regulator
M482_283	COG1294	oxidase, subunit
M482_2831	COG1012	belongs to the aldehyde dehydrogenase family
M482_2832	COG3384	dioxygenase
M482_2834	COG3971	2-oxopent-4-enoate hydratase activity
M482_2837	COG2368	4-hydroxyphenylacetate
M482_2838	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M482_2839	COG1760	l-serine dehydratase
M482_284	COG1271	oxidase subunit
M482_2844	COG0513	Belongs to the DEAD box helicase family
M482_2845	COG3141	response to X-ray
M482_2848	COG1770	oligopeptidase
M482_285	COG1943	Transposase
M482_2851	COG1528	Iron-storage protein
M482_2852	COG2372	response to copper ion
M482_2857	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M482_2858	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M482_286	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M482_2863	COG3418	PFAM FlgN family protein
M482_2864	COG2747	anti-sigma28 factor FlgM
M482_2866	COG1815	bacterial-type flagellum-dependent cell motility
M482_2867	COG1558	bacterial-type flagellum-dependent cell motility
M482_2868	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M482_2869	COG1749	Flagellar hook protein flgE
M482_2871	COG4786	Flagellar basal body rod
M482_2875	COG1256	bacterial-type flagellum assembly
M482_2877	COG2390	Transcriptional regulator
M482_2878	COG3347	Dehydrogenase
M482_2878	COG1028	Short-chain dehydrogenase reductase Sdr
M482_288	COG0508	dehydrogenase complex catalyzes the overall conversion of
M482_2880	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_2882	COG1129	ABC transporter
M482_2883	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_2884	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M482_2888	COG1987	bacterial-type flagellum assembly
M482_289	COG0567	Dehydrogenase, E1 component
M482_2893	COG1580	Controls the rotational direction of flagella during chemotaxis
M482_2895	COG2882	bacterial-type flagellum organization
M482_2896	COG1157	protein secretion by the type III secretion system
M482_2898	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M482_2900	COG1677	Flagellar hook-basal body complex protein FliE
M482_2903	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M482_2904	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
M482_291	COG1053	succinate dehydrogenase
M482_2910	COG1191	sigma factor activity
M482_2912	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M482_2919	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M482_2919	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M482_2919	COG0506	proline dehydrogenase activity
M482_292	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M482_2924	COG2837	iron assimilation
M482_2927	COG1113	amino acid transport
M482_293	COG2009	succinate dehydrogenase
M482_2931	COG3136	membrane protein required for alginate biosynthesis
M482_2933	COG2197	response regulator
M482_2956	COG3328	transposase activity
M482_2957	COG3328	transposase activity
M482_296	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M482_2964	COG0673	inositol 2-dehydrogenase activity
M482_2966	COG1175	transmembrane transport
M482_2967	COG0395	ABC-type sugar transport system, permease component
M482_297	COG0497	DNA recombination
M482_298	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M482_2980	COG4771	TonB-dependent receptor
M482_2981	COG1021	2,3-dihydroxybenzoate-AMP ligase
M482_2985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M482_2985	COG2226	methyltransferase
M482_2985	COG3433	isochorismatase activity
M482_2988	COG1132	(ABC) transporter
M482_2989	COG2814	Major facilitator Superfamily
M482_2990	COG1169	isochorismate synthase
M482_2991	COG0582	viral genome integration into host DNA
M482_2994	COG3328	transposase activity
M482_2995	COG3121	Chaperone
M482_2997	COG3188	usher protein
M482_3	COG0539	negative regulation of cytoplasmic translation
M482_30	COG1278	Cold shock
M482_300	COG2867	negative regulation of translational initiation
M482_3000	COG2205	protein histidine kinase activity
M482_3000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M482_3003	COG0427	acetyl-CoA hydrolase
M482_3004	COG2030	dehydratase
M482_3012	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M482_3013	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M482_3015	COG1349	DNA-binding transcription factor activity
M482_3016	COG2066	Belongs to the glutaminase family
M482_3019	COG0672	)-iron permease
M482_3022	COG1136	(ABC) transporter
M482_3022	COG0577	efflux transmembrane transporter activity
M482_3024	COG0577	efflux transmembrane transporter activity
M482_3024	COG1136	(ABC) transporter
M482_3028	COG0006	proline dipeptidase activity
M482_3029	COG0457	Tetratricopeptide repeat
M482_303	COG0582	viral genome integration into host DNA
M482_3030	COG1649	PFAM Uncharacterised BCR, COG1649
M482_3030	COG0726	polysaccharide deacetylase
M482_3031	COG1215	transferase activity, transferring glycosyl groups
M482_3032	COG3658	cytochrome
M482_3035	COG1702	phosphate starvation-inducible protein PhoH
M482_3036	COG1943	Transposase
M482_3037	COG0387	Pfam Sodium calcium exchanger
M482_3039	COG3850	Histidine kinase
M482_3040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M482_3049	COG3328	transposase activity
M482_3055	COG0402	S-adenosylhomocysteine deaminase activity
M482_3058	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M482_3059	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M482_3060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M482_3069	COG3328	transposase activity
M482_3074	COG0500	methyltransferase
M482_3083	COG5002	protein histidine kinase activity
M482_3088	COG0745	RESPONSE REGULATOR receiver
M482_3098	COG0012	GTP binding
M482_3101	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M482_3106	COG2890	protein-(glutamine-N5) methyltransferase activity
M482_3107	COG3094	Invasion gene expression up-regulator, SirB
M482_3108	COG2912	Transglutaminase-like superfamily
M482_3110	COG0659	secondary active sulfate transmembrane transporter activity
M482_3114	COG3833	ABC-type maltose transport systems, permease component
M482_3115	COG1176	ABC-type spermidine putrescine transport system, permease component I
M482_3117	COG1943	Transposase
M482_3118	COG3842	ATPase activity
M482_3119	COG0584	glycerophosphoryl diester phosphodiesterase
M482_3120	COG1940	carbohydrate kinase activity
M482_3123	COG3381	protein complex oligomerization
M482_3126	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M482_3127	COG0673	inositol 2-dehydrogenase activity
M482_3128	COG0728	peptidoglycan biosynthetic process
M482_313	COG3657	addiction module killer protein
