locus-tag	class	description
A1122_00055	COG2771	luxR family
A1122_00060	COG3916	Acyl-homoserine-lactone synthase
A1122_00180	COG1662	PFAM IS1 transposase
A1122_00195	COG1982	Orn Lys Arg decarboxylase major
A1122_00200	COG1879	ABC-type sugar transport system periplasmic component
A1122_00205	COG1129	ABC transporter
A1122_00210	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_00215	COG4774	siderophore transport
A1122_00240	COG1194	a g-specific adenine glycosylase
A1122_00250	COG3171	Protein conserved in bacteria
A1122_00255	COG2066	Belongs to the glutaminase family
A1122_00270	COG3064	Membrane
A1122_00270	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
A1122_00270	COG1073	alpha beta
A1122_00275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A1122_00280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A1122_00290	COG0762	integral membrane protein
A1122_00295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A1122_00300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A1122_00305	COG2805	Type II/IV secretion system protein
A1122_00315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1122_00330	COG0189	ligase activity
A1122_00335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A1122_00340	COG2356	endonuclease I
A1122_00345	COG3091	SprT-like family
A1122_00355	COG1166	arginine decarboxylase activity
A1122_00370	COG0501	Belongs to the peptidase M48B family
A1122_00375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A1122_00380	COG1943	Transposase
A1122_00405	COG0191	fructose-bisphosphate aldolase activity
A1122_00435	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A1122_00440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A1122_00450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A1122_00465	COG0006	proline dipeptidase activity
A1122_00470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1122_00475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1122_00520	COG1272	protein, Hemolysin III
A1122_00535	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A1122_00545	COG0745	RESPONSE REGULATOR receiver
A1122_00550	COG2205	protein histidine kinase activity
A1122_00555	COG4452	Inner membrane protein CreD
A1122_00560	COG0716	FMN binding
A1122_00565	COG4974	Belongs to the 'phage' integrase family
A1122_00570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A1122_00575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A1122_00590	COG0582	viral genome integration into host DNA
A1122_00625	COG2944	sequence-specific DNA binding
A1122_00720	COG1695	Transcriptional regulator
A1122_00725	COG0791	NLP P60 protein
A1122_00735	COG1879	ABC-type sugar transport system periplasmic component
A1122_00740	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_00745	COG1129	ABC transporter
A1122_00755	COG2182	Extracellular solute-binding protein
A1122_00760	COG1175	transmembrane transport
A1122_00765	COG3833	ABC-type maltose transport systems, permease component
A1122_00770	COG3867	Arabinogalactan endo-beta-1,4-galactanase
A1122_00775	COG1874	Beta-galactosidase
A1122_00780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_00780	COG1263	PTS System
A1122_00805	COG2271	Major facilitator Superfamily
A1122_00820	COG0191	fructose-bisphosphate aldolase activity
A1122_00830	COG3119	arylsulfatase activity
A1122_00835	COG0641	radical SAM
A1122_00845	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_00855	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_00860	COG3716	PTS system mannose fructose sorbose family IID component
A1122_00865	COG3715	PTS system
A1122_00870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_00875	COG2222	sugar isomerase
A1122_00885	COG1349	DNA-binding transcription factor activity
A1122_00895	COG3119	arylsulfatase activity
A1122_00905	COG1943	Transposase
A1122_00940	COG0288	reversible hydration of carbon dioxide
A1122_00985	COG2165	general secretion pathway protein
A1122_01030	COG0840	transmembrane signaling receptor activity
A1122_01045	COG0583	DNA-binding transcription factor activity
A1122_01050	COG2814	Major facilitator Superfamily
A1122_01055	COG0583	DNA-binding transcription factor activity
A1122_01060	COG0019	diaminopimelate decarboxylase activity
A1122_01065	COG1609	Transcriptional regulator
A1122_01095	COG0667	Aldo Keto reductase
A1122_01145	COG2226	methyltransferase
A1122_01145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1122_01145	COG3433	isochorismatase activity
A1122_01150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1122_01155	COG3433	isochorismatase activity
A1122_01155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1122_01155	COG2226	methyltransferase
A1122_01190	COG1132	(ABC) transporter
A1122_01205	COG2610	gluconate transmembrane transporter activity
A1122_01220	COG3501	Rhs element vgr protein
A1122_01230	COG3209	COG3209 Rhs family protein
A1122_01250	COG0471	metal ion transport
A1122_01265	COG2801	Transposase and inactivated derivatives
A1122_01315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A1122_01320	COG1191	sigma factor activity
A1122_01345	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A1122_01370	COG3710	Transcriptional regulator
A1122_01390	COG1256	bacterial-type flagellum assembly
A1122_01400	COG1706	bacterial-type flagellum-dependent cell motility
A1122_01405	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A1122_01410	COG4786	Flagellar basal body rod
A1122_01420	COG1943	Transposase
A1122_01430	COG1749	Flagellar hook protein flgE
A1122_01435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A1122_01440	COG1558	bacterial-type flagellum-dependent cell motility
A1122_01445	COG1815	bacterial-type flagellum-dependent cell motility
A1122_01450	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
A1122_01495	COG2204	response regulator
A1122_01515	COG1987	bacterial-type flagellum assembly
A1122_01520	COG1684	flagellar biosynthetic protein fliR
A1122_01525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1122_01550	COG4592	Periplasmic binding protein
A1122_01570	COG1943	Transposase
A1122_01580	COG1943	Transposase
A1122_01595	COG4964	Belongs to the GSP D family
A1122_01600	COG4964	Belongs to the GSP D family
A1122_01650	COG0848	biopolymer transport protein
A1122_01655	COG0811	peptide transport
A1122_01660	COG0626	cystathionine gamma-synthase activity
A1122_01665	COG0586	Pfam SNARE associated Golgi protein
A1122_01670	COG2207	Transcriptional regulator
A1122_01675	COG1979	alcohol dehydrogenase
A1122_01685	COG0656	L-ascorbic acid biosynthetic process
A1122_01700	COG2132	Multicopper oxidase
A1122_01705	COG0204	Acyl-transferase
A1122_01710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A1122_01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
A1122_01720	COG0583	DNA-binding transcription factor activity
A1122_01725	COG0187	DNA topoisomerase II activity
A1122_01730	COG3150	esterase
A1122_01735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A1122_01740	COG3151	Protein conserved in bacteria
A1122_01745	COG0494	nUDIX hydrolase
A1122_01750	COG1538	Outer membrane efflux protein
A1122_01765	COG0754	glutathionylspermidine amidase activity
A1122_01770	COG3384	dioxygenase
A1122_01800	COG0531	amino acid
A1122_01815	COG3025	triphosphatase activity
A1122_01820	COG4991	sh3 domain protein
A1122_01835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A1122_01860	COG0358	DNA primase activity
A1122_01865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A1122_01945	COG0251	oxidation-reduction process
A1122_01985	COG1289	transmembrane transporter activity
A1122_02005	COG0395	ABC-type sugar transport system, permease component
A1122_02015	COG1653	transport
A1122_02020	COG1609	Transcriptional regulator
A1122_02025	COG3459	Glycosyltransferase 36 associated
A1122_02030	COG3842	ATPase activity
A1122_02050	COG3210	domain, Protein
A1122_02055	COG3210	domain, Protein
A1122_02065	COG3210	domain, Protein
A1122_02070	COG3210	domain, Protein
A1122_02080	COG3210	domain, Protein
A1122_02085	COG2831	hemolysin activation secretion protein
A1122_02090	COG4245	von Willebrand factor, type A
A1122_02105	COG4245	von Willebrand factor, type A
A1122_02120	COG3247	response to pH
A1122_02125	COG1902	pentaerythritol trinitrate reductase activity
A1122_02125	COG0446	pyridine nucleotide-disulphide oxidoreductase
A1122_02140	COG1451	nucleotide metabolic process
A1122_02145	COG0673	inositol 2-dehydrogenase activity
A1122_02155	COG1943	Transposase
A1122_02165	COG2721	sulfolactate sulfo-lyase activity
A1122_02170	COG0246	Mannitol dehydrogenase
A1122_02180	COG2271	Major facilitator Superfamily
A1122_02195	COG0586	Pfam SNARE associated Golgi protein
A1122_02210	COG4575	ribosome binding
A1122_02215	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A1122_02225	COG2259	Doxx family
A1122_02230	COG0435	Glutathione S-transferase
A1122_02250	COG0494	nUDIX hydrolase
A1122_02280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A1122_02285	COG0849	cell division
A1122_02290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A1122_02310	COG0772	Belongs to the SEDS family
A1122_02325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A1122_02330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A1122_02335	COG0768	penicillin binding
A1122_02340	COG3116	cell division
A1122_02365	COG1609	Transcriptional regulator
A1122_02370	COG1943	Transposase
A1122_02380	COG0028	Belongs to the TPP enzyme family
A1122_02385	COG1022	Amp-dependent synthetase and ligase
A1122_02405	COG1943	Transposase
A1122_02415	COG0473	3-isopropylmalate dehydrogenase activity
A1122_02430	COG2814	Major facilitator Superfamily
A1122_02445	COG2814	Major facilitator Superfamily
A1122_02460	COG4143	(ABC) transporter
A1122_02465	COG1178	ABC-type Fe3 transport system permease component
A1122_02475	COG0586	Pfam SNARE associated Golgi protein
A1122_02480	COG0417	DNA replication proofreading
A1122_02505	COG3047	cAMP biosynthetic process
A1122_02505	COG2885	chlorophyll binding
A1122_02550	COG3501	Rhs element vgr protein
A1122_02600	COG0564	pseudouridine synthase activity
A1122_02605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A1122_02615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1122_02620	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A1122_02650	COG1943	Transposase
A1122_02655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A1122_02665	COG2966	Psort location CytoplasmicMembrane, score
A1122_02670	COG1280	lysine exporter protein (LysE YggA)
A1122_02675	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A1122_02680	COG0505	Belongs to the CarA family
A1122_02690	COG1943	Transposase
A1122_02700	COG1047	Peptidyl-prolyl cis-trans
A1122_02715	COG0196	riboflavin kinase activity
A1122_02725	COG0583	DNA-binding transcription factor activity
A1122_02745	COG1584	GPR1 FUN34 yaaH family protein
A1122_02760	COG0521	Mo-molybdopterin cofactor biosynthetic process
A1122_02790	COG0745	RESPONSE REGULATOR receiver
A1122_02795	COG3045	CreA protein
A1122_02800	COG3708	Transcriptional regulator
A1122_02800	COG2207	Transcriptional regulator
A1122_02815	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
A1122_02820	COG0741	lytic transglycosylase activity
A1122_02835	COG2199	diguanylate cyclase activity
A1122_02840	COG2885	chlorophyll binding
A1122_02845	COG0488	(ABC) transporter
A1122_02850	COG0488	(ABC) transporter
A1122_02870	COG0560	Phosphoserine phosphatase
A1122_02875	COG3726	membrane protein affecting hemolysin expression
A1122_02910	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A1122_02915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1122_02925	COG0084	hydrolase, TatD family'
A1122_02930	COG4667	esterase of the alpha-beta hydrolase superfamily
A1122_02940	COG2823	Periplasmic or secreted lipoprotein
A1122_02950	COG0456	acetyltransferase
A1122_02955	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A1122_02975	COG3706	GGDEF domain
A1122_03000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_03005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_03020	COG0859	PFAM glycosyl transferase family 9
A1122_03030	COG2390	Transcriptional regulator
A1122_03035	COG2390	Transcriptional regulator
A1122_03080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_03080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A1122_03080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_03085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_03090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_03095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_03100	COG2207	Transcriptional regulator
A1122_03110	COG4269	membrane
A1122_03165	COG2963	transposase activity
A1122_03170	COG2801	Transposase and inactivated derivatives
A1122_03180	COG1401	restriction endodeoxyribonuclease activity
A1122_03200	COG3650	response to hydrogen peroxide
A1122_03205	COG1960	acyl-CoA dehydrogenase activity
