locus-tag class description BAY22_00030 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BAY22_00035 ENOG4108MG3 formate dehydrogenase BAY22_00050 ENOG4105EM7 Selenocysteine-specific translation elongation factor BAY22_00055 ENOG4105D13 transposase BAY22_00085 ENOG4105DQ6 Transposase BAY22_00100 ENOG4105C7B Threonine dehydratase BAY22_00105 ENOG4105D99 atp gtp-binding protein BAY22_00110 ENOG4105D99 atp gtp-binding protein BAY22_00115 ENOG4105R2A (LipO)protein BAY22_00135 ENOG4105JKW Valine--pyruvate aminotransferase BAY22_00145 ENOG4107T9C Alpha amylase catalytic region BAY22_00160 ENOG4108ZG0 Ompa motb domain protein BAY22_00170 ENOG4108R3E Dna-3-methyladenine glycosylase i BAY22_00185 ENOG4106JH6 (LipO)protein BAY22_00190 ENOG4105CTS PTS system mannitol-specific BAY22_00200 ENOG4105E61 Mannitol repressor protein BAY22_00205 ENOG4108YYI Protein of unknown function (DUF2810) BAY22_00220 ENOG4105C8Q Methyl-accepting chemotaxis BAY22_00225 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAY22_00235 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BAY22_00240 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BAY22_00245 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BAY22_00250 ENOG4108MG3 formate dehydrogenase BAY22_00265 ENOG4105EM7 Selenocysteine-specific translation elongation factor BAY22_00270 ENOG4105EM7 Selenocysteine-specific translation elongation factor BAY22_00275 ENOG4105D13 transposase BAY22_00305 ENOG4105DQ6 Transposase BAY22_00320 ENOG4105MEV Acyl-transferase BAY22_00325 ENOG4106EAR Fimbrial protein BAY22_00340 ENOG4108TTM chaperone BAY22_00350 ENOG4105CMG Carbohydrate kinase BAY22_00360 ENOG4105DFW ABC transporter BAY22_00370 ENOG4107RNG ABC transporter BAY22_00375 ENOG4105T16 Transcriptional regulator (AraC family) BAY22_00380 ENOG4105DFP Integrase BAY22_00390 ENOG4105ZTC transcriptional activator, Ogr delta BAY22_00420 ENOG4108IPW abc transporter atp-binding protein BAY22_00425 ENOG4105CM4 permease protein BAY22_00455 ENOG4105C6T cysteine synthase BAY22_00465 ENOG4105C84 Histidine ammonia-lyase BAY22_00470 ENOG4105C85 amino acid BAY22_00480 ENOG4105DIJ Phosphoethanolamine transferase BAY22_00485 ENOG4108KX4 response regulator BAY22_00490 ENOG4105BZU Histidine kinase BAY22_00505 ENOG4105BZU Histidine kinase BAY22_00510 ENOG4105CXY transporter BAY22_00525 ENOG4105D5K Hemolysin activator protein BAY22_00535 ENOG4105DEF Extracellular solute-binding protein, family 5 BAY22_00545 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAY22_00550 ENOG4105C3U ABC transporter BAY22_00555 ENOG4108JQ7 (ABC) transporter BAY22_00560 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BAY22_00565 ENOG4105BZU Histidine kinase BAY22_00570 ENOG4108PU9 oligogalacturonate-specific porin BAY22_00590 ENOG4105CS0 peptidase BAY22_00595 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BAY22_00600 ENOG4105VSH 4-oxalocrotonate tautomerase BAY22_00605 ENOG4105CMB EAL domain-containing protein BAY22_00610 ENOG41066T0 asmA family BAY22_00615 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) BAY22_00620 ENOG4107H3J ribonuclease BAY22_00645 ENOG4105BZW Glycerate kinase BAY22_00650 ENOG4107QQ0 gntp family BAY22_00655 ENOG4107VHA regulatoR BAY22_00660 ENOG4105DC8 reductase BAY22_00665 ENOG4105D6S protein involved in catabolism of external DNA BAY22_00670 ENOG4105DGW oligopeptidase A BAY22_00690 ENOG4108M6U Universal stress protein A BAY22_00700 ENOG4108RS6 transposase BAY22_00705 ENOG4105CJ3 phosphate transporter BAY22_00725 ENOG4105CNN ABC, transporter BAY22_00730 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAY22_00740 ENOG4105D2N Aldolase BAY22_00750 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAY22_00760 ENOG4105C2I pirin domain protein BAY22_00765 ENOG4105DIQ Transcriptional regulator BAY22_00770 ENOG4105C6Z Gluconate BAY22_00775 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BAY22_00795 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BAY22_00800 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAY22_00830 ENOG4108HRK Histidine kinase BAY22_00855 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BAY22_00860 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAY22_00880 ENOG4105DQ6 Transposase BAY22_00910 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BAY22_00930 ENOG4105X58 receptor BAY22_00945 ENOG4107QZV Type I secretion membrane fusion protein BAY22_00950 ENOG4105YHG TonB family BAY22_00955 