M482_3132	COG3102	Protein conserved in bacteria
M482_3136	COG3788	relative of glutathione S-transferase, MAPEG superfamily
M482_3137	COG1801	Protein of unknown function DUF72
M482_3139	COG0494	nUDIX hydrolase
M482_3142	COG1943	Transposase
M482_3145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M482_3147	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
M482_3148	COG0739	heme binding
M482_3149	COG1560	Kdo2-lipid A biosynthetic process
M482_3150	COG0469	pyruvate kinase activity
M482_3151	COG1737	Transcriptional regulator
M482_3152	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M482_3154	COG0800	Aldolase
M482_3157	COG0251	oxidation-reduction process
M482_3158	COG1199	ATP-dependent helicase activity
M482_3160	COG3065	identical protein binding
M482_3161	COG0318	PFAM AMP-dependent synthetase and ligase
M482_3162	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
M482_3163	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
M482_3164	COG2894	cell division
M482_3167	COG2951	lytic endotransglycosylase activity
M482_3168	COG0179	Fumarylacetoacetate (FAA) hydrolase
M482_317	COG0582	viral genome integration into host DNA
M482_3170	COG0582	viral genome integration into host DNA
M482_318	COG2963	transposase activity
M482_32	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M482_320	COG0596	Alpha beta hydrolase
M482_3205	COG1943	Transposase
M482_3223	COG1104	cysteine desulfurase activity
M482_3229	COG2719	SpoVR family
M482_3231	COG2814	Major facilitator Superfamily
M482_3233	COG0583	DNA-binding transcription factor activity
M482_3236	COG2766	serine protein kinase
M482_3237	COG3713	MltA-interacting MipA family protein
M482_324	COG0735	belongs to the Fur family
M482_3241	COG3139	Protein of unknown function (DUF1315)
M482_3242	COG1335	isochorismatase
M482_3243	COG0252	asparaginase activity
M482_3244	COG0616	signal peptide processing
M482_3245	COG0778	Nitroreductase
M482_3246	COG0709	Synthesizes selenophosphate from selenide and ATP
M482_3247	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M482_3249	COG0494	nUDIX hydrolase
M482_3250	COG0708	Exodeoxyribonuclease III
M482_3251	COG0583	DNA-binding transcription factor activity
M482_3252	COG3328	transposase activity
M482_3255	COG0788	formyltetrahydrofolate deformylase activity
M482_3257	COG0745	RESPONSE REGULATOR receiver
M482_3259	COG3328	transposase activity
M482_3261	COG1435	thymidine kinase activity
M482_3262	COG1012	belongs to the aldehyde dehydrogenase family
M482_3262	COG1454	alcohol dehydrogenase
M482_3263	COG2095	MarC family integral membrane protein
M482_3265	COG0601	transmembrane transport
M482_3266	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M482_3267	COG0444	Belongs to the ABC transporter superfamily
M482_3268	COG4608	Belongs to the ABC transporter superfamily
M482_3275	COG2350	Protein conserved in bacteria
M482_3277	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
M482_3278	COG3328	transposase activity
M482_3279	COG1607	acyl-coa hydrolase
M482_3284	COG3047	cAMP biosynthetic process
M482_3288	COG0135	phosphoribosylanthranilate isomerase activity
M482_3288	COG0134	indole-3-glycerol-phosphate synthase activity
M482_3290	COG0512	Glutamine amidotransferase of anthranilate synthase
M482_3293	COG0009	L-threonylcarbamoyladenylate synthase
M482_3294	COG1187	pseudouridine synthase activity
M482_3296	COG1028	Short-chain dehydrogenase reductase Sdr
M482_3297	COG0616	signal peptide processing
M482_33	COG2990	Protein conserved in bacteria
M482_330	COG1263	PTS System
M482_330	COG2190	(PTS) system
M482_330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M482_3300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M482_3301	COG1943	Transposase
M482_3302	COG0583	DNA-binding transcription factor activity
M482_3304	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M482_3305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M482_3306	COG0671	phosphoesterase, PA-phosphatase related
M482_3307	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
M482_3308	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
M482_3311	COG0023	Translation Initiation Factor
M482_3315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M482_3316	COG2879	small protein
M482_3317	COG1966	Carbon starvation protein
M482_3319	COG2271	Major facilitator Superfamily
M482_332	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M482_3320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M482_3321	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M482_3323	COG4659	FMN binding
M482_3324	COG4658	electron transport chain
M482_3325	COG2207	Transcriptional regulator
M482_3325	COG3708	Transcriptional regulator
M482_333	COG1846	Transcriptional regulator
M482_333	COG1940	carbohydrate kinase activity
M482_3331	COG1132	(ABC) transporter
M482_3333	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M482_3334	COG2274	protein secretion by the type I secretion system
M482_3338	COG1879	ABC-type sugar transport system periplasmic component
M482_334	COG0647	UMP catabolic process
M482_3340	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_3341	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_3343	COG0673	inositol 2-dehydrogenase activity
M482_3344	COG0385	Bile acid
M482_3346	COG5339	Protein conserved in bacteria
M482_3348	COG0114	fumarate hydratase activity
M482_335	COG0367	asparagine synthase
M482_3350	COG2814	Major facilitator Superfamily
M482_3351	COG0583	DNA-binding transcription factor activity
M482_3352	COG1940	carbohydrate kinase activity
M482_3354	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
M482_3355	COG0038	chloride channel
M482_3357	COG1609	Transcriptional regulator
M482_3359	COG1879	ABC-type sugar transport system periplasmic component
M482_3360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M482_3361	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M482_3363	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M482_3369	COG0028	Belongs to the TPP enzyme family
M482_3370	COG0440	acetolactate synthase activity
M482_3371	COG1011	Hydrolase
M482_3374	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M482_3375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M482_3376	COG0589	response to stress
M482_3377	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
M482_3378	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
M482_3380	COG0531	amino acid
M482_3382	COG0745	RESPONSE REGULATOR receiver
M482_3383	COG2205	protein histidine kinase activity
M482_3384	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M482_3389	COG3038	cytochrome b561
