locus-tag	class	description
AK38_10	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AK38_100	COG1063	alcohol dehydrogenase
AK38_1000	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_1002	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AK38_1004	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AK38_1006	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AK38_1006	COG0131	Imidazoleglycerol-phosphate dehydratase
AK38_101	COG1879	ABC-type sugar transport system periplasmic component
AK38_1010	COG0140	phosphoribosyl-ATP diphosphatase activity
AK38_1010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AK38_1012	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AK38_1013	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AK38_1016	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AK38_1017	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AK38_1018	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AK38_1019	COG1120	ATPase activity
AK38_102	COG1129	ABC transporter
AK38_1022	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AK38_1023	COG0076	glutamate decarboxylase activity
AK38_1024	COG4114	ferric iron reductase
AK38_1025	COG1253	flavin adenine dinucleotide binding
AK38_1026	COG2982	Protein involved in outer membrane biogenesis
AK38_1029	COG0489	protein tyrosine kinase activity
AK38_103	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_1037	COG2814	Major facilitator Superfamily
AK38_1039	COG1346	cytolysis
AK38_104	COG1609	Transcriptional regulator
AK38_1042	COG2949	membrane
AK38_1043	COG4211	Belongs to the binding-protein-dependent transport system permease family
AK38_1046	COG2311	Membrane
AK38_1048	COG0477	Major facilitator Superfamily
AK38_1049	COG0583	DNA-binding transcription factor activity
AK38_105	COG0583	DNA-binding transcription factor activity
AK38_1055	COG1136	(ABC) transporter
AK38_1057	COG0303	'Molybdopterin
AK38_1059	COG3328	transposase activity
AK38_106	COG0473	3-isopropylmalate dehydrogenase activity
AK38_1061	COG0488	(ABC) transporter
AK38_107	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AK38_108	COG4638	Rieske (2fe-2S)
AK38_1088	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AK38_1089	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AK38_109	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AK38_1091	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_1092	COG1024	Enoyl-CoA hydratase
AK38_1094	COG3425	synthase
AK38_1095	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_1096	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AK38_1097	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AK38_1099	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_110	COG2831	hemolysin activation secretion protein
AK38_1106	COG2920	part of a sulfur-relay system
AK38_111	COG3210	domain, Protein
AK38_1110	COG1832	CoA-binding protein
AK38_1113	COG0210	DNA helicase
AK38_1114	COG3304	Inner membrane component domain
AK38_1115	COG1289	transmembrane transporter activity
AK38_1116	COG3070	regulator of competence-specific genes
AK38_1121	COG1067	ATP-dependent peptidase activity
AK38_1124	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AK38_1128	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AK38_1130	COG3009	Protein conserved in bacteria
AK38_1131	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AK38_1131	COG3008	intermembrane lipid transfer
AK38_1132	COG2995	paraquat-inducible protein a
AK38_1133	COG0488	(ABC) transporter
AK38_1135	COG3217	Mosc domain protein beta barrel domain protein
AK38_1135	COG0633	Ferredoxin
AK38_1138	COG0308	aminopeptidase N
AK38_114	COG3210	domain, Protein
AK38_1142	COG1448	Aminotransferase
AK38_1143	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AK38_1144	COG3108	Peptidase M15
AK38_1145	COG2989	Protein conserved in bacteria
AK38_1150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AK38_1151	COG3173	Aminoglycoside phosphotransferase
AK38_1154	COG1278	Cold shock
AK38_1155	COG5383	Protein conserved in bacteria
AK38_1158	COG2333	competence protein COMEC
AK38_1158	COG0658	competence protein
AK38_1161	COG0539	negative regulation of cytoplasmic translation
AK38_1166	COG5295	Hep Hag repeat protein
AK38_1166	COG5295	Hep Hag repeat protein
AK38_1167	COG0252	asparaginase activity
AK38_1168	COG1944	ATP diphosphatase activity
AK38_1169	COG2116	formate transmembrane transporter activity
AK38_117	COG3210	domain, Protein
AK38_1170	COG1882	Formate acetyltransferase
AK38_1172	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AK38_1175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AK38_1178	COG1674	ftsk spoiiie
AK38_1178	COG3107	peptidoglycan biosynthetic process
AK38_1180	COG0492	ferredoxin-NADP+ reductase activity
AK38_1182	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AK38_1184	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AK38_1186	COG0542	response to heat
AK38_1188	COG1278	Cold shock
AK38_119	COG3842	ATPase activity
AK38_1190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AK38_1191	COG2990	Protein conserved in bacteria
AK38_1192	COG3593	DNA synthesis involved in DNA repair
AK38_1193	COG2431	L-lysine efflux transmembrane transporter activity
AK38_1195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AK38_1196	COG0028	Belongs to the TPP enzyme family
AK38_1197	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AK38_1198	COG0702	epimerase
AK38_1199	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AK38_1201	COG1605	Chorismate mutase
AK38_1202	COG1126	abc transporter atp-binding protein
AK38_1203	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AK38_1204	COG4215	(ABC) transporter
AK38_1205	COG4160	amino acid transport
AK38_1209	COG1120	ATPase activity
AK38_121	COG1609	Transcriptional regulator
AK38_1210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AK38_1215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AK38_1218	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AK38_1221	COG1177	transmembrane transport
AK38_1222	COG1176	ABC-type spermidine putrescine transport system, permease component I
AK38_1223	COG3842	ATPase activity
AK38_1224	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AK38_1230	COG0671	phosphoesterase, PA-phosphatase related
AK38_1232	COG1349	DNA-binding transcription factor activity
AK38_1233	COG0814	amino acid
AK38_1234	COG1686	Belongs to the peptidase S11 family
AK38_1235	COG2011	ABC-type metal ion transport system permease component
AK38_124	COG0395	ABC-type sugar transport system, permease component
AK38_1240	COG0625	glutathione transferase activity
AK38_1241	COG4771	TonB-dependent receptor
AK38_1243	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AK38_1245	COG0833	amino acid
AK38_1247	COG0583	DNA-binding transcription factor activity
AK38_1248	COG2855	membrane
AK38_125	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AK38_1250	COG3188	usher protein
AK38_1251	COG3121	Chaperone
AK38_1254	COG3710	Transcriptional regulator
AK38_1255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AK38_1255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AK38_1255	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AK38_1256	COG1105	Belongs to the carbohydrate kinase PfkB family
AK38_1258	COG0494	nUDIX hydrolase
AK38_1260	COG1129	ABC transporter
AK38_1267	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_1272	COG0246	Mannitol dehydrogenase
AK38_1273	COG2186	Transcriptional regulator
AK38_1275	COG0523	cobalamin synthesis protein
AK38_1276	COG0671	phosphoesterase, PA-phosphatase related
AK38_1277	COG0791	NLP P60 protein
AK38_1279	COG2200	EAL domain
AK38_1280	COG4166	transmembrane transport
AK38_1281	COG4174	ABC transporter (Permease)
AK38_1282	COG4239	(ABC) transporter, permease
AK38_1283	COG4172	Belongs to the ABC transporter superfamily
AK38_1285	COG2814	Major facilitator Superfamily
AK38_1286	COG1187	pseudouridine synthase activity
AK38_1287	COG1061	Type III restriction enzyme res subunit
AK38_129	COG0668	transmembrane transport
AK38_1291	COG3082	Protein of unknown function (DUF1414)
AK38_1292	COG3083	sulfuric ester hydrolase activity
AK38_1295	COG3157	Type VI secretion system effector, Hcp
AK38_1299	COG2723	6-phospho-beta-galactosidase activity
AK38_13	COG2197	response regulator
AK38_130	COG1518	maintenance of DNA repeat elements
AK38_1301	COG1737	Transcriptional regulator
AK38_1305	COG3299	homolog of phage Mu protein gp47
AK38_131	COG1203	CRISPR-associated helicase, Cas3
AK38_1313	COG4386	tail sheath protein
AK38_1317	COG3622	Belongs to the hyi family
AK38_1318	COG1349	DNA-binding transcription factor activity
AK38_1319	COG0235	Class ii aldolase
AK38_1320	COG3395	kinase activity
AK38_1328	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AK38_1335	COG2223	nitrite transmembrane transporter activity
AK38_1336	COG0642	Histidine kinase
AK38_1336	COG2198	Histidine kinase
AK38_1337	COG0642	Histidine kinase
AK38_1337	COG2198	Histidine kinase
AK38_1339	COG0784	Response regulator, receiver
AK38_1339	COG2205	protein histidine kinase activity
AK38_1344	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AK38_1347	COG0814	amino acid
AK38_1352	COG0697	spore germination
AK38_1354	COG1982	Orn Lys Arg decarboxylase major
AK38_1355	COG0531	amino acid
AK38_1356	COG1174	glycine betaine transport
AK38_1357	COG1125	glycine betaine transport
AK38_1358	COG1174	glycine betaine transport
AK38_136	COG0667	Aldo Keto reductase
AK38_1361	COG2897	thiosulfate sulfurtransferase activity
AK38_1365	COG1122	ATPase activity
AK38_1369	COG4807	Protein conserved in bacteria
AK38_1372	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AK38_1374	COG2261	transglycosylase associated protein
AK38_1378	COG0277	FAD linked oxidase domain protein
AK38_1379	COG1686	Belongs to the peptidase S11 family
AK38_138	COG0477	Major facilitator Superfamily
AK38_1381	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AK38_1384	COG2211	Major facilitator Superfamily
AK38_1385	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AK38_1387	COG0583	DNA-binding transcription factor activity
AK38_1388	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AK38_1393	COG0670	Belongs to the BI1 family
AK38_1394	COG0314	molybdopterin synthase activity
AK38_1395	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AK38_1397	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AK38_1399	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AK38_140	COG0583	DNA-binding transcription factor activity
AK38_1400	COG4628	conserved protein (DUF2132)
AK38_1402	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AK38_1404	COG2226	methyltransferase
AK38_1409	COG0561	phosphatase activity
AK38_141	COG3916	Acyl-homoserine-lactone synthase
AK38_1411	COG4149	molybdate abc transporter
AK38_1412	COG0725	ABC transporter, periplasmic molybdate-binding protein
AK38_1414	COG2005	Transcriptional regulator
AK38_1414	COG3585	molybdate ion transport
AK38_1415	COG1119	ATPase activity
AK38_1418	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AK38_1419	COG1085	galactose-1-phosphate uridylyltransferase
AK38_142	COG2771	luxR family
AK38_1422	COG2017	converts alpha-aldose to the beta-anomer
AK38_1427	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AK38_1429	COG1230	cation diffusion facilitator family transporter
AK38_1435	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AK38_1436	COG2885	chlorophyll binding
AK38_1438	COG3064	Membrane
AK38_1438	COG3064	Membrane
AK38_1439	COG0848	biopolymer transport protein
AK38_1440	COG0811	peptide transport
AK38_1441	COG0824	Thioesterase
AK38_1442	COG3790	cyd operon protein YbgE
AK38_1443	COG4890	Cyd operon protein YbgT
AK38_1444	COG1294	oxidase, subunit
