locus-tag class description YPA_0001 ENOG4105QTB Flavodoxin YPA_0002 ENOG4108VVK transcriptional Regulator, AsnC YPA_0011 ENOG4108RVA ribokinase YPA_0013 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPA_0014 ENOG4107EJG GntR family transcriptional regulator YPA_0017 ENOG4107QP3 malate synthase g YPA_0018 ENOG4108I9X Isocitrate lyase YPA_0020 ENOG41069M3 Transcriptional regulator YPA_0021 ENOG4105C3R Methionine synthase YPA_0025 ENOG4105CFH Aspartokinase YPA_0028 ENOG4105EG2 ABC transporter, permease YPA_0029 ENOG4105D56 permease protein YPA_0030 ENOG4107FKK extracellular solute-binding protein family 1 YPA_0034 ENOG4107W52 maltose operon periplasmic protein YPA_0036 ENOG4108WC9 type VI secretion system effector, hcp1 family YPA_0041 ENOG4105DQ6 Transposase YPA_0047 ENOG4105CHV Transcription elongation factor NusA YPA_0051 ENOG4105EEI dihydropteroate synthase YPA_0052 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) YPA_0054 ENOG4105HBR Rna-binding protein YPA_0055 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) YPA_0056 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase YPA_0060 ENOG4105QYV Membrane YPA_0063 ENOG4105EAH synthase YPA_0065 ENOG4105HVQ Regulatory factor of maltose metabolism YPA_0069 ENOG4105DFU Cell wall formation (By similarity) YPA_0071 ENOG4105F0N pyrophosphate phospho-hydrolase YPA_0072 ENOG4108ZHD aig2 family YPA_0073 ENOG4105MA0 exported protein YPA_0074 ENOG4105CFU surface antigen YPA_0076 ENOG4105C37 (CBS) domain YPA_0077 ENOG41061GZ Protein of unknown function (DUF1107) YPA_0078 ENOG4108UUE Transcriptional regulator YPA_0079 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase YPA_0080 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic YPA_0082 ENOG4108V1T peptidylprolyl cis-trans isomerase YPA_0083 ENOG4105FHY Opacity-associated protein A YPA_0085 ENOG4108RS6 transposase YPA_0087 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) YPA_0089 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) YPA_0091 ENOG4108MXZ Esterase YPA_0097 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase YPA_0100 ENOG4105X58 receptor YPA_0103 ENOG4107QZV Type I secretion membrane fusion protein YPA_0104 ENOG4105YHG TonB family YPA_0105 ENOG4107QN2 dihydrolipoyl dehydrogenase YPA_0106 ENOG4105EHV domain protein YPA_0107 ENOG4105C5Q Transcriptional regulator YPA_0110 ENOG4108Y73 Membrane YPA_0114 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator YPA_0115 ENOG4105C2J ABC transporter YPA_0116 ENOG4107R9N ABC transporter YPA_0117 ENOG41062B0 ABC transporter, permease YPA_0119 ENOG4108WFC UPF0438 protein yifE YPA_0120 ENOG4105C0P Mg chelatase subunit ChlI YPA_0122 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit YPA_0123 ENOG4105CM2 brancheD-chain amino acid aminotransferase YPA_0125 ENOG4105C7B Threonine dehydratase YPA_0131 ENOG4105EMY transcriptional regulator YPA_0138 ENOG4108VEV chaperone YPA_0140 ENOG4105CW0 outer membrane usher protein YPA_0141 ENOG4105GQR Chaperone YPA_0145 ENOG4105KQ5 peptidylprolyl cis-trans isomerase YPA_0146 ENOG4105C4R Atp-dependent dna helicase YPA_0150 ENOG4105K63 Thioredoxin YPA_0152 ENOG4105ESV Glycosyl transferase, family 4 YPA_0153 ENOG4105SFE lipopolysaccharide biosynthesis protein YPA_0154 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase YPA_0155 ENOG4108IJ1 Dehydrogenase YPA_0156 ENOG4105C1B dTDP-glucose 4-6-dehydratase YPA_0157 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) YPA_0158 ENOG4108WJ1 acetyltransferase YPA_0159 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase YPA_0160 ENOG4105EGZ biosynthesis protein YPA_0164 ENOG4105C85 amino acid YPA_0168 ENOG4108RS6 transposase YPA_0169 ENOG410601J HemY protein YPA_0170 ENOG4105ECF c-methyltransferase YPA_0171 ENOG41076E6 Uroporphyrinogen-III Synthase YPA_0174 ENOG4107T0K Adenylate cyclase YPA_0176 ENOG4105S7Z (LipO)protein YPA_0178 ENOG4105CT0 Protein of unknown function, DUF484 YPA_0179 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPA_0180 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant YPA_0181 ENOG4105C4R Atp-dependent dna helicase YPA_0183 ENOG4105EQN UPF0261 protein YPA_0185 ENOG4107QUT magnesium and cobalt transport protein CorA YPA_0186 ENOG4105FR1 rard protein YPA_0187 ENOG4108VUY thioesterase Superfamily protein YPA_0188 ENOG4105HDD phospholipase YPA_0189 ENOG4105C9U ATP-dependent DNA helicase RecQ YPA_0190 ENOG4105CCF Lysine exporter protein (Lyse ygga) YPA_0192 ENOG4108EUD Lysophospholipase YPA_0193 ENOG4105DQF Hydrolase YPA_0195 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase YPA_0196 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A YPA_0198 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) YPA_0199 ENOG4108W1V Lipoprotein YPA_0200 ENOG4105EX9 Membrane YPA_0203 ENOG4107FS9 Membrane YPA_0206 ENOG4105MG3 Membrane YPA_0207 ENOG4106H78 methyltransferase YPA_0208 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) YPA_0208 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) YPA_0209 ENOG4105CAK Cell division ATP-binding protein ftsE YPA_0210 ENOG4105CRP Part of the ABC transporter FtsEX involved in YPA_0212 ENOG4108RS6 transposase YPA_0213 ENOG4105U59 -acetyltransferase YPA_0214 ENOG4105CP9 extracellular ligand-binding receptor YPA_0217 ENOG4105C32 Amino acid ABC transporter (Permease) YPA_0218 ENOG4105CF8 branched-chain amino acid ABC transporter, permease YPA_0219 ENOG4105C0Z ABC transporter YPA_0220 ENOG4108IV0 ABC, transporter YPA_0232 ENOG4107T6V glycerophosphoryl diester phosphodiesterase YPA_0233 ENOG4105RK9 auxin efflux carrier YPA_0234 ENOG4105EMK carboxylate amino acid amine transporter YPA_0235 ENOG4105DZ2 Transcriptional regulator YPA_0237 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) YPA_0238 ENOG4108I5U Uridine phosphorylase YPA_0241 ENOG4108KF1 Membrane YPA_0242 ENOG4105CGY Dna recombination protein YPA_0244 ENOG4105JC1 sterol-binding domain protein YPA_0246 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) YPA_0248 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) YPA_0254 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase YPA_0257 ENOG41063M6 Cell Division Protein YPA_0258 ENOG4105ETE Transcriptional regulator (LacI family YPA_0259 ENOG4105C25 Primosomal protein n' YPA_0261 ENOG4108Z12 YiaAB two helix domain-containing protein YPA_0263 ENOG4105C28 cystathionine YPA_0264 ENOG4105C28 cystathionine YPA_0265 ENOG4105CFH Aspartokinase YPA_0266 ENOG4105SYT Methylenetetrahydrofolate reductase YPA_0267 ENOG4105DQ6 Transposase YPA_0269 ENOG4105CT4 transporter YPA_0271 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) YPA_0272 ENOG4105DUU IucA IucC family protein YPA_0288 ENOG4105CDV Ompa motb domain protein YPA_0290 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPA_0304 ENOG4105CXN decarboxylase YPA_0305 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPA_0306 ENOG4105C2J ABC transporter YPA_0307 ENOG4105CNN ABC, transporter YPA_0312 ENOG4105CEN a g-specific adenine glycosylase YPA_0314 ENOG41090ED Protein with unknown function (DUF469) YPA_0315 ENOG4105CSV Glutaminase YPA_0316 ENOG4105K33 Periplasmic Protein YPA_0317 ENOG4105K33 Periplasmic Protein YPA_0318 ENOG4105EUK rtx toxin RtxA YPA_0319 ENOG4105CSA Coproporphyrinogen iii oxidase YPA_0320 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) YPA_0322 ENOG4108VIA integral membrane protein YPA_0323 ENOG4105II7 pyrroline-5-carboxylate reductase YPA_0324 ENOG4105DFA alanine racemase domain protein YPA_0325 ENOG4105CZX twitching motility protein YPA_0327 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) YPA_0330 ENOG4105D7Z glutathione synthase YPA_0331 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) YPA_0333 ENOG4105RWS endonuclease I YPA_0336 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) YPA_0337 ENOG4108RS6 transposase YPA_0339 ENOG4108K0D peptidase, M48 YPA_0340 ENOG4105CV1 Transketolase (EC 2.2.1.1) YPA_0341 ENOG4108RS6 transposase YPA_0344 ENOG4105D2N Aldolase YPA_0345 ENOG4105D64 Mechanosensitive ion channel YPA_0350 ENOG4105MPN Membrane YPA_0352 ENOG4105E66 phosphoriboisomerase A YPA_0353 ENOG4108JQ1 Dehydrogenase YPA_0354 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase YPA_0357 ENOG4107RAQ aminopeptidase YPA_0358 ENOG4105D0A hydroxylase YPA_0359 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family YPA_0368 ENOG4108UT2 hemolysin iii YPA_0371 ENOG4105Y75 tpr repeat protein YPA_0373 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPA_0374 ENOG4105EB3 Histidine kinase YPA_0375 ENOG4105CT7 inner membrane cred family protein YPA_0376 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) YPA_0377 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPA_0378 ENOG4105T95 Thiol disulfide interChange protein YPA_0379 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) YPA_0385 ENOG4105DFP Integrase YPA_0390 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation YPA_0391 ENOG4105WJ3 XRE family Transcriptional regulator YPA_0407 ENOG4105NTW Transcriptional regulator YPA_0408 ENOG4108UY0 (LipO)protein YPA_0410 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPA_0411 ENOG4105CNN ABC, transporter YPA_0414 ENOG4107FKK extracellular solute-binding protein family 1 YPA_0416 ENOG4105EG2 ABC transporter, permease YPA_0418 ENOG4105C4C beta-galactosidase YPA_0419 ENOG4105CI1 PTS System YPA_0421 ENOG4105ETE Transcriptional regulator (LacI family YPA_0423 ENOG4105DPW Major facilitator superfamily MFS_1 YPA_0424 ENOG4105ETE Transcriptional regulator (LacI family YPA_0426 ENOG4105D2N Aldolase YPA_0428 ENOG4105ENH Sulfatase YPA_0429 ENOG4105C4X radical SAM domain protein YPA_0431 ENOG4105CHR reductase YPA_0432 ENOG4105CE4 GlcNAc 6-P deacetylase YPA_0433 ENOG4108YTN IIa component YPA_0434 ENOG4105F3R pts system mannose fructose sorbose family iid YPA_0435 ENOG4105ETZ PTS System YPA_0436 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB YPA_0437 ENOG4105E70 isomerase YPA_0438 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of YPA_0439 ENOG4105E98 transcriptional regulator DeoR family YPA_0440 ENOG4105CBG Sulfatase YPA_0441 ENOG4108RS6 transposase YPA_0444 ENOG4108RS6 transposase YPA_0450 ENOG4107B2H carbonic anhydrase YPA_0454 ENOG4107QHF type ii secretion system protein e YPA_0455 ENOG4105D7Q type ii secretion system YPA_0467 ENOG4105C8Q Methyl-accepting chemotaxis YPA_0470 ENOG4105EJC lysr family transcriptional regulator YPA_0471 ENOG4105F27 Major Facilitator YPA_0472 ENOG4105RQF LysR family Transcriptional regulator YPA_0473 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) YPA_0474 ENOG41060NJ transcriptional regulator YPA_0479 ENOG4105CPC Aldo Keto reductase YPA_0483 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase YPA_0490 ENOG4105DSY exodeoxyribonuclease V, gamma YPA_0491 ENOG4107QXK peptidase YPA_0492 ENOG4107QKA exodeoxyribonuclease V beta YPA_0493 ENOG4107QYX exodeoxyribonuclease v alpha YPA_0495 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase YPA_0496 ENOG4105CA3 membrane-bound lytic murein transglycosylase YPA_0497 ENOG4105CUZ uba thif-type nad fad binding protein YPA_0498 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) YPA_0499 ENOG4105C9B Cysteine desulfurase YPA_0500 ENOG4105ETT transcriptional Regulator, LysR family YPA_0501 ENOG4105M08 Membrane YPA_0507 ENOG4105EWT decarboxylase family YPA_0510 ENOG4108RS6 transposase YPA_0511 ENOG4105WP7 tRNA pseudouridine synthase C YPA_0512 ENOG4105DR9 pseudouridine synthase YPA_0513 ENOG4105QDK Flavodoxin YPA_0517 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) YPA_0521 ENOG4108RS6 transposase YPA_0525 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) YPA_0526 ENOG4105KNE Phosphatidate cytidylyltransferase YPA_0527 ENOG4105DZP Membrane-associated zinc metalloprotease YPA_0529 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) YPA_0533 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) YPA_0535 ENOG4105C0B DNA polymerase III (alpha subunit) YPA_0537 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase YPA_0538 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) YPA_0540 ENOG4105M1T rho-binding antiterminator YPA_0542 ENOG4108VWS Yaeq family YPA_0543 ENOG4108YZN class I peptide chain release factor YPA_0544 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion YPA_0546 ENOG4108R96 Methyltransferase, YaeB family YPA_0547 ENOG4108R8X outer membrane lipoprotein YPA_0548 ENOG4105D01 (LipO)protein YPA_0549 ENOG4108UMI ABC transporter, permease YPA_0551 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase YPA_0553 ENOG4105CV8 reductase YPA_0556 ENOG4105E9H Lytic Murein transglycosylase YPA_0558 ENOG4105D1A Methyltransferase YPA_0560 ENOG4108JDX DNA polymerase iii, epsilon subunit YPA_0561 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease YPA_0566 ENOG4105VUH addiction module killer protein YPA_0577 ENOG4105DFP Integrase YPA_0578 ENOG4108RS6 transposase YPA_0580 ENOG4108Z1B Cyclase dehydrase YPA_0582 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPA_0583 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) YPA_0584 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) YPA_0586 ENOG4105BZN citrate synthase YPA_0587 