M482_3391	COG3591	Belongs to the peptidase S1B family
M482_3394	COG1643	Atp-dependent helicase
M482_3396	COG2390	Transcriptional regulator
M482_3397	COG0246	Mannitol dehydrogenase
M482_3398	COG3784	Protein of unknown function (DUF1318)
M482_34	COG3593	DNA synthesis involved in DNA repair
M482_3400	COG2911	Protein conserved in bacteria
M482_3401	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M482_3402	COG3187	Heat shock protein
M482_3403	COG3042	response to heat
M482_3404	COG1285	pathogenesis
M482_3406	COG0674	pyruvate-flavodoxin oxidoreductase activity
M482_3406	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M482_3406	COG1013	pyruvate-flavodoxin oxidoreductase activity
M482_3406	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M482_3409	COG0657	acetylesterase activity
M482_3409	COG2755	lipolytic protein G-D-S-L family
M482_3412	COG4166	transmembrane transport
M482_3413	COG2866	Carboxypeptidase
M482_3414	COG4948	Mandelate Racemase Muconate Lactonizing
M482_3415	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M482_342	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M482_3423	COG3106	COG3106 Predicted ATPase
M482_3425	COG1983	PspC domain protein
M482_3427	COG1842	Phage shock protein A
M482_3428	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M482_3430	COG4166	transmembrane transport
M482_3431	COG4168	peptide transport system, permease
M482_3432	COG4171	peptide transport system, permease
M482_3434	COG4172	Belongs to the ABC transporter superfamily
M482_3435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M482_3435	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M482_3437	COG3104	oligopeptide transport
M482_344	COG1702	phosphate starvation-inducible protein PhoH
M482_3440	COG0625	glutathione transferase activity
M482_3444	COG3895	Periplasmic Protein
M482_3446	COG3133	Outer membrane lipoprotein
M482_3448	COG4989	oxidoreductase activity
M482_3449	COG3313	Fe-S protein
M482_3450	COG2194	sulfuric ester hydrolase activity
M482_3451	COG1309	transcriptional regulator
M482_3452	COG1902	pentaerythritol trinitrate reductase activity
M482_3454	COG0346	lactoylglutathione lyase activity
M482_3456	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M482_3458	COG0791	NLP P60 protein
M482_3459	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M482_346	COG4535	Mg2 and Co2 transporter CorC
M482_3462	COG0583	DNA-binding transcription factor activity
M482_3463	COG2814	Major facilitator Superfamily
M482_3464	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M482_3465	COG0307	riboflavin synthase, alpha
M482_347	COG0815	Transfers the fatty acyl group on membrane lipoproteins
M482_3470	COG4238	major outer membrane lipoprotein
M482_3474	COG1388	LysM domain
M482_3474	COG1376	ErfK ybiS ycfS ynhG family protein
M482_3477	COG0719	Fe-S assembly protein
M482_3478	COG0396	ATPase activity
M482_3479	COG0719	Fe-S assembly protein
M482_3480	COG0316	Belongs to the HesB IscA family
M482_3481	COG2050	protein possibly involved in aromatic compounds catabolism
M482_3482	COG0277	FAD linked oxidase domain protein
M482_3482	COG0247	lactate metabolic process
M482_3483	COG0628	permease
M482_3484	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M482_3484	COG0574	Belongs to the PEP-utilizing enzyme family
M482_3489	COG0791	NLP P60 protein
M482_349	COG0765	amino acid transport
M482_3497	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
M482_3498	COG0386	Belongs to the glutathione peroxidase family
M482_35	COG2431	L-lysine efflux transmembrane transporter activity
M482_350	COG0765	amino acid transport
M482_3501	COG0776	regulation of translation
M482_3502	COG0072	phenylalanine-tRNA ligase activity
M482_3502	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M482_3503	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M482_3508	COG4249	Peptidase C14 caspase catalytic subunit p20
M482_351	COG1126	abc transporter atp-binding protein
M482_3512	COG0803	Belongs to the bacterial solute-binding protein 9 family
M482_3513	COG1121	(ABC) transporter
M482_3514	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M482_3515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M482_3518	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M482_3519	COG3328	transposase activity
M482_352	COG2888	peptidyl-tyrosine sulfation
M482_3520	COG1917	Cupin 2, conserved barrel domain protein
M482_3522	COG1028	Short-chain dehydrogenase reductase Sdr
M482_3524	COG1175	transmembrane transport
M482_3525	COG0395	ABC-type sugar transport system, permease component
M482_3526	COG3842	ATPase activity
M482_3527	COG1653	transport
M482_3528	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M482_3529	COG1988	membrane-bound metal-dependent
M482_3531	COG3023	N-Acetylmuramoyl-L-alanine amidase
M482_3533	COG0823	Involved in the tonB-independent uptake of proteins
M482_3534	COG2814	Major facilitator Superfamily
M482_3535	COG3121	Chaperone
M482_3538	COG3121	Chaperone
M482_3539	COG3539	Fimbrial protein
M482_3542	COG0793	Belongs to the peptidase S41A family
M482_3544	COG1956	GAF domain-containing protein
M482_3545	COG2995	paraquat-inducible protein a
M482_3546	COG3008	intermembrane lipid transfer
M482_355	COG1466	dna polymerase III delta subunit
M482_3550	COG3121	Chaperone
M482_3562	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M482_3565	COG5295	Hep Hag repeat protein
M482_3567	COG3023	N-Acetylmuramoyl-L-alanine amidase
M482_3568	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
M482_3569	COG0745	RESPONSE REGULATOR receiver
M482_357	COG0799	negative regulation of ribosome biogenesis
M482_3571	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M482_3572	COG0840	transmembrane signaling receptor activity
M482_3573	COG0840	transmembrane signaling receptor activity
M482_3577	COG2964	Protein conserved in bacteria
M482_3579	COG0251	oxidation-reduction process
M482_3580	COG2271	Major facilitator Superfamily
M482_3581	COG0835	chemotaxis
M482_3582	COG0643	Histidine kinase
M482_3582	COG2198	Histidine kinase
M482_3583	COG1360	Flagellar Motor Protein
M482_3588	COG1285	pathogenesis
M482_3589	COG0840	transmembrane signaling receptor activity
M482_359	COG0768	penicillin binding
M482_3590	COG0840	transmembrane signaling receptor activity
M482_3592	COG1278	Cold shock
M482_3594	COG1028	Short-chain dehydrogenase reductase Sdr
M482_3594	COG0604	alcohol dehydrogenase
M482_3594	COG3321	synthase
M482_3596	COG1522	sequence-specific DNA binding
M482_360	COG0772	Belongs to the SEDS family
M482_3601	COG1733	regulation of RNA biosynthetic process
