locus-tag	class	description
CH57_10	COG0402	S-adenosylhomocysteine deaminase activity
CH57_1009	COG2951	lytic endotransglycosylase activity
CH57_101	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH57_1016	COG0243	molybdopterin cofactor binding
CH57_1017	COG0437	4 iron, 4 sulfur cluster binding
CH57_1018	COG3302	dmso reductase anchor subunit
CH57_1019	COG3381	protein complex oligomerization
CH57_102	COG0739	heme binding
CH57_1025	COG3038	cytochrome b561
CH57_1026	COG0436	Aminotransferase
CH57_103	COG1560	Kdo2-lipid A biosynthetic process
CH57_1031	COG0667	Aldo Keto reductase
CH57_1034	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH57_104	COG0469	pyruvate kinase activity
CH57_1040	COG1943	Transposase
CH57_1045	COG3530	Putative quorum-sensing-regulated virulence factor
CH57_1048	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH57_1049	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH57_105	COG1737	Transcriptional regulator
CH57_1050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_1052	COG2190	(PTS) system
CH57_1053	COG1943	Transposase
CH57_1055	COG2205	protein histidine kinase activity
CH57_1056	COG0745	RESPONSE REGULATOR receiver
CH57_1057	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_106	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH57_1060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH57_1062	COG0006	proline dipeptidase activity
CH57_1064	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH57_1066	COG5002	protein histidine kinase activity
CH57_1066	COG3850	Histidine kinase
CH57_1067	COG0745	RESPONSE REGULATOR receiver
CH57_1070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH57_1071	COG4208	sulfate ABC transporter
CH57_1072	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH57_1073	COG4150	thiosulfate binding
CH57_1075	COG1737	Transcriptional regulator
CH57_1076	COG2731	YhcH YjgK YiaL family protein
CH57_1078	COG4886	Leucine-rich repeat (LRR) protein
CH57_108	COG0800	Aldolase
CH57_1080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH57_1081	COG2837	iron assimilation
CH57_1083	COG3111	PFAM Bacterial OB fold (BOF) protein
CH57_1092	COG3005	denitrification pathway
CH57_1093	COG3043	anaerobic respiration
CH57_1095	COG3062	negative regulation of establishment of protein localization
CH57_1096	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_1096	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_1097	COG2197	response regulator
CH57_1099	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_1101	COG1988	membrane-bound metal-dependent
CH57_1102	COG0641	radical SAM
CH57_1103	COG3119	arylsulfatase activity
CH57_1104	COG3842	ATPase activity
CH57_1105	COG1175	transmembrane transport
CH57_1106	COG1840	ABC-type Fe3 transport system, periplasmic component
CH57_1108	COG1393	Belongs to the ArsC family
CH57_111	COG0251	oxidation-reduction process
CH57_1110	COG1876	peptidase activity
CH57_1114	COG2321	neutral zinc metallopeptidase
CH57_1116	COG1943	Transposase
CH57_1117	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH57_1119	COG2716	regulation of RNA biosynthetic process
CH57_112	COG1199	ATP-dependent helicase activity
CH57_1120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH57_1123	COG0628	permease
CH57_1124	COG4783	chaperone-mediated protein folding
CH57_1125	COG1393	Belongs to the ArsC family
CH57_1127	COG1943	Transposase
CH57_1130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH57_1132	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH57_1133	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH57_1134	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH57_1135	COG4181	ATPase activity
CH57_1136	COG2755	lipolytic protein G-D-S-L family
CH57_1137	COG0300	oxidoreductase activity
CH57_1138	COG3118	belongs to the thioredoxin family
CH57_1139	COG0330	HflC and HflK could
CH57_114	COG3065	identical protein binding
CH57_1140	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH57_1141	COG0789	Transcriptional regulator
CH57_1142	COG2217	Heavy metal translocating P-type atpase
CH57_1143	COG3735	TraB family
CH57_1144	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH57_1147	COG0737	Belongs to the 5'-nucleotidase family
CH57_1148	COG0737	Belongs to the 5'-nucleotidase family
CH57_1149	COG0737	Belongs to the 5'-nucleotidase family
CH57_115	COG0318	PFAM AMP-dependent synthetase and ligase
CH57_1150	COG2223	nitrite transmembrane transporter activity
CH57_1151	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH57_1151	COG4651	solute:proton antiporter activity
CH57_1152	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_1153	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH57_1159	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH57_116	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH57_1160	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH57_117	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH57_1170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_1174	COG0543	2 iron, 2 sulfur cluster binding
CH57_1174	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_118	COG2894	cell division
CH57_1180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH57_1184	COG2832	Protein of unknown function (DUF454)
CH57_1186	COG1196	nuclear chromosome segregation
CH57_1186	COG3264	Mechanosensitive ion channel
CH57_1187	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH57_1188	COG1309	transcriptional regulator
CH57_1189	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_1190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_1192	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH57_1196	COG3695	enzyme binding
CH57_1197	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH57_1198	COG1946	Acyl-CoA thioesterase
CH57_1199	COG0004	ammonium transporteR
CH57_1200	COG0347	Belongs to the P(II) protein family
CH57_1201	COG1132	(ABC) transporter
CH57_1202	COG1132	(ABC) transporter
CH57_1203	COG1522	sequence-specific DNA binding
CH57_1206	COG4533	DNA binding
CH57_1208	COG0824	Thioesterase
CH57_1209	COG1555	photosystem II stabilization
CH57_121	COG2951	lytic endotransglycosylase activity
CH57_1210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH57_1211	COG0776	regulation of translation
CH57_1212	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH57_1217	COG0271	Belongs to the BolA IbaG family
CH57_1218	COG3056	Lipoprotein
CH57_1219	COG2223	nitrite transmembrane transporter activity
CH57_122	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH57_1221	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH57_1222	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH57_1223	COG1845	cytochrome c oxidase, subunit III
CH57_1224	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH57_1226	COG2814	Major facilitator Superfamily
CH57_1228	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH57_1229	COG0693	protein deglycase activity
CH57_1232	COG0142	geranyltranstransferase activity
CH57_1234	COG1943	Transposase
CH57_1235	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH57_1236	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH57_1239	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH57_1239	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH57_124	COG0582	viral genome integration into host DNA
CH57_1243	COG1943	Transposase
CH57_1244	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH57_1245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH57_1246	COG1862	Preprotein translocase
CH57_1248	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CH57_1249	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CH57_1250	COG0450	alkyl hydroperoxide reductase
CH57_1251	COG1943	Transposase
CH57_1255	COG0366	Alpha amylase catalytic
CH57_1257	COG1114	Component of the transport system for branched-chain amino acids
CH57_1259	COG5002	protein histidine kinase activity
CH57_1260	COG0745	RESPONSE REGULATOR receiver
CH57_1261	COG0420	3'-5' exonuclease activity
CH57_1262	COG0419	ATPase involved in DNA repair
CH57_1265	COG1940	carbohydrate kinase activity
CH57_1270	COG2226	methyltransferase
CH57_1281	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH57_1285	COG1477	protein flavinylation
CH57_1289	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH57_1290	COG1805	sodium ion transport
CH57_1291	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH57_1292	COG0121	glutamine amidotransferase
CH57_1293	COG3034	peptidoglycan biosynthetic process
CH57_1295	COG1960	acyl-CoA dehydrogenase activity
CH57_1297	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH57_13	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH57_1301	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH57_1304	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH57_1313	COG2814	Major facilitator Superfamily
CH57_1314	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH57_1316	COG1846	Transcriptional regulator
CH57_1317	COG1566	PFAM secretion protein HlyD family protein
CH57_1318	COG2814	Major facilitator Superfamily
CH57_1319	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH57_1320	COG3118	belongs to the thioredoxin family
CH57_1322	COG1042	CoA-binding domain protein
CH57_1322	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH57_1322	COG0045	succinate-CoA ligase (ADP-forming) activity
CH57_1323	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH57_1324	COG5544	Lipoprotein
CH57_1331	COG0542	response to heat
CH57_1333	COG0564	pseudouridine synthase activity
CH57_1334	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH57_1335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH57_1336	COG1943	Transposase
CH57_1337	COG1605	Chorismate mutase
CH57_1337	COG0077	Prephenate dehydratase
CH57_1341	COG1605	Chorismate mutase
CH57_1341	COG0077	Prephenate dehydratase
CH57_1342	COG0287	Prephenate dehydrogenase
CH57_1342	COG1605	Chorismate mutase
CH57_1343	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH57_1344	COG3279	Response regulator of the LytR AlgR family
CH57_1345	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_1346	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_1347	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_1348	COG3137	Salt-induced outer membrane protein
CH57_1349	COG1943	Transposase
CH57_1354	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH57_1355	COG4137	Cytochrome C assembly protein
CH57_1356	COG4536	flavin adenine dinucleotide binding
CH57_1361	COG4536	flavin adenine dinucleotide binding
CH57_1362	COG1943	Transposase
CH57_1364	COG2918	glutathione biosynthetic process
CH57_1365	COG1238	metal cluster binding
CH57_1366	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_1371	COG3328	transposase activity
CH57_1372	COG3328	transposase activity
CH57_1373	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH57_1374	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH57_1375	COG3328	transposase activity
CH57_1376	COG3328	transposase activity
CH57_1383	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH57_1384	COG3958	Transketolase
CH57_1385	COG3959	Transketolase, thiamine diphosphate binding domain
CH57_1386	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_1387	COG1129	ABC transporter
CH57_1391	COG3783	Cytochrome b(562)
CH57_1392	COG3038	cytochrome b561
CH57_1393	COG3381	protein complex oligomerization
CH57_1394	COG3302	dmso reductase anchor subunit
CH57_1395	COG0437	4 iron, 4 sulfur cluster binding
CH57_1396	COG0243	molybdopterin cofactor binding
CH57_1397	COG0235	Class ii aldolase
CH57_1398	COG1349	DNA-binding transcription factor activity
CH57_14	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH57_1400	COG1943	Transposase
CH57_1401	COG1129	ABC transporter
CH57_1402	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_1403	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_1404	COG3623	hexulose-6-phosphate isomerase
CH57_1405	COG1070	Carbohydrate kinase
CH57_1406	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH57_1406	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH57_1408	COG0024	Methionine aminopeptidase
CH57_1411	COG4771	TonB-dependent receptor
CH57_1413	COG1858	cytochrome C peroxidase
CH57_1414	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_1418	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH57_1421	COG2376	Dihydroxyacetone kinase