A1122_03215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1122_03220	COG0557	exoribonuclease II activity
A1122_03235	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A1122_03240	COG0330	HflC and HflK could
A1122_03245	COG0330	HflC and HflK could
A1122_03250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A1122_03270	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1122_03280	COG0802	atpase or kinase
A1122_03285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A1122_03285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A1122_03290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A1122_03295	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A1122_03315	COG1511	domain protein
A1122_03315	COG3264	Mechanosensitive ion channel
A1122_03330	COG1053	succinate dehydrogenase
A1122_03335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A1122_03345	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
A1122_03355	COG1943	Transposase
A1122_03360	COG2076	Multidrug Resistance protein
A1122_03405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1122_03420	COG3383	formate dehydrogenase (NAD+) activity
A1122_03425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_03430	COG0493	'glutamate synthase
A1122_03430	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_03435	COG1309	transcriptional regulator
A1122_03505	COG1454	alcohol dehydrogenase
A1122_03515	COG0629	single-stranded DNA binding
A1122_03520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A1122_03525	COG2315	Protein conserved in bacteria
A1122_03530	COG1448	Aminotransferase
A1122_03535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A1122_03540	COG0305	Participates in initiation and elongation during chromosome replication
A1122_03555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1122_03560	COG0735	belongs to the Fur family
A1122_03570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A1122_03615	COG3121	Chaperone
A1122_03675	COG1358	cellular component organization or biogenesis
A1122_03700	COG3721	Heme iron utilization protein
A1122_03705	COG0702	epimerase
A1122_03715	COG4771	TonB-dependent receptor
A1122_03720	COG3720	iron ion transport
A1122_03725	COG4558	Periplasmic binding protein
A1122_03730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_03740	COG0626	cystathionine gamma-synthase activity
A1122_03745	COG0814	amino acid
A1122_03750	COG0583	DNA-binding transcription factor activity
A1122_03755	COG0425	Belongs to the sulfur carrier protein TusA family
A1122_03760	COG2391	methyltransferase activity
A1122_03875	COG1301	dicarboxylic acid transport
A1122_03885	COG3162	membrane
A1122_03910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A1122_03925	COG0551	DNA topoisomerase type I activity
A1122_03935	COG0758	DNA mediated transformation
A1122_03955	COG0569	domain protein
A1122_03965	COG3036	rescue of stalled ribosome
A1122_03970	COG0789	Transcriptional regulator
A1122_03985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A1122_04000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A1122_04005	COG0201	protein transport
A1122_04015	COG1841	ribosomal large subunit assembly
A1122_04055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A1122_04060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A1122_04070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A1122_04075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A1122_04085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A1122_04110	COG0051	transcription antitermination factor activity, RNA binding
A1122_04125	COG1943	Transposase
A1122_04140	COG0049	tRNA binding
A1122_04145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A1122_04165	COG2964	Protein conserved in bacteria
A1122_04170	COG0545	Peptidyl-prolyl cis-trans isomerase
A1122_04180	COG1047	Peptidyl-prolyl cis-trans
A1122_04185	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A1122_04210	COG1216	Glycosyl transferase, family 2
A1122_04220	COG2175	clavaminate synthase activity
A1122_04225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1122_04235	COG4521	taurine ABC transporter
A1122_04245	COG0429	hydrolase of the alpha beta-hydrolase fold
A1122_04255	COG3954	Phosphoribulokinase
A1122_04265	COG1765	OsmC-like protein
A1122_04275	COG1289	transmembrane transporter activity
A1122_04295	COG0433	COG0433 Predicted ATPase
A1122_04300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A1122_04305	COG1486	melibiose metabolic process
A1122_04335	COG0402	S-adenosylhomocysteine deaminase activity
A1122_04340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A1122_04345	COG2146	nitrite reductase [NAD(P)H] activity
A1122_04360	COG0180	Tryptophanyl-tRNA synthetase
A1122_04365	COG0546	phosphoglycolate phosphatase activity
A1122_04370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A1122_04395	COG4796	Type ii and iii secretion system protein
A1122_04420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A1122_04425	COG0494	nUDIX hydrolase
A1122_04435	COG1011	Hydrolase
A1122_04440	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A1122_04460	COG0745	RESPONSE REGULATOR receiver
A1122_04465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A1122_04470	COG2183	response to ionizing radiation
A1122_04480	COG1918	ferrous iron import across plasma membrane
A1122_04515	COG1640	4-alpha-glucanotransferase
A1122_04535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1122_04545	COG1349	DNA-binding transcription factor activity
A1122_04555	COG2801	Transposase and inactivated derivatives
A1122_04565	COG0527	aspartate kinase activity
A1122_04565	COG0460	homoserine dehydrogenase
A1122_04585	COG4682	membrane
A1122_04595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A1122_04605	COG1609	Transcriptional regulator
A1122_04610	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A1122_04625	COG1575	Belongs to the MenA family. Type 1 subfamily
A1122_04670	COG1943	Transposase
A1122_04680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A1122_04685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A1122_04690	COG1494	fructose-1,6-bisphosphatase
A1122_04700	COG3152	Membrane
A1122_04715	COG0583	DNA-binding transcription factor activity
A1122_04720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A1122_04725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A1122_04730	COG0471	metal ion transport
A1122_04740	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A1122_04770	COG4974	Belongs to the 'phage' integrase family
A1122_04775	COG3678	ATP-independent chaperone mediated protein folding
A1122_04780	COG0745	RESPONSE REGULATOR receiver
A1122_04785	COG2205	protein histidine kinase activity
A1122_04790	COG2169	Transcriptional regulator
A1122_04790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A1122_04795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A1122_04800	COG1045	serine acetyltransferase
A1122_04815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A1122_04820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1122_04830	COG4942	peptidase
A1122_04835	COG2861	carbohydrate metabolic process
A1122_04840	COG2861	carbohydrate metabolic process
A1122_04850	COG0156	8-amino-7-oxononanoate synthase activity
A1122_04860	COG0859	PFAM glycosyl transferase family 9
A1122_04865	COG0859	PFAM glycosyl transferase family 9
A1122_04870	COG1519	Transferase
A1122_04890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A1122_04905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A1122_04930	COG1561	YicC-like family, N-terminal region
A1122_04935	COG2860	membrane
A1122_04940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A1122_04955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A1122_04960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1122_04965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A1122_04975	COG0786	glutamate:sodium symporter activity
A1122_04985	COG2233	PERMEase
A1122_04990	COG2982	Protein involved in outer membrane biogenesis
A1122_04995	COG0456	acetyltransferase
A1122_05015	COG1295	ribonuclease BN
A1122_05020	COG1011	Hydrolase
A1122_05030	COG0174	glutamine synthetase
A1122_05035	COG3852	Histidine kinase
A1122_05045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A1122_05060	COG1943	Transposase
A1122_05065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1122_05065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1122_05070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A1122_05075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A1122_05080	COG3084	Protein conserved in bacteria
A1122_05090	COG1763	Mo-molybdopterin cofactor biosynthetic process
A1122_05095	COG3328	transposase activity
A1122_05105	COG2186	Transcriptional regulator
A1122_05110	COG0477	Major facilitator Superfamily
A1122_05120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_05150	COG1522	sequence-specific DNA binding
A1122_05155	COG0716	FMN binding
A1122_05170	COG3312	ion transport
A1122_05220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A1122_05225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A1122_05230	COG0573	inorganic phosphate transmembrane transporter activity
A1122_05235	COG0581	inorganic phosphate transmembrane transporter activity
A1122_05245	COG0704	Plays a role in the regulation of phosphate uptake
A1122_05255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_05260	COG0765	amino acid transport
A1122_05265	COG0765	amino acid transport
A1122_05270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_05275	COG2252	PERMEase
A1122_05305	COG0706	membrane insertase activity
A1122_05320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A1122_05335	COG0592	DNA-directed DNA polymerase activity
A1122_05345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A1122_05350	COG0187	DNA topoisomerase II activity
A1122_05355	COG0561	phosphatase activity
A1122_05360	COG2801	Transposase and inactivated derivatives
A1122_05370	COG2423	ornithine cyclodeaminase activity
A1122_05375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A1122_05380	COG0823	Involved in the tonB-independent uptake of proteins
A1122_05385	COG0823	Involved in the tonB-independent uptake of proteins
A1122_05390	COG5645	(Lipo)protein
A1122_05410	COG3977	Valine--pyruvate aminotransferase
A1122_05420	COG0366	Alpha amylase catalytic
A1122_05435	COG2885	chlorophyll binding
A1122_05445	COG2818	Glycosylase
A1122_05475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_05475	COG2213	PTS system mannitol-specific
A1122_05485	COG3722	fumarate hydratase activity
A1122_05515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A1122_05525	COG3383	formate dehydrogenase (NAD+) activity
A1122_05525	COG0243	molybdopterin cofactor binding
A1122_05530	COG3383	formate dehydrogenase (NAD+) activity
A1122_05530	COG0243	molybdopterin cofactor binding
A1122_05535	COG0437	4 iron, 4 sulfur cluster binding
A1122_05540	COG2864	formate dehydrogenase
A1122_05595	COG2801	Transposase and inactivated derivatives
A1122_05605	COG3274	enterobacterial common antigen metabolic process
A1122_05615	COG3188	usher protein
A1122_05620	COG3188	usher protein
A1122_05625	COG3121	Chaperone
A1122_05635	COG1070	Carbohydrate kinase
A1122_05645	COG4213	ABC transporter substrate-binding protein
A1122_05655	COG4214	carbohydrate transport
A1122_05660	COG1609	Transcriptional regulator
A1122_05660	COG2207	Transcriptional regulator
A1122_05665	COG0582	viral genome integration into host DNA
A1122_05705	COG4604	ABC transporter, ATP-binding protein
A1122_05710	COG4605	iron ion homeostasis
A1122_05720	COG4607	ABC-type enterochelin transport system periplasmic component
A1122_05735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A1122_05750	COG2986	histidine ammonia-lyase
A1122_05770	COG2194	sulfuric ester hydrolase activity
A1122_05775	COG2197	response regulator
A1122_05780	COG3851	Histidine kinase
A1122_05785	COG2271	Major facilitator Superfamily
A1122_05795	COG2831	hemolysin activation secretion protein
A1122_05805	COG0747	negative chemotaxis
A1122_05810	COG0601	transmembrane transport
A1122_05815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_05820	COG0444	Belongs to the ABC transporter superfamily
A1122_05825	COG4608	Belongs to the ABC transporter superfamily
A1122_05840	COG2199	diguanylate cyclase activity
A1122_05840	COG2200	EAL domain
A1122_05845	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A1122_05865	COG0612	Peptidase, M16
A1122_05870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_05875	COG1942	4-Oxalocrotonate Tautomerase
A1122_05880	COG2200	EAL domain
A1122_05885	COG2982	Protein involved in outer membrane biogenesis
A1122_05890	COG2134	cdp-diacylglycerol pyrophosphatase
A1122_05895	COG1295	ribonuclease BN
A1122_05920	COG1929	Belongs to the glycerate kinase type-1 family
A1122_05925	COG2610	gluconate transmembrane transporter activity