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit YPA_0588 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein YPA_0590 ENOG4105E33 succinate dehydrogenase YPA_0591 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 YPA_0592 ENOG4105C7S Dehydrogenase YPA_0594 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha YPA_0595 ENOG4105C4M (Ubiquinol oxidase) subunit I YPA_0596 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii YPA_0597 ENOG4105KJB cyd operon protein YbgE YPA_0598 ENOG4107YD3 Thioesterase YPA_0599 ENOG4105E02 MotA TolQ exbB proton channel YPA_0600 ENOG4105M8F Biopolymer transport protein exbD tolR YPA_0601 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA YPA_0601 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA YPA_0603 ENOG4105KCK Peptidoglycan-associated lipoprotein YPA_0604 ENOG4105UFD tol-pal system protein YbgF YPA_0606 ENOG4106Z1T Nicotinamide Mononucleotide Transporter YPA_0607 ENOG4105PGM cation diffusion facilitator family transporter YPA_0608 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPA_0611 ENOG4105DZ1 carboxypeptidase YPA_0612 ENOG4105C44 Serine transporter YPA_0613 ENOG4107FB0 transcriptional regulator DeoR family YPA_0614 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPA_0615 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase YPA_0617 ENOG4105D0C transport protein YPA_0618 ENOG41090BQ Glutaredoxin YPA_0619 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress YPA_0620 ENOG4108RMJ sensory transduction regulator YPA_0621 ENOG4107RUE extracellular solute-binding protein family 1 YPA_0622 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPA_0623 ENOG4105F38 ABC transporter, permease YPA_0624 ENOG4105D38 putrescine abc transporter YPA_0625 ENOG4105RBQ inner membrane protein ybjO YPA_0627 ENOG4106TNF Periplasmic binding protein YPA_0630 ENOG4105DQ5 transport system permease protein YPA_0631 ENOG4105E0A ABC, transporter YPA_0632 ENOG410642S Nicotianamine synthase protein YPA_0633 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) YPA_0634 ENOG4108I0N Transporter, RarD family, DMT superfamily protein YPA_0636 ENOG4105DMR ABC, transporter YPA_0637 ENOG4105GBT ABC transporter YPA_0638 ENOG4106PMH Extracellular solute-binding protein family 3 YPA_0639 ENOG4105E5Z arginine transporter ATP-binding subunit YPA_0640 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) YPA_0642 ENOG41064MM (LipO)protein YPA_0643 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase YPA_0644 ENOG4105CGD Nad-dependent epimerase dehydratase YPA_0645 ENOG4105C5W Aldolase YPA_0647 ENOG4105C7K acetolactate synthase YPA_0648 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) YPA_0650 ENOG4105DWU Membrane YPA_0651 ENOG4105CPB ATP-dependent endonuclease of the OLD family YPA_0652 ENOG4108MJ5 VirK protein YPA_0654 ENOG4105DJY efflux transporter, rnd family, mfp subunit YPA_0656 ENOG4105VEQ Cold shock protein YPA_0658 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPA_0659 ENOG4108RS6 transposase YPA_0660 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) YPA_0662 ENOG4108JJ8 (ABC) transporter YPA_0663 ENOG4108JJ9 ABC, transporter YPA_0664 ENOG4105C3M thioredoxin reductase YPA_0665 ENOG4105EW9 transcriptional regulator AsnC family YPA_0666 ENOG4105CNU cell division protein FtsK YPA_0668 ENOG4105D1H recombination factor protein RarA YPA_0670 ENOG4108ISG Major Facilitator YPA_0671 ENOG4108ISG Major Facilitator YPA_0672 ENOG4105F1A Pyruvate formate-lyase YPA_0674 ENOG4105C6N Formate acetyltransferase YPA_0675 ENOG4105TMB Formate nitrite transporter YPA_0676 ENOG4105DDY UPF0142 protein ycaO YPA_0677 ENOG4105HDK L-asparaginase YPA_0678 ENOG4105EUR Domain-Containing protein YPA_0678 ENOG4105EUR Domain-Containing protein YPA_0683 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) YPA_0685 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 YPA_0688 ENOG4105E32 cytoplasmic protein YPA_0691 ENOG4105E32 cytoplasmic protein YPA_0692 ENOG4105VEQ Cold shock protein YPA_0693 ENOG4105W49 UPF0434 protein YPA_0695 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups YPA_0696 ENOG4106371 Methyltransferase YPA_0697 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) YPA_0698 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) YPA_0700 ENOG4108RS6 transposase YPA_0701 ENOG4105DIT ErfK YbiS YcfS YnhG family protein YPA_0702 ENOG4105EAQ (twin-arginine translocation) pathway signal YPA_0703 ENOG4105C5X domain protein YPA_0704 ENOG4105CGF Aromatic amino acid aminotransferase YPA_0709 ENOG4105CD8 aminopeptidase N YPA_0711 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) YPA_0712 ENOG4105QVC MOSC domain-containing protein YPA_0714 ENOG4105C5H ABC transporter YPA_0715 ENOG4105F1S paraquat-inducible protein a YPA_0716 ENOG4105DY2 Paraquat-inducible protein b YPA_0717 ENOG4108Q2G (LipO)protein YPA_0718 ENOG4108RS6 transposase YPA_0719 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPA_0722 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPA_0724 ENOG4105DAN ATP-dependent protease YPA_0726 ENOG4108RS6 transposase YPA_0727 ENOG4105UYK outer membrane protein a YPA_0729 ENOG4108RZ1 DNA transformation protein YPA_0730 ENOG4105EM2 membrane YPA_0731 ENOG410901E Membrane YPA_0732 ENOG41088T4 Helicase IV YPA_0734 ENOG4108Q67 UPF0319 protein YPA_0735 ENOG4105K4P CoA-binding domain protein YPA_0739 ENOG4108Z0T Part of a sulfur-relay system (By similarity) YPA_0740 ENOG4108BUD transposase YPA_0747 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) YPA_0748 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPA_0749 ENOG4105CHR reductase YPA_0750 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase YPA_0752 ENOG4108KQ6 Enoyl-CoA hydratase YPA_0753 ENOG4105CHR reductase YPA_0755 ENOG41062T2 Acyl carrier protein YPA_0756 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase YPA_0763 ENOG4105CDV Ompa motb domain protein YPA_0765 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPA_0787 ENOG4105C5H ABC transporter YPA_0790 ENOG4105D06 uba thif-type nad fad binding protein YPA_0791 ENOG4105CVM Molybdenum cofactor synthesis domain protein YPA_0793 ENOG4105C19 ABC transporter YPA_0794 ENOG4105ENT Efflux transporter rnd family, mfp subunit YPA_0798 ENOG4105EGI Transcriptional regulator YPA_0799 ENOG4105CBP Major Facilitator YPA_0801 ENOG4105DHF Membrane YPA_0804 ENOG4108HWV )-transporter YPA_0805 ENOG4107GZ4 SanA protein YPA_0808 ENOG41067MG lrgb family YPA_0810 ENOG4105E5W Transporter YPA_0815 ENOG4108RS6 transposase YPA_0817 ENOG4105D1F ATP-binding protein YPA_0820 ENOG4108GAE asmA family YPA_0821 ENOG4105EE5 Membrane protein terC YPA_0822 ENOG4108819 ferric iron reductase YPA_0823 ENOG4105DY8 decarboxylase YPA_0824 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) YPA_0826 ENOG4105DUU IucA IucC family protein YPA_0827 ENOG4105E0A ABC, transporter YPA_0828 ENOG4105TVJ transport system, permease YPA_0829 ENOG4105DQ5 transport system permease protein YPA_0830 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) YPA_0831 ENOG4105CNM Receptor YPA_0832 ENOG4105DUU IucA IucC family protein YPA_0834 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase YPA_0835 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase YPA_0836 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) YPA_0837 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase YPA_0840 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) YPA_0842 ENOG4105ECC imidazole-glycerol-phosphate dehydratase YPA_0844 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) YPA_0846 ENOG4108535 NAD dependent epimerase/dehydratase family YPA_0848 ENOG4105CNN ABC, transporter YPA_0849 ENOG4105C2J ABC transporter YPA_0850 ENOG4105C2J ABC transporter YPA_0851 ENOG4107SCQ Iron-containing alcohol dehydrogenase YPA_0852 ENOG4105CUB amino acid YPA_0853 ENOG4105CJB Exodeoxyribonuclease I YPA_0857 ENOG4105TNG K13735 adhesin invasin YPA_0859 ENOG4105CSP Major Facilitator Superfamily YPA_0860 ENOG4105KIR Thiol-disulfide oxidoreductase dcc YPA_0861 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr YPA_0863 ENOG4105DIA mandelate racemase muconate lactonizing YPA_0867 ENOG4105UQX Mate efflux family protein YPA_0871 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme YPA_0872 ENOG4108KX4 response regulator YPA_0873 ENOG4105CG6 trap dicarboxylate transporter dctm subunit YPA_0875 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit YPA_0876 ENOG4108TSE Transferase YPA_0879 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) YPA_0881 ENOG4105EQR Transposase IS116 IS110 IS902 YPA_0882 ENOG4105C1J atp-dependent rna helicase YPA_0883 ENOG4108RS6 transposase YPA_0885 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) YPA_0887 ENOG41061WM D-Alanyl-D-Alanine YPA_0888 ENOG4105CXG d-lactate dehydrogenase YPA_0890 ENOG4105N1F Hnh endonuclease YPA_0893 ENOG4105Y3U Transglycosylase-associated protein YPA_0895 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein YPA_0898 ENOG4108W15 Protein of unknown function (DUF1456) YPA_0900 ENOG4105C32 Amino acid ABC transporter (Permease) YPA_0901 ENOG4105CNN ABC, transporter YPA_0902 ENOG4108JJB ABC transporter YPA_0903 ENOG4108IV0 ABC, transporter YPA_0906 ENOG4105KHC sulfurtransferase YPA_0907 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system YPA_0908 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system YPA_0909 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component YPA_0910 ENOG4108IJ8 ABC transporter YPA_0911 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component YPA_0912 ENOG4105D5Q Arginine ornithine antiporter YPA_0913 ENOG4105CXN decarboxylase YPA_0915 ENOG4105FDR Membrane YPA_0920 ENOG4105DVT helicase YPA_0921 ENOG4105CH6 catalase YPA_0922 ENOG4108UII YfaZ family YPA_0923 ENOG4105E0U tyrosine-specific transport protein YPA_0926 ENOG4105XPH Ferredoxin YPA_0927 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPA_0928 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPA_0930 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPA_0931 ENOG4105BZU Histidine kinase YPA_0932 ENOG41068CG regulatoR YPA_0933 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC YPA_0934 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC YPA_0935 ENOG4106UW1 Major Facilitator superfamily YPA_0936 ENOG4105FCK Membrane YPA_0937 ENOG4108RS6 transposase YPA_0938 ENOG4108RS6 transposase YPA_0939 ENOG4107R6D beta-lactam binding protein AmpH YPA_0941 ENOG4105CT4 transporter YPA_0943 ENOG4105C8Q Methyl-accepting chemotaxis YPA_0945 ENOG4105Y50 Virulence Protein YPA_0948 ENOG4105HRS Antitermination protein YPA_0949 ENOG4105G63 Type III effector Hrp-dependent YPA_0951 ENOG4105MVE transcriptional regulator YPA_0952 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) YPA_0956 ENOG4105TKZ Tail Sheath YPA_0964 ENOG4108T86 baseplate J family protein YPA_0968 ENOG4108Q3X Transcriptional regulator YPA_0969 ENOG4105CS2 ec 3.2.1.21 YPA_0973 ENOG4105GMB type VI secretion system effector, hcp1 family YPA_0976 ENOG4105GMB type VI secretion system effector, hcp1 family YPA_0978 ENOG4105E68 Sulfatase YPA_0979 ENOG4105PAN UPF0352 protein YPA_0981 ENOG4108RS6 transposase YPA_0983 ENOG4105CFI type iii restriction protein res subunit YPA_0984 ENOG4105I08 Pseudouridine synthase YPA_0985 ENOG4105C2C drug resistance transporter, Bcr CflA YPA_0987 ENOG4105HG6 YPA_0988 ENOG4108JQ5 ABC transporter YPA_0989 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component YPA_0990 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component YPA_0991 ENOG4105E43 Extracellular solute-binding protein, family 5 YPA_0992 ENOG4105CXC rtn protein YPA_0993 ENOG4107TT5 NLP P60 protein YPA_0994 ENOG41076MN Phosphoesterase, PA-phosphatase related YPA_0995 ENOG4105CKI cobalamin synthesis protein YPA_0997 ENOG4107YCY Transcriptional regulator YPA_0998 ENOG4105DEI Mannitol dehydrogenase YPA_1002 ENOG4105KRS Proteinase inhibitor YPA_1003 ENOG4105CHR reductase YPA_1006 ENOG4105DQ6 Transposase YPA_1008 ENOG4105C26 Dehydrogenase YPA_1010 ENOG4105E66 phosphoriboisomerase A YPA_1012 ENOG4105C2J ABC transporter YPA_1013 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane YPA_1015 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein YPA_1016 ENOG4105DE4 1-phosphofructokinase YPA_1017 ENOG4105DM4 PTS System YPA_1018 ENOG4108SGD regulatory protein YPA_1021 ENOG4108UIF Chaperone YPA_1022 ENOG4108D1K outer membrane usher protein YPA_1024 ENOG4105HMI Membrane YPA_1025 ENOG4105DUM transcriptional regulator, lysR family YPA_1026 ENOG4108IQI permease YPA_1028 ENOG4105EHG Permease protein YPA_1030 ENOG4105D05 Receptor YPA_1031 ENOG4108TGY Glutathione S-transferase YPA_1034 ENOG4105D01 (LipO)protein YPA_1036 ENOG4108UMI ABC transporter, permease YPA_1037 ENOG4105DZ1 carboxypeptidase YPA_1040 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPA_1043 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) YPA_1046 ENOG4105F0Z galactose-1-phosphate uridylyltransferase YPA_1047 ENOG4105CMR udp-glucose 4-epimerase YPA_1049 ENOG4105DKW ABC transporter YPA_1050 ENOG4105F4R Transcriptional regulator mode YPA_1051 ENOG410680R Protein of unknown function (DUF2592) YPA_1052 