locus-tag class description AK38_10 ENOG4107Z6W Protein CrcB homolog AK38_100 ENOG4105CPQ Dehydrogenase AK38_1000 ENOG4105CNN ABC, transporter AK38_1002 ENOG4107SRH Nad-dependent epimerase dehydratase AK38_1004 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AK38_1006 ENOG4105ECC imidazole-glycerol-phosphate dehydratase AK38_101 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_1010 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AK38_1011 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AK38_1012 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AK38_1013 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AK38_1014 ENOG4105DUU IucA IucC family protein AK38_1015 ENOG4105CNM Receptor AK38_1016 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) AK38_1017 ENOG4105DQ5 transport system permease protein AK38_1018 ENOG4105TVJ transport system, permease AK38_1019 ENOG4105E0A ABC, transporter AK38_102 ENOG4105C2J ABC transporter AK38_1020 ENOG4105DUU IucA IucC family protein AK38_1022 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) AK38_1023 ENOG4105DY8 decarboxylase AK38_1024 ENOG4108819 ferric iron reductase AK38_1025 ENOG4105EE5 Membrane protein terC AK38_1026 ENOG4108GAE asmA family AK38_1029 ENOG4105D1F ATP-binding protein AK38_103 ENOG4105CNN ABC, transporter AK38_1031 ENOG4108RS6 transposase AK38_1037 ENOG4105E5W Transporter AK38_1039 ENOG41067MG lrgb family AK38_104 ENOG4105FKQ transcriptional regulator AK38_1042 ENOG4107GZ4 SanA protein AK38_1043 ENOG4108HWV )-transporter AK38_1046 ENOG4105DHF Membrane AK38_1048 ENOG4105CBP Major Facilitator AK38_1049 ENOG4105EGI Transcriptional regulator AK38_105 ENOG4105EJC lysr family transcriptional regulator AK38_1054 ENOG4105ENT Efflux transporter rnd family, mfp subunit AK38_1055 ENOG4105C19 ABC transporter AK38_1057 ENOG4105CVM Molybdenum cofactor synthesis domain protein AK38_1058 ENOG4105D06 uba thif-type nad fad binding protein AK38_106 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AK38_1061 ENOG4105C5H ABC transporter AK38_107 ENOG4105C94 Transporter AK38_108 ENOG4105DVW rieske (2Fe-2S) AK38_1080 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_1082 ENOG4105CDV Ompa motb domain protein AK38_1088 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AK38_1089 ENOG41062T2 Acyl carrier protein AK38_109 ENOG4105E3J oxidoreductase AK38_1091 ENOG4105CHR reductase AK38_1092 ENOG4108KQ6 Enoyl-CoA hydratase AK38_1094 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase AK38_1095 ENOG4105CHR reductase AK38_1096 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_1097 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) AK38_110 ENOG4105D5K Hemolysin activator protein AK38_1104 ENOG4108BUD transposase AK38_1106 ENOG4108Z0T Part of a sulfur-relay system (By similarity) AK38_111 ENOG4105CKT filamentous hemagglutinin AK38_1110 ENOG4105K4P CoA-binding domain protein AK38_1113 ENOG41088T4 Helicase IV AK38_1114 ENOG410901E Membrane AK38_1115 ENOG4105EM2 membrane AK38_1116 ENOG4108RZ1 DNA transformation protein AK38_1119 ENOG4108RS6 transposase AK38_1121 ENOG4105DAN ATP-dependent protease AK38_1124 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_1128 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_1129 ENOG4108RS6 transposase AK38_1130 ENOG4108Q2G (LipO)protein AK38_1131 ENOG4105DY2 Paraquat-inducible protein b AK38_1132 ENOG4105F1S paraquat-inducible protein a AK38_1133 ENOG4105C5H ABC transporter AK38_1135 ENOG4105QVC MOSC domain-containing protein AK38_1136 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) AK38_1138 ENOG4105CD8 aminopeptidase N AK38_114 ENOG4105CKT filamentous hemagglutinin AK38_1142 ENOG4105CGF Aromatic amino acid aminotransferase AK38_1143 ENOG4105C5X domain protein AK38_1144 ENOG4105EAQ (twin-arginine translocation) pathway signal AK38_1145 ENOG4105DIT ErfK YbiS YcfS YnhG family protein AK38_1146 ENOG4108RS6 transposase AK38_1150 ENOG4106371 Methyltransferase AK38_1151 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups AK38_1154 ENOG4105VEQ Cold shock protein AK38_1155 ENOG4105E32 cytoplasmic protein AK38_1158 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 AK38_1161 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AK38_1167 ENOG4105HDK L-asparaginase AK38_1168 ENOG4105DDY UPF0142 protein ycaO AK38_1169 ENOG4105TMB Formate nitrite transporter AK38_117 ENOG4105CKT filamentous hemagglutinin AK38_1170 ENOG4105C6N Formate acetyltransferase AK38_1172 ENOG4105F1A Pyruvate formate-lyase AK38_1175 ENOG4105D1H recombination factor protein RarA AK38_1178 ENOG4105CNU cell division protein FtsK AK38_1179 ENOG4105EW9 transcriptional regulator AsnC family AK38_1180 ENOG4105C3M thioredoxin reductase AK38_1181 ENOG4108JJ9 ABC, transporter AK38_1182 ENOG4108JJ8 (ABC) transporter AK38_1185 ENOG4108RS6 transposase AK38_1186 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_1188 ENOG4105VEQ Cold shock protein AK38_119 ENOG4108IJ9 (ABC) transporter AK38_1190 ENOG4105DJY efflux transporter, rnd family, mfp subunit AK38_1191 ENOG4108MJ5 VirK protein AK38_1192 ENOG4105CPB ATP-dependent endonuclease of the OLD family AK38_1193 ENOG4105DWU Membrane AK38_1195 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AK38_1196 ENOG4105C7K acetolactate synthase AK38_1197 ENOG4105C5W Aldolase AK38_1198 ENOG4105CGD Nad-dependent epimerase dehydratase AK38_1199 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AK38_1200 ENOG41064MM (LipO)protein AK38_1201 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) AK38_1202 ENOG4105E5Z arginine transporter ATP-binding subunit AK38_1203 ENOG4106PMH Extracellular solute-binding protein family 3 AK38_1204 ENOG4105GBT ABC transporter AK38_1205 ENOG4105DMR ABC, transporter AK38_1206 ENOG4108I0N Transporter, RarD family, DMT superfamily protein AK38_1207 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) AK38_1208 ENOG410642S Nicotianamine synthase protein AK38_1209 ENOG4105E0A ABC, transporter AK38_121 ENOG4105ETE Transcriptional regulator (LacI family AK38_1210 ENOG4105DQ5 transport system permease protein AK38_1215 ENOG4106TNF Periplasmic binding protein AK38_1218 ENOG4106TNF Periplasmic binding protein AK38_1220 ENOG4105RBQ inner membrane protein ybjO AK38_1221 ENOG4105D38 putrescine abc transporter AK38_1222 ENOG4105F38 ABC transporter, permease AK38_1223 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AK38_1224 ENOG4107RUE extracellular solute-binding protein family 1 AK38_1225 ENOG4108RMJ sensory transduction regulator AK38_1226 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress AK38_1227 ENOG41090BQ Glutaredoxin AK38_1230 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AK38_1232 ENOG4107FB0 transcriptional regulator DeoR family AK38_1233 ENOG4105C44 Serine transporter AK38_1234 ENOG4105DZ1 carboxypeptidase AK38_1235 ENOG4108UMI ABC transporter, permease AK38_1237 ENOG4105D01 (LipO)protein AK38_124 ENOG4105DRS transport system, permease AK38_1240 ENOG4108TGY Glutathione S-transferase AK38_1241 ENOG4105D05 Receptor AK38_1243 ENOG4105EHG Permease protein AK38_1245 ENOG4108IQI permease AK38_1247 ENOG4105DUM transcriptional regulator, lysR family AK38_1248 ENOG4105HMI Membrane AK38_125 ENOG4105HY2 Glycosidase related protein AK38_1250 ENOG4108D1K outer membrane usher protein AK38_1251 ENOG4108UIF Chaperone AK38_1254 ENOG4108SGD regulatory protein AK38_1255 ENOG4105DM4 PTS System AK38_1256 ENOG4105DE4 1-phosphofructokinase AK38_1257 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein AK38_1259 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AK38_1260 ENOG4105C2J ABC transporter AK38_1264 ENOG4105C26 Dehydrogenase AK38_1267 ENOG4105CHR reductase AK38_1268 ENOG4105KRS Proteinase inhibitor AK38_1272 ENOG4105DEI Mannitol dehydrogenase AK38_1273 ENOG4107YCY Transcriptional regulator AK38_1275 ENOG4105CKI cobalamin synthesis protein AK38_1276 ENOG41076MN Phosphoesterase, PA-phosphatase related AK38_1277 ENOG4107TT5 NLP P60 protein AK38_1279 ENOG4105CXC rtn protein AK38_1280 ENOG4105E43 Extracellular solute-binding protein, family 5 AK38_1281 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component AK38_1282 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component AK38_1283 ENOG4108JQ5 ABC transporter AK38_1284 ENOG4105HG6 AK38_1285 ENOG4105C2C drug resistance transporter, Bcr CflA AK38_1286 ENOG4105I08 Pseudouridine synthase AK38_1287 ENOG4105CFI type iii restriction protein res subunit AK38_1289 ENOG4108RS6 transposase AK38_129 ENOG4105CUY Mechanosensitive ion channel AK38_1291 ENOG4105PAN UPF0352 protein AK38_1292 ENOG4105E68 Sulfatase AK38_1295 ENOG4105GMB type VI secretion system effector, hcp1 family AK38_1299 ENOG4105CS2 ec 3.2.1.21 AK38_13 ENOG4108N8T regulatoR AK38_130 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) AK38_1301 ENOG4108Q3X Transcriptional regulator AK38_1305 ENOG4108T86 baseplate J family protein AK38_131 ENOG4107IIZ CRISPR-associated helicase, Cas3 AK38_1313 ENOG4105TKZ Tail Sheath AK38_1317 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) AK38_1318 ENOG4105MVE transcriptional regulator AK38_132 ENOG4105ENG CRISPR-associated protein, Csy1 family AK38_1320 ENOG4105G63 Type III effector Hrp-dependent AK38_1321 ENOG4105HRS Antitermination protein AK38_1323 ENOG4105Y50 Virulence Protein AK38_1325 ENOG4105C8Q Methyl-accepting chemotaxis AK38_1327 ENOG4105CT4 transporter AK38_1328 ENOG4107R6D beta-lactam binding protein AmpH AK38_133 ENOG4105DZX CRISPR-associated protein, Csy2 family AK38_1331 ENOG4108RS6 transposase AK38_1332 ENOG4108RS6 transposase AK38_1333 ENOG4105FCK Membrane AK38_1335 ENOG4106UW1 Major Facilitator superfamily AK38_1336 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC AK38_1337 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC AK38_1338 ENOG41068CG regulatoR AK38_1339 ENOG4105BZU Histidine kinase AK38_134 ENOG4105M6W Crispr-associated protein, Csy3 family AK38_1340 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_1342 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AK38_1343 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AK38_1344 ENOG4105XPH Ferredoxin AK38_1347 ENOG4105E0U tyrosine-specific transport protein AK38_1348 ENOG4108UII YfaZ family AK38_1349 ENOG4105CH6 catalase AK38_135 ENOG4108Y1S CRISPR-associated protein, Csy4 family AK38_1350 ENOG4105DVT helicase AK38_1352 ENOG4105FDR Membrane AK38_1354 ENOG4105CXN decarboxylase AK38_1355 ENOG4105D5Q Arginine ornithine antiporter AK38_1356 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component AK38_1357 ENOG4108IJ8 ABC transporter AK38_1358 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component AK38_136 ENOG4105CPC Aldo Keto reductase AK38_1361 ENOG4105KHC sulfurtransferase AK38_1364 ENOG4108IV0 ABC, transporter AK38_1365 ENOG4108JJB ABC transporter AK38_1366 ENOG4105CNN ABC, transporter AK38_1367 ENOG4105C32 Amino acid ABC transporter (Permease) AK38_1369 ENOG4108W15 Protein of unknown function (DUF1456) AK38_1372 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein AK38_1374 ENOG4105Y3U Transglycosylase-associated protein AK38_1376 ENOG4105N1F Hnh endonuclease AK38_1378 ENOG4105CXG d-lactate dehydrogenase AK38_1379 ENOG41061WM D-Alanyl-D-Alanine AK38_138 ENOG4105C54 Major Facilitator superfamily AK38_1381 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) AK38_1383 ENOG4108RS6 transposase AK38_1384 ENOG4105EAA nucleoside AK38_1385 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) AK38_1387 ENOG4105CN8 Transcriptional regulator AK38_1388 ENOG4105C94 Transporter AK38_1392 ENOG4108RS6 transposase AK38_1393 ENOG4105HFZ Membrane AK38_1394 ENOG4108ZAF Molybdopterin AK38_1395 ENOG4105M00 molybdopterin converting factor, subunit 1 AK38_1397 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AK38_1399 ENOG4105CHW UPF0052 protein AK38_140 ENOG4105ETT transcriptional Regulator, LysR family AK38_1400 ENOG4105VYA Uncharacterized conserved protein (DUF2132) AK38_1404 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AK38_1409 ENOG4108K4B hydrolase AK38_141 ENOG4107YC3 synthase AK38_1411 ENOG4105E0C molybdate abc transporter AK38_1412 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AK38_1414 ENOG4105F4R Transcriptional regulator mode AK38_1415 ENOG4105DKW ABC transporter AK38_1418 ENOG4105CMR udp-glucose 4-epimerase AK38_1419 ENOG4105F0Z galactose-1-phosphate uridylyltransferase AK38_142 ENOG4105VJY transcriptional regulator AK38_1422 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) AK38_1427 