A1122_05930	COG3835	regulator
A1122_05935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1122_05940	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A1122_05945	COG0339	signal peptide processing
A1122_05965	COG0589	response to stress
A1122_05975	COG1943	Transposase
A1122_05985	COG0306	phosphate transporter
A1122_05990	COG2081	HI0933 family
A1122_06010	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_06015	COG1879	ABC-type sugar transport system periplasmic component
A1122_06025	COG0191	fructose-bisphosphate aldolase activity
A1122_06035	COG0745	RESPONSE REGULATOR receiver
A1122_06040	COG1741	Belongs to the pirin family
A1122_06045	COG1609	Transcriptional regulator
A1122_06050	COG2610	gluconate transmembrane transporter activity
A1122_06055	COG3265	gluconokinase activity
A1122_06075	COG2095	MarC family integral membrane protein
A1122_06080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A1122_06105	COG3275	phosphorelay sensor kinase activity
A1122_06120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A1122_06130	COG0058	SHG alpha-glucan phosphorylase activity
A1122_06135	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A1122_06145	COG2801	Transposase and inactivated derivatives
A1122_06180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A1122_06200	COG1629	transport
A1122_06225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1122_06230	COG0678	peroxiredoxin activity
A1122_06230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A1122_06275	COG1879	ABC-type sugar transport system periplasmic component
A1122_06280	COG1129	ABC transporter
A1122_06285	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_06290	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_06300	COG3085	chromosome segregation
A1122_06315	COG3978	acetolactate synthase activity
A1122_06320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1122_06365	COG0583	DNA-binding transcription factor activity
A1122_06400	COG3121	Chaperone
A1122_06415	COG3121	Chaperone
A1122_06425	COG3328	transposase activity
A1122_06435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1122_06470	COG3118	belongs to the thioredoxin family
A1122_06475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A1122_06480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A1122_06485	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A1122_06490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A1122_06495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A1122_06500	COG1088	dTDP-glucose 4,6-dehydratase activity
A1122_06505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A1122_06510	COG0456	acetyltransferase
A1122_06515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A1122_06520	COG2244	polysaccharide biosynthetic process
A1122_06540	COG1113	amino acid transport
A1122_06565	COG1943	Transposase
A1122_06570	COG3071	HemY protein
A1122_06575	COG2959	enzyme of heme biosynthesis
A1122_06580	COG1587	Uroporphyrinogen-III synthase
A1122_06590	COG3072	Adenylate cyclase
A1122_06605	COG5567	small periplasmic lipoprotein
A1122_06615	COG3159	Protein conserved in bacteria
A1122_06620	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A1122_06625	COG1011	Hydrolase
A1122_06630	COG0210	DNA helicase
A1122_06645	COG5441	Belongs to the UPF0261 family
A1122_06650	COG5564	TIM-barrel signal transduction protein
A1122_06655	COG0598	Magnesium transport protein CorA
A1122_06665	COG2050	protein possibly involved in aromatic compounds catabolism
A1122_06670	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
A1122_06675	COG0514	ATP-dependent DNA helicase (RecQ)
A1122_06680	COG1280	lysine exporter protein (LysE YggA)
A1122_06685	COG1280	lysine exporter protein (LysE YggA)
A1122_06690	COG2267	carboxylic ester hydrolase activity
A1122_06695	COG0561	phosphatase activity
A1122_06705	COG0584	glycerophosphoryl diester phosphodiesterase
A1122_06710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A1122_06720	COG0247	lactate metabolic process
A1122_06730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A1122_06745	COG3714	YhhN family
A1122_06760	COG3776	membrane
A1122_06765	COG0742	ribosomal rna small subunit methyltransferase
A1122_06770	COG0552	protein localization to endoplasmic reticulum
A1122_06770	COG0552	protein localization to endoplasmic reticulum
A1122_06775	COG2884	Cell division ATP-binding protein ftsE
A1122_06780	COG2177	Part of the ABC transporter FtsEX involved in
A1122_06795	COG1943	Transposase
A1122_06805	COG0683	leucine binding
A1122_06810	COG0559	Belongs to the binding-protein-dependent transport system permease family
A1122_06815	COG4177	L-phenylalanine transmembrane transporter activity
A1122_06820	COG0411	ABC transporter
A1122_06825	COG0410	ABC transporter
A1122_06885	COG0584	glycerophosphoryl diester phosphodiesterase
A1122_06890	COG0679	Auxin Efflux Carrier
A1122_06900	COG0583	DNA-binding transcription factor activity
A1122_06910	COG0412	Dienelactone hydrolase
A1122_06915	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A1122_06925	COG1966	Carbon starvation protein
A1122_06930	COG0586	Pfam SNARE associated Golgi protein
A1122_06935	COG1322	Protein conserved in bacteria
A1122_06955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A1122_06965	COG0805	protein transport
A1122_07025	COG1739	Uncharacterized protein family UPF0029
A1122_07030	COG1943	Transposase
A1122_07035	COG1739	Uncharacterized protein family UPF0029
A1122_07040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A1122_07045	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
A1122_07050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A1122_07090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A1122_07095	COG0250	Participates in transcription elongation, termination and antitermination
A1122_07130	COG1943	Transposase
A1122_07145	COG2022	thiamine diphosphate biosynthetic process
A1122_07155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A1122_07165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A1122_07185	COG1515	deoxyribonuclease V activity
A1122_07190	COG3068	Protein conserved in bacteria
A1122_07205	COG0151	Belongs to the GarS family
A1122_07225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A1122_07230	COG2224	Isocitrate lyase
A1122_07245	COG1414	Transcriptional regulator
A1122_07250	COG1414	Transcriptional regulator
A1122_07270	COG0527	aspartate kinase activity
A1122_07290	COG3833	ABC-type maltose transport systems, permease component
A1122_07295	COG1175	transmembrane transport
A1122_07355	COG2801	Transposase and inactivated derivatives
A1122_07430	COG3501	Rhs element vgr protein
A1122_07445	COG3209	COG3209 Rhs family protein
A1122_07475	COG3501	Rhs element vgr protein
A1122_07485	COG3209	COG3209 Rhs family protein
A1122_07500	COG0673	inositol 2-dehydrogenase activity
A1122_07505	COG2207	Transcriptional regulator
A1122_07505	COG1917	Cupin 2, conserved barrel domain protein
A1122_07510	COG1869	D-ribose catabolic process
A1122_07515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_07525	COG0431	NADPH-dependent FMN reductase
A1122_07530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A1122_07540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1122_07555	COG3077	Addiction module antitoxin, RelB DinJ family
A1122_07560	COG2252	PERMEase
A1122_07565	COG0025	NhaP-type Na H and K H
A1122_07575	COG1560	Kdo2-lipid A biosynthetic process
A1122_07585	COG1129	ABC transporter
A1122_07590	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_07600	COG1069	ribulokinase activity
A1122_07610	COG0625	glutathione transferase activity
A1122_07630	COG1943	Transposase
A1122_07635	COG1278	Cold shock
A1122_07640	COG1278	Cold shock
A1122_07650	COG3133	Outer membrane lipoprotein
A1122_07655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1122_07665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1122_07690	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A1122_07695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1122_07705	COG4145	pantothenate transmembrane transporter activity
A1122_07710	COG3924	membrane
A1122_07715	COG0439	Biotin carboxylase
A1122_07720	COG0511	ligase activity, forming carbon-carbon bonds
A1122_07735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A1122_07740	COG0604	alcohol dehydrogenase
A1122_07745	COG2200	EAL domain
A1122_07745	COG2199	diguanylate cyclase activity
A1122_07750	COG1077	Cell shape determining protein MreB Mrl
A1122_07755	COG1792	Involved in formation and maintenance of cell shape
A1122_07760	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A1122_07770	COG1530	ribonuclease E activity
A1122_07775	COG3164	Protein of unknown function
A1122_07780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1122_07785	COG0312	modulator of DNA gyrase
A1122_07845	COG0583	DNA-binding transcription factor activity
A1122_07865	COG1012	belongs to the aldehyde dehydrogenase family
A1122_07880	COG2732	(Barnase) inhibitor
A1122_07890	COG0312	modulator of DNA gyrase
A1122_07900	COG3783	Cytochrome b(562)
A1122_07905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A1122_07910	COG0366	Alpha amylase catalytic
A1122_07915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_07915	COG1263	PTS System
A1122_07920	COG1609	Transcriptional regulator
A1122_07955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_07965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_07980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A1122_07985	COG1137	ATPase activity
A1122_07990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A1122_07995	COG3117	lipopolysaccharide transmembrane transporter activity
A1122_08000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A1122_08005	COG0517	IMP dehydrogenase activity
A1122_08005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A1122_08010	COG0530	calcium, potassium:sodium antiporter activity
A1122_08015	COG1127	ABC transporter
A1122_08020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A1122_08025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A1122_08030	COG2854	intermembrane phospholipid transfer
A1122_08035	COG3113	response to antibiotic
A1122_08040	COG5007	Belongs to the BolA IbaG family
A1122_08050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1122_08055	COG1943	Transposase
A1122_08060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1122_08065	COG3105	Protein conserved in bacteria
A1122_08070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A1122_08090	COG0625	glutathione transferase activity
A1122_08095	COG2969	positive regulation of protein catabolic process
A1122_08105	COG0493	'glutamate synthase
A1122_08110	COG0067	glutamate synthase
A1122_08110	COG0070	glutamate synthase
A1122_08110	COG0069	glutamate synthase activity
A1122_08115	COG1242	4 iron, 4 sulfur cluster binding
A1122_08125	COG2198	Histidine kinase
A1122_08125	COG0784	Response regulator, receiver
A1122_08125	COG5002	protein histidine kinase activity
A1122_08130	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A1122_08140	COG2823	Periplasmic or secreted lipoprotein
A1122_08160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A1122_08165	COG1741	Belongs to the pirin family
A1122_08170	COG0583	DNA-binding transcription factor activity
A1122_08175	COG0435	Glutathione S-transferase
A1122_08190	COG1073	alpha beta
A1122_08200	COG0360	Binds together with S18 to 16S ribosomal RNA
A1122_08210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A1122_08220	COG1943	Transposase
A1122_08230	COG3061	Opacity-associated protein A
A1122_08235	COG0545	Peptidyl-prolyl cis-trans isomerase
A1122_08245	COG0737	Belongs to the 5'-nucleotidase family
A1122_08255	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A1122_08265	COG1253	flavin adenine dinucleotide binding
A1122_08275	COG0729	surface antigen
A1122_08280	COG2911	Protein conserved in bacteria
A1122_08285	COG2105	PFAM AIG2 family protein
A1122_08290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A1122_08300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A1122_08325	COG3423	Transcriptional regulator
A1122_08335	COG0142	geranyltranstransferase activity
A1122_08350	COG0697	spore germination
A1122_08360	COG0642	Histidine kinase
A1122_08365	COG0745	RESPONSE REGULATOR receiver
A1122_08370	COG2027	D-alanyl-D-alanine carboxypeptidase
A1122_08375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A1122_08380	COG1534	Rna-binding protein
A1122_08390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A1122_08395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A1122_08405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A1122_08415	COG0195	Participates in both transcription termination and antitermination
A1122_08445	COG2801	Transposase and inactivated derivatives
A1122_08460	COG0513	Belongs to the DEAD box helicase family
