locus-tag	class	description
CH56_100	COG1464	Belongs to the NlpA lipoprotein family
CH56_1002	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH56_1004	COG0471	metal ion transport
CH56_1005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH56_1006	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH56_1007	COG0583	DNA-binding transcription factor activity
CH56_1010	COG3152	Membrane
CH56_1012	COG1494	fructose-1,6-bisphosphatase
CH56_1013	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH56_1014	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH56_102	COG1720	tRNA m6t6A37 methyltransferase activity
CH56_1022	COG1575	Belongs to the MenA family. Type 1 subfamily
CH56_1025	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH56_1026	COG1609	Transcriptional regulator
CH56_1027	COG1943	Transposase
CH56_1028	COG0678	peroxiredoxin activity
CH56_1028	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH56_104	COG3015	lipoprotein NlpE involved in copper resistance
CH56_1043	COG2801	Transposase and inactivated derivatives
CH56_1048	COG2805	Type II/IV secretion system protein
CH56_1049	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH56_1050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH56_1051	COG0762	integral membrane protein
CH56_1053	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH56_1054	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH56_1055	COG3328	transposase activity
CH56_1056	COG1073	alpha beta
CH56_1056	COG3064	Membrane
CH56_1056	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH56_1059	COG2066	Belongs to the glutaminase family
CH56_106	COG4681	YaeQ
CH56_1060	COG3171	Protein conserved in bacteria
CH56_1062	COG1194	a g-specific adenine glycosylase
CH56_1066	COG4774	siderophore transport
CH56_1067	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_1068	COG1129	ABC transporter
CH56_1069	COG1879	ABC-type sugar transport system periplasmic component
CH56_1070	COG1982	Orn Lys Arg decarboxylase major
CH56_1074	COG1662	PFAM IS1 transposase
CH56_108	COG4568	rho-dependent transcription termination
CH56_1092	COG2771	luxR family
CH56_1093	COG3916	Acyl-homoserine-lactone synthase
CH56_1094	COG3328	transposase activity
CH56_110	COG0037	tRNA processing
CH56_1105	COG2211	Major facilitator Superfamily
CH56_1106	COG2801	Transposase and inactivated derivatives
CH56_1108	COG3133	Outer membrane lipoprotein
CH56_1109	COG3133	Outer membrane lipoprotein
CH56_111	COG0346	lactoylglutathione lyase activity
CH56_1114	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH56_1115	COG1191	sigma factor activity
CH56_1120	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH56_1122	COG3328	transposase activity
CH56_1126	COG3710	Transcriptional regulator
CH56_113	COG0587	DNA-directed DNA polymerase activity
CH56_1130	COG1256	bacterial-type flagellum assembly
CH56_1132	COG1706	bacterial-type flagellum-dependent cell motility
CH56_1133	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH56_1134	COG4786	Flagellar basal body rod
CH56_1135	COG4787	bacterial-type flagellum-dependent cell motility
CH56_1136	COG1749	Flagellar hook protein flgE
CH56_1137	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH56_1138	COG1558	bacterial-type flagellum-dependent cell motility
CH56_1139	COG1815	bacterial-type flagellum-dependent cell motility
CH56_1140	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH56_1149	COG2204	response regulator
CH56_115	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH56_1154	COG1987	bacterial-type flagellum assembly
CH56_1155	COG1684	flagellar biosynthetic protein fliR
CH56_1156	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH56_1161	COG4592	Periplasmic binding protein
CH56_1168	COG4964	Belongs to the GSP D family
CH56_1169	COG4964	Belongs to the GSP D family
CH56_1179	COG0848	biopolymer transport protein
CH56_1181	COG0811	peptide transport
CH56_1182	COG0626	cystathionine gamma-synthase activity
CH56_1183	COG0586	Pfam SNARE associated Golgi protein
CH56_1184	COG1979	alcohol dehydrogenase
CH56_1185	COG0656	L-ascorbic acid biosynthetic process
CH56_1188	COG2132	Multicopper oxidase
CH56_1189	COG0204	Acyl-transferase
CH56_119	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH56_1190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH56_1191	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH56_1192	COG0583	DNA-binding transcription factor activity
CH56_1193	COG0187	DNA topoisomerase II activity
CH56_1194	COG3150	esterase
CH56_1195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH56_1196	COG3151	Protein conserved in bacteria
CH56_1197	COG0494	nUDIX hydrolase
CH56_1198	COG1538	Outer membrane efflux protein
CH56_1202	COG0754	glutathionylspermidine amidase activity
CH56_1203	COG3384	dioxygenase
CH56_1207	COG0531	amino acid
CH56_121	COG0750	zinc metalloprotease
CH56_1210	COG3025	triphosphatase activity
CH56_1211	COG4991	sh3 domain protein
CH56_1214	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH56_1218	COG0358	DNA primase activity
CH56_1219	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH56_122	COG0575	Belongs to the CDS family
CH56_123	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH56_1233	COG0582	viral genome integration into host DNA
CH56_1234	COG2963	transposase activity
CH56_1236	COG0596	Alpha beta hydrolase
CH56_1240	COG0735	belongs to the Fur family
CH56_1252	COG0367	asparagine synthase
CH56_1253	COG0647	UMP catabolic process
CH56_1254	COG1846	Transcriptional regulator
CH56_1254	COG1940	carbohydrate kinase activity
CH56_1255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH56_1257	COG1263	PTS System
CH56_1257	COG2190	(PTS) system
CH56_1257	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH56_1259	COG1609	Transcriptional regulator
CH56_1262	COG3037	sugar-specific permease SgaT UlaA
CH56_1263	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH56_1264	COG0622	Phosphoesterase
CH56_1266	COG1090	epimerase
CH56_1267	COG4598	ABC transporter
CH56_1268	COG4160	amino acid transport
CH56_1269	COG4215	(ABC) transporter
CH56_1270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_1271	COG0163	prenyltransferase activity
CH56_1272	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH56_1273	COG1286	toxin biosynthetic process
CH56_1274	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH56_1275	COG0285	dihydrofolate synthase activity
CH56_1277	COG0586	Pfam SNARE associated Golgi protein
CH56_1279	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH56_1280	COG1943	Transposase
CH56_1283	COG0697	spore germination
CH56_1286	COG1794	racemase activity, acting on amino acids and derivatives
CH56_1287	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH56_129	COG0024	Methionine aminopeptidase
CH56_1290	COG3101	peptidyl-lysine hydroxylation
CH56_1291	COG0730	response to heat
CH56_1294	COG2890	protein-(glutamine-N5) methyltransferase activity
CH56_1296	COG2062	phosphohistidine phosphatase, SixA
CH56_1299	COG3691	Protein conserved in bacteria
CH56_13	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH56_130	COG0024	Methionine aminopeptidase
CH56_1302	COG3088	subunit of a heme lyase
CH56_1302	COG4235	cytochrome complex assembly
CH56_1303	COG3088	subunit of a heme lyase
CH56_1303	COG4235	cytochrome complex assembly
CH56_1304	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH56_1305	COG1138	Cytochrome C-type biogenesis protein
CH56_1307	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH56_1308	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH56_1309	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH56_1313	COG1704	LemA family
CH56_1315	COG3328	transposase activity
CH56_1316	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH56_1319	COG3328	transposase activity
CH56_1328	COG1943	Transposase
CH56_1330	COG0517	IMP dehydrogenase activity
CH56_1330	COG0516	GMP reductase activity
CH56_1332	COG1645	bacterial-type flagellum-dependent swarming motility
CH56_1335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH56_1336	COG2976	Protein conserved in bacteria
CH56_1344	COG3468	outer membrane autotransporter barrel domain protein
CH56_1345	COG3468	outer membrane autotransporter barrel domain protein
CH56_1349	COG2975	iron-sulfur cluster assembly
CH56_135	COG0564	pseudouridine synthase activity
CH56_1350	COG0633	Ferredoxin
CH56_1351	COG0443	Heat shock 70 kDa protein
CH56_1354	COG0822	iron-sulfur transferase activity
CH56_1355	COG1104	cysteine desulfurase activity
CH56_1358	COG0483	inositol monophosphate 1-phosphatase activity
CH56_1359	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH56_136	COG3098	single-species biofilm formation
CH56_1360	COG3683	transport system, periplasmic component
CH56_1361	COG2814	Major facilitator Superfamily
CH56_1362	COG3711	transcriptional antiterminator
CH56_1365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH56_1365	COG1017	nitric oxide dioxygenase activity
CH56_1366	COG2188	Transcriptional regulator
CH56_1373	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH56_1375	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH56_1380	COG1515	deoxyribonuclease V activity
CH56_1381	COG3068	Protein conserved in bacteria
CH56_1384	COG0151	Belongs to the GarS family
CH56_1394	COG1879	ABC-type sugar transport system periplasmic component
CH56_1395	COG1129	ABC transporter
CH56_1396	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_1398	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_1399	COG3085	chromosome segregation
CH56_14	COG1805	sodium ion transport
CH56_140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH56_1402	COG3978	acetolactate synthase activity
CH56_1403	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH56_1411	COG0583	DNA-binding transcription factor activity
CH56_1418	COG3121	Chaperone
CH56_1421	COG3121	Chaperone
CH56_1424	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH56_1428	COG3118	belongs to the thioredoxin family
CH56_1429	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH56_1430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH56_1431	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH56_1432	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH56_1433	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH56_1434	COG1088	dTDP-glucose 4,6-dehydratase activity
CH56_1435	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH56_1436	COG0456	acetyltransferase
CH56_1437	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH56_1438	COG2244	polysaccharide biosynthetic process
CH56_1442	COG1113	amino acid transport
CH56_1451	COG3071	HemY protein
CH56_1452	COG2959	enzyme of heme biosynthesis
CH56_1453	COG1587	Uroporphyrinogen-III synthase
CH56_1455	COG3072	Adenylate cyclase
CH56_1457	COG5567	small periplasmic lipoprotein
CH56_1459	COG3159	Protein conserved in bacteria
CH56_1460	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH56_1461	COG1011	Hydrolase
CH56_1462	COG0210	DNA helicase
CH56_1464	COG5441	Belongs to the UPF0261 family
CH56_1465	COG5564	TIM-barrel signal transduction protein
CH56_1467	COG0598	Magnesium transport protein CorA
CH56_1469	COG2050	protein possibly involved in aromatic compounds catabolism
CH56_1470	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH56_1471	COG0514	ATP-dependent DNA helicase (RecQ)
CH56_1472	COG1280	lysine exporter protein (LysE YggA)
CH56_1473	COG1280	lysine exporter protein (LysE YggA)
CH56_1474	COG2267	carboxylic ester hydrolase activity
CH56_1475	COG0561	phosphatase activity
CH56_1477	COG0584	glycerophosphoryl diester phosphodiesterase
CH56_1478	COG3328	transposase activity
CH56_1479	COG0584	glycerophosphoryl diester phosphodiesterase
CH56_148	COG2814	Major facilitator Superfamily
CH56_1480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH56_1481	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH56_1483	COG0247	lactate metabolic process
CH56_1485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH56_1488	COG3714	YhhN family
CH56_149	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH56_1491	COG3776	membrane
CH56_1492	COG0742	ribosomal rna small subunit methyltransferase
CH56_1493	COG0552	protein localization to endoplasmic reticulum
CH56_1493	COG0552	protein localization to endoplasmic reticulum
CH56_1494	COG2884	Cell division ATP-binding protein ftsE
CH56_1495	COG2177	Part of the ABC transporter FtsEX involved in
CH56_1497	COG1943	Transposase
CH56_1500	COG0051	transcription antitermination factor activity, RNA binding