CH57_1422	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_1423	COG1063	alcohol dehydrogenase
CH57_1424	COG0698	ribose 5-phosphate isomerase
CH57_1425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH57_1426	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH57_1427	COG4942	peptidase
CH57_1427	COG1388	LysM domain
CH57_1432	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CH57_1435	COG0529	Catalyzes the synthesis of activated sulfate
CH57_1446	COG0720	synthase
CH57_1447	COG0602	queuosine metabolic process
CH57_145	COG3328	transposase activity
CH57_1451	COG3956	TIGRFAM MazG family protein
CH57_1452	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH57_1453	COG2205	protein histidine kinase activity
CH57_1453	COG3850	Histidine kinase
CH57_1453	COG4999	Histidine kinase
CH57_1453	COG3437	response regulator, receiver
CH57_1454	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH57_1456	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH57_1458	COG2860	membrane
CH57_1462	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_1463	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH57_1464	COG1120	ATPase activity
CH57_1465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH57_1466	COG1643	Atp-dependent helicase
CH57_1467	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH57_1469	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH57_1470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH57_1471	COG0617	tRNA 3'-terminal CCA addition
CH57_1472	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH57_1476	COG0726	polysaccharide deacetylase
CH57_1477	COG0842	Transport permease protein
CH57_1478	COG1131	(ABC) transporter
CH57_1479	COG0288	reversible hydration of carbon dioxide
CH57_1480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH57_1481	COG2132	Multicopper oxidase
CH57_1485	COG0697	spore germination
CH57_1487	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH57_1488	COG1943	Transposase
CH57_1489	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH57_1490	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH57_1491	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH57_1492	COG2186	Transcriptional regulator
CH57_1493	COG1113	amino acid transport
CH57_1494	COG3725	Membrane protein required for beta-lactamase induction
CH57_1495	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH57_1497	COG4969	Belongs to the N-Me-Phe pilin family
CH57_1498	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH57_1499	COG1459	type II secretion system
CH57_15	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_1501	COG0237	dephospho-CoA kinase activity
CH57_1504	COG1943	Transposase
CH57_1509	COG0582	viral genome integration into host DNA
CH57_1511	COG0795	lipopolysaccharide-transporting ATPase activity
CH57_1512	COG0795	lipopolysaccharide-transporting ATPase activity
CH57_1514	COG2927	DNA polymerase III (CHI subunit)
CH57_1515	COG0525	valine-tRNA ligase activity
CH57_1517	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH57_1518	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CH57_1519	COG2731	YhcH YjgK YiaL family protein
CH57_1522	COG0601	transmembrane transport
CH57_1523	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_1524	COG0444	Belongs to the ABC transporter superfamily
CH57_1525	COG4608	Belongs to the ABC transporter superfamily
CH57_1529	COG2188	Transcriptional regulator
CH57_1530	COG3624	Phosphonate C-P lyase system protein PhnG
CH57_1531	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH57_1532	COG3626	phosphonate metabolism
CH57_1533	COG3627	carbon phosphorus lyase activity
CH57_1534	COG4107	phosphonate C-P lyase system protein PhnK
CH57_1535	COG4778	phosphonate C-P lyase system protein PhnL
CH57_1536	COG3454	Phosphonate metabolism
CH57_1537	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH57_1538	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH57_1539	COG0702	epimerase
CH57_1542	COG3842	ATPase activity
CH57_1543	COG0395	ABC-type sugar transport system, permease component
CH57_1545	COG1653	transport
CH57_1549	COG3153	acetyltransferase
CH57_1554	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_1557	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH57_1560	COG0513	Belongs to the DEAD box helicase family
CH57_1563	COG2801	Transposase and inactivated derivatives
CH57_1569	COG0195	Participates in both transcription termination and antitermination
CH57_1573	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH57_1575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH57_1576	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH57_1578	COG1534	Rna-binding protein
CH57_1579	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH57_1580	COG2027	D-alanyl-D-alanine carboxypeptidase
CH57_1581	COG0745	RESPONSE REGULATOR receiver
CH57_1582	COG0642	Histidine kinase
CH57_1584	COG0697	spore germination
CH57_1587	COG0142	geranyltranstransferase activity
CH57_1589	COG3423	Transcriptional regulator
CH57_1593	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH57_1595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH57_1596	COG2105	PFAM AIG2 family protein
CH57_1597	COG2911	Protein conserved in bacteria
CH57_1598	COG0729	surface antigen
CH57_1600	COG1253	flavin adenine dinucleotide binding
CH57_1602	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH57_1604	COG0737	Belongs to the 5'-nucleotidase family
CH57_1606	COG0545	Peptidyl-prolyl cis-trans isomerase
CH57_1607	COG3061	Opacity-associated protein A
CH57_1609	COG1943	Transposase
CH57_1611	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH57_1612	COG0360	Binds together with S18 to 16S ribosomal RNA
CH57_1614	COG1073	alpha beta
CH57_1617	COG0435	Glutathione S-transferase
CH57_1618	COG0583	DNA-binding transcription factor activity
CH57_1619	COG1741	Belongs to the pirin family
CH57_162	COG1943	Transposase
CH57_1620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH57_1624	COG2823	Periplasmic or secreted lipoprotein
CH57_1626	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH57_1627	COG2198	Histidine kinase
CH57_1627	COG0784	Response regulator, receiver
CH57_1627	COG5002	protein histidine kinase activity
CH57_1628	COG1242	4 iron, 4 sulfur cluster binding
CH57_1629	COG0069	glutamate synthase activity
CH57_1629	COG0067	glutamate synthase
CH57_1629	COG0070	glutamate synthase
CH57_1630	COG0493	'glutamate synthase
CH57_1632	COG2969	positive regulation of protein catabolic process
CH57_1633	COG0625	glutathione transferase activity
CH57_1636	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH57_1637	COG3105	Protein conserved in bacteria
CH57_1638	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH57_1639	COG1943	Transposase
CH57_1640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH57_1642	COG5007	Belongs to the BolA IbaG family
CH57_1643	COG3113	response to antibiotic
CH57_1644	COG2854	intermembrane phospholipid transfer
CH57_1645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH57_1646	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH57_1647	COG1127	ABC transporter
CH57_1648	COG0530	calcium, potassium:sodium antiporter activity
CH57_1649	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH57_1649	COG0517	IMP dehydrogenase activity
CH57_1650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH57_1651	COG3117	lipopolysaccharide transmembrane transporter activity
CH57_1652	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH57_1653	COG1137	ATPase activity
CH57_1654	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH57_1656	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_1658	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_1665	COG1609	Transcriptional regulator
CH57_1666	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_1666	COG1263	PTS System
CH57_1667	COG0366	Alpha amylase catalytic
CH57_1668	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH57_1669	COG3783	Cytochrome b(562)
CH57_1671	COG0312	modulator of DNA gyrase
CH57_1673	COG2732	(Barnase) inhibitor
CH57_1676	COG1012	belongs to the aldehyde dehydrogenase family
CH57_1680	COG0583	DNA-binding transcription factor activity
CH57_1691	COG0312	modulator of DNA gyrase
CH57_1692	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH57_1693	COG3164	Protein of unknown function
CH57_1694	COG1530	ribonuclease E activity
CH57_1696	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH57_1697	COG1792	Involved in formation and maintenance of cell shape
CH57_1698	COG1077	Cell shape determining protein MreB Mrl
CH57_1699	COG2199	diguanylate cyclase activity
CH57_1699	COG2200	EAL domain
CH57_1700	COG0604	alcohol dehydrogenase
CH57_1701	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH57_1704	COG0511	ligase activity, forming carbon-carbon bonds
CH57_1705	COG0439	Biotin carboxylase
CH57_1707	COG3924	membrane
CH57_1708	COG4145	pantothenate transmembrane transporter activity
CH57_1710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH57_1711	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH57_1715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH57_1717	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH57_1718	COG3133	Outer membrane lipoprotein
CH57_1719	COG1278	Cold shock
CH57_1720	COG1278	Cold shock
CH57_1721	COG1943	Transposase
CH57_1724	COG0625	glutathione transferase activity
CH57_1726	COG1069	ribulokinase activity
CH57_1728	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_1729	COG1129	ABC transporter
CH57_1731	COG1560	Kdo2-lipid A biosynthetic process
CH57_1733	COG0025	NhaP-type Na H and K H
CH57_1734	COG2252	PERMEase
CH57_1735	COG3077	Addiction module antitoxin, RelB DinJ family
CH57_1737	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH57_1739	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH57_1740	COG0431	NADPH-dependent FMN reductase
CH57_1742	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_1743	COG1869	D-ribose catabolic process
CH57_1744	COG1917	Cupin 2, conserved barrel domain protein
CH57_1744	COG2207	Transcriptional regulator
CH57_1745	COG0673	inositol 2-dehydrogenase activity
CH57_1748	COG3209	COG3209 Rhs family protein
CH57_1750	COG3501	Rhs element vgr protein
CH57_1756	COG3209	COG3209 Rhs family protein
CH57_1759	COG3501	Rhs element vgr protein
CH57_1775	COG2801	Transposase and inactivated derivatives
CH57_178	COG3328	transposase activity
CH57_1787	COG1175	transmembrane transport
CH57_1788	COG3833	ABC-type maltose transport systems, permease component
CH57_1791	COG0527	aspartate kinase activity
CH57_1795	COG1414	Transcriptional regulator
CH57_1796	COG1414	Transcriptional regulator
CH57_1798	COG2224	Isocitrate lyase
CH57_1799	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH57_180	COG1104	cysteine desulfurase activity
CH57_1809	COG0151	Belongs to the GarS family
CH57_1812	COG3068	Protein conserved in bacteria
CH57_1813	COG1515	deoxyribonuclease V activity
CH57_1818	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH57_1820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH57_1822	COG2022	thiamine diphosphate biosynthetic process
CH57_1824	COG1943	Transposase
CH57_1831	COG0250	Participates in transcription elongation, termination and antitermination
CH57_1832	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH57_1843	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH57_1849	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH57_1850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH57_1851	COG1739	Uncharacterized protein family UPF0029
CH57_1852	COG1943	Transposase
CH57_1853	COG1739	Uncharacterized protein family UPF0029
CH57_186	COG2719	SpoVR family
CH57_1866	COG0805	protein transport
CH57_1868	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH57_1872	COG1322	Protein conserved in bacteria
CH57_1873	COG0586	Pfam SNARE associated Golgi protein
CH57_1874	COG1966	Carbon starvation protein
CH57_1876	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CH57_1877	COG0412	Dienelactone hydrolase
CH57_188	COG2814	Major facilitator Superfamily
CH57_1880	COG0583	DNA-binding transcription factor activity
CH57_1881	COG0679	Auxin Efflux Carrier
CH57_1882	COG0584	glycerophosphoryl diester phosphodiesterase
CH57_1894	COG0410	ABC transporter
CH57_1895	COG0411	ABC transporter
CH57_1896	COG4177	L-phenylalanine transmembrane transporter activity
CH57_1897	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH57_1898	COG0683	leucine binding