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AK38_1429 ENOG4105PGM cation diffusion facilitator family transporter AK38_1430 ENOG4106Z1T Nicotinamide Mononucleotide Transporter AK38_1435 ENOG4105UFD tol-pal system protein YbgF AK38_1436 ENOG4105KCK Peptidoglycan-associated lipoprotein AK38_1438 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA AK38_1438 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA AK38_1440 ENOG4105E02 MotA TolQ exbB proton channel AK38_1441 ENOG4107YD3 Thioesterase AK38_1442 ENOG4105KJB cyd operon protein YbgE AK38_1444 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AK38_1445 ENOG4105C4M (Ubiquinol oxidase) subunit I AK38_1446 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AK38_1448 ENOG4105C7S Dehydrogenase AK38_1449 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 AK38_1450 ENOG4105E33 succinate dehydrogenase AK38_1452 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein AK38_1453 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit AK38_1454 ENOG4105BZN citrate synthase AK38_1456 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AK38_1457 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AK38_1458 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AK38_146 ENOG4105DSF transport protein AK38_1460 ENOG4108Z1B Cyclase dehydrase AK38_1462 ENOG4108RS6 transposase AK38_1463 ENOG4105DFP Integrase AK38_1473 ENOG4105VUH addiction module killer protein AK38_1480 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease AK38_1482 ENOG4107RZZ dna polymerase iii epsilon subunit AK38_1484 ENOG4105D1A Methyltransferase AK38_1485 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AK38_1486 ENOG4105E9H Lytic Murein transglycosylase AK38_1489 ENOG4105CV8 reductase AK38_1495 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase AK38_1497 ENOG4108UMI ABC transporter, permease AK38_1498 ENOG4105D01 (LipO)protein AK38_1499 ENOG4108R8X outer membrane lipoprotein AK38_150 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 AK38_1500 ENOG4108R96 Methyltransferase, YaeB family AK38_1502 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion AK38_1503 ENOG4108YZN class I peptide chain release factor AK38_1504 ENOG4108VWS Yaeq family AK38_1506 ENOG4105M1T rho-binding antiterminator AK38_1508 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AK38_1509 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase AK38_151 ENOG4107PN8 YfeABCD locus regulator AK38_1511 ENOG4105C0B DNA polymerase III (alpha subunit) AK38_1516 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AK38_1519 ENOG4105DZP Membrane-associated zinc metalloprotease AK38_1520 ENOG4105KNE Phosphatidate cytidylyltransferase AK38_1527 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AK38_153 ENOG4105CC5 ABC transporter AK38_1531 ENOG4105QDK Flavodoxin AK38_1532 ENOG4105DR9 pseudouridine synthase AK38_1533 ENOG4105WP7 tRNA pseudouridine synthase C AK38_1534 ENOG4108RS6 transposase AK38_1537 ENOG4105EWT decarboxylase family AK38_154 ENOG4105CC5 ABC transporter AK38_1540 ENOG4105M08 Membrane AK38_1541 ENOG4105ETT transcriptional Regulator, LysR family AK38_1543 ENOG4105C9B Cysteine desulfurase AK38_1544 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) AK38_1545 ENOG4105CUZ uba thif-type nad fad binding protein AK38_1546 ENOG4105CA3 membrane-bound lytic murein transglycosylase AK38_1549 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AK38_155 ENOG4105DIK (ABC) transporter AK38_1551 ENOG4107QYX exodeoxyribonuclease v alpha AK38_1552 ENOG4107QKA exodeoxyribonuclease V beta AK38_1553 ENOG4107QXK peptidase AK38_1554 ENOG4105DSY exodeoxyribonuclease V, gamma AK38_156 ENOG4105DSE periplasmic solute binding protein AK38_1561 ENOG4107ZSV Receptor AK38_1562 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AK38_1563 ENOG4105CFC Transporter AK38_1571 ENOG4105C1P efflux transporter, rnd family, mfp subunit AK38_1574 ENOG4105DQ6 Transposase AK38_1576 ENOG4105CT4 transporter AK38_1578 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) AK38_1579 ENOG4105DUU IucA IucC family protein AK38_1598 ENOG4105CDV Ompa motb domain protein AK38_160 ENOG41087WU AK38_1600 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_1612 ENOG4105CXN decarboxylase AK38_1613 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_1614 ENOG4105C2J ABC transporter AK38_1615 ENOG4105CNN ABC, transporter AK38_1620 ENOG4105CEN a g-specific adenine glycosylase AK38_1622 ENOG41090ED Protein with unknown function (DUF469) AK38_1624 ENOG4105K33 Periplasmic Protein AK38_1625 ENOG4105K33 Periplasmic Protein AK38_1626 ENOG4105EUK rtx toxin RtxA AK38_1627 ENOG4105CSA Coproporphyrinogen iii oxidase AK38_1628 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AK38_1630 ENOG4108VIA integral membrane protein AK38_1631 ENOG4105II7 pyrroline-5-carboxylate reductase AK38_1632 ENOG4105DFA alanine racemase domain protein AK38_1633 ENOG4105CZX twitching motility protein AK38_1635 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) AK38_1638 ENOG4105D7Z glutathione synthase AK38_1639 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AK38_1640 ENOG4105RWS endonuclease I AK38_1641 ENOG4105GPY SprT protein AK38_1644 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) AK38_1646 ENOG4108K0D peptidase, M48 AK38_1647 ENOG4105CV1 Transketolase (EC 2.2.1.1) AK38_1648 ENOG4108RS6 transposase AK38_1653 ENOG4105D2N Aldolase AK38_1654 ENOG4105D64 Mechanosensitive ion channel AK38_1656 ENOG4105MPN Membrane AK38_1659 ENOG4108JQ1 Dehydrogenase AK38_166 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AK38_1660 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AK38_1663 ENOG4107RAQ aminopeptidase AK38_1664 ENOG4105D0A hydroxylase AK38_1665 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AK38_167 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AK38_1673 ENOG4108UT2 hemolysin iii AK38_1677 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_1678 ENOG4105EB3 Histidine kinase AK38_1679 ENOG4105CT7 inner membrane cred family protein AK38_1680 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) AK38_1681 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AK38_1682 ENOG4105T95 Thiol disulfide interChange protein AK38_1683 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AK38_1687 ENOG4105DFP Integrase AK38_1691 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation AK38_1692 ENOG4105WJ3 XRE family Transcriptional regulator AK38_170 ENOG4108V06 Glutathione peroxidase AK38_1709 ENOG4105NTW Transcriptional regulator AK38_1710 ENOG4108UY0 (LipO)protein AK38_1712 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_1713 ENOG4105CNN ABC, transporter AK38_1716 ENOG4107FKK extracellular solute-binding protein family 1 AK38_1718 ENOG4105EG2 ABC transporter, permease AK38_1720 ENOG4105C4C beta-galactosidase AK38_1721 ENOG4105CI1 PTS System AK38_1723 ENOG4105ETE Transcriptional regulator (LacI family AK38_1725 ENOG4105DPW Major facilitator superfamily MFS_1 AK38_1726 ENOG4105ETE Transcriptional regulator (LacI family AK38_1729 ENOG4105D2N Aldolase AK38_1731 ENOG4105ENH Sulfatase AK38_1732 ENOG4105C4X radical SAM domain protein AK38_1734 ENOG4105CHR reductase AK38_1735 ENOG4105CE4 GlcNAc 6-P deacetylase AK38_1736 ENOG4108YTN IIa component AK38_1737 ENOG4105F3R pts system mannose fructose sorbose family iid AK38_1738 ENOG4105ETZ PTS System AK38_1739 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB AK38_1740 ENOG4105E70 isomerase AK38_1741 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of AK38_1742 ENOG4105E98 transcriptional regulator DeoR family AK38_1743 ENOG4105CBG Sulfatase AK38_1744 ENOG4108RS6 transposase AK38_1752 ENOG4107B2H carbonic anhydrase AK38_1756 ENOG4107QHF type ii secretion system protein e AK38_1758 ENOG4105D7Q type ii secretion system AK38_1771 ENOG4105C8Q Methyl-accepting chemotaxis AK38_1773 ENOG4105EJC lysr family transcriptional regulator AK38_1774 ENOG4105RQF LysR family Transcriptional regulator AK38_1775 ENOG4105F27 Major Facilitator AK38_1776 ENOG41060NJ transcriptional regulator AK38_1783 ENOG4105CPC Aldo Keto reductase AK38_1786 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase AK38_179 ENOG4108QBX (LipO)protein AK38_1794 ENOG4105C0W non-ribosomal peptide synthetase AK38_1796 ENOG4105C0W non-ribosomal peptide synthetase AK38_18 ENOG4108JJ7 ABC transporter AK38_1802 ENOG4105BZ1 (ABC) transporter AK38_1806 ENOG4107EFN gluconate transport system permease 3 AK38_1809 ENOG4105CS6 Rhs element vgr protein AK38_1811 ENOG4105CNA YD repeat protein AK38_1813 ENOG41062WK cellular response to acidity AK38_1814 ENOG4105C8P )-transporter AK38_1815 ENOG4105ETE Transcriptional regulator (LacI family AK38_1816 ENOG4105DQ6 Transposase AK38_1818 ENOG4108XTF Outer Membrane Lipoprotein AK38_1819 ENOG4108XTF Outer Membrane Lipoprotein AK38_1824 ENOG4107RD7 Flagellar Motor Protein, MotA AK38_183 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AK38_1830 ENOG410804A Flagellar hook-associated 2 domain-containing protein AK38_1834 ENOG4108M3R transcriptional activator CadC AK38_1838 ENOG4105E1Q flagellar hook-associated protein AK38_1840 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) AK38_1842 ENOG4105CGA flagellar basal-body rod protein FlgG AK38_1843 ENOG4108KPB Flagellar basal-body rod protein FlgF AK38_1844 ENOG4108RS6 transposase AK38_1846 ENOG4105BZE flagellar hook protein, FlgE AK38_1847 ENOG4105W00 Flagellar hook capping protein AK38_1848 ENOG4108ZC9 flagellar basal-body rod protein flgc AK38_1849 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AK38_185 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) AK38_1850 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA AK38_1854 ENOG4108JIR Flagellum-specific ATP synthase AK38_1857 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AK38_1858 ENOG4105VQ0 flagellar hook-basal body complex protein fliE AK38_186 ENOG4105IPI Membrane AK38_1861 ENOG4105DD5 Flagellar motor switch protein AK38_1862 ENOG4105CN7 Flagellar biosynthetic protein FliP AK38_1863 ENOG4105VS8 Flagellar biosynthetic protein fliq AK38_1864 ENOG4105D19 Role in flagellar biosynthesis (By similarity) AK38_1865 ENOG4105D00 flagellar biosynthetic protein flhB AK38_187 ENOG4105CQB FAD linked oxidase domain protein AK38_1870 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein AK38_1872 ENOG4106P2F Pfam:Pili_assembly_C AK38_1873 ENOG4106PG1 outer membrane usher protein AK38_1874 ENOG4108RS6 transposase AK38_1875 ENOG4108RS6 transposase AK38_188 ENOG4105KA0 thioesterase Superfamily protein AK38_1889 ENOG4108ZZF transport protein (ExbD) AK38_189 ENOG4108Z4V iron-sulfur cluster assembly AK38_1891 ENOG4105CWK Biopolymer transport protein, ExbB AK38_1892 ENOG4105C28 cystathionine AK38_1893 ENOG4108K81 inner membrane protein YghB AK38_1894 ENOG4105CF7 AraC family transcriptional regulator AK38_1895 ENOG4108I6A alcohol dehydrogenase AK38_1896 ENOG4105CV8 reductase AK38_1899 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) AK38_190 ENOG4105DIW FeS assembly protein SUFB AK38_1900 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase AK38_1901 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_1902 ENOG4105NF4 modulator of drug activity AK38_1903 ENOG4105CR8 Transcriptional regulator AK38_1904 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_1905 ENOG4105IPS esterase AK38_1906 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AK38_1907 ENOG4108SX3 cytoplasmic protein AK38_1908 ENOG41087AY ADP-Ribose pyrophosphatase AK38_1909 ENOG4105DFG type I secretion outer membrane protein AK38_191 ENOG4105C3K feS assembly ATPase SufC AK38_1912 ENOG4106032 Glutathionylspermidine synthase AK38_1913 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AK38_1916 ENOG4105W0Z cytoplasmic protein AK38_1917 ENOG4105DVH amino acid AK38_192 ENOG4105JRK feS assembly protein SufD AK38_1920 ENOG4105I7R Adenylate cyclase AK38_1921 ENOG4106MWK domain protein AK38_1924 ENOG4107ZVW dihydroneopterin aldolase AK38_1928 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AK38_1929 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_1946 ENOG4105KME endoribonuclease L-psp AK38_195 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AK38_1953 ENOG4105J12 Multidrug resistance protein mdtN AK38_1954 ENOG4108MI0 Resistance protein AK38_1956 ENOG4107QK4 glycoside hydrolase, family 3 domain protein AK38_1958 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component AK38_1961 ENOG4107KJX