CH56_1505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH56_1507	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH56_1508	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH56_151	COG1846	Transcriptional regulator
CH56_1510	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH56_1511	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH56_1519	COG1841	ribosomal large subunit assembly
CH56_152	COG1566	PFAM secretion protein HlyD family protein
CH56_1521	COG0201	protein transport
CH56_1522	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH56_1525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH56_1528	COG0789	Transcriptional regulator
CH56_1529	COG3036	rescue of stalled ribosome
CH56_153	COG2814	Major facilitator Superfamily
CH56_1530	COG3328	transposase activity
CH56_1532	COG0569	domain protein
CH56_1536	COG0758	DNA mediated transformation
CH56_1538	COG0758	DNA mediated transformation
CH56_154	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH56_1540	COG0551	DNA topoisomerase type I activity
CH56_1543	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH56_155	COG3118	belongs to the thioredoxin family
CH56_1559	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH56_1560	COG2224	Isocitrate lyase
CH56_1561	COG2391	methyltransferase activity
CH56_1562	COG0425	Belongs to the sulfur carrier protein TusA family
CH56_1563	COG0583	DNA-binding transcription factor activity
CH56_1564	COG0814	amino acid
CH56_1565	COG0626	cystathionine gamma-synthase activity
CH56_1567	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH56_1568	COG4558	Periplasmic binding protein
CH56_1569	COG3720	iron ion transport
CH56_157	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH56_157	COG1042	CoA-binding domain protein
CH56_157	COG0045	succinate-CoA ligase (ADP-forming) activity
CH56_1570	COG4771	TonB-dependent receptor
CH56_1572	COG0702	epimerase
CH56_1573	COG3721	Heme iron utilization protein
CH56_1578	COG1358	cellular component organization or biogenesis
CH56_158	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH56_159	COG5544	Lipoprotein
CH56_1592	COG3121	Chaperone
CH56_16	COG0121	glutamine amidotransferase
CH56_1600	COG1943	Transposase
CH56_1602	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH56_1603	COG0360	Binds together with S18 to 16S ribosomal RNA
CH56_1605	COG1073	alpha beta
CH56_1606	COG3650	response to hydrogen peroxide
CH56_1607	COG1960	acyl-CoA dehydrogenase activity
CH56_1611	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH56_1612	COG0557	exoribonuclease II activity
CH56_1615	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH56_1616	COG0330	HflC and HflK could
CH56_1617	COG0330	HflC and HflK could
CH56_1618	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH56_1622	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH56_1623	COG0802	atpase or kinase
CH56_1624	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH56_1624	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH56_1625	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH56_1629	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH56_1632	COG3264	Mechanosensitive ion channel
CH56_1632	COG1511	domain protein
CH56_1634	COG1053	succinate dehydrogenase
CH56_1635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH56_1637	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH56_1638	COG2076	Multidrug Resistance protein
CH56_164	COG0542	response to heat
CH56_1646	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH56_1649	COG3383	formate dehydrogenase (NAD+) activity
CH56_1650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH56_1651	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH56_1651	COG0493	'glutamate synthase
CH56_1652	COG1309	transcriptional regulator
CH56_166	COG0564	pseudouridine synthase activity
CH56_1669	COG1454	alcohol dehydrogenase
CH56_167	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH56_1671	COG0629	single-stranded DNA binding
CH56_1672	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH56_1673	COG2315	Protein conserved in bacteria
CH56_1674	COG1448	Aminotransferase
CH56_1675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH56_1676	COG0305	Participates in initiation and elongation during chromosome replication
CH56_168	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH56_1689	COG0564	pseudouridine synthase activity
CH56_1690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH56_1692	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH56_1693	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH56_1698	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH56_17	COG3034	peptidoglycan biosynthetic process
CH56_170	COG1605	Chorismate mutase
CH56_170	COG0077	Prephenate dehydratase
CH56_1700	COG2966	Psort location CytoplasmicMembrane, score
CH56_1701	COG1280	lysine exporter protein (LysE YggA)
CH56_1702	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH56_1703	COG0505	Belongs to the CarA family
CH56_1705	COG1943	Transposase
CH56_1707	COG1047	Peptidyl-prolyl cis-trans
CH56_171	COG1605	Chorismate mutase
CH56_171	COG0287	Prephenate dehydrogenase
CH56_1710	COG0196	riboflavin kinase activity
CH56_1712	COG1943	Transposase
CH56_1713	COG0583	DNA-binding transcription factor activity
CH56_1717	COG1584	GPR1 FUN34 yaaH family protein
CH56_172	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH56_1720	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH56_1729	COG0745	RESPONSE REGULATOR receiver
CH56_173	COG3279	Response regulator of the LytR AlgR family
CH56_1730	COG3045	CreA protein
CH56_1733	COG3708	Transcriptional regulator
CH56_1733	COG2207	Transcriptional regulator
CH56_1734	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH56_1736	COG0741	lytic transglycosylase activity
CH56_1739	COG2199	diguanylate cyclase activity
CH56_1740	COG2885	chlorophyll binding
CH56_1741	COG0488	(ABC) transporter
CH56_1745	COG0560	Phosphoserine phosphatase
CH56_1746	COG3726	membrane protein affecting hemolysin expression
CH56_1750	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH56_1751	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH56_1752	COG0084	hydrolase, TatD family'
CH56_1753	COG4667	esterase of the alpha-beta hydrolase superfamily
CH56_1755	COG2823	Periplasmic or secreted lipoprotein
CH56_1757	COG0456	acetyltransferase
CH56_1758	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH56_176	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CH56_1762	COG3706	GGDEF domain
CH56_1766	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH56_1767	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH56_177	COG1943	Transposase
CH56_1770	COG0859	PFAM glycosyl transferase family 9
CH56_1772	COG2390	Transcriptional regulator
CH56_178	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH56_178	COG1263	PTS System
CH56_1780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH56_1780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_1780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_1781	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH56_1782	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH56_1783	COG2207	Transcriptional regulator
CH56_1784	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH56_1786	COG4269	membrane
CH56_179	COG0084	hydrolase, TatD family'
CH56_1792	COG3328	transposase activity
CH56_1797	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH56_1798	COG4137	Cytochrome C assembly protein
CH56_1799	COG4536	flavin adenine dinucleotide binding
CH56_180	COG0470	DNA polymerase III
CH56_1803	COG4536	flavin adenine dinucleotide binding
CH56_1805	COG2918	glutathione biosynthetic process
CH56_1806	COG1238	metal cluster binding
CH56_1807	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH56_1812	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH56_1813	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH56_1814	COG3328	transposase activity
CH56_1816	COG3328	transposase activity
CH56_182	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH56_1823	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH56_1824	COG2801	Transposase and inactivated derivatives
CH56_1826	COG3958	Transketolase
CH56_1827	COG3959	Transketolase, thiamine diphosphate binding domain
CH56_1828	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_1829	COG1129	ABC transporter
CH56_183	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH56_1833	COG3783	Cytochrome b(562)
CH56_1834	COG3038	cytochrome b561
CH56_1835	COG3381	protein complex oligomerization
CH56_1836	COG3302	dmso reductase anchor subunit
CH56_1837	COG0437	4 iron, 4 sulfur cluster binding
CH56_1838	COG0243	molybdopterin cofactor binding
CH56_1839	COG0235	Class ii aldolase
CH56_1840	COG1349	DNA-binding transcription factor activity
CH56_1841	COG1349	DNA-binding transcription factor activity
CH56_1843	COG1129	ABC transporter
CH56_1844	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_1845	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_1846	COG3623	hexulose-6-phosphate isomerase
CH56_1847	COG1070	Carbohydrate kinase
CH56_1848	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH56_1848	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH56_185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH56_1850	COG0024	Methionine aminopeptidase
CH56_1852	COG4771	TonB-dependent receptor
CH56_1854	COG1858	cytochrome C peroxidase
CH56_1855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_1859	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH56_1862	COG2376	Dihydroxyacetone kinase
CH56_1863	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_1864	COG1063	alcohol dehydrogenase
CH56_1865	COG0698	ribose 5-phosphate isomerase
CH56_1866	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH56_1867	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH56_1868	COG4942	peptidase
CH56_1868	COG1388	LysM domain
CH56_187	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_1873	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CH56_1876	COG0529	Catalyzes the synthesis of activated sulfate
CH56_1888	COG0720	synthase
CH56_1889	COG0602	queuosine metabolic process
CH56_1893	COG3956	TIGRFAM MazG family protein
CH56_1894	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH56_1895	COG4999	Histidine kinase
CH56_1895	COG3437	response regulator, receiver
CH56_1895	COG3850	Histidine kinase
CH56_1895	COG2205	protein histidine kinase activity
CH56_1896	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH56_1898	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH56_19	COG1960	acyl-CoA dehydrogenase activity
CH56_1900	COG2860	membrane
CH56_1904	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH56_1905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH56_1906	COG1120	ATPase activity
CH56_1907	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH56_1908	COG1643	Atp-dependent helicase
CH56_1909	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH56_191	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH56_1911	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH56_1912	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH56_1913	COG0617	tRNA 3'-terminal CCA addition
CH56_1914	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH56_1918	COG0726	polysaccharide deacetylase
CH56_1919	COG0842	Transport permease protein
CH56_192	COG1399	metal-binding, possibly nucleic acid-binding protein
CH56_1920	COG1131	(ABC) transporter
CH56_1921	COG0288	reversible hydration of carbon dioxide
CH56_1922	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH56_1924	COG2132	Multicopper oxidase
CH56_1928	COG0697	spore germination
CH56_1930	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH56_1932	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH56_1933	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH56_1934	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH56_1935	COG2186	Transcriptional regulator
CH56_1936	COG1113	amino acid transport
CH56_1937	COG3725	Membrane protein required for beta-lactamase induction
CH56_1938	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH56_194	COG0564	pseudouridine synthase activity
CH56_1940	COG4969	Belongs to the N-Me-Phe pilin family
CH56_1941	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH56_1942	COG1459	type II secretion system
CH56_1944	COG0237	dephospho-CoA kinase activity
CH56_195	COG1530	ribonuclease E activity
CH56_1953	COG0251	oxidation-reduction process
CH56_196	COG3328	transposase activity