CH57_190	COG0583	DNA-binding transcription factor activity
CH57_1900	COG1943	Transposase
CH57_1902	COG2177	Part of the ABC transporter FtsEX involved in
CH57_1903	COG2884	Cell division ATP-binding protein ftsE
CH57_1904	COG0552	protein localization to endoplasmic reticulum
CH57_1904	COG0552	protein localization to endoplasmic reticulum
CH57_1905	COG0742	ribosomal rna small subunit methyltransferase
CH57_1906	COG3776	membrane
CH57_1909	COG3714	YhhN family
CH57_1912	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH57_1914	COG0247	lactate metabolic process
CH57_1916	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH57_1917	COG0584	glycerophosphoryl diester phosphodiesterase
CH57_1919	COG0561	phosphatase activity
CH57_1920	COG2267	carboxylic ester hydrolase activity
CH57_1921	COG1280	lysine exporter protein (LysE YggA)
CH57_1922	COG1280	lysine exporter protein (LysE YggA)
CH57_1923	COG0514	ATP-dependent DNA helicase (RecQ)
CH57_1924	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH57_1925	COG2050	protein possibly involved in aromatic compounds catabolism
CH57_1927	COG0598	Magnesium transport protein CorA
CH57_1928	COG5564	TIM-barrel signal transduction protein
CH57_1929	COG5441	Belongs to the UPF0261 family
CH57_193	COG2766	serine protein kinase
CH57_1931	COG0210	DNA helicase
CH57_1932	COG1011	Hydrolase
CH57_1933	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH57_1934	COG3159	Protein conserved in bacteria
CH57_1936	COG5567	small periplasmic lipoprotein
CH57_1938	COG3072	Adenylate cyclase
CH57_194	COG3713	MltA-interacting MipA family protein
CH57_1940	COG1587	Uroporphyrinogen-III synthase
CH57_1941	COG2959	enzyme of heme biosynthesis
CH57_1942	COG3071	HemY protein
CH57_1943	COG1943	Transposase
CH57_1953	COG1113	amino acid transport
CH57_1957	COG2244	polysaccharide biosynthetic process
CH57_1958	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH57_1959	COG0456	acetyltransferase
CH57_1960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH57_1961	COG1088	dTDP-glucose 4,6-dehydratase activity
CH57_1962	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH57_1963	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH57_1964	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH57_1965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH57_1966	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH57_1967	COG3118	belongs to the thioredoxin family
CH57_1972	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH57_1974	COG3328	transposase activity
CH57_1976	COG3121	Chaperone
CH57_1979	COG3121	Chaperone
CH57_198	COG3139	Protein of unknown function (DUF1315)
CH57_1985	COG0583	DNA-binding transcription factor activity
CH57_199	COG1335	isochorismatase
CH57_1994	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH57_1995	COG3978	acetolactate synthase activity
CH57_1998	COG3085	chromosome segregation
CH57_1999	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_200	COG0252	asparaginase activity
CH57_2001	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_2002	COG1129	ABC transporter
CH57_2003	COG1879	ABC-type sugar transport system periplasmic component
CH57_201	COG0616	signal peptide processing
CH57_2017	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH57_2017	COG0678	peroxiredoxin activity
CH57_2018	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH57_202	COG0778	Nitroreductase
CH57_2023	COG1629	transport
CH57_2027	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH57_203	COG0709	Synthesizes selenophosphate from selenide and ATP
CH57_2034	COG2801	Transposase and inactivated derivatives
CH57_2037	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH57_2038	COG0058	SHG alpha-glucan phosphorylase activity
CH57_204	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH57_2040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CH57_2043	COG3275	phosphorelay sensor kinase activity
CH57_2049	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH57_2050	COG2095	MarC family integral membrane protein
CH57_2054	COG3265	gluconokinase activity
CH57_2055	COG2610	gluconate transmembrane transporter activity
CH57_2056	COG1609	Transcriptional regulator
CH57_2057	COG1741	Belongs to the pirin family
CH57_2059	COG0745	RESPONSE REGULATOR receiver
CH57_206	COG0494	nUDIX hydrolase
CH57_2061	COG0191	fructose-bisphosphate aldolase activity
CH57_2063	COG1879	ABC-type sugar transport system periplasmic component
CH57_2064	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_2067	COG2081	HI0933 family
CH57_2068	COG0306	phosphate transporter
CH57_2069	COG1943	Transposase
CH57_207	COG0708	Exodeoxyribonuclease III
CH57_2071	COG0589	response to stress
CH57_2075	COG0339	signal peptide processing
CH57_2076	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH57_2077	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH57_2078	COG3835	regulator
CH57_2079	COG2610	gluconate transmembrane transporter activity
CH57_208	COG0583	DNA-binding transcription factor activity
CH57_2080	COG1929	Belongs to the glycerate kinase type-1 family
CH57_2085	COG1295	ribonuclease BN
CH57_2086	COG2982	Protein involved in outer membrane biogenesis
CH57_2087	COG2134	cdp-diacylglycerol pyrophosphatase
CH57_2088	COG2200	EAL domain
CH57_2089	COG1942	4-Oxalocrotonate Tautomerase
CH57_2090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_2091	COG0612	Peptidase, M16
CH57_2096	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH57_2097	COG2200	EAL domain
CH57_2097	COG2199	diguanylate cyclase activity
CH57_2098	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH57_2099	COG4608	Belongs to the ABC transporter superfamily
CH57_2100	COG0444	Belongs to the ABC transporter superfamily
CH57_2101	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_2102	COG0601	transmembrane transport
CH57_2103	COG0747	negative chemotaxis
CH57_2105	COG2831	hemolysin activation secretion protein
CH57_2109	COG2271	Major facilitator Superfamily
CH57_211	COG0788	formyltetrahydrofolate deformylase activity
CH57_2110	COG3851	Histidine kinase
CH57_2111	COG2197	response regulator
CH57_2112	COG2194	sulfuric ester hydrolase activity
CH57_2115	COG2986	histidine ammonia-lyase
CH57_2119	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH57_212	COG3328	transposase activity
CH57_2122	COG4607	ABC-type enterochelin transport system periplasmic component
CH57_2124	COG4605	iron ion homeostasis
CH57_2126	COG4604	ABC transporter, ATP-binding protein
CH57_2133	COG0582	viral genome integration into host DNA
CH57_2135	COG2207	Transcriptional regulator
CH57_2135	COG1609	Transcriptional regulator
CH57_2136	COG4214	carbohydrate transport
CH57_2138	COG4213	ABC transporter substrate-binding protein
CH57_214	COG0745	RESPONSE REGULATOR receiver
CH57_2140	COG1070	Carbohydrate kinase
CH57_2142	COG3121	Chaperone
CH57_2143	COG3188	usher protein
CH57_2144	COG3188	usher protein
CH57_2146	COG3274	enterobacterial common antigen metabolic process
CH57_2148	COG2801	Transposase and inactivated derivatives
CH57_2159	COG2864	formate dehydrogenase
CH57_216	COG2916	Histone family protein nucleoid-structuring protein H-NS
CH57_2160	COG0437	4 iron, 4 sulfur cluster binding
CH57_2161	COG3383	formate dehydrogenase (NAD+) activity
CH57_2161	COG0243	molybdopterin cofactor binding
CH57_2162	COG0243	molybdopterin cofactor binding
CH57_2162	COG3383	formate dehydrogenase (NAD+) activity
CH57_2164	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH57_217	COG1435	thymidine kinase activity
CH57_2171	COG3722	fumarate hydratase activity
CH57_2173	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_2173	COG2213	PTS system mannitol-specific
CH57_2178	COG2818	Glycosylase
CH57_2180	COG2885	chlorophyll binding
CH57_2183	COG0366	Alpha amylase catalytic
CH57_2185	COG3977	Valine--pyruvate aminotransferase
CH57_2189	COG5645	(Lipo)protein
CH57_2190	COG0823	Involved in the tonB-independent uptake of proteins
CH57_2191	COG0823	Involved in the tonB-independent uptake of proteins
CH57_2192	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH57_2193	COG2423	ornithine cyclodeaminase activity
CH57_2196	COG2801	Transposase and inactivated derivatives
CH57_2197	COG0561	phosphatase activity
CH57_2198	COG0187	DNA topoisomerase II activity
CH57_2199	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH57_220	COG1454	alcohol dehydrogenase
CH57_220	COG1012	belongs to the aldehyde dehydrogenase family
CH57_2200	COG0592	DNA-directed DNA polymerase activity
CH57_2203	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH57_2206	COG0706	membrane insertase activity
CH57_221	COG2095	MarC family integral membrane protein
CH57_2211	COG2252	PERMEase
CH57_2212	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_2213	COG0765	amino acid transport
CH57_2214	COG0765	amino acid transport
CH57_2215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_2217	COG0704	Plays a role in the regulation of phosphate uptake
CH57_2219	COG0581	inorganic phosphate transmembrane transporter activity
CH57_2220	COG0573	inorganic phosphate transmembrane transporter activity
CH57_2221	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH57_2222	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH57_223	COG0601	transmembrane transport
CH57_2232	COG3312	ion transport
CH57_2235	COG0716	FMN binding
CH57_2236	COG1522	sequence-specific DNA binding
CH57_224	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_2243	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_2244	COG0477	Major facilitator Superfamily
CH57_2246	COG2186	Transcriptional regulator
CH57_225	COG0444	Belongs to the ABC transporter superfamily
CH57_2251	COG3328	transposase activity
CH57_2252	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH57_2254	COG3084	Protein conserved in bacteria
CH57_2255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH57_2256	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH57_2257	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH57_2257	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH57_2258	COG1943	Transposase
CH57_226	COG4608	Belongs to the ABC transporter superfamily
CH57_2261	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH57_2263	COG3852	Histidine kinase
CH57_2264	COG0174	glutamine synthetase
CH57_2266	COG1011	Hydrolase
CH57_2267	COG1295	ribonuclease BN
CH57_2271	COG0456	acetyltransferase
CH57_2272	COG2982	Protein involved in outer membrane biogenesis
CH57_2273	COG2233	PERMEase
CH57_2274	COG0786	glutamate:sodium symporter activity
CH57_2275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH57_2276	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH57_2277	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH57_2280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH57_2281	COG2860	membrane
CH57_2282	COG1561	YicC-like family, N-terminal region
CH57_2287	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH57_2290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH57_2294	COG1519	Transferase
CH57_2295	COG0859	PFAM glycosyl transferase family 9
CH57_2296	COG0859	PFAM glycosyl transferase family 9
CH57_2298	COG0156	8-amino-7-oxononanoate synthase activity
CH57_2300	COG2861	carbohydrate metabolic process
CH57_2301	COG2861	carbohydrate metabolic process
CH57_2302	COG4942	peptidase
CH57_2304	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH57_2305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH57_2308	COG1045	serine acetyltransferase
CH57_2309	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH57_2310	COG2169	Transcriptional regulator
CH57_2310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH57_2311	COG2205	protein histidine kinase activity
CH57_2312	COG0745	RESPONSE REGULATOR receiver
CH57_2313	COG3678	ATP-independent chaperone mediated protein folding
CH57_2318	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH57_2320	COG0471	metal ion transport
CH57_2321	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH57_2322	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH57_2323	COG0583	DNA-binding transcription factor activity
CH57_2326	COG3152	Membrane
CH57_2328	COG1494	fructose-1,6-bisphosphatase
CH57_2329	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH57_233	COG2350	Protein conserved in bacteria
CH57_2330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH57_2332	COG1943	Transposase