A1122_08485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1122_08495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_08520	COG3153	acetyltransferase
A1122_08540	COG1653	transport
A1122_08550	COG0395	ABC-type sugar transport system, permease component
A1122_08555	COG3842	ATPase activity
A1122_08570	COG0702	epimerase
A1122_08575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A1122_08580	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
A1122_08585	COG3454	Phosphonate metabolism
A1122_08590	COG4778	phosphonate C-P lyase system protein PhnL
A1122_08595	COG4107	phosphonate C-P lyase system protein PhnK
A1122_08600	COG3627	carbon phosphorus lyase activity
A1122_08605	COG3626	phosphonate metabolism
A1122_08610	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
A1122_08615	COG3624	Phosphonate C-P lyase system protein PhnG
A1122_08620	COG2188	Transcriptional regulator
A1122_08635	COG4608	Belongs to the ABC transporter superfamily
A1122_08640	COG0444	Belongs to the ABC transporter superfamily
A1122_08645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_08650	COG0601	transmembrane transport
A1122_08670	COG2731	YhcH YjgK YiaL family protein
A1122_08675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A1122_08680	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
A1122_08690	COG0525	valine-tRNA ligase activity
A1122_08695	COG2927	DNA polymerase III (CHI subunit)
A1122_08705	COG0795	lipopolysaccharide-transporting ATPase activity
A1122_08710	COG0795	lipopolysaccharide-transporting ATPase activity
A1122_08715	COG0582	viral genome integration into host DNA
A1122_08740	COG1943	Transposase
A1122_08755	COG0237	dephospho-CoA kinase activity
A1122_08765	COG1459	type II secretion system
A1122_08770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A1122_08775	COG4969	Belongs to the N-Me-Phe pilin family
A1122_08785	COG3023	N-Acetylmuramoyl-L-alanine amidase
A1122_08790	COG3725	Membrane protein required for beta-lactamase induction
A1122_08795	COG1113	amino acid transport
A1122_08800	COG2186	Transcriptional regulator
A1122_08805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A1122_08810	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1122_08815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1122_08825	COG1943	Transposase
A1122_08830	COG1049	propionate catabolic process, 2-methylcitrate cycle
A1122_08840	COG0697	spore germination
A1122_08860	COG2132	Multicopper oxidase
A1122_08865	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A1122_08870	COG0288	reversible hydration of carbon dioxide
A1122_08875	COG1131	(ABC) transporter
A1122_08880	COG0842	Transport permease protein
A1122_08885	COG0726	polysaccharide deacetylase
A1122_08915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A1122_08920	COG0617	tRNA 3'-terminal CCA addition
A1122_08925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A1122_08935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A1122_08945	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A1122_08950	COG1643	Atp-dependent helicase
A1122_08955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A1122_08960	COG1120	ATPase activity
A1122_08965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1122_08970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_08995	COG2860	membrane
A1122_09005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A1122_09015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1122_09020	COG2205	protein histidine kinase activity
A1122_09020	COG3437	response regulator, receiver
A1122_09020	COG3850	Histidine kinase
A1122_09020	COG4999	Histidine kinase
A1122_09025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A1122_09030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A1122_09035	COG3956	TIGRFAM MazG family protein
A1122_09055	COG0602	queuosine metabolic process
A1122_09060	COG0720	synthase
A1122_09110	COG0529	Catalyzes the synthesis of activated sulfate
A1122_09125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A1122_09150	COG1388	LysM domain
A1122_09150	COG4942	peptidase
A1122_09155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A1122_09160	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A1122_09165	COG0698	ribose 5-phosphate isomerase
A1122_09170	COG1063	alcohol dehydrogenase
A1122_09175	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_09180	COG2376	Dihydroxyacetone kinase
A1122_09195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A1122_09215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_09220	COG1858	cytochrome C peroxidase
A1122_09250	COG0024	Methionine aminopeptidase
A1122_09260	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A1122_09260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A1122_09265	COG1070	Carbohydrate kinase
A1122_09270	COG3623	hexulose-6-phosphate isomerase
A1122_09275	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_09280	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_09285	COG1129	ABC transporter
A1122_09290	COG1943	Transposase
A1122_09300	COG1349	DNA-binding transcription factor activity
A1122_09305	COG0235	Class ii aldolase
A1122_09310	COG0243	molybdopterin cofactor binding
A1122_09315	COG0437	4 iron, 4 sulfur cluster binding
A1122_09320	COG3302	dmso reductase anchor subunit
A1122_09325	COG3381	protein complex oligomerization
A1122_09330	COG3038	cytochrome b561
A1122_09335	COG3783	Cytochrome b(562)
A1122_09355	COG1129	ABC transporter
A1122_09360	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_09365	COG3959	Transketolase, thiamine diphosphate binding domain
A1122_09370	COG3958	Transketolase
A1122_09375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A1122_09410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A1122_09415	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A1122_09420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_09425	COG1238	metal cluster binding
A1122_09430	COG2918	glutathione biosynthetic process
A1122_09445	COG1943	Transposase
A1122_09455	COG1943	Transposase
A1122_09460	COG4536	flavin adenine dinucleotide binding
A1122_09475	COG4536	flavin adenine dinucleotide binding
A1122_09480	COG4137	Cytochrome C assembly protein
A1122_09485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A1122_09510	COG1943	Transposase
A1122_09515	COG3137	Salt-induced outer membrane protein
A1122_09530	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1122_09535	COG3279	Response regulator of the LytR AlgR family
A1122_09540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A1122_09545	COG1605	Chorismate mutase
A1122_09545	COG0287	Prephenate dehydrogenase
A1122_09550	COG0077	Prephenate dehydratase
A1122_09550	COG1605	Chorismate mutase
A1122_09565	COG0077	Prephenate dehydratase
A1122_09565	COG1605	Chorismate mutase
A1122_09575	COG1943	Transposase
A1122_09580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A1122_09585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1122_09590	COG0564	pseudouridine synthase activity
A1122_09600	COG0542	response to heat
A1122_09610	COG5544	Lipoprotein
A1122_09615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1122_09620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1122_09620	COG0045	succinate-CoA ligase (ADP-forming) activity
A1122_09620	COG1042	CoA-binding domain protein
A1122_09630	COG3118	belongs to the thioredoxin family
A1122_09635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1122_09640	COG2814	Major facilitator Superfamily
A1122_09645	COG1566	PFAM secretion protein HlyD family protein
A1122_09650	COG1846	Transcriptional regulator
A1122_09660	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A1122_09665	COG2814	Major facilitator Superfamily
A1122_09710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A1122_09725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A1122_09755	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
A1122_09765	COG1960	acyl-CoA dehydrogenase activity
A1122_09775	COG0121	glutamine amidotransferase
A1122_09780	COG3034	peptidoglycan biosynthetic process
A1122_09785	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A1122_09790	COG1805	sodium ion transport
A1122_09795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A1122_09815	COG1477	protein flavinylation
A1122_09835	COG2195	Cleaves the N-terminal amino acid of tripeptides
A1122_09840	COG0583	DNA-binding transcription factor activity
A1122_09890	COG2226	methyltransferase
A1122_09915	COG1940	carbohydrate kinase activity
A1122_09930	COG0419	ATPase involved in DNA repair
A1122_09935	COG0420	3'-5' exonuclease activity
A1122_09940	COG0745	RESPONSE REGULATOR receiver
A1122_09945	COG5002	protein histidine kinase activity
A1122_09955	COG1114	Component of the transport system for branched-chain amino acids
A1122_09965	COG0366	Alpha amylase catalytic
A1122_09985	COG1943	Transposase
A1122_09990	COG0450	alkyl hydroperoxide reductase
A1122_09995	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
A1122_10000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A1122_10010	COG1862	Preprotein translocase
A1122_10015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A1122_10020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A1122_10025	COG1943	Transposase
A1122_10045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1122_10045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1122_10060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A1122_10065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A1122_10075	COG1943	Transposase
A1122_10085	COG0142	geranyltranstransferase activity
A1122_10100	COG0693	protein deglycase activity
A1122_10105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A1122_10115	COG2814	Major facilitator Superfamily
A1122_10125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A1122_10130	COG1845	cytochrome c oxidase, subunit III
A1122_10135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A1122_10140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A1122_10150	COG2223	nitrite transmembrane transporter activity
A1122_10155	COG3056	Lipoprotein
A1122_10160	COG0271	Belongs to the BolA IbaG family
A1122_10180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A1122_10185	COG0776	regulation of translation
A1122_10190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1122_10195	COG1555	photosystem II stabilization
A1122_10200	COG0824	Thioesterase
A1122_10210	COG4533	DNA binding
A1122_10225	COG1522	sequence-specific DNA binding
A1122_10230	COG1132	(ABC) transporter
A1122_10235	COG1132	(ABC) transporter
A1122_10240	COG0347	Belongs to the P(II) protein family
A1122_10245	COG0004	ammonium transporteR
A1122_10250	COG1946	Acyl-CoA thioesterase
A1122_10255	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A1122_10260	COG3695	enzyme binding
A1122_10280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A1122_10290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_10295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_10300	COG1309	transcriptional regulator
A1122_10305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A1122_10310	COG1196	nuclear chromosome segregation
A1122_10310	COG3264	Mechanosensitive ion channel
A1122_10325	COG2832	Protein of unknown function (DUF454)
A1122_10350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A1122_10380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_10380	COG0543	2 iron, 2 sulfur cluster binding
A1122_10405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_10440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A1122_10445	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A1122_10475	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A1122_10480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_10485	COG4651	solute:proton antiporter activity
A1122_10485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A1122_10490	COG2223	nitrite transmembrane transporter activity
A1122_10495	COG0737	Belongs to the 5'-nucleotidase family
A1122_10500	COG0737	Belongs to the 5'-nucleotidase family
A1122_10505	COG0737	Belongs to the 5'-nucleotidase family
A1122_10520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A1122_10525	COG3735	TraB family
A1122_10530	COG2217	Heavy metal translocating P-type atpase
A1122_10535	COG0789	Transcriptional regulator
A1122_10540	COG1585	Membrane protein implicated in regulation of membrane protease activity
A1122_10545	COG0330	HflC and HflK could
A1122_10550	COG3118	belongs to the thioredoxin family
A1122_10555	COG0300	oxidoreductase activity
A1122_10560	COG2755	lipolytic protein G-D-S-L family
A1122_10565	COG4181	ATPase activity
A1122_10570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A1122_10575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A1122_10580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A1122_10590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A1122_10605	COG1943	Transposase
A1122_10615	COG1393	Belongs to the ArsC family