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein YPA_1053 ENOG4105E0C molybdate abc transporter YPA_1055 ENOG4108K4B hydrolase YPA_1060 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) YPA_1061 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) YPA_1062 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) YPA_1064 ENOG4105VYA Uncharacterized conserved protein (DUF2132) YPA_1065 ENOG4105CHW UPF0052 protein YPA_1066 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) YPA_1068 ENOG4105M00 molybdopterin converting factor, subunit 1 YPA_1069 ENOG4108ZAF Molybdopterin YPA_1070 ENOG4105HFZ Membrane YPA_1071 ENOG4105HFZ Membrane YPA_1072 ENOG4108RS6 transposase YPA_1076 ENOG4105C94 Transporter YPA_1077 ENOG4105CN8 Transcriptional regulator YPA_1079 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) YPA_1080 ENOG4105EAA nucleoside YPA_1081 ENOG4108RS6 transposase YPA_1082 ENOG4105EAA nucleoside YPA_1084 ENOG4105BZU Histidine kinase YPA_1086 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPA_1090 ENOG4107QWP ABC-2 type transporter YPA_1091 ENOG4107QWP ABC-2 type transporter YPA_1092 ENOG4105CJ1 ABC, transporter YPA_1094 ENOG4107MVR Transcriptional regulator YPA_1095 ENOG4105C1J atp-dependent rna helicase YPA_1109 ENOG4105BZ1 (ABC) transporter YPA_1112 ENOG4105N4N Protein of unknown function (DUF2766) YPA_1113 ENOG4105TIK YPA_1114 ENOG41064PC YPA_1117 ENOG4105C85 amino acid YPA_1119 ENOG410610J Protein of unknown function (DUF2627) YPA_1120 ENOG4105VEQ Cold shock protein YPA_1121 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase YPA_1122 ENOG4105DHI Methyltransferase YPA_1124 ENOG4105BZU Histidine kinase YPA_1128 ENOG4105F3R pts system mannose fructose sorbose family iid YPA_1129 ENOG4105ETZ PTS System YPA_1130 ENOG4108EQA pts system YPA_1131 ENOG4105EE5 Membrane protein terC YPA_1132 ENOG4108V8F Transcriptional regulator, MarR family YPA_1135 ENOG4105C26 Dehydrogenase YPA_1136 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase YPA_1141 ENOG4105EFA 4-hydroxyphenylacetate YPA_1142 ENOG4107UWN reductase YPA_1143 ENOG4105EJQ L-serine dehydratase YPA_1145 ENOG4105CRQ synthase (Component I) YPA_1148 ENOG4105C1J atp-dependent rna helicase YPA_1149 ENOG4105X2V dna damage-inducible protein YPA_1152 ENOG4105CUG Oligopeptidase b YPA_1157 ENOG4105MPK DNA polymerase III subunit theta YPA_1158 ENOG41090A1 ferritin YPA_1159 ENOG4105FXM Copper resistance protein YPA_1161 ENOG4105NKT exported protein YPA_1164 ENOG4105D00 flagellar biosynthetic protein flhB YPA_1165 ENOG4105D7B Flagellar biosynthesis protein flha YPA_1166 ENOG4105D7B Flagellar biosynthesis protein flha YPA_1167 ENOG4105W13 flagellar protein YPA_1169 ENOG4108RS6 transposase YPA_1171 ENOG4105QVD Flagella synthesis protein FlgN YPA_1172 ENOG4105M9M anti-sigma28 factor FlgM YPA_1173 ENOG4105CKS Flagella basal body P-ring formation protein flgA YPA_1174 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) YPA_1175 ENOG4108ZC9 flagellar basal-body rod protein flgc YPA_1176 ENOG4105W00 Flagellar hook capping protein YPA_1177 ENOG4105BZE flagellar hook protein, FlgE YPA_1178 ENOG4108KPB Flagellar basal-body rod protein FlgF YPA_1179 ENOG4105CGA flagellar basal-body rod protein FlgG YPA_1182 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj YPA_1183 ENOG4105E1Q flagellar hook-associated protein YPA_1184 ENOG4105DTJ flagellar hook-associated protein YPA_1185 ENOG4105DKT Transcriptional regulator YPA_1187 ENOG4105CNN ABC, transporter YPA_1189 ENOG4105C2J ABC transporter YPA_1190 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane YPA_1191 ENOG4108MGF sugar kinase YPA_1194 ENOG4105D19 Role in flagellar biosynthesis (By similarity) YPA_1195 ENOG4105VS8 Flagellar biosynthetic protein fliq YPA_1196 ENOG4105CN7 Flagellar biosynthetic protein FliP YPA_1198 ENOG4105DD5 Flagellar motor switch protein YPA_1199 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) YPA_1200 ENOG4107ZI8 flagellar basal body-associated protein flil YPA_1201 ENOG4105WF4 Flagellar hook-length control protein YPA_1202 ENOG4105GSA Flagellar export protein flij YPA_1203 ENOG4108JIR Flagellum-specific ATP synthase YPA_1204 ENOG41090PJ Flagellar assembly protein YPA_1205 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) YPA_1206 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) YPA_1207 ENOG4105VQ0 flagellar hook-basal body complex protein fliE YPA_1211 ENOG4105DHT Metal Dependent Phosphohydrolase YPA_1212 ENOG4108T5G Adenylate YPA_1216 ENOG4105MQ3 flagellar protein FliS YPA_1217 ENOG4105DTS flagellar hook-associated YPA_1218 ENOG4105I03 Flagellin YPA_1219 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPA_1220 ENOG4108M9K flagella biosynthesis protein FliZ YPA_1221 ENOG4105K6H D-cysteine desulfhydrase YPA_1222 ENOG4105EAB amino acid AbC transporter YPA_1223 ENOG4105E5Q amino acid AbC transporter YPA_1224 ENOG4105CDA abc transporter atp-binding protein YPA_1229 ENOG4105C26 Dehydrogenase YPA_1231 ENOG4105CK7 Sodium proline symporter YPA_1234 ENOG4105DBE peroxidase YPA_1235 ENOG4105DBE peroxidase YPA_1238 ENOG4105C85 amino acid YPA_1239 ENOG4108T1M outer membrane protein x YPA_1241 ENOG4105RA2 Membrane YPA_1242 ENOG4105XVG cytoplasmic protein YPA_1243 ENOG4105WH1 Two component transcriptional regulator luxr family YPA_1249 ENOG4108WC9 type VI secretion system effector, hcp1 family YPA_1266 ENOG4105FDP GntR family transcriptional regulator YPA_1268 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) YPA_1271 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component YPA_1272 ENOG4108IJ9 (ABC) transporter YPA_1284 ENOG4107ZSV Receptor YPA_1285 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase YPA_1289 ENOG4105C0W non-ribosomal peptide synthetase YPA_1292 ENOG4105BZ1 (ABC) transporter YPA_1293 ENOG4105EYM Major Facilitator superfamily YPA_1296 ENOG4108MQF Chaperone YPA_1298 ENOG4105CW0 outer membrane usher protein YPA_1302 ENOG4105BZU Histidine kinase YPA_1303 ENOG4108Q9V regulatoR YPA_1304 ENOG4105CYC Transferase YPA_1305 ENOG4105DJG MaoC domain protein dehydratase YPA_1310 ENOG4107RGD Major Facilitator superfamily YPA_1314 ENOG4107RGD Major Facilitator superfamily YPA_1317 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPA_1318 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family YPA_1319 ENOG4105C85 amino acid YPA_1320 ENOG4105MVE transcriptional regulator YPA_1322 ENOG4105CSV Glutaminase YPA_1324 ENOG4107SJW iron permease, FTR1 YPA_1327 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) YPA_1329 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) YPA_1333 ENOG4105H1N peptidase, M24 YPA_1334 ENOG4108TUY outer membrane protein PgaA YPA_1335 ENOG4107BJW polysaccharide deacetylase YPA_1336 ENOG4105CND Glycosyl transferase, family 2 YPA_1337 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD YPA_1340 ENOG4105D5M phosphate starvation-inducible protein YPA_1341 ENOG4105EWV Sodium calcium exchanger membrane region YPA_1342 ENOG4105BZU Histidine kinase YPA_1343 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family YPA_1352 ENOG4105FCK Membrane YPA_1355 ENOG4105CZE histidine utilization repressor YPA_1356 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) YPA_1357 ENOG41090B9 response to stress YPA_1359 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) YPA_1360 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) YPA_1361 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase YPA_1374 ENOG4108WF3 methyltransferase YPA_1382 ENOG4105GR3 Histidine kinase YPA_1384 ENOG4105ENX hydrolase YPA_1393 ENOG4105C3G gtp-binding protein YPA_1395 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria YPA_1396 ENOG4105C5T Phosphoribosyl pyrophosphate synthase YPA_1402 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) YPA_1403 ENOG4108YY7 Invasion gene expression up-regulator SirB YPA_1404 ENOG41063JG Transcriptional regulator YPA_1406 ENOG4105CHH sulfate transporter YPA_1409 ENOG4105CHH sulfate transporter YPA_1412 ENOG4105EG2 ABC transporter, permease YPA_1413 ENOG4105F38 ABC transporter, permease YPA_1415 ENOG4108RS6 transposase YPA_1416 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPA_1417 ENOG4108QXE glycerophosphoryl diester phosphodiesterase YPA_1418 ENOG4105E2R ROK family YPA_1420 ENOG4107XHZ cytoplasmic chaperone TorD family protein YPA_1421 ENOG4105F3T (LipO)protein YPA_1423 ENOG4105D9U N-acetyltransferase YPA_1425 ENOG4105CJR Integral membrane protein (MviN YPA_1429 ENOG4106ZCM YecM protein YPA_1433 ENOG4105WJG Glutathione YPA_1434 ENOG41081XQ Conserved Protein YPA_1436 ENOG4108TIT dATP pyrophosphohydrolase YPA_1439 ENOG4108RS6 transposase YPA_1442 ENOG4105FAV ABC, transporter YPA_1444 ENOG4105NXV High-affinity zinc uptake system protein YPA_1445 ENOG4105DR5 peptidase YPA_1446 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase YPA_1447 ENOG4105CA9 Pyruvate kinase YPA_1448 ENOG4106KNT transcriptional regulator YPA_1449 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase YPA_1450 ENOG4108UHU Aldolase YPA_1453 ENOG4105M4H endoribonuclease L-psp YPA_1454 ENOG4105DVT helicase YPA_1455 ENOG41072GX Peptidase M22 Glycoprotease YPA_1456 ENOG4105Y4Z Outer Membrane Lipoprotein YPA_1457 ENOG4105CEY Amp-dependent synthetase and ligase YPA_1458 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) YPA_1459 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) YPA_1460 ENOG4107QMS site-determining protein YPA_1463 ENOG4105CVE Lytic murein transglycosylase YPA_1464 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase YPA_1466 ENOG4107R08 Integrase YPA_1482 ENOG4108RS6 transposase YPA_1493 ENOG4105UZW Tail fiber assembly protein YPA_1498 ENOG4105C3J Cysteine desulfurase YPA_1504 ENOG4105ED1 spovr family YPA_1506 ENOG4105CNH Multidrug resistance protein MdtL YPA_1507 ENOG4105EUB pirin domain protein YPA_1508 ENOG4105HEI LysR family (Transcriptional regulator YPA_1511 ENOG4105CYN Serine protein kinase YPA_1512 ENOG4105GNX MltA-interacting MipA family protein YPA_1513 ENOG4105DSB aldose 1-epimerase YPA_1516 ENOG4105VUT cytoplasmic protein YPA_1517 ENOG4108RWI nicotinamidase YPA_1518 ENOG4105HDK L-asparaginase YPA_1519 ENOG4105D07 Signal peptide peptidase, SppA YPA_1520 ENOG41069NU Nitroreductase YPA_1521 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) YPA_1522 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) YPA_1523 ENOG4105MTM Protein of unknown function (DUF1496) YPA_1524 ENOG4105M6F mutator MutT protein YPA_1525 ENOG4105CGK Exodeoxyribonuclease III YPA_1526 ENOG4105SKE transcriptional Regulator LysR family YPA_1529 ENOG4105CIY formyltetrahydrofolate deformylase YPA_1531 ENOG4105I93 response regulator YPA_1532 ENOG4105C6Y Udp-glucose 6-dehydrogenase YPA_1534 ENOG4107104 thymidine kinase YPA_1537 ENOG4108EKI Dehydrogenase YPA_1538 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein YPA_1539 ENOG4107QSI ABC, transporter YPA_1541 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPA_1542 ENOG4105C3U ABC transporter YPA_1543 ENOG4108JQ7 (ABC) transporter YPA_1547 ENOG4108T1M outer membrane protein x YPA_1551 ENOG4105K9H YciI-like protein YPA_1552 ENOG410822N TonB family YPA_1554 ENOG4105NAU thioesterase Superfamily protein YPA_1560 ENOG4105EIF outer membrane protein W YPA_1565 ENOG4105DK0 Indole-3-glycerol phosphate synthase YPA_1567 ENOG4105DDQ anthranilate synthase YPA_1569 ENOG4105DB7 PHP domain protein YPA_1570 ENOG4107RTD sua5 ycio yrdc ywlc family protein YPA_1571 ENOG4105FE9 pseudouridine synthase YPA_1572 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase YPA_1573 ENOG4105UBK short-chain dehydrogenase reductase YPA_1574 ENOG4105ERU peptidase YPA_1575 ENOG4105RKX Protein of unknown function (DUF2498) YPA_1577 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) YPA_1578 ENOG4107R11 Transcriptional regulator YPA_1580 ENOG4107QM5 aconitate hydratase YPA_1581 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) YPA_1583 ENOG4105EYK Phosphatidylglycerophosphatase B YPA_1584 ENOG4105Q4A inner membrane protein yciS YPA_1585 ENOG4105CFV Tetratricopeptide repeat protein YPA_1588 ENOG4108ZJT translation initiation factor, Sui1 YPA_1589 ENOG41061RM osmotically inducible lipoprotein YPA_1590 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase YPA_1592 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) YPA_1593 ENOG4105VCD cytoplasmic protein YPA_1594 ENOG4105D22 carbon starvation protein YPA_1596 ENOG4105CSP Major Facilitator Superfamily YPA_1597 ENOG4105EXW epimerase dehydratase YPA_1598 ENOG4105CSM endonuclease III YPA_1600 ENOG4108UQQ Electron transport complex YPA_1601 ENOG4105D6A Electron transport complex YPA_1602 ENOG4105UEI Transcriptional Regulator AraC Family YPA_1606 ENOG4105M9B inner membrane protein ydgK YPA_1608 ENOG4108JJA ABC, transporter YPA_1609 ENOG4108JJA ABC, transporter YPA_1611 ENOG4105C42 Type I secretion membrane fusion protein (HlyD YPA_1612 ENOG4108JJA ABC, transporter YPA_1615 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator YPA_1617 ENOG4105CNN ABC, transporter YPA_1619 ENOG4105D9R oxidoreductase YPA_1620 ENOG4105DHU Bile acid YPA_1622 ENOG4106J39 exported protein YPA_1623 ENOG4105EIP mannose-6-phosphate isomerase