M482_3602	COG0702	epimerase
M482_3603	COG0840	transmembrane signaling receptor activity
M482_3606	COG0538	isocitrate dehydrogenase activity
M482_3607	COG1187	pseudouridine synthase activity
M482_361	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M482_3611	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M482_3613	COG0745	RESPONSE REGULATOR receiver
M482_3615	COG2850	peptidyl-arginine hydroxylation
M482_3617	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M482_3619	COG4591	ABC-type transport system involved in lipoprotein release permease component
M482_362	COG1686	Belongs to the peptidase S11 family
M482_3621	COG4591	ABC-type transport system involved in lipoprotein release permease component
M482_3622	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M482_3623	COG3134	Outer membrane lipoprotein
M482_3624	COG3328	transposase activity
M482_3627	COG1252	NADH dehydrogenase
M482_3629	COG1472	Belongs to the glycosyl hydrolase 3 family
M482_3632	COG5633	Lipoprotein
M482_3633	COG0537	adenosine 5'-monophosphoramidase activity
M482_3634	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M482_3636	COG1263	PTS System
M482_3636	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M482_3637	COG0084	hydrolase, TatD family'
M482_3638	COG0470	DNA polymerase III
M482_3640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M482_3641	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M482_3642	COG1943	Transposase
M482_3643	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M482_3645	COG1028	Short-chain dehydrogenase reductase Sdr
M482_3649	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M482_3650	COG1399	metal-binding, possibly nucleic acid-binding protein
M482_3652	COG0564	pseudouridine synthase activity
M482_3653	COG1530	ribonuclease E activity
M482_3654	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M482_3657	COG3328	transposase activity
M482_366	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M482_3661	COG0628	permease
M482_3665	COG2771	luxR family
M482_3666	COG3916	Acyl-homoserine-lactone synthase
M482_3667	COG0583	DNA-binding transcription factor activity
M482_3669	COG0477	Major facilitator Superfamily
M482_367	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M482_3671	COG0667	Aldo Keto reductase
M482_3676	COG1203	CRISPR-associated helicase, Cas3
M482_3677	COG1518	maintenance of DNA repeat elements
M482_3678	COG0668	transmembrane transport
M482_368	COG1278	Cold shock
M482_3682	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
M482_3683	COG0395	ABC-type sugar transport system, permease component
M482_3686	COG1609	Transcriptional regulator
M482_3688	COG3842	ATPase activity
M482_3689	COG3328	transposase activity
M482_369	COG1278	Cold shock
M482_3691	COG3210	domain, Protein
M482_3695	COG3210	domain, Protein
M482_3698	COG3210	domain, Protein
M482_3699	COG2831	hemolysin activation secretion protein
M482_37	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M482_370	COG2197	response regulator
M482_3700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M482_3701	COG4638	Rieske (2fe-2S)
M482_3702	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M482_3703	COG0473	3-isopropylmalate dehydrogenase activity
M482_3704	COG0583	DNA-binding transcription factor activity
M482_3705	COG1609	Transcriptional regulator
M482_3706	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_3707	COG1129	ABC transporter
M482_3709	COG1879	ABC-type sugar transport system periplasmic component
M482_3710	COG1063	alcohol dehydrogenase
M482_3714	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M482_3720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M482_3721	COG0765	amino acid transport
M482_3722	COG1126	abc transporter atp-binding protein
M482_3726	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M482_3729	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M482_3732	COG1169	isochorismate synthase
M482_3734	COG4575	ribosome binding
M482_3736	COG0129	dihydroxy-acid dehydratase activity
M482_3739	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M482_3740	COG1609	Transcriptional regulator
M482_3742	COG1028	Short-chain dehydrogenase reductase Sdr
M482_3743	COG3265	gluconokinase activity
M482_3744	COG2731	YhcH YjgK YiaL family protein
M482_3747	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M482_3748	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M482_375	COG5265	(ABC) transporter
M482_3750	COG0839	Belongs to the complex I subunit 6 family
M482_3753	COG1034	ATP synthesis coupled electron transport
M482_3755	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
M482_3757	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M482_3759	COG0583	DNA-binding transcription factor activity
M482_3760	COG0436	Aminotransferase
M482_3762	COG0490	domain, Protein
M482_3762	COG0471	metal ion transport
M482_3763	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M482_3767	COG0857	belongs to the CobB CobQ family
M482_3767	COG0280	phosphate acetyltransferase
M482_3768	COG1609	Transcriptional regulator
M482_377	COG3718	enzyme involved in inositol metabolism
M482_3771	COG3037	sugar-specific permease SgaT UlaA
M482_3772	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
M482_3773	COG0622	Phosphoesterase
M482_3774	COG0622	Phosphoesterase
M482_3776	COG1090	epimerase
M482_3777	COG4598	ABC transporter
M482_3778	COG4160	amino acid transport
M482_3779	COG4215	(ABC) transporter
M482_3780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M482_3781	COG0163	prenyltransferase activity
M482_3782	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M482_3783	COG1286	toxin biosynthetic process
M482_3784	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
M482_3785	COG0285	dihydrofolate synthase activity
M482_3787	COG0586	Pfam SNARE associated Golgi protein
M482_3789	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M482_379	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M482_3792	COG0697	spore germination
M482_3795	COG1794	racemase activity, acting on amino acids and derivatives
M482_3796	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M482_3799	COG3101	peptidyl-lysine hydroxylation
M482_38	COG0028	Belongs to the TPP enzyme family
M482_380	COG0673	inositol 2-dehydrogenase activity
M482_3800	COG0730	response to heat
M482_3803	COG2890	protein-(glutamine-N5) methyltransferase activity
M482_3805	COG2062	phosphohistidine phosphatase, SixA
M482_3808	COG3691	Protein conserved in bacteria
M482_381	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_3811	COG3088	subunit of a heme lyase