AK38_1445	COG1271	oxidase subunit
AK38_1446	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AK38_1448	COG0508	dehydrogenase complex catalyzes the overall conversion of
AK38_1449	COG0567	Dehydrogenase, E1 component
AK38_1451	COG1053	succinate dehydrogenase
AK38_1452	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AK38_1453	COG2009	succinate dehydrogenase
AK38_1456	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AK38_1457	COG0497	DNA recombination
AK38_1458	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AK38_146	COG0628	permease
AK38_1460	COG2867	negative regulation of translational initiation
AK38_1463	COG0582	viral genome integration into host DNA
AK38_1473	COG3657	addiction module killer protein
AK38_1480	COG1953	Uracil, thiamine, allantoin
AK38_1484	COG2226	methyltransferase
AK38_1485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AK38_1486	COG0741	lytic transglycosylase activity
AK38_1486	COG1388	LysM domain
AK38_1489	COG0656	L-ascorbic acid biosynthetic process
AK38_149	COG3328	transposase activity
AK38_1495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AK38_1497	COG2011	ABC-type metal ion transport system permease component
AK38_1498	COG1464	Belongs to the NlpA lipoprotein family
AK38_150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AK38_1500	COG1720	tRNA m6t6A37 methyltransferase activity
AK38_1502	COG3015	lipoprotein NlpE involved in copper resistance
AK38_1504	COG4681	YaeQ
AK38_1506	COG4568	rho-dependent transcription termination
AK38_1508	COG0037	tRNA processing
AK38_1509	COG0346	lactoylglutathione lyase activity
AK38_1511	COG0587	DNA-directed DNA polymerase activity
AK38_1516	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AK38_1519	COG0750	zinc metalloprotease
AK38_152	COG3001	Fructosamine kinase
AK38_1520	COG0575	Belongs to the CDS family
AK38_153	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AK38_1532	COG0564	pseudouridine synthase activity
AK38_1533	COG3098	single-species biofilm formation
AK38_1537	COG1611	Belongs to the LOG family
AK38_154	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AK38_1540	COG2363	Small membrane protein
AK38_1541	COG0583	DNA-binding transcription factor activity
AK38_1543	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AK38_1544	COG2166	iron-sulfur cluster assembly
AK38_1545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AK38_1546	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AK38_1549	COG0860	N-Acetylmuramoyl-L-alanine amidase
AK38_155	COG1121	(ABC) transporter
AK38_1551	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AK38_1552	COG1074	ATP-dependent DNA helicase activity
AK38_1554	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AK38_156	COG0803	Belongs to the bacterial solute-binding protein 9 family
AK38_1561	COG4771	TonB-dependent receptor
AK38_1562	COG2195	Cleaves the N-terminal amino acid of tripeptides
AK38_1563	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AK38_1571	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AK38_1573	COG5001	Diguanylate cyclase
AK38_1574	COG2801	Transposase and inactivated derivatives
AK38_1576	COG2211	Major facilitator Superfamily
AK38_1586	COG3916	Acyl-homoserine-lactone synthase
AK38_1587	COG2771	luxR family
AK38_160	COG4249	Peptidase C14 caspase catalytic subunit p20
AK38_1612	COG1982	Orn Lys Arg decarboxylase major
AK38_1613	COG1879	ABC-type sugar transport system periplasmic component
AK38_1614	COG1129	ABC transporter
AK38_1615	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_1616	COG4774	siderophore transport
AK38_1620	COG1194	a g-specific adenine glycosylase
AK38_1622	COG3171	Protein conserved in bacteria
AK38_1626	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AK38_1626	COG1073	alpha beta
AK38_1626	COG3064	Membrane
AK38_1627	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AK38_1628	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AK38_1630	COG0762	integral membrane protein
AK38_1631	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AK38_1632	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AK38_1633	COG2805	Type II/IV secretion system protein
AK38_1635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AK38_1638	COG0189	ligase activity
AK38_1639	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AK38_1640	COG2356	endonuclease I
AK38_1641	COG3091	SprT-like family
AK38_1644	COG1166	arginine decarboxylase activity
AK38_1646	COG0501	Belongs to the peptidase M48B family
AK38_1647	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AK38_1653	COG0191	fructose-bisphosphate aldolase activity
AK38_1659	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AK38_166	COG0072	phenylalanine-tRNA ligase activity
AK38_166	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AK38_1660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AK38_1663	COG0006	proline dipeptidase activity
AK38_1664	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AK38_1665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AK38_167	COG0776	regulation of translation
AK38_1671	COG5295	Hep Hag repeat protein
AK38_1673	COG1272	protein, Hemolysin III
AK38_1677	COG0745	RESPONSE REGULATOR receiver
AK38_1678	COG2205	protein histidine kinase activity
AK38_1679	COG4452	Inner membrane protein CreD
AK38_1680	COG0716	FMN binding
AK38_1681	COG4974	Belongs to the 'phage' integrase family
AK38_1682	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AK38_1683	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AK38_1687	COG0582	viral genome integration into host DNA
AK38_1692	COG2944	sequence-specific DNA binding
AK38_170	COG0386	Belongs to the glutathione peroxidase family
AK38_1709	COG1695	Transcriptional regulator
AK38_1710	COG0791	NLP P60 protein
AK38_1712	COG1879	ABC-type sugar transport system periplasmic component
AK38_1713	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_1714	COG1129	ABC transporter
AK38_1716	COG2182	Extracellular solute-binding protein
AK38_1717	COG1175	transmembrane transport
AK38_1718	COG3833	ABC-type maltose transport systems, permease component
AK38_1719	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AK38_1720	COG1874	Beta-galactosidase
AK38_1721	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AK38_1721	COG1263	PTS System
AK38_1725	COG2271	Major facilitator Superfamily
AK38_1731	COG3119	arylsulfatase activity
AK38_1732	COG0641	radical SAM
AK38_1734	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_1736	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AK38_1737	COG3716	PTS system mannose fructose sorbose family IID component
AK38_1738	COG3715	PTS system
AK38_1739	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AK38_1740	COG2222	sugar isomerase
AK38_1742	COG1349	DNA-binding transcription factor activity
AK38_1743	COG3119	arylsulfatase activity
AK38_1752	COG0288	reversible hydration of carbon dioxide
AK38_1771	COG0840	transmembrane signaling receptor activity
AK38_1773	COG0583	DNA-binding transcription factor activity
AK38_1774	COG0583	DNA-binding transcription factor activity
AK38_1775	COG2814	Major facilitator Superfamily
AK38_1776	COG1609	Transcriptional regulator
AK38_1783	COG0667	Aldo Keto reductase
AK38_179	COG0791	NLP P60 protein
AK38_1794	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AK38_1794	COG3433	isochorismatase activity
AK38_1794	COG2226	methyltransferase
AK38_1796	COG3433	isochorismatase activity
AK38_1796	COG2226	methyltransferase
AK38_1796	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AK38_18	COG5265	(ABC) transporter
AK38_1802	COG1132	(ABC) transporter
AK38_1806	COG2610	gluconate transmembrane transporter activity
AK38_1809	COG3501	Rhs element vgr protein
AK38_1811	COG3209	COG3209 Rhs family protein
AK38_1814	COG0471	metal ion transport
AK38_1816	COG2801	Transposase and inactivated derivatives
AK38_1818	COG3133	Outer membrane lipoprotein
AK38_1819	COG3133	Outer membrane lipoprotein
AK38_1824	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AK38_1825	COG1191	sigma factor activity
AK38_1830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AK38_1834	COG3710	Transcriptional regulator
AK38_1838	COG1256	bacterial-type flagellum assembly
AK38_1840	COG1706	bacterial-type flagellum-dependent cell motility
AK38_1842	COG4786	Flagellar basal body rod
AK38_1846	COG1749	Flagellar hook protein flgE
AK38_1847	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AK38_1848	COG1558	bacterial-type flagellum-dependent cell motility
AK38_1849	COG1815	bacterial-type flagellum-dependent cell motility
AK38_185	COG0574	Belongs to the PEP-utilizing enzyme family
AK38_185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AK38_1850	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AK38_1858	COG1677	Flagellar hook-basal body complex protein FliE
AK38_186	COG0628	permease
AK38_1863	COG1987	bacterial-type flagellum assembly
AK38_1864	COG1684	flagellar biosynthetic protein fliR
AK38_1865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AK38_187	COG0277	FAD linked oxidase domain protein
AK38_187	COG0247	lactate metabolic process
AK38_1870	COG4592	Periplasmic binding protein
AK38_1878	COG4964	Belongs to the GSP D family
AK38_1879	COG4964	Belongs to the GSP D family
AK38_188	COG2050	protein possibly involved in aromatic compounds catabolism
AK38_1889	COG0848	biopolymer transport protein
AK38_189	COG0316	Belongs to the HesB IscA family
AK38_1891	COG0811	peptide transport
AK38_1892	COG0626	cystathionine gamma-synthase activity
AK38_1893	COG0586	Pfam SNARE associated Golgi protein
AK38_1894	COG2207	Transcriptional regulator
AK38_1895	COG1979	alcohol dehydrogenase
AK38_1896	COG0656	L-ascorbic acid biosynthetic process
AK38_1899	COG2132	Multicopper oxidase
AK38_190	COG0719	Fe-S assembly protein
AK38_1901	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AK38_1902	COG2249	NAD(P)H dehydrogenase (quinone) activity
AK38_1903	COG0583	DNA-binding transcription factor activity
AK38_1905	COG3150	esterase
AK38_1906	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AK38_1907	COG3151	Protein conserved in bacteria
AK38_1908	COG0494	nUDIX hydrolase
AK38_1909	COG1538	Outer membrane efflux protein
AK38_191	COG0396	ATPase activity
AK38_1912	COG0754	glutathionylspermidine amidase activity
AK38_1913	COG3384	dioxygenase
AK38_1917	COG0531	amino acid
AK38_192	COG0719	Fe-S assembly protein
AK38_1920	COG3025	triphosphatase activity
AK38_1921	COG4991	sh3 domain protein
AK38_1924	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AK38_1927	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AK38_1928	COG0358	DNA primase activity
AK38_1946	COG0251	oxidation-reduction process
AK38_195	COG1388	LysM domain
AK38_195	COG1376	ErfK ybiS ycfS ynhG family protein
AK38_1950	COG0436	Aminotransferase
AK38_1954	COG1289	transmembrane transporter activity
AK38_1958	COG0395	ABC-type sugar transport system, permease component
AK38_1960	COG2182	Extracellular solute-binding protein
AK38_1961	COG1609	Transcriptional regulator
AK38_1962	COG3459	Glycosyltransferase 36 associated
AK38_1963	COG3842	ATPase activity
AK38_1967	COG3210	domain, Protein
AK38_1971	COG3210	domain, Protein
AK38_1972	COG2831	hemolysin activation secretion protein
AK38_1973	COG4245	von Willebrand factor, type A
AK38_1976	COG4245	von Willebrand factor, type A
AK38_1979	COG3247	response to pH
AK38_1980	COG1902	pentaerythritol trinitrate reductase activity
AK38_1980	COG0446	pyridine nucleotide-disulphide oxidoreductase
AK38_1983	COG1451	nucleotide metabolic process
AK38_1984	COG0673	inositol 2-dehydrogenase activity
AK38_1989	COG2721	sulfolactate sulfo-lyase activity
AK38_1992	COG2271	Major facilitator Superfamily