CH56_1962	COG1289	transmembrane transporter activity
CH56_1964	COG1472	Belongs to the glycosyl hydrolase 3 family
CH56_1967	COG0395	ABC-type sugar transport system, permease component
CH56_1969	COG1653	transport
CH56_197	COG2271	Major facilitator Superfamily
CH56_1970	COG1609	Transcriptional regulator
CH56_1971	COG3459	Glycosyltransferase 36 associated
CH56_1972	COG3842	ATPase activity
CH56_1976	COG3210	domain, Protein
CH56_1977	COG3210	domain, Protein
CH56_1979	COG3210	domain, Protein
CH56_198	COG0251	oxidation-reduction process
CH56_1981	COG3210	domain, Protein
CH56_1982	COG3210	domain, Protein
CH56_1983	COG3210	domain, Protein
CH56_1984	COG2831	hemolysin activation secretion protein
CH56_1985	COG4245	von Willebrand factor, type A
CH56_1988	COG4245	von Willebrand factor, type A
CH56_1991	COG3247	response to pH
CH56_1992	COG1902	pentaerythritol trinitrate reductase activity
CH56_1992	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH56_1996	COG1451	nucleotide metabolic process
CH56_1997	COG0673	inositol 2-dehydrogenase activity
CH56_200	COG2964	Protein conserved in bacteria
CH56_2000	COG1943	Transposase
CH56_2002	COG2721	sulfolactate sulfo-lyase activity
CH56_2003	COG0246	Mannitol dehydrogenase
CH56_2004	COG0246	Mannitol dehydrogenase
CH56_2006	COG2271	Major facilitator Superfamily
CH56_2009	COG0586	Pfam SNARE associated Golgi protein
CH56_2012	COG4575	ribosome binding
CH56_2013	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH56_2015	COG2259	Doxx family
CH56_2016	COG0435	Glutathione S-transferase
CH56_2017	COG0583	DNA-binding transcription factor activity
CH56_2018	COG1741	Belongs to the pirin family
CH56_2019	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH56_2023	COG2823	Periplasmic or secreted lipoprotein
CH56_2025	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH56_2026	COG0784	Response regulator, receiver
CH56_2026	COG2198	Histidine kinase
CH56_2026	COG5002	protein histidine kinase activity
CH56_2027	COG1242	4 iron, 4 sulfur cluster binding
CH56_2028	COG0070	glutamate synthase
CH56_2028	COG0067	glutamate synthase
CH56_2028	COG0069	glutamate synthase activity
CH56_2029	COG0493	'glutamate synthase
CH56_2031	COG2969	positive regulation of protein catabolic process
CH56_2032	COG0625	glutathione transferase activity
CH56_2035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH56_2036	COG3105	Protein conserved in bacteria
CH56_2037	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH56_2038	COG1943	Transposase
CH56_2039	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH56_2041	COG5007	Belongs to the BolA IbaG family
CH56_2042	COG3113	response to antibiotic
CH56_2043	COG2854	intermembrane phospholipid transfer
CH56_2044	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH56_2045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH56_2046	COG1127	ABC transporter
CH56_2047	COG0530	calcium, potassium:sodium antiporter activity
CH56_2048	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH56_2048	COG0517	IMP dehydrogenase activity
CH56_2049	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH56_205	COG0840	transmembrane signaling receptor activity
CH56_2050	COG3117	lipopolysaccharide transmembrane transporter activity
CH56_2051	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH56_2052	COG1137	ATPase activity
CH56_2053	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH56_2055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_2057	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_206	COG0840	transmembrane signaling receptor activity
CH56_2062	COG1609	Transcriptional regulator
CH56_2063	COG1263	PTS System
CH56_2063	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH56_2064	COG0366	Alpha amylase catalytic
CH56_2065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH56_2066	COG3783	Cytochrome b(562)
CH56_2068	COG0312	modulator of DNA gyrase
CH56_207	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH56_2070	COG2732	(Barnase) inhibitor
CH56_2073	COG1012	belongs to the aldehyde dehydrogenase family
CH56_2077	COG0583	DNA-binding transcription factor activity
CH56_209	COG0745	RESPONSE REGULATOR receiver
CH56_2090	COG0312	modulator of DNA gyrase
CH56_2091	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH56_2092	COG3164	Protein of unknown function
CH56_2093	COG1530	ribonuclease E activity
CH56_2095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH56_2096	COG1792	Involved in formation and maintenance of cell shape
CH56_2097	COG1077	Cell shape determining protein MreB Mrl
CH56_2098	COG2199	diguanylate cyclase activity
CH56_2098	COG2200	EAL domain
CH56_2099	COG0604	alcohol dehydrogenase
CH56_21	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH56_210	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH56_2100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH56_2103	COG0511	ligase activity, forming carbon-carbon bonds
CH56_2104	COG0439	Biotin carboxylase
CH56_2106	COG3924	membrane
CH56_2107	COG4145	pantothenate transmembrane transporter activity
CH56_2109	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH56_211	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH56_2110	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH56_2114	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH56_2116	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH56_2117	COG3133	Outer membrane lipoprotein
CH56_2118	COG1278	Cold shock
CH56_2119	COG1278	Cold shock
CH56_212	COG5295	Hep Hag repeat protein
CH56_2123	COG0625	glutathione transferase activity
CH56_2125	COG1069	ribulokinase activity
CH56_2127	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_2128	COG1129	ABC transporter
CH56_2130	COG1560	Kdo2-lipid A biosynthetic process
CH56_2132	COG0025	NhaP-type Na H and K H
CH56_2133	COG2252	PERMEase
CH56_2134	COG3077	Addiction module antitoxin, RelB DinJ family
CH56_2137	COG1401	restriction endodeoxyribonuclease activity
CH56_2139	COG2963	transposase activity
CH56_2142	COG3328	transposase activity
CH56_215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH56_2152	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH56_2153	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH56_2154	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH56_2158	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH56_2159	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH56_2160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH56_2160	COG4651	solute:proton antiporter activity
CH56_2161	COG2223	nitrite transmembrane transporter activity
CH56_2162	COG0737	Belongs to the 5'-nucleotidase family
CH56_2163	COG0737	Belongs to the 5'-nucleotidase family
CH56_2164	COG0737	Belongs to the 5'-nucleotidase family
CH56_2167	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH56_2168	COG3735	TraB family
CH56_2169	COG2217	Heavy metal translocating P-type atpase
CH56_2170	COG0789	Transcriptional regulator
CH56_2171	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH56_2172	COG0330	HflC and HflK could
CH56_2173	COG3118	belongs to the thioredoxin family
CH56_2174	COG0300	oxidoreductase activity
CH56_2175	COG2755	lipolytic protein G-D-S-L family
CH56_2176	COG4181	ATPase activity
CH56_2177	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH56_2178	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH56_2179	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH56_2181	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH56_2184	COG2501	S4 domain
CH56_2191	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH56_2192	COG4589	Belongs to the CDS family
CH56_2194	COG2267	carboxylic ester hydrolase activity
CH56_2195	COG0671	phosphoesterase, PA-phosphatase related
CH56_2195	COG2453	phosphatase
CH56_2203	COG1943	Transposase
CH56_2205	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH56_2207	COG0735	belongs to the Fur family
CH56_2208	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH56_2210	COG0604	alcohol dehydrogenase
CH56_2213	COG2198	Histidine kinase
CH56_2213	COG0642	Histidine kinase
CH56_2215	COG2205	protein histidine kinase activity
CH56_2215	COG0784	Response regulator, receiver
CH56_2220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH56_2223	COG0814	amino acid
CH56_2228	COG0697	spore germination
CH56_2230	COG1982	Orn Lys Arg decarboxylase major
CH56_2231	COG0531	amino acid
CH56_2232	COG1174	glycine betaine transport
CH56_2233	COG1174	glycine betaine transport
CH56_2234	COG1125	glycine betaine transport
CH56_2235	COG1174	glycine betaine transport
CH56_2236	COG1732	Glycine betaine
CH56_2237	COG1732	Glycine betaine
CH56_2238	COG2897	thiosulfate sulfurtransferase activity
CH56_224	COG2113	Glycine betaine
CH56_2241	COG0410	ABC transporter
CH56_2242	COG1122	ATPase activity
CH56_2246	COG4807	Protein conserved in bacteria
CH56_2249	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH56_225	COG4176	ABC-type proline glycine betaine transport system permease component
CH56_2251	COG2261	transglycosylase associated protein
CH56_2253	COG1403	HNH endonuclease
CH56_2255	COG0277	FAD linked oxidase domain protein
CH56_2256	COG1686	Belongs to the peptidase S11 family
CH56_2258	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH56_226	COG4175	Glycine betaine
CH56_2262	COG3657	addiction module killer protein
CH56_227	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH56_2272	COG0582	viral genome integration into host DNA
CH56_2275	COG2867	negative regulation of translational initiation
CH56_2277	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH56_2278	COG0497	DNA recombination
CH56_2279	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH56_2282	COG2009	succinate dehydrogenase
CH56_2283	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH56_2284	COG1053	succinate dehydrogenase
CH56_2286	COG0567	Dehydrogenase, E1 component
CH56_2287	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH56_2289	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH56_2290	COG1271	oxidase subunit
CH56_2291	COG1294	oxidase, subunit
CH56_2292	COG4890	Cyd operon protein YbgT
CH56_2293	COG3790	cyd operon protein YbgE
CH56_2295	COG0811	peptide transport
CH56_2296	COG0848	biopolymer transport protein
CH56_2297	COG3064	Membrane
CH56_2297	COG3064	Membrane
CH56_2299	COG2885	chlorophyll binding
CH56_2300	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH56_2305	COG1230	cation diffusion facilitator family transporter
CH56_2307	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH56_2310	COG2017	converts alpha-aldose to the beta-anomer
CH56_2313	COG1085	galactose-1-phosphate uridylyltransferase
CH56_2314	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH56_2317	COG1119	ATPase activity
CH56_2318	COG2005	Transcriptional regulator
CH56_2318	COG3585	molybdate ion transport
CH56_2320	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH56_2321	COG4149	molybdate abc transporter
CH56_2323	COG0561	phosphatase activity
CH56_2329	COG2226	methyltransferase
CH56_2330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH56_2332	COG0556	nucleotide-excision repair
CH56_2333	COG4628	conserved protein (DUF2132)
CH56_2334	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH56_2336	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH56_2338	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH56_2339	COG0314	molybdopterin synthase activity
CH56_2340	COG0670	Belongs to the BI1 family
CH56_2344	COG0642	Histidine kinase
CH56_2344	COG2198	Histidine kinase
CH56_2345	COG2223	nitrite transmembrane transporter activity
CH56_2347	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CH56_235	COG1278	Cold shock
CH56_2350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH56_2359	COG3395	kinase activity
CH56_236	COG0747	negative chemotaxis
CH56_2360	COG0235	Class ii aldolase
CH56_2361	COG1349	DNA-binding transcription factor activity
CH56_2362	COG3622	Belongs to the hyi family
CH56_2366	COG4386	tail sheath protein
CH56_2374	COG3299	homolog of phage Mu protein gp47
CH56_2378	COG1737	Transcriptional regulator
CH56_238	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH56_2380	COG2723	6-phospho-beta-galactosidase activity
CH56_2384	COG3157	Type VI secretion system effector, Hcp
CH56_2387	COG3083	sulfuric ester hydrolase activity
CH56_2388	COG3082	Protein of unknown function (DUF1414)
CH56_239	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH56_2392	COG1061	Type III restriction enzyme res subunit
CH56_2393	COG1187	pseudouridine synthase activity
CH56_2394	COG2814	Major facilitator Superfamily