A1122_10620	COG4783	chaperone-mediated protein folding
A1122_10625	COG0628	permease
A1122_10645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A1122_10650	COG2716	regulation of RNA biosynthetic process
A1122_10660	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A1122_10665	COG1943	Transposase
A1122_10675	COG2321	neutral zinc metallopeptidase
A1122_10695	COG1876	peptidase activity
A1122_10705	COG1393	Belongs to the ArsC family
A1122_10715	COG1840	ABC-type Fe3 transport system, periplasmic component
A1122_10720	COG1175	transmembrane transport
A1122_10725	COG3842	ATPase activity
A1122_10730	COG3119	arylsulfatase activity
A1122_10735	COG0641	radical SAM
A1122_10740	COG1988	membrane-bound metal-dependent
A1122_10750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_10760	COG2197	response regulator
A1122_10765	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_10765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_10770	COG3062	negative regulation of establishment of protein localization
A1122_10785	COG3043	anaerobic respiration
A1122_10790	COG3005	denitrification pathway
A1122_10830	COG3111	PFAM Bacterial OB fold (BOF) protein
A1122_10840	COG2837	iron assimilation
A1122_10845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A1122_10875	COG2731	YhcH YjgK YiaL family protein
A1122_10880	COG1737	Transcriptional regulator
A1122_10890	COG4150	thiosulfate binding
A1122_10895	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A1122_10900	COG4208	sulfate ABC transporter
A1122_10905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A1122_10920	COG0745	RESPONSE REGULATOR receiver
A1122_10925	COG3850	Histidine kinase
A1122_10925	COG5002	protein histidine kinase activity
A1122_10940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A1122_10950	COG0006	proline dipeptidase activity
A1122_10960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A1122_10975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_10980	COG0745	RESPONSE REGULATOR receiver
A1122_10985	COG2205	protein histidine kinase activity
A1122_10995	COG1943	Transposase
A1122_11000	COG2190	(PTS) system
A1122_11010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_11015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A1122_11020	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
A1122_11035	COG3530	Putative quorum-sensing-regulated virulence factor
A1122_11055	COG1943	Transposase
A1122_11065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1122_11080	COG0667	Aldo Keto reductase
A1122_11105	COG0436	Aminotransferase
A1122_11110	COG3038	cytochrome b561
A1122_11140	COG3381	protein complex oligomerization
A1122_11145	COG3302	dmso reductase anchor subunit
A1122_11150	COG0437	4 iron, 4 sulfur cluster binding
A1122_11155	COG0243	molybdopterin cofactor binding
A1122_11190	COG2951	lytic endotransglycosylase activity
A1122_11255	COG3121	Chaperone
A1122_11260	COG3188	usher protein
A1122_11265	COG3328	transposase activity
A1122_11270	COG3188	usher protein
A1122_11330	COG0671	phosphoesterase, PA-phosphatase related
A1122_11330	COG2453	phosphatase
A1122_11335	COG2267	carboxylic ester hydrolase activity
A1122_11345	COG4589	Belongs to the CDS family
A1122_11350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A1122_11410	COG2501	S4 domain
A1122_11415	COG1943	Transposase
A1122_11430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A1122_11435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1122_11455	COG0581	inorganic phosphate transmembrane transporter activity
A1122_11465	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A1122_11470	COG0248	Ppx GppA phosphatase
A1122_11480	COG2239	Acts as a magnesium transporter
A1122_11485	COG0443	Heat shock 70 kDa protein
A1122_11490	COG1177	transmembrane transport
A1122_11495	COG1176	ABC-type spermidine putrescine transport system, permease component I
A1122_11505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A1122_11515	COG3842	ATPase activity
A1122_11550	COG0745	RESPONSE REGULATOR receiver
A1122_11555	COG3422	double-strand break repair
A1122_11590	COG0351	phosphomethylpyrimidine kinase
A1122_11605	COG3328	transposase activity
A1122_11640	COG1943	Transposase
A1122_11660	COG0516	GMP reductase activity
A1122_11660	COG0517	IMP dehydrogenase activity
A1122_11670	COG1645	bacterial-type flagellum-dependent swarming motility
A1122_11685	COG1943	Transposase
A1122_11695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1122_11700	COG2976	Protein conserved in bacteria
A1122_11745	COG3468	outer membrane autotransporter barrel domain protein
A1122_11750	COG3468	outer membrane autotransporter barrel domain protein
A1122_11775	COG2975	iron-sulfur cluster assembly
A1122_11780	COG0633	Ferredoxin
A1122_11785	COG0443	Heat shock 70 kDa protein
A1122_11800	COG0822	iron-sulfur transferase activity
A1122_11805	COG1104	cysteine desulfurase activity
A1122_11820	COG0483	inositol monophosphate 1-phosphatase activity
A1122_11825	COG1943	Transposase
A1122_11830	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A1122_11835	COG3683	transport system, periplasmic component
A1122_11840	COG3711	transcriptional antiterminator
A1122_11845	COG2814	Major facilitator Superfamily
A1122_11860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_11860	COG1017	nitric oxide dioxygenase activity
A1122_11875	COG0347	Belongs to the P(II) protein family
A1122_11880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A1122_11880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1122_11890	COG2204	response regulator
A1122_11895	COG3170	Tfp pilus assembly protein FimV
A1122_11900	COG2205	protein histidine kinase activity
A1122_11905	COG1943	Transposase
A1122_11940	COG0590	tRNA wobble adenosine to inosine editing
A1122_11945	COG0560	Phosphoserine phosphatase
A1122_11955	COG1737	Transcriptional regulator
A1122_11960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_11965	COG1943	Transposase
A1122_11975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A1122_12000	COG0667	Aldo Keto reductase
A1122_12005	COG0656	L-ascorbic acid biosynthetic process
A1122_12045	COG3328	transposase activity
A1122_12050	COG2850	peptidyl-arginine hydroxylation
A1122_12105	COG3423	Transcriptional regulator
A1122_12110	COG4953	penicillin-binding protein 1C
A1122_12115	COG3328	transposase activity
A1122_12120	COG3037	sugar-specific permease SgaT UlaA
A1122_12125	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A1122_12135	COG0622	Phosphoesterase
A1122_12145	COG1090	epimerase
A1122_12150	COG4598	ABC transporter
A1122_12155	COG4160	amino acid transport
A1122_12160	COG4215	(ABC) transporter
A1122_12165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_12170	COG0163	prenyltransferase activity
A1122_12175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A1122_12180	COG1286	toxin biosynthetic process
A1122_12185	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A1122_12190	COG0285	dihydrofolate synthase activity
A1122_12200	COG0586	Pfam SNARE associated Golgi protein
A1122_12210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A1122_12215	COG1943	Transposase
A1122_12235	COG0697	spore germination
A1122_12250	COG1794	racemase activity, acting on amino acids and derivatives
A1122_12260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_12275	COG3101	peptidyl-lysine hydroxylation
A1122_12280	COG0730	response to heat
A1122_12285	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
A1122_12295	COG2890	protein-(glutamine-N5) methyltransferase activity
A1122_12305	COG2062	phosphohistidine phosphatase, SixA
A1122_12320	COG3691	Protein conserved in bacteria
A1122_12335	COG3088	subunit of a heme lyase
A1122_12335	COG4235	cytochrome complex assembly
A1122_12340	COG3088	subunit of a heme lyase
A1122_12340	COG4235	cytochrome complex assembly
A1122_12345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1122_12350	COG1138	Cytochrome C-type biogenesis protein
A1122_12360	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1122_12365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1122_12370	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1122_12385	COG1704	LemA family
A1122_12395	COG2824	Alkylphosphonate utilization operon protein PhnA
A1122_12420	COG3501	Rhs element vgr protein
A1122_12465	COG0681	Belongs to the peptidase S26 family
A1122_12480	COG3086	response to oxidative stress
A1122_12485	COG3026	antisigma factor binding
A1122_12490	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
A1122_12500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A1122_12510	COG0513	Belongs to the DEAD box helicase family
A1122_12560	COG1984	allophanate hydrolase subunit 2
A1122_12565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A1122_12570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A1122_12575	COG5212	phosphodiesterase
A1122_12585	COG3272	Protein of unknown function (DUF1722)
A1122_12620	COG2205	protein histidine kinase activity
A1122_12625	COG0745	RESPONSE REGULATOR receiver
A1122_12645	COG0033	Phosphoglucomutase
A1122_12650	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
A1122_12670	COG1917	Cupin 2, conserved barrel domain protein
A1122_12670	COG2169	Transcriptional regulator
A1122_12675	COG1447	Phosphotransferase system cellobiose-specific component IIA
A1122_12680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1122_12685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1122_12695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A1122_12700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A1122_12705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A1122_12720	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A1122_12725	COG4413	Urea transporter
A1122_12740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A1122_12770	COG1124	(ABC) transporter
A1122_12775	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A1122_12780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_12790	COG0747	negative chemotaxis
A1122_12795	COG1278	Cold shock
A1122_12805	COG3328	transposase activity
A1122_12845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A1122_12850	COG4175	Glycine betaine
A1122_12855	COG4176	ABC-type proline glycine betaine transport system permease component
A1122_12860	COG2113	Glycine betaine
A1122_12885	COG0582	viral genome integration into host DNA
A1122_12890	COG2963	transposase activity
A1122_12905	COG0596	Alpha beta hydrolase
A1122_12925	COG0735	belongs to the Fur family
A1122_12950	COG1943	Transposase
A1122_12955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_12955	COG1263	PTS System
A1122_12955	COG2190	(PTS) system
A1122_12965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A1122_12970	COG1940	carbohydrate kinase activity
A1122_12970	COG1846	Transcriptional regulator
A1122_12975	COG0647	UMP catabolic process
A1122_12980	COG0367	asparagine synthase
A1122_12995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1122_13005	COG1702	phosphate starvation-inducible protein PhoH
A1122_13015	COG4535	Mg2 and Co2 transporter CorC
A1122_13020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A1122_13030	COG0765	amino acid transport
A1122_13035	COG0765	amino acid transport
A1122_13040	COG1126	abc transporter atp-binding protein
A1122_13045	COG2888	peptidyl-tyrosine sulfation
A1122_13060	COG1466	dna polymerase III delta subunit
A1122_13070	COG0799	negative regulation of ribosome biogenesis
A1122_13080	COG0768	penicillin binding
A1122_13085	COG0772	Belongs to the SEDS family
A1122_13090	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A1122_13095	COG1686	Belongs to the peptidase S11 family
A1122_13115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A1122_13125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A1122_13130	COG1278	Cold shock
A1122_13145	COG2197	response regulator
A1122_13170	COG5265	(ABC) transporter
A1122_13180	COG3718	enzyme involved in inositol metabolism
A1122_13190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_13195	COG0673	inositol 2-dehydrogenase activity
A1122_13200	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_13205	COG1129	ABC transporter
A1122_13210	COG1879	ABC-type sugar transport system periplasmic component
A1122_13215	COG0673	inositol 2-dehydrogenase activity
A1122_13220	COG0673	inositol 2-dehydrogenase activity
A1122_13225	COG3962	Belongs to the TPP enzyme family
A1122_13250	COG2373	Large extracellular alpha-helical protein
A1122_13255	COG4953	penicillin-binding protein 1C
A1122_13260	COG3328	transposase activity
A1122_13275	COG1609	Transcriptional regulator
A1122_13285	COG0280	phosphate acetyltransferase
A1122_13285	COG0857	belongs to the CobB CobQ family
A1122_13305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_13310	COG0471	metal ion transport
A1122_13310	COG0490	domain, Protein
A1122_13325	COG0436	Aminotransferase
A1122_13335	COG0583	DNA-binding transcription factor activity