ENOG4107QN2 dihydrolipoyl dehydrogenase BAY22_00960 ENOG4105EHV domain protein BAY22_00965 ENOG4105C5Q Transcriptional regulator BAY22_00980 ENOG4108Y73 Membrane BAY22_01035 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BAY22_01040 ENOG4105C2J ABC transporter BAY22_01045 ENOG4107R9N ABC transporter BAY22_01050 ENOG41062B0 ABC transporter, permease BAY22_01060 ENOG4108WFC UPF0438 protein yifE BAY22_01065 ENOG4105C0P Mg chelatase subunit ChlI BAY22_01075 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BAY22_01080 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAY22_01090 ENOG4105C7B Threonine dehydratase BAY22_01125 ENOG4105EMY transcriptional regulator BAY22_01165 ENOG4108VEV chaperone BAY22_01175 ENOG4105CW0 outer membrane usher protein BAY22_01180 ENOG4105GQR Chaperone BAY22_01205 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BAY22_01215 ENOG4105C4R Atp-dependent dna helicase BAY22_01235 ENOG4105K63 Thioredoxin BAY22_01245 ENOG4105ESV Glycosyl transferase, family 4 BAY22_01250 ENOG4105SFE lipopolysaccharide biosynthesis protein BAY22_01255 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAY22_01260 ENOG4108IJ1 Dehydrogenase BAY22_01265 ENOG4105C1B dTDP-glucose 4-6-dehydratase BAY22_01270 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAY22_01275 ENOG4108WJ1 acetyltransferase BAY22_01280 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAY22_01285 ENOG4105EGZ biosynthesis protein BAY22_01305 ENOG4105C85 amino acid BAY22_01320 ENOG4105S8Q sugar efflux transporter BAY22_01335 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAY22_01345 ENOG4108RS6 transposase BAY22_01350 ENOG41064T2 transcriptional regulator, lysR family BAY22_01360 ENOG4108IQE Amp-dependent synthetase and ligase BAY22_01370 ENOG4105C7K acetolactate synthase BAY22_01375 ENOG4108ZP8 Acetolactate synthase small subunit BAY22_01380 ENOG4108RS6 transposase BAY22_01390 ENOG4107B7Y DNA-binding transcriptional regulator FruR BAY22_01395 ENOG4108RNS Exports L-alanine (By similarity) BAY22_01410 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BAY22_01415 ENOG4105CJN penicillin-binding protein BAY22_01420 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAY22_01425 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BAY22_01440 ENOG4105CNI cell division protein FtsW BAY22_01460 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BAY22_01465 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAY22_01470 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAY22_01495 ENOG4105M6F mutator MutT protein BAY22_01510 ENOG4105CHF Glutathione S-transferase BAY22_01515 ENOG4108VBZ doxx family BAY22_01525 ENOG41090KG Inner membrane protein YqjE BAY22_01530 ENOG4105NE1 Conserved Protein BAY22_01550 ENOG4106W5V Membrane BAY22_01565 ENOG4105DPW Major facilitator superfamily MFS_1 BAY22_01580 ENOG4107QZW Altronate oxidoreductase BAY22_01585 ENOG4105CTX dehydratase BAY22_01590 ENOG4105P66 Membrane BAY22_01595 ENOG4108RS6 transposase BAY22_01605 ENOG4105EE0 oxidoreductase BAY22_01610 ENOG4108VKG metal-dependent hydrolase BAY22_01625 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAY22_01630 ENOG4108YK4 Acid-resistance membrane protein BAY22_01650 ENOG4108M24 von Willebrand factor, type A BAY22_01665 ENOG4108M24 von Willebrand factor, type A BAY22_01670 ENOG4105D5K Hemolysin activator protein BAY22_01685 ENOG4105CKT filamentous hemagglutinin BAY22_01690 ENOG4105CKT filamentous hemagglutinin BAY22_01700 ENOG4105CKT filamentous hemagglutinin BAY22_01705 ENOG4105CKT filamentous hemagglutinin BAY22_01730 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 BAY22_01735 ENOG4107KJX Transcriptional regulator BAY22_01740 ENOG4108IJG ABC transporter substrate-binding protein BAY22_01750 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BAY22_01760 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BAY22_01770 ENOG4108MI0 Resistance protein BAY22_01775 ENOG4105J12 Multidrug resistance protein mdtN BAY22_01795 ENOG4105CHM Aminotransferase BAY22_01815 ENOG4105KME endoribonuclease L-psp BAY22_01905 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAY22_01910 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAY22_01915 ENOG4105VCC 30S ribosomal protein S21 BAY22_01930 ENOG4107ZVW dihydroneopterin aldolase BAY22_01945 ENOG4106MWK domain protein BAY22_01950 ENOG4105I7R Adenylate cyclase BAY22_01965 ENOG4105DVH amino acid BAY22_01970 ENOG4105W0Z cytoplasmic protein