CH56_2396	COG4172	Belongs to the ABC transporter superfamily
CH56_2397	COG4239	(ABC) transporter, permease
CH56_2398	COG4174	ABC transporter (Permease)
CH56_2399	COG4166	transmembrane transport
CH56_240	COG1124	(ABC) transporter
CH56_2400	COG2200	EAL domain
CH56_2402	COG0791	NLP P60 protein
CH56_2403	COG0671	phosphoesterase, PA-phosphatase related
CH56_2404	COG0523	cobalamin synthesis protein
CH56_2406	COG2186	Transcriptional regulator
CH56_2407	COG0246	Mannitol dehydrogenase
CH56_2408	COG1312	Catalyzes the dehydration of D-mannonate
CH56_2412	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_2417	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH56_2419	COG1129	ABC transporter
CH56_2421	COG0494	nUDIX hydrolase
CH56_2423	COG1105	Belongs to the carbohydrate kinase PfkB family
CH56_2424	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH56_2424	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH56_2424	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH56_2425	COG3710	Transcriptional regulator
CH56_2428	COG3121	Chaperone
CH56_2429	COG3188	usher protein
CH56_2431	COG2855	membrane
CH56_2432	COG0583	DNA-binding transcription factor activity
CH56_2434	COG0833	amino acid
CH56_2436	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH56_2438	COG4771	TonB-dependent receptor
CH56_2439	COG0625	glutathione transferase activity
CH56_2445	COG2011	ABC-type metal ion transport system permease component
CH56_2446	COG1686	Belongs to the peptidase S11 family
CH56_2447	COG0814	amino acid
CH56_2449	COG1349	DNA-binding transcription factor activity
CH56_2451	COG0671	phosphoesterase, PA-phosphatase related
CH56_2453	COG0569	domain protein
CH56_2453	COG2985	domain, Protein
CH56_2454	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH56_2457	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH56_2458	COG3842	ATPase activity
CH56_2459	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH56_2460	COG1177	transmembrane transport
CH56_2463	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_2468	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH56_2469	COG1120	ATPase activity
CH56_247	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH56_2473	COG4160	amino acid transport
CH56_2474	COG4215	(ABC) transporter
CH56_2475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_2476	COG1126	abc transporter atp-binding protein
CH56_2477	COG1605	Chorismate mutase
CH56_2479	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH56_2480	COG0702	epimerase
CH56_2481	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH56_2482	COG0028	Belongs to the TPP enzyme family
CH56_2483	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH56_2485	COG2431	L-lysine efflux transmembrane transporter activity
CH56_2486	COG3593	DNA synthesis involved in DNA repair
CH56_2487	COG2990	Protein conserved in bacteria
CH56_2488	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH56_249	COG4413	Urea transporter
CH56_2491	COG1278	Cold shock
CH56_2493	COG0542	response to heat
CH56_2494	COG0542	response to heat
CH56_2496	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH56_2498	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH56_250	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH56_2501	COG0492	ferredoxin-NADP+ reductase activity
CH56_2503	COG3107	peptidoglycan biosynthetic process
CH56_2503	COG1674	ftsk spoiiie
CH56_2506	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH56_2508	COG2814	Major facilitator Superfamily
CH56_2509	COG2814	Major facilitator Superfamily
CH56_2510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH56_2515	COG2372	response to copper ion
CH56_2516	COG1528	Iron-storage protein
CH56_252	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH56_2522	COG1770	oligopeptidase
CH56_2525	COG3141	response to X-ray
CH56_2526	COG0513	Belongs to the DEAD box helicase family
CH56_253	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH56_2531	COG1760	l-serine dehydratase
CH56_2532	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH56_2533	COG2368	4-hydroxyphenylacetate
CH56_2536	COG3971	2-oxopent-4-enoate hydratase activity
CH56_2538	COG3384	dioxygenase
CH56_2539	COG1012	belongs to the aldehyde dehydrogenase family
CH56_254	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH56_2542	COG1846	Transcriptional regulator
CH56_2543	COG1253	flavin adenine dinucleotide binding
CH56_2544	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_2544	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH56_2545	COG3715	PTS system
CH56_2546	COG3716	PTS system mannose fructose sorbose family IID component
CH56_2547	COG3716	PTS system mannose fructose sorbose family IID component
CH56_255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH56_2551	COG5002	protein histidine kinase activity
CH56_2551	COG3447	MASE1 domain protein
CH56_2551	COG5001	Diguanylate cyclase
CH56_2553	COG2226	methyltransferase
CH56_2555	COG1278	Cold shock
CH56_2558	COG1113	amino acid transport
CH56_256	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH56_2565	COG2207	Transcriptional regulator
CH56_2567	COG1132	(ABC) transporter
CH56_257	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH56_2573	COG2223	nitrite transmembrane transporter activity
CH56_2578	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH56_258	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH56_2583	COG3122	Protein conserved in bacteria
CH56_2587	COG0534	Mate efflux family protein
CH56_259	COG1917	Cupin 2, conserved barrel domain protein
CH56_259	COG2169	Transcriptional regulator
CH56_2591	COG4948	Mandelate Racemase Muconate Lactonizing
CH56_2593	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_2594	COG3011	Protein conserved in bacteria
CH56_2595	COG2271	Major facilitator Superfamily
CH56_2596	COG3328	transposase activity
CH56_2597	COG1470	cell adhesion involved in biofilm formation
CH56_2597	COG1388	LysM domain
CH56_2600	COG0628	permease
CH56_2604	COG2771	luxR family
CH56_2605	COG3916	Acyl-homoserine-lactone synthase
CH56_2606	COG0583	DNA-binding transcription factor activity
CH56_2608	COG0477	Major facilitator Superfamily
CH56_2610	COG0667	Aldo Keto reductase
CH56_2615	COG1203	CRISPR-associated helicase, Cas3
CH56_2616	COG1203	CRISPR-associated helicase, Cas3
CH56_2617	COG1518	maintenance of DNA repeat elements
CH56_2618	COG0668	transmembrane transport
CH56_2622	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH56_2623	COG0395	ABC-type sugar transport system, permease component
CH56_2627	COG1609	Transcriptional regulator
CH56_2629	COG3842	ATPase activity
CH56_263	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH56_2631	COG3210	domain, Protein
CH56_2636	COG3210	domain, Protein
CH56_2639	COG3210	domain, Protein
CH56_264	COG0033	Phosphoglucomutase
CH56_2640	COG2831	hemolysin activation secretion protein
CH56_2641	COG2831	hemolysin activation secretion protein
CH56_2642	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH56_2643	COG4638	Rieske (2fe-2S)
CH56_2644	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH56_2645	COG0473	3-isopropylmalate dehydrogenase activity
CH56_2646	COG0583	DNA-binding transcription factor activity
CH56_2647	COG1609	Transcriptional regulator
CH56_2648	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_2649	COG1129	ABC transporter
CH56_2650	COG1879	ABC-type sugar transport system periplasmic component
CH56_2651	COG1063	alcohol dehydrogenase
CH56_2655	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH56_2661	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_2662	COG0765	amino acid transport
CH56_2663	COG1126	abc transporter atp-binding protein
CH56_2667	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH56_2670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH56_2673	COG1169	isochorismate synthase
CH56_2675	COG4575	ribosome binding
CH56_2677	COG0129	dihydroxy-acid dehydratase activity
CH56_268	COG0745	RESPONSE REGULATOR receiver
CH56_2680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH56_2681	COG1609	Transcriptional regulator
CH56_2683	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_2684	COG3265	gluconokinase activity
CH56_2685	COG2731	YhcH YjgK YiaL family protein
CH56_2688	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH56_2689	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH56_269	COG2205	protein histidine kinase activity
CH56_2691	COG0839	Belongs to the complex I subunit 6 family
CH56_2694	COG1034	ATP synthesis coupled electron transport
CH56_2696	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CH56_2698	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH56_2700	COG0583	DNA-binding transcription factor activity
CH56_2701	COG0436	Aminotransferase
CH56_2703	COG0471	metal ion transport
CH56_2703	COG0490	domain, Protein
CH56_2704	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH56_2708	COG0857	belongs to the CobB CobQ family
CH56_2708	COG0280	phosphate acetyltransferase
CH56_2709	COG1943	Transposase
CH56_2710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH56_2712	COG1702	phosphate starvation-inducible protein PhoH
CH56_2714	COG4535	Mg2 and Co2 transporter CorC
CH56_2715	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH56_2719	COG0765	amino acid transport
CH56_2720	COG0765	amino acid transport
CH56_2721	COG0765	amino acid transport
CH56_2722	COG1126	abc transporter atp-binding protein
CH56_2723	COG2888	peptidyl-tyrosine sulfation
CH56_2726	COG1466	dna polymerase III delta subunit
CH56_2728	COG0799	negative regulation of ribosome biogenesis
CH56_2730	COG0768	penicillin binding
CH56_2731	COG0772	Belongs to the SEDS family
CH56_2732	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH56_2733	COG1686	Belongs to the peptidase S11 family
CH56_2737	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH56_2738	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH56_2739	COG1278	Cold shock
CH56_274	COG3272	Protein of unknown function (DUF1722)
CH56_2740	COG1278	Cold shock
CH56_2741	COG2197	response regulator
CH56_2746	COG5265	(ABC) transporter
CH56_2748	COG3718	enzyme involved in inositol metabolism
CH56_2750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH56_2751	COG0673	inositol 2-dehydrogenase activity
CH56_2752	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_2753	COG1129	ABC transporter
CH56_2754	COG1879	ABC-type sugar transport system periplasmic component
CH56_2755	COG0673	inositol 2-dehydrogenase activity
CH56_2756	COG0673	inositol 2-dehydrogenase activity
CH56_2757	COG3962	Belongs to the TPP enzyme family
CH56_276	COG5212	phosphodiesterase
CH56_2764	COG2373	Large extracellular alpha-helical protein
CH56_2765	COG4953	penicillin-binding protein 1C
CH56_2766	COG3423	Transcriptional regulator
CH56_277	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH56_2775	COG2850	peptidyl-arginine hydroxylation
CH56_2776	COG3328	transposase activity
CH56_2777	COG3328	transposase activity
CH56_2782	COG1472	Belongs to the glycosyl hydrolase 3 family
CH56_2784	COG0656	L-ascorbic acid biosynthetic process
CH56_2785	COG0667	Aldo Keto reductase
CH56_279	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH56_2798	COG1739	Uncharacterized protein family UPF0029
CH56_2799	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH56_280	COG1984	allophanate hydrolase subunit 2
CH56_2800	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH56_2806	COG3328	transposase activity
CH56_2808	COG2824	Alkylphosphonate utilization operon protein PhnA
CH56_2814	COG3501	Rhs element vgr protein
CH56_2816	COG3328	transposase activity
CH56_2820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH56_2823	COG1067	ATP-dependent peptidase activity
CH56_2826	COG1882	Formate acetyltransferase
CH56_2827	COG2116	formate transmembrane transporter activity
CH56_2828	COG1944	ATP diphosphatase activity
CH56_2829	COG0252	asparaginase activity
CH56_2830	COG5295	Hep Hag repeat protein
CH56_2830	COG5295	Hep Hag repeat protein
CH56_2835	COG0539	negative regulation of cytoplasmic translation
CH56_2838	COG2333	competence protein COMEC
CH56_2838	COG0658	competence protein
CH56_2841	COG5383	Protein conserved in bacteria
CH56_2842	COG1278	Cold shock
CH56_2843	COG2835	tetraacyldisaccharide 4'-kinase activity
CH56_2845	COG3173	Aminoglycoside phosphotransferase
CH56_2846	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH56_2847	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH56_2848	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CH56_2852	COG2989	Protein conserved in bacteria