AK38_1995	COG0586	Pfam SNARE associated Golgi protein
AK38_1998	COG4575	ribosome binding
AK38_1999	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AK38_2	COG0768	penicillin binding
AK38_20	COG3718	enzyme involved in inositol metabolism
AK38_2001	COG2259	Doxx family
AK38_2002	COG0435	Glutathione S-transferase
AK38_2005	COG0494	nUDIX hydrolase
AK38_2010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AK38_2011	COG0849	cell division
AK38_2012	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AK38_2016	COG0772	Belongs to the SEDS family
AK38_2019	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AK38_2020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AK38_2021	COG0768	penicillin binding
AK38_2022	COG3116	cell division
AK38_2026	COG1609	Transcriptional regulator
AK38_2029	COG0028	Belongs to the TPP enzyme family
AK38_2030	COG1022	Amp-dependent synthetase and ligase
AK38_2035	COG0473	3-isopropylmalate dehydrogenase activity
AK38_2038	COG2814	Major facilitator Superfamily
AK38_2041	COG2814	Major facilitator Superfamily
AK38_2044	COG4143	(ABC) transporter
AK38_2045	COG1178	ABC-type Fe3 transport system permease component
AK38_2046	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AK38_2047	COG0586	Pfam SNARE associated Golgi protein
AK38_2048	COG0417	DNA replication proofreading
AK38_2052	COG3047	cAMP biosynthetic process
AK38_2052	COG2885	chlorophyll binding
AK38_2060	COG3501	Rhs element vgr protein
AK38_207	COG0307	riboflavin synthase, alpha
AK38_2070	COG0564	pseudouridine synthase activity
AK38_2071	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AK38_208	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AK38_2080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AK38_2082	COG2966	Psort location CytoplasmicMembrane, score
AK38_2083	COG1280	lysine exporter protein (LysE YggA)
AK38_2084	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AK38_2089	COG1047	Peptidyl-prolyl cis-trans
AK38_209	COG2814	Major facilitator Superfamily
AK38_2092	COG0196	riboflavin kinase activity
AK38_2094	COG0583	DNA-binding transcription factor activity
AK38_2098	COG1584	GPR1 FUN34 yaaH family protein
AK38_210	COG0583	DNA-binding transcription factor activity
AK38_2101	COG0521	Mo-molybdopterin cofactor biosynthetic process
AK38_2109	COG0745	RESPONSE REGULATOR receiver
AK38_2110	COG3045	CreA protein
AK38_2113	COG2207	Transcriptional regulator
AK38_2113	COG3708	Transcriptional regulator
AK38_2114	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AK38_2116	COG0741	lytic transglycosylase activity
AK38_2119	COG2199	diguanylate cyclase activity
AK38_2120	COG2885	chlorophyll binding
AK38_2121	COG0488	(ABC) transporter
AK38_2122	COG0488	(ABC) transporter
AK38_2126	COG0560	Phosphoserine phosphatase
AK38_2127	COG3726	membrane protein affecting hemolysin expression
AK38_2133	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AK38_2134	COG0084	hydrolase, TatD family'
AK38_2135	COG4667	esterase of the alpha-beta hydrolase superfamily
AK38_2137	COG2823	Periplasmic or secreted lipoprotein
AK38_2139	COG0456	acetyltransferase
AK38_214	COG0791	NLP P60 protein
AK38_2140	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AK38_2144	COG3706	GGDEF domain
AK38_2147	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AK38_2148	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AK38_2151	COG0859	PFAM glycosyl transferase family 9
AK38_2152	COG1070	Carbohydrate kinase
AK38_2153	COG2390	Transcriptional regulator
AK38_2154	COG2390	Transcriptional regulator
AK38_216	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AK38_2162	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AK38_2162	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AK38_2162	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AK38_2163	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AK38_2164	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AK38_2165	COG2207	Transcriptional regulator
AK38_2166	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AK38_2168	COG4269	membrane
AK38_217	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AK38_2178	COG2963	transposase activity
AK38_218	COG0346	lactoylglutathione lyase activity
AK38_2180	COG1401	restriction endodeoxyribonuclease activity
AK38_2184	COG3650	response to hydrogen peroxide
AK38_2185	COG1960	acyl-CoA dehydrogenase activity
AK38_2186	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AK38_2187	COG0557	exoribonuclease II activity
AK38_2190	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AK38_2191	COG0330	HflC and HflK could
AK38_2192	COG0330	HflC and HflK could
AK38_2193	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AK38_2197	COG0860	N-Acetylmuramoyl-L-alanine amidase
AK38_2198	COG0802	atpase or kinase
AK38_2199	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AK38_2199	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AK38_22	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AK38_220	COG1902	pentaerythritol trinitrate reductase activity
AK38_2200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AK38_2203	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AK38_2206	COG3264	Mechanosensitive ion channel
AK38_2206	COG1511	domain protein
AK38_2208	COG1053	succinate dehydrogenase
AK38_2209	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AK38_221	COG1309	transcriptional regulator
AK38_2211	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AK38_222	COG2194	sulfuric ester hydrolase activity
AK38_2221	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AK38_2224	COG3383	formate dehydrogenase (NAD+) activity
AK38_2225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AK38_2226	COG0493	'glutamate synthase
AK38_2226	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AK38_2227	COG1309	transcriptional regulator
AK38_223	COG3313	Fe-S protein
AK38_224	COG4989	oxidoreductase activity
AK38_2241	COG1454	alcohol dehydrogenase
AK38_2243	COG0629	single-stranded DNA binding
AK38_2244	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AK38_2245	COG2315	Protein conserved in bacteria
AK38_2246	COG1448	Aminotransferase
AK38_2251	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AK38_2252	COG0735	belongs to the Fur family
AK38_2254	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AK38_226	COG3133	Outer membrane lipoprotein
AK38_2262	COG3121	Chaperone
AK38_2275	COG1358	cellular component organization or biogenesis
AK38_228	COG3895	Periplasmic Protein
AK38_2280	COG3721	Heme iron utilization protein
AK38_2281	COG0702	epimerase
AK38_2282	COG4771	TonB-dependent receptor
AK38_2283	COG3720	iron ion transport
AK38_2284	COG4558	Periplasmic binding protein
AK38_2285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AK38_2287	COG0626	cystathionine gamma-synthase activity
AK38_2288	COG0814	amino acid
AK38_2289	COG0583	DNA-binding transcription factor activity
AK38_2290	COG0425	Belongs to the sulfur carrier protein TusA family
AK38_2291	COG2391	methyltransferase activity
AK38_23	COG0673	inositol 2-dehydrogenase activity
AK38_2313	COG1301	dicarboxylic acid transport
AK38_2315	COG3162	membrane
AK38_232	COG0625	glutathione transferase activity
AK38_2320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AK38_2323	COG0551	DNA topoisomerase type I activity
AK38_2325	COG0758	DNA mediated transformation
AK38_2331	COG3036	rescue of stalled ribosome
AK38_2332	COG0789	Transcriptional regulator
AK38_2335	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AK38_2338	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AK38_2339	COG0201	protein transport
AK38_2341	COG1841	ribosomal large subunit assembly
AK38_2349	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AK38_2350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AK38_2352	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AK38_2353	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AK38_2355	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AK38_2357	COG0089	rRNA binding
AK38_2360	COG0051	transcription antitermination factor activity, RNA binding
AK38_2366	COG0049	tRNA binding
AK38_2367	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AK38_237	COG3104	oligopeptide transport
AK38_2371	COG2964	Protein conserved in bacteria
AK38_2372	COG0545	Peptidyl-prolyl cis-trans isomerase
AK38_2374	COG1047	Peptidyl-prolyl cis-trans
AK38_2375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AK38_2378	COG0488	(ABC) transporter
AK38_2379	COG0488	(ABC) transporter
AK38_2380	COG1216	Glycosyl transferase, family 2
AK38_2382	COG2175	clavaminate synthase activity
AK38_2383	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AK38_2385	COG4521	taurine ABC transporter
AK38_2387	COG0429	hydrolase of the alpha beta-hydrolase fold
AK38_2389	COG3954	Phosphoribulokinase
AK38_239	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AK38_239	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AK38_2391	COG1765	OsmC-like protein
AK38_2393	COG1289	transmembrane transporter activity
AK38_24	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_240	COG4172	Belongs to the ABC transporter superfamily
AK38_2400	COG0433	COG0433 Predicted ATPase
AK38_2401	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AK38_2402	COG1486	melibiose metabolic process
AK38_2406	COG0402	S-adenosylhomocysteine deaminase activity
AK38_2407	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AK38_2411	COG0180	Tryptophanyl-tRNA synthetase
AK38_2412	COG0546	phosphoglycolate phosphatase activity
AK38_2413	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AK38_2418	COG4796	Type ii and iii secretion system protein
AK38_242	COG4171	peptide transport system, permease
AK38_2423	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AK38_2424	COG0494	nUDIX hydrolase
AK38_2427	COG1011	Hydrolase
AK38_2428	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AK38_243	COG4168	peptide transport system, permease
AK38_2432	COG0745	RESPONSE REGULATOR receiver
AK38_2433	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AK38_2434	COG2183	response to ionizing radiation
AK38_2435	COG1918	ferrous iron import across plasma membrane
AK38_244	COG4166	transmembrane transport
AK38_2442	COG1640	4-alpha-glucanotransferase
AK38_2443	COG0058	SHG alpha-glucan phosphorylase activity
AK38_2444	COG0058	SHG alpha-glucan phosphorylase activity
AK38_2446	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AK38_2448	COG1349	DNA-binding transcription factor activity
AK38_2450	COG2801	Transposase and inactivated derivatives
AK38_2452	COG0527	aspartate kinase activity
AK38_2452	COG0460	homoserine dehydrogenase
AK38_2453	COG0626	cystathionine gamma-synthase activity
AK38_2454	COG0626	cystathionine gamma-synthase activity
AK38_2456	COG4682	membrane
AK38_2458	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AK38_246	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AK38_2460	COG1609	Transcriptional regulator
AK38_2461	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AK38_2464	COG1575	Belongs to the MenA family. Type 1 subfamily
AK38_247	COG1842	Phage shock protein A
AK38_2475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AK38_2476	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AK38_2477	COG1494	fructose-1,6-bisphosphatase
AK38_2479	COG3152	Membrane
AK38_2482	COG0583	DNA-binding transcription factor activity
AK38_2483	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AK38_2484	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AK38_2485	COG0471	metal ion transport
AK38_2487	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AK38_249	COG1983	PspC domain protein
AK38_2492	COG3678	ATP-independent chaperone mediated protein folding