M482_3811	COG4235	cytochrome complex assembly
M482_3812	COG4235	cytochrome complex assembly
M482_3812	COG3088	subunit of a heme lyase
M482_3813	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M482_3814	COG1138	Cytochrome C-type biogenesis protein
M482_3816	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M482_3817	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M482_3818	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M482_382	COG1129	ABC transporter
M482_3822	COG1704	LemA family
M482_3824	COG2824	Alkylphosphonate utilization operon protein PhnA
M482_383	COG1879	ABC-type sugar transport system periplasmic component
M482_3830	COG3501	Rhs element vgr protein
M482_384	COG0673	inositol 2-dehydrogenase activity
M482_3843	COG3188	usher protein
M482_3844	COG3328	transposase activity
M482_3845	COG3188	usher protein
M482_3846	COG3121	Chaperone
M482_385	COG0673	inositol 2-dehydrogenase activity
M482_3858	COG2951	lytic endotransglycosylase activity
M482_386	COG3962	Belongs to the TPP enzyme family
M482_3865	COG0243	molybdopterin cofactor binding
M482_3866	COG0437	4 iron, 4 sulfur cluster binding
M482_3867	COG3302	dmso reductase anchor subunit
M482_3868	COG3381	protein complex oligomerization
M482_3874	COG3038	cytochrome b561
M482_3875	COG0436	Aminotransferase
M482_3880	COG0667	Aldo Keto reductase
M482_3883	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M482_3889	COG1943	Transposase
M482_3892	COG3530	Putative quorum-sensing-regulated virulence factor
M482_3895	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
M482_3896	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M482_3897	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M482_3899	COG2190	(PTS) system
M482_39	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
M482_3902	COG2205	protein histidine kinase activity
M482_3903	COG0745	RESPONSE REGULATOR receiver
M482_3904	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M482_3907	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M482_3909	COG0006	proline dipeptidase activity
M482_3911	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M482_3913	COG3850	Histidine kinase
M482_3913	COG5002	protein histidine kinase activity
M482_3914	COG0745	RESPONSE REGULATOR receiver
M482_3917	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M482_3918	COG4208	sulfate ABC transporter
M482_3919	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M482_392	COG2373	Large extracellular alpha-helical protein
M482_3920	COG4150	thiosulfate binding
M482_3922	COG1737	Transcriptional regulator
M482_3923	COG2731	YhcH YjgK YiaL family protein
M482_3925	COG4886	Leucine-rich repeat (LRR) protein
M482_3927	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M482_3928	COG2837	iron assimilation
M482_393	COG4953	penicillin-binding protein 1C
M482_3931	COG3111	PFAM Bacterial OB fold (BOF) protein
M482_3939	COG3005	denitrification pathway
M482_394	COG3423	Transcriptional regulator
M482_3940	COG3043	anaerobic respiration
M482_3942	COG3062	negative regulation of establishment of protein localization
M482_3943	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
M482_3943	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M482_3944	COG2197	response regulator
M482_3946	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M482_3948	COG1988	membrane-bound metal-dependent
M482_3949	COG0641	radical SAM
M482_3950	COG3119	arylsulfatase activity
M482_3951	COG3842	ATPase activity
M482_3952	COG1175	transmembrane transport
M482_3953	COG1840	ABC-type Fe3 transport system, periplasmic component
M482_3955	COG1393	Belongs to the ArsC family
M482_3957	COG1876	peptidase activity
M482_3961	COG2321	neutral zinc metallopeptidase
M482_3963	COG1943	Transposase
M482_3964	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
M482_3966	COG2716	regulation of RNA biosynthetic process
M482_3967	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M482_3970	COG0628	permease
M482_3971	COG4783	chaperone-mediated protein folding
M482_3972	COG1393	Belongs to the ArsC family
M482_3974	COG1943	Transposase
M482_3977	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M482_3978	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M482_3982	COG0581	inorganic phosphate transmembrane transporter activity
M482_3984	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M482_3985	COG0248	Ppx GppA phosphatase
M482_3986	COG2239	Acts as a magnesium transporter
M482_3987	COG0443	Heat shock 70 kDa protein
M482_3988	COG1177	transmembrane transport
M482_3989	COG1176	ABC-type spermidine putrescine transport system, permease component I
M482_3991	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M482_3993	COG3842	ATPase activity
M482_3999	COG2205	protein histidine kinase activity
M482_40	COG0702	epimerase
M482_4000	COG0745	RESPONSE REGULATOR receiver
M482_4001	COG3422	double-strand break repair
M482_4006	COG0351	phosphomethylpyrimidine kinase
M482_4009	COG3328	transposase activity
M482_4016	COG1943	Transposase
M482_4018	COG0516	GMP reductase activity
M482_4018	COG0517	IMP dehydrogenase activity
M482_4020	COG1645	bacterial-type flagellum-dependent swarming motility
M482_4023	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M482_4024	COG2976	Protein conserved in bacteria
M482_403	COG2850	peptidyl-arginine hydroxylation
M482_4032	COG3468	outer membrane autotransporter barrel domain protein
M482_4033	COG3468	outer membrane autotransporter barrel domain protein
M482_4037	COG2975	iron-sulfur cluster assembly
M482_4038	COG0633	Ferredoxin
M482_4039	COG0443	Heat shock 70 kDa protein
M482_404	COG3328	transposase activity
M482_4042	COG0822	iron-sulfur transferase activity
M482_4043	COG1104	cysteine desulfurase activity
M482_4046	COG0483	inositol monophosphate 1-phosphatase activity
M482_4047	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
M482_4048	COG3683	transport system, periplasmic component
M482_4049	COG2814	Major facilitator Superfamily
M482_405	COG3328	transposase activity
M482_4050	COG3711	transcriptional antiterminator
M482_4053	COG1017	nitric oxide dioxygenase activity
M482_4053	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M482_4056	COG2188	Transcriptional regulator
M482_4057	COG0347	Belongs to the P(II) protein family
M482_4058	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M482_4058	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M482_4059	COG2204	response regulator
M482_4060	COG3170	Tfp pilus assembly protein FimV
M482_4061	COG2205	protein histidine kinase activity