CH57_2342	COG1575	Belongs to the MenA family. Type 1 subfamily
CH57_2345	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH57_2346	COG1609	Transcriptional regulator
CH57_2348	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH57_235	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH57_2350	COG4682	membrane
CH57_2352	COG0626	cystathionine gamma-synthase activity
CH57_2353	COG0626	cystathionine gamma-synthase activity
CH57_2354	COG0527	aspartate kinase activity
CH57_2354	COG0460	homoserine dehydrogenase
CH57_2356	COG2801	Transposase and inactivated derivatives
CH57_2358	COG1349	DNA-binding transcription factor activity
CH57_236	COG3328	transposase activity
CH57_2360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH57_2362	COG0058	SHG alpha-glucan phosphorylase activity
CH57_2363	COG0058	SHG alpha-glucan phosphorylase activity
CH57_2364	COG1640	4-alpha-glucanotransferase
CH57_237	COG3328	transposase activity
CH57_2371	COG1918	ferrous iron import across plasma membrane
CH57_2372	COG2183	response to ionizing radiation
CH57_2373	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH57_2374	COG0745	RESPONSE REGULATOR receiver
CH57_2378	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH57_2379	COG1011	Hydrolase
CH57_238	COG1607	acyl-coa hydrolase
CH57_2382	COG0494	nUDIX hydrolase
CH57_2383	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH57_2388	COG4796	Type ii and iii secretion system protein
CH57_2393	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH57_2394	COG0546	phosphoglycolate phosphatase activity
CH57_2395	COG0180	Tryptophanyl-tRNA synthetase
CH57_2398	COG2146	nitrite reductase [NAD(P)H] activity
CH57_2399	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH57_24	COG3328	transposase activity
CH57_2400	COG0402	S-adenosylhomocysteine deaminase activity
CH57_2405	COG1486	melibiose metabolic process
CH57_2406	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH57_2407	COG0433	COG0433 Predicted ATPase
CH57_2410	COG1289	transmembrane transporter activity
CH57_2412	COG1765	OsmC-like protein
CH57_2414	COG3954	Phosphoribulokinase
CH57_2416	COG0429	hydrolase of the alpha beta-hydrolase fold
CH57_2418	COG4521	taurine ABC transporter
CH57_2420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH57_2421	COG2175	clavaminate synthase activity
CH57_2423	COG1216	Glycosyl transferase, family 2
CH57_2424	COG0488	(ABC) transporter
CH57_2425	COG0488	(ABC) transporter
CH57_2428	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH57_2429	COG1047	Peptidyl-prolyl cis-trans
CH57_243	COG3047	cAMP biosynthetic process
CH57_2431	COG0545	Peptidyl-prolyl cis-trans isomerase
CH57_2432	COG2964	Protein conserved in bacteria
CH57_2436	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH57_2437	COG0049	tRNA binding
CH57_2440	COG1943	Transposase
CH57_2443	COG0051	transcription antitermination factor activity, RNA binding
CH57_2448	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH57_2450	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH57_2451	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH57_2453	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH57_2454	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH57_2462	COG1841	ribosomal large subunit assembly
CH57_2464	COG0201	protein transport
CH57_2465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH57_2468	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH57_247	COG0135	phosphoribosylanthranilate isomerase activity
CH57_247	COG0134	indole-3-glycerol-phosphate synthase activity
CH57_2471	COG0789	Transcriptional regulator
CH57_2472	COG3036	rescue of stalled ribosome
CH57_2474	COG0569	domain protein
CH57_2478	COG0758	DNA mediated transformation
CH57_2480	COG0551	DNA topoisomerase type I activity
CH57_2483	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH57_2488	COG3162	membrane
CH57_249	COG0512	Glutamine amidotransferase of anthranilate synthase
CH57_2490	COG1301	dicarboxylic acid transport
CH57_2512	COG2391	methyltransferase activity
CH57_2513	COG0425	Belongs to the sulfur carrier protein TusA family
CH57_2514	COG0583	DNA-binding transcription factor activity
CH57_2515	COG0814	amino acid
CH57_2516	COG0626	cystathionine gamma-synthase activity
CH57_2518	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_2519	COG4558	Periplasmic binding protein
CH57_252	COG0009	L-threonylcarbamoyladenylate synthase
CH57_2520	COG3720	iron ion transport
CH57_2521	COG4771	TonB-dependent receptor
CH57_2522	COG0702	epimerase
CH57_2523	COG3721	Heme iron utilization protein
CH57_2528	COG1358	cellular component organization or biogenesis
CH57_253	COG1187	pseudouridine synthase activity
CH57_2540	COG3121	Chaperone
CH57_2548	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH57_255	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_2550	COG0735	belongs to the Fur family
CH57_2551	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH57_2554	COG0305	Participates in initiation and elongation during chromosome replication
CH57_2555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH57_2556	COG1448	Aminotransferase
CH57_2557	COG2315	Protein conserved in bacteria
CH57_2558	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH57_2559	COG0629	single-stranded DNA binding
CH57_256	COG0616	signal peptide processing
CH57_2561	COG1454	alcohol dehydrogenase
CH57_2574	COG1309	transcriptional regulator
CH57_2575	COG0493	'glutamate synthase
CH57_2575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_2576	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_2577	COG3383	formate dehydrogenase (NAD+) activity
CH57_2580	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_2588	COG2076	Multidrug Resistance protein
CH57_2589	COG1943	Transposase
CH57_259	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH57_2590	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH57_2592	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH57_2593	COG1053	succinate dehydrogenase
CH57_2595	COG1511	domain protein
CH57_2595	COG3264	Mechanosensitive ion channel
CH57_2598	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH57_260	COG0583	DNA-binding transcription factor activity
CH57_2601	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH57_2602	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH57_2602	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH57_2603	COG0802	atpase or kinase
CH57_2604	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH57_2608	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH57_2609	COG0330	HflC and HflK could
CH57_2610	COG0330	HflC and HflK could
CH57_2611	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH57_2614	COG0557	exoribonuclease II activity
CH57_2615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH57_2616	COG1960	acyl-CoA dehydrogenase activity
CH57_2617	COG3650	response to hydrogen peroxide
CH57_262	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH57_2622	COG1401	restriction endodeoxyribonuclease activity
CH57_2624	COG2963	transposase activity
CH57_263	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH57_2634	COG4269	membrane
CH57_2636	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_2637	COG2207	Transcriptional regulator
CH57_2638	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_2639	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_264	COG0671	phosphoesterase, PA-phosphatase related
CH57_2640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_2640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_2640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH57_2648	COG2390	Transcriptional regulator
CH57_2649	COG2390	Transcriptional regulator
CH57_265	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH57_2651	COG0859	PFAM glycosyl transferase family 9
CH57_2654	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_2655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_2658	COG3706	GGDEF domain
CH57_266	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH57_2662	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH57_2663	COG0456	acetyltransferase
CH57_2665	COG2823	Periplasmic or secreted lipoprotein
CH57_2667	COG4667	esterase of the alpha-beta hydrolase superfamily
CH57_2668	COG0084	hydrolase, TatD family'
CH57_2669	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH57_2670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH57_2677	COG3726	membrane protein affecting hemolysin expression
CH57_2678	COG0560	Phosphoserine phosphatase
CH57_2682	COG0488	(ABC) transporter
CH57_2683	COG0488	(ABC) transporter
CH57_2684	COG2885	chlorophyll binding
CH57_2685	COG2199	diguanylate cyclase activity
CH57_2688	COG0741	lytic transglycosylase activity
CH57_269	COG0023	Translation Initiation Factor
CH57_2690	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH57_2691	COG2207	Transcriptional regulator
CH57_2691	COG3708	Transcriptional regulator
CH57_2694	COG3045	CreA protein
CH57_2695	COG0745	RESPONSE REGULATOR receiver
CH57_2703	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH57_2706	COG1584	GPR1 FUN34 yaaH family protein
CH57_2710	COG0583	DNA-binding transcription factor activity
CH57_2712	COG0196	riboflavin kinase activity
CH57_2715	COG1047	Peptidyl-prolyl cis-trans
CH57_2717	COG1943	Transposase
CH57_2719	COG0505	Belongs to the CarA family
CH57_2720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH57_2721	COG1280	lysine exporter protein (LysE YggA)
CH57_2722	COG2966	Psort location CytoplasmicMembrane, score
CH57_2724	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH57_2725	COG1943	Transposase
CH57_273	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH57_2730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH57_2731	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH57_2733	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH57_2734	COG0564	pseudouridine synthase activity
CH57_274	COG2879	small protein
CH57_2744	COG3501	Rhs element vgr protein
CH57_275	COG1966	Carbon starvation protein
CH57_2752	COG3047	cAMP biosynthetic process
CH57_2752	COG2885	chlorophyll binding
CH57_2756	COG0417	DNA replication proofreading
CH57_2757	COG0586	Pfam SNARE associated Golgi protein
CH57_2759	COG1178	ABC-type Fe3 transport system permease component
CH57_2760	COG4143	(ABC) transporter
CH57_2763	COG2814	Major facilitator Superfamily
CH57_2767	COG2814	Major facilitator Superfamily
CH57_277	COG2271	Major facilitator Superfamily
CH57_2770	COG0473	3-isopropylmalate dehydrogenase activity
CH57_2772	COG1943	Transposase
CH57_2775	COG1022	Amp-dependent synthetase and ligase
CH57_2776	COG0028	Belongs to the TPP enzyme family
CH57_2778	COG1943	Transposase
CH57_2779	COG1609	Transcriptional regulator
CH57_278	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_2783	COG3116	cell division
CH57_2784	COG0768	penicillin binding
CH57_2785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH57_2786	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH57_2789	COG0772	Belongs to the SEDS family
CH57_279	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH57_2793	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH57_2794	COG0849	cell division
CH57_2795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH57_2800	COG0494	nUDIX hydrolase
CH57_2803	COG0435	Glutathione S-transferase
CH57_2804	COG2259	Doxx family
CH57_2806	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH57_2807	COG4575	ribosome binding
CH57_281	COG4659	FMN binding
CH57_2810	COG0586	Pfam SNARE associated Golgi protein
CH57_2813	COG2271	Major facilitator Superfamily
CH57_2815	COG0246	Mannitol dehydrogenase
CH57_2816	COG2721	sulfolactate sulfo-lyase activity
CH57_2818	COG1943	Transposase
CH57_282	COG4658	electron transport chain
CH57_2821	COG0673	inositol 2-dehydrogenase activity
CH57_2822	COG1451	nucleotide metabolic process
CH57_2825	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH57_2825	COG1902	pentaerythritol trinitrate reductase activity
CH57_2826	COG3247	response to pH
CH57_2829	COG4245	von Willebrand factor, type A
CH57_283	COG2207	Transcriptional regulator
CH57_283	COG3708	Transcriptional regulator
CH57_2832	COG4245	von Willebrand factor, type A
CH57_2833	COG2831	hemolysin activation secretion protein
CH57_2834	COG3210	domain, Protein
CH57_2836	COG3210	domain, Protein
CH57_2838	COG3210	domain, Protein