Transcriptional regulator AK38_1962 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 AK38_1967 ENOG4105CKT filamentous hemagglutinin AK38_1971 ENOG4105CKT filamentous hemagglutinin AK38_1972 ENOG4105D5K Hemolysin activator protein AK38_1973 ENOG4108M24 von Willebrand factor, type A AK38_1976 ENOG4108M24 von Willebrand factor, type A AK38_1979 ENOG4108YK4 Acid-resistance membrane protein AK38_1980 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AK38_1983 ENOG4108VKG metal-dependent hydrolase AK38_1984 ENOG4105EE0 oxidoreductase AK38_1987 ENOG4108RS6 transposase AK38_1988 ENOG4105P66 Membrane AK38_1989 ENOG4105CTX dehydratase AK38_1992 ENOG4105DPW Major facilitator superfamily MFS_1 AK38_1995 ENOG4106W5V Membrane AK38_1998 ENOG4105NE1 Conserved Protein AK38_1999 ENOG41090KG Inner membrane protein YqjE AK38_2 ENOG4105CJN penicillin-binding protein AK38_20 ENOG4105DH8 myo-inositol catabolism AK38_2001 ENOG4108VBZ doxx family AK38_2002 ENOG4105CHF Glutathione S-transferase AK38_2005 ENOG4105M6F mutator MutT protein AK38_201 ENOG4108RS6 transposase AK38_2010 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AK38_2011 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AK38_2012 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) AK38_2016 ENOG4105CNI cell division protein FtsW AK38_2019 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) AK38_2020 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AK38_2021 ENOG4105CJN penicillin-binding protein AK38_2022 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AK38_2025 ENOG4108RNS Exports L-alanine (By similarity) AK38_2026 ENOG4107B7Y DNA-binding transcriptional regulator FruR AK38_2027 ENOG4108RS6 transposase AK38_2028 ENOG4108ZP8 Acetolactate synthase small subunit AK38_2029 ENOG4105C7K acetolactate synthase AK38_203 ENOG4105CA9 Pyruvate kinase AK38_2030 ENOG4108IQE Amp-dependent synthetase and ligase AK38_2031 ENOG41064T2 transcriptional regulator, lysR family AK38_2033 ENOG4108RS6 transposase AK38_2035 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AK38_2038 ENOG4105S8Q sugar efflux transporter AK38_2041 ENOG4105S8Q sugar efflux transporter AK38_2044 ENOG4105DP9 ABC transporter AK38_2045 ENOG4106SMU thiamine transporter membrane protein AK38_2046 ENOG4107T0D ABC, transporter AK38_2047 ENOG4108KF1 Membrane AK38_2048 ENOG4105CQ2 DNA polymerase AK38_2060 ENOG4105CS6 Rhs element vgr protein AK38_2061 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_207 ENOG4108R6K riboflavin synthase, subunit alpha AK38_2070 ENOG4105D3G Pseudouridine synthase AK38_2071 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) AK38_2079 ENOG4108RS6 transposase AK38_208 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AK38_2080 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) AK38_2082 ENOG4105DWK Membrane AK38_2083 ENOG4105N14 lysine exporter protein LysE YggA AK38_2084 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AK38_2087 ENOG4108RS6 transposase AK38_2089 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase AK38_209 ENOG4105CZQ inner membrane transport protein YdhC AK38_2092 ENOG4105DTN riboflavin biosynthesis protein ribF AK38_2094 ENOG41063Z6 transcriptional regulator, lysR family AK38_2098 ENOG4106HK8 GPR1 FUN34 yaaH family protein AK38_210 ENOG4105F52 Transcriptional regulator AK38_2100 ENOG4105CSH Transporter AK38_2101 ENOG4108RIR Molybdenum cofactor biosynthesis protein AK38_2109 ENOG41065U4 response regulator AK38_2110 ENOG4108RH0 Crea protein AK38_2113 ENOG4105UEI Transcriptional Regulator AraC Family AK38_2114 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) AK38_2116 ENOG4107SC1 transglycosylase AK38_2119 ENOG4108KHX Diguanylate cyclase AK38_2120 ENOG41090EK ompa motb domain protein AK38_2121 ENOG4105C5H ABC transporter AK38_2122 ENOG4105C5H ABC transporter AK38_2124 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase AK38_2125 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AK38_2126 ENOG4105EAC phosphoserine phosphatase AK38_2127 ENOG41062Z9 Membrane AK38_213 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AK38_2133 ENOG4105D9N nucleoside AK38_2134 ENOG4105EYA deoxyribonuclease AK38_2135 ENOG4108NRW Phospholipase, patatin family AK38_2137 ENOG4105K3G Periplasmic Protein AK38_2139 ENOG4105KEG ribosomal-protein-alanine acetyltransferase AK38_214 ENOG4105K4H Nlp p60 protein AK38_2140 ENOG4108WPU DNA polymerase III subunit psi AK38_2143 ENOG4105YBH Protein of unknown function (DUF1435) AK38_2144 ENOG4105BZU Histidine kinase AK38_2147 ENOG4105BZS acriflavin resistance protein AK38_2148 ENOG410624X efflux transporter, rnd family, mfp subunit AK38_2151 ENOG4105DKP glycosyl transferase, family 9 AK38_2152 ENOG4107RYS Autoinducer-2 (AI-2) kinase AK38_2153 ENOG4105DKT Transcriptional regulator AK38_2154 ENOG4105DKT Transcriptional regulator AK38_216 ENOG4105M2J Glutaredoxin AK38_2161 ENOG4105RI1 glycoprotein receptor AK38_2162 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AK38_2163 ENOG4105DM4 PTS System AK38_2164 ENOG4108YRF PTS System AK38_2165 ENOG4106R3P AraC family transcriptional regulator AK38_2166 ENOG4108XCZ PTS System AK38_2168 ENOG4108M3P Membrane AK38_217 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) AK38_218 ENOG4108UYE Lactoylglutathione lyase AK38_2180 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 AK38_2184 ENOG4105WSB biofilm stress and motility protein A AK38_2185 ENOG4105CSU acyl-Coa dehydrogenase AK38_2186 ENOG4105C2N RNA methyltransferase TrmH family group 3 AK38_2187 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AK38_2191 ENOG4105EPW hflc protein AK38_2192 ENOG4107QJR hflk protein AK38_2193 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AK38_2197 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AK38_2198 ENOG4105K8N protein family UPF0079, ATPase AK38_2199 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AK38_22 ENOG4105EDK PfkB domain protein AK38_220 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AK38_2200 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AK38_2203 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) AK38_2206 ENOG4105EGS Mechanosensitive ion channel AK38_221 ENOG4108WUH Transcriptional regulator, TetR family AK38_2211 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) AK38_2212 ENOG4108RS6 transposase AK38_2215 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AK38_2216 ENOG4108ZVF (LipO)protein AK38_222 ENOG4105DIJ Phosphoethanolamine transferase AK38_2221 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AK38_2224 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AK38_2225 ENOG4108RC0 Electron transport protein AK38_2226 ENOG4105BZ8 glutamate synthase AK38_2227 ENOG4108SIC Transcriptional regulator AK38_223 ENOG4105XZD Fe-S protein AK38_224 ENOG4107RGM aldo keto reductase AK38_2241 ENOG4105C0A alcohol dehydrogenase AK38_2243 ENOG4108UUM single-stranded DNA-binding protein AK38_2244 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AK38_2245 ENOG4105MSB protein, conserved in bacteria AK38_2246 ENOG4105CGF Aromatic amino acid aminotransferase AK38_2248 ENOG4105CDU Replicative dna helicase AK38_2249 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AK38_2250 ENOG4105P4Z Phage shock protein G AK38_2251 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AK38_2252 ENOG4105MYN Zinc uptake regulation protein AK38_2254 ENOG41080IJ Diacylglycerol kinase AK38_226 ENOG4108XTF Outer Membrane Lipoprotein AK38_2262 ENOG4108S1B Periplasmic chaperone protein AK38_2265 ENOG4108RS6 transposase AK38_2275 ENOG4105DAX Pfam:DUF2983 AK38_2279 ENOG4105D4P Coproporphyrinogen iii oxidase AK38_228 ENOG410642K Lysozyme inhibitor AK38_2280 ENOG41090JE Utilization Protein AK38_2282 ENOG4107ENK receptor AK38_2283 ENOG4106QJH hemin transport protein AK38_2284 ENOG4107R4I Periplasmic binding protein AK38_2285 ENOG4105EHG Permease protein AK38_2287 ENOG4105C28 cystathionine AK38_2288 ENOG4105C44 Serine transporter AK38_2289 ENOG4105EQ2 LysR family Transcriptional regulator AK38_2291 ENOG41066VF YeeE YedE family protein AK38_2292 ENOG4108IUF type iii secretion AK38_2293 ENOG4108TN6 type iii secretion AK38_2294 ENOG41083GP type iii secretion AK38_2295 ENOG4108HHI Type III secretion system protein AK38_2296 ENOG41063Q7 Type III secretion system protein AK38_2299 ENOG4108JIR Flagellum-specific ATP synthase AK38_23 ENOG4105CK5 oxidoreductase AK38_2311 ENOG4105BZU Histidine kinase AK38_2312 ENOG4105WH1 Two component transcriptional regulator luxr family AK38_2313 ENOG4105CK2 sodium dicarboxylate symporter AK38_2315 ENOG41062QD Membrane AK38_232 ENOG4108K3A Glutathione S-transferase AK38_2320 ENOG4108Z0R Transferase AK38_2323 ENOG4108WI1 Dna topoisomerase AK38_2325 ENOG4105C79 DNA protecting protein DprA AK38_2329 ENOG4105C1A potassium transporter peripheral membrane AK38_2331 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system AK38_2332 ENOG4105W1Y Transcriptional regulator AK38_2335 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) AK38_2339 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AK38_2341 ENOG4105VPB 50S ribosomal protein L30 AK38_235 ENOG4108ZR5 Conserved Protein AK38_2350 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal AK38_2352 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) AK38_2353 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) AK38_2355 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) AK38_2357 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) AK38_236 ENOG41069YE inner membrane protein yohC AK38_2363 ENOG4108RS6 transposase AK38_2366 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) AK38_237 ENOG4105DUX Transporter AK38_2371 ENOG4105WWK YheO domain protein AK38_2372 ENOG4108V1T peptidylprolyl cis-trans isomerase AK38_2374 ENOG4108YZY peptidylprolyl cis-trans isomerase AK38_2375 ENOG4105VKU nucleicacid-binding protein AK38_2378 ENOG4105C5H ABC transporter AK38_2379 ENOG4105C5H ABC transporter AK38_2380 ENOG4105K64 Glycosyl transferase, family 2 AK38_2382 ENOG4105E2B Taurine dioxygenase AK38_2383 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AK38_2385 ENOG4106FTQ Taurine ABC transporter, periplasmic AK38_2387 ENOG4105DNZ Alpha Beta Hydrolase AK38_2389 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) AK38_239 ENOG4105Q4T oxidoreductase AK38_2391 ENOG4108UKZ OsmC family AK38_2392 ENOG4107RYR Transcriptional regulator, Crp Fnr family AK38_2393 ENOG410613R integral membrane protein, YccS YhfK family AK38_2394 ENOG4105C8Y Acetylornithine aminotransferase AK38_2398 ENOG4105C8Y Acetylornithine aminotransferase AK38_24 ENOG4105CNN ABC, transporter AK38_240 ENOG4108JQ2 peptide transport system atp-binding protein AK38_2400 ENOG4105D7A ATP-binding protein AK38_2401 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AK38_2402 ENOG4105F8D glycoside hydrolase family 4 AK38_2403 ENOG41060NJ transcriptional regulator AK38_2406 ENOG4105DZC cytosine deaminase AK38_2407 ENOG4107QZF nitrite reductase NADPH large subunit AK38_2408 ENOG4105WZK nitrite reductase NADPH small subunit AK38_2409 ENOG4107V9H nitrite transporter AK38_241 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein AK38_2411 ENOG4105C31 Tryptophanyl-tRNA synthetase AK38_2412 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AK38_2413 ENOG4105DJV ribulose-phosphate 3-epimerase AK38_2418 ENOG4105E4G Type IV pilus AK38_242 ENOG4108EU3 peptide transport system, permease AK38_2423 ENOG4108JQC penicillin-binding protein 1A AK38_2424 ENOG4107RK2 ADP-ribose diphosphatase NudE AK38_2426 ENOG4105DQY intracellular growth attenuator AK38_2427 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 AK38_2428 ENOG4105VEJ Heat shock protein AK38_243 ENOG4108I5W peptide transport system, permease protein AK38_2431 ENOG4105E0F Histidine kinase AK38_2433 ENOG4108RRZ Transcription elongation factor GreB AK38_2434 ENOG4105BZM domain protein AK38_2435 ENOG4105XFK Ferrous iron transport protein A AK38_2436 ENOG4105CE1 Ferrous iron transport protein b AK38_2438 ENOG4105RID UPF0379 protein yhcN AK38_244 ENOG4108HIY periplasmic AK38_2440 ENOG4105MJ2 Competence protein AK38_2442 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) AK38_2443 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AK38_2444 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AK38_2446 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) AK38_2448 ENOG4105E98 transcriptional regulator DeoR family AK38_245 ENOG4108RS6 transposase AK38_2450 