M482_4068	COG0590	tRNA wobble adenosine to inosine editing
M482_4069	COG0560	Phosphoserine phosphatase
M482_4071	COG1737	Transcriptional regulator
M482_4072	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M482_4073	COG1943	Transposase
M482_4074	COG3009	Protein conserved in bacteria
M482_4075	COG3008	intermembrane lipid transfer
M482_4075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M482_4076	COG2995	paraquat-inducible protein a
M482_4077	COG0488	(ABC) transporter
M482_4079	COG0633	Ferredoxin
M482_4079	COG3217	Mosc domain protein beta barrel domain protein
M482_4082	COG0308	aminopeptidase N
M482_4086	COG1448	Aminotransferase
M482_4087	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M482_4088	COG3108	Peptidase M15
M482_4089	COG2989	Protein conserved in bacteria
M482_4092	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
M482_4093	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
M482_4094	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M482_4095	COG3173	Aminoglycoside phosphotransferase
M482_4097	COG2835	tetraacyldisaccharide 4'-kinase activity
M482_4098	COG1278	Cold shock
M482_4099	COG5383	Protein conserved in bacteria
M482_41	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M482_410	COG0656	L-ascorbic acid biosynthetic process
M482_411	COG0667	Aldo Keto reductase
M482_4113	COG3328	transposase activity
M482_4136	COG3328	transposase activity
M482_4141	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M482_4141	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M482_4147	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M482_416	COG0671	phosphoesterase, PA-phosphatase related
M482_416	COG2453	phosphatase
M482_4163	COG1475	DNA binding
M482_4166	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
M482_4167	COG5301	cellulose 1,4-beta-cellobiosidase activity
M482_4167	COG5301	cellulose 1,4-beta-cellobiosidase activity
M482_417	COG2267	carboxylic ester hydrolase activity
M482_4174	COG3941	tape measure
M482_419	COG4589	Belongs to the CDS family
M482_4192	COG1475	DNA binding
M482_4193	COG1475	DNA binding
M482_4194	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M482_420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M482_4205	COG1943	Transposase
M482_4207	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M482_4208	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M482_4222	COG1943	Transposase
M482_4225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M482_4227	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M482_4245	COG4669	(LipO)protein
M482_4247	COG1317	bacterial-type flagellum organization
M482_4248	COG5599	Phosphatase
M482_4249	COG2963	transposase activity
M482_4250	COG2801	Transposase and inactivated derivatives
M482_4255	COG2801	Transposase and inactivated derivatives
M482_4257	COG0515	serine threonine protein kinase
M482_427	COG2501	S4 domain
M482_4274	COG2801	Transposase and inactivated derivatives
M482_4279	COG2801	Transposase and inactivated derivatives
M482_428	COG1943	Transposase
M482_4284	COG2801	Transposase and inactivated derivatives
M482_4286	COG5599	Phosphatase
M482_4288	COG3609	addiction module antidote protein, CC2985 family
M482_4290	COG1475	DNA binding
M482_4291	COG1192	Involved in chromosome partitioning
M482_4293	COG2801	Transposase and inactivated derivatives
M482_4297	COG3177	Filamentation induced by cAMP protein fic
M482_43	COG1605	Chorismate mutase
M482_4302	COG4886	Leucine-rich repeat (LRR) protein
M482_4304	COG3328	transposase activity
M482_4305	COG3328	transposase activity
M482_4308	COG0457	Tetratricopeptide repeat
M482_431	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M482_4312	COG4789	Type iii secretion
M482_4321	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M482_4322	COG4790	Type iii secretion
M482_4323	COG4794	Type iii secretion
M482_4324	COG4791	protein targeting
M482_4325	COG4792	protein secretion
M482_4327	COG2207	Transcriptional regulator
M482_433	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M482_434	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M482_435	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M482_436	COG4181	ATPase activity
M482_437	COG2755	lipolytic protein G-D-S-L family
M482_438	COG0300	oxidoreductase activity
M482_439	COG3118	belongs to the thioredoxin family
M482_44	COG1126	abc transporter atp-binding protein
M482_440	COG0330	HflC and HflK could
M482_441	COG1585	Membrane protein implicated in regulation of membrane protease activity
M482_442	COG0789	Transcriptional regulator
M482_443	COG2217	Heavy metal translocating P-type atpase
M482_444	COG3735	TraB family
M482_445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M482_448	COG0737	Belongs to the 5'-nucleotidase family
M482_449	COG0737	Belongs to the 5'-nucleotidase family
M482_45	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M482_450	COG0737	Belongs to the 5'-nucleotidase family
M482_451	COG2223	nitrite transmembrane transporter activity
M482_452	COG2223	nitrite transmembrane transporter activity
M482_453	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M482_453	COG4651	solute:proton antiporter activity
M482_454	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M482_455	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M482_459	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M482_46	COG4215	(ABC) transporter
M482_460	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
M482_461	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
M482_469	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M482_47	COG4160	amino acid transport
M482_473	COG0543	2 iron, 2 sulfur cluster binding
M482_473	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M482_479	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M482_481	COG2832	Protein of unknown function (DUF454)
M482_483	COG1196	nuclear chromosome segregation
M482_483	COG3264	Mechanosensitive ion channel
M482_484	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M482_485	COG1309	transcriptional regulator
M482_486	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M482_487	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M482_489	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M482_493	COG3695	enzyme binding
M482_494	COG3126	Type III secretion system lipoprotein chaperone (YscW)
M482_495	COG1946	Acyl-CoA thioesterase
M482_496	COG0004	ammonium transporteR
M482_497	COG0347	Belongs to the P(II) protein family
M482_498	COG1132	(ABC) transporter
M482_499	COG1132	(ABC) transporter
M482_500	COG1522	sequence-specific DNA binding