A1122_13345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1122_13355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A1122_13365	COG1034	ATP synthesis coupled electron transport
A1122_13380	COG0839	Belongs to the complex I subunit 6 family
A1122_13390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A1122_13395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1122_13410	COG2731	YhcH YjgK YiaL family protein
A1122_13415	COG3265	gluconokinase activity
A1122_13420	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_13435	COG1609	Transcriptional regulator
A1122_13445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A1122_13465	COG0129	dihydroxy-acid dehydratase activity
A1122_13475	COG4575	ribosome binding
A1122_13485	COG1169	isochorismate synthase
A1122_13500	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A1122_13515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A1122_13565	COG1126	abc transporter atp-binding protein
A1122_13570	COG0765	amino acid transport
A1122_13575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_13605	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A1122_13625	COG1063	alcohol dehydrogenase
A1122_13630	COG1879	ABC-type sugar transport system periplasmic component
A1122_13635	COG1129	ABC transporter
A1122_13640	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_13645	COG1609	Transcriptional regulator
A1122_13650	COG0583	DNA-binding transcription factor activity
A1122_13655	COG0473	3-isopropylmalate dehydrogenase activity
A1122_13665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A1122_13670	COG4638	Rieske (2fe-2S)
A1122_13675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_13680	COG2831	hemolysin activation secretion protein
A1122_13685	COG3210	domain, Protein
A1122_13705	COG3210	domain, Protein
A1122_13730	COG3210	domain, Protein
A1122_13740	COG3842	ATPase activity
A1122_13750	COG1609	Transcriptional regulator
A1122_13765	COG0395	ABC-type sugar transport system, permease component
A1122_13770	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
A1122_13790	COG0668	transmembrane transport
A1122_13800	COG1518	maintenance of DNA repeat elements
A1122_13805	COG1203	CRISPR-associated helicase, Cas3
A1122_13835	COG0667	Aldo Keto reductase
A1122_13845	COG0477	Major facilitator Superfamily
A1122_13855	COG0583	DNA-binding transcription factor activity
A1122_13860	COG2771	luxR family
A1122_13865	COG3916	Acyl-homoserine-lactone synthase
A1122_13890	COG0628	permease
A1122_13905	COG3328	transposase activity
A1122_13910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_13930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1122_13935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1122_13940	COG1121	(ABC) transporter
A1122_13945	COG0803	Belongs to the bacterial solute-binding protein 9 family
A1122_13965	COG4249	Peptidase C14 caspase catalytic subunit p20
A1122_13995	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A1122_14000	COG0072	phenylalanine-tRNA ligase activity
A1122_14000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A1122_14005	COG0776	regulation of translation
A1122_14020	COG0386	Belongs to the glutathione peroxidase family
A1122_14025	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
A1122_14065	COG0791	NLP P60 protein
A1122_14095	COG0574	Belongs to the PEP-utilizing enzyme family
A1122_14095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A1122_14100	COG0628	permease
A1122_14110	COG0277	FAD linked oxidase domain protein
A1122_14110	COG0247	lactate metabolic process
A1122_14115	COG2050	protein possibly involved in aromatic compounds catabolism
A1122_14120	COG0316	Belongs to the HesB IscA family
A1122_14125	COG0719	Fe-S assembly protein
A1122_14130	COG0396	ATPase activity
A1122_14135	COG0719	Fe-S assembly protein
A1122_14150	COG1388	LysM domain
A1122_14150	COG1376	ErfK ybiS ycfS ynhG family protein
A1122_14165	COG1943	Transposase
A1122_14170	COG4238	major outer membrane lipoprotein
A1122_14185	COG0307	riboflavin synthase, alpha
A1122_14190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A1122_14195	COG2814	Major facilitator Superfamily
A1122_14200	COG0583	DNA-binding transcription factor activity
A1122_14210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A1122_14215	COG0791	NLP P60 protein
A1122_14220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A1122_14230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A1122_14235	COG0346	lactoylglutathione lyase activity
A1122_14245	COG1902	pentaerythritol trinitrate reductase activity
A1122_14250	COG1309	transcriptional regulator
A1122_14255	COG2194	sulfuric ester hydrolase activity
A1122_14260	COG3313	Fe-S protein
A1122_14265	COG4989	oxidoreductase activity
A1122_14275	COG3133	Outer membrane lipoprotein
A1122_14285	COG3895	Periplasmic Protein
A1122_14305	COG0625	glutathione transferase activity
A1122_14330	COG3104	oligopeptide transport
A1122_14335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1122_14335	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1122_14340	COG4172	Belongs to the ABC transporter superfamily
A1122_14350	COG4171	peptide transport system, permease
A1122_14355	COG4168	peptide transport system, permease
A1122_14360	COG4166	transmembrane transport
A1122_14370	COG1943	Transposase
A1122_14375	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A1122_14380	COG1842	Phage shock protein A
A1122_14390	COG1983	PspC domain protein
A1122_14400	COG3106	COG3106 Predicted ATPase
A1122_14425	COG1943	Transposase
A1122_14430	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A1122_14435	COG4948	Mandelate Racemase Muconate Lactonizing
A1122_14440	COG2866	Carboxypeptidase
A1122_14445	COG4166	transmembrane transport
A1122_14465	COG2755	lipolytic protein G-D-S-L family
A1122_14465	COG0657	acetylesterase activity
A1122_14475	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1122_14475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A1122_14475	COG1013	pyruvate-flavodoxin oxidoreductase activity
A1122_14475	COG0674	pyruvate-flavodoxin oxidoreductase activity
A1122_14485	COG1285	pathogenesis
A1122_14490	COG3042	response to heat
A1122_14495	COG3187	Heat shock protein
A1122_14500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A1122_14505	COG2911	Protein conserved in bacteria
A1122_14515	COG3784	Protein of unknown function (DUF1318)
A1122_14520	COG0246	Mannitol dehydrogenase
A1122_14525	COG2390	Transcriptional regulator
A1122_14535	COG1643	Atp-dependent helicase
A1122_14550	COG3591	Belongs to the peptidase S1B family
A1122_14560	COG3038	cytochrome b561
A1122_14590	COG1943	Transposase
A1122_14595	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A1122_14600	COG2205	protein histidine kinase activity
A1122_14605	COG0745	RESPONSE REGULATOR receiver
A1122_14615	COG0531	amino acid
A1122_14625	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A1122_14630	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A1122_14635	COG0589	response to stress
A1122_14640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A1122_14645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A1122_14665	COG1011	Hydrolase
A1122_14670	COG0440	acetolactate synthase activity
A1122_14675	COG0028	Belongs to the TPP enzyme family
A1122_14700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A1122_14705	COG1116	anion transmembrane transporter activity
A1122_14710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1122_14715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A1122_14720	COG1879	ABC-type sugar transport system periplasmic component
A1122_14730	COG1609	Transcriptional regulator
A1122_14745	COG4128	Pfam Zonular occludens toxin
A1122_14795	COG0038	chloride channel
A1122_14800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A1122_14805	COG1940	carbohydrate kinase activity
A1122_14810	COG0583	DNA-binding transcription factor activity
A1122_14815	COG2814	Major facilitator Superfamily
A1122_14825	COG0114	fumarate hydratase activity
A1122_14835	COG5339	Protein conserved in bacteria
A1122_14845	COG0385	Bile acid
A1122_14850	COG0673	inositol 2-dehydrogenase activity
A1122_14860	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_14870	COG1879	ABC-type sugar transport system periplasmic component
A1122_14890	COG2274	protein secretion by the type I secretion system
A1122_14895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_14905	COG1132	(ABC) transporter
A1122_14935	COG3708	Transcriptional regulator
A1122_14935	COG2207	Transcriptional regulator
A1122_14940	COG4658	electron transport chain
A1122_14945	COG4659	FMN binding
A1122_14955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A1122_14960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_14965	COG2271	Major facilitator Superfamily
A1122_14975	COG1966	Carbon starvation protein
A1122_14980	COG2879	small protein
A1122_14985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A1122_15005	COG0023	Translation Initiation Factor
A1122_15020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A1122_15025	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A1122_15030	COG0671	phosphoesterase, PA-phosphatase related
A1122_15035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A1122_15040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A1122_15050	COG0583	DNA-binding transcription factor activity
A1122_15055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A1122_15070	COG0616	signal peptide processing
A1122_15075	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_15085	COG1187	pseudouridine synthase activity
A1122_15090	COG0009	L-threonylcarbamoyladenylate synthase
A1122_15105	COG0512	Glutamine amidotransferase of anthranilate synthase
A1122_15115	COG0135	phosphoribosylanthranilate isomerase activity
A1122_15115	COG0134	indole-3-glycerol-phosphate synthase activity
A1122_15135	COG3047	cAMP biosynthetic process
A1122_15165	COG1607	acyl-coa hydrolase
A1122_15170	COG3328	transposase activity
A1122_15175	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A1122_15180	COG2350	Protein conserved in bacteria
A1122_15225	COG4608	Belongs to the ABC transporter superfamily
A1122_15230	COG0444	Belongs to the ABC transporter superfamily
A1122_15235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_15240	COG0601	transmembrane transport
A1122_15250	COG2095	MarC family integral membrane protein
A1122_15255	COG1012	belongs to the aldehyde dehydrogenase family
A1122_15255	COG1454	alcohol dehydrogenase
A1122_15270	COG1435	thymidine kinase activity
A1122_15275	COG2916	Histone family protein nucleoid-structuring protein H-NS
A1122_15285	COG0745	RESPONSE REGULATOR receiver
A1122_15295	COG0788	formyltetrahydrofolate deformylase activity
A1122_15300	COG3328	transposase activity
A1122_15310	COG0583	DNA-binding transcription factor activity
A1122_15315	COG0708	Exodeoxyribonuclease III
A1122_15320	COG0494	nUDIX hydrolase
A1122_15330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A1122_15335	COG0709	Synthesizes selenophosphate from selenide and ATP
A1122_15340	COG0778	Nitroreductase
A1122_15345	COG0616	signal peptide processing
A1122_15350	COG0252	asparaginase activity
A1122_15355	COG1335	isochorismatase
A1122_15360	COG3139	Protein of unknown function (DUF1315)
A1122_15380	COG3713	MltA-interacting MipA family protein
A1122_15385	COG2766	serine protein kinase
A1122_15400	COG0583	DNA-binding transcription factor activity
A1122_15410	COG2814	Major facilitator Superfamily
A1122_15420	COG2719	SpoVR family
A1122_15450	COG1104	cysteine desulfurase activity
A1122_15460	COG3328	transposase activity
A1122_15535	COG1943	Transposase
A1122_15620	COG3328	transposase activity
A1122_15720	COG0582	viral genome integration into host DNA
A1122_15730	COG0179	Fumarylacetoacetate (FAA) hydrolase
A1122_15755	COG2894	cell division
A1122_15760	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A1122_15765	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A1122_15770	COG0318	PFAM AMP-dependent synthetase and ligase
A1122_15795	COG1199	ATP-dependent helicase activity
A1122_15800	COG0251	oxidation-reduction process
A1122_15815	COG0800	Aldolase
A1122_15825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A1122_15830	COG1737	Transcriptional regulator
A1122_15835	COG0469	pyruvate kinase activity
A1122_15845	COG1560	Kdo2-lipid A biosynthetic process
A1122_15850	COG0739	heme binding
A1122_15855	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A1122_15865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1122_15890	COG0494	nUDIX hydrolase
A1122_15900	COG1801	Protein of unknown function DUF72
A1122_15905	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A1122_15925	COG3102	Protein conserved in bacteria
A1122_15945	COG0728	peptidoglycan biosynthetic process
A1122_15950	COG0673	inositol 2-dehydrogenase activity