ENOG4105DQ6 Transposase AK38_2451 ENOG4105SYT Methylenetetrahydrofolate reductase AK38_2452 ENOG4105CFH Aspartokinase AK38_2453 ENOG4105C28 cystathionine AK38_2454 ENOG4105C28 cystathionine AK38_2456 ENOG4108Z12 YiaAB two helix domain-containing protein AK38_2458 ENOG4105C25 Primosomal protein n' AK38_246 ENOG4105E51 psp operon transcriptional activator AK38_2460 ENOG4105ETE Transcriptional regulator (LacI family AK38_2461 ENOG41063M6 Cell Division Protein AK38_2464 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AK38_2468 ENOG4108MBX Secretion Protein AK38_247 ENOG41087YS Phage shock protein A AK38_2472 ENOG4108JJA ABC, transporter AK38_2473 ENOG4108RS6 transposase AK38_2475 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AK38_2476 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AK38_2477 ENOG4105CBT Fructose-1,6-bisphosphatase AK38_2478 ENOG4105DP0 ferredoxin-NADP reductase AK38_2479 ENOG4108VTS Membrane AK38_248 ENOG4105YYT phage shock protein B AK38_2480 ENOG4105EBK exported protein AK38_2482 ENOG4107F9Y LysR family transcriptional regulator AK38_2484 ENOG4105JSC dimethylmenaquinone methyltransferase AK38_2485 ENOG4107QPK )-transporter AK38_2487 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AK38_249 ENOG4105FM1 phage shock protein C AK38_2492 ENOG4105FMW periplasmic AK38_2493 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_2494 ENOG4105E0F Histidine kinase AK38_2495 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AK38_2496 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AK38_2497 ENOG4105D7W serine acetyltransferase AK38_25 ENOG4105C2J ABC transporter AK38_2500 ENOG4105VW4 glutaredoxin 3 AK38_2501 ENOG4107YZP Rhodanese domain protein AK38_2503 ENOG41063SB peptidase AK38_2504 ENOG4105PXI polysaccharide deacetylase AK38_2505 ENOG4105PXI polysaccharide deacetylase AK38_2507 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AK38_2509 ENOG4105XA0 heptosyltransferase ii AK38_251 ENOG4105CM6 amino acid regulated cytosolic protein AK38_2510 ENOG4105D16 lipopolysaccharide heptosyltransferase i AK38_2511 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase AK38_2518 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AK38_2523 ENOG4105DSJ YicC domain protein AK38_2524 ENOG4105EN6 Membrane AK38_2528 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AK38_2529 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase AK38_2530 ENOG4105CB5 ATP-dependent DNA helicase recG AK38_2531 ENOG4105D6U Sodium Glutamate Symporter AK38_2532 ENOG4105C2W permease AK38_2533 ENOG4105JV1 AsmA family AK38_2534 ENOG4105SUU thioesterase domain AK38_2539 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 AK38_2540 ENOG4105CI3 gtp-binding protein typa AK38_2541 ENOG4105C5F glutamine synthetase AK38_2542 ENOG4105CUX Signal transduction histidine kinase AK38_2543 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AK38_2544 ENOG4105D4P Coproporphyrinogen iii oxidase AK38_2547 ENOG4108RS6 transposase AK38_2548 ENOG4105C2M dna polymerase I AK38_2549 ENOG4108Z33 Thiol disulfide Interchange Protein AK38_2550 ENOG4105E27 serine threonine protein kinase AK38_2551 ENOG4105PC1 Conserved Protein AK38_2553 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b AK38_2559 ENOG4107EJG GntR family transcriptional regulator AK38_256 ENOG4108RS6 transposase AK38_2561 ENOG4105C0R drug resistance transporter emrb qaca subfamily AK38_2562 ENOG4108RVA ribokinase AK38_2568 ENOG4108VVK transcriptional Regulator, AsnC AK38_2569 ENOG4105QTB Flavodoxin AK38_257 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AK38_2572 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation AK38_258 ENOG4107S8C mandelate racemase muconate lactonizing AK38_2583 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) AK38_2584 ENOG4105C8U phosphate abc transporter AK38_2585 ENOG4105E2Z phosphate ABC transporter (Permease AK38_2589 ENOG4106PMH Extracellular solute-binding protein family 3 AK38_259 ENOG4105KXI murein peptide amidase A AK38_2590 ENOG4105EAD ABC transporter AK38_2591 ENOG4105DRP amino acid AbC transporter AK38_2592 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 AK38_2593 ENOG4105C7N Xanthine uracil vitamin C permease AK38_2598 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AK38_26 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_260 ENOG4107QSI ABC, transporter AK38_2604 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AK38_2606 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_2607 ENOG410667J hydrolase AK38_2608 ENOG4105DQ6 Transposase AK38_2612 ENOG4105C7B Threonine dehydratase AK38_2613 ENOG4105D99 atp gtp-binding protein AK38_2614 ENOG4105D99 atp gtp-binding protein AK38_2615 ENOG4105R2A (LipO)protein AK38_2619 ENOG4105JKW Valine--pyruvate aminotransferase AK38_2621 ENOG4107T9C Alpha amylase catalytic region AK38_2624 ENOG4108ZG0 Ompa motb domain protein AK38_2626 ENOG4108R3E Dna-3-methyladenine glycosylase i AK38_2630 ENOG4106JH6 (LipO)protein AK38_2631 ENOG4105CTS PTS system mannitol-specific AK38_2633 ENOG4105E61 Mannitol repressor protein AK38_2635 ENOG4108YYI Protein of unknown function (DUF2810) AK38_2639 ENOG4105C8Q Methyl-accepting chemotaxis AK38_2640 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AK38_2642 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AK38_2643 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AK38_2644 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AK38_2645 ENOG4108MG3 formate dehydrogenase AK38_2650 ENOG4105D13 transposase AK38_2656 ENOG4105DQ6 Transposase AK38_2658 ENOG4105MEV Acyl-transferase AK38_2659 ENOG4106EAR Fimbrial protein AK38_266 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) AK38_2662 ENOG4108TTM chaperone AK38_2664 ENOG4105CMG Carbohydrate kinase AK38_2666 ENOG4105DFW ABC transporter AK38_2668 ENOG4108HWW ABC transporter AK38_2669 ENOG4105T16 Transcriptional regulator (AraC family) AK38_2671 ENOG4105DFP Integrase AK38_2673 ENOG4105ZTC transcriptional activator, Ogr delta AK38_2678 ENOG4108IPW abc transporter atp-binding protein AK38_268 ENOG4105KT7 mgtC SapB transporter AK38_2680 ENOG4105CM4 permease protein AK38_2686 ENOG4105C6T cysteine synthase AK38_2688 ENOG4105C84 Histidine ammonia-lyase AK38_2689 ENOG4105C85 amino acid AK38_269 ENOG4105IKK cytoplasmic protein AK38_2691 ENOG4105DIJ Phosphoethanolamine transferase AK38_2692 ENOG4108KX4 response regulator AK38_2693 ENOG4105BZU Histidine kinase AK38_2696 ENOG4105BZU Histidine kinase AK38_2697 ENOG4105CXY transporter AK38_27 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AK38_270 ENOG41090X5 Heat shock protein hslJ AK38_2701 ENOG4105D5K Hemolysin activator protein AK38_2703 ENOG4105DEF Extracellular solute-binding protein, family 5 AK38_2704 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_2705 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_2706 ENOG4105C3U ABC transporter AK38_2707 ENOG4108JQ7 (ABC) transporter AK38_2708 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) AK38_2709 ENOG4105BZU Histidine kinase AK38_271 ENOG4105C5I Dehydrogenase AK38_2710 ENOG4108PU9 oligogalacturonate-specific porin AK38_2715 ENOG4105CS0 peptidase AK38_2716 ENOG4107SS6 2-dehydro-3-deoxygluconokinase AK38_2717 ENOG4105VSH 4-oxalocrotonate tautomerase AK38_2718 ENOG4105CMB EAL domain-containing protein AK38_2719 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) AK38_272 ENOG4107H52 Dicarboxylate transport AK38_2720 ENOG41066T0 asmA family AK38_2721 ENOG4107H3J ribonuclease AK38_2726 ENOG4105BZW Glycerate kinase AK38_2727 ENOG4107QQ0 gntp family AK38_2728 ENOG4107VHA regulatoR AK38_2729 ENOG4105DC8 reductase AK38_273 ENOG410689M (LipO)protein AK38_2730 ENOG4105D6S protein involved in catabolism of external DNA AK38_2731 ENOG4105DGW oligopeptidase A AK38_2735 ENOG4108M6U Universal stress protein A AK38_2737 ENOG4108RS6 transposase AK38_2738 ENOG4105CJ3 phosphate transporter AK38_2739 ENOG4105CBX hi0933 family AK38_274 ENOG4105WXT Conserved Protein AK38_2742 ENOG4105CNN ABC, transporter AK38_2743 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_2745 ENOG4105D2N Aldolase AK38_2749 ENOG4105C2I pirin domain protein AK38_275 ENOG4105DEI Mannitol dehydrogenase AK38_2750 ENOG4105DIQ Transcriptional regulator AK38_2751 ENOG4105C6Z Gluconate AK38_2752 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AK38_2756 ENOG41076UM multiple antibiotic resistance (MarC)-related protein AK38_2757 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AK38_276 ENOG4105DKT Transcriptional regulator AK38_2763 ENOG4108HRK Histidine kinase AK38_2768 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AK38_2769 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AK38_2772 ENOG4105DQ6 Transposase AK38_2779 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AK38_278 ENOG4105CQ7 ATP-dependent helicase AK38_2783 ENOG4105X58 receptor AK38_2786 ENOG4107QZV Type I secretion membrane fusion protein AK38_2787 ENOG4105YHG TonB family AK38_2788 ENOG4107QN2 dihydrolipoyl dehydrogenase AK38_2789 ENOG4105EHV domain protein AK38_2791 ENOG4105C5Q Transcriptional regulator AK38_2794 ENOG4108Y73 Membrane AK38_2804 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator AK38_2805 ENOG4105C2J ABC transporter AK38_2806 ENOG4107R9N ABC transporter AK38_2808 ENOG41062B0 ABC transporter, permease AK38_2809 ENOG4108WFC UPF0438 protein yifE AK38_281 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap AK38_2810 ENOG4105C0P Mg chelatase subunit ChlI AK38_2812 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit AK38_2813 ENOG4105CM2 brancheD-chain amino acid aminotransferase AK38_2815 ENOG4105C7B Threonine dehydratase AK38_2822 ENOG4105EMY transcriptional regulator AK38_2828 ENOG4108VEV chaperone AK38_283 ENOG4105DS1 cytochrome b561 AK38_2830 ENOG4105CW0 outer membrane usher protein AK38_2831 ENOG4105GQR Chaperone AK38_2835 ENOG4105KQ5 peptidylprolyl cis-trans isomerase AK38_2836 ENOG4105C4R Atp-dependent dna helicase AK38_2841 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) AK38_2842 ENOG4105ESV Glycosyl transferase, family 4 AK38_2843 ENOG4105SFE lipopolysaccharide biosynthesis protein AK38_2844 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AK38_2845 ENOG4108IJ1 Dehydrogenase AK38_2846 ENOG4105C1B dTDP-glucose 4-6-dehydratase AK38_2847 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AK38_2848 ENOG4108WJ1 acetyltransferase AK38_2849 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AK38_2850 ENOG4105EGZ biosynthesis protein AK38_2854 ENOG4105C85 amino acid AK38_2860 ENOG4108RS6 transposase AK38_2861 ENOG410601J HemY protein AK38_2862 ENOG4105ECF c-methyltransferase AK38_2863 ENOG41076E6 Uroporphyrinogen-III Synthase AK38_2865 ENOG4107T0K Adenylate cyclase AK38_2867 ENOG4105S7Z (LipO)protein AK38_2869 ENOG4105CT0 Protein of unknown function, DUF484 AK38_287 ENOG4105CTD carboxy-peptidase AK38_2870 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AK38_2871 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant AK38_2872 ENOG4105C4R Atp-dependent dna helicase AK38_2874 ENOG4105EQN UPF0261 protein AK38_2877 ENOG4105FR1 rard protein AK38_2878 ENOG4108VUY thioesterase Superfamily protein AK38_2879 ENOG4105HDD phospholipase AK38_288 ENOG4105JJR Histidine kinase AK38_2880 ENOG4105C9U ATP-dependent DNA helicase RecQ AK38_2881 ENOG4105CCF Lysine exporter protein (Lyse ygga) AK38_2882 ENOG410829K Lysine exporter protein (Lyse ygga) AK38_2883 ENOG4108EUD Lysophospholipase AK38_2884 ENOG4105DQF Hydrolase AK38_2887 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase AK38_2888 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A AK38_289 ENOG4107EXC regulatoR AK38_2890 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AK38_2891 ENOG4108W1V Lipoprotein AK38_2892 ENOG4105EX9 Membrane AK38_2895 ENOG4107FS9 Membrane AK38_2898 ENOG4105MG3 Membrane AK38_2899 ENOG4106H78 methyltransferase AK38_29 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) AK38_2900 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AK38_2900 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AK38_2901 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AK38_2902 ENOG4105CAK Cell division ATP-binding protein ftsE AK38_2903 ENOG4105CRP Part of the ABC transporter FtsEX involved in AK38_2905 ENOG4108RS6 transposase AK38_2906 ENOG4105U59 -acetyltransferase AK38_2907 ENOG4105CP9 extracellular ligand-binding receptor AK38_2908 ENOG4105C32 Amino acid ABC transporter (Permease) AK38_2909 