CH56_2853	COG3108	Peptidase M15
CH56_2854	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH56_2855	COG1448	Aminotransferase
CH56_2860	COG0308	aminopeptidase N
CH56_2863	COG3217	Mosc domain protein beta barrel domain protein
CH56_2863	COG0633	Ferredoxin
CH56_2865	COG0488	(ABC) transporter
CH56_2866	COG2995	paraquat-inducible protein a
CH56_2867	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH56_2867	COG3008	intermembrane lipid transfer
CH56_2868	COG3009	Protein conserved in bacteria
CH56_2869	COG1943	Transposase
CH56_2871	COG3418	PFAM FlgN family protein
CH56_2872	COG2747	anti-sigma28 factor FlgM
CH56_2874	COG1815	bacterial-type flagellum-dependent cell motility
CH56_2875	COG1558	bacterial-type flagellum-dependent cell motility
CH56_2876	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH56_2877	COG1749	Flagellar hook protein flgE
CH56_2879	COG4786	Flagellar basal body rod
CH56_2883	COG1256	bacterial-type flagellum assembly
CH56_2886	COG2882	bacterial-type flagellum organization
CH56_2887	COG1157	protein secretion by the type III secretion system
CH56_2889	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH56_2891	COG1677	Flagellar hook-basal body complex protein FliE
CH56_2894	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH56_2895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH56_2896	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH56_2907	COG1191	sigma factor activity
CH56_2909	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CH56_291	COG0513	Belongs to the DEAD box helicase family
CH56_2915	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH56_2915	COG0506	proline dehydrogenase activity
CH56_2915	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH56_2920	COG2837	iron assimilation
CH56_2923	COG1113	amino acid transport
CH56_2927	COG3136	membrane protein required for alginate biosynthesis
CH56_2929	COG2197	response regulator
CH56_293	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH56_295	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH56_2952	COG3328	transposase activity
CH56_2953	COG3328	transposase activity
CH56_2959	COG0673	inositol 2-dehydrogenase activity
CH56_296	COG3026	antisigma factor binding
CH56_2961	COG1175	transmembrane transport
CH56_2962	COG0395	ABC-type sugar transport system, permease component
CH56_297	COG3086	response to oxidative stress
CH56_2975	COG4771	TonB-dependent receptor
CH56_2976	COG1021	2,3-dihydroxybenzoate-AMP ligase
CH56_2980	COG2226	methyltransferase
CH56_2980	COG3433	isochorismatase activity
CH56_2980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH56_2983	COG1132	(ABC) transporter
CH56_2984	COG2814	Major facilitator Superfamily
CH56_2985	COG1169	isochorismate synthase
CH56_2986	COG0582	viral genome integration into host DNA
CH56_2988	COG3121	Chaperone
CH56_2990	COG3188	usher protein
CH56_2993	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_2993	COG2205	protein histidine kinase activity
CH56_2994	COG0784	Response regulator, receiver
CH56_2994	COG2198	Histidine kinase
CH56_2994	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_2994	COG2205	protein histidine kinase activity
CH56_2997	COG0427	acetyl-CoA hydrolase
CH56_2998	COG2030	dehydratase
CH56_30	COG0436	Aminotransferase
CH56_300	COG0681	Belongs to the peptidase S26 family
CH56_3006	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH56_3007	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH56_3009	COG1349	DNA-binding transcription factor activity
CH56_3010	COG2066	Belongs to the glutaminase family
CH56_3012	COG0672	)-iron permease
CH56_3016	COG1136	(ABC) transporter
CH56_3016	COG0577	efflux transmembrane transporter activity
CH56_3020	COG0006	proline dipeptidase activity
CH56_3021	COG0457	Tetratricopeptide repeat
CH56_3022	COG1649	PFAM Uncharacterised BCR, COG1649
CH56_3022	COG0726	polysaccharide deacetylase
CH56_3023	COG1215	transferase activity, transferring glycosyl groups
CH56_3024	COG3658	cytochrome
CH56_3026	COG3328	transposase activity
CH56_3027	COG3328	transposase activity
CH56_3028	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH56_3029	COG2350	Protein conserved in bacteria
CH56_3039	COG4608	Belongs to the ABC transporter superfamily
CH56_304	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH56_3040	COG0444	Belongs to the ABC transporter superfamily
CH56_3041	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH56_3042	COG0601	transmembrane transport
CH56_3044	COG2095	MarC family integral membrane protein
CH56_3045	COG1012	belongs to the aldehyde dehydrogenase family
CH56_3045	COG1454	alcohol dehydrogenase
CH56_3046	COG1435	thymidine kinase activity
CH56_3049	COG3328	transposase activity
CH56_3050	COG3328	transposase activity
CH56_307	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH56_3070	COG3328	transposase activity
CH56_308	COG1737	Transcriptional regulator
CH56_3089	COG0657	acetylesterase activity
CH56_3089	COG2755	lipolytic protein G-D-S-L family
CH56_3092	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH56_3092	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH56_3092	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH56_3092	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH56_3094	COG1285	pathogenesis
CH56_3095	COG3042	response to heat
CH56_3096	COG3187	Heat shock protein
CH56_3097	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH56_3098	COG2911	Protein conserved in bacteria
CH56_310	COG0560	Phosphoserine phosphatase
CH56_3100	COG3784	Protein of unknown function (DUF1318)
CH56_3101	COG0246	Mannitol dehydrogenase
CH56_3102	COG2390	Transcriptional regulator
CH56_3104	COG1643	Atp-dependent helicase
CH56_3105	COG1643	Atp-dependent helicase
CH56_3106	COG1643	Atp-dependent helicase
CH56_3109	COG3591	Belongs to the peptidase S1B family
CH56_311	COG0590	tRNA wobble adenosine to inosine editing
CH56_3111	COG3038	cytochrome b561
CH56_3116	COG0583	DNA-binding transcription factor activity
CH56_3118	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH56_3119	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH56_3120	COG0671	phosphoesterase, PA-phosphatase related
CH56_3121	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH56_3122	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH56_3125	COG0023	Translation Initiation Factor
CH56_3129	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH56_3130	COG2879	small protein
CH56_3131	COG1966	Carbon starvation protein
CH56_3133	COG2271	Major facilitator Superfamily
CH56_3134	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH56_3135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH56_3137	COG4659	FMN binding
CH56_3138	COG4658	electron transport chain
CH56_3139	COG2207	Transcriptional regulator
CH56_3139	COG3708	Transcriptional regulator
CH56_3146	COG1132	(ABC) transporter
CH56_3148	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH56_3149	COG2274	protein secretion by the type I secretion system
CH56_3153	COG1879	ABC-type sugar transport system periplasmic component
CH56_3155	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_3157	COG0673	inositol 2-dehydrogenase activity
CH56_3158	COG0385	Bile acid
CH56_3160	COG5339	Protein conserved in bacteria
CH56_3162	COG0114	fumarate hydratase activity
CH56_3164	COG1609	Transcriptional regulator
CH56_3166	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH56_317	COG1943	Transposase
CH56_3172	COG1943	Transposase
CH56_3176	COG0028	Belongs to the TPP enzyme family
CH56_3177	COG0028	Belongs to the TPP enzyme family
CH56_3178	COG0440	acetolactate synthase activity
CH56_3179	COG1011	Hydrolase
CH56_318	COG2205	protein histidine kinase activity
CH56_3182	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH56_3183	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH56_3184	COG0589	response to stress
CH56_3185	COG0589	response to stress
CH56_3186	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH56_3187	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH56_3189	COG0531	amino acid
CH56_319	COG3170	Tfp pilus assembly protein FimV
CH56_3191	COG0745	RESPONSE REGULATOR receiver
CH56_3192	COG2205	protein histidine kinase activity
CH56_3193	COG2205	protein histidine kinase activity
CH56_3194	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH56_3196	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH56_3199	COG0616	signal peptide processing
CH56_320	COG2204	response regulator
CH56_3200	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_3202	COG1187	pseudouridine synthase activity
CH56_3203	COG0009	L-threonylcarbamoyladenylate synthase
CH56_3206	COG0512	Glutamine amidotransferase of anthranilate synthase
CH56_3208	COG0134	indole-3-glycerol-phosphate synthase activity
CH56_3208	COG0135	phosphoribosylanthranilate isomerase activity
CH56_321	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH56_321	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH56_3215	COG3047	cAMP biosynthetic process
CH56_322	COG0347	Belongs to the P(II) protein family
CH56_3220	COG1607	acyl-coa hydrolase
CH56_3221	COG3328	transposase activity
CH56_3223	COG0745	RESPONSE REGULATOR receiver
CH56_3226	COG0788	formyltetrahydrofolate deformylase activity
CH56_3229	COG3328	transposase activity
CH56_323	COG2188	Transcriptional regulator
CH56_3230	COG0583	DNA-binding transcription factor activity
CH56_3231	COG0708	Exodeoxyribonuclease III
CH56_3232	COG0494	nUDIX hydrolase
CH56_3234	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH56_3235	COG0709	Synthesizes selenophosphate from selenide and ATP
CH56_3236	COG0778	Nitroreductase
CH56_3237	COG0616	signal peptide processing
CH56_3238	COG0252	asparaginase activity
CH56_3239	COG1335	isochorismatase
CH56_3240	COG3139	Protein of unknown function (DUF1315)
CH56_3244	COG3713	MltA-interacting MipA family protein
CH56_3245	COG2766	serine protein kinase
CH56_3248	COG0583	DNA-binding transcription factor activity
CH56_3250	COG2814	Major facilitator Superfamily
CH56_3252	COG2719	SpoVR family
CH56_3258	COG1104	cysteine desulfurase activity
CH56_3260	COG3328	transposase activity
CH56_3261	COG3328	transposase activity
CH56_3278	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH56_3279	COG4948	Mandelate Racemase Muconate Lactonizing
CH56_328	COG0805	protein transport
CH56_3280	COG2866	Carboxypeptidase
CH56_3281	COG4166	transmembrane transport
CH56_3285	COG0582	viral genome integration into host DNA
CH56_3287	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH56_3288	COG2951	lytic endotransglycosylase activity
CH56_3291	COG2894	cell division
CH56_3292	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH56_3293	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH56_3294	COG0318	PFAM AMP-dependent synthetase and ligase
CH56_3295	COG3065	identical protein binding
CH56_3297	COG1199	ATP-dependent helicase activity
CH56_3298	COG0251	oxidation-reduction process
CH56_33	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH56_330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH56_3301	COG0800	Aldolase
CH56_3303	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH56_3304	COG1737	Transcriptional regulator
CH56_3305	COG0469	pyruvate kinase activity
CH56_3306	COG1560	Kdo2-lipid A biosynthetic process
CH56_3307	COG0739	heme binding
CH56_3308	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH56_3310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH56_3315	COG0494	nUDIX hydrolase
CH56_3317	COG1801	Protein of unknown function DUF72
CH56_3318	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH56_3322	COG3102	Protein conserved in bacteria
CH56_3325	COG3328	transposase activity
CH56_3326	COG3328	transposase activity
CH56_3330	COG0728	peptidoglycan biosynthetic process
CH56_3331	COG0673	inositol 2-dehydrogenase activity
CH56_3332	COG0673	inositol 2-dehydrogenase activity
CH56_3333	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH56_3336	COG3381	protein complex oligomerization
CH56_3339	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH56_334	COG1322	Protein conserved in bacteria
CH56_3340	COG3833	ABC-type maltose transport systems, permease component
CH56_3344	COG0659	secondary active sulfate transmembrane transporter activity
CH56_3347	COG2912	Transglutaminase-like superfamily
CH56_3348	COG3094	Invasion gene expression up-regulator, SirB
CH56_3349	COG2890	protein-(glutamine-N5) methyltransferase activity
CH56_335	COG0586	Pfam SNARE associated Golgi protein