CH57_2842	COG3842	ATPase activity
CH57_2843	COG3459	Glycosyltransferase 36 associated
CH57_2844	COG1609	Transcriptional regulator
CH57_2845	COG1653	transport
CH57_2847	COG0395	ABC-type sugar transport system, permease component
CH57_2851	COG1289	transmembrane transporter activity
CH57_2859	COG0251	oxidation-reduction process
CH57_2876	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH57_2877	COG0358	DNA primase activity
CH57_2881	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH57_2884	COG4991	sh3 domain protein
CH57_2885	COG3025	triphosphatase activity
CH57_2888	COG0531	amino acid
CH57_2892	COG3384	dioxygenase
CH57_2893	COG0754	glutathionylspermidine amidase activity
CH57_2896	COG1538	Outer membrane efflux protein
CH57_2897	COG0494	nUDIX hydrolase
CH57_2898	COG3151	Protein conserved in bacteria
CH57_2899	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH57_29	COG0500	methyltransferase
CH57_290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_2900	COG3150	esterase
CH57_2901	COG0187	DNA topoisomerase II activity
CH57_2902	COG0583	DNA-binding transcription factor activity
CH57_2903	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH57_2904	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH57_2905	COG0204	Acyl-transferase
CH57_2906	COG2132	Multicopper oxidase
CH57_2909	COG0656	L-ascorbic acid biosynthetic process
CH57_291	COG2274	protein secretion by the type I secretion system
CH57_2910	COG1979	alcohol dehydrogenase
CH57_2911	COG2207	Transcriptional regulator
CH57_2912	COG0586	Pfam SNARE associated Golgi protein
CH57_2913	COG0626	cystathionine gamma-synthase activity
CH57_2914	COG0811	peptide transport
CH57_2916	COG0848	biopolymer transport protein
CH57_2926	COG4964	Belongs to the GSP D family
CH57_2927	COG4964	Belongs to the GSP D family
CH57_2931	COG1943	Transposase
CH57_2935	COG4592	Periplasmic binding protein
CH57_2940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH57_2941	COG1684	flagellar biosynthetic protein fliR
CH57_2942	COG1987	bacterial-type flagellum assembly
CH57_2946	COG2204	response regulator
CH57_295	COG1879	ABC-type sugar transport system periplasmic component
CH57_2955	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH57_2956	COG1815	bacterial-type flagellum-dependent cell motility
CH57_2957	COG1558	bacterial-type flagellum-dependent cell motility
CH57_2958	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH57_2959	COG1749	Flagellar hook protein flgE
CH57_2961	COG1943	Transposase
CH57_2963	COG4786	Flagellar basal body rod
CH57_2964	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH57_2965	COG1706	bacterial-type flagellum-dependent cell motility
CH57_2967	COG1256	bacterial-type flagellum assembly
CH57_297	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_2971	COG3710	Transcriptional regulator
CH57_2975	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH57_2980	COG1191	sigma factor activity
CH57_2981	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH57_2986	COG3133	Outer membrane lipoprotein
CH57_2987	COG3133	Outer membrane lipoprotein
CH57_299	COG0673	inositol 2-dehydrogenase activity
CH57_2990	COG2801	Transposase and inactivated derivatives
CH57_2992	COG0471	metal ion transport
CH57_2995	COG3209	COG3209 Rhs family protein
CH57_2997	COG3501	Rhs element vgr protein
CH57_300	COG0385	Bile acid
CH57_3000	COG2610	gluconate transmembrane transporter activity
CH57_3004	COG1132	(ABC) transporter
CH57_3010	COG3433	isochorismatase activity
CH57_3010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH57_3010	COG2226	methyltransferase
CH57_3011	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH57_3012	COG3433	isochorismatase activity
CH57_3012	COG2226	methyltransferase
CH57_3012	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH57_302	COG5339	Protein conserved in bacteria
CH57_3022	COG0667	Aldo Keto reductase
CH57_3028	COG0019	diaminopimelate decarboxylase activity
CH57_3029	COG1609	Transcriptional regulator
CH57_3030	COG2814	Major facilitator Superfamily
CH57_3031	COG0583	DNA-binding transcription factor activity
CH57_3032	COG0583	DNA-binding transcription factor activity
CH57_3034	COG0840	transmembrane signaling receptor activity
CH57_304	COG0114	fumarate hydratase activity
CH57_3053	COG0288	reversible hydration of carbon dioxide
CH57_306	COG2814	Major facilitator Superfamily
CH57_3062	COG1943	Transposase
CH57_3063	COG3119	arylsulfatase activity
CH57_3064	COG1349	DNA-binding transcription factor activity
CH57_3066	COG2222	sugar isomerase
CH57_3067	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_3068	COG3715	PTS system
CH57_3069	COG3716	PTS system mannose fructose sorbose family IID component
CH57_307	COG0583	DNA-binding transcription factor activity
CH57_3070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_3072	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3074	COG0641	radical SAM
CH57_3075	COG3119	arylsulfatase activity
CH57_3077	COG0191	fructose-bisphosphate aldolase activity
CH57_308	COG1940	carbohydrate kinase activity
CH57_3081	COG2271	Major facilitator Superfamily
CH57_3085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_3085	COG1263	PTS System
CH57_3086	COG1874	Beta-galactosidase
CH57_3087	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH57_3088	COG3833	ABC-type maltose transport systems, permease component
CH57_3089	COG1175	transmembrane transport
CH57_3090	COG2182	Extracellular solute-binding protein
CH57_3092	COG1129	ABC transporter
CH57_3093	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_3094	COG1879	ABC-type sugar transport system periplasmic component
CH57_3096	COG0791	NLP P60 protein
CH57_3097	COG1695	Transcriptional regulator
CH57_310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH57_311	COG0038	chloride channel
CH57_3114	COG2944	sequence-specific DNA binding
CH57_3119	COG0582	viral genome integration into host DNA
CH57_3123	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH57_3124	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH57_3125	COG4974	Belongs to the 'phage' integrase family
CH57_3126	COG0716	FMN binding
CH57_3127	COG4452	Inner membrane protein CreD
CH57_3128	COG2205	protein histidine kinase activity
CH57_3129	COG0745	RESPONSE REGULATOR receiver
CH57_3130	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH57_3133	COG1272	protein, Hemolysin III
CH57_3135	COG5295	Hep Hag repeat protein
CH57_3141	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH57_3142	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH57_3143	COG0006	proline dipeptidase activity
CH57_3146	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH57_3147	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH57_3148	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH57_3153	COG0191	fructose-bisphosphate aldolase activity
CH57_3158	COG1943	Transposase
CH57_3159	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH57_3160	COG0501	Belongs to the peptidase M48B family
CH57_3162	COG1166	arginine decarboxylase activity
CH57_3165	COG3091	SprT-like family
CH57_3166	COG2356	endonuclease I
CH57_3167	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH57_3168	COG0189	ligase activity
CH57_3171	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH57_3173	COG2805	Type II/IV secretion system protein
CH57_3174	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH57_3175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH57_3176	COG0762	integral membrane protein
CH57_3178	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH57_3179	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH57_3180	COG1073	alpha beta
CH57_3180	COG3064	Membrane
CH57_3180	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH57_3183	COG2066	Belongs to the glutaminase family
CH57_3184	COG3171	Protein conserved in bacteria
CH57_3186	COG1194	a g-specific adenine glycosylase
CH57_3190	COG4774	siderophore transport
CH57_3191	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_3192	COG1129	ABC transporter
CH57_3193	COG1879	ABC-type sugar transport system periplasmic component
CH57_3194	COG1982	Orn Lys Arg decarboxylase major
CH57_3198	COG1662	PFAM IS1 transposase
CH57_321	COG4128	Pfam Zonular occludens toxin
CH57_3219	COG2771	luxR family
CH57_3220	COG3916	Acyl-homoserine-lactone synthase
CH57_3230	COG2211	Major facilitator Superfamily
CH57_3232	COG2801	Transposase and inactivated derivatives
CH57_3233	COG3300	MHYT domain
CH57_3233	COG5001	Diguanylate cyclase
CH57_3235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_3243	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH57_3244	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH57_3245	COG4771	TonB-dependent receptor
CH57_3252	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH57_3254	COG1074	ATP-dependent DNA helicase activity
CH57_3255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH57_3257	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH57_3260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH57_3261	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH57_3262	COG2166	iron-sulfur cluster assembly
CH57_3263	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH57_3265	COG0583	DNA-binding transcription factor activity
CH57_3266	COG2363	Small membrane protein
CH57_3268	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH57_3269	COG1611	Belongs to the LOG family
CH57_3272	COG1943	Transposase
CH57_3273	COG3098	single-species biofilm formation
CH57_3274	COG0564	pseudouridine synthase activity
CH57_3279	COG0024	Methionine aminopeptidase
CH57_3285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH57_3286	COG0575	Belongs to the CDS family
CH57_3287	COG0750	zinc metalloprotease
CH57_3289	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH57_3293	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH57_3295	COG0587	DNA-directed DNA polymerase activity
CH57_3297	COG0346	lactoylglutathione lyase activity
CH57_3298	COG0037	tRNA processing
CH57_3300	COG4568	rho-dependent transcription termination
CH57_3302	COG4681	YaeQ
CH57_3304	COG3015	lipoprotein NlpE involved in copper resistance
CH57_3306	COG1720	tRNA m6t6A37 methyltransferase activity
CH57_3308	COG1464	Belongs to the NlpA lipoprotein family
CH57_3309	COG2011	ABC-type metal ion transport system permease component
CH57_3311	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH57_3317	COG0656	L-ascorbic acid biosynthetic process
CH57_3320	COG1388	LysM domain
CH57_3320	COG0741	lytic transglycosylase activity
CH57_3322	COG2226	methyltransferase
CH57_3324	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH57_3326	COG1953	Uracil, thiamine, allantoin
CH57_3332	COG3657	addiction module killer protein
CH57_334	COG4128	Pfam Zonular occludens toxin
CH57_3342	COG0582	viral genome integration into host DNA
CH57_3343	COG1943	Transposase
CH57_3345	COG2867	negative regulation of translational initiation
CH57_3347	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH57_3348	COG0497	DNA recombination
CH57_3349	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH57_3352	COG2009	succinate dehydrogenase
CH57_3353	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH57_3354	COG1053	succinate dehydrogenase
CH57_3356	COG0567	Dehydrogenase, E1 component
CH57_3357	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH57_3359	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH57_3360	COG1271	oxidase subunit
CH57_3361	COG1294	oxidase, subunit
CH57_3362	COG4890	Cyd operon protein YbgT
CH57_3363	COG3790	cyd operon protein YbgE
CH57_3364	COG0824	Thioesterase
CH57_3365	COG0811	peptide transport
CH57_3366	COG0848	biopolymer transport protein
CH57_3367	COG3064	Membrane
CH57_3367	COG3064	Membrane
CH57_3369	COG2885	chlorophyll binding
CH57_3370	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH57_3376	COG1230	cation diffusion facilitator family transporter
CH57_3378	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH57_338	COG1609	Transcriptional regulator
CH57_3383	COG2017	converts alpha-aldose to the beta-anomer
CH57_3386	COG1085	galactose-1-phosphate uridylyltransferase
CH57_3387	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH57_3390	COG1119	ATPase activity
CH57_3391	COG3585	molybdate ion transport
CH57_3391	COG2005	Transcriptional regulator
CH57_3393	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH57_3394	COG4149	molybdate abc transporter