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AK38_291 ENOG4105D5Q Arginine ornithine antiporter AK38_2910 ENOG4105C0Z ABC transporter AK38_2911 ENOG4108IV0 ABC, transporter AK38_292 ENOG4105C5D exported protein AK38_2923 ENOG4107T6V glycerophosphoryl diester phosphodiesterase AK38_2924 ENOG4105RK9 auxin efflux carrier AK38_2925 ENOG4105DZ2 Transcriptional regulator AK38_2926 ENOG4105EMK carboxylate amino acid amine transporter AK38_2928 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) AK38_2929 ENOG4107SXA Phosphorylase AK38_293 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AK38_2932 ENOG4108KF1 Membrane AK38_2933 ENOG4105CGY Dna recombination protein AK38_2935 ENOG4105JC1 sterol-binding domain protein AK38_2937 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AK38_2939 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AK38_294 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AK38_2944 ENOG4105D52 delta-aminolevulinic acid dehydratase AK38_2945 ENOG4105MDZ Transcriptional activator rfaH AK38_2946 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AK38_2947 ENOG4107QK7 reductase AK38_295 ENOG4105Q9Y Universal stress protein AK38_2951 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AK38_2952 ENOG4108RS6 transposase AK38_2953 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AK38_2954 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) AK38_2955 ENOG4108RR8 protoporphyrinogen oxidase AK38_296 ENOG4105DS0 Transcriptional regulator, Crp Fnr family AK38_2961 ENOG4105D4A Cell wall formation (By similarity) AK38_2962 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase AK38_297 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AK38_2972 ENOG4105PM1 preprotein translocase subunit SecE AK38_2973 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AK38_2980 ENOG4108RS6 transposase AK38_2981 ENOG4105D41 biosynthesis protein thiH AK38_2982 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) AK38_2984 ENOG4105D06 uba thif-type nad fad binding protein AK38_2991 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) AK38_2992 ENOG4105R2J Conserved Protein AK38_2994 ENOG4108T8B Protein of unknown function (DUF1481) AK38_2995 ENOG4105C12 Phosphoribosylglycinamide synthetase AK38_3 ENOG4105CNI cell division protein FtsW AK38_30 ENOG4105C26 Dehydrogenase AK38_3008 ENOG4107QP3 malate synthase g AK38_3009 ENOG4108I9X Isocitrate lyase AK38_301 ENOG4105PAD Hydrolase AK38_3011 ENOG41069M3 Transcriptional regulator AK38_3012 ENOG41069M3 Transcriptional regulator AK38_3013 ENOG4105C3R Methionine synthase AK38_3016 ENOG4105CFH Aspartokinase AK38_3019 ENOG4105EG2 ABC transporter, permease AK38_302 ENOG4105M71 acetolactate synthase 1 regulatory subunit AK38_3020 ENOG4105D56 permease protein AK38_3021 ENOG4107FKK extracellular solute-binding protein family 1 AK38_3025 ENOG4107W52 maltose operon periplasmic protein AK38_3027 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_303 ENOG4105C7K acetolactate synthase AK38_3031 ENOG4105DQ6 Transposase AK38_3037 ENOG4105D4X repressor AK38_3038 ENOG4105C5Y PTS System AK38_3039 ENOG4105CG3 alpha amylase, catalytic region AK38_3040 ENOG4105NXH GreA GreB family elongation factor AK38_3041 ENOG4108XVM Cytochrome b(562) AK38_3043 ENOG4105CMS peptidase U62, modulator of DNA gyrase AK38_3045 ENOG4105UNR (Barnase) inhibitor AK38_3048 ENOG4105C26 Dehydrogenase AK38_3052 ENOG4105CR8 Transcriptional regulator AK38_3063 ENOG4105D1U peptidase U62 modulator of DNA gyrase AK38_3065 ENOG4105QD6 exported protein AK38_3066 ENOG4105C03 ribonuclease AK38_3067 ENOG4108Z03 MAF-like protein AK38_3068 ENOG4105VQ7 Rod shape-determining protein MreD AK38_3069 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AK38_3071 ENOG41062P1 Diguanylate cyclase phosphodiesterase AK38_3072 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family AK38_3073 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) AK38_3076 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AK38_3077 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AK38_3079 ENOG4105RG0 Membrane AK38_308 ENOG4105FYV Amp nucleosidase AK38_3080 ENOG4108IA2 Sodium pantothenate symporter AK38_3082 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AK38_3083 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) AK38_3086 ENOG4105CSH Transporter AK38_3087 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase AK38_3090 ENOG4108XTF Outer Membrane Lipoprotein AK38_3091 ENOG4105VEQ Cold shock protein AK38_3092 ENOG4105VEQ Cold shock protein AK38_3093 ENOG4108RS6 transposase AK38_3096 ENOG4105CYM Glutathione S-transferase AK38_3097 ENOG4105C2X Arabinose 5-phosphate isomerase AK38_3098 ENOG4105EF1 ribulokinase AK38_3100 ENOG4105CNN ABC, transporter AK38_3101 ENOG4105C2J ABC transporter AK38_3103 ENOG4105D1S lipid A biosynthesis AK38_3105 ENOG4105EEQ Na H antiporter AK38_3106 ENOG4105C7N Xanthine uracil vitamin C permease AK38_3109 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AK38_311 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_3111 ENOG4105GVF (ABC) transporter AK38_3114 ENOG4108RVA ribokinase AK38_3115 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) AK38_3116 ENOG4105W4W Transcriptional regulator AK38_3117 ENOG4107TYG Oxidoreductase domain-containing protein AK38_3120 ENOG4105CNA YD repeat protein AK38_3122 ENOG4105CS6 Rhs element vgr protein AK38_3128 ENOG4105CNA YD repeat protein AK38_313 ENOG41060NJ transcriptional regulator AK38_3131 ENOG4105CS6 Rhs element vgr protein AK38_3138 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_3148 ENOG4105KME endoribonuclease L-psp AK38_3151 ENOG41080Z8 PHOSPHOCARRIER protein AK38_3153 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN AK38_3154 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA AK38_3155 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_3156 ENOG4108IUZ ABC transporter AK38_3157 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA AK38_3158 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) AK38_3159 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase AK38_3160 ENOG4105C2X Arabinose 5-phosphate isomerase AK38_3161 ENOG4105FEU K -dependent Na -Ca exchanger AK38_3162 ENOG4105DHJ ABC, transporter AK38_3163 ENOG4105CY3 ABC transporter, permease AK38_3164 ENOG4107PE3 Mammalian cell entry related domain protein AK38_3165 ENOG4105E3I toluene tolerance AK38_3166 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane AK38_3167 ENOG4105VFK BolA family AK38_3169 ENOG4105C0H protease AK38_3170 ENOG4108RS6 transposase AK38_3171 ENOG4105C0H protease AK38_3172 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III AK38_3173 ENOG4105D6Z AFG1 family ATPase AK38_3176 ENOG4107MKT Stringent starvation protein a AK38_3177 ENOG4105KB2 stringent starvation protein b AK38_3179 ENOG4105BZ8 glutamate synthase AK38_318 ENOG4105MQ5 zona occludens toxin AK38_3180 ENOG4105CBC glutamate synthase AK38_3181 ENOG4105N5T Radical SAM Protein AK38_3182 ENOG4105BZU Histidine kinase AK38_3183 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain AK38_3185 ENOG4105W4M Transport-associated protein AK38_3189 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AK38_3190 ENOG4108CNN domain protein AK38_3191 ENOG4105CWB LysR family transcriptional Regulator AK38_3192 ENOG4105CHF Glutathione S-transferase AK38_3195 ENOG4108MXZ Esterase AK38_3197 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) AK38_3200 ENOG4108RS6 transposase AK38_3202 ENOG4105FHY Opacity-associated protein A AK38_3203 ENOG4108V1T peptidylprolyl cis-trans isomerase AK38_3205 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic AK38_3206 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase AK38_3207 ENOG4108UUE Transcriptional regulator AK38_3208 ENOG41061GZ Protein of unknown function (DUF1107) AK38_3209 ENOG4105C37 (CBS) domain AK38_3211 ENOG4105CFU surface antigen AK38_3214 ENOG4108ZHD aig2 family AK38_3215 ENOG4105F0N pyrophosphate phospho-hydrolase AK38_3216 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 AK38_3217 ENOG4105DFU Cell wall formation (By similarity) AK38_3221 ENOG4105HVQ Regulatory factor of maltose metabolism AK38_3223 ENOG4105EAH synthase AK38_3226 ENOG4105QYV Membrane AK38_3230 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase AK38_3232 ENOG4105HBR Rna-binding protein AK38_3234 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AK38_3235 ENOG4105EEI dihydropteroate synthase AK38_3237 ENOG4105NTZ Preprotein translocase subunit SecG AK38_3241 ENOG4105CHV Transcription elongation factor NusA AK38_3247 ENOG4105DQ6 Transposase AK38_3250 ENOG4105C1J atp-dependent rna helicase AK38_3253 ENOG4105DEN Luciferase family AK38_3256 ENOG4105BZS acriflavin resistance protein AK38_3257 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AK38_3261 ENOG4108YYD acetyltransferase AK38_3267 ENOG4105DRS transport system, permease AK38_3271 ENOG4105K4T epimerase AK38_3272 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein AK38_3273 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) AK38_3274 ENOG4105FD8 phosphonate metabolism protein PhnM AK38_3275 ENOG4105HRV phosphonate c-p lyase system protein phnl AK38_3276 ENOG4105ENV phosphonate C-P lyase system protein PhnK AK38_3277 ENOG4105FT8 Phosphonate metabolism AK38_3278 ENOG4105EKV Phosphonate metabolism protein AK38_3279 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH AK38_3280 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG AK38_3281 ENOG4107RJJ Transcriptional regulator AK38_3283 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) AK38_3284 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase AK38_3285 ENOG4108JQ7 (ABC) transporter AK38_3286 ENOG4105C3U ABC transporter AK38_3287 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_3288 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_3291 ENOG4105XEP YhcH YjgK YiaL family protein AK38_3293 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) AK38_3294 ENOG4108MJ3 acetyltransferase AK38_3295 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AK38_3296 ENOG4105MYG DNA polymerase iii, chi subunit AK38_3298 ENOG4108M8S permease YjgP YjgQ family protein AK38_3299 ENOG4108K5H permease YjgP YjgQ family protein AK38_330 ENOG4105CMQ Chloride channel AK38_3303 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AK38_3306 ENOG4108RS6 transposase AK38_331 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) AK38_3311 ENOG4105D7Q type ii secretion system AK38_3312 ENOG4107QHF type ii secretion system protein e AK38_3313 ENOG4108ZUW Major pilin subunit AK38_3314 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AK38_3315 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AK38_3316 ENOG4106A72 regulatory protein AmpE AK38_3317 ENOG4105C85 amino acid AK38_3318 ENOG41073TP transcriptional regulator AK38_3319 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AK38_3320 ENOG4107QSN dihydrolipoamide acetyltransferase AK38_3321 ENOG4107QN2 dihydrolipoyl dehydrogenase AK38_3322 ENOG4108RS6 transposase AK38_3323 ENOG4107QIJ Aconitate hydratase 2 AK38_3325 ENOG4105RPH Inner membrane protein YddG AK38_3328 ENOG4108ZRK uncharacterized protein yacC AK38_3329 ENOG4105E3B Multicopper oxidase AK38_333 ENOG4105DAG ROK family AK38_3330 ENOG4108UGV hypoxanthine phosphoribosyltransferase AK38_3331 ENOG41077A9 carbonic anhydrase AK38_3332 ENOG4105DA5 (ABC) transporter AK38_3333 ENOG4105E3A (ABC) transporter AK38_3334 ENOG4107BJW polysaccharide deacetylase AK38_3338 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AK38_3339 ENOG4105DJ0 Poly(A) Polymerase AK38_334 ENOG4106NZI LysR family Transcriptional regulator AK38_3340 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) AK38_3341 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters AK38_3343 ENOG4107XID 2'-5' rna ligase AK38_3344 ENOG4105CQ7 ATP-dependent helicase AK38_3345 ENOG4105BZ4 penicillin-binding protein AK38_3346 ENOG4105E0A ABC, transporter AK38_3347 ENOG4105J76 Periplasmic binding protein AK38_3348 ENOG4105S6R Iron-hydroxamate transporter permease subunit AK38_335 ENOG4105D94 Major Facilitator Superfamily AK38_3352 ENOG4105EN6 Membrane AK38_3356 ENOG4105C0H protease AK38_3357 ENOG4105BZU Histidine kinase AK38_3358 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AK38_3359 ENOG4105DXN mazG family AK38_336 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) AK38_3363 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AK38_3364 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase AK38_337 