YPA_1624 ENOG4105C9Q fumarate hydratase class II YPA_1625 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) YPA_1626 ENOG4105D94 Major Facilitator Superfamily YPA_1627 ENOG4106NZI LysR family Transcriptional regulator YPA_1628 ENOG4105DAG ROK family YPA_1629 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) YPA_1630 ENOG41060NJ transcriptional regulator YPA_1635 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component YPA_1637 ENOG4105FYV Amp nucleosidase YPA_1642 ENOG4105C7K acetolactate synthase YPA_1643 ENOG4105M71 acetolactate synthase 1 regulatory subunit YPA_1644 ENOG4105PAD Hydrolase YPA_1648 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) YPA_1649 ENOG4105DS0 Transcriptional regulator, Crp Fnr family YPA_1650 ENOG4105Q9Y Universal stress protein YPA_1651 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) YPA_1652 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) YPA_1653 ENOG4105C5D exported protein YPA_1654 ENOG4105D5Q Arginine ornithine antiporter YPA_1656 ENOG4107EXC regulatoR YPA_1657 ENOG4105JJR Histidine kinase YPA_1658 ENOG4105CTD carboxy-peptidase YPA_1659 ENOG4108RS6 transposase YPA_1664 ENOG4105DS1 cytochrome b561 YPA_1666 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap YPA_1668 ENOG4105CQ7 ATP-dependent helicase YPA_1671 ENOG4105CQ7 ATP-dependent helicase YPA_1673 ENOG4105DKT Transcriptional regulator YPA_1674 ENOG4105DEI Mannitol dehydrogenase YPA_1675 ENOG4105WXT Conserved Protein YPA_1676 ENOG410689M (LipO)protein YPA_1677 ENOG4107H52 Dicarboxylate transport YPA_1678 ENOG4105C5I Dehydrogenase YPA_1679 ENOG41090X5 Heat shock protein hslJ YPA_1681 ENOG4105KT7 mgtC SapB transporter YPA_1683 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) YPA_1688 ENOG4107QSI ABC, transporter YPA_1689 ENOG4105KXI murein peptide amidase A YPA_1690 ENOG4107S8C mandelate racemase muconate lactonizing YPA_1691 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) YPA_1692 ENOG4108RS6 transposase YPA_1697 ENOG4105CM6 amino acid regulated cytosolic protein YPA_1699 ENOG4105FM1 phage shock protein C YPA_1700 ENOG4105YYT phage shock protein B YPA_1701 ENOG41087YS Phage shock protein A YPA_1702 ENOG4105E51 psp operon transcriptional activator YPA_1703 ENOG4108RS6 transposase YPA_1704 ENOG4108HIY periplasmic YPA_1705 ENOG4108I5W peptide transport system, permease protein YPA_1706 ENOG4108EU3 peptide transport system, permease YPA_1707 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein YPA_1708 ENOG4108JQ2 peptide transport system atp-binding protein YPA_1709 ENOG4105Q4T oxidoreductase YPA_1710 ENOG4105DUX Transporter YPA_1711 ENOG41069YE inner membrane protein yohC YPA_1712 ENOG4108ZR5 Conserved Protein YPA_1713 ENOG4108K3A Glutathione S-transferase YPA_1717 ENOG410642K Lysozyme inhibitor YPA_1719 ENOG4108XTF Outer Membrane Lipoprotein YPA_1721 ENOG4107RGM aldo keto reductase YPA_1722 ENOG4105XZD Fe-S protein YPA_1723 ENOG4105DIJ Phosphoethanolamine transferase YPA_1724 ENOG4108WUH Transcriptional regulator, TetR family YPA_1725 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPA_1727 ENOG4108UYE Lactoylglutathione lyase YPA_1728 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) YPA_1729 ENOG4105M2J Glutaredoxin YPA_1730 ENOG4105K4H Nlp p60 protein YPA_1731 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) YPA_1733 ENOG4105F52 Transcriptional regulator YPA_1734 ENOG4105CZQ inner membrane transport protein YdhC YPA_1735 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase YPA_1736 ENOG4108R6K riboflavin synthase, subunit alpha YPA_1738 ENOG4105CA9 Pyruvate kinase YPA_1739 ENOG4105KMX major outer membrane lipoprotein YPA_1740 ENOG4108RS6 transposase YPA_1743 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein YPA_1746 ENOG4105JRK feS assembly protein SufD YPA_1747 ENOG4105C3K feS assembly ATPase SufC YPA_1748 ENOG4105DIW FeS assembly protein SUFB YPA_1749 ENOG4108Z4V iron-sulfur cluster assembly YPA_1750 ENOG4105KA0 thioesterase Superfamily protein YPA_1751 ENOG4105CQB FAD linked oxidase domain protein YPA_1752 ENOG4105IPI Membrane YPA_1753 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) YPA_1755 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPA_1759 ENOG4108QBX (LipO)protein YPA_1767 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) YPA_1768 ENOG4108V06 Glutathione peroxidase YPA_1771 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) YPA_1772 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) YPA_1779 ENOG41087WU YPA_1783 ENOG4105DSE periplasmic solute binding protein YPA_1784 ENOG4105DIK (ABC) transporter YPA_1785 ENOG4105CC5 ABC transporter YPA_1786 ENOG4105CC5 ABC transporter YPA_1788 ENOG4105FGM Fructosamine kinase YPA_1789 ENOG4107PN8 YfeABCD locus regulator YPA_1790 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 YPA_1792 ENOG4105M5J Cupin 2, conserved barrel domain protein YPA_1794 ENOG4105CHR reductase YPA_1795 ENOG41061NF Pectate lyase YPA_1798 ENOG41061NF Pectate lyase YPA_1799 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component YPA_1800 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component YPA_1802 ENOG4105WEM extracellular solute-binding protein YPA_1803 ENOG4108PU9 oligogalacturonate-specific porin YPA_1804 ENOG4107K5X Membrane-bound metal-dependent hydrolase YPA_1805 ENOG4108ETY sodium dicarboxylate symporter YPA_1806 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPA_1808 ENOG4105CAZ oligogalacturonide lyase YPA_1809 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPA_1810 ENOG4108VEV chaperone YPA_1813 ENOG4108VEV chaperone YPA_1814 ENOG4105H8W Fimbrial protein YPA_1816 ENOG4105CN1 protease YPA_1818 ENOG4108ZGC gaf domain protein YPA_1819 ENOG4105H2K paraquat-inducible protein a YPA_1820 ENOG4105DY2 Paraquat-inducible protein b YPA_1824 ENOG4105GQR Chaperone YPA_1827 ENOG4105WT8 Protein of unknown function (DUF1480) YPA_1835 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) YPA_1838 ENOG4105EUR Domain-Containing protein YPA_1839 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPA_1841 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) YPA_1842 ENOG4108VYJ response regulator receiver protein YPA_1844 ENOG4105BZU Histidine kinase YPA_1845 ENOG4105C8Q Methyl-accepting chemotaxis YPA_1846 ENOG4105C8Q Methyl-accepting chemotaxis YPA_1850 ENOG4105WWK YheO domain protein YPA_1852 ENOG4105KME endoribonuclease L-psp YPA_1853 ENOG4105R9B Major Facilitator YPA_1854 ENOG4108V3W Chemotaxis protein, CheW YPA_1855 ENOG4105CBS Chea signal transduction histidine kinase YPA_1856 ENOG4105ER2 Ompa motb domain protein YPA_1857 ENOG4107RD7 Flagellar Motor Protein, MotA YPA_1858 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region YPA_1859 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) YPA_1860 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic YPA_1861 ENOG4105KT7 mgtC SapB transporter YPA_1862 ENOG4105C8Q Methyl-accepting chemotaxis YPA_1863 ENOG4105C8Q Methyl-accepting chemotaxis YPA_1865 ENOG4105VEQ Cold shock protein YPA_1870 ENOG4105GSJ Inner membrane protein ylaC YPA_1872 ENOG4108XM1 transcriptional regulator AsnC family YPA_1874 ENOG41061EV selenium-binding protein YdfZ YPA_1875 ENOG4105D6F Phosphatase YPA_1878 ENOG4105KVH Transcriptional regulator YPA_1879 ENOG4105ECR NmrA family YPA_1880 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor YPA_1882 ENOG4106NDP Transcriptional regulator YPA_1883 ENOG4108HMX isocitrate dehydrogenase (NADP) YPA_1884 ENOG4108R99 pseudouridine synthase YPA_1888 ENOG4107QTF adenylosuccinate lyase YPA_1890 ENOG4105XJC Two component transcriptional regulator (Winged helix family YPA_1892 ENOG4105EZE Cupin 4 family protein YPA_1894 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) YPA_1897 ENOG4105D60 lipoprotein releasing system transmembrane protein YPA_1899 ENOG4105D60 lipoprotein releasing system transmembrane protein YPA_1900 ENOG4108JA2 transcriptioN-repair coupling factor YPA_1901 ENOG4107MBR 17 kDa surface antigen YPA_1905 ENOG4105CEP NADH dehydrogenase YPA_1907 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) YPA_1910 ENOG41090DQ Lipoprotein YPA_1911 ENOG4105K59 histidine triad (HIT) protein YPA_1912 ENOG4105F9E Shikimate 5-dehydrogenase YPA_1913 ENOG4108RS6 transposase YPA_1916 ENOG4108RS6 transposase YPA_1917 ENOG4105CI1 PTS System YPA_1918 ENOG4105F8V Hydrolase, tatD family YPA_1919 ENOG4107QRG dna polymerase iii YPA_1921 ENOG4105HHA aminodeoxychorismate lyase YPA_1922 ENOG4105YAZ 4-amino-4-deoxychorismate lyase YPA_1923 ENOG4108RS6 transposase YPA_1924 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPA_1926 ENOG4105CHR reductase YPA_1927 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase YPA_1930 ENOG4105VGS 50s ribosomal protein l32 YPA_1931 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein YPA_1933 ENOG4108RS6 transposase YPA_1934 ENOG4105EI2 Pseudouridine synthase YPA_1935 ENOG4107QQB Ribonuclease E YPA_1937 ENOG4105D5G Transposase YPA_1939 ENOG41067V3 Antibiotic biosynthesis monooxygenase YPA_1942 ENOG4105PVA Biofilm formation regulatory protein BssS YPA_1944 ENOG4105D5G Transposase YPA_1947 ENOG4105WH1 Two component transcriptional regulator luxr family YPA_1948 ENOG4105DSF transport protein YPA_1954 ENOG4107YC3 synthase YPA_1955 ENOG4105VJY transcriptional regulator YPA_1956 ENOG4105ETT transcriptional Regulator, LysR family YPA_1957 ENOG4105C54 Major Facilitator superfamily YPA_1959 ENOG4105CPC Aldo Keto reductase YPA_1960 ENOG4108Y1S CRISPR-associated protein, Csy4 family YPA_1961 ENOG4105M6W Crispr-associated protein, Csy3 family YPA_1962 ENOG4105DZX CRISPR-associated protein, Csy2 family YPA_1963 ENOG4105ENG CRISPR-associated protein, Csy1 family YPA_1964 ENOG4107IIZ CRISPR-associated helicase, Cas3 YPA_1965 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) YPA_1966 ENOG4105CUY Mechanosensitive ion channel YPA_1970 ENOG4105HY2 Glycosidase related protein YPA_1971 ENOG4105DRS transport system, permease YPA_1974 ENOG4105ETE Transcriptional regulator (LacI family YPA_1976 ENOG4108IJ9 (ABC) transporter YPA_1979 ENOG4105CKT filamentous hemagglutinin YPA_1983 ENOG4105CKT filamentous hemagglutinin YPA_1986 ENOG4105CKT filamentous hemagglutinin YPA_1987 ENOG4105D5K Hemolysin activator protein YPA_1988 ENOG4105E3J oxidoreductase YPA_1989 ENOG4105DVW rieske (2Fe-2S) YPA_1990 ENOG4105C94 Transporter YPA_1991 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) YPA_1992 ENOG4105EJC lysr family transcriptional regulator YPA_1993 ENOG4105FKQ transcriptional regulator YPA_1994 ENOG4105CNN ABC, transporter YPA_1995 ENOG4105C2J ABC transporter YPA_1996 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPA_1997 ENOG4105CPQ Dehydrogenase YPA_2004 ENOG4107R0W ABC transporter YPA_2005 ENOG4105E5Q amino acid AbC transporter YPA_2006 ENOG4105CDA abc transporter atp-binding protein YPA_2007 ENOG4107SDU Methyl-accepting chemotaxis YPA_2012 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction YPA_2014 ENOG4108MTB glycosyl transferase family YPA_2015 ENOG4105CEY Amp-dependent synthetase and ligase YPA_2017 ENOG4108IPT Naphthoate synthase YPA_2020 ENOG4105E4F Isochorismate synthase YPA_2022 ENOG4105TNS Conserved Protein YPA_2025 ENOG4105C01 Dihydroxy-acid dehydratase YPA_2028 ENOG4105C5I Dehydrogenase YPA_2029 ENOG4105K2J Transcriptional regulator YPA_2030 ENOG4105F32 YngK protein YPA_2031 ENOG4105CHR reductase YPA_2032 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family YPA_2033 ENOG4108R66 Conserved Protein YPA_2036 ENOG4105C8S subunit m YPA_2037 ENOG4105D65 subunit l YPA_2039 ENOG4107UFS subunit j YPA_2042 ENOG4108IEH NADH dehydrogenase subunit g YPA_2043 ENOG4107QIZ NADH dehydrogenase YPA_2044 ENOG4105GKE subunit e YPA_2046 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) YPA_2048 ENOG4107NQ8 LysR family Transcriptional regulator YPA_2049 ENOG4105CHM Aminotransferase YPA_2051 ENOG4107QWE )-transporter YPA_2052 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 YPA_2056 ENOG4105C6K Malic enzyme YPA_2057 ENOG4107P2S Transcriptional regulator YPA_2060 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC YPA_2061 ENOG4105PTV Nudix Hydrolase YPA_2062 ENOG4108RE9 Phosphodiesterase YPA_2064 ENOG4105ECP epimerase YPA_2065 ENOG4108JEH abc transporter atp-binding protein YPA_2066 ENOG4106YG3 ABC transporter YPA_2067 ENOG4105DSP amino acid AbC transporter YPA_2068 ENOG4105E89 ABC transporter YPA_2071 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YPA_2072 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase YPA_2073 ENOG4105E96 Colicin v production protein YPA_2074 ENOG4108S3P Sporulation domain protein YPA_2075 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase YPA_2077 ENOG4105DQR SNARE associated Golgi YPA_2079 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) YPA_2082 ENOG410631K Membrane YPA_2083 ENOG4106WZ1 flagella biosynthesis regulator YPA_2086 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPA_2088 ENOG4105MH2 YfcL protein YPA_2089 ENOG4108BPE -transporting atpase YPA_2090 ENOG4105EJ9 Membrane YPA_2093 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) YPA_2096 ENOG4108BY2 phosphohistidine phosphatase YPA_2099 