CH57_3396	COG0561	phosphatase activity
CH57_340	COG1879	ABC-type sugar transport system periplasmic component
CH57_3401	COG2226	methyltransferase
CH57_3402	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH57_3404	COG0556	nucleotide-excision repair
CH57_3405	COG4628	conserved protein (DUF2132)
CH57_3406	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH57_3408	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH57_341	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH57_3410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH57_3411	COG0314	molybdopterin synthase activity
CH57_3412	COG0670	Belongs to the BI1 family
CH57_3413	COG1943	Transposase
CH57_3417	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH57_3418	COG0583	DNA-binding transcription factor activity
CH57_342	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH57_3420	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH57_3421	COG2211	Major facilitator Superfamily
CH57_3422	COG1943	Transposase
CH57_3424	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH57_3426	COG1686	Belongs to the peptidase S11 family
CH57_3427	COG0277	FAD linked oxidase domain protein
CH57_3429	COG1403	HNH endonuclease
CH57_343	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH57_3431	COG2261	transglycosylase associated protein
CH57_3433	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH57_3436	COG4807	Protein conserved in bacteria
CH57_3440	COG1122	ATPase activity
CH57_3441	COG0410	ABC transporter
CH57_3444	COG2897	thiosulfate sulfurtransferase activity
CH57_3447	COG1174	glycine betaine transport
CH57_3448	COG1125	glycine betaine transport
CH57_3449	COG1174	glycine betaine transport
CH57_3450	COG0531	amino acid
CH57_3451	COG1982	Orn Lys Arg decarboxylase major
CH57_3453	COG0697	spore germination
CH57_3458	COG0814	amino acid
CH57_3461	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_3466	COG2205	protein histidine kinase activity
CH57_3466	COG0784	Response regulator, receiver
CH57_3468	COG2198	Histidine kinase
CH57_3468	COG0642	Histidine kinase
CH57_3469	COG0642	Histidine kinase
CH57_3469	COG2198	Histidine kinase
CH57_3470	COG2223	nitrite transmembrane transporter activity
CH57_3472	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CH57_3473	COG1943	Transposase
CH57_3474	COG1943	Transposase
CH57_3477	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH57_348	COG0028	Belongs to the TPP enzyme family
CH57_3485	COG3395	kinase activity
CH57_3486	COG0235	Class ii aldolase
CH57_3487	COG1349	DNA-binding transcription factor activity
CH57_3488	COG3622	Belongs to the hyi family
CH57_349	COG0440	acetolactate synthase activity
CH57_3492	COG4386	tail sheath protein
CH57_350	COG1011	Hydrolase
CH57_3500	COG3299	homolog of phage Mu protein gp47
CH57_3504	COG1737	Transcriptional regulator
CH57_3506	COG2723	6-phospho-beta-galactosidase activity
CH57_3510	COG3157	Type VI secretion system effector, Hcp
CH57_3513	COG3083	sulfuric ester hydrolase activity
CH57_3514	COG3082	Protein of unknown function (DUF1414)
CH57_3516	COG1943	Transposase
CH57_3518	COG1061	Type III restriction enzyme res subunit
CH57_3519	COG1187	pseudouridine synthase activity
CH57_3520	COG2814	Major facilitator Superfamily
CH57_3522	COG4172	Belongs to the ABC transporter superfamily
CH57_3523	COG4239	(ABC) transporter, permease
CH57_3524	COG4174	ABC transporter (Permease)
CH57_3525	COG4166	transmembrane transport
CH57_3526	COG2200	EAL domain
CH57_3528	COG0791	NLP P60 protein
CH57_3529	COG0671	phosphoesterase, PA-phosphatase related
CH57_3530	COG0523	cobalamin synthesis protein
CH57_3532	COG2186	Transcriptional regulator
CH57_3533	COG0246	Mannitol dehydrogenase
CH57_3534	COG1312	Catalyzes the dehydration of D-mannonate
CH57_3538	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_354	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH57_3543	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH57_3545	COG1129	ABC transporter
CH57_3546	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_3547	COG0494	nUDIX hydrolase
CH57_3549	COG1105	Belongs to the carbohydrate kinase PfkB family
CH57_355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH57_3550	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH57_3550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_3550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_3551	COG3710	Transcriptional regulator
CH57_3554	COG3121	Chaperone
CH57_3555	COG3188	usher protein
CH57_3557	COG2855	membrane
CH57_3558	COG0583	DNA-binding transcription factor activity
CH57_356	COG0589	response to stress
CH57_3560	COG0833	amino acid
CH57_3562	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_3564	COG4771	TonB-dependent receptor
CH57_3565	COG0625	glutathione transferase activity
CH57_3571	COG2011	ABC-type metal ion transport system permease component
CH57_3572	COG1686	Belongs to the peptidase S11 family
CH57_3573	COG0814	amino acid
CH57_3574	COG0814	amino acid
CH57_3575	COG1349	DNA-binding transcription factor activity
CH57_3576	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH57_3577	COG0671	phosphoesterase, PA-phosphatase related
CH57_3579	COG2985	domain, Protein
CH57_3579	COG0569	domain protein
CH57_3580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH57_3583	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH57_3584	COG3842	ATPase activity
CH57_3585	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH57_3586	COG1177	transmembrane transport
CH57_3589	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_3592	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_3593	COG1943	Transposase
CH57_3594	COG3009	Protein conserved in bacteria
CH57_3595	COG3008	intermembrane lipid transfer
CH57_3595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH57_3596	COG2995	paraquat-inducible protein a
CH57_3597	COG0488	(ABC) transporter
CH57_3599	COG3217	Mosc domain protein beta barrel domain protein
CH57_3599	COG0633	Ferredoxin
CH57_360	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH57_3602	COG0308	aminopeptidase N
CH57_3606	COG1448	Aminotransferase
CH57_3607	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH57_3608	COG3108	Peptidase M15
CH57_3609	COG2989	Protein conserved in bacteria
CH57_361	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH57_3610	COG1943	Transposase
CH57_3612	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CH57_3613	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH57_3614	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH57_3615	COG3173	Aminoglycoside phosphotransferase
CH57_3617	COG2835	tetraacyldisaccharide 4'-kinase activity
CH57_3618	COG1278	Cold shock
CH57_3619	COG5383	Protein conserved in bacteria
CH57_3622	COG0658	competence protein
CH57_3622	COG2333	competence protein COMEC
CH57_3625	COG0539	negative regulation of cytoplasmic translation
CH57_363	COG0531	amino acid
CH57_3630	COG5295	Hep Hag repeat protein
CH57_3630	COG5295	Hep Hag repeat protein
CH57_3631	COG0252	asparaginase activity
CH57_3632	COG1944	ATP diphosphatase activity
CH57_3633	COG2116	formate transmembrane transporter activity
CH57_3634	COG1882	Formate acetyltransferase
CH57_3636	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH57_3637	COG2814	Major facilitator Superfamily
CH57_3639	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH57_3642	COG1674	ftsk spoiiie
CH57_3642	COG3107	peptidoglycan biosynthetic process
CH57_3644	COG0492	ferredoxin-NADP+ reductase activity
CH57_3646	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH57_3648	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH57_3649	COG1943	Transposase
CH57_365	COG0745	RESPONSE REGULATOR receiver
CH57_3650	COG0542	response to heat
CH57_3652	COG1278	Cold shock
CH57_3654	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_3655	COG2990	Protein conserved in bacteria
CH57_3656	COG3593	DNA synthesis involved in DNA repair
CH57_3657	COG2431	L-lysine efflux transmembrane transporter activity
CH57_3659	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_366	COG2205	protein histidine kinase activity
CH57_3660	COG0028	Belongs to the TPP enzyme family
CH57_3661	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH57_3662	COG0702	epimerase
CH57_3663	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_3665	COG1605	Chorismate mutase
CH57_3666	COG1126	abc transporter atp-binding protein
CH57_3667	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_3668	COG4215	(ABC) transporter
CH57_3669	COG4160	amino acid transport
CH57_367	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH57_3673	COG1120	ATPase activity
CH57_3674	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_3679	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_368	COG1943	Transposase
CH57_3682	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_3685	COG1067	ATP-dependent peptidase activity
CH57_3687	COG1943	Transposase
CH57_3688	COG2885	chlorophyll binding
CH57_3688	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH57_3690	COG3070	regulator of competence-specific genes
CH57_3691	COG1289	transmembrane transporter activity
CH57_3692	COG3304	Inner membrane component domain
CH57_3693	COG0210	DNA helicase
CH57_3695	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CH57_3696	COG1832	CoA-binding protein
CH57_3700	COG2920	part of a sulfur-relay system
CH57_3707	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3709	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH57_3710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_3711	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3712	COG3425	synthase
CH57_3714	COG1024	Enoyl-CoA hydratase
CH57_3715	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3717	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH57_3718	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH57_372	COG3038	cytochrome b561
CH57_374	COG3591	Belongs to the peptidase S1B family
CH57_3745	COG0488	(ABC) transporter
CH57_3747	COG3328	transposase activity
CH57_3749	COG0303	'Molybdopterin
CH57_3751	COG1136	(ABC) transporter
CH57_3757	COG0583	DNA-binding transcription factor activity
CH57_3758	COG0477	Major facilitator Superfamily
CH57_3760	COG2311	Membrane
CH57_3763	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH57_3764	COG2949	membrane
CH57_3767	COG1346	cytolysis
CH57_3769	COG2814	Major facilitator Superfamily
CH57_377	COG1643	Atp-dependent helicase
CH57_3775	COG1943	Transposase
CH57_3777	COG0489	protein tyrosine kinase activity
CH57_3780	COG2982	Protein involved in outer membrane biogenesis
CH57_3781	COG1253	flavin adenine dinucleotide binding
CH57_3782	COG4114	ferric iron reductase
CH57_3783	COG0076	glutamate decarboxylase activity
CH57_3784	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH57_3787	COG1120	ATPase activity
CH57_3788	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_3789	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_379	COG2390	Transcriptional regulator
CH57_3790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH57_3793	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH57_3794	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH57_3796	COG0140	phosphoribosyl-ATP diphosphatase activity
CH57_3796	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH57_3799	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CH57_38	COG5002	protein histidine kinase activity
CH57_380	COG0246	Mannitol dehydrogenase
CH57_3800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH57_3800	COG0131	Imidazoleglycerol-phosphate dehydratase
CH57_3802	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH57_3804	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_3806	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_3807	COG1129	ABC transporter
CH57_3808	COG1129	ABC transporter
CH57_3809	COG0371	Dehydrogenase
CH57_381	COG3784	Protein of unknown function (DUF1318)
CH57_3811	COG0531	amino acid
CH57_3812	COG2925	Exonuclease
CH57_3815	COG3328	transposase activity
CH57_3816	COG1470	cell adhesion involved in biofilm formation
CH57_3816	COG1388	LysM domain
CH57_3817	COG3328	transposase activity
CH57_3818	COG2271	Major facilitator Superfamily
CH57_3819	COG3011	Protein conserved in bacteria
CH57_3820	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3822	COG4948	Mandelate Racemase Muconate Lactonizing
CH57_3826	COG0534	Mate efflux family protein