ENOG4105C9Q fumarate hydratase class II AK38_3375 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) AK38_3376 ENOG4105N0Z inner membrane protein ygbE AK38_338 ENOG4105EIP mannose-6-phosphate isomerase AK38_3383 ENOG4108K5P (LipO)protein AK38_3384 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_3386 ENOG4108YZG isomerase AK38_3387 ENOG4105CPQ Dehydrogenase AK38_3388 ENOG4105CHR reductase AK38_3389 ENOG4105CMT Dihydroxyacetone kinase AK38_339 ENOG4106J39 exported protein AK38_3391 ENOG4105DKT Transcriptional regulator AK38_3396 ENOG4105E89 ABC transporter AK38_3397 ENOG4105CA0 peroxidase AK38_3399 ENOG4105D05 Receptor AK38_34 ENOG4105DN3 alpha-2-macroglobulin domain protein AK38_3402 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AK38_3404 ENOG4107GFK fumarate AK38_3405 ENOG4105CMG Carbohydrate kinase AK38_3406 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase AK38_3407 ENOG4105F5R ABC transporter AK38_3408 ENOG4105CNN ABC, transporter AK38_3409 ENOG4105C2J ABC transporter AK38_341 ENOG4105DHU Bile acid AK38_3410 ENOG4108RS6 transposase AK38_3412 ENOG4105E98 transcriptional regulator DeoR family AK38_3413 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AK38_3414 ENOG4107QY8 reductase AK38_3415 ENOG4105QAX Iron-sulfur AK38_3416 ENOG4107KGK dmso reductase anchor subunit AK38_3417 ENOG4108NEM leader-binding protein dmsD AK38_3418 ENOG4105CPW cytochrome b561 AK38_3419 ENOG4108XVM Cytochrome b(562) AK38_342 ENOG4105D9R oxidoreductase AK38_3423 ENOG4105C2J ABC transporter AK38_3424 ENOG4105CNN ABC, transporter AK38_3425 ENOG4108HHA Transketolase AK38_3426 ENOG4108IUS Transketolase AK38_3427 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AK38_3439 ENOG4107VXZ Hydrolase AK38_344 ENOG4105CNN ABC, transporter AK38_3440 ENOG4105W39 Membrane AK38_3441 ENOG4105D9M gamma-glutamylcysteine synthetase AK38_3443 ENOG4108RS6 transposase AK38_3444 ENOG4108RS6 transposase AK38_3445 ENOG4108JU6 CBS domain protein AK38_3446 ENOG4106KVJ cytochrome C assembly protein AK38_3447 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY AK38_345 ENOG4105C2J ABC transporter AK38_3452 ENOG4108RS6 transposase AK38_3453 ENOG4108NE3 Salt-induced outer membrane protein AK38_3454 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AK38_3455 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AK38_3456 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AK38_3457 ENOG4108NEV two component transcriptional regulator, LytTR family AK38_3458 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AK38_3459 ENOG4105EHE chorismate mutase- prephenate dehydrogenase AK38_346 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator AK38_3464 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA AK38_3465 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AK38_3466 ENOG4105C34 Pseudouridine synthase AK38_3467 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AK38_3468 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_3475 ENOG4105T42 (LipO)protein AK38_3476 ENOG4105JIM Phosphatidylserine synthase AK38_3477 ENOG4105CD5 CoA-binding domain protein AK38_3478 ENOG4106IUH DTW domain containing protein AK38_3479 ENOG4105K63 Thioredoxin AK38_3480 ENOG4105EIB trna rrna methyltransferase AK38_3481 ENOG4105C0R drug resistance transporter emrb qaca subfamily AK38_3482 ENOG4105CW7 secretion protein, HlyD family AK38_3483 ENOG4105NTK Transcriptional repressor Mpra AK38_3484 ENOG4105ZED uncharacterized protein ygaH AK38_3485 ENOG4108UMN azlc family AK38_3486 ENOG4105EQ0 Major Facilitator superfamily AK38_3493 ENOG4105E5Q amino acid AbC transporter AK38_3495 ENOG4105C5R Aminotransferase AK38_3498 ENOG4105C5R Aminotransferase AK38_35 ENOG4108JQB penicillin-binding protein 1C AK38_350 ENOG4108JJA ABC, transporter AK38_3502 ENOG4106YJS accessory processing protein AK38_3504 ENOG4107QPN acyl-Coa dehydrogenase AK38_3506 ENOG4105F7V ErfK ybiS ycfS ynhG family protein AK38_3507 ENOG4105E7A Glutamine amidotransferase AK38_3509 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AK38_351 ENOG4105C42 Type I secretion membrane fusion protein (HlyD AK38_3510 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AK38_3514 ENOG4105CJ2 (LipO)protein AK38_3518 ENOG4105CIN aminoacyl-histidine dipeptidase AK38_3529 ENOG4105F2W methyltransferase AK38_353 ENOG4108JJA ABC, transporter AK38_3534 ENOG4105DKQ ROK family AK38_3538 ENOG4105EYH Exonuclease AK38_3539 ENOG4107RH8 nuclease SbcCD subunit D AK38_354 ENOG4105M9B inner membrane protein ydgK AK38_3540 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AK38_3541 ENOG4105BZU Histidine kinase AK38_3542 ENOG4105DJH phosphate AK38_3543 ENOG4105CWM branched-chain amino acid transport system II carrier protein AK38_3544 ENOG4105C85 amino acid AK38_3545 ENOG4107R28 alpha amylase, catalytic region AK38_3546 ENOG4105CHR reductase AK38_3549 ENOG4108RS6 transposase AK38_3550 ENOG4105D3R alkyl hydroperoxide reductase AK38_3554 ENOG4105VIE preprotein translocase, subunit YajC AK38_3555 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AK38_3556 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AK38_3557 ENOG4108RS6 transposase AK38_3561 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AK38_3564 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AK38_3565 ENOG4108ZAI phosphatidylglycerophosphatase a AK38_3566 ENOG4108RS6 transposase AK38_3568 ENOG4105CTB Polyprenyl synthetase AK38_3571 ENOG4107S0N DJ-1 family AK38_3572 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) AK38_3574 ENOG4107RDB Major Facilitator AK38_3576 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) AK38_3577 ENOG4105CCU oxidase (Subunit III) AK38_3578 ENOG4105BZ9 Cytochrome C oxidase, subunit I AK38_3579 ENOG4105E2S oxidase) subunit II AK38_358 ENOG4105UEI Transcriptional Regulator AraC Family AK38_3580 ENOG4108NFH Sugar hydrolase AK38_3581 ENOG4105EYM Major Facilitator superfamily AK38_3582 ENOG4105IEY (LipO)protein AK38_3583 ENOG4105M85 Bola protein AK38_3588 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AK38_3589 ENOG4105K70 DNA-binding protein AK38_359 ENOG4105D6A Electron transport complex AK38_3590 ENOG4105EIN peptidylprolyl cis-trans isomerase AK38_3591 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein AK38_3592 ENOG4108TGP Thioesterase superfamily protein AK38_3594 ENOG4108NFA extracellular solute-binding protein AK38_3596 ENOG4105C6T cysteine synthase AK38_3597 ENOG4108XM1 transcriptional regulator AsnC family AK38_3598 ENOG4105BZ1 (ABC) transporter AK38_3599 ENOG4105BZ1 (ABC) transporter AK38_360 ENOG4108UQQ Electron transport complex AK38_3600 ENOG4108YZA Nitrogen regulatory protein pii AK38_3601 ENOG4105BZU Histidine kinase AK38_3602 ENOG4105C29 acyl-CoA thioesterase AK38_3603 ENOG4108MNP Glycoprotein polysaccharide metabolism AK38_3604 ENOG41080UX Methyltransferase AK38_3605 ENOG4105KF5 hemolysin expression-modulating protein AK38_3606 ENOG4108UKR Biofilm formation regulator YbaJ AK38_3608 ENOG4105YK5 50S ribosomal protein L36 AK38_3610 ENOG4105BZS acriflavin resistance protein AK38_3611 ENOG4105C1P efflux transporter, rnd family, mfp subunit AK38_3612 ENOG4107XI7 Tetr family transcriptional regulator AK38_3613 ENOG41090EX DsrE family AK38_3614 ENOG4105EGS Mechanosensitive ion channel AK38_3616 ENOG4105WD1 Membrane AK38_362 ENOG4105CSM endonuclease III AK38_3620 ENOG4107QMP dna polymerase iii subunits gamma and tau AK38_3626 ENOG4108EX3 reductase AK38_3627 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase AK38_3628 ENOG4105FAW cDP-glucose 4,6-dehydratase AK38_3629 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AK38_363 ENOG4105EXW epimerase dehydratase AK38_3630 ENOG4108SMP Nad-dependent epimerase dehydratase AK38_3638 ENOG4108TJN glycosyl transferase group 1 AK38_3639 ENOG4105C0K Gdp-mannose 4,6-dehydratase AK38_364 ENOG4105CSP Major Facilitator Superfamily AK38_3640 ENOG4105C0K Gdp-mannose 4,6-dehydratase AK38_3643 ENOG4105CJT Mannose-1-phosphate guanylyltransferase AK38_3646 ENOG4108QY5 Ferric enterobactin transport protein AK38_3647 ENOG4107RE1 Inosine-guanosine kinase AK38_3648 ENOG4105CKD glutathione-regulated potassium-efflux system protein AK38_3649 ENOG4105EU0 Major facilitator Superfamily AK38_3650 ENOG4105CGH 5'-nucleotidase AK38_3651 ENOG4105CGH 5'-nucleotidase AK38_3652 ENOG4105CGH 5'-nucleotidase AK38_3655 ENOG4108Z66 YbaK ebsC protein AK38_3656 ENOG4105MBR gumn family AK38_3657 ENOG4105C59 p-type ATPase AK38_3658 ENOG4108Z6Z Transcriptional regulator AK38_3659 ENOG4105G5H Membrane AK38_366 ENOG4105D22 carbon starvation protein AK38_3660 ENOG4107QX8 SPFH domain, Band 7 family protein AK38_3661 ENOG4107QR8 Thioredoxin AK38_3662 ENOG4105E1F short-chain dehydrogenase reductase AK38_3663 ENOG4108UJV acyl-CoA thioesterase i AK38_3664 ENOG4108I0Y (ABC) transporter AK38_3665 ENOG4105CV6 ABC transporter, permease AK38_3666 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AK38_3667 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AK38_3669 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AK38_367 ENOG4105VCD cytoplasmic protein AK38_3672 ENOG4108RS6 transposase AK38_3674 ENOG4105K89 arsenate reductase AK38_3675 ENOG4105ERG peptidase m48, ste24p AK38_3676 ENOG4105C02 permease AK38_3679 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AK38_368 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AK38_3680 ENOG4105RH4 Glycine cleavage system transcriptional repressor AK38_3682 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AK38_3683 ENOG4108RS6 transposase AK38_3685 ENOG4105CGZ zinc metallopeptidase AK38_3691 ENOG4105KUZ arsenate reductase AK38_3693 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC AK38_3694 ENOG4107Z33 ABC transporter, permease AK38_3695 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AK38_3696 ENOG4105ENH Sulfatase AK38_3697 ENOG4105C4X radical SAM domain protein AK38_3698 ENOG4105S2T inner membrane protein YbcI AK38_370 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AK38_3700 ENOG4105BZS acriflavin resistance protein AK38_3702 ENOG4105WH1 Two component transcriptional regulator luxr family AK38_3703 ENOG4108ZNS ferredoxin-type protein NapF AK38_3704 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase AK38_3706 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) AK38_3707 ENOG4105CUW cytochrome C-TYPE protein AK38_3709 ENOG4105C6K Malic enzyme AK38_3716 ENOG4105H4F exported protein AK38_3717 ENOG4105E7K (LipO)protein AK38_3718 ENOG4105EZR dyp-type peroxidase family protein AK38_372 ENOG4108ZJT translation initiation factor, Sui1 AK38_3723 ENOG4108R66 Conserved Protein AK38_3724 ENOG4105QEK Transcriptional regulator AK38_3726 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein AK38_3727 ENOG4108I5D sulfate abc transporter AK38_3728 ENOG4105ECW sulfate abc transporter AK38_3729 ENOG4108IJ6 ABC transporter AK38_3730 ENOG4105C6T cysteine synthase AK38_3732 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AK38_3733 ENOG41062D9 Histidine kinase AK38_3735 ENOG4105C87 Aminotransferase class I and II AK38_3737 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AK38_3739 ENOG4105E1V na solute symporter AK38_3742 ENOG4105DJY efflux transporter, rnd family, mfp subunit AK38_3743 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_3744 ENOG4105E0F Histidine kinase AK38_3746 ENOG4108RS6 transposase AK38_3747 ENOG4105C5Y PTS System AK38_3748 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AK38_375 ENOG4105CFV Tetratricopeptide repeat protein AK38_3750 ENOG4105C6T cysteine synthase AK38_3751 ENOG4105EXN Sulfate transport protein CysZ AK38_3754 ENOG4105VRT cytoplasmic protein AK38_376 ENOG4105Q4A inner membrane protein yciS AK38_3760 ENOG4108RS6 transposase AK38_3766 ENOG4105D9N nucleoside AK38_3769 ENOG4105CPC Aldo Keto reductase AK38_377 ENOG4105EYK Phosphatidylglycerophosphatase B AK38_3770 ENOG4105C5Q Transcriptional regulator AK38_3773 ENOG41072TH Protein of unknown function (DUF1479) AK38_3774 ENOG4105CHM Aminotransferase AK38_3775 ENOG4108VKM cytochrome b561 AK38_3777 ENOG4106B0W Curli production assembly transport component CsgG AK38_3779 ENOG4107Y60 (LipO)protein AK38_3781 ENOG4108NEM leader-binding protein dmsD AK38_3782 ENOG4107KGK dmso reductase anchor subunit AK38_3783 ENOG4105QAX Iron-sulfur AK38_3784 ENOG4107QY8 reductase AK38_3786 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_379 ENOG4107QM5 aconitate hydratase AK38_3791 ENOG4105CVE Lytic murein transglycosylase AK38_3801 