ENOG4105KZW UPF0381 protein YPA_2100 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation YPA_2101 ENOG410903C (LipO)protein YPA_2102 ENOG4105KWW Biogenesis protein YPA_2103 ENOG4105KWW Biogenesis protein YPA_2104 ENOG4107QX9 Thiol disulfide interChange protein YPA_2105 ENOG4105DA4 cytochrome c-type biogenesis protein YPA_2107 ENOG4105X3C heme exporter protein YPA_2108 ENOG41060IM Heme exporter protein YPA_2109 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) YPA_2112 ENOG4108V0P LemA family YPA_2114 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA YPA_2120 ENOG4105CS6 Rhs element vgr protein YPA_2132 ENOG4105CW0 outer membrane usher protein YPA_2134 ENOG4105CW0 outer membrane usher protein YPA_2135 ENOG4105GQR Chaperone YPA_2137 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPA_2147 ENOG4105CVE Lytic murein transglycosylase YPA_2152 ENOG4108WC9 type VI secretion system effector, hcp1 family YPA_2154 ENOG4107QY8 reductase YPA_2155 ENOG4105QAX Iron-sulfur YPA_2156 ENOG4107KGK dmso reductase anchor subunit YPA_2157 ENOG4108NEM leader-binding protein dmsD YPA_2159 ENOG4107Y60 (LipO)protein YPA_2161 ENOG4106B0W Curli production assembly transport component CsgG YPA_2163 ENOG4108VKM cytochrome b561 YPA_2164 ENOG4105CHM Aminotransferase YPA_2165 ENOG41072TH Protein of unknown function (DUF1479) YPA_2168 ENOG4105C5Q Transcriptional regulator YPA_2169 ENOG4105CPC Aldo Keto reductase YPA_2172 ENOG4105D9N nucleoside YPA_2174 ENOG4108RS6 transposase YPA_2177 ENOG4105VRT cytoplasmic protein YPA_2181 ENOG4105EXN Sulfate transport protein CysZ YPA_2182 ENOG4105C6T cysteine synthase YPA_2183 ENOG4105KZ7 phosphocarrier protein hpr YPA_2185 ENOG4105C5Y PTS System YPA_2186 ENOG4108RS6 transposase YPA_2187 ENOG4105E0F Histidine kinase YPA_2188 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPA_2189 ENOG4105DJY efflux transporter, rnd family, mfp subunit YPA_2192 ENOG4105E1V na solute symporter YPA_2193 ENOG4107RAQ aminopeptidase YPA_2195 ENOG4105C87 Aminotransferase class I and II YPA_2197 ENOG41062D9 Histidine kinase YPA_2198 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPA_2200 ENOG4105C6T cysteine synthase YPA_2201 ENOG4108IJ6 ABC transporter YPA_2202 ENOG4105ECW sulfate abc transporter YPA_2203 ENOG4108I5D sulfate abc transporter YPA_2204 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein YPA_2206 ENOG4105QEK Transcriptional regulator YPA_2207 ENOG4108R66 Conserved Protein YPA_2213 ENOG4105EZR dyp-type peroxidase family protein YPA_2214 ENOG4105E7K (LipO)protein YPA_2215 ENOG4105H4F exported protein YPA_2222 ENOG4105C6K Malic enzyme YPA_2227 ENOG4105CUW cytochrome C-TYPE protein YPA_2228 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) YPA_2230 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase YPA_2231 ENOG4108ZNS ferredoxin-type protein NapF YPA_2232 ENOG4105WH1 Two component transcriptional regulator luxr family YPA_2234 ENOG4105BZS acriflavin resistance protein YPA_2236 ENOG4105S2T inner membrane protein YbcI YPA_2237 ENOG4105C4X radical SAM domain protein YPA_2238 ENOG4105ENH Sulfatase YPA_2239 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPA_2240 ENOG4107Z33 ABC transporter, permease YPA_2241 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC YPA_2243 ENOG4105KUZ arsenate reductase YPA_2249 ENOG4105CGZ zinc metallopeptidase YPA_2251 ENOG4108RS6 transposase YPA_2252 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPA_2254 ENOG4105RH4 Glycine cleavage system transcriptional repressor YPA_2255 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen YPA_2259 ENOG4105C02 permease YPA_2260 ENOG4105ERG peptidase m48, ste24p YPA_2261 ENOG4105K89 arsenate reductase YPA_2263 ENOG4108RS6 transposase YPA_2266 ENOG4108V3E phosphoribosylglycinamide formyltransferase YPA_2267 ENOG4108MK9 spermidine N(1)-acetyltransferase YPA_2268 ENOG4108C80 FliB family YPA_2269 ENOG4108C80 FliB family YPA_2271 ENOG4105E2Z phosphate ABC transporter (Permease YPA_2272 ENOG4105C8U phosphate abc transporter YPA_2273 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) YPA_2274 ENOG4105C9X ppx gppa phosphatase YPA_2275 ENOG4105CJW magnesium transporter YPA_2276 ENOG4105R8A Heat shock protein YPA_2280 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component YPA_2281 ENOG4105F38 ABC transporter, permease YPA_2283 ENOG4108JPW Aminotransferase YPA_2285 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPA_2290 ENOG4105EB3 Histidine kinase YPA_2291 ENOG4105EB3 Histidine kinase YPA_2292 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPA_2293 ENOG4105KWI UPF0339 protein YPA_2294 ENOG4105CFP Peptidase U32 YPA_2296 ENOG4108ZGU inhibitor of vertebrate lysozyme YPA_2299 ENOG4105DWF phosphomethylpyrimidine kinase YPA_2308 ENOG4108WC9 type VI secretion system effector, hcp1 family YPA_2309 ENOG4108RS6 transposase YPA_2310 ENOG4108RS6 transposase YPA_2312 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) YPA_2316 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPA_2317 ENOG4105N21 Membrane YPA_2326 ENOG4108MGN ATP-binding component of a transport system YPA_2327 ENOG4108MGN ATP-binding component of a transport system YPA_2329 ENOG4105YYA enhanced serine sensitivity protein SseB YPA_2331 ENOG4105WVQ Fe-S assembly protein IscX YPA_2332 ENOG4108ZIT Ferredoxin, 2FE-2S YPA_2333 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB YPA_2336 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins YPA_2337 ENOG4105C3J Cysteine desulfurase YPA_2341 ENOG4105D7X high-affinity nickel-transporter YPA_2342 ENOG41065CD Exported protein YPA_2343 ENOG4108MN2 Stationary phase inducible protein CsiE YPA_2344 ENOG4105D8G Major Facilitator superfamily YPA_2348 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) YPA_2349 ENOG4108M21 YPA_2350 ENOG4108M21 YPA_2351 ENOG4108YZA Nitrogen regulatory protein pii YPA_2352 ENOG4105C4K Nad synthetase YPA_2353 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPA_2354 ENOG4108SKK alpha helix protein YPA_2355 ENOG4107WP9 Histidine kinase YPA_2356 ENOG4108RS6 transposase YPA_2362 ENOG4108Z6B deaminase YPA_2363 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB YPA_2365 ENOG4106G6Q Transcriptional regulator YPA_2366 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding YPA_2367 ENOG4108RS6 transposase YPA_2369 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) YPA_2373 ENOG4105GIJ Glycine betaine YPA_2374 ENOG4108HQS Glycine betaine YPA_2375 ENOG4108IJ7 Glycine betaine YPA_2376 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPA_2381 ENOG4108WMJ Protein of unknown function (DUF2002) YPA_2384 ENOG4108SAJ Protein of unknown function (DUF1198) YPA_2386 ENOG4105VEQ Cold shock protein YPA_2387 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein YPA_2388 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPA_2389 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPA_2390 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) YPA_2391 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) YPA_2397 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) YPA_2402 ENOG4105XXV Acid-resistance protein YPA_2403 ENOG4107SVH Potassium channel protein YPA_2404 ENOG41086WQ Protein CrcB homolog YPA_2405 ENOG41085Q9 Protein CrcB homolog YPA_2407 ENOG4105VZJ PTS System YPA_2408 ENOG4105CK1 PTS System YPA_2409 ENOG4105VCP PTS System YPA_2410 ENOG4105EZV Transcriptional regulator YPA_2414 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 YPA_2418 ENOG4105EEX Two component transcriptional regulator (Winged helix family YPA_2419 ENOG4105C08 Histidine kinase YPA_2424 ENOG4105XIQ Protein of unknown function (DUF2517) YPA_2425 ENOG4107SEY Conserved Protein YPA_2426 ENOG4105CVP deoxyribo-dipyrimidine photolyase YPA_2427 ENOG4107RF4 Phosphodiesterase YPA_2428 ENOG4107QNR UPF0135 protein YPA_2429 ENOG4105P4J Allophanate hydrolase, subunit 1 YPA_2430 ENOG4105P4J Allophanate hydrolase, subunit 1 YPA_2431 ENOG4107R7A Allophanate hydrolase subunit 2 YPA_2442 ENOG4105C1J atp-dependent rna helicase YPA_2444 ENOG4108IYU L-aspartate oxidase YPA_2446 ENOG41069PW sigma-e factor negative regulatory protein YPA_2447 ENOG4105VQK sigma E regulatory protein, MucB RseB YPA_2448 ENOG4105WMJ Positive regulator of sigma E, RseC MucC YPA_2451 ENOG4105C3F Signal peptidase i YPA_2457 ENOG4105DFP Integrase YPA_2460 ENOG4105EV9 Alpha Beta Hydrolase YPA_2461 ENOG4105NNH LexA regulated protein YPA_2462 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) YPA_2463 ENOG41090R7 Ferric uptake YPA_2468 ENOG4108RS6 transposase YPA_2469 ENOG4105CI1 PTS System YPA_2471 ENOG4105CE4 GlcNAc 6-P deacetylase YPA_2472 ENOG4105E2R ROK family YPA_2473 ENOG4105D4U had-superfamily hydrolase, subfamily iia YPA_2474 ENOG4105CAQ asparagine synthetase YPA_2476 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family YPA_2478 ENOG4105C9A Phoh family YPA_2480 ENOG4108JU5 Magnesium and cobalt efflux protein YPA_2481 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) YPA_2482 ENOG4107RP9 extracellular solute-binding protein, family 3 YPA_2483 ENOG4105EAD ABC transporter YPA_2484 ENOG4105DRP amino acid AbC transporter YPA_2485 ENOG4105CDA abc transporter atp-binding protein YPA_2486 ENOG4107PAI alpha helical protein YPA_2489 ENOG4105DJF DNA polymerase III, delta' subunit YPA_2491 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) YPA_2493 ENOG4105CJN penicillin-binding protein YPA_2494 ENOG4105CNI cell division protein FtsW YPA_2495 ENOG4105K6T rare lipoprotein A YPA_2498 ENOG4105DZ1 carboxypeptidase YPA_2502 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) YPA_2503 ENOG4107Z6W Protein CrcB homolog YPA_2504 ENOG4105VEQ Cold shock protein YPA_2506 ENOG4108N8T regulatoR YPA_2511 ENOG4108JJ7 ABC transporter YPA_2513 ENOG4105DH8 myo-inositol catabolism YPA_2516 ENOG4105EDK PfkB domain protein YPA_2517 ENOG4105CK5 oxidoreductase YPA_2518 ENOG4105CNN ABC, transporter YPA_2519 ENOG4105C2J ABC transporter YPA_2520 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPA_2521 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) YPA_2523 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) YPA_2524 ENOG4105C26 Dehydrogenase YPA_2528 ENOG4105DN3 alpha-2-macroglobulin domain protein YPA_2529 ENOG4108JQB penicillin-binding protein 1C YPA_2531 ENOG4108JQB penicillin-binding protein 1C YPA_2532 ENOG4105HVQ Regulatory factor of maltose metabolism YPA_2538 ENOG4108WC9 type VI secretion system effector, hcp1 family YPA_2543 ENOG4105EZE Cupin 4 family protein YPA_2548 ENOG4107QK4 glycoside hydrolase, family 3 domain protein YPA_2552 ENOG4107SET aldo keto reductase YPA_2553 ENOG4105EQ2 LysR family Transcriptional regulator YPA_2558 ENOG41077RS Phosphatase YPA_2559 ENOG4105E8V Alpha Beta Hydrolase Fold protein YPA_2561 ENOG4108HPI phosphatidate Cytidylyltransferase YPA_2562 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase YPA_2566 ENOG4105WQ3 Rna-binding protein YPA_2567 ENOG4108RS6 transposase YPA_2569 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) YPA_2571 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) YPA_2572 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit YPA_2573 ENOG4105CV6 ABC transporter, permease YPA_2574 ENOG4108I0Y (ABC) transporter YPA_2575 ENOG4108UJV acyl-CoA thioesterase i YPA_2576 ENOG4105E1F short-chain dehydrogenase reductase YPA_2577 ENOG4107QR8 Thioredoxin YPA_2578 ENOG4107QX8 SPFH domain, Band 7 family protein YPA_2579 ENOG4105G5H Membrane YPA_2580 ENOG4108Z6Z Transcriptional regulator YPA_2581 ENOG4105C59 p-type ATPase YPA_2582 ENOG4105MBR gumn family YPA_2583 ENOG4108Z66 YbaK ebsC protein YPA_2585 ENOG4105CGH 5'-nucleotidase YPA_2586 ENOG4105CGH 5'-nucleotidase YPA_2587 ENOG4105CGH 5'-nucleotidase YPA_2588 ENOG4105EU0 Major facilitator Superfamily YPA_2589 ENOG4105CKD glutathione-regulated potassium-efflux system protein YPA_2590 ENOG4107RE1 Inosine-guanosine kinase YPA_2591 ENOG4108QY5 Ferric enterobactin transport protein YPA_2594 ENOG4105CJT Mannose-1-phosphate guanylyltransferase YPA_2595 ENOG4105C30 Nad-dependent epimerase dehydratase YPA_2596 ENOG4105C0K Gdp-mannose 4,6-dehydratase YPA_2597 ENOG4105C0K Gdp-mannose 4,6-dehydratase YPA_2598 ENOG4108TJN glycosyl transferase group 1 YPA_2604 ENOG4108SMP Nad-dependent epimerase dehydratase YPA_2605 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase YPA_2606 ENOG4105FAW cDP-glucose 4,6-dehydratase YPA_2607 ENOG4105FAW cDP-glucose 4,6-dehydratase YPA_2608 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase YPA_2609 ENOG4108EX3 reductase YPA_2616 ENOG4107QMP dna polymerase iii subunits gamma and tau YPA_2618 ENOG4105WD1 Membrane YPA_2620 ENOG4106428 Protein of unknown function (DUF2496) YPA_2621 ENOG4105EGS Mechanosensitive ion channel YPA_2624 ENOG4105EGS Mechanosensitive ion channel YPA_2625 ENOG41090EX DsrE family YPA_2626 ENOG4108IG5 Transcriptional regulator YPA_2627 ENOG4105C1P efflux transporter, rnd family, mfp subunit YPA_2628 ENOG4105BZS acriflavin resistance protein YPA_2630 ENOG4105YK5 50S ribosomal protein L36 YPA_2632 ENOG4108UKR Biofilm formation regulator YbaJ YPA_2633 ENOG4105KF5 hemolysin expression-modulating protein YPA_2634 ENOG41080UX Methyltransferase YPA_2635 