AK38_2493	COG0745	RESPONSE REGULATOR receiver
AK38_2494	COG2205	protein histidine kinase activity
AK38_2495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AK38_2495	COG2169	Transcriptional regulator
AK38_2496	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AK38_2497	COG1045	serine acetyltransferase
AK38_25	COG1129	ABC transporter
AK38_2500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AK38_2501	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AK38_2503	COG4942	peptidase
AK38_2504	COG2861	carbohydrate metabolic process
AK38_2505	COG2861	carbohydrate metabolic process
AK38_2507	COG0156	8-amino-7-oxononanoate synthase activity
AK38_2509	COG0859	PFAM glycosyl transferase family 9
AK38_251	COG3106	COG3106 Predicted ATPase
AK38_2510	COG0859	PFAM glycosyl transferase family 9
AK38_2511	COG1519	Transferase
AK38_2518	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AK38_2523	COG1561	YicC-like family, N-terminal region
AK38_2524	COG2860	membrane
AK38_2528	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AK38_2529	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AK38_253	COG5654	RES domain protein
AK38_2530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AK38_2531	COG0786	glutamate:sodium symporter activity
AK38_2532	COG2233	PERMEase
AK38_2533	COG2982	Protein involved in outer membrane biogenesis
AK38_2534	COG0456	acetyltransferase
AK38_2539	COG1011	Hydrolase
AK38_254	COG5642	Protein of unknown function (DUF2384)
AK38_2541	COG0174	glutamine synthetase
AK38_2542	COG3852	Histidine kinase
AK38_2544	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AK38_2548	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AK38_2548	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AK38_2549	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AK38_2550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AK38_2551	COG3084	Protein conserved in bacteria
AK38_2553	COG1763	Mo-molybdopterin cofactor biosynthetic process
AK38_2554	COG3328	transposase activity
AK38_2559	COG2186	Transcriptional regulator
AK38_2561	COG0477	Major facilitator Superfamily
AK38_2562	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AK38_2568	COG1522	sequence-specific DNA binding
AK38_2569	COG0716	FMN binding
AK38_257	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AK38_2572	COG3312	ion transport
AK38_258	COG4948	Mandelate Racemase Muconate Lactonizing
AK38_2583	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AK38_2584	COG0573	inorganic phosphate transmembrane transporter activity
AK38_2585	COG0581	inorganic phosphate transmembrane transporter activity
AK38_2587	COG0704	Plays a role in the regulation of phosphate uptake
AK38_2589	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AK38_259	COG2866	Carboxypeptidase
AK38_2590	COG0765	amino acid transport
AK38_2591	COG0765	amino acid transport
AK38_2592	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AK38_2593	COG2252	PERMEase
AK38_2598	COG0706	membrane insertase activity
AK38_260	COG4166	transmembrane transport
AK38_2601	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AK38_2604	COG0592	DNA-directed DNA polymerase activity
AK38_2606	COG0187	DNA topoisomerase II activity
AK38_2607	COG0561	phosphatase activity
AK38_2608	COG2801	Transposase and inactivated derivatives
AK38_2611	COG2423	ornithine cyclodeaminase activity
AK38_2612	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AK38_2613	COG0823	Involved in the tonB-independent uptake of proteins
AK38_2614	COG0823	Involved in the tonB-independent uptake of proteins
AK38_2615	COG5645	(Lipo)protein
AK38_2619	COG3977	Valine--pyruvate aminotransferase
AK38_2621	COG0366	Alpha amylase catalytic
AK38_2624	COG2885	chlorophyll binding
AK38_2626	COG2818	Glycosylase
AK38_263	COG2755	lipolytic protein G-D-S-L family
AK38_263	COG0657	acetylesterase activity
AK38_2631	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AK38_2631	COG2213	PTS system mannitol-specific
AK38_2633	COG3722	fumarate hydratase activity
AK38_2640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AK38_2642	COG3383	formate dehydrogenase (NAD+) activity
AK38_2642	COG0243	molybdopterin cofactor binding
AK38_2643	COG3383	formate dehydrogenase (NAD+) activity
AK38_2643	COG0243	molybdopterin cofactor binding
AK38_2644	COG0437	4 iron, 4 sulfur cluster binding
AK38_2645	COG2864	formate dehydrogenase
AK38_2656	COG2801	Transposase and inactivated derivatives
AK38_2658	COG3274	enterobacterial common antigen metabolic process
AK38_266	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AK38_266	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AK38_266	COG1013	pyruvate-flavodoxin oxidoreductase activity
AK38_266	COG0674	pyruvate-flavodoxin oxidoreductase activity
AK38_2660	COG3188	usher protein
AK38_2661	COG3188	usher protein
AK38_2662	COG3121	Chaperone
AK38_2664	COG1070	Carbohydrate kinase
AK38_2666	COG4213	ABC transporter substrate-binding protein
AK38_2668	COG4214	carbohydrate transport
AK38_2669	COG1609	Transcriptional regulator
AK38_2669	COG2207	Transcriptional regulator
AK38_2671	COG0582	viral genome integration into host DNA
AK38_2678	COG4604	ABC transporter, ATP-binding protein
AK38_268	COG1285	pathogenesis
AK38_2680	COG4605	iron ion homeostasis
AK38_2682	COG4607	ABC-type enterochelin transport system periplasmic component
AK38_2688	COG2986	histidine ammonia-lyase
AK38_269	COG3042	response to heat
AK38_2691	COG2194	sulfuric ester hydrolase activity
AK38_2692	COG2197	response regulator
AK38_2693	COG3851	Histidine kinase
AK38_2697	COG2271	Major facilitator Superfamily
AK38_27	COG0673	inositol 2-dehydrogenase activity
AK38_270	COG3187	Heat shock protein
AK38_2701	COG2831	hemolysin activation secretion protein
AK38_2703	COG0747	negative chemotaxis
AK38_2704	COG0601	transmembrane transport
AK38_2705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AK38_2706	COG0444	Belongs to the ABC transporter superfamily
AK38_2707	COG4608	Belongs to the ABC transporter superfamily
AK38_2708	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AK38_2709	COG2200	EAL domain
AK38_2709	COG2199	diguanylate cyclase activity
AK38_271	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AK38_2710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AK38_2715	COG0612	Peptidase, M16
AK38_2716	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AK38_2717	COG1942	4-Oxalocrotonate Tautomerase
AK38_2718	COG2200	EAL domain
AK38_2719	COG2134	cdp-diacylglycerol pyrophosphatase
AK38_272	COG2911	Protein conserved in bacteria
AK38_2720	COG2982	Protein involved in outer membrane biogenesis
AK38_2721	COG1295	ribonuclease BN
AK38_2726	COG1929	Belongs to the glycerate kinase type-1 family
AK38_2727	COG2610	gluconate transmembrane transporter activity
AK38_2728	COG3835	regulator
AK38_2729	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AK38_2730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AK38_2731	COG0339	signal peptide processing
AK38_2735	COG0589	response to stress
AK38_2738	COG0306	phosphate transporter
AK38_2739	COG2081	HI0933 family
AK38_274	COG3784	Protein of unknown function (DUF1318)
AK38_2742	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_2745	COG0191	fructose-bisphosphate aldolase activity
AK38_2747	COG0745	RESPONSE REGULATOR receiver
AK38_2749	COG1741	Belongs to the pirin family
AK38_275	COG0246	Mannitol dehydrogenase
AK38_2750	COG1609	Transcriptional regulator
AK38_2751	COG2610	gluconate transmembrane transporter activity
AK38_2752	COG3265	gluconokinase activity
AK38_2756	COG2095	MarC family integral membrane protein
AK38_2757	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AK38_276	COG2390	Transcriptional regulator
AK38_2763	COG3275	phosphorelay sensor kinase activity
AK38_2768	COG0058	SHG alpha-glucan phosphorylase activity
AK38_2769	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AK38_2772	COG2801	Transposase and inactivated derivatives
AK38_2779	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AK38_278	COG1643	Atp-dependent helicase
AK38_2783	COG1629	transport
AK38_2788	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AK38_2789	COG0678	peroxiredoxin activity
AK38_2789	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AK38_28	COG0673	inositol 2-dehydrogenase activity
AK38_2804	COG1879	ABC-type sugar transport system periplasmic component
AK38_2805	COG1129	ABC transporter
AK38_2806	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_2808	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_2809	COG3085	chromosome segregation
AK38_281	COG3591	Belongs to the peptidase S1B family
AK38_2812	COG3978	acetolactate synthase activity
AK38_2813	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AK38_2822	COG0583	DNA-binding transcription factor activity
AK38_2828	COG3121	Chaperone
AK38_283	COG3038	cytochrome b561
AK38_2831	COG3121	Chaperone
AK38_2833	COG3328	transposase activity
AK38_2835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AK38_2840	COG3118	belongs to the thioredoxin family
AK38_2841	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AK38_2842	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AK38_2843	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AK38_2844	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AK38_2845	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AK38_2846	COG1088	dTDP-glucose 4,6-dehydratase activity
AK38_2847	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AK38_2848	COG0456	acetyltransferase
AK38_2849	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AK38_2850	COG2244	polysaccharide biosynthetic process
AK38_2854	COG1113	amino acid transport
AK38_2861	COG3071	HemY protein
AK38_2862	COG2959	enzyme of heme biosynthesis
AK38_2863	COG1587	Uroporphyrinogen-III synthase
AK38_2865	COG3072	Adenylate cyclase
AK38_2869	COG3159	Protein conserved in bacteria
AK38_287	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AK38_2870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AK38_2871	COG1011	Hydrolase
AK38_2872	COG0210	DNA helicase
AK38_2874	COG5441	Belongs to the UPF0261 family
AK38_2875	COG5564	TIM-barrel signal transduction protein
AK38_2878	COG2050	protein possibly involved in aromatic compounds catabolism
AK38_2879	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AK38_288	COG2205	protein histidine kinase activity
AK38_2880	COG0514	ATP-dependent DNA helicase (RecQ)
AK38_2881	COG1280	lysine exporter protein (LysE YggA)
AK38_2882	COG1280	lysine exporter protein (LysE YggA)
AK38_2883	COG2267	carboxylic ester hydrolase activity
AK38_2884	COG0561	phosphatase activity
AK38_2887	COG0584	glycerophosphoryl diester phosphodiesterase
AK38_2888	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AK38_289	COG0745	RESPONSE REGULATOR receiver
AK38_2890	COG0247	lactate metabolic process
AK38_2892	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AK38_2895	COG3714	YhhN family
AK38_2898	COG3776	membrane
AK38_2899	COG0742	ribosomal rna small subunit methyltransferase
AK38_29	COG3962	Belongs to the TPP enzyme family
AK38_2900	COG0552	protein localization to endoplasmic reticulum
AK38_2900	COG0552	protein localization to endoplasmic reticulum
AK38_2901	COG0552	protein localization to endoplasmic reticulum
AK38_2902	COG2884	Cell division ATP-binding protein ftsE
AK38_2903	COG2177	Part of the ABC transporter FtsEX involved in
AK38_2907	COG0683	leucine binding
AK38_2909	COG4177	L-phenylalanine transmembrane transporter activity
AK38_291	COG0531	amino acid
AK38_2911	COG0410	ABC transporter
AK38_2923	COG0584	glycerophosphoryl diester phosphodiesterase
AK38_2924	COG0679	Auxin Efflux Carrier
AK38_2925	COG0583	DNA-binding transcription factor activity