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_3803 ENOG4105GQR Chaperone AK38_3804 ENOG4105CW0 outer membrane usher protein AK38_3806 ENOG4105CW0 outer membrane usher protein AK38_381 ENOG4107R11 Transcriptional regulator AK38_3816 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) AK38_3818 ENOG4108RS6 transposase AK38_3819 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AK38_382 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AK38_3820 ENOG4106G6Q Transcriptional regulator AK38_3822 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB AK38_3823 ENOG4108Z6B deaminase AK38_3829 ENOG4108RS6 transposase AK38_3830 ENOG4107WP9 Histidine kinase AK38_3831 ENOG4108SKK alpha helix protein AK38_3832 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AK38_3833 ENOG4105C4K Nad synthetase AK38_3834 ENOG4108YZA Nitrogen regulatory protein pii AK38_3837 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AK38_384 ENOG4105RKX Protein of unknown function (DUF2498) AK38_3840 ENOG4108MN2 Stationary phase inducible protein CsiE AK38_3841 ENOG4105D8G Major Facilitator superfamily AK38_3842 ENOG41065CD Exported protein AK38_3843 ENOG4105D7X high-affinity nickel-transporter AK38_3844 ENOG4108RS6 transposase AK38_3845 ENOG4105ECY inositol monophosphatase AK38_3848 ENOG4105C3J Cysteine desulfurase AK38_3849 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins AK38_385 ENOG4105ERU peptidase AK38_3852 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB AK38_3853 ENOG4108ZIT Ferredoxin, 2FE-2S AK38_3854 ENOG4105WVQ Fe-S assembly protein IscX AK38_3856 ENOG4105YYA enhanced serine sensitivity protein SseB AK38_3858 ENOG4108MGN ATP-binding component of a transport system AK38_3859 ENOG4108MGN ATP-binding component of a transport system AK38_386 ENOG4105UBK short-chain dehydrogenase reductase AK38_3867 ENOG4105N21 Membrane AK38_3868 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AK38_387 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase AK38_3871 ENOG4105VPD cellular component movement AK38_3873 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AK38_3875 ENOG4108RS6 transposase AK38_3876 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_388 ENOG4105FE9 pseudouridine synthase AK38_3885 ENOG4105DWF phosphomethylpyrimidine kinase AK38_3888 ENOG4108ZGU inhibitor of vertebrate lysozyme AK38_389 ENOG4107RTD sua5 ycio yrdc ywlc family protein AK38_3890 ENOG4105CFP Peptidase U32 AK38_3891 ENOG4105KWI UPF0339 protein AK38_3892 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_3893 ENOG4105EB3 Histidine kinase AK38_3898 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AK38_390 ENOG4105DB7 PHP domain protein AK38_3900 ENOG4108JPW Aminotransferase AK38_3902 ENOG4105F38 ABC transporter, permease AK38_3903 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component AK38_3904 ENOG4105R8A Heat shock protein AK38_3905 ENOG4105CJW magnesium transporter AK38_3906 ENOG4105C9X ppx gppa phosphatase AK38_3907 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) AK38_3908 ENOG4105C8U phosphate abc transporter AK38_3909 ENOG4105E2Z phosphate ABC transporter (Permease AK38_3911 ENOG4108C80 FliB family AK38_3912 ENOG4108C80 FliB family AK38_3913 ENOG4108MK9 spermidine N(1)-acetyltransferase AK38_3914 ENOG4108V3E phosphoribosylglycinamide formyltransferase AK38_3917 ENOG4108RS6 transposase AK38_3918 ENOG4105WQ3 Rna-binding protein AK38_392 ENOG4105DDQ anthranilate synthase AK38_3926 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase AK38_3927 ENOG4108HPI phosphatidate Cytidylyltransferase AK38_3929 ENOG4105E8V Alpha Beta Hydrolase Fold protein AK38_3930 ENOG41077RS Phosphatase AK38_3935 ENOG4105EQ2 LysR family Transcriptional regulator AK38_3936 ENOG4107SET aldo keto reductase AK38_394 ENOG4105DK0 Indole-3-glycerol phosphate synthase AK38_3943 ENOG4105EZE Cupin 4 family protein AK38_3948 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_3952 ENOG4105HVQ Regulatory factor of maltose metabolism AK38_3953 ENOG4108JQB penicillin-binding protein 1C AK38_3954 ENOG4105D5G Transposase AK38_3956 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC AK38_3957 ENOG4105PTV Nudix Hydrolase AK38_3958 ENOG4108RE9 Phosphodiesterase AK38_3960 ENOG4105ECP epimerase AK38_3961 ENOG4108JEH abc transporter atp-binding protein AK38_3962 ENOG4106YG3 ABC transporter AK38_3963 ENOG4105DSP amino acid AbC transporter AK38_3964 ENOG4105E89 ABC transporter AK38_3965 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AK38_3966 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase AK38_3967 ENOG4105E96 Colicin v production protein AK38_3968 ENOG4108S3P Sporulation domain protein AK38_3969 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AK38_3971 ENOG4105DQR SNARE associated Golgi AK38_3973 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AK38_3974 ENOG4108RS6 transposase AK38_3977 ENOG410631K Membrane AK38_3978 ENOG4106WZ1 flagella biosynthesis regulator AK38_398 ENOG4105EIF outer membrane protein W AK38_3981 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_3983 ENOG4105MH2 YfcL protein AK38_3984 ENOG4108BPE -transporting atpase AK38_3985 ENOG4105EJ9 Membrane AK38_3986 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) AK38_3988 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) AK38_3990 ENOG4108BY2 phosphohistidine phosphatase AK38_3993 ENOG4105KZW UPF0381 protein AK38_3994 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation AK38_3995 ENOG410903C (LipO)protein AK38_3996 ENOG4105KWW Biogenesis protein AK38_3997 ENOG4105KWW Biogenesis protein AK38_3998 ENOG4107QX9 Thiol disulfide interChange protein AK38_3999 ENOG4105DA4 cytochrome c-type biogenesis protein AK38_4 ENOG4105K6T rare lipoprotein A AK38_40 ENOG4107P2S Transcriptional regulator AK38_4001 ENOG4105X3C heme exporter protein AK38_4002 ENOG41060IM Heme exporter protein AK38_4003 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) AK38_4007 ENOG4108V0P LemA family AK38_4009 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AK38_4015 ENOG4105CS6 Rhs element vgr protein AK38_4023 ENOG4105C3F Signal peptidase i AK38_4026 ENOG4105WMJ Positive regulator of sigma E, RseC MucC AK38_4027 ENOG4105VQK sigma E regulatory protein, MucB RseB AK38_403 ENOG4105NAU thioesterase Superfamily protein AK38_4030 ENOG4108IYU L-aspartate oxidase AK38_4032 ENOG4105C1J atp-dependent rna helicase AK38_404 ENOG4105D5G Transposase AK38_4043 ENOG4107R7A Allophanate hydrolase subunit 2 AK38_4044 ENOG4105P4J Allophanate hydrolase, subunit 1 AK38_4046 ENOG4107QNR UPF0135 protein AK38_4047 ENOG4107RF4 Phosphodiesterase AK38_4048 ENOG4105CVP deoxyribo-dipyrimidine photolyase AK38_4049 ENOG4107SEY Conserved Protein AK38_4050 ENOG4105XIQ Protein of unknown function (DUF2517) AK38_4054 ENOG4105C08 Histidine kinase AK38_4055 ENOG4105EEX Two component transcriptional regulator (Winged helix family AK38_4059 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 AK38_406 ENOG410822N TonB family AK38_4064 ENOG4105EZV Transcriptional regulator AK38_4065 ENOG4105VCP PTS System AK38_4066 ENOG4105CK1 PTS System AK38_4067 ENOG4105VZJ PTS System AK38_4068 ENOG41085Q9 Protein CrcB homolog AK38_407 ENOG4105K9H YciI-like protein AK38_4070 ENOG4107SVH Potassium channel protein AK38_4071 ENOG4105XXV Acid-resistance protein AK38_4075 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) AK38_4080 ENOG4108YZ9 Urea amidohydrolase subunit gamma AK38_4082 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) AK38_4083 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) AK38_4084 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_4085 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_4086 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein AK38_4087 ENOG4105VEQ Cold shock protein AK38_4091 ENOG4108SAJ Protein of unknown function (DUF1198) AK38_4092 ENOG4108WMJ Protein of unknown function (DUF2002) AK38_4097 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AK38_4098 ENOG4108IJ7 Glycine betaine AK38_4099 ENOG4108HQS Glycine betaine AK38_41 ENOG4105C6K Malic enzyme AK38_410 ENOG4108T1M outer membrane protein x AK38_4100 ENOG4105GIJ Glycine betaine AK38_4107 ENOG4105DFP Integrase AK38_4110 ENOG4105EV9 Alpha Beta Hydrolase AK38_4112 ENOG4105NNH LexA regulated protein AK38_4113 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) AK38_4114 ENOG41090R7 Ferric uptake AK38_4119 ENOG4108RS6 transposase AK38_4120 ENOG4105CI1 PTS System AK38_4122 ENOG4105CE4 GlcNAc 6-P deacetylase AK38_4123 ENOG4105E2R ROK family AK38_4124 ENOG4105D4U had-superfamily hydrolase, subfamily iia AK38_4125 ENOG4105CAQ asparagine synthetase AK38_4131 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AK38_4132 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AK38_4133 ENOG4105C9A Phoh family AK38_4135 ENOG4108JU5 Magnesium and cobalt efflux protein AK38_4136 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) AK38_4137 ENOG4107RP9 extracellular solute-binding protein, family 3 AK38_4138 ENOG4105EAD ABC transporter AK38_4139 ENOG4105DRP amino acid AbC transporter AK38_414 ENOG4108JQ7 (ABC) transporter AK38_4140 ENOG4105CDA abc transporter atp-binding protein AK38_4141 ENOG4107PAI alpha helical protein AK38_4144 ENOG4105DJF DNA polymerase III, delta' subunit AK38_4146 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) AK38_415 ENOG4105C3U ABC transporter AK38_4153 ENOG4108D1K outer membrane usher protein AK38_4154 ENOG4108UIF Chaperone AK38_4155 ENOG4106PHM regulatory protein AK38_4157 ENOG4105EQR Transposase IS116 IS110 IS902 AK38_416 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_4166 ENOG4106RMF ParB family AK38_417 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_4171 ENOG41073YN Protein of unknown function (DUF1380) AK38_4175 ENOG4105FEQ ParB domain protein nuclease AK38_4178 ENOG4106J5W DNA polymerase III (alpha subunit) AK38_418 ENOG4107QSI ABC, transporter AK38_4184 ENOG4105C2M dna polymerase I AK38_4186 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) AK38_419 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein AK38_4195 ENOG4106JVB Replication Protein AK38_4197 ENOG4105D2X ABC transporter substrate-binding protein AK38_420 ENOG4105C0A alcohol dehydrogenase AK38_4203 ENOG4108RS6 transposase AK38_4212 ENOG4105CB5 ATP-dependent DNA helicase recG AK38_4213 ENOG4105FA0 parb-like partition protein AK38_4214 ENOG4105FA0 parb-like partition protein AK38_4232 ENOG4108NYK Tape measure protein AK38_4239 ENOG4108X9F tail fiber protein AK38_4239 ENOG4108X9F tail fiber protein AK38_4241 ENOG4105UZW Tail fiber assembly protein AK38_4244 ENOG4106J5W DNA polymerase III (alpha subunit) AK38_4253 ENOG4105CMM transposase AK38_426 ENOG4105C6Y Udp-glucose 6-dehydrogenase AK38_4260 ENOG4105CMM transposase AK38_4264 ENOG4108C33 Resolvase AK38_4266 ENOG4105D13 transposase AK38_427 ENOG4105I93 response regulator AK38_4276 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) AK38_4277 ENOG4106CQM replication AK38_4286 ENOG4105CMM transposase AK38_4288 ENOG4105CMM transposase AK38_430 ENOG4105CIY formyltetrahydrofolate deformylase AK38_433 ENOG4105SKE transcriptional Regulator LysR family AK38_434 ENOG4105CGK Exodeoxyribonuclease III AK38_435 ENOG4105M6F mutator MutT protein AK38_436 ENOG4105MTM Protein of unknown function (DUF1496) AK38_437 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AK38_438 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) AK38_439 ENOG41069NU Nitroreductase AK38_440 ENOG4105D07 Signal peptide peptidase, SppA AK38_441 ENOG4105HDK L-asparaginase AK38_442 ENOG4108RWI nicotinamidase AK38_443 ENOG4105VUT cytoplasmic protein AK38_446 ENOG4105DSB aldose 1-epimerase AK38_447 ENOG4105GNX MltA-interacting MipA family protein AK38_448 ENOG4105CYN Serine protein kinase AK38_45 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 AK38_451 ENOG4105HEI LysR family (Transcriptional regulator AK38_452 ENOG4105EUB pirin domain protein AK38_453 ENOG4105CNH Multidrug resistance protein MdtL AK38_455 ENOG4105ED1 spovr family AK38_46 ENOG4107QWE )-transporter AK38_461 ENOG4105C3J Cysteine desulfurase AK38_464 ENOG4105UZW Tail fiber assembly protein AK38_479 ENOG4108RS6 transposase AK38_48 ENOG4105CHM Aminotransferase AK38_49 ENOG4107NQ8 LysR family Transcriptional regulator AK38_5 ENOG4105DZ1 carboxypeptidase AK38_509 ENOG4105HRS Antitermination protein AK38_51 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AK38_511 ENOG4105NY2 NinB protein AK38_520 ENOG4107R08 Integrase AK38_522 