ENOG4108MNP Glycoprotein polysaccharide metabolism YPA_2636 ENOG4105C29 acyl-CoA thioesterase YPA_2637 ENOG4105BZU Histidine kinase YPA_2638 ENOG4108YZA Nitrogen regulatory protein pii YPA_2639 ENOG4105BZ1 (ABC) transporter YPA_2640 ENOG4105BZ1 (ABC) transporter YPA_2641 ENOG4108XM1 transcriptional regulator AsnC family YPA_2642 ENOG4105C6T cysteine synthase YPA_2644 ENOG4108NFA extracellular solute-binding protein YPA_2646 ENOG4108TGP Thioesterase superfamily protein YPA_2647 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein YPA_2648 ENOG4105EIN peptidylprolyl cis-trans isomerase YPA_2649 ENOG4105K70 DNA-binding protein YPA_2650 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) YPA_2654 ENOG4105M85 Bola protein YPA_2655 ENOG4105IEY (LipO)protein YPA_2656 ENOG4105EYM Major Facilitator superfamily YPA_2657 ENOG4108NFH Sugar hydrolase YPA_2658 ENOG4105E2S oxidase) subunit II YPA_2659 ENOG4105BZ9 Cytochrome C oxidase, subunit I YPA_2660 ENOG4105CCU oxidase (Subunit III) YPA_2661 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) YPA_2663 ENOG4107RDB Major Facilitator YPA_2665 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) YPA_2666 ENOG4107S0N DJ-1 family YPA_2670 ENOG4105CTB Polyprenyl synthetase YPA_2672 ENOG4108RS6 transposase YPA_2673 ENOG4108ZAI phosphatidylglycerophosphatase a YPA_2674 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) YPA_2677 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) YPA_2681 ENOG4108RS6 transposase YPA_2682 ENOG4108RS6 transposase YPA_2683 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) YPA_2684 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) YPA_2685 ENOG4105VIE preprotein translocase, subunit YajC YPA_2687 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) YPA_2688 ENOG4108ZYK Acyl carrier protein phosphodiesterase YPA_2689 ENOG4105D3R alkyl hydroperoxide reductase YPA_2692 ENOG4105CHR reductase YPA_2693 ENOG4107R28 alpha amylase, catalytic region YPA_2694 ENOG4105C85 amino acid YPA_2695 ENOG4105CWM branched-chain amino acid transport system II carrier protein YPA_2697 ENOG4105BZU Histidine kinase YPA_2698 ENOG4105CK6 Two component transcriptional regulator (Winged helix family YPA_2699 ENOG4107RH8 nuclease SbcCD subunit D YPA_2700 ENOG4105EYH Exonuclease YPA_2703 ENOG4105EYH Exonuclease YPA_2704 ENOG4105DKQ ROK family YPA_2709 ENOG4105F2W methyltransferase YPA_2719 ENOG4108KB2 LysR family Transcriptional regulator YPA_2720 ENOG4105CIN aminoacyl-histidine dipeptidase YPA_2724 ENOG4105CJ2 (LipO)protein YPA_2728 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPA_2729 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPA_2730 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPA_2732 ENOG4105F7V ErfK ybiS ycfS ynhG family protein YPA_2733 ENOG4105E7A Glutamine amidotransferase YPA_2735 ENOG4107QPN acyl-Coa dehydrogenase YPA_2737 ENOG4106YJS accessory processing protein YPA_2741 ENOG4105C5R Aminotransferase YPA_2744 ENOG4105C5R Aminotransferase YPA_2746 ENOG4105E5Q amino acid AbC transporter YPA_2754 ENOG4105EQ0 Major Facilitator superfamily YPA_2755 ENOG4108UMN azlc family YPA_2756 ENOG4105ZED uncharacterized protein ygaH YPA_2757 ENOG4105NTK Transcriptional repressor Mpra YPA_2758 ENOG4105CW7 secretion protein, HlyD family YPA_2759 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPA_2760 ENOG4105EIB trna rrna methyltransferase YPA_2761 ENOG4105K63 Thioredoxin YPA_2762 ENOG4106IUH DTW domain containing protein YPA_2763 ENOG4105CD5 CoA-binding domain protein YPA_2764 ENOG4105JIM Phosphatidylserine synthase YPA_2765 ENOG4105T42 (LipO)protein YPA_2766 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPA_2767 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase YPA_2768 ENOG4105C34 Pseudouridine synthase YPA_2769 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane YPA_2770 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA YPA_2771 ENOG4108RS6 transposase YPA_2772 ENOG4108RS6 transposase YPA_2773 ENOG4105CQC Prephenate dehydratase YPA_2779 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) YPA_2780 ENOG4105N0Z inner membrane protein ygbE YPA_2782 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) YPA_2787 ENOG4108K5P (LipO)protein YPA_2788 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPA_2791 ENOG4108YZG isomerase YPA_2792 ENOG4105CPQ Dehydrogenase YPA_2793 ENOG4105CHR reductase YPA_2794 ENOG4105CMT Dihydroxyacetone kinase YPA_2796 ENOG4105DKT Transcriptional regulator YPA_2800 ENOG4105E89 ABC transporter YPA_2801 ENOG4105CA0 peroxidase YPA_2803 ENOG4105D05 Receptor YPA_2807 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) YPA_2809 ENOG4107GFK fumarate YPA_2810 ENOG4105CMG Carbohydrate kinase YPA_2811 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase YPA_2812 ENOG4105F5R ABC transporter YPA_2813 ENOG4105CNN ABC, transporter YPA_2814 ENOG4105C2J ABC transporter YPA_2815 ENOG4108RS6 transposase YPA_2817 ENOG4105E98 transcriptional regulator DeoR family YPA_2818 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase YPA_2819 ENOG4107QY8 reductase YPA_2820 ENOG4105QAX Iron-sulfur YPA_2821 ENOG4107KGK dmso reductase anchor subunit YPA_2822 ENOG4108NEM leader-binding protein dmsD YPA_2823 ENOG4105CPW cytochrome b561 YPA_2824 ENOG4108XVM Cytochrome b(562) YPA_2828 ENOG4105C2J ABC transporter YPA_2829 ENOG4105CNN ABC, transporter YPA_2830 ENOG4108HHA Transketolase YPA_2831 ENOG4108IUS Transketolase YPA_2832 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) YPA_2841 ENOG4107VXZ Hydrolase YPA_2842 ENOG4105W39 Membrane YPA_2843 ENOG4105D9M gamma-glutamylcysteine synthetase YPA_2845 ENOG4108RS6 transposase YPA_2846 ENOG4108JU6 CBS domain protein YPA_2847 ENOG4106KVJ cytochrome C assembly protein YPA_2848 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY YPA_2853 ENOG4108RS6 transposase YPA_2854 ENOG4108NE3 Salt-induced outer membrane protein YPA_2855 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPA_2856 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPA_2857 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPA_2858 ENOG4108NEV two component transcriptional regulator, LytTR family YPA_2859 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPA_2860 ENOG4105EHE chorismate mutase- prephenate dehydrogenase YPA_2871 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase YPA_2872 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) YPA_2876 ENOG4105DXN mazG family YPA_2877 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) YPA_2878 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) YPA_2880 ENOG4105BZU Histidine kinase YPA_2881 ENOG4105C0H protease YPA_2885 ENOG4105EN6 Membrane YPA_2890 ENOG4105S6R Iron-hydroxamate transporter permease subunit YPA_2891 ENOG4105J76 Periplasmic binding protein YPA_2892 ENOG4105E0A ABC, transporter YPA_2893 ENOG4105BZ4 penicillin-binding protein YPA_2894 ENOG4105CQ7 ATP-dependent helicase YPA_2895 ENOG4107XID 2'-5' rna ligase YPA_2898 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters YPA_2899 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) YPA_2900 ENOG4105DJ0 Poly(A) Polymerase YPA_2901 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YPA_2905 ENOG4107BJW polysaccharide deacetylase YPA_2907 ENOG4105E3A (ABC) transporter YPA_2908 ENOG4105DA5 (ABC) transporter YPA_2909 ENOG41077A9 carbonic anhydrase YPA_2910 ENOG4108UGV hypoxanthine phosphoribosyltransferase YPA_2911 ENOG4105E3B Multicopper oxidase YPA_2912 ENOG4108ZRK uncharacterized protein yacC YPA_2915 ENOG4105RPH Inner membrane protein YddG YPA_2917 ENOG4107QIJ Aconitate hydratase 2 YPA_2918 ENOG4108RS6 transposase YPA_2919 ENOG4107QN2 dihydrolipoyl dehydrogenase YPA_2920 ENOG4107QSN dihydrolipoamide acetyltransferase YPA_2921 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) YPA_2922 ENOG41073TP transcriptional regulator YPA_2923 ENOG4105C85 amino acid YPA_2924 ENOG4106A72 regulatory protein AmpE YPA_2925 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPA_2926 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase YPA_2927 ENOG4108ZUW Major pilin subunit YPA_2928 ENOG4107QHF type ii secretion system protein e YPA_2929 ENOG4105D7Q type ii secretion system YPA_2931 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) YPA_2934 ENOG4108RS6 transposase YPA_2937 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) YPA_2940 ENOG4108K5H permease YjgP YjgQ family protein YPA_2941 ENOG4108M8S permease YjgP YjgQ family protein YPA_2943 ENOG4105MYG DNA polymerase iii, chi subunit YPA_2944 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) YPA_2945 ENOG4108MJ3 acetyltransferase YPA_2946 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) YPA_2948 ENOG4105DBV ornithine carbamoyltransferase YPA_2949 ENOG4105XEP YhcH YjgK YiaL family protein YPA_2952 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPA_2953 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPA_2954 ENOG4105C3U ABC transporter YPA_2955 ENOG4108JQ7 (ABC) transporter YPA_2956 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase YPA_2957 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) YPA_2958 ENOG4107RJJ Transcriptional regulator YPA_2959 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG YPA_2960 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH YPA_2961 ENOG4105EKV Phosphonate metabolism protein YPA_2962 ENOG4105FT8 Phosphonate metabolism YPA_2963 ENOG4105ENV phosphonate C-P lyase system protein PhnK YPA_2964 ENOG4105HRV phosphonate c-p lyase system protein phnl YPA_2965 ENOG4105FD8 phosphonate metabolism protein PhnM YPA_2966 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) YPA_2967 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein YPA_2968 ENOG4105K4T epimerase YPA_2972 ENOG4105DRS transport system, permease YPA_2973 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component YPA_2978 ENOG4108YYD acetyltransferase YPA_2979 ENOG4105XPQ lipid carrier protein YPA_2981 ENOG4105CFP Peptidase U32 YPA_2982 ENOG4106RZ4 Peptidase U32 YPA_2983 ENOG4105ENJ RND efflux system, outer membrane lipoprotein YPA_2984 ENOG4105BZS acriflavin resistance protein YPA_2986 ENOG4105DEN Luciferase family YPA_2990 ENOG4105C1J atp-dependent rna helicase YPA_2993 ENOG4105DQ6 Transposase YPA_2996 ENOG4105C7B Threonine dehydratase YPA_2997 ENOG4105D99 atp gtp-binding protein YPA_2998 ENOG4105D99 atp gtp-binding protein YPA_2999 ENOG4105R2A (LipO)protein YPA_3003 ENOG4105JKW Valine--pyruvate aminotransferase YPA_3005 ENOG4107T9C Alpha amylase catalytic region YPA_3008 ENOG4108ZG0 Ompa motb domain protein YPA_3010 ENOG4108R3E Dna-3-methyladenine glycosylase i YPA_3013 ENOG4106JH6 (LipO)protein YPA_3014 ENOG4105CTS PTS system mannitol-specific YPA_3016 ENOG4105E61 Mannitol repressor protein YPA_3017 ENOG4108YYI Protein of unknown function (DUF2810) YPA_3020 ENOG4105C8Q Methyl-accepting chemotaxis YPA_3023 ENOG4105C8Q Methyl-accepting chemotaxis YPA_3024 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) YPA_3026 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) YPA_3027 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) YPA_3028 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein YPA_3029 ENOG4108MG3 formate dehydrogenase YPA_3032 ENOG4105EM7 Selenocysteine-specific translation elongation factor YPA_3033 ENOG4105D13 transposase YPA_3038 ENOG4105DQ6 Transposase YPA_3040 ENOG4108XTF Outer Membrane Lipoprotein YPA_3044 ENOG4107RD7 Flagellar Motor Protein, MotA YPA_3050 ENOG410804A Flagellar hook-associated 2 domain-containing protein YPA_3054 ENOG4108M3R transcriptional activator CadC YPA_3058 ENOG4105E1Q flagellar hook-associated protein YPA_3060 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) YPA_3061 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) YPA_3062 ENOG4105CGA flagellar basal-body rod protein FlgG YPA_3063 ENOG4108KPB Flagellar basal-body rod protein FlgF YPA_3064 ENOG4105BZE flagellar hook protein, FlgE YPA_3065 ENOG4105W00 Flagellar hook capping protein YPA_3066 ENOG4108ZC9 flagellar basal-body rod protein flgc YPA_3067 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) YPA_3068 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA YPA_3072 ENOG4108JIR Flagellum-specific ATP synthase YPA_3078 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) YPA_3080 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPA_3083 ENOG4105DD5 Flagellar motor switch protein YPA_3084 ENOG4105CN7 Flagellar biosynthetic protein FliP YPA_3085 ENOG4105VS8 Flagellar biosynthetic protein fliq YPA_3086 ENOG4105D19 Role in flagellar biosynthesis (By similarity) YPA_3087 ENOG4105D00 flagellar biosynthetic protein flhB YPA_3092 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein YPA_3094 ENOG4106P2F Pfam:Pili_assembly_C YPA_3095 ENOG4106PG1 outer membrane usher protein YPA_3096 ENOG4108RS6 transposase YPA_3109 ENOG4108ZZF transport protein (ExbD) YPA_3110 ENOG4105CWK Biopolymer transport protein, ExbB YPA_3111 ENOG4105C28 cystathionine YPA_3112 ENOG4108K81 inner membrane protein YghB YPA_3113 ENOG4105CF7 AraC family transcriptional regulator YPA_3114 ENOG4108I6A alcohol dehydrogenase YPA_3115 ENOG4105CV8 reductase YPA_3118 