AK38_2926	COG0697	spore germination
AK38_2928	COG0412	Dienelactone hydrolase
AK38_293	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AK38_2931	COG1966	Carbon starvation protein
AK38_2932	COG0586	Pfam SNARE associated Golgi protein
AK38_2933	COG1322	Protein conserved in bacteria
AK38_2937	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AK38_2939	COG0805	protein transport
AK38_294	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AK38_2946	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AK38_295	COG0589	response to stress
AK38_2951	COG1739	Uncharacterized protein family UPF0029
AK38_2953	COG1739	Uncharacterized protein family UPF0029
AK38_2954	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AK38_2955	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AK38_296	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AK38_2961	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AK38_297	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AK38_2973	COG0250	Participates in transcription elongation, termination and antitermination
AK38_2982	COG2022	thiamine diphosphate biosynthetic process
AK38_2984	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AK38_2991	COG1515	deoxyribonuclease V activity
AK38_2995	COG0151	Belongs to the GarS family
AK38_3	COG0772	Belongs to the SEDS family
AK38_3008	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AK38_3009	COG2224	Isocitrate lyase
AK38_301	COG1011	Hydrolase
AK38_3011	COG1414	Transcriptional regulator
AK38_3012	COG1414	Transcriptional regulator
AK38_3016	COG0527	aspartate kinase activity
AK38_3019	COG3833	ABC-type maltose transport systems, permease component
AK38_302	COG0440	acetolactate synthase activity
AK38_3020	COG1175	transmembrane transport
AK38_303	COG0028	Belongs to the TPP enzyme family
AK38_3031	COG2801	Transposase and inactivated derivatives
AK38_3037	COG1609	Transcriptional regulator
AK38_3038	COG1263	PTS System
AK38_3038	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AK38_3039	COG0366	Alpha amylase catalytic
AK38_3040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AK38_3041	COG3783	Cytochrome b(562)
AK38_3043	COG0312	modulator of DNA gyrase
AK38_3045	COG2732	(Barnase) inhibitor
AK38_3048	COG1012	belongs to the aldehyde dehydrogenase family
AK38_3052	COG0583	DNA-binding transcription factor activity
AK38_3063	COG0312	modulator of DNA gyrase
AK38_3064	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AK38_3065	COG3164	Protein of unknown function
AK38_3066	COG1530	ribonuclease E activity
AK38_3067	COG0424	maF-like protein
AK38_3068	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AK38_3069	COG1792	Involved in formation and maintenance of cell shape
AK38_3070	COG1077	Cell shape determining protein MreB Mrl
AK38_3071	COG2200	EAL domain
AK38_3071	COG2199	diguanylate cyclase activity
AK38_3072	COG0604	alcohol dehydrogenase
AK38_3073	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AK38_3076	COG0511	ligase activity, forming carbon-carbon bonds
AK38_3077	COG0439	Biotin carboxylase
AK38_3079	COG3924	membrane
AK38_308	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AK38_3080	COG4145	pantothenate transmembrane transporter activity
AK38_3082	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AK38_3083	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AK38_3087	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AK38_3089	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AK38_3090	COG3133	Outer membrane lipoprotein
AK38_3091	COG1278	Cold shock
AK38_3092	COG1278	Cold shock
AK38_3096	COG0625	glutathione transferase activity
AK38_3098	COG1069	ribulokinase activity
AK38_3100	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_3101	COG1129	ABC transporter
AK38_3103	COG1560	Kdo2-lipid A biosynthetic process
AK38_3105	COG0025	NhaP-type Na H and K H
AK38_3106	COG2252	PERMEase
AK38_3107	COG3077	Addiction module antitoxin, RelB DinJ family
AK38_3109	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AK38_311	COG1879	ABC-type sugar transport system periplasmic component
AK38_3111	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AK38_3112	COG0431	NADPH-dependent FMN reductase
AK38_3113	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AK38_3114	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AK38_3115	COG1869	D-ribose catabolic process
AK38_3116	COG1917	Cupin 2, conserved barrel domain protein
AK38_3116	COG2207	Transcriptional regulator
AK38_3117	COG0673	inositol 2-dehydrogenase activity
AK38_3120	COG3209	COG3209 Rhs family protein
AK38_3122	COG3501	Rhs element vgr protein
AK38_3128	COG3209	COG3209 Rhs family protein
AK38_313	COG1609	Transcriptional regulator
AK38_3131	COG3501	Rhs element vgr protein
AK38_3151	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AK38_3155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AK38_3156	COG1137	ATPase activity
AK38_3157	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AK38_3158	COG3117	lipopolysaccharide transmembrane transporter activity
AK38_3159	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AK38_3160	COG0517	IMP dehydrogenase activity
AK38_3160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AK38_3161	COG0530	calcium, potassium:sodium antiporter activity
AK38_3162	COG1127	ABC transporter
AK38_3163	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AK38_3164	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AK38_3165	COG2854	intermembrane phospholipid transfer
AK38_3166	COG3113	response to antibiotic
AK38_3167	COG5007	Belongs to the BolA IbaG family
AK38_3169	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AK38_3171	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AK38_3172	COG3105	Protein conserved in bacteria
AK38_3173	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AK38_3176	COG0625	glutathione transferase activity
AK38_3177	COG2969	positive regulation of protein catabolic process
AK38_3179	COG0493	'glutamate synthase
AK38_318	COG4128	Pfam Zonular occludens toxin
AK38_3180	COG0067	glutamate synthase
AK38_3180	COG0069	glutamate synthase activity
AK38_3180	COG0070	glutamate synthase
AK38_3181	COG1242	4 iron, 4 sulfur cluster binding
AK38_3182	COG5002	protein histidine kinase activity
AK38_3182	COG2198	Histidine kinase
AK38_3182	COG0784	Response regulator, receiver
AK38_3183	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AK38_3185	COG2823	Periplasmic or secreted lipoprotein
AK38_3189	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AK38_3190	COG1741	Belongs to the pirin family
AK38_3191	COG0583	DNA-binding transcription factor activity
AK38_3192	COG0435	Glutathione S-transferase
AK38_3195	COG1073	alpha beta
AK38_3197	COG0360	Binds together with S18 to 16S ribosomal RNA
AK38_3198	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AK38_3202	COG3061	Opacity-associated protein A
AK38_3203	COG0545	Peptidyl-prolyl cis-trans isomerase
AK38_3205	COG0737	Belongs to the 5'-nucleotidase family
AK38_3207	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AK38_3209	COG1253	flavin adenine dinucleotide binding
AK38_3211	COG0729	surface antigen
AK38_3214	COG2105	PFAM AIG2 family protein
AK38_3215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AK38_3216	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AK38_3217	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AK38_3221	COG3423	Transcriptional regulator
AK38_3223	COG0142	geranyltranstransferase activity
AK38_3226	COG0697	spore germination
AK38_3228	COG0642	Histidine kinase
AK38_3229	COG0745	RESPONSE REGULATOR receiver
AK38_3230	COG2027	D-alanyl-D-alanine carboxypeptidase
AK38_3232	COG1534	Rna-binding protein
AK38_3235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AK38_3237	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AK38_3241	COG0195	Participates in both transcription termination and antitermination
AK38_3247	COG2801	Transposase and inactivated derivatives
AK38_3250	COG0513	Belongs to the DEAD box helicase family
AK38_3253	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AK38_3256	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AK38_3258	COG0826	peptidase U32
AK38_3259	COG0826	peptidase U32
AK38_3260	COG3154	lipid carrier protein
AK38_3261	COG3153	acetyltransferase
AK38_3265	COG1653	transport
AK38_3266	COG1175	transmembrane transport
AK38_3267	COG0395	ABC-type sugar transport system, permease component
AK38_3268	COG3842	ATPase activity
AK38_3271	COG0702	epimerase
AK38_3272	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AK38_3273	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AK38_3274	COG3454	Phosphonate metabolism
AK38_3275	COG4778	phosphonate C-P lyase system protein PhnL
AK38_3276	COG4107	phosphonate C-P lyase system protein PhnK
AK38_3277	COG3627	carbon phosphorus lyase activity
AK38_3278	COG3626	phosphonate metabolism
AK38_3279	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AK38_3280	COG3624	Phosphonate C-P lyase system protein PhnG
AK38_3281	COG2188	Transcriptional regulator
AK38_3285	COG4608	Belongs to the ABC transporter superfamily
AK38_3286	COG0444	Belongs to the ABC transporter superfamily
AK38_3287	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AK38_3288	COG0601	transmembrane transport
AK38_3291	COG2731	YhcH YjgK YiaL family protein
AK38_3293	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AK38_3295	COG0525	valine-tRNA ligase activity
AK38_3296	COG2927	DNA polymerase III (CHI subunit)
AK38_3298	COG0795	lipopolysaccharide-transporting ATPase activity
AK38_3299	COG0795	lipopolysaccharide-transporting ATPase activity
AK38_330	COG0038	chloride channel
AK38_3301	COG0582	viral genome integration into host DNA
AK38_331	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AK38_3311	COG1459	type II secretion system
AK38_3312	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AK38_3313	COG4969	Belongs to the N-Me-Phe pilin family
AK38_3315	COG3023	N-Acetylmuramoyl-L-alanine amidase
AK38_3316	COG3725	Membrane protein required for beta-lactamase induction
AK38_3317	COG1113	amino acid transport
AK38_3318	COG2186	Transcriptional regulator
AK38_3319	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AK38_3320	COG0508	dehydrogenase complex catalyzes the overall conversion of
AK38_3321	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AK38_3323	COG1049	propionate catabolic process, 2-methylcitrate cycle
AK38_3325	COG0697	spore germination
AK38_3329	COG2132	Multicopper oxidase
AK38_333	COG1940	carbohydrate kinase activity
AK38_3330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AK38_3331	COG0288	reversible hydration of carbon dioxide
AK38_3332	COG1131	(ABC) transporter
AK38_3333	COG0842	Transport permease protein
AK38_3334	COG0726	polysaccharide deacetylase
AK38_3338	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AK38_3339	COG0617	tRNA 3'-terminal CCA addition
AK38_334	COG0583	DNA-binding transcription factor activity
AK38_3340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AK38_3343	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AK38_3344	COG1643	Atp-dependent helicase
AK38_3345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AK38_3346	COG1120	ATPase activity
AK38_3347	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AK38_3348	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AK38_335	COG2814	Major facilitator Superfamily
AK38_3352	COG2860	membrane
AK38_3356	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AK38_3357	COG4999	Histidine kinase
AK38_3357	COG3850	Histidine kinase
AK38_3357	COG3437	response regulator, receiver
AK38_3357	COG2205	protein histidine kinase activity
AK38_3358	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AK38_3359	COG3956	TIGRFAM MazG family protein