M482_503	COG4533	DNA binding
M482_505	COG0824	Thioesterase
M482_506	COG1555	photosystem II stabilization
M482_507	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M482_51	COG1120	ATPase activity
M482_510	COG0776	regulation of translation
M482_511	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M482_516	COG0271	Belongs to the BolA IbaG family
M482_517	COG3056	Lipoprotein
M482_518	COG2223	nitrite transmembrane transporter activity
M482_52	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M482_520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M482_521	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M482_522	COG1845	cytochrome c oxidase, subunit III
M482_523	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M482_525	COG2814	Major facilitator Superfamily
M482_527	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M482_528	COG0693	protein deglycase activity
M482_531	COG0142	geranyltranstransferase activity
M482_534	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M482_535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M482_538	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M482_538	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M482_543	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M482_544	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M482_545	COG1862	Preprotein translocase
M482_547	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
M482_548	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
M482_549	COG0450	alkyl hydroperoxide reductase
M482_553	COG0366	Alpha amylase catalytic
M482_555	COG1114	Component of the transport system for branched-chain amino acids
M482_557	COG5002	protein histidine kinase activity
M482_558	COG0745	RESPONSE REGULATOR receiver
M482_559	COG0420	3'-5' exonuclease activity
M482_560	COG0419	ATPase involved in DNA repair
M482_561	COG1940	carbohydrate kinase activity
M482_566	COG2226	methyltransferase
M482_577	COG2195	Cleaves the N-terminal amino acid of tripeptides
M482_581	COG1477	protein flavinylation
M482_585	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M482_586	COG1805	sodium ion transport
M482_587	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M482_588	COG0121	glutamine amidotransferase
M482_589	COG3034	peptidoglycan biosynthetic process
M482_59	COG1177	transmembrane transport
M482_591	COG1960	acyl-CoA dehydrogenase activity
M482_594	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
M482_60	COG1176	ABC-type spermidine putrescine transport system, permease component I
M482_602	COG0436	Aminotransferase
M482_605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M482_608	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M482_61	COG3842	ATPase activity
M482_617	COG2814	Major facilitator Superfamily
M482_618	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M482_62	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M482_620	COG1846	Transcriptional regulator
M482_621	COG1566	PFAM secretion protein HlyD family protein
M482_622	COG2814	Major facilitator Superfamily
M482_623	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M482_624	COG3118	belongs to the thioredoxin family
M482_626	COG1042	CoA-binding domain protein
M482_626	COG0045	succinate-CoA ligase (ADP-forming) activity
M482_626	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M482_627	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M482_628	COG5544	Lipoprotein
M482_641	COG0678	peroxiredoxin activity
M482_641	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M482_642	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M482_647	COG1629	transport
M482_65	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M482_651	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
M482_655	COG2801	Transposase and inactivated derivatives
M482_66	COG0569	domain protein
M482_66	COG2985	domain, Protein
M482_660	COG0195	Participates in both transcription termination and antitermination
M482_664	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M482_666	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M482_667	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M482_669	COG1534	Rna-binding protein
M482_670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M482_671	COG2027	D-alanyl-D-alanine carboxypeptidase
M482_672	COG0745	RESPONSE REGULATOR receiver
M482_673	COG0642	Histidine kinase
M482_675	COG0697	spore germination
M482_678	COG0142	geranyltranstransferase activity
M482_68	COG0671	phosphoesterase, PA-phosphatase related
M482_680	COG3423	Transcriptional regulator
M482_684	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M482_686	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M482_687	COG2105	PFAM AIG2 family protein
M482_688	COG2911	Protein conserved in bacteria
M482_689	COG0729	surface antigen
M482_69	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M482_691	COG1253	flavin adenine dinucleotide binding
M482_693	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
M482_695	COG0737	Belongs to the 5'-nucleotidase family
M482_697	COG0545	Peptidyl-prolyl cis-trans isomerase
M482_698	COG3061	Opacity-associated protein A
M482_70	COG1349	DNA-binding transcription factor activity
M482_700	COG1943	Transposase
M482_702	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M482_705	COG1073	alpha beta
M482_71	COG0814	amino acid
M482_711	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M482_717	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
M482_718	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M482_719	COG1739	Uncharacterized protein family UPF0029
M482_72	COG1686	Belongs to the peptidase S11 family
M482_728	COG0805	protein transport
M482_73	COG2011	ABC-type metal ion transport system permease component
M482_730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M482_734	COG1322	Protein conserved in bacteria
M482_735	COG0586	Pfam SNARE associated Golgi protein
M482_736	COG1966	Carbon starvation protein
M482_738	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
M482_739	COG0412	Dienelactone hydrolase
M482_742	COG0583	DNA-binding transcription factor activity
M482_743	COG0679	Auxin Efflux Carrier
M482_744	COG0584	glycerophosphoryl diester phosphodiesterase
M482_756	COG0410	ABC transporter
M482_757	COG0411	ABC transporter
M482_758	COG4177	L-phenylalanine transmembrane transporter activity
M482_759	COG0559	Belongs to the binding-protein-dependent transport system permease family
M482_760	COG0683	leucine binding
M482_762	COG1943	Transposase
M482_764	COG2177	Part of the ABC transporter FtsEX involved in