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) YPA_3119 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase YPA_3120 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPA_3121 ENOG4105NF4 modulator of drug activity YPA_3122 ENOG4105CR8 Transcriptional regulator YPA_3123 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPA_3124 ENOG4105IPS esterase YPA_3125 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) YPA_3126 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) YPA_3127 ENOG4108SX3 cytoplasmic protein YPA_3128 ENOG41087AY ADP-Ribose pyrophosphatase YPA_3129 ENOG4105DFG type I secretion outer membrane protein YPA_3131 ENOG4106032 Glutathionylspermidine synthase YPA_3132 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b YPA_3134 ENOG4105W0Z cytoplasmic protein YPA_3135 ENOG4105DVH amino acid YPA_3138 ENOG4105I7R Adenylate cyclase YPA_3139 ENOG4106MWK domain protein YPA_3142 ENOG4107ZVW dihydroneopterin aldolase YPA_3145 ENOG4105VCC 30S ribosomal protein S21 YPA_3146 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) YPA_3147 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPA_3163 ENOG4105KME endoribonuclease L-psp YPA_3168 ENOG4105CHM Aminotransferase YPA_3171 ENOG4105J12 Multidrug resistance protein mdtN YPA_3172 ENOG4108MI0 Resistance protein YPA_3174 ENOG4107QK4 glycoside hydrolase, family 3 domain protein YPA_3176 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component YPA_3178 ENOG4108IJG ABC transporter substrate-binding protein YPA_3179 ENOG4107KJX Transcriptional regulator YPA_3180 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 YPA_3185 ENOG4105CKT filamentous hemagglutinin YPA_3186 ENOG4105CKT filamentous hemagglutinin YPA_3188 ENOG4105CKT filamentous hemagglutinin YPA_3189 ENOG4105CKT filamentous hemagglutinin YPA_3190 ENOG4105CKT filamentous hemagglutinin YPA_3191 ENOG4105D5K Hemolysin activator protein YPA_3192 ENOG4108M24 von Willebrand factor, type A YPA_3195 ENOG4108M24 von Willebrand factor, type A YPA_3198 ENOG4108YK4 Acid-resistance membrane protein YPA_3199 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPA_3202 ENOG4108VKG metal-dependent hydrolase YPA_3203 ENOG4105EE0 oxidoreductase YPA_3205 ENOG4108RS6 transposase YPA_3206 ENOG4105P66 Membrane YPA_3207 ENOG4105CTX dehydratase YPA_3208 ENOG4107QZW Altronate oxidoreductase YPA_3209 ENOG4107QZW Altronate oxidoreductase YPA_3211 ENOG4105DPW Major facilitator superfamily MFS_1 YPA_3214 ENOG4106W5V Membrane YPA_3218 ENOG4105NE1 Conserved Protein YPA_3219 ENOG41090KG Inner membrane protein YqjE YPA_3221 ENOG4108VBZ doxx family YPA_3222 ENOG4105CHF Glutathione S-transferase YPA_3225 ENOG4108Z0R Transferase YPA_3228 ENOG4108WI1 Dna topoisomerase YPA_3230 ENOG4105C79 DNA protecting protein DprA YPA_3234 ENOG4105C1A potassium transporter peripheral membrane YPA_3236 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system YPA_3237 ENOG4105W1Y Transcriptional regulator YPA_3240 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) YPA_3243 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) YPA_3245 ENOG4105VPB 50S ribosomal protein L30 YPA_3254 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal YPA_3256 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) YPA_3259 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) YPA_3268 ENOG4108RS6 transposase YPA_3271 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) YPA_3276 ENOG4105WWK YheO domain protein YPA_3277 ENOG4108V1T peptidylprolyl cis-trans isomerase YPA_3279 ENOG4108YZY peptidylprolyl cis-trans isomerase YPA_3280 ENOG4105VKU nucleicacid-binding protein YPA_3283 ENOG4105C5H ABC transporter YPA_3284 ENOG4105C5H ABC transporter YPA_3285 ENOG4105K64 Glycosyl transferase, family 2 YPA_3287 ENOG4105E2B Taurine dioxygenase YPA_3288 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component YPA_3290 ENOG4106FTQ Taurine ABC transporter, periplasmic YPA_3292 ENOG4105DNZ Alpha Beta Hydrolase YPA_3294 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) YPA_3296 ENOG4108UKZ OsmC family YPA_3298 ENOG410613R integral membrane protein, YccS YhfK family YPA_3299 ENOG4105C8Y Acetylornithine aminotransferase YPA_3301 ENOG4105D7A ATP-binding protein YPA_3302 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) YPA_3303 ENOG4105F8D glycoside hydrolase family 4 YPA_3304 ENOG41060NJ transcriptional regulator YPA_3307 ENOG4105DZC cytosine deaminase YPA_3308 ENOG4107QZF nitrite reductase NADPH large subunit YPA_3309 ENOG4105WZK nitrite reductase NADPH small subunit YPA_3310 ENOG4107V9H nitrite transporter YPA_3312 ENOG4105C31 Tryptophanyl-tRNA synthetase YPA_3313 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) YPA_3314 ENOG4105DJV ribulose-phosphate 3-epimerase YPA_3319 ENOG4105E4G Type IV pilus YPA_3325 ENOG4108JQC penicillin-binding protein 1A YPA_3326 ENOG4107RK2 ADP-ribose diphosphatase NudE YPA_3327 ENOG4105DQY intracellular growth attenuator YPA_3328 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 YPA_3329 ENOG4105VEJ Heat shock protein YPA_3332 ENOG4105E0F Histidine kinase YPA_3333 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPA_3334 ENOG4108RRZ Transcription elongation factor GreB YPA_3335 ENOG4105BZM domain protein YPA_3336 ENOG4105XFK Ferrous iron transport protein A YPA_3337 ENOG4105CE1 Ferrous iron transport protein b YPA_3339 ENOG4105RID UPF0379 protein yhcN YPA_3341 ENOG4105MJ2 Competence protein YPA_3343 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) YPA_3344 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) YPA_3345 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) YPA_3349 ENOG4105E98 transcriptional regulator DeoR family YPA_3353 ENOG4105DQ6 Transposase YPA_3354 ENOG4105BZU Histidine kinase YPA_3356 ENOG4105C1P efflux transporter, rnd family, mfp subunit YPA_3363 ENOG4108RS6 transposase YPA_3366 ENOG4105CFC Transporter YPA_3367 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) YPA_3368 ENOG4107ZSV Receptor YPA_3372 ENOG4105C0W non-ribosomal peptide synthetase YPA_3374 ENOG4105C0W non-ribosomal peptide synthetase YPA_3380 ENOG4105BZ1 (ABC) transporter YPA_3383 ENOG4107EFN gluconate transport system permease 3 YPA_3386 ENOG4105CS6 Rhs element vgr protein YPA_3388 ENOG4105CNA YD repeat protein YPA_3390 ENOG41062WK cellular response to acidity YPA_3391 ENOG4105C8P )-transporter YPA_3392 ENOG4105ETE Transcriptional regulator (LacI family YPA_3394 ENOG4105DQ6 Transposase YPA_3402 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPA_3409 ENOG4105CS6 Rhs element vgr protein YPA_3412 ENOG4105CNA YD repeat protein YPA_3418 ENOG4105CS6 Rhs element vgr protein YPA_3420 ENOG4105CNA YD repeat protein YPA_3428 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase YPA_3429 ENOG4105D4A Cell wall formation (By similarity) YPA_3430 ENOG4108RR8 protoporphyrinogen oxidase YPA_3431 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) YPA_3432 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein YPA_3433 ENOG4108RS6 transposase YPA_3434 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein YPA_3438 ENOG4107QK7 reductase YPA_3440 ENOG4105MDZ Transcriptional activator rfaH YPA_3441 ENOG4105D52 delta-aminolevulinic acid dehydratase YPA_3446 ENOG4108MBX Secretion Protein YPA_3447 ENOG4108JJA ABC, transporter YPA_3448 ENOG4108RS6 transposase YPA_3450 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) YPA_3451 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) YPA_3452 ENOG4105CBT Fructose-1,6-bisphosphatase YPA_3453 ENOG4105DP0 ferredoxin-NADP reductase YPA_3454 ENOG4108VTS Membrane YPA_3455 ENOG4105EBK exported protein YPA_3457 ENOG4107F9Y LysR family transcriptional regulator YPA_3459 ENOG4105JSC dimethylmenaquinone methyltransferase YPA_3460 ENOG4107QPK )-transporter YPA_3462 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein YPA_3467 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPA_3468 ENOG4105FMW periplasmic YPA_3469 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPA_3470 ENOG4105E0F Histidine kinase YPA_3471 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) YPA_3472 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) YPA_3473 ENOG4105D7W serine acetyltransferase YPA_3476 ENOG4105VW4 glutaredoxin 3 YPA_3477 ENOG4107YZP Rhodanese domain protein YPA_3479 ENOG41063SB peptidase YPA_3480 ENOG4105PXI polysaccharide deacetylase YPA_3481 ENOG4105PXI polysaccharide deacetylase YPA_3483 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) YPA_3485 ENOG4105XA0 heptosyltransferase ii YPA_3486 ENOG4105D16 lipopolysaccharide heptosyltransferase i YPA_3487 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase YPA_3491 ENOG4105W0E 50S ribosomal protein L33 YPA_3494 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase YPA_3499 ENOG4105DSJ YicC domain protein YPA_3500 ENOG4105EN6 Membrane YPA_3504 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) YPA_3505 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase YPA_3506 ENOG4105CB5 ATP-dependent DNA helicase recG YPA_3507 ENOG4105D6U Sodium Glutamate Symporter YPA_3508 ENOG4105C2W permease YPA_3509 ENOG4105JV1 AsmA family YPA_3510 ENOG4105SUU thioesterase domain YPA_3514 ENOG4107S2Z UPF0761 membrane protein YPA_3515 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 YPA_3517 ENOG4105C5F glutamine synthetase YPA_3518 ENOG4108RS6 transposase YPA_3519 ENOG4105CUX Signal transduction histidine kinase YPA_3520 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPA_3521 ENOG4105D4P Coproporphyrinogen iii oxidase YPA_3524 ENOG4108RS6 transposase YPA_3525 ENOG4105C2M dna polymerase I YPA_3526 ENOG4108Z33 Thiol disulfide Interchange Protein YPA_3527 ENOG4105E27 serine threonine protein kinase YPA_3528 ENOG4105PC1 Conserved Protein YPA_3530 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b YPA_3536 ENOG4105M6F mutator MutT protein YPA_3541 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) YPA_3542 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) YPA_3543 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) YPA_3547 ENOG4105CNI cell division protein FtsW YPA_3550 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) YPA_3551 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) YPA_3552 ENOG4105CJN penicillin-binding protein YPA_3553 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) YPA_3556 ENOG4108RNS Exports L-alanine (By similarity) YPA_3557 ENOG4107B7Y DNA-binding transcriptional regulator FruR YPA_3558 ENOG4108RS6 transposase YPA_3559 ENOG4108ZP8 Acetolactate synthase small subunit YPA_3560 ENOG4105C7K acetolactate synthase YPA_3561 ENOG4108IQE Amp-dependent synthetase and ligase YPA_3562 ENOG41064T2 transcriptional regulator, lysR family YPA_3563 ENOG4108RS6 transposase YPA_3565 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) YPA_3568 ENOG4105S8Q sugar efflux transporter YPA_3571 ENOG4105S8Q sugar efflux transporter YPA_3573 ENOG4105DP9 ABC transporter YPA_3574 ENOG4106SMU thiamine transporter membrane protein YPA_3576 ENOG4108KF1 Membrane YPA_3577 ENOG4105CQ2 DNA polymerase YPA_3589 ENOG4105CS6 Rhs element vgr protein YPA_3590 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPA_3599 ENOG4105CMM transposase YPA_3602 ENOG4105C12 Phosphoribosylglycinamide synthetase YPA_3603 ENOG4108T8B Protein of unknown function (DUF1481) YPA_3605 ENOG4105R2J Conserved Protein YPA_3606 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) YPA_3611 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) YPA_3613 ENOG4105D06 uba thif-type nad fad binding protein YPA_3616 ENOG4105D41 biosynthesis protein thiH YPA_3617 ENOG4108RS6 transposase YPA_3624 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) YPA_3625 ENOG4105PM1 preprotein translocase subunit SecE YPA_3631 ENOG4107TYG Oxidoreductase domain-containing protein YPA_3632 ENOG4105W4W Transcriptional regulator YPA_3633 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) YPA_3634 ENOG4108RVA ribokinase YPA_3635 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPA_3637 ENOG4105GVF (ABC) transporter YPA_3639 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component YPA_3642 ENOG4105C7N Xanthine uracil vitamin C permease YPA_3643 ENOG4105EEQ Na H antiporter YPA_3645 ENOG4105D1S lipid A biosynthesis YPA_3647 ENOG4105C2J ABC transporter YPA_3648 ENOG4105CNN ABC, transporter YPA_3650 ENOG4105EF1 ribulokinase YPA_3651 ENOG4105C2X Arabinose 5-phosphate isomerase YPA_3652 ENOG4105CYM Glutathione S-transferase YPA_3655 ENOG4108RS6 transposase YPA_3656 ENOG4105VEQ Cold shock protein YPA_3657 ENOG4105VEQ Cold shock protein YPA_3659 ENOG4108XTF Outer Membrane Lipoprotein YPA_3662 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase YPA_3663 ENOG4105CSH Transporter YPA_3666 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) YPA_3667 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) YPA_3669 ENOG4108IA2 Sodium pantothenate symporter YPA_3670 ENOG4105RG0 Membrane YPA_3671 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase YPA_3672 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein YPA_3675 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) YPA_3676 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family