AK38_3363	COG0602	queuosine metabolic process
AK38_3364	COG0720	synthase
AK38_337	COG0114	fumarate hydratase activity
AK38_3375	COG0529	Catalyzes the synthesis of activated sulfate
AK38_3383	COG4942	peptidase
AK38_3383	COG1388	LysM domain
AK38_3384	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AK38_3386	COG0698	ribose 5-phosphate isomerase
AK38_3387	COG1063	alcohol dehydrogenase
AK38_3388	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_3389	COG2376	Dihydroxyacetone kinase
AK38_339	COG5339	Protein conserved in bacteria
AK38_3392	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AK38_3396	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AK38_3397	COG1858	cytochrome C peroxidase
AK38_3399	COG4771	TonB-dependent receptor
AK38_34	COG2373	Large extracellular alpha-helical protein
AK38_3402	COG0024	Methionine aminopeptidase
AK38_3404	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AK38_3404	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AK38_3405	COG1070	Carbohydrate kinase
AK38_3406	COG3623	hexulose-6-phosphate isomerase
AK38_3407	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_3408	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_3409	COG1129	ABC transporter
AK38_341	COG0385	Bile acid
AK38_3412	COG1349	DNA-binding transcription factor activity
AK38_3413	COG0235	Class ii aldolase
AK38_3414	COG0243	molybdopterin cofactor binding
AK38_3415	COG0437	4 iron, 4 sulfur cluster binding
AK38_3416	COG3302	dmso reductase anchor subunit
AK38_3417	COG3381	protein complex oligomerization
AK38_3418	COG3038	cytochrome b561
AK38_3419	COG3783	Cytochrome b(562)
AK38_342	COG0673	inositol 2-dehydrogenase activity
AK38_3423	COG1129	ABC transporter
AK38_3424	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_3425	COG3959	Transketolase, thiamine diphosphate binding domain
AK38_3426	COG3958	Transketolase
AK38_3427	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AK38_3435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AK38_3439	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AK38_344	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_3440	COG1238	metal cluster binding
AK38_3441	COG2918	glutathione biosynthetic process
AK38_3445	COG4536	flavin adenine dinucleotide binding
AK38_3446	COG4137	Cytochrome C assembly protein
AK38_3447	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AK38_345	COG1129	ABC transporter
AK38_3453	COG3137	Salt-induced outer membrane protein
AK38_3454	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AK38_3455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AK38_3456	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AK38_3457	COG3279	Response regulator of the LytR AlgR family
AK38_3458	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AK38_3459	COG0287	Prephenate dehydrogenase
AK38_3459	COG1605	Chorismate mutase
AK38_346	COG1879	ABC-type sugar transport system periplasmic component
AK38_3460	COG1605	Chorismate mutase
AK38_3460	COG0077	Prephenate dehydratase
AK38_3463	COG0077	Prephenate dehydratase
AK38_3463	COG1605	Chorismate mutase
AK38_3464	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AK38_3465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AK38_3466	COG0564	pseudouridine synthase activity
AK38_3468	COG0542	response to heat
AK38_3475	COG5544	Lipoprotein
AK38_3476	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AK38_3477	COG0045	succinate-CoA ligase (ADP-forming) activity
AK38_3477	COG1042	CoA-binding domain protein
AK38_3477	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AK38_3479	COG3118	belongs to the thioredoxin family
AK38_3480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AK38_3481	COG2814	Major facilitator Superfamily
AK38_3482	COG1566	PFAM secretion protein HlyD family protein
AK38_3483	COG1846	Transcriptional regulator
AK38_3485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AK38_3486	COG2814	Major facilitator Superfamily
AK38_3495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AK38_3498	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AK38_35	COG4953	penicillin-binding protein 1C
AK38_350	COG2274	protein secretion by the type I secretion system
AK38_3502	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
AK38_3504	COG1960	acyl-CoA dehydrogenase activity
AK38_3506	COG3034	peptidoglycan biosynthetic process
AK38_3507	COG0121	glutamine amidotransferase
AK38_3509	COG1805	sodium ion transport
AK38_351	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AK38_3510	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AK38_3514	COG1477	protein flavinylation
AK38_3518	COG2195	Cleaves the N-terminal amino acid of tripeptides
AK38_3529	COG2226	methyltransferase
AK38_3534	COG1940	carbohydrate kinase activity
AK38_3538	COG0419	ATPase involved in DNA repair
AK38_3539	COG0420	3'-5' exonuclease activity
AK38_3540	COG0745	RESPONSE REGULATOR receiver
AK38_3541	COG5002	protein histidine kinase activity
AK38_3545	COG0366	Alpha amylase catalytic
AK38_3550	COG0450	alkyl hydroperoxide reductase
AK38_3554	COG1862	Preprotein translocase
AK38_3555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AK38_3556	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AK38_3561	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AK38_3561	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AK38_3564	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AK38_3565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AK38_3568	COG0142	geranyltranstransferase activity
AK38_3571	COG0693	protein deglycase activity
AK38_3572	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AK38_3574	COG2814	Major facilitator Superfamily
AK38_3576	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AK38_3577	COG1845	cytochrome c oxidase, subunit III
AK38_3578	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AK38_3579	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AK38_358	COG2207	Transcriptional regulator
AK38_358	COG3708	Transcriptional regulator
AK38_3581	COG2223	nitrite transmembrane transporter activity
AK38_3582	COG3056	Lipoprotein
AK38_3583	COG0271	Belongs to the BolA IbaG family
AK38_3588	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AK38_3589	COG0776	regulation of translation
AK38_359	COG4658	electron transport chain
AK38_3590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AK38_3591	COG1555	photosystem II stabilization
AK38_3592	COG0824	Thioesterase
AK38_3594	COG4533	DNA binding
AK38_3597	COG1522	sequence-specific DNA binding
AK38_3598	COG1132	(ABC) transporter
AK38_3599	COG1132	(ABC) transporter
AK38_360	COG4659	FMN binding
AK38_3600	COG0347	Belongs to the P(II) protein family
AK38_3601	COG0004	ammonium transporteR
AK38_3602	COG1946	Acyl-CoA thioesterase
AK38_3603	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AK38_3604	COG3695	enzyme binding
AK38_3608	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AK38_3610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AK38_3611	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AK38_3612	COG1309	transcriptional regulator
AK38_3613	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AK38_3614	COG3264	Mechanosensitive ion channel
AK38_3614	COG1196	nuclear chromosome segregation
AK38_3616	COG2832	Protein of unknown function (DUF454)
AK38_362	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AK38_3620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AK38_3626	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AK38_3626	COG0543	2 iron, 2 sulfur cluster binding
AK38_363	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AK38_3630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AK38_3639	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AK38_364	COG2271	Major facilitator Superfamily
AK38_3640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AK38_3646	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AK38_3647	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AK38_3648	COG4651	solute:proton antiporter activity
AK38_3648	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AK38_3649	COG2223	nitrite transmembrane transporter activity
AK38_3650	COG0737	Belongs to the 5'-nucleotidase family
AK38_3651	COG0737	Belongs to the 5'-nucleotidase family
AK38_3652	COG0737	Belongs to the 5'-nucleotidase family
AK38_3655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AK38_3656	COG3735	TraB family
AK38_3657	COG2217	Heavy metal translocating P-type atpase
AK38_3658	COG0789	Transcriptional regulator
AK38_3659	COG1585	Membrane protein implicated in regulation of membrane protease activity
AK38_366	COG1966	Carbon starvation protein
AK38_3660	COG0330	HflC and HflK could
AK38_3661	COG3118	belongs to the thioredoxin family
AK38_3662	COG0300	oxidoreductase activity
AK38_3663	COG2755	lipolytic protein G-D-S-L family
AK38_3664	COG4181	ATPase activity
AK38_3665	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AK38_3666	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AK38_3667	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AK38_3669	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AK38_367	COG2879	small protein
AK38_3674	COG1393	Belongs to the ArsC family
AK38_3675	COG4783	chaperone-mediated protein folding
AK38_3676	COG0628	permease
AK38_3679	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AK38_368	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AK38_3680	COG2716	regulation of RNA biosynthetic process
AK38_3682	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AK38_3685	COG2321	neutral zinc metallopeptidase
AK38_3689	COG1876	peptidase activity
AK38_3691	COG1393	Belongs to the ArsC family
AK38_3694	COG1175	transmembrane transport
AK38_3695	COG3842	ATPase activity
AK38_3696	COG3119	arylsulfatase activity
AK38_3697	COG0641	radical SAM
AK38_3698	COG1988	membrane-bound metal-dependent
AK38_3700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AK38_3702	COG2197	response regulator
AK38_3703	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AK38_3703	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AK38_3704	COG3062	negative regulation of establishment of protein localization
AK38_3706	COG3043	anaerobic respiration
AK38_3707	COG3005	denitrification pathway
AK38_3716	COG3111	PFAM Bacterial OB fold (BOF) protein
AK38_3718	COG2837	iron assimilation
AK38_3719	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AK38_372	COG0023	Translation Initiation Factor
AK38_3721	COG4886	Leucine-rich repeat (LRR) protein
AK38_3723	COG2731	YhcH YjgK YiaL family protein
AK38_3724	COG1737	Transcriptional regulator
AK38_3726	COG4150	thiosulfate binding
AK38_3727	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AK38_3728	COG4208	sulfate ABC transporter
AK38_3729	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AK38_3732	COG0745	RESPONSE REGULATOR receiver
AK38_3733	COG5002	protein histidine kinase activity
AK38_3733	COG3850	Histidine kinase
AK38_3735	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AK38_3739	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AK38_3742	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AK38_3743	COG0745	RESPONSE REGULATOR receiver
AK38_3744	COG2205	protein histidine kinase activity
AK38_3749	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AK38_375	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AK38_3751	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AK38_3754	COG3530	Putative quorum-sensing-regulated virulence factor
AK38_376	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AK38_3766	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AK38_3769	COG0667	Aldo Keto reductase