A1122_15955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1122_15975	COG3381	protein complex oligomerization
A1122_15985	COG1940	carbohydrate kinase activity
A1122_15990	COG0584	glycerophosphoryl diester phosphodiesterase
A1122_15995	COG3842	ATPase activity
A1122_16000	COG1943	Transposase
A1122_16010	COG1176	ABC-type spermidine putrescine transport system, permease component I
A1122_16015	COG3833	ABC-type maltose transport systems, permease component
A1122_16030	COG0659	secondary active sulfate transmembrane transporter activity
A1122_16045	COG0659	secondary active sulfate transmembrane transporter activity
A1122_16050	COG1943	Transposase
A1122_16065	COG2912	Transglutaminase-like superfamily
A1122_16070	COG3094	Invasion gene expression up-regulator, SirB
A1122_16075	COG2890	protein-(glutamine-N5) methyltransferase activity
A1122_16105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A1122_16125	COG0012	GTP binding
A1122_16180	COG5002	protein histidine kinase activity
A1122_16225	COG0500	methyltransferase
A1122_16245	COG3328	transposase activity
A1122_16290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_16295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A1122_16300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A1122_16315	COG0402	S-adenosylhomocysteine deaminase activity
A1122_16335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A1122_16375	COG0395	ABC-type sugar transport system, permease component
A1122_16380	COG1175	transmembrane transport
A1122_16390	COG0673	inositol 2-dehydrogenase activity
A1122_16430	COG3328	transposase activity
A1122_16435	COG3328	transposase activity
A1122_16540	COG2197	response regulator
A1122_16550	COG3136	membrane protein required for alginate biosynthesis
A1122_16565	COG1113	amino acid transport
A1122_16580	COG2837	iron assimilation
A1122_16600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A1122_16600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A1122_16600	COG0506	proline dehydrogenase activity
A1122_16640	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A1122_16650	COG1191	sigma factor activity
A1122_16680	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A1122_16685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A1122_16690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A1122_16705	COG1677	Flagellar hook-basal body complex protein FliE
A1122_16715	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A1122_16725	COG1157	protein secretion by the type III secretion system
A1122_16730	COG2882	bacterial-type flagellum organization
A1122_16740	COG1580	Controls the rotational direction of flagella during chemotaxis
A1122_16765	COG1987	bacterial-type flagellum assembly
A1122_16785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_16790	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_16795	COG1129	ABC transporter
A1122_16805	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_16810	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_16810	COG3347	Dehydrogenase
A1122_16815	COG2390	Transcriptional regulator
A1122_16825	COG1256	bacterial-type flagellum assembly
A1122_16845	COG4786	Flagellar basal body rod
A1122_16855	COG1749	Flagellar hook protein flgE
A1122_16860	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A1122_16865	COG1558	bacterial-type flagellum-dependent cell motility
A1122_16870	COG1815	bacterial-type flagellum-dependent cell motility
A1122_16880	COG2747	anti-sigma28 factor FlgM
A1122_16885	COG3418	PFAM FlgN family protein
A1122_16895	COG1943	Transposase
A1122_16910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1122_16915	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1122_16940	COG2372	response to copper ion
A1122_16945	COG1528	Iron-storage protein
A1122_16965	COG1770	oligopeptidase
A1122_16980	COG3141	response to X-ray
A1122_16985	COG0513	Belongs to the DEAD box helicase family
A1122_17010	COG1760	l-serine dehydratase
A1122_17015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A1122_17020	COG2368	4-hydroxyphenylacetate
A1122_17035	COG3971	2-oxopent-4-enoate hydratase activity
A1122_17045	COG3384	dioxygenase
A1122_17050	COG1012	belongs to the aldehyde dehydrogenase family
A1122_17065	COG1846	Transcriptional regulator
A1122_17070	COG1253	flavin adenine dinucleotide binding
A1122_17075	COG1253	flavin adenine dinucleotide binding
A1122_17080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_17080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_17085	COG3715	PTS system
A1122_17090	COG3716	PTS system mannose fructose sorbose family IID component
A1122_17115	COG3447	MASE1 domain protein
A1122_17115	COG5001	Diguanylate cyclase
A1122_17115	COG5002	protein histidine kinase activity
A1122_17125	COG2226	methyltransferase
A1122_17135	COG1278	Cold shock
A1122_17150	COG1113	amino acid transport
A1122_17190	COG2207	Transcriptional regulator
A1122_17205	COG1132	(ABC) transporter
A1122_17245	COG3328	transposase activity
A1122_17250	COG1917	Cupin 2, conserved barrel domain protein
A1122_17260	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_17270	COG1175	transmembrane transport
A1122_17275	COG0395	ABC-type sugar transport system, permease component
A1122_17280	COG3842	ATPase activity
A1122_17285	COG1653	transport
A1122_17290	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A1122_17295	COG1988	membrane-bound metal-dependent
A1122_17305	COG3023	N-Acetylmuramoyl-L-alanine amidase
A1122_17315	COG0823	Involved in the tonB-independent uptake of proteins
A1122_17320	COG2814	Major facilitator Superfamily
A1122_17325	COG3121	Chaperone
A1122_17340	COG3121	Chaperone
A1122_17345	COG3539	Fimbrial protein
A1122_17355	COG0793	Belongs to the peptidase S41A family
A1122_17365	COG1956	GAF domain-containing protein
A1122_17370	COG2995	paraquat-inducible protein a
A1122_17375	COG3008	intermembrane lipid transfer
A1122_17395	COG3121	Chaperone
A1122_17450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A1122_17460	COG5295	Hep Hag repeat protein
A1122_17470	COG3023	N-Acetylmuramoyl-L-alanine amidase
A1122_17475	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
A1122_17480	COG0745	RESPONSE REGULATOR receiver
A1122_17490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A1122_17505	COG0840	transmembrane signaling receptor activity
A1122_17525	COG2964	Protein conserved in bacteria
A1122_17535	COG0251	oxidation-reduction process
A1122_17540	COG2271	Major facilitator Superfamily
A1122_17545	COG0835	chemotaxis
A1122_17550	COG0643	Histidine kinase
A1122_17550	COG2198	Histidine kinase
A1122_17555	COG1360	Flagellar Motor Protein
A1122_17580	COG1285	pathogenesis
A1122_17585	COG0840	transmembrane signaling receptor activity
A1122_17590	COG0840	transmembrane signaling receptor activity
A1122_17600	COG1278	Cold shock
A1122_17610	COG3321	synthase
A1122_17610	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_17610	COG0604	alcohol dehydrogenase
A1122_17620	COG1522	sequence-specific DNA binding
A1122_17650	COG1733	regulation of RNA biosynthetic process
A1122_17655	COG0702	epimerase
A1122_17660	COG0840	transmembrane signaling receptor activity
A1122_17675	COG0538	isocitrate dehydrogenase activity
A1122_17680	COG1187	pseudouridine synthase activity
A1122_17700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A1122_17710	COG0745	RESPONSE REGULATOR receiver
A1122_17720	COG2850	peptidyl-arginine hydroxylation
A1122_17730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A1122_17745	COG4591	ABC-type transport system involved in lipoprotein release permease component
A1122_17755	COG4591	ABC-type transport system involved in lipoprotein release permease component
A1122_17760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A1122_17765	COG3134	Outer membrane lipoprotein
A1122_17780	COG3328	transposase activity
A1122_17795	COG1252	NADH dehydrogenase
A1122_17805	COG1472	Belongs to the glycosyl hydrolase 3 family
A1122_17820	COG5633	Lipoprotein
A1122_17825	COG0537	adenosine 5'-monophosphoramidase activity
A1122_17830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A1122_17835	COG1943	Transposase
A1122_17840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_17840	COG1263	PTS System
A1122_17845	COG0084	hydrolase, TatD family'
A1122_17850	COG0470	DNA polymerase III
A1122_17860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A1122_17870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1122_17875	COG1943	Transposase
A1122_17880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_17890	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_17910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A1122_17915	COG1399	metal-binding, possibly nucleic acid-binding protein
A1122_17925	COG1943	Transposase
A1122_17930	COG0564	pseudouridine synthase activity
A1122_17935	COG1530	ribonuclease E activity
A1122_17940	COG3328	transposase activity
A1122_17950	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A1122_17970	COG3328	transposase activity
A1122_17975	COG2223	nitrite transmembrane transporter activity
A1122_18000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A1122_18020	COG3122	Protein conserved in bacteria
A1122_18040	COG0534	Mate efflux family protein
A1122_18060	COG4948	Mandelate Racemase Muconate Lactonizing
A1122_18070	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_18075	COG3011	Protein conserved in bacteria
A1122_18080	COG2271	Major facilitator Superfamily
A1122_18085	COG1470	cell adhesion involved in biofilm formation
A1122_18085	COG1388	LysM domain
A1122_18090	COG3328	transposase activity
A1122_18110	COG2925	Exonuclease
A1122_18115	COG0531	amino acid
A1122_18125	COG0371	Dehydrogenase
A1122_18130	COG1129	ABC transporter
A1122_18135	COG1129	ABC transporter
A1122_18140	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_18150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_18160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A1122_18170	COG0131	Imidazoleglycerol-phosphate dehydratase
A1122_18170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A1122_18175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A1122_18190	COG0140	phosphoribosyl-ATP diphosphatase activity
A1122_18190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A1122_18200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A1122_18205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A1122_18225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1122_18230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_18235	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_18240	COG1120	ATPase activity
A1122_18255	COG3486	L-lysine 6-monooxygenase (NADPH) activity
A1122_18260	COG0076	glutamate decarboxylase activity
A1122_18265	COG4114	ferric iron reductase
A1122_18270	COG1253	flavin adenine dinucleotide binding
A1122_18275	COG2982	Protein involved in outer membrane biogenesis
A1122_18290	COG0489	protein tyrosine kinase activity
A1122_18300	COG1943	Transposase
A1122_18335	COG2814	Major facilitator Superfamily
A1122_18345	COG1346	cytolysis
A1122_18360	COG2949	membrane
A1122_18365	COG4211	Belongs to the binding-protein-dependent transport system permease family
A1122_18385	COG2311	Membrane
A1122_18395	COG0477	Major facilitator Superfamily
A1122_18400	COG0583	DNA-binding transcription factor activity
A1122_18430	COG1136	(ABC) transporter
A1122_18440	COG0303	'Molybdopterin
A1122_18450	COG3328	transposase activity
A1122_18460	COG0488	(ABC) transporter
A1122_18605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A1122_18610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1122_18620	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_18625	COG1024	Enoyl-CoA hydratase
A1122_18635	COG3425	synthase
A1122_18640	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_18645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_18650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A1122_18660	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_18695	COG2920	part of a sulfur-relay system
A1122_18715	COG1832	CoA-binding protein
A1122_18720	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A1122_18730	COG0210	DNA helicase
A1122_18735	COG3304	Inner membrane component domain
A1122_18740	COG1289	transmembrane transporter activity
A1122_18745	COG3070	regulator of competence-specific genes
A1122_18755	COG2885	chlorophyll binding
A1122_18755	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A1122_18765	COG1943	Transposase
A1122_18775	COG1067	ATP-dependent peptidase activity
A1122_18785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_18800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_18835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_18840	COG1120	ATPase activity
A1122_18865	COG4160	amino acid transport
A1122_18870	COG4215	(ABC) transporter
A1122_18875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_18880	COG1126	abc transporter atp-binding protein