CH57_383	COG2911	Protein conserved in bacteria
CH57_3830	COG3122	Protein conserved in bacteria
CH57_3835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH57_384	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH57_3840	COG2223	nitrite transmembrane transporter activity
CH57_3842	COG3328	transposase activity
CH57_3845	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH57_3846	COG3328	transposase activity
CH57_3847	COG1530	ribonuclease E activity
CH57_3848	COG0564	pseudouridine synthase activity
CH57_3849	COG1943	Transposase
CH57_385	COG3187	Heat shock protein
CH57_3851	COG1399	metal-binding, possibly nucleic acid-binding protein
CH57_3852	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH57_3856	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3858	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_3859	COG1943	Transposase
CH57_386	COG3042	response to heat
CH57_3860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH57_3861	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH57_3863	COG0470	DNA polymerase III
CH57_3864	COG0084	hydrolase, TatD family'
CH57_3865	COG1263	PTS System
CH57_3865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_3866	COG1943	Transposase
CH57_3867	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH57_3868	COG0537	adenosine 5'-monophosphoramidase activity
CH57_3869	COG5633	Lipoprotein
CH57_387	COG1285	pathogenesis
CH57_3872	COG1472	Belongs to the glycosyl hydrolase 3 family
CH57_3874	COG1252	NADH dehydrogenase
CH57_3877	COG3328	transposase activity
CH57_3882	COG3134	Outer membrane lipoprotein
CH57_3883	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH57_3884	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH57_3886	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH57_3888	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH57_389	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH57_389	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH57_389	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH57_389	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH57_3890	COG2850	peptidyl-arginine hydroxylation
CH57_3892	COG0745	RESPONSE REGULATOR receiver
CH57_3894	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH57_3898	COG1187	pseudouridine synthase activity
CH57_3899	COG0538	isocitrate dehydrogenase activity
CH57_3902	COG0840	transmembrane signaling receptor activity
CH57_3903	COG0702	epimerase
CH57_3904	COG1733	regulation of RNA biosynthetic process
CH57_3909	COG1522	sequence-specific DNA binding
CH57_3911	COG0604	alcohol dehydrogenase
CH57_3911	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3911	COG3321	synthase
CH57_3913	COG1278	Cold shock
CH57_3915	COG0840	transmembrane signaling receptor activity
CH57_3916	COG0840	transmembrane signaling receptor activity
CH57_3917	COG1285	pathogenesis
CH57_392	COG0657	acetylesterase activity
CH57_392	COG2755	lipolytic protein G-D-S-L family
CH57_3922	COG1360	Flagellar Motor Protein
CH57_3923	COG2198	Histidine kinase
CH57_3923	COG0643	Histidine kinase
CH57_3924	COG0835	chemotaxis
CH57_3925	COG2271	Major facilitator Superfamily
CH57_3926	COG0251	oxidation-reduction process
CH57_3928	COG2964	Protein conserved in bacteria
CH57_3932	COG0840	transmembrane signaling receptor activity
CH57_3935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH57_3937	COG0745	RESPONSE REGULATOR receiver
CH57_3938	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH57_3939	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH57_3941	COG5295	Hep Hag repeat protein
CH57_3944	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH57_395	COG4166	transmembrane transport
CH57_3956	COG3121	Chaperone
CH57_396	COG2866	Carboxypeptidase
CH57_3960	COG3008	intermembrane lipid transfer
CH57_3961	COG2995	paraquat-inducible protein a
CH57_3962	COG1956	GAF domain-containing protein
CH57_3964	COG0793	Belongs to the peptidase S41A family
CH57_3967	COG3539	Fimbrial protein
CH57_3968	COG3121	Chaperone
CH57_397	COG4948	Mandelate Racemase Muconate Lactonizing
CH57_3971	COG3121	Chaperone
CH57_3972	COG2814	Major facilitator Superfamily
CH57_3973	COG0823	Involved in the tonB-independent uptake of proteins
CH57_3975	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH57_3977	COG1988	membrane-bound metal-dependent
CH57_3978	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH57_3979	COG1653	transport
CH57_398	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH57_3980	COG3842	ATPase activity
CH57_3981	COG0395	ABC-type sugar transport system, permease component
CH57_3982	COG1175	transmembrane transport
CH57_3984	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_3986	COG1917	Cupin 2, conserved barrel domain protein
CH57_3987	COG3328	transposase activity
CH57_399	COG1943	Transposase
CH57_3996	COG1132	(ABC) transporter
CH57_3998	COG2207	Transcriptional regulator
CH57_4005	COG1113	amino acid transport
CH57_4008	COG1278	Cold shock
CH57_4010	COG2226	methyltransferase
CH57_4012	COG3447	MASE1 domain protein
CH57_4012	COG5001	Diguanylate cyclase
CH57_4012	COG5002	protein histidine kinase activity
CH57_4016	COG3716	PTS system mannose fructose sorbose family IID component
CH57_4017	COG3715	PTS system
CH57_4018	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_4018	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_4019	COG1253	flavin adenine dinucleotide binding
CH57_4020	COG1846	Transcriptional regulator
CH57_4023	COG1012	belongs to the aldehyde dehydrogenase family
CH57_4024	COG3384	dioxygenase
CH57_4026	COG3971	2-oxopent-4-enoate hydratase activity
CH57_4029	COG2368	4-hydroxyphenylacetate
CH57_4030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH57_4031	COG1760	l-serine dehydratase
CH57_4036	COG0513	Belongs to the DEAD box helicase family
CH57_4037	COG3141	response to X-ray
CH57_404	COG3106	COG3106 Predicted ATPase
CH57_4040	COG1770	oligopeptidase
CH57_4043	COG1528	Iron-storage protein
CH57_4044	COG2372	response to copper ion
CH57_4049	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH57_4050	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH57_4053	COG1943	Transposase
CH57_4055	COG3418	PFAM FlgN family protein
CH57_4056	COG2747	anti-sigma28 factor FlgM
CH57_4058	COG1815	bacterial-type flagellum-dependent cell motility
CH57_4059	COG1558	bacterial-type flagellum-dependent cell motility
CH57_406	COG1983	PspC domain protein
CH57_4060	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH57_4061	COG1749	Flagellar hook protein flgE
CH57_4063	COG4786	Flagellar basal body rod
CH57_4067	COG1256	bacterial-type flagellum assembly
CH57_4069	COG2390	Transcriptional regulator
CH57_4070	COG3347	Dehydrogenase
CH57_4070	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_4072	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_4074	COG1129	ABC transporter
CH57_4075	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_4076	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_408	COG1842	Phage shock protein A
CH57_4080	COG1987	bacterial-type flagellum assembly
CH57_4085	COG1580	Controls the rotational direction of flagella during chemotaxis
CH57_4087	COG2882	bacterial-type flagellum organization
CH57_4088	COG1157	protein secretion by the type III secretion system
CH57_409	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH57_4090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH57_4092	COG1677	Flagellar hook-basal body complex protein FliE
CH57_4095	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH57_4096	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH57_4097	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH57_410	COG1943	Transposase
CH57_4103	COG1191	sigma factor activity
CH57_4105	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CH57_411	COG4166	transmembrane transport
CH57_4111	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH57_4111	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH57_4111	COG0506	proline dehydrogenase activity
CH57_4116	COG2837	iron assimilation
CH57_4119	COG1113	amino acid transport
CH57_412	COG4168	peptide transport system, permease
CH57_4123	COG3136	membrane protein required for alginate biosynthesis
CH57_4125	COG2197	response regulator
CH57_413	COG4171	peptide transport system, permease
CH57_4148	COG3328	transposase activity
CH57_4149	COG3328	transposase activity
CH57_415	COG4172	Belongs to the ABC transporter superfamily
CH57_4156	COG0673	inositol 2-dehydrogenase activity
CH57_4158	COG1175	transmembrane transport
CH57_416	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH57_416	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH57_4160	COG1475	DNA binding
CH57_4176	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH57_4178	COG3344	reverse transcriptase
CH57_418	COG3104	oligopeptide transport
CH57_4180	COG3328	transposase activity
CH57_4193	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH57_4195	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH57_4195	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH57_4202	COG3941	tape measure
CH57_4220	COG1475	DNA binding
CH57_4221	COG1475	DNA binding
CH57_4222	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH57_423	COG0625	glutathione transferase activity
CH57_4231	COG1943	Transposase
CH57_4237	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH57_4248	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH57_4250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH57_4266	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CH57_427	COG3895	Periplasmic Protein
CH57_429	COG3133	Outer membrane lipoprotein
CH57_431	COG4989	oxidoreductase activity
CH57_432	COG3313	Fe-S protein
CH57_433	COG2194	sulfuric ester hydrolase activity
CH57_434	COG1309	transcriptional regulator
CH57_435	COG1902	pentaerythritol trinitrate reductase activity
CH57_437	COG0346	lactoylglutathione lyase activity
CH57_438	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH57_439	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH57_441	COG0791	NLP P60 protein
CH57_442	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH57_445	COG0583	DNA-binding transcription factor activity
CH57_446	COG2814	Major facilitator Superfamily
CH57_447	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH57_448	COG0307	riboflavin synthase, alpha
CH57_453	COG4238	major outer membrane lipoprotein
CH57_454	COG1943	Transposase
CH57_458	COG1376	ErfK ybiS ycfS ynhG family protein
CH57_458	COG1388	LysM domain
CH57_461	COG0719	Fe-S assembly protein
CH57_462	COG0396	ATPase activity
CH57_463	COG0719	Fe-S assembly protein
CH57_464	COG0316	Belongs to the HesB IscA family
CH57_465	COG2050	protein possibly involved in aromatic compounds catabolism
CH57_466	COG0247	lactate metabolic process
CH57_466	COG0277	FAD linked oxidase domain protein
CH57_467	COG0628	permease
CH57_468	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH57_468	COG0574	Belongs to the PEP-utilizing enzyme family
CH57_474	COG0791	NLP P60 protein
CH57_482	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CH57_483	COG0386	Belongs to the glutathione peroxidase family
CH57_486	COG0776	regulation of translation
CH57_487	COG0072	phenylalanine-tRNA ligase activity
CH57_487	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH57_488	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH57_49	COG0012	GTP binding
CH57_493	COG4249	Peptidase C14 caspase catalytic subunit p20
CH57_497	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH57_498	COG1121	(ABC) transporter
CH57_499	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH57_500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH57_503	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_504	COG3328	transposase activity
CH57_507	COG0628	permease
CH57_511	COG2771	luxR family
CH57_512	COG3916	Acyl-homoserine-lactone synthase
CH57_513	COG0583	DNA-binding transcription factor activity
CH57_515	COG0477	Major facilitator Superfamily
CH57_517	COG0667	Aldo Keto reductase
CH57_52	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH57_522	COG1203	CRISPR-associated helicase, Cas3
CH57_523	COG1518	maintenance of DNA repeat elements
CH57_524	COG0668	transmembrane transport
CH57_528	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH57_529	COG0395	ABC-type sugar transport system, permease component
CH57_532	COG1609	Transcriptional regulator