AK38_377	COG0671	phosphoesterase, PA-phosphatase related
AK38_3774	COG0436	Aminotransferase
AK38_3775	COG3038	cytochrome b561
AK38_3781	COG3381	protein complex oligomerization
AK38_3782	COG3302	dmso reductase anchor subunit
AK38_3783	COG0437	4 iron, 4 sulfur cluster binding
AK38_3784	COG0243	molybdopterin cofactor binding
AK38_379	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AK38_3791	COG2951	lytic endotransglycosylase activity
AK38_3803	COG3121	Chaperone
AK38_3804	COG3188	usher protein
AK38_3805	COG3328	transposase activity
AK38_3806	COG3188	usher protein
AK38_381	COG0583	DNA-binding transcription factor activity
AK38_3816	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AK38_3819	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AK38_3820	COG1737	Transcriptional regulator
AK38_3822	COG0560	Phosphoserine phosphatase
AK38_3830	COG2205	protein histidine kinase activity
AK38_3831	COG3170	Tfp pilus assembly protein FimV
AK38_3832	COG2204	response regulator
AK38_3833	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AK38_3833	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AK38_3834	COG0347	Belongs to the P(II) protein family
AK38_3837	COG1017	nitric oxide dioxygenase activity
AK38_3837	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AK38_3840	COG3711	transcriptional antiterminator
AK38_3841	COG2814	Major facilitator Superfamily
AK38_3842	COG3683	transport system, periplasmic component
AK38_3843	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AK38_3845	COG0483	inositol monophosphate 1-phosphatase activity
AK38_3848	COG1104	cysteine desulfurase activity
AK38_3849	COG0822	iron-sulfur transferase activity
AK38_385	COG0616	signal peptide processing
AK38_3852	COG0443	Heat shock 70 kDa protein
AK38_3853	COG0633	Ferredoxin
AK38_3854	COG2975	iron-sulfur cluster assembly
AK38_3858	COG3468	outer membrane autotransporter barrel domain protein
AK38_3859	COG3468	outer membrane autotransporter barrel domain protein
AK38_386	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_3867	COG2976	Protein conserved in bacteria
AK38_3868	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AK38_3871	COG1645	bacterial-type flagellum-dependent swarming motility
AK38_3873	COG0517	IMP dehydrogenase activity
AK38_3873	COG0516	GMP reductase activity
AK38_388	COG1187	pseudouridine synthase activity
AK38_3882	COG3328	transposase activity
AK38_3885	COG0351	phosphomethylpyrimidine kinase
AK38_389	COG0009	L-threonylcarbamoyladenylate synthase
AK38_3891	COG3422	double-strand break repair
AK38_3892	COG0745	RESPONSE REGULATOR receiver
AK38_3893	COG2205	protein histidine kinase activity
AK38_3898	COG3842	ATPase activity
AK38_3900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AK38_3902	COG1176	ABC-type spermidine putrescine transport system, permease component I
AK38_3903	COG1177	transmembrane transport
AK38_3904	COG0443	Heat shock 70 kDa protein
AK38_3905	COG2239	Acts as a magnesium transporter
AK38_3907	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AK38_3909	COG0581	inorganic phosphate transmembrane transporter activity
AK38_3913	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AK38_3914	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AK38_3918	COG2501	S4 domain
AK38_392	COG0512	Glutamine amidotransferase of anthranilate synthase
AK38_3926	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AK38_3927	COG4589	Belongs to the CDS family
AK38_3929	COG2267	carboxylic ester hydrolase activity
AK38_3930	COG2453	phosphatase
AK38_3930	COG0671	phosphoesterase, PA-phosphatase related
AK38_3936	COG0667	Aldo Keto reductase
AK38_3937	COG0656	L-ascorbic acid biosynthetic process
AK38_3939	COG1472	Belongs to the glycosyl hydrolase 3 family
AK38_394	COG0134	indole-3-glycerol-phosphate synthase activity
AK38_394	COG0135	phosphoribosylanthranilate isomerase activity
AK38_3942	COG3328	transposase activity
AK38_3943	COG2850	peptidyl-arginine hydroxylation
AK38_3952	COG3423	Transcriptional regulator
AK38_3953	COG4953	penicillin-binding protein 1C
AK38_3954	COG3328	transposase activity
AK38_3956	COG3037	sugar-specific permease SgaT UlaA
AK38_3957	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AK38_3958	COG0622	Phosphoesterase
AK38_3960	COG1090	epimerase
AK38_3961	COG4598	ABC transporter
AK38_3962	COG4160	amino acid transport
AK38_3963	COG4215	(ABC) transporter
AK38_3964	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AK38_3966	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AK38_3967	COG1286	toxin biosynthetic process
AK38_3968	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AK38_3969	COG0285	dihydrofolate synthase activity
AK38_3971	COG0586	Pfam SNARE associated Golgi protein
AK38_3973	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AK38_3977	COG0697	spore germination
AK38_398	COG3047	cAMP biosynthetic process
AK38_3980	COG1794	racemase activity, acting on amino acids and derivatives
AK38_3981	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AK38_3984	COG3101	peptidyl-lysine hydroxylation
AK38_3985	COG0730	response to heat
AK38_3986	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AK38_3988	COG2890	protein-(glutamine-N5) methyltransferase activity
AK38_3990	COG2062	phosphohistidine phosphatase, SixA
AK38_3993	COG3691	Protein conserved in bacteria
AK38_3996	COG4235	cytochrome complex assembly
AK38_3996	COG3088	subunit of a heme lyase
AK38_3997	COG3088	subunit of a heme lyase
AK38_3997	COG4235	cytochrome complex assembly
AK38_3998	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AK38_3999	COG1138	Cytochrome C-type biogenesis protein
AK38_4	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AK38_40	COG1609	Transcriptional regulator
AK38_4001	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AK38_4002	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AK38_4003	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AK38_4007	COG1704	LemA family
AK38_4009	COG2824	Alkylphosphonate utilization operon protein PhnA
AK38_4015	COG3501	Rhs element vgr protein
AK38_4026	COG3086	response to oxidative stress
AK38_4027	COG3026	antisigma factor binding
AK38_4030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AK38_4032	COG0513	Belongs to the DEAD box helicase family
AK38_404	COG3328	transposase activity
AK38_4043	COG1984	allophanate hydrolase subunit 2
AK38_4044	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AK38_4046	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AK38_4047	COG5212	phosphodiesterase
AK38_4049	COG3272	Protein of unknown function (DUF1722)
AK38_405	COG3328	transposase activity
AK38_4054	COG2205	protein histidine kinase activity
AK38_4055	COG0745	RESPONSE REGULATOR receiver
AK38_4059	COG0033	Phosphoglucomutase
AK38_406	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AK38_4060	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AK38_4064	COG2169	Transcriptional regulator
AK38_4064	COG1917	Cupin 2, conserved barrel domain protein
AK38_4065	COG1447	Phosphotransferase system cellobiose-specific component IIA
AK38_4066	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AK38_4067	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AK38_4068	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AK38_407	COG2350	Protein conserved in bacteria
AK38_4070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AK38_4072	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AK38_4073	COG4413	Urea transporter
AK38_4075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AK38_4080	COG0831	urea catabolic process
AK38_4082	COG1124	(ABC) transporter
AK38_4083	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AK38_4084	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AK38_4086	COG0747	negative chemotaxis
AK38_4087	COG1278	Cold shock
AK38_4089	COG3328	transposase activity
AK38_4097	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AK38_4098	COG4175	Glycine betaine
AK38_4099	COG4176	ABC-type proline glycine betaine transport system permease component
AK38_41	COG0857	belongs to the CobB CobQ family
AK38_41	COG0280	phosphate acetyltransferase
AK38_4100	COG2113	Glycine betaine
AK38_4107	COG0582	viral genome integration into host DNA
AK38_4108	COG2963	transposase activity
AK38_4110	COG0596	Alpha beta hydrolase
AK38_4114	COG0735	belongs to the Fur family
AK38_4120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AK38_4120	COG1263	PTS System
AK38_4120	COG2190	(PTS) system
AK38_4122	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AK38_4123	COG1846	Transcriptional regulator
AK38_4123	COG1940	carbohydrate kinase activity
AK38_4124	COG0647	UMP catabolic process
AK38_4125	COG0367	asparagine synthase
AK38_4131	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AK38_4132	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AK38_4133	COG1702	phosphate starvation-inducible protein PhoH
AK38_4135	COG4535	Mg2 and Co2 transporter CorC
AK38_4136	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AK38_4138	COG0765	amino acid transport
AK38_4139	COG0765	amino acid transport
AK38_414	COG4608	Belongs to the ABC transporter superfamily
AK38_4140	COG1126	abc transporter atp-binding protein
AK38_4141	COG2888	peptidyl-tyrosine sulfation
AK38_4144	COG1466	dna polymerase III delta subunit
AK38_4146	COG0799	negative regulation of ribosome biogenesis
AK38_415	COG0444	Belongs to the ABC transporter superfamily
AK38_4156	COG3328	transposase activity
AK38_4159	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AK38_416	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AK38_417	COG0601	transmembrane transport
AK38_4175	COG1475	DNA binding
AK38_4184	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AK38_4186	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AK38_419	COG2095	MarC family integral membrane protein
AK38_4197	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AK38_420	COG1454	alcohol dehydrogenase
AK38_420	COG1012	belongs to the aldehyde dehydrogenase family
AK38_4212	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AK38_4213	COG1475	DNA binding
AK38_4214	COG1475	DNA binding
AK38_4232	COG3941	tape measure
AK38_4239	COG5301	cellulose 1,4-beta-cellobiosidase activity
AK38_4239	COG5301	cellulose 1,4-beta-cellobiosidase activity
AK38_4241	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AK38_4249	COG3609	addiction module antidote protein, CC2985 family
AK38_4253	COG2801	Transposase and inactivated derivatives
AK38_4260	COG2801	Transposase and inactivated derivatives
AK38_427	COG0745	RESPONSE REGULATOR receiver
AK38_4284	COG0515	serine threonine protein kinase
AK38_4286	COG2801	Transposase and inactivated derivatives
AK38_4289	COG2801	Transposase and inactivated derivatives
AK38_429	COG3328	transposase activity
AK38_4290	COG2963	transposase activity
AK38_4291	COG5599	Phosphatase
AK38_4292	COG1317	bacterial-type flagellum organization
AK38_4294	COG4669	(LipO)protein
AK38_430	COG0788	formyltetrahydrofolate deformylase activity
AK38_4301	COG1450	Type ii and iii secretion system protein
AK38_4303	COG2207	Transcriptional regulator
AK38_4305	COG4792	protein secretion
AK38_4306	COG4791	protein targeting
AK38_4307	COG4794	Type iii secretion
AK38_4308	COG4790	Type iii secretion
AK38_4318	COG4789	Type iii secretion
AK38_4322	COG0457	Tetratricopeptide repeat
AK38_4326	COG4886	Leucine-rich repeat (LRR) protein
AK38_433	COG0583	DNA-binding transcription factor activity
AK38_4330	COG3177	Filamentation induced by cAMP protein fic
AK38_4334	COG2801	Transposase and inactivated derivatives
AK38_434	COG0708	Exodeoxyribonuclease III
AK38_435	COG0494	nUDIX hydrolase
AK38_437	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AK38_438	COG0709	Synthesizes selenophosphate from selenide and ATP