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AK38_523 ENOG4105CVE Lytic murein transglycosylase AK38_526 ENOG4107QMS site-determining protein AK38_527 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) AK38_528 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) AK38_529 ENOG4105CEY Amp-dependent synthetase and ligase AK38_53 ENOG4105GKE subunit e AK38_530 ENOG4105Y4Z Outer Membrane Lipoprotein AK38_531 ENOG41072GX Peptidase M22 Glycoprotease AK38_532 ENOG4105DVT helicase AK38_533 ENOG4105M4H endoribonuclease L-psp AK38_536 ENOG4108UHU Aldolase AK38_538 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AK38_539 ENOG4106KNT transcriptional regulator AK38_54 ENOG4107QIZ NADH dehydrogenase AK38_540 ENOG4105CA9 Pyruvate kinase AK38_541 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase AK38_542 ENOG4105DR5 peptidase AK38_543 ENOG4105NXV High-affinity zinc uptake system protein AK38_545 ENOG4105FAV ABC, transporter AK38_55 ENOG4108IEH NADH dehydrogenase subunit g AK38_550 ENOG4108TIT dATP pyrophosphohydrolase AK38_552 ENOG41081XQ Conserved Protein AK38_553 ENOG4105WJG Glutathione AK38_557 ENOG4106ZCM YecM protein AK38_561 ENOG4105CJR Integral membrane protein (MviN AK38_562 ENOG4105EP9 oxidoreductase AK38_563 ENOG4105D9U N-acetyltransferase AK38_565 ENOG4105F3T (LipO)protein AK38_566 ENOG4107XHZ cytoplasmic chaperone TorD family protein AK38_569 ENOG4105E2R ROK family AK38_570 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AK38_571 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AK38_572 ENOG4108RS6 transposase AK38_574 ENOG4105F38 ABC transporter, permease AK38_575 ENOG4105EG2 ABC transporter, permease AK38_579 ENOG4105CHH sulfate transporter AK38_58 ENOG4107UFS subunit j AK38_582 ENOG4105CHH sulfate transporter AK38_583 ENOG4108RS6 transposase AK38_585 ENOG41063JG Transcriptional regulator AK38_586 ENOG4108YY7 Invasion gene expression up-regulator SirB AK38_587 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AK38_592 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AK38_593 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria AK38_595 ENOG4105C3G gtp-binding protein AK38_60 ENOG4105D65 subunit l AK38_604 ENOG4105ENX hydrolase AK38_606 ENOG4105GR3 Histidine kinase AK38_61 ENOG4105C8S subunit m AK38_615 ENOG4108WF3 methyltransferase AK38_629 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AK38_630 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AK38_631 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AK38_633 ENOG41090B9 response to stress AK38_634 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) AK38_635 ENOG4105CZE histidine utilization repressor AK38_64 ENOG4108R66 Conserved Protein AK38_645 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component AK38_648 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AK38_65 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AK38_66 ENOG4105CHR reductase AK38_668 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_67 ENOG4105F32 YngK protein AK38_679 ENOG4105WH1 Two component transcriptional regulator luxr family AK38_68 ENOG4105K2J Transcriptional regulator AK38_680 ENOG4105XVG cytoplasmic protein AK38_681 ENOG4105RA2 Membrane AK38_683 ENOG4108T1M outer membrane protein x AK38_685 ENOG4105C85 amino acid AK38_689 ENOG410650H (LipO)protein AK38_69 ENOG4105C5I Dehydrogenase AK38_690 ENOG4105EKT )-iron permease AK38_691 ENOG4105CK7 Sodium proline symporter AK38_693 ENOG4105C26 Dehydrogenase AK38_696 ENOG4105CDA abc transporter atp-binding protein AK38_697 ENOG4105E5Q amino acid AbC transporter AK38_698 ENOG4105EAB amino acid AbC transporter AK38_700 ENOG4108M9K flagella biosynthesis protein FliZ AK38_701 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_702 ENOG4105I03 Flagellin AK38_703 ENOG4105DTS flagellar hook-associated AK38_704 ENOG4105MQ3 flagellar protein FliS AK38_706 ENOG4108NKV transcriptional regulator AK38_707 ENOG4108T5G Adenylate AK38_708 ENOG4105DHT Metal Dependent Phosphohydrolase AK38_712 ENOG4105VQ0 flagellar hook-basal body complex protein fliE AK38_713 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AK38_714 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AK38_715 ENOG41090PJ Flagellar assembly protein AK38_716 ENOG4108JIR Flagellum-specific ATP synthase AK38_717 ENOG4105GSA Flagellar export protein flij AK38_718 ENOG4105WF4 Flagellar hook-length control protein AK38_719 ENOG4107ZI8 flagellar basal body-associated protein flil AK38_72 ENOG4105C01 Dihydroxy-acid dehydratase AK38_720 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AK38_721 ENOG4105DD5 Flagellar motor switch protein AK38_723 ENOG4105CN7 Flagellar biosynthetic protein FliP AK38_725 ENOG4105D19 Role in flagellar biosynthesis (By similarity) AK38_728 ENOG4108MGF sugar kinase AK38_729 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AK38_730 ENOG4105C2J ABC transporter AK38_732 ENOG4105CNN ABC, transporter AK38_734 ENOG4105DKT Transcriptional regulator AK38_735 ENOG4105DTJ flagellar hook-associated protein AK38_736 ENOG4105E1Q flagellar hook-associated protein AK38_737 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj AK38_74 ENOG4105TNS Conserved Protein AK38_740 ENOG4105CGA flagellar basal-body rod protein FlgG AK38_741 ENOG4108KPB Flagellar basal-body rod protein FlgF AK38_742 ENOG4105BZE flagellar hook protein, FlgE AK38_743 ENOG4105W00 Flagellar hook capping protein AK38_744 ENOG4108ZC9 flagellar basal-body rod protein flgc AK38_745 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AK38_746 ENOG4105CKS Flagella basal body P-ring formation protein flgA AK38_747 ENOG4105M9M anti-sigma28 factor FlgM AK38_748 ENOG4105QVD Flagella synthesis protein FlgN AK38_750 ENOG4108RS6 transposase AK38_752 ENOG4105W13 flagellar protein AK38_753 ENOG4105D7B Flagellar biosynthesis protein flha AK38_754 ENOG4105D00 flagellar biosynthetic protein flhB AK38_757 ENOG4105NKT exported protein AK38_759 ENOG4105FXM Copper resistance protein AK38_76 ENOG4105E4F Isochorismate synthase AK38_760 ENOG41090A1 ferritin AK38_761 ENOG4105MPK DNA polymerase III subunit theta AK38_763 ENOG4105CUG Oligopeptidase b AK38_766 ENOG4105X2V dna damage-inducible protein AK38_767 ENOG4105C1J atp-dependent rna helicase AK38_770 ENOG4105CRQ synthase (Component I) AK38_772 ENOG4105EJQ L-serine dehydratase AK38_773 ENOG4107UWN reductase AK38_774 ENOG4105EFA 4-hydroxyphenylacetate AK38_779 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase AK38_780 ENOG4105C26 Dehydrogenase AK38_783 ENOG4108V8F Transcriptional regulator, MarR family AK38_784 ENOG4105EE5 Membrane protein terC AK38_785 ENOG4105DAS pts system AK38_786 ENOG4105ETZ PTS System AK38_787 ENOG4105F3R pts system mannose fructose sorbose family iid AK38_79 ENOG4108IPT Naphthoate synthase AK38_791 ENOG4105BZU Histidine kinase AK38_796 ENOG4105DHI Methyltransferase AK38_797 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AK38_801 ENOG4105C85 amino acid AK38_804 ENOG41064PC AK38_805 ENOG4105TIK AK38_806 ENOG4105N4N Protein of unknown function (DUF2766) AK38_81 ENOG4105CEY Amp-dependent synthetase and ligase AK38_810 ENOG4105BZ1 (ABC) transporter AK38_82 ENOG4108MTB glycosyl transferase family AK38_822 ENOG4105M5J Cupin 2, conserved barrel domain protein AK38_824 ENOG4105CHR reductase AK38_825 ENOG41061NF Pectate lyase AK38_826 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component AK38_827 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component AK38_829 ENOG4105WEM extracellular solute-binding protein AK38_83 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AK38_830 ENOG4108PU9 oligogalacturonate-specific porin AK38_831 ENOG4107K5X Membrane-bound metal-dependent hydrolase AK38_832 ENOG4108ETY sodium dicarboxylate symporter AK38_833 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AK38_835 ENOG4105CAZ oligogalacturonide lyase AK38_836 ENOG4105C0R drug resistance transporter emrb qaca subfamily AK38_837 ENOG4108VEV chaperone AK38_840 ENOG4108VEV chaperone AK38_841 ENOG4105H8W Fimbrial protein AK38_844 ENOG4105CN1 protease AK38_846 ENOG4108ZGC gaf domain protein AK38_847 ENOG4105H2K paraquat-inducible protein a AK38_848 ENOG4105DY2 Paraquat-inducible protein b AK38_852 ENOG4105GQR Chaperone AK38_855 ENOG4105WT8 Protein of unknown function (DUF1480) AK38_865 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AK38_868 ENOG4105EUR Domain-Containing protein AK38_869 ENOG4105EUR Domain-Containing protein AK38_87 ENOG4107SDU Methyl-accepting chemotaxis AK38_870 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AK38_871 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) AK38_872 ENOG4108VYJ response regulator receiver protein AK38_874 ENOG4105BZU Histidine kinase AK38_877 ENOG4105C8Q Methyl-accepting chemotaxis AK38_88 ENOG4105CDA abc transporter atp-binding protein AK38_881 ENOG4105WWK YheO domain protein AK38_883 ENOG4105KME endoribonuclease L-psp AK38_884 ENOG4105R9B Major Facilitator AK38_885 ENOG4108V3W Chemotaxis protein, CheW AK38_886 ENOG4105CBS Chea signal transduction histidine kinase AK38_887 ENOG4105ER2 Ompa motb domain protein AK38_888 ENOG4107RD7 Flagellar Motor Protein, MotA AK38_889 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region AK38_89 ENOG4105E5Q amino acid AbC transporter AK38_891 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic AK38_892 ENOG4105KT7 mgtC SapB transporter AK38_893 ENOG4105C8Q Methyl-accepting chemotaxis AK38_894 ENOG4105C8Q Methyl-accepting chemotaxis AK38_899 ENOG4105GSJ Inner membrane protein ylaC AK38_9 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) AK38_90 ENOG4107R0W ABC transporter AK38_900 ENOG4108XM1 transcriptional regulator AsnC family AK38_902 ENOG41061EV selenium-binding protein YdfZ AK38_903 ENOG4105D6F Phosphatase AK38_905 ENOG4105KVH Transcriptional regulator AK38_906 ENOG4105ECR NmrA family AK38_907 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AK38_909 ENOG4106NDP Transcriptional regulator AK38_910 ENOG4108HMX isocitrate dehydrogenase (NADP) AK38_911 ENOG4108R99 pseudouridine synthase AK38_915 ENOG4107QTF adenylosuccinate lyase AK38_917 ENOG4105XJC Two component transcriptional regulator (Winged helix family AK38_919 ENOG4105EZE Cupin 4 family protein AK38_922 ENOG4105EZX Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity) AK38_923 ENOG4105D60 lipoprotein releasing system transmembrane protein AK38_925 ENOG4105D60 lipoprotein releasing system transmembrane protein AK38_926 ENOG4108JA2 transcriptioN-repair coupling factor AK38_927 ENOG4107MBR 17 kDa surface antigen AK38_933 ENOG4105CEP NADH dehydrogenase AK38_935 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) AK38_938 ENOG41090DQ Lipoprotein AK38_939 ENOG4105K59 histidine triad (HIT) protein AK38_940 ENOG4105F9E Shikimate 5-dehydrogenase AK38_941 ENOG4108RS6 transposase AK38_942 ENOG4105CI1 PTS System AK38_943 ENOG4105F8V Hydrolase, tatD family AK38_944 ENOG4107QRG dna polymerase iii AK38_946 ENOG4105HHA aminodeoxychorismate lyase AK38_947 ENOG4105YAZ 4-amino-4-deoxychorismate lyase AK38_948 ENOG4108RS6 transposase AK38_949 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_951 ENOG4105CHR reductase AK38_952 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AK38_955 ENOG4105VGS 50s ribosomal protein l32 AK38_956 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein AK38_957 ENOG4108UHJ MAF-like protein AK38_958 ENOG4108RS6 transposase AK38_959 ENOG4105EI2 Pseudouridine synthase AK38_96 ENOG4108T1M outer membrane protein x AK38_960 ENOG4107QQB Ribonuclease E AK38_962 ENOG41067V3 Antibiotic biosynthesis monooxygenase AK38_966 ENOG4105PVA Biofilm formation regulatory protein BssS AK38_967 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) AK38_971 ENOG4108TSE Transferase AK38_972 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AK38_974 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AK38_975 ENOG4108KX4 response regulator AK38_977 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme AK38_981 ENOG4105UQX Mate efflux family protein AK38_985 ENOG4105DIA mandelate racemase muconate lactonizing AK38_987 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr AK38_988 ENOG4105KIR Thiol-disulfide oxidoreductase dcc AK38_989 ENOG4105CSP Major Facilitator Superfamily AK38_991 ENOG4105TNG K13735 adhesin invasin AK38_994 ENOG4105CJB Exodeoxyribonuclease I AK38_995 ENOG4105CUB amino acid AK38_997 ENOG4107SCQ Iron-containing alcohol dehydrogenase AK38_998 ENOG4105C2J ABC transporter AK38_999 ENOG4105C2J ABC transporter