BAY22_01980 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BAY22_01985 ENOG4106032 Glutathionylspermidine synthase BAY22_02000 ENOG4105DFG type I secretion outer membrane protein BAY22_02005 ENOG41087AY ADP-Ribose pyrophosphatase BAY22_02010 ENOG4108SX3 cytoplasmic protein BAY22_02015 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BAY22_02020 ENOG4105IPS esterase BAY22_02025 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAY22_02030 ENOG4105CR8 Transcriptional regulator BAY22_02035 ENOG4105NF4 modulator of drug activity BAY22_02040 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAY22_02045 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BAY22_02050 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BAY22_02060 ENOG4105CV8 reductase BAY22_02070 ENOG4108I6A alcohol dehydrogenase BAY22_02075 ENOG4105CF7 AraC family transcriptional regulator BAY22_02085 ENOG4105C28 cystathionine BAY22_02090 ENOG4105CWK Biopolymer transport protein, ExbB BAY22_02095 ENOG4108ZZF transport protein (ExbD) BAY22_02165 ENOG4108RS6 transposase BAY22_02170 ENOG4108RS6 transposase BAY22_02175 ENOG4106PG1 outer membrane usher protein BAY22_02180 ENOG4106P2F Pfam:Pili_assembly_C BAY22_02190 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BAY22_02210 ENOG4105D00 flagellar biosynthetic protein flhB BAY22_02215 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BAY22_02220 ENOG4105VS8 Flagellar biosynthetic protein fliq BAY22_02225 ENOG4105CN7 Flagellar biosynthetic protein FliP BAY22_02230 ENOG4105DD5 Flagellar motor switch protein BAY22_02240 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAY22_02250 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BAY22_02265 ENOG4108JIR Flagellum-specific ATP synthase BAY22_02285 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA BAY22_02290 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAY22_02295 ENOG4108ZC9 flagellar basal-body rod protein flgc BAY22_02300 ENOG4105W00 Flagellar hook capping protein BAY22_02305 ENOG4105BZE flagellar hook protein, FlgE BAY22_02315 ENOG4108RS6 transposase BAY22_02320 ENOG4108KPB Flagellar basal-body rod protein FlgF BAY22_02325 ENOG4105CGA flagellar basal-body rod protein FlgG BAY22_02330 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BAY22_02335 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BAY22_02345 ENOG4105E1Q flagellar hook-associated protein BAY22_02365 ENOG4108M3R transcriptional activator CadC BAY22_02385 ENOG410804A Flagellar hook-associated 2 domain-containing protein BAY22_02415 ENOG4107RD7 Flagellar Motor Protein, MotA BAY22_02470 ENOG4105ETE Transcriptional regulator (LacI family BAY22_02475 ENOG4105C8P )-transporter BAY22_02480 ENOG41062WK cellular response to acidity BAY22_02490 ENOG4105CNA YD repeat protein BAY22_02500 ENOG4105CS6 Rhs element vgr protein BAY22_02515 ENOG4107EFN gluconate transport system permease 3 BAY22_02565 ENOG4105C0W non-ribosomal peptide synthetase BAY22_02575 ENOG4105C0W non-ribosomal peptide synthetase BAY22_02610 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BAY22_02635 ENOG4105CPC Aldo Keto reductase BAY22_02665 ENOG41060NJ transcriptional regulator BAY22_02670 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAY22_02675 ENOG4105RQF LysR family Transcriptional regulator BAY22_02680 ENOG4105F27 Major Facilitator BAY22_02685 ENOG4105EJC lysr family transcriptional regulator BAY22_02700 ENOG4105C8Q Methyl-accepting chemotaxis BAY22_02760 ENOG4105D7Q type ii secretion system BAY22_02770 ENOG4107QHF type ii secretion system protein e BAY22_02790 ENOG4107B2H carbonic anhydrase BAY22_02830 ENOG4108RS6 transposase BAY22_02835 ENOG4105CBG Sulfatase BAY22_02840 ENOG4105E98 transcriptional regulator DeoR family BAY22_02845 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BAY22_02850 ENOG4105E70 isomerase BAY22_02855 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BAY22_02860 ENOG4105ETZ PTS System BAY22_02865 ENOG4105F3R pts system mannose fructose sorbose family iid BAY22_02870 ENOG4108YTN IIa component BAY22_02875 ENOG4105CE4 GlcNAc 6-P deacetylase BAY22_02880 ENOG4105CHR reductase BAY22_02890 ENOG4105C4X radical SAM domain protein BAY22_02895 ENOG4105ENH Sulfatase BAY22_02905 ENOG4105D2N Aldolase BAY22_02920 ENOG4105ETE Transcriptional regulator (LacI family BAY22_02925 ENOG4105DPW Major facilitator superfamily MFS_1 BAY22_02935 ENOG4105ETE Transcriptional regulator (LacI family BAY22_02945 ENOG4