A1122_18885	COG1605	Chorismate mutase
A1122_18895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_18900	COG0702	epimerase
A1122_18905	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A1122_18910	COG0028	Belongs to the TPP enzyme family
A1122_18915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_18925	COG2431	L-lysine efflux transmembrane transporter activity
A1122_18930	COG3593	DNA synthesis involved in DNA repair
A1122_18935	COG2990	Protein conserved in bacteria
A1122_18940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_18950	COG1278	Cold shock
A1122_18960	COG0542	response to heat
A1122_18965	COG1943	Transposase
A1122_18970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A1122_18980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A1122_18995	COG0492	ferredoxin-NADP+ reductase activity
A1122_19005	COG1674	ftsk spoiiie
A1122_19005	COG3107	peptidoglycan biosynthetic process
A1122_19015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A1122_19025	COG2814	Major facilitator Superfamily
A1122_19030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A1122_19040	COG1882	Formate acetyltransferase
A1122_19045	COG2116	formate transmembrane transporter activity
A1122_19050	COG1944	ATP diphosphatase activity
A1122_19055	COG0252	asparaginase activity
A1122_19060	COG5295	Hep Hag repeat protein
A1122_19060	COG5295	Hep Hag repeat protein
A1122_19085	COG0539	negative regulation of cytoplasmic translation
A1122_19100	COG2333	competence protein COMEC
A1122_19100	COG0658	competence protein
A1122_19115	COG5383	Protein conserved in bacteria
A1122_19125	COG1278	Cold shock
A1122_19130	COG2835	tetraacyldisaccharide 4'-kinase activity
A1122_19140	COG3173	Aminoglycoside phosphotransferase
A1122_19150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A1122_19155	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
A1122_19160	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A1122_19175	COG1943	Transposase
A1122_19180	COG2989	Protein conserved in bacteria
A1122_19185	COG3108	Peptidase M15
A1122_19190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1122_19200	COG1448	Aminotransferase
A1122_19220	COG0308	aminopeptidase N
A1122_19235	COG3217	Mosc domain protein beta barrel domain protein
A1122_19235	COG0633	Ferredoxin
A1122_19245	COG0488	(ABC) transporter
A1122_19250	COG2995	paraquat-inducible protein a
A1122_19255	COG3008	intermembrane lipid transfer
A1122_19255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A1122_19260	COG3009	Protein conserved in bacteria
A1122_19265	COG3130	regulation of translation
A1122_19275	COG1943	Transposase
A1122_19280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_19300	COG3657	addiction module killer protein
A1122_19345	COG0582	viral genome integration into host DNA
A1122_19350	COG1943	Transposase
A1122_19365	COG2867	negative regulation of translational initiation
A1122_19375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1122_19380	COG0497	DNA recombination
A1122_19385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A1122_19400	COG2009	succinate dehydrogenase
A1122_19405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A1122_19410	COG1053	succinate dehydrogenase
A1122_19420	COG0567	Dehydrogenase, E1 component
A1122_19425	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1122_19435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A1122_19440	COG1271	oxidase subunit
A1122_19445	COG1294	oxidase, subunit
A1122_19450	COG4890	Cyd operon protein YbgT
A1122_19455	COG3790	cyd operon protein YbgE
A1122_19460	COG0824	Thioesterase
A1122_19465	COG0811	peptide transport
A1122_19470	COG0848	biopolymer transport protein
A1122_19475	COG3064	Membrane
A1122_19475	COG3064	Membrane
A1122_19485	COG2885	chlorophyll binding
A1122_19490	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A1122_19510	COG1230	cation diffusion facilitator family transporter
A1122_19515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A1122_19530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A1122_19545	COG2017	converts alpha-aldose to the beta-anomer
A1122_19560	COG1085	galactose-1-phosphate uridylyltransferase
A1122_19565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A1122_19580	COG1119	ATPase activity
A1122_19585	COG2005	Transcriptional regulator
A1122_19585	COG3585	molybdate ion transport
A1122_19595	COG0725	ABC transporter, periplasmic molybdate-binding protein
A1122_19600	COG4149	molybdate abc transporter
A1122_19610	COG0561	phosphatase activity
A1122_19635	COG2226	methyltransferase
A1122_19640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A1122_19655	COG0556	nucleotide-excision repair
A1122_19660	COG4628	conserved protein (DUF2132)
A1122_19665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A1122_19675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A1122_19685	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A1122_19690	COG0314	molybdopterin synthase activity
A1122_19695	COG0670	Belongs to the BI1 family
A1122_19705	COG1943	Transposase
A1122_19725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A1122_19730	COG0583	DNA-binding transcription factor activity
A1122_19740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A1122_19745	COG2211	Major facilitator Superfamily
A1122_19750	COG1943	Transposase
A1122_19760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1122_19770	COG1686	Belongs to the peptidase S11 family
A1122_19775	COG0277	FAD linked oxidase domain protein
A1122_19785	COG1403	HNH endonuclease
A1122_19795	COG2261	transglycosylase associated protein
A1122_19805	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
A1122_19820	COG4807	Protein conserved in bacteria
A1122_19840	COG1122	ATPase activity
A1122_19845	COG0410	ABC transporter
A1122_19860	COG2897	thiosulfate sulfurtransferase activity
A1122_19875	COG1174	glycine betaine transport
A1122_19880	COG1125	glycine betaine transport
A1122_19885	COG1174	glycine betaine transport
A1122_19895	COG0531	amino acid
A1122_19900	COG1982	Orn Lys Arg decarboxylase major
A1122_19910	COG0697	spore germination
A1122_19935	COG0814	amino acid
A1122_19950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_19980	COG0784	Response regulator, receiver
A1122_19980	COG2205	protein histidine kinase activity
A1122_19990	COG0642	Histidine kinase
A1122_19990	COG2198	Histidine kinase
A1122_19995	COG2198	Histidine kinase
A1122_19995	COG0642	Histidine kinase
A1122_20000	COG2223	nitrite transmembrane transporter activity
A1122_20010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A1122_20015	COG1943	Transposase
A1122_20020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A1122_20065	COG3395	kinase activity
A1122_20070	COG0235	Class ii aldolase
A1122_20075	COG1349	DNA-binding transcription factor activity
A1122_20080	COG3622	Belongs to the hyi family
A1122_20100	COG4386	tail sheath protein
A1122_20145	COG3299	homolog of phage Mu protein gp47
A1122_20165	COG1737	Transcriptional regulator
A1122_20175	COG2723	6-phospho-beta-galactosidase activity
A1122_20195	COG3157	Type VI secretion system effector, Hcp
A1122_20210	COG3083	sulfuric ester hydrolase activity
A1122_20215	COG3082	Protein of unknown function (DUF1414)
A1122_20225	COG1943	Transposase
A1122_20235	COG1061	Type III restriction enzyme res subunit
A1122_20240	COG1187	pseudouridine synthase activity
A1122_20245	COG2814	Major facilitator Superfamily
A1122_20255	COG4172	Belongs to the ABC transporter superfamily
A1122_20260	COG4239	(ABC) transporter, permease
A1122_20265	COG4174	ABC transporter (Permease)
A1122_20270	COG4166	transmembrane transport
A1122_20275	COG2200	EAL domain
A1122_20280	COG0791	NLP P60 protein
A1122_20285	COG0671	phosphoesterase, PA-phosphatase related
A1122_20290	COG0523	cobalamin synthesis protein
A1122_20300	COG2186	Transcriptional regulator
A1122_20305	COG0246	Mannitol dehydrogenase
A1122_20310	COG1312	Catalyzes the dehydration of D-mannonate
A1122_20330	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_20355	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A1122_20365	COG1129	ABC transporter
A1122_20370	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_20375	COG0494	nUDIX hydrolase
A1122_20385	COG1105	Belongs to the carbohydrate kinase PfkB family
A1122_20390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A1122_20390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_20390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_20395	COG3710	Transcriptional regulator
A1122_20410	COG3121	Chaperone
A1122_20415	COG3188	usher protein
A1122_20425	COG2855	membrane
A1122_20430	COG0583	DNA-binding transcription factor activity
A1122_20435	COG0833	amino acid
A1122_20445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_20455	COG4771	TonB-dependent receptor
A1122_20460	COG0625	glutathione transferase activity
A1122_20485	COG2011	ABC-type metal ion transport system permease component
A1122_20490	COG1686	Belongs to the peptidase S11 family
A1122_20500	COG0814	amino acid
A1122_20505	COG1349	DNA-binding transcription factor activity
A1122_20510	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A1122_20515	COG0671	phosphoesterase, PA-phosphatase related
A1122_20525	COG2985	domain, Protein
A1122_20525	COG0569	domain protein
A1122_20530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A1122_20545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A1122_20550	COG3842	ATPase activity
A1122_20555	COG1176	ABC-type spermidine putrescine transport system, permease component I
A1122_20560	COG1177	transmembrane transport
A1122_20575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_20600	COG1953	Uracil, thiamine, allantoin
A1122_20605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A1122_20615	COG2226	methyltransferase
A1122_20625	COG0741	lytic transglycosylase activity
A1122_20625	COG1388	LysM domain
A1122_20640	COG0656	L-ascorbic acid biosynthetic process
A1122_20645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A1122_20655	COG2011	ABC-type metal ion transport system permease component
A1122_20660	COG1464	Belongs to the NlpA lipoprotein family
A1122_20670	COG1720	tRNA m6t6A37 methyltransferase activity
A1122_20680	COG3015	lipoprotein NlpE involved in copper resistance
A1122_20690	COG4681	YaeQ
A1122_20700	COG4568	rho-dependent transcription termination
A1122_20710	COG0037	tRNA processing
A1122_20715	COG0346	lactoylglutathione lyase activity
A1122_20725	COG0587	DNA-directed DNA polymerase activity
A1122_20735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A1122_20755	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A1122_20765	COG0750	zinc metalloprotease
A1122_20770	COG0575	Belongs to the CDS family
A1122_20775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A1122_20805	COG0024	Methionine aminopeptidase
A1122_20830	COG0564	pseudouridine synthase activity
A1122_20835	COG3098	single-species biofilm formation
A1122_20840	COG1943	Transposase
A1122_20855	COG1611	Belongs to the LOG family
A1122_20860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1122_20870	COG2363	Small membrane protein
A1122_20875	COG0583	DNA-binding transcription factor activity
A1122_20885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A1122_20890	COG2166	iron-sulfur cluster assembly
A1122_20895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A1122_20900	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A1122_20905	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1122_20915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A1122_20920	COG1074	ATP-dependent DNA helicase activity
A1122_20930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A1122_20965	COG4771	TonB-dependent receptor
A1122_20970	COG2195	Cleaves the N-terminal amino acid of tripeptides
A1122_20975	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A1122_21020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_21030	COG5001	Diguanylate cyclase
A1122_21030	COG3300	MHYT domain
A1122_21035	COG2801	Transposase and inactivated derivatives
A1122_21045	COG2211	Major facilitator Superfamily
A1122_21272	COG1475	DNA binding
A1122_21277	COG1475	DNA binding
A1122_21282	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A1122_21322	COG1943	Transposase
A1122_21352	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A1122_21412	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A1122_21422	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1122_21467	COG1475	DNA binding
A1122_21567	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1122_21577	COG3344	reverse transcriptase
A1122_21602	COG3328	transposase activity
A1122_21667	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A1122_21677	COG5301	cellulose 1,4-beta-cellobiosidase activity
A1122_21677	COG5301	cellulose 1,4-beta-cellobiosidase activity
A1122_21712	COG3941	tape measure
A1122_21787	COG4683	PFAM Phage derived protein Gp49-like (DUF891)