CH57_534	COG3842	ATPase activity
CH57_536	COG3210	domain, Protein
CH57_540	COG3210	domain, Protein
CH57_543	COG3210	domain, Protein
CH57_544	COG2831	hemolysin activation secretion protein
CH57_545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_546	COG4638	Rieske (2fe-2S)
CH57_547	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH57_548	COG0473	3-isopropylmalate dehydrogenase activity
CH57_549	COG0583	DNA-binding transcription factor activity
CH57_550	COG1609	Transcriptional regulator
CH57_551	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_552	COG1129	ABC transporter
CH57_553	COG1879	ABC-type sugar transport system periplasmic component
CH57_554	COG1063	alcohol dehydrogenase
CH57_558	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH57_564	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_565	COG0765	amino acid transport
CH57_566	COG1126	abc transporter atp-binding protein
CH57_57	COG2890	protein-(glutamine-N5) methyltransferase activity
CH57_572	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH57_575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH57_578	COG1169	isochorismate synthase
CH57_58	COG3094	Invasion gene expression up-regulator, SirB
CH57_580	COG4575	ribosome binding
CH57_582	COG0129	dihydroxy-acid dehydratase activity
CH57_585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH57_586	COG1609	Transcriptional regulator
CH57_588	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_589	COG3265	gluconokinase activity
CH57_59	COG2912	Transglutaminase-like superfamily
CH57_590	COG2731	YhcH YjgK YiaL family protein
CH57_593	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH57_594	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH57_596	COG0839	Belongs to the complex I subunit 6 family
CH57_599	COG1034	ATP synthesis coupled electron transport
CH57_601	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CH57_603	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH57_605	COG0583	DNA-binding transcription factor activity
CH57_606	COG0436	Aminotransferase
CH57_608	COG0471	metal ion transport
CH57_608	COG0490	domain, Protein
CH57_609	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_61	COG1943	Transposase
CH57_613	COG0280	phosphate acetyltransferase
CH57_613	COG0857	belongs to the CobB CobQ family
CH57_614	COG1609	Transcriptional regulator
CH57_617	COG3328	transposase activity
CH57_619	COG4953	penicillin-binding protein 1C
CH57_62	COG0659	secondary active sulfate transmembrane transporter activity
CH57_620	COG2373	Large extracellular alpha-helical protein
CH57_626	COG3962	Belongs to the TPP enzyme family
CH57_627	COG0673	inositol 2-dehydrogenase activity
CH57_628	COG0673	inositol 2-dehydrogenase activity
CH57_629	COG1879	ABC-type sugar transport system periplasmic component
CH57_630	COG1129	ABC transporter
CH57_631	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_632	COG0673	inositol 2-dehydrogenase activity
CH57_633	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_635	COG3718	enzyme involved in inositol metabolism
CH57_637	COG5265	(ABC) transporter
CH57_642	COG2197	response regulator
CH57_644	COG1278	Cold shock
CH57_645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH57_646	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH57_65	COG0659	secondary active sulfate transmembrane transporter activity
CH57_650	COG1686	Belongs to the peptidase S11 family
CH57_651	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH57_652	COG0772	Belongs to the SEDS family
CH57_653	COG0768	penicillin binding
CH57_655	COG0799	negative regulation of ribosome biogenesis
CH57_657	COG1466	dna polymerase III delta subunit
CH57_660	COG2888	peptidyl-tyrosine sulfation
CH57_661	COG1126	abc transporter atp-binding protein
CH57_662	COG0765	amino acid transport
CH57_663	COG0765	amino acid transport
CH57_665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH57_666	COG4535	Mg2 and Co2 transporter CorC
CH57_668	COG1702	phosphate starvation-inducible protein PhoH
CH57_670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH57_676	COG0367	asparagine synthase
CH57_677	COG0647	UMP catabolic process
CH57_678	COG1846	Transcriptional regulator
CH57_678	COG1940	carbohydrate kinase activity
CH57_679	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH57_681	COG2190	(PTS) system
CH57_681	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_681	COG1263	PTS System
CH57_682	COG1943	Transposase
CH57_687	COG0735	belongs to the Fur family
CH57_69	COG3833	ABC-type maltose transport systems, permease component
CH57_691	COG0596	Alpha beta hydrolase
CH57_693	COG2963	transposase activity
CH57_694	COG0582	viral genome integration into host DNA
CH57_698	COG2113	Glycine betaine
CH57_699	COG4176	ABC-type proline glycine betaine transport system permease component
CH57_70	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH57_700	COG4175	Glycine betaine
CH57_701	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH57_709	COG3328	transposase activity
CH57_711	COG1278	Cold shock
CH57_712	COG0747	negative chemotaxis
CH57_714	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_715	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH57_716	COG1124	(ABC) transporter
CH57_72	COG1943	Transposase
CH57_723	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH57_725	COG4413	Urea transporter
CH57_726	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH57_728	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH57_729	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH57_73	COG3842	ATPase activity
CH57_730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH57_731	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH57_732	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH57_733	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH57_734	COG1917	Cupin 2, conserved barrel domain protein
CH57_734	COG2169	Transcriptional regulator
CH57_738	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH57_739	COG0033	Phosphoglucomutase
CH57_74	COG0584	glycerophosphoryl diester phosphodiesterase
CH57_743	COG0745	RESPONSE REGULATOR receiver
CH57_744	COG2205	protein histidine kinase activity
CH57_749	COG3272	Protein of unknown function (DUF1722)
CH57_75	COG1940	carbohydrate kinase activity
CH57_751	COG5212	phosphodiesterase
CH57_752	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH57_754	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH57_755	COG1984	allophanate hydrolase subunit 2
CH57_766	COG0513	Belongs to the DEAD box helicase family
CH57_768	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH57_770	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH57_771	COG3026	antisigma factor binding
CH57_772	COG3086	response to oxidative stress
CH57_775	COG0681	Belongs to the peptidase S26 family
CH57_78	COG3381	protein complex oligomerization
CH57_783	COG3501	Rhs element vgr protein
CH57_789	COG2824	Alkylphosphonate utilization operon protein PhnA
CH57_791	COG1704	LemA family
CH57_795	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH57_796	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH57_797	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH57_799	COG1138	Cytochrome C-type biogenesis protein
CH57_800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH57_801	COG3088	subunit of a heme lyase
CH57_801	COG4235	cytochrome complex assembly
CH57_802	COG4235	cytochrome complex assembly
CH57_802	COG3088	subunit of a heme lyase
CH57_805	COG3691	Protein conserved in bacteria
CH57_808	COG2062	phosphohistidine phosphatase, SixA
CH57_81	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH57_810	COG2890	protein-(glutamine-N5) methyltransferase activity
CH57_812	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CH57_813	COG0730	response to heat
CH57_814	COG3101	peptidyl-lysine hydroxylation
CH57_817	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_818	COG1794	racemase activity, acting on amino acids and derivatives
CH57_82	COG0673	inositol 2-dehydrogenase activity
CH57_821	COG0697	spore germination
CH57_824	COG1943	Transposase
CH57_825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH57_827	COG0586	Pfam SNARE associated Golgi protein
CH57_829	COG0285	dihydrofolate synthase activity
CH57_83	COG0728	peptidoglycan biosynthetic process
CH57_830	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH57_831	COG1286	toxin biosynthetic process
CH57_832	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH57_833	COG0163	prenyltransferase activity
CH57_834	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_835	COG4215	(ABC) transporter
CH57_836	COG4160	amino acid transport
CH57_837	COG4598	ABC transporter
CH57_838	COG1090	epimerase
CH57_840	COG0622	Phosphoesterase
CH57_841	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH57_842	COG3037	sugar-specific permease SgaT UlaA
CH57_843	COG3328	transposase activity
CH57_844	COG4953	penicillin-binding protein 1C
CH57_845	COG3423	Transcriptional regulator
CH57_854	COG2850	peptidyl-arginine hydroxylation
CH57_855	COG3328	transposase activity
CH57_860	COG0656	L-ascorbic acid biosynthetic process
CH57_861	COG0667	Aldo Keto reductase
CH57_867	COG2453	phosphatase
CH57_867	COG0671	phosphoesterase, PA-phosphatase related
CH57_868	COG2267	carboxylic ester hydrolase activity
CH57_87	COG3102	Protein conserved in bacteria
CH57_870	COG4589	Belongs to the CDS family
CH57_871	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH57_879	COG2501	S4 domain
CH57_880	COG1943	Transposase
CH57_883	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH57_884	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH57_888	COG0581	inorganic phosphate transmembrane transporter activity
CH57_890	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH57_891	COG0248	Ppx GppA phosphatase
CH57_892	COG2239	Acts as a magnesium transporter
CH57_893	COG0443	Heat shock 70 kDa protein
CH57_894	COG1177	transmembrane transport
CH57_895	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH57_897	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH57_899	COG3842	ATPase activity
CH57_904	COG2205	protein histidine kinase activity
CH57_905	COG0745	RESPONSE REGULATOR receiver
CH57_906	COG3422	double-strand break repair
CH57_91	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH57_912	COG0351	phosphomethylpyrimidine kinase
CH57_915	COG3328	transposase activity
CH57_92	COG1801	Protein of unknown function DUF72
CH57_923	COG1943	Transposase
CH57_925	COG0517	IMP dehydrogenase activity
CH57_925	COG0516	GMP reductase activity
CH57_927	COG1645	bacterial-type flagellum-dependent swarming motility
CH57_930	COG1943	Transposase
CH57_931	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH57_932	COG2976	Protein conserved in bacteria
CH57_94	COG0494	nUDIX hydrolase
CH57_940	COG3468	outer membrane autotransporter barrel domain protein
CH57_941	COG3468	outer membrane autotransporter barrel domain protein
CH57_945	COG2975	iron-sulfur cluster assembly
CH57_946	COG0633	Ferredoxin
CH57_947	COG0443	Heat shock 70 kDa protein
CH57_950	COG0822	iron-sulfur transferase activity
CH57_951	COG1104	cysteine desulfurase activity
CH57_954	COG0483	inositol monophosphate 1-phosphatase activity
CH57_955	COG1943	Transposase
CH57_956	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH57_957	COG3683	transport system, periplasmic component
CH57_958	COG2814	Major facilitator Superfamily
CH57_959	COG3711	transcriptional antiterminator
CH57_962	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_962	COG1017	nitric oxide dioxygenase activity
CH57_965	COG0347	Belongs to the P(II) protein family
CH57_966	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH57_966	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH57_967	COG2204	response regulator
CH57_968	COG3170	Tfp pilus assembly protein FimV
CH57_969	COG2205	protein histidine kinase activity
CH57_970	COG1943	Transposase
CH57_976	COG0590	tRNA wobble adenosine to inosine editing
CH57_977	COG0560	Phosphoserine phosphatase
CH57_979	COG1737	Transcriptional regulator
CH57_980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_981	COG1943	Transposase
CH57_983	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH57_99	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH57_994	COG3188	usher protein
CH57_995	COG3328	transposase activity
CH57_996	COG3188	usher protein
CH57_997	COG3121	Chaperone