CH56_3354	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH56_3357	COG0012	GTP binding
CH56_336	COG1966	Carbon starvation protein
CH56_3369	COG5002	protein histidine kinase activity
CH56_3378	COG0500	methyltransferase
CH56_338	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CH56_3383	COG3328	transposase activity
CH56_339	COG0412	Dienelactone hydrolase
CH56_3393	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH56_3394	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH56_3395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH56_3398	COG0402	S-adenosylhomocysteine deaminase activity
CH56_3410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH56_3411	COG3850	Histidine kinase
CH56_3412	COG0387	Pfam Sodium calcium exchanger
CH56_3413	COG1702	phosphate starvation-inducible protein PhoH
CH56_3414	COG1702	phosphate starvation-inducible protein PhoH
CH56_342	COG0583	DNA-binding transcription factor activity
CH56_3421	COG3106	COG3106 Predicted ATPase
CH56_3423	COG1983	PspC domain protein
CH56_3425	COG1842	Phage shock protein A
CH56_3426	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH56_3427	COG1943	Transposase
CH56_3428	COG4166	transmembrane transport
CH56_3429	COG4168	peptide transport system, permease
CH56_343	COG0679	Auxin Efflux Carrier
CH56_3430	COG4171	peptide transport system, permease
CH56_3432	COG4172	Belongs to the ABC transporter superfamily
CH56_3433	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH56_3433	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH56_3435	COG3104	oligopeptide transport
CH56_3438	COG3328	transposase activity
CH56_3439	COG0625	glutathione transferase activity
CH56_344	COG0584	glycerophosphoryl diester phosphodiesterase
CH56_3444	COG3895	Periplasmic Protein
CH56_3446	COG3133	Outer membrane lipoprotein
CH56_3449	COG4989	oxidoreductase activity
CH56_3450	COG3313	Fe-S protein
CH56_3451	COG2194	sulfuric ester hydrolase activity
CH56_3452	COG1309	transcriptional regulator
CH56_3453	COG1902	pentaerythritol trinitrate reductase activity
CH56_3455	COG0346	lactoylglutathione lyase activity
CH56_3456	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH56_3457	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH56_3459	COG0791	NLP P60 protein
CH56_3460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH56_3463	COG0583	DNA-binding transcription factor activity
CH56_3464	COG2814	Major facilitator Superfamily
CH56_3465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH56_3467	COG0307	riboflavin synthase, alpha
CH56_3472	COG4238	major outer membrane lipoprotein
CH56_3474	COG3328	transposase activity
CH56_3477	COG1376	ErfK ybiS ycfS ynhG family protein
CH56_3477	COG1388	LysM domain
CH56_3480	COG0719	Fe-S assembly protein
CH56_3481	COG0396	ATPase activity
CH56_3482	COG0719	Fe-S assembly protein
CH56_3483	COG0316	Belongs to the HesB IscA family
CH56_3484	COG2050	protein possibly involved in aromatic compounds catabolism
CH56_3485	COG0247	lactate metabolic process
CH56_3485	COG0277	FAD linked oxidase domain protein
CH56_3486	COG0628	permease
CH56_3488	COG0574	Belongs to the PEP-utilizing enzyme family
CH56_3488	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH56_3495	COG0791	NLP P60 protein
CH56_35	COG2805	Type II/IV secretion system protein
CH56_3503	COG1943	Transposase
CH56_3504	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CH56_3505	COG0386	Belongs to the glutathione peroxidase family
CH56_3509	COG0776	regulation of translation
CH56_3510	COG0072	phenylalanine-tRNA ligase activity
CH56_3510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH56_3511	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH56_3516	COG4249	Peptidase C14 caspase catalytic subunit p20
CH56_3520	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH56_3521	COG1121	(ABC) transporter
CH56_3522	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH56_3523	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH56_3526	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH56_3527	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH56_3528	COG3328	transposase activity
CH56_3529	COG1917	Cupin 2, conserved barrel domain protein
CH56_3531	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_3533	COG1175	transmembrane transport
CH56_3534	COG0395	ABC-type sugar transport system, permease component
CH56_3535	COG3842	ATPase activity
CH56_3536	COG1653	transport
CH56_3537	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH56_3538	COG1988	membrane-bound metal-dependent
CH56_3540	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH56_3542	COG0823	Involved in the tonB-independent uptake of proteins
CH56_3543	COG2814	Major facilitator Superfamily
CH56_3544	COG3121	Chaperone
CH56_3548	COG3121	Chaperone
CH56_3549	COG3539	Fimbrial protein
CH56_3553	COG0793	Belongs to the peptidase S41A family
CH56_3555	COG1956	GAF domain-containing protein
CH56_3556	COG2995	paraquat-inducible protein a
CH56_3557	COG3008	intermembrane lipid transfer
CH56_3561	COG3121	Chaperone
CH56_357	COG0410	ABC transporter
CH56_3570	COG1953	Uracil, thiamine, allantoin
CH56_3572	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH56_3574	COG2226	methyltransferase
CH56_3576	COG1388	LysM domain
CH56_3576	COG0741	lytic transglycosylase activity
CH56_3579	COG0656	L-ascorbic acid biosynthetic process
CH56_358	COG0411	ABC transporter
CH56_3580	COG3328	transposase activity
CH56_3581	COG3328	transposase activity
CH56_3583	COG3328	transposase activity
CH56_3584	COG3328	transposase activity
CH56_3585	COG3188	usher protein
CH56_3586	COG3121	Chaperone
CH56_359	COG0411	ABC transporter
CH56_3598	COG2951	lytic endotransglycosylase activity
CH56_360	COG4177	L-phenylalanine transmembrane transporter activity
CH56_3605	COG0243	molybdopterin cofactor binding
CH56_3606	COG0437	4 iron, 4 sulfur cluster binding
CH56_3607	COG3302	dmso reductase anchor subunit
CH56_3608	COG3381	protein complex oligomerization
CH56_361	COG4177	L-phenylalanine transmembrane transporter activity
CH56_3614	COG3038	cytochrome b561
CH56_3615	COG0436	Aminotransferase
CH56_362	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH56_3620	COG0667	Aldo Keto reductase
CH56_3624	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH56_3625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH56_363	COG0683	leucine binding
CH56_3633	COG3530	Putative quorum-sensing-regulated virulence factor
CH56_3636	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH56_3637	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH56_3638	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH56_3639	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_3641	COG2190	(PTS) system
CH56_3642	COG1943	Transposase
CH56_3644	COG2205	protein histidine kinase activity
CH56_3645	COG0745	RESPONSE REGULATOR receiver
CH56_3646	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH56_3649	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH56_3651	COG0006	proline dipeptidase activity
CH56_3653	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH56_3656	COG5002	protein histidine kinase activity
CH56_3656	COG3850	Histidine kinase
CH56_3657	COG0745	RESPONSE REGULATOR receiver
CH56_3660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH56_3661	COG4208	sulfate ABC transporter
CH56_3662	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH56_3663	COG4150	thiosulfate binding
CH56_3665	COG1737	Transcriptional regulator
CH56_3666	COG2731	YhcH YjgK YiaL family protein
CH56_3668	COG4886	Leucine-rich repeat (LRR) protein
CH56_3670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH56_3671	COG2837	iron assimilation
CH56_3673	COG3111	PFAM Bacterial OB fold (BOF) protein
CH56_3682	COG3005	denitrification pathway
CH56_3683	COG3043	anaerobic respiration
CH56_3685	COG3062	negative regulation of establishment of protein localization
CH56_3686	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH56_3686	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH56_3687	COG2197	response regulator
CH56_3689	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH56_37	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH56_3700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH56_3701	COG0250	Participates in transcription elongation, termination and antitermination
CH56_3709	COG1943	Transposase
CH56_3710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH56_3711	COG0537	adenosine 5'-monophosphoramidase activity
CH56_3712	COG5633	Lipoprotein
CH56_3715	COG1472	Belongs to the glycosyl hydrolase 3 family
CH56_3717	COG1252	NADH dehydrogenase
CH56_3719	COG3328	transposase activity
CH56_372	COG0049	tRNA binding
CH56_3720	COG2271	Major facilitator Superfamily
CH56_3721	COG0835	chemotaxis
CH56_3722	COG0643	Histidine kinase
CH56_3722	COG2198	Histidine kinase
CH56_3723	COG1360	Flagellar Motor Protein
CH56_3728	COG1285	pathogenesis
CH56_3729	COG0840	transmembrane signaling receptor activity
CH56_373	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH56_3730	COG0840	transmembrane signaling receptor activity
CH56_3732	COG1278	Cold shock
CH56_3734	COG0604	alcohol dehydrogenase
CH56_3734	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_3734	COG3321	synthase
CH56_3736	COG1522	sequence-specific DNA binding
CH56_3741	COG1733	regulation of RNA biosynthetic process
CH56_3742	COG0702	epimerase
CH56_3743	COG0840	transmembrane signaling receptor activity
CH56_3746	COG0538	isocitrate dehydrogenase activity
CH56_3747	COG1187	pseudouridine synthase activity
CH56_3751	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH56_3753	COG0745	RESPONSE REGULATOR receiver
CH56_3755	COG2850	peptidyl-arginine hydroxylation
CH56_3757	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH56_3759	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH56_3761	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH56_3762	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH56_3763	COG3134	Outer membrane lipoprotein
CH56_3764	COG3328	transposase activity
CH56_3765	COG3188	usher protein
CH56_377	COG2964	Protein conserved in bacteria
CH56_3776	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH56_3777	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH56_3778	COG1309	transcriptional regulator
CH56_3779	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH56_378	COG0545	Peptidyl-prolyl cis-trans isomerase
CH56_3780	COG3264	Mechanosensitive ion channel
CH56_3780	COG1196	nuclear chromosome segregation
CH56_3783	COG2832	Protein of unknown function (DUF454)
CH56_3785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH56_3791	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH56_3791	COG0543	2 iron, 2 sulfur cluster binding
CH56_3796	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH56_3798	COG3328	transposase activity
CH56_3799	COG3328	transposase activity
CH56_380	COG1047	Peptidyl-prolyl cis-trans
CH56_3800	COG3137	Salt-induced outer membrane protein
CH56_3801	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH56_3802	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH56_3807	COG0494	nUDIX hydrolase
CH56_381	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH56_3812	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH56_3813	COG0849	cell division
CH56_3814	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH56_3818	COG0772	Belongs to the SEDS family
CH56_3821	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH56_3822	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH56_3823	COG0768	penicillin binding
CH56_3824	COG3116	cell division
CH56_3828	COG1609	Transcriptional regulator
CH56_3829	COG1943	Transposase
CH56_3831	COG0028	Belongs to the TPP enzyme family
CH56_3832	COG1022	Amp-dependent synthetase and ligase
CH56_3835	COG1943	Transposase
CH56_3837	COG0473	3-isopropylmalate dehydrogenase activity
CH56_384	COG0488	(ABC) transporter
CH56_3840	COG2814	Major facilitator Superfamily
CH56_3843	COG4143	(ABC) transporter
CH56_3844	COG1178	ABC-type Fe3 transport system permease component
CH56_3846	COG0586	Pfam SNARE associated Golgi protein
CH56_3847	COG0417	DNA replication proofreading
CH56_385	COG1216	Glycosyl transferase, family 2
CH56_3852	COG3047	cAMP biosynthetic process
CH56_3852	COG2885	chlorophyll binding
CH56_3860	COG3501	Rhs element vgr protein
CH56_3865	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_3867	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH56_3868	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH56_3869	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_387	COG2175	clavaminate synthase activity