AK38_439	COG0778	Nitroreductase
AK38_440	COG0616	signal peptide processing
AK38_441	COG0252	asparaginase activity
AK38_442	COG1335	isochorismatase
AK38_443	COG3139	Protein of unknown function (DUF1315)
AK38_447	COG3713	MltA-interacting MipA family protein
AK38_448	COG2766	serine protein kinase
AK38_45	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AK38_451	COG0583	DNA-binding transcription factor activity
AK38_453	COG2814	Major facilitator Superfamily
AK38_455	COG2719	SpoVR family
AK38_46	COG0471	metal ion transport
AK38_46	COG0490	domain, Protein
AK38_461	COG1104	cysteine desulfurase activity
AK38_463	COG3328	transposase activity
AK38_48	COG0436	Aminotransferase
AK38_49	COG0583	DNA-binding transcription factor activity
AK38_496	COG3328	transposase activity
AK38_5	COG1686	Belongs to the peptidase S11 family
AK38_51	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AK38_520	COG0582	viral genome integration into host DNA
AK38_522	COG0179	Fumarylacetoacetate (FAA) hydrolase
AK38_523	COG2951	lytic endotransglycosylase activity
AK38_526	COG2894	cell division
AK38_527	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AK38_528	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AK38_529	COG0318	PFAM AMP-dependent synthetase and ligase
AK38_530	COG3065	identical protein binding
AK38_532	COG1199	ATP-dependent helicase activity
AK38_533	COG0251	oxidation-reduction process
AK38_536	COG0800	Aldolase
AK38_538	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AK38_539	COG1737	Transcriptional regulator
AK38_540	COG0469	pyruvate kinase activity
AK38_541	COG1560	Kdo2-lipid A biosynthetic process
AK38_542	COG0739	heme binding
AK38_543	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AK38_545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AK38_55	COG1034	ATP synthesis coupled electron transport
AK38_550	COG0494	nUDIX hydrolase
AK38_552	COG1801	Protein of unknown function DUF72
AK38_553	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AK38_557	COG3102	Protein conserved in bacteria
AK38_561	COG0728	peptidoglycan biosynthetic process
AK38_562	COG0673	inositol 2-dehydrogenase activity
AK38_563	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AK38_566	COG3381	protein complex oligomerization
AK38_569	COG1940	carbohydrate kinase activity
AK38_570	COG0584	glycerophosphoryl diester phosphodiesterase
AK38_571	COG3842	ATPase activity
AK38_574	COG1176	ABC-type spermidine putrescine transport system, permease component I
AK38_575	COG3833	ABC-type maltose transport systems, permease component
AK38_579	COG0659	secondary active sulfate transmembrane transporter activity
AK38_58	COG0839	Belongs to the complex I subunit 6 family
AK38_582	COG0659	secondary active sulfate transmembrane transporter activity
AK38_587	COG2890	protein-(glutamine-N5) methyltransferase activity
AK38_592	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AK38_595	COG0012	GTP binding
AK38_60	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AK38_606	COG5002	protein histidine kinase activity
AK38_61	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AK38_615	COG0500	methyltransferase
AK38_620	COG3328	transposase activity
AK38_629	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AK38_630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AK38_631	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AK38_634	COG0402	S-adenosylhomocysteine deaminase activity
AK38_64	COG2731	YhcH YjgK YiaL family protein
AK38_644	COG3842	ATPase activity
AK38_645	COG0395	ABC-type sugar transport system, permease component
AK38_646	COG1175	transmembrane transport
AK38_648	COG0673	inositol 2-dehydrogenase activity
AK38_649	COG2188	Transcriptional regulator
AK38_65	COG3265	gluconokinase activity
AK38_655	COG3328	transposase activity
AK38_656	COG3328	transposase activity
AK38_66	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_679	COG2197	response regulator
AK38_68	COG1609	Transcriptional regulator
AK38_681	COG3136	membrane protein required for alginate biosynthesis
AK38_685	COG1113	amino acid transport
AK38_689	COG2822	iron ion transport
AK38_69	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AK38_690	COG0672	)-iron permease
AK38_693	COG0506	proline dehydrogenase activity
AK38_693	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AK38_693	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AK38_701	COG1191	sigma factor activity
AK38_707	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AK38_708	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AK38_709	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AK38_712	COG1677	Flagellar hook-basal body complex protein FliE
AK38_716	COG1157	protein secretion by the type III secretion system
AK38_719	COG1580	Controls the rotational direction of flagella during chemotaxis
AK38_72	COG0129	dihydroxy-acid dehydratase activity
AK38_724	COG1987	bacterial-type flagellum assembly
AK38_728	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AK38_729	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_730	COG1129	ABC transporter
AK38_732	COG1172	Belongs to the binding-protein-dependent transport system permease family
AK38_733	COG3347	Dehydrogenase
AK38_733	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_734	COG2390	Transcriptional regulator
AK38_736	COG1256	bacterial-type flagellum assembly
AK38_74	COG4575	ribosome binding
AK38_744	COG1558	bacterial-type flagellum-dependent cell motility
AK38_745	COG1815	bacterial-type flagellum-dependent cell motility
AK38_747	COG2747	anti-sigma28 factor FlgM
AK38_748	COG3418	PFAM FlgN family protein
AK38_753	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AK38_754	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AK38_759	COG2372	response to copper ion
AK38_76	COG1169	isochorismate synthase
AK38_760	COG1528	Iron-storage protein
AK38_763	COG1770	oligopeptidase
AK38_766	COG3141	response to X-ray
AK38_767	COG0513	Belongs to the DEAD box helicase family
AK38_772	COG1760	l-serine dehydratase
AK38_773	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AK38_774	COG2368	4-hydroxyphenylacetate
AK38_777	COG3971	2-oxopent-4-enoate hydratase activity
AK38_779	COG3384	dioxygenase
AK38_780	COG1012	belongs to the aldehyde dehydrogenase family
AK38_783	COG1846	Transcriptional regulator
AK38_784	COG1253	flavin adenine dinucleotide binding
AK38_785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AK38_785	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AK38_786	COG3715	PTS system
AK38_787	COG3716	PTS system mannose fructose sorbose family IID component
AK38_79	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AK38_791	COG5001	Diguanylate cyclase
AK38_791	COG5002	protein histidine kinase activity
AK38_791	COG3447	MASE1 domain protein
AK38_796	COG2226	methyltransferase
AK38_801	COG1113	amino acid transport
AK38_808	COG2207	Transcriptional regulator
AK38_810	COG1132	(ABC) transporter
AK38_82	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AK38_821	COG3328	transposase activity
AK38_822	COG1917	Cupin 2, conserved barrel domain protein
AK38_824	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_826	COG1175	transmembrane transport
AK38_827	COG0395	ABC-type sugar transport system, permease component
AK38_828	COG3842	ATPase activity
AK38_829	COG1653	transport
AK38_830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AK38_831	COG1988	membrane-bound metal-dependent
AK38_833	COG3023	N-Acetylmuramoyl-L-alanine amidase
AK38_835	COG0823	Involved in the tonB-independent uptake of proteins
AK38_836	COG2814	Major facilitator Superfamily
AK38_837	COG3121	Chaperone
AK38_840	COG3121	Chaperone
AK38_841	COG3539	Fimbrial protein
AK38_844	COG0793	Belongs to the peptidase S41A family
AK38_846	COG1956	GAF domain-containing protein
AK38_847	COG2995	paraquat-inducible protein a
AK38_848	COG3008	intermembrane lipid transfer
AK38_852	COG3121	Chaperone
AK38_865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AK38_868	COG5295	Hep Hag repeat protein
AK38_870	COG3023	N-Acetylmuramoyl-L-alanine amidase
AK38_871	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AK38_872	COG0745	RESPONSE REGULATOR receiver
AK38_874	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AK38_877	COG0840	transmembrane signaling receptor activity
AK38_88	COG1126	abc transporter atp-binding protein
AK38_881	COG2964	Protein conserved in bacteria
AK38_883	COG0251	oxidation-reduction process
AK38_884	COG2271	Major facilitator Superfamily
AK38_885	COG0835	chemotaxis
AK38_886	COG0643	Histidine kinase
AK38_886	COG2198	Histidine kinase
AK38_887	COG1360	Flagellar Motor Protein
AK38_89	COG0765	amino acid transport
AK38_892	COG1285	pathogenesis
AK38_893	COG0840	transmembrane signaling receptor activity
AK38_894	COG0840	transmembrane signaling receptor activity
AK38_898	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_898	COG3321	synthase
AK38_898	COG0604	alcohol dehydrogenase
AK38_9	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AK38_90	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AK38_900	COG1522	sequence-specific DNA binding
AK38_905	COG1733	regulation of RNA biosynthetic process
AK38_906	COG0702	epimerase
AK38_907	COG0840	transmembrane signaling receptor activity
AK38_910	COG0538	isocitrate dehydrogenase activity
AK38_911	COG1187	pseudouridine synthase activity
AK38_915	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AK38_917	COG0745	RESPONSE REGULATOR receiver
AK38_919	COG2850	peptidyl-arginine hydroxylation
AK38_922	COG1940	carbohydrate kinase activity
AK38_923	COG4591	ABC-type transport system involved in lipoprotein release permease component
AK38_925	COG4591	ABC-type transport system involved in lipoprotein release permease component
AK38_926	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AK38_927	COG3134	Outer membrane lipoprotein
AK38_930	COG3328	transposase activity
AK38_933	COG1252	NADH dehydrogenase
AK38_935	COG1472	Belongs to the glycosyl hydrolase 3 family
AK38_938	COG5633	Lipoprotein
AK38_939	COG0537	adenosine 5'-monophosphoramidase activity
AK38_940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AK38_942	COG1263	PTS System
AK38_942	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AK38_943	COG0084	hydrolase, TatD family'
AK38_944	COG0470	DNA polymerase III
AK38_946	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AK38_947	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AK38_949	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AK38_955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AK38_956	COG1399	metal-binding, possibly nucleic acid-binding protein
AK38_957	COG0424	maF-like protein
AK38_959	COG0564	pseudouridine synthase activity
AK38_96	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AK38_960	COG1530	ribonuclease E activity
AK38_961	COG3328	transposase activity
AK38_962	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AK38_965	COG3328	transposase activity
AK38_967	COG2223	nitrite transmembrane transporter activity
AK38_972	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AK38_977	COG3122	Protein conserved in bacteria
AK38_981	COG0534	Mate efflux family protein
AK38_985	COG4948	Mandelate Racemase Muconate Lactonizing
AK38_987	COG1028	Short-chain dehydrogenase reductase Sdr
AK38_988	COG3011	Protein conserved in bacteria
AK38_989	COG2271	Major facilitator Superfamily
AK38_990	COG3328	transposase activity
AK38_991	COG1470	cell adhesion involved in biofilm formation
AK38_991	COG1388	LysM domain
AK38_994	COG2925	Exonuclease
AK38_995	COG0531	amino acid
AK38_997	COG0371	Dehydrogenase
AK38_998	COG1129	ABC transporter
AK38_999	COG1129	ABC transporter