YPA_3677 ENOG41062P1 Diguanylate cyclase phosphodiesterase YPA_3678 ENOG4105DFF Rod shape-determining protein mreb YPA_3679 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) YPA_3680 ENOG4105VQ7 Rod shape-determining protein MreD YPA_3682 ENOG4105C03 ribonuclease YPA_3683 ENOG4105QD6 exported protein YPA_3685 ENOG4105D1U peptidase U62 modulator of DNA gyrase YPA_3696 ENOG4105CR8 Transcriptional regulator YPA_3700 ENOG4105C26 Dehydrogenase YPA_3703 ENOG4105UNR (Barnase) inhibitor YPA_3705 ENOG4105CMS peptidase U62, modulator of DNA gyrase YPA_3707 ENOG4108XVM Cytochrome b(562) YPA_3708 ENOG4105NXH GreA GreB family elongation factor YPA_3709 ENOG4105CG3 alpha amylase, catalytic region YPA_3710 ENOG4105C5Y PTS System YPA_3711 ENOG4105D4X repressor YPA_3713 ENOG4105KME endoribonuclease L-psp YPA_3716 ENOG41080Z8 PHOSPHOCARRIER protein YPA_3718 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN YPA_3719 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA YPA_3720 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA YPA_3721 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPA_3722 ENOG4108IUZ ABC transporter YPA_3723 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA YPA_3724 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) YPA_3725 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase YPA_3726 ENOG4105C2X Arabinose 5-phosphate isomerase YPA_3727 ENOG4105FEU K -dependent Na -Ca exchanger YPA_3728 ENOG4105DHJ ABC, transporter YPA_3729 ENOG4105CY3 ABC transporter, permease YPA_3730 ENOG4107PE3 Mammalian cell entry related domain protein YPA_3731 ENOG4105E3I toluene tolerance YPA_3732 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane YPA_3733 ENOG4105VFK BolA family YPA_3735 ENOG4105C0H protease YPA_3736 ENOG4108RS6 transposase YPA_3737 ENOG4105C0H protease YPA_3738 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III YPA_3739 ENOG4105D6Z AFG1 family ATPase YPA_3742 ENOG4107MKT Stringent starvation protein a YPA_3743 ENOG4105KB2 stringent starvation protein b YPA_3745 ENOG4105BZ8 glutamate synthase YPA_3746 ENOG4105CBC glutamate synthase YPA_3747 ENOG4105N5T Radical SAM Protein YPA_3748 ENOG4105BZU Histidine kinase YPA_3749 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain YPA_3751 ENOG4105W4M Transport-associated protein YPA_3755 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) YPA_3756 ENOG4108CNN domain protein YPA_3757 ENOG4105CWB LysR family transcriptional Regulator YPA_3758 ENOG4105CHF Glutathione S-transferase YPA_3762 ENOG4105DQ6 Transposase YPA_3766 ENOG4105C6V Glycerol-3-phosphate dehydrogenase YPA_3767 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) YPA_3772 ENOG4108HRK Histidine kinase YPA_3777 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) YPA_3778 ENOG41076UM multiple antibiotic resistance (MarC)-related protein YPA_3782 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family YPA_3783 ENOG4105C6Z Gluconate YPA_3784 ENOG4105DIQ Transcriptional regulator YPA_3785 ENOG4105C2I pirin domain protein YPA_3786 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPA_3788 ENOG4105D2N Aldolase YPA_3790 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPA_3791 ENOG4105CNN ABC, transporter YPA_3794 ENOG4105CBX hi0933 family YPA_3795 ENOG4105CJ3 phosphate transporter YPA_3796 ENOG4108RS6 transposase YPA_3798 ENOG4108M6U Universal stress protein A YPA_3802 ENOG4105DGW oligopeptidase A YPA_3804 ENOG4105D6S protein involved in catabolism of external DNA YPA_3805 ENOG4105DC8 reductase YPA_3806 ENOG4107VHA regulatoR YPA_3807 ENOG4107QQ0 gntp family YPA_3808 ENOG4105BZW Glycerate kinase YPA_3813 ENOG4107H3J ribonuclease YPA_3814 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) YPA_3815 ENOG41066T0 asmA family YPA_3816 ENOG4105CMB EAL domain-containing protein YPA_3817 ENOG4105VSH 4-oxalocrotonate tautomerase YPA_3818 ENOG4107SS6 2-dehydro-3-deoxygluconokinase YPA_3819 ENOG4105CS0 peptidase YPA_3823 ENOG4108PU9 oligogalacturonate-specific porin YPA_3824 ENOG4105BZU Histidine kinase YPA_3825 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) YPA_3826 ENOG4108JQ7 (ABC) transporter YPA_3827 ENOG4105C3U ABC transporter YPA_3828 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPA_3829 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPA_3830 ENOG4105DEF Extracellular solute-binding protein, family 5 YPA_3831 ENOG4105D5K Hemolysin activator protein YPA_3833 ENOG4108RS6 transposase YPA_3834 ENOG4105CXY transporter YPA_3835 ENOG4105BZU Histidine kinase YPA_3838 ENOG4105C5H ABC transporter YPA_3840 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase YPA_3841 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) YPA_3842 ENOG4105EAC phosphoserine phosphatase YPA_3843 ENOG41062Z9 Membrane YPA_3848 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPA_3849 ENOG4105D9N nucleoside YPA_3850 ENOG4105EYA deoxyribonuclease YPA_3851 ENOG4108NRW Phospholipase, patatin family YPA_3853 ENOG4105K3G Periplasmic Protein YPA_3855 ENOG4105KEG ribosomal-protein-alanine acetyltransferase YPA_3856 ENOG4108WPU DNA polymerase III subunit psi YPA_3859 ENOG4105YBH Protein of unknown function (DUF1435) YPA_3860 ENOG4105BZU Histidine kinase YPA_3864 ENOG4105BZS acriflavin resistance protein YPA_3865 ENOG410624X efflux transporter, rnd family, mfp subunit YPA_3868 ENOG4105DKP glycosyl transferase, family 9 YPA_3870 ENOG4105DKT Transcriptional regulator YPA_3871 ENOG4105DKT Transcriptional regulator YPA_3879 ENOG4105RI1 glycoprotein receptor YPA_3880 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) YPA_3881 ENOG4105DM4 PTS System YPA_3882 ENOG4108YRF PTS System YPA_3883 ENOG4108XCZ PTS System YPA_3884 ENOG4106R3P AraC family transcriptional regulator YPA_3886 ENOG4108M3P Membrane YPA_3897 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 YPA_3901 ENOG4105WSB biofilm stress and motility protein A YPA_3902 ENOG4105CSU acyl-Coa dehydrogenase YPA_3903 ENOG4105C2N RNA methyltransferase TrmH family group 3 YPA_3904 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) YPA_3908 ENOG4105EPW hflc protein YPA_3909 ENOG4107QJR hflk protein YPA_3910 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) YPA_3914 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase YPA_3915 ENOG4105K8N protein family UPF0079, ATPase YPA_3916 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) YPA_3917 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) YPA_3918 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) YPA_3921 ENOG4105EGS Mechanosensitive ion channel YPA_3926 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) YPA_3927 ENOG4105KPY Small multidrug resistance protein YPA_3929 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein YPA_3930 ENOG4108ZVF (LipO)protein YPA_3935 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPA_3938 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) YPA_3939 ENOG4108RC0 Electron transport protein YPA_3940 ENOG4105BZ8 glutamate synthase YPA_3941 ENOG4108SIC Transcriptional regulator YPA_3955 ENOG4105C0A alcohol dehydrogenase YPA_3958 ENOG4105C0A alcohol dehydrogenase YPA_3960 ENOG4108UUM single-stranded DNA-binding protein YPA_3961 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) YPA_3962 ENOG4105MSB protein, conserved in bacteria YPA_3963 ENOG4105CGF Aromatic amino acid aminotransferase YPA_3964 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) YPA_3965 ENOG4105CDU Replicative dna helicase YPA_3966 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein YPA_3967 ENOG4105P4Z Phage shock protein G YPA_3968 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) YPA_3969 ENOG4105MYN Zinc uptake regulation protein YPA_3971 ENOG41080IJ Diacylglycerol kinase YPA_3979 ENOG4108S1B Periplasmic chaperone protein YPA_3991 ENOG4105DAX Pfam:DUF2983 YPA_3995 ENOG4105D4P Coproporphyrinogen iii oxidase YPA_3996 ENOG41090JE Utilization Protein YPA_3998 ENOG4107F3C Hemin uptake protein YPA_3999 ENOG4107ENK receptor YPA_4000 ENOG4106QJH hemin transport protein YPA_4001 ENOG4107R4I Periplasmic binding protein YPA_4002 ENOG4105EHG Permease protein YPA_4004 ENOG4105C28 cystathionine YPA_4005 ENOG4105C44 Serine transporter YPA_4006 ENOG4105EQ2 LysR family Transcriptional regulator YPA_4007 ENOG4105KSU Redox protein YPA_4008 ENOG41066VF YeeE YedE family protein YPA_4009 ENOG4108IUF type iii secretion YPA_4010 ENOG4108TN6 type iii secretion YPA_4011 ENOG41083GP type iii secretion YPA_4012 ENOG4108HHI Type III secretion system protein YPA_4013 ENOG41063Q7 Type III secretion system protein YPA_4016 ENOG4108JIR Flagellum-specific ATP synthase YPA_4028 ENOG4105BZU Histidine kinase YPA_4029 ENOG4105WH1 Two component transcriptional regulator luxr family YPA_4030 ENOG4105CK2 sodium dicarboxylate symporter YPA_4032 ENOG41062QD Membrane YPA_4037 ENOG4105C5H ABC transporter YPA_4038 ENOG4105C5H ABC transporter YPA_4039 ENOG41090EK ompa motb domain protein YPA_4040 ENOG4108KHX Diguanylate cyclase YPA_4043 ENOG4107SC1 transglycosylase YPA_4044 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) YPA_4047 ENOG4105UEI Transcriptional Regulator AraC Family YPA_4048 ENOG4108RH0 Crea protein YPA_4049 ENOG41065U4 response regulator YPA_4058 ENOG4108RIR Molybdenum cofactor biosynthesis protein YPA_4061 ENOG4106HK8 GPR1 FUN34 yaaH family protein YPA_4065 ENOG41063Z6 transcriptional regulator, lysR family YPA_4067 ENOG4105DTN riboflavin biosynthesis protein ribF YPA_4070 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase YPA_4072 ENOG4108RS6 transposase YPA_4074 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain YPA_4075 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain YPA_4076 ENOG4105N14 lysine exporter protein LysE YggA YPA_4077 ENOG4105DWK Membrane YPA_4079 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) YPA_4080 ENOG4108RS6 transposase YPA_4087 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) YPA_4090 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) YPA_4091 ENOG4105D3G Pseudouridine synthase YPA_4099 ENOG4105BZU Histidine kinase YPA_4100 ENOG4108KX4 response regulator YPA_4101 ENOG4105DIJ Phosphoethanolamine transferase YPA_4103 ENOG4105C85 amino acid YPA_4104 ENOG4105C84 Histidine ammonia-lyase YPA_4106 ENOG4105C6T cysteine synthase YPA_4115 ENOG4105CM4 permease protein YPA_4116 ENOG4108IPW abc transporter atp-binding protein YPA_4123 ENOG4105DFP Integrase YPA_4124 ENOG4105T16 Transcriptional regulator (AraC family) YPA_4125 ENOG4107RNG ABC transporter YPA_4127 ENOG4105DFW ABC transporter YPA_4129 ENOG4105CMG Carbohydrate kinase YPA_4131 ENOG4108TTM chaperone YPA_4135 ENOG4106EAR Fimbrial protein YPA_4136 ENOG4105MEV Acyl-transferase YPA_4138 ENOG4105DQ6 Transposase YPA_4139 ENOG410667J hydrolase YPA_4140 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPA_4141 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) YPA_4142 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) YPA_4144 ENOG4105VG0 50S ribosomal protein l34 YPA_4147 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins YPA_4152 ENOG4105C7N Xanthine uracil vitamin C permease YPA_4153 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 YPA_4154 ENOG4105DRP amino acid AbC transporter YPA_4155 ENOG4105EAD ABC transporter YPA_4156 ENOG4106PMH Extracellular solute-binding protein family 3 YPA_4160 ENOG4105E2Z phosphate ABC transporter (Permease YPA_4161 ENOG4105C8U phosphate abc transporter YPA_4162 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) YPA_4163 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) YPA_4171 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) YPA_4173 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YPA_CD0048 ENOG4105EZN Cobyrinic acid ac-diamide synthase YPA_CD0049 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB YPA_CD0053 ENOG4105CMM transposase YPA_CD0057 ENOG4105CMM transposase YPA_CD0059 ENOG4108C33 Resolvase YPA_CD0061 ENOG4105D13 transposase YPA_CD0068 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) YPA_CD0069 ENOG4106CQM replication YPA_CD0073 ENOG4105CMM transposase YPA_CD0074 ENOG4105E5H Transposase YPA_CD0077 ENOG4105CMM transposase YPA_MT0003 ENOG4105UZW Tail fiber assembly protein YPA_MT0004 ENOG4108X9F tail fiber protein YPA_MT0004 ENOG4108X9F tail fiber protein YPA_MT0012 ENOG4108NYK Tape measure protein YPA_MT0031 ENOG4105FA0 parb-like partition protein YPA_MT0032 ENOG4105FA0 parb-like partition protein YPA_MT0033 ENOG4105CB5 ATP-dependent DNA helicase recG YPA_MT0038 ENOG4108RS6 transposase YPA_MT0044 ENOG4106JVB Replication Protein YPA_MT0052 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) YPA_MT0054 ENOG4105C2M dna polymerase I YPA_MT0059 ENOG4106J5W DNA polymerase III (alpha subunit) YPA_MT0069 ENOG4108D1K outer membrane usher protein YPA_MT0070 ENOG4108UIF Chaperone YPA_MT0072 ENOG4105EQR Transposase IS116 IS110 IS902 YPA_MT0074 ENOG4105EKQ RNA-directed DNA polymerase YPA_MT0082 ENOG4106RMF ParB family YPA_MT0086 ENOG41073YN Protein of unknown function (DUF1380) YPA_MT0090 ENOG4105FEQ ParB domain protein nuclease YPA_MT0096 ENOG4106PHM regulatory protein YPA_PCP0007 ENOG4105XUP Phage derived protein Gp49-like (DUF891)