CH56_3870	COG3425	synthase
CH56_3872	COG1024	Enoyl-CoA hydratase
CH56_3873	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_3875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH56_3876	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH56_388	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH56_3899	COG0488	(ABC) transporter
CH56_390	COG4521	taurine ABC transporter
CH56_3902	COG0303	'Molybdopterin
CH56_3904	COG1136	(ABC) transporter
CH56_3908	COG3328	transposase activity
CH56_3912	COG0583	DNA-binding transcription factor activity
CH56_3913	COG0477	Major facilitator Superfamily
CH56_3916	COG2311	Membrane
CH56_3919	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH56_392	COG0429	hydrolase of the alpha beta-hydrolase fold
CH56_3921	COG2949	membrane
CH56_3925	COG1346	cytolysis
CH56_3927	COG2814	Major facilitator Superfamily
CH56_3931	COG1943	Transposase
CH56_3933	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH56_3937	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH56_3938	COG3695	enzyme binding
CH56_3939	COG1946	Acyl-CoA thioesterase
CH56_394	COG3954	Phosphoribulokinase
CH56_3940	COG0004	ammonium transporteR
CH56_3941	COG0347	Belongs to the P(II) protein family
CH56_3942	COG1132	(ABC) transporter
CH56_3943	COG1132	(ABC) transporter
CH56_3944	COG1522	sequence-specific DNA binding
CH56_3947	COG4533	DNA binding
CH56_3949	COG0824	Thioesterase
CH56_3950	COG1555	photosystem II stabilization
CH56_3951	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH56_3953	COG0776	regulation of translation
CH56_3954	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH56_3959	COG0271	Belongs to the BolA IbaG family
CH56_396	COG1765	OsmC-like protein
CH56_3960	COG3056	Lipoprotein
CH56_3961	COG2223	nitrite transmembrane transporter activity
CH56_3963	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH56_3964	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH56_3965	COG1845	cytochrome c oxidase, subunit III
CH56_3966	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH56_3968	COG1943	Transposase
CH56_3969	COG2814	Major facilitator Superfamily
CH56_3971	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH56_3972	COG0693	protein deglycase activity
CH56_3975	COG0142	geranyltranstransferase activity
CH56_3978	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH56_398	COG1289	transmembrane transporter activity
CH56_3980	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_3981	COG1129	ABC transporter
CH56_3982	COG1129	ABC transporter
CH56_3983	COG0371	Dehydrogenase
CH56_3985	COG0531	amino acid
CH56_3986	COG2925	Exonuclease
CH56_3989	COG3328	transposase activity
CH56_3992	COG0351	phosphomethylpyrimidine kinase
CH56_3998	COG3422	double-strand break repair
CH56_3999	COG0745	RESPONSE REGULATOR receiver
CH56_40	COG0189	ligase activity
CH56_4000	COG2205	protein histidine kinase activity
CH56_4005	COG3842	ATPase activity
CH56_4007	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH56_4009	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH56_401	COG0433	COG0433 Predicted ATPase
CH56_4010	COG1177	transmembrane transport
CH56_4011	COG0443	Heat shock 70 kDa protein
CH56_4012	COG2239	Acts as a magnesium transporter
CH56_4013	COG0248	Ppx GppA phosphatase
CH56_4014	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH56_4016	COG0581	inorganic phosphate transmembrane transporter activity
CH56_402	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH56_4020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH56_4021	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH56_4024	COG2801	Transposase and inactivated derivatives
CH56_4026	COG1943	Transposase
CH56_4028	COG1393	Belongs to the ArsC family
CH56_4029	COG4783	chaperone-mediated protein folding
CH56_403	COG1486	melibiose metabolic process
CH56_4030	COG0628	permease
CH56_4033	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH56_4034	COG2716	regulation of RNA biosynthetic process
CH56_4036	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH56_4039	COG2321	neutral zinc metallopeptidase
CH56_4043	COG1876	peptidase activity
CH56_4045	COG1393	Belongs to the ArsC family
CH56_4047	COG1840	ABC-type Fe3 transport system, periplasmic component
CH56_4048	COG1175	transmembrane transport
CH56_4049	COG3842	ATPase activity
CH56_4050	COG3119	arylsulfatase activity
CH56_4051	COG0641	radical SAM
CH56_4052	COG1988	membrane-bound metal-dependent
CH56_4057	COG1611	Belongs to the LOG family
CH56_4064	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH56_4064	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH56_4067	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH56_4068	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH56_407	COG0402	S-adenosylhomocysteine deaminase activity
CH56_4072	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH56_4074	COG0131	Imidazoleglycerol-phosphate dehydratase
CH56_4074	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH56_4075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CH56_4079	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH56_4079	COG0140	phosphoribosyl-ATP diphosphatase activity
CH56_408	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH56_4081	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH56_4082	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH56_4086	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH56_4087	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH56_4088	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH56_4089	COG1120	ATPase activity
CH56_409	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH56_4092	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH56_4093	COG0076	glutamate decarboxylase activity
CH56_4094	COG4114	ferric iron reductase
CH56_4095	COG1253	flavin adenine dinucleotide binding
CH56_4096	COG2982	Protein involved in outer membrane biogenesis
CH56_4099	COG0489	protein tyrosine kinase activity
CH56_41	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH56_410	COG2146	nitrite reductase [NAD(P)H] activity
CH56_4102	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH56_4102	COG2885	chlorophyll binding
CH56_4104	COG3070	regulator of competence-specific genes
CH56_4105	COG1289	transmembrane transporter activity
CH56_4106	COG3304	Inner membrane component domain
CH56_4107	COG0210	DNA helicase
CH56_4110	COG1832	CoA-binding protein
CH56_4114	COG2920	part of a sulfur-relay system
CH56_4125	COG2363	Small membrane protein
CH56_4126	COG0583	DNA-binding transcription factor activity
CH56_4128	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH56_4129	COG2166	iron-sulfur cluster assembly
CH56_413	COG0180	Tryptophanyl-tRNA synthetase
CH56_4130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH56_4131	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH56_4134	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH56_4136	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH56_4137	COG1074	ATP-dependent DNA helicase activity
CH56_4139	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH56_414	COG0546	phosphoglycolate phosphatase activity
CH56_415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH56_4150	COG0667	Aldo Keto reductase
CH56_4156	COG0019	diaminopimelate decarboxylase activity
CH56_4157	COG1609	Transcriptional regulator
CH56_4158	COG2814	Major facilitator Superfamily
CH56_4159	COG0583	DNA-binding transcription factor activity
CH56_4160	COG0583	DNA-binding transcription factor activity
CH56_4162	COG0840	transmembrane signaling receptor activity
CH56_4180	COG0288	reversible hydration of carbon dioxide
CH56_4187	COG0366	Alpha amylase catalytic
CH56_4189	COG1114	Component of the transport system for branched-chain amino acids
CH56_4191	COG5002	protein histidine kinase activity
CH56_4192	COG0745	RESPONSE REGULATOR receiver
CH56_4193	COG0420	3'-5' exonuclease activity
CH56_4194	COG0419	ATPase involved in DNA repair
CH56_4195	COG1940	carbohydrate kinase activity
CH56_42	COG2356	endonuclease I
CH56_420	COG4796	Type ii and iii secretion system protein
CH56_4200	COG2226	methyltransferase
CH56_4208	COG3941	tape measure
CH56_4215	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH56_4215	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH56_4216	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH56_4232	COG3328	transposase activity
CH56_4234	COG3344	reverse transcriptase
CH56_4236	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH56_425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH56_4253	COG1475	DNA binding
CH56_4256	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH56_4258	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH56_4259	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH56_426	COG0494	nUDIX hydrolase
CH56_4266	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH56_4277	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH56_4288	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH56_4289	COG1475	DNA binding
CH56_429	COG1011	Hydrolase
CH56_4290	COG1475	DNA binding
CH56_430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH56_4308	COG2801	Transposase and inactivated derivatives
CH56_4326	COG0515	serine threonine protein kinase
CH56_4328	COG2801	Transposase and inactivated derivatives
CH56_4331	COG2801	Transposase and inactivated derivatives
CH56_4332	COG2963	transposase activity
CH56_4333	COG5599	Phosphatase
CH56_4334	COG1317	bacterial-type flagellum organization
CH56_4336	COG4669	(LipO)protein
CH56_434	COG0745	RESPONSE REGULATOR receiver
CH56_4345	COG2207	Transcriptional regulator
CH56_4347	COG4792	protein secretion
CH56_4348	COG4791	protein targeting
CH56_4349	COG4794	Type iii secretion
CH56_435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH56_4350	COG4790	Type iii secretion
CH56_4351	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH56_436	COG2183	response to ionizing radiation
CH56_4360	COG4789	Type iii secretion
CH56_4364	COG0457	Tetratricopeptide repeat
CH56_4368	COG4886	Leucine-rich repeat (LRR) protein
CH56_4368	COG4886	Leucine-rich repeat (LRR) protein
CH56_437	COG1918	ferrous iron import across plasma membrane
CH56_4373	COG3177	Filamentation induced by cAMP protein fic
CH56_4377	COG2801	Transposase and inactivated derivatives
CH56_4379	COG1192	Involved in chromosome partitioning
CH56_4380	COG1475	DNA binding
CH56_4382	COG3609	addiction module antidote protein, CC2985 family
CH56_4384	COG5599	Phosphatase
CH56_4386	COG2801	Transposase and inactivated derivatives
CH56_4391	COG2801	Transposase and inactivated derivatives
CH56_4397	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CH56_444	COG1640	4-alpha-glucanotransferase
CH56_445	COG0058	SHG alpha-glucan phosphorylase activity
CH56_446	COG0058	SHG alpha-glucan phosphorylase activity
CH56_451	COG1349	DNA-binding transcription factor activity
CH56_453	COG2801	Transposase and inactivated derivatives
CH56_46	COG1166	arginine decarboxylase activity
CH56_460	COG3276	selenocysteine insertion sequence binding
CH56_461	COG3276	selenocysteine insertion sequence binding
CH56_464	COG2864	formate dehydrogenase
CH56_465	COG0437	4 iron, 4 sulfur cluster binding
CH56_466	COG3383	formate dehydrogenase (NAD+) activity
CH56_466	COG0243	molybdopterin cofactor binding
CH56_467	COG3383	formate dehydrogenase (NAD+) activity
CH56_467	COG0243	molybdopterin cofactor binding
CH56_469	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH56_476	COG3722	fumarate hydratase activity
CH56_478	COG2213	PTS system mannitol-specific
CH56_478	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_48	COG0501	Belongs to the peptidase M48B family
CH56_483	COG2818	Glycosylase
CH56_485	COG2885	chlorophyll binding
CH56_488	COG0366	Alpha amylase catalytic
CH56_49	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH56_490	COG3977	Valine--pyruvate aminotransferase
CH56_494	COG5645	(Lipo)protein
CH56_495	COG0823	Involved in the tonB-independent uptake of proteins
CH56_496	COG0823	Involved in the tonB-independent uptake of proteins
CH56_497	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH56_498	COG2423	ornithine cyclodeaminase activity
CH56_5	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH56_50	COG1943	Transposase
CH56_503	COG2801	Transposase and inactivated derivatives
CH56_505	COG0527	aspartate kinase activity
CH56_505	COG0460	homoserine dehydrogenase
CH56_506	COG0626	cystathionine gamma-synthase activity
CH56_508	COG4682	membrane