M482_765	COG2884	Cell division ATP-binding protein ftsE
M482_766	COG0552	protein localization to endoplasmic reticulum
M482_766	COG0552	protein localization to endoplasmic reticulum
M482_767	COG0742	ribosomal rna small subunit methyltransferase
M482_768	COG3776	membrane
M482_771	COG3714	YhhN family
M482_774	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M482_776	COG0247	lactate metabolic process
M482_778	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M482_779	COG0584	glycerophosphoryl diester phosphodiesterase
M482_78	COG0625	glutathione transferase activity
M482_781	COG0561	phosphatase activity
M482_782	COG2267	carboxylic ester hydrolase activity
M482_783	COG1280	lysine exporter protein (LysE YggA)
M482_784	COG1280	lysine exporter protein (LysE YggA)
M482_785	COG0514	ATP-dependent DNA helicase (RecQ)
M482_786	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
M482_787	COG2050	protein possibly involved in aromatic compounds catabolism
M482_789	COG0598	Magnesium transport protein CorA
M482_79	COG4771	TonB-dependent receptor
M482_790	COG5564	TIM-barrel signal transduction protein
M482_791	COG5441	Belongs to the UPF0261 family
M482_793	COG0210	DNA helicase
M482_794	COG1011	Hydrolase
M482_795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M482_796	COG3159	Protein conserved in bacteria
M482_798	COG5567	small periplasmic lipoprotein
M482_8	COG5295	Hep Hag repeat protein
M482_8	COG5295	Hep Hag repeat protein
M482_800	COG3072	Adenylate cyclase
M482_802	COG1587	Uroporphyrinogen-III synthase
M482_803	COG2959	enzyme of heme biosynthesis
M482_804	COG3071	HemY protein
M482_81	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M482_811	COG1113	amino acid transport
M482_815	COG2244	polysaccharide biosynthetic process
M482_816	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M482_817	COG0456	acetyltransferase
M482_818	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M482_819	COG1088	dTDP-glucose 4,6-dehydratase activity
M482_820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M482_821	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M482_822	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M482_823	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M482_824	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M482_825	COG3118	belongs to the thioredoxin family
M482_829	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M482_832	COG3121	Chaperone
M482_835	COG3121	Chaperone
M482_84	COG0833	amino acid
M482_842	COG0583	DNA-binding transcription factor activity
M482_850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M482_851	COG3978	acetolactate synthase activity
M482_854	COG3085	chromosome segregation
M482_855	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_857	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_858	COG1129	ABC transporter
M482_859	COG1879	ABC-type sugar transport system periplasmic component
M482_86	COG0583	DNA-binding transcription factor activity
M482_869	COG0151	Belongs to the GarS family
M482_87	COG2855	membrane
M482_872	COG3068	Protein conserved in bacteria
M482_873	COG1515	deoxyribonuclease V activity
M482_878	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
M482_880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M482_885	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
M482_89	COG3188	usher protein
M482_893	COG0250	Participates in transcription elongation, termination and antitermination
M482_894	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M482_9	COG0252	asparaginase activity
M482_90	COG3121	Chaperone
M482_905	COG2986	histidine ammonia-lyase
M482_908	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M482_911	COG4607	ABC-type enterochelin transport system periplasmic component
M482_913	COG4605	iron ion homeostasis
M482_915	COG4604	ABC transporter, ATP-binding protein
M482_922	COG0582	viral genome integration into host DNA
M482_924	COG2207	Transcriptional regulator
M482_924	COG1609	Transcriptional regulator
M482_925	COG4214	carbohydrate transport
M482_927	COG4213	ABC transporter substrate-binding protein
M482_929	COG1070	Carbohydrate kinase
M482_93	COG3710	Transcriptional regulator
M482_931	COG3121	Chaperone
M482_932	COG3188	usher protein
M482_933	COG3188	usher protein
M482_935	COG3274	enterobacterial common antigen metabolic process
M482_937	COG2801	Transposase and inactivated derivatives
M482_939	COG0527	aspartate kinase activity
M482_939	COG0460	homoserine dehydrogenase
M482_94	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M482_94	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M482_94	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M482_940	COG0626	cystathionine gamma-synthase activity
M482_942	COG4682	membrane
M482_944	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M482_946	COG1609	Transcriptional regulator
M482_947	COG1609	Transcriptional regulator
M482_948	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M482_95	COG1105	Belongs to the carbohydrate kinase PfkB family
M482_951	COG1575	Belongs to the MenA family. Type 1 subfamily
M482_959	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M482_960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M482_961	COG1494	fructose-1,6-bisphosphatase
M482_963	COG3152	Membrane
M482_966	COG0583	DNA-binding transcription factor activity
M482_967	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M482_968	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M482_969	COG0471	metal ion transport
M482_97	COG0494	nUDIX hydrolase
M482_970	COG0471	metal ion transport
M482_972	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M482_977	COG3678	ATP-independent chaperone mediated protein folding
M482_978	COG0745	RESPONSE REGULATOR receiver
M482_979	COG2205	protein histidine kinase activity
M482_98	COG1172	Belongs to the binding-protein-dependent transport system permease family
M482_980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M482_980	COG2169	Transcriptional regulator
M482_981	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M482_982	COG1045	serine acetyltransferase
M482_985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M482_986	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M482_988	COG4942	peptidase
M482_989	COG2861	carbohydrate metabolic process
M482_99	COG1129	ABC transporter
M482_990	COG2861	carbohydrate metabolic process
M482_992	COG0156	8-amino-7-oxononanoate synthase activity
M482_994	COG0859	PFAM glycosyl transferase family 9
M482_995	COG0859	PFAM glycosyl transferase family 9
M482_996	COG1519	Transferase