CH56_51	COG1263	PTS System
CH56_51	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH56_511	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH56_513	COG1609	Transcriptional regulator
CH56_517	COG0191	fructose-bisphosphate aldolase activity
CH56_522	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH56_523	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH56_524	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH56_527	COG0006	proline dipeptidase activity
CH56_528	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH56_529	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH56_535	COG5295	Hep Hag repeat protein
CH56_538	COG1272	protein, Hemolysin III
CH56_54	COG1943	Transposase
CH56_541	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH56_542	COG0745	RESPONSE REGULATOR receiver
CH56_543	COG2205	protein histidine kinase activity
CH56_544	COG4452	Inner membrane protein CreD
CH56_545	COG0716	FMN binding
CH56_546	COG4974	Belongs to the 'phage' integrase family
CH56_547	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH56_548	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH56_552	COG0582	viral genome integration into host DNA
CH56_557	COG2944	sequence-specific DNA binding
CH56_56	COG2271	Major facilitator Superfamily
CH56_574	COG1695	Transcriptional regulator
CH56_575	COG0791	NLP P60 protein
CH56_576	COG1879	ABC-type sugar transport system periplasmic component
CH56_577	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_578	COG1129	ABC transporter
CH56_580	COG2182	Extracellular solute-binding protein
CH56_581	COG1175	transmembrane transport
CH56_582	COG3833	ABC-type maltose transport systems, permease component
CH56_583	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH56_584	COG1874	Beta-galactosidase
CH56_585	COG1874	Beta-galactosidase
CH56_587	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH56_592	COG1629	transport
CH56_596	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH56_60	COG0191	fructose-bisphosphate aldolase activity
CH56_601	COG2801	Transposase and inactivated derivatives
CH56_612	COG1175	transmembrane transport
CH56_613	COG3833	ABC-type maltose transport systems, permease component
CH56_616	COG0527	aspartate kinase activity
CH56_62	COG3119	arylsulfatase activity
CH56_621	COG1414	Transcriptional regulator
CH56_63	COG0641	radical SAM
CH56_646	COG1301	dicarboxylic acid transport
CH56_648	COG3162	membrane
CH56_65	COG1028	Short-chain dehydrogenase reductase Sdr
CH56_653	COG3061	Opacity-associated protein A
CH56_654	COG0545	Peptidyl-prolyl cis-trans isomerase
CH56_656	COG0737	Belongs to the 5'-nucleotidase family
CH56_658	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH56_660	COG1253	flavin adenine dinucleotide binding
CH56_662	COG0729	surface antigen
CH56_663	COG2911	Protein conserved in bacteria
CH56_664	COG2105	PFAM AIG2 family protein
CH56_665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH56_667	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH56_67	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH56_671	COG3423	Transcriptional regulator
CH56_673	COG0142	geranyltranstransferase activity
CH56_676	COG0697	spore germination
CH56_679	COG0642	Histidine kinase
CH56_68	COG3716	PTS system mannose fructose sorbose family IID component
CH56_680	COG0642	Histidine kinase
CH56_681	COG0745	RESPONSE REGULATOR receiver
CH56_682	COG2027	D-alanyl-D-alanine carboxypeptidase
CH56_683	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH56_684	COG1534	Rna-binding protein
CH56_686	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH56_687	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH56_689	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH56_69	COG3715	PTS system
CH56_693	COG0195	Participates in both transcription termination and antitermination
CH56_699	COG2801	Transposase and inactivated derivatives
CH56_70	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH56_702	COG0513	Belongs to the DEAD box helicase family
CH56_705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH56_708	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH56_71	COG2222	sugar isomerase
CH56_713	COG3153	acetyltransferase
CH56_717	COG1653	transport
CH56_719	COG0395	ABC-type sugar transport system, permease component
CH56_720	COG3842	ATPase activity
CH56_723	COG0702	epimerase
CH56_724	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH56_725	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH56_726	COG3454	Phosphonate metabolism
CH56_727	COG4778	phosphonate C-P lyase system protein PhnL
CH56_728	COG4107	phosphonate C-P lyase system protein PhnK
CH56_729	COG3627	carbon phosphorus lyase activity
CH56_73	COG1349	DNA-binding transcription factor activity
CH56_730	COG3626	phosphonate metabolism
CH56_731	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH56_732	COG3624	Phosphonate C-P lyase system protein PhnG
CH56_733	COG2188	Transcriptional regulator
CH56_737	COG4608	Belongs to the ABC transporter superfamily
CH56_738	COG0444	Belongs to the ABC transporter superfamily
CH56_739	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH56_74	COG3119	arylsulfatase activity
CH56_740	COG0601	transmembrane transport
CH56_743	COG2731	YhcH YjgK YiaL family protein
CH56_744	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CH56_745	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH56_747	COG0525	valine-tRNA ligase activity
CH56_748	COG2927	DNA polymerase III (CHI subunit)
CH56_750	COG0795	lipopolysaccharide-transporting ATPase activity
CH56_751	COG0795	lipopolysaccharide-transporting ATPase activity
CH56_753	COG0582	viral genome integration into host DNA
CH56_76	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH56_760	COG0747	negative chemotaxis
CH56_761	COG0601	transmembrane transport
CH56_762	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH56_763	COG0444	Belongs to the ABC transporter superfamily
CH56_764	COG4608	Belongs to the ABC transporter superfamily
CH56_765	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH56_766	COG2200	EAL domain
CH56_766	COG2199	diguanylate cyclase activity
CH56_767	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH56_77	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH56_772	COG0612	Peptidase, M16
CH56_773	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH56_774	COG1942	4-Oxalocrotonate Tautomerase
CH56_775	COG2200	EAL domain
CH56_776	COG2982	Protein involved in outer membrane biogenesis
CH56_777	COG2134	cdp-diacylglycerol pyrophosphatase
CH56_778	COG1295	ribonuclease BN
CH56_78	COG1862	Preprotein translocase
CH56_783	COG1929	Belongs to the glycerate kinase type-1 family
CH56_784	COG2610	gluconate transmembrane transporter activity
CH56_785	COG3835	regulator
CH56_786	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH56_787	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH56_788	COG0339	signal peptide processing
CH56_792	COG0589	response to stress
CH56_793	COG3328	transposase activity
CH56_796	COG0306	phosphate transporter
CH56_797	COG2081	HI0933 family
CH56_80	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CH56_800	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH56_801	COG1879	ABC-type sugar transport system periplasmic component
CH56_804	COG0191	fructose-bisphosphate aldolase activity
CH56_808	COG1741	Belongs to the pirin family
CH56_809	COG1609	Transcriptional regulator
CH56_81	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CH56_810	COG2610	gluconate transmembrane transporter activity
CH56_811	COG3265	gluconokinase activity
CH56_815	COG2095	MarC family integral membrane protein
CH56_816	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH56_82	COG0450	alkyl hydroperoxide reductase
CH56_822	COG3275	phosphorelay sensor kinase activity
CH56_825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CH56_827	COG0058	SHG alpha-glucan phosphorylase activity
CH56_828	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH56_829	COG3328	transposase activity
CH56_83	COG1943	Transposase
CH56_833	COG2831	hemolysin activation secretion protein
CH56_837	COG2271	Major facilitator Superfamily
CH56_838	COG3851	Histidine kinase
CH56_839	COG2197	response regulator
CH56_840	COG2194	sulfuric ester hydrolase activity
CH56_843	COG2986	histidine ammonia-lyase
CH56_846	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH56_849	COG4607	ABC-type enterochelin transport system periplasmic component
CH56_851	COG4605	iron ion homeostasis
CH56_853	COG4604	ABC transporter, ATP-binding protein
CH56_860	COG0582	viral genome integration into host DNA
CH56_862	COG2207	Transcriptional regulator
CH56_862	COG1609	Transcriptional regulator
CH56_863	COG4214	carbohydrate transport
CH56_866	COG4213	ABC transporter substrate-binding protein
CH56_867	COG4213	ABC transporter substrate-binding protein
CH56_869	COG1070	Carbohydrate kinase
CH56_87	COG0366	Alpha amylase catalytic
CH56_871	COG3121	Chaperone
CH56_872	COG3188	usher protein
CH56_873	COG3188	usher protein
CH56_874	COG3188	usher protein
CH56_876	COG3274	enterobacterial common antigen metabolic process
CH56_879	COG2801	Transposase and inactivated derivatives
CH56_880	COG0561	phosphatase activity
CH56_881	COG0187	DNA topoisomerase II activity
CH56_882	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH56_883	COG0592	DNA-directed DNA polymerase activity
CH56_886	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH56_889	COG0706	membrane insertase activity
CH56_894	COG2252	PERMEase
CH56_895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH56_896	COG0765	amino acid transport
CH56_897	COG0765	amino acid transport
CH56_898	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH56_9	COG1477	protein flavinylation
CH56_900	COG0704	Plays a role in the regulation of phosphate uptake
CH56_902	COG0581	inorganic phosphate transmembrane transporter activity
CH56_903	COG0573	inorganic phosphate transmembrane transporter activity
CH56_904	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH56_905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH56_915	COG3312	ion transport
CH56_918	COG0716	FMN binding
CH56_919	COG1522	sequence-specific DNA binding
CH56_92	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH56_925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH56_926	COG0477	Major facilitator Superfamily
CH56_928	COG2186	Transcriptional regulator
CH56_933	COG3328	transposase activity
CH56_934	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH56_936	COG3084	Protein conserved in bacteria
CH56_937	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH56_938	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH56_939	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH56_939	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH56_942	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH56_944	COG3852	Histidine kinase
CH56_946	COG0174	glutamine synthetase
CH56_948	COG1011	Hydrolase
CH56_949	COG1295	ribonuclease BN
CH56_952	COG0456	acetyltransferase
CH56_953	COG2982	Protein involved in outer membrane biogenesis
CH56_954	COG2233	PERMEase
CH56_955	COG0786	glutamate:sodium symporter activity
CH56_956	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH56_957	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH56_958	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH56_962	COG2860	membrane
CH56_963	COG1561	YicC-like family, N-terminal region
CH56_965	COG1943	Transposase
CH56_969	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH56_97	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH56_972	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH56_976	COG1519	Transferase
CH56_977	COG0859	PFAM glycosyl transferase family 9
CH56_978	COG0859	PFAM glycosyl transferase family 9
CH56_980	COG0156	8-amino-7-oxononanoate synthase activity
CH56_982	COG2861	carbohydrate metabolic process
CH56_983	COG2861	carbohydrate metabolic process
CH56_984	COG4942	peptidase
CH56_986	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH56_987	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH56_99	COG2011	ABC-type metal ion transport system permease component
CH56_990	COG1045	serine acetyltransferase
CH56_991	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH56_992	COG2169	Transcriptional regulator
CH56_992	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH56_995	COG2205	protein histidine kinase activity
CH56_996	COG0745	RESPONSE REGULATOR receiver
CH56_997	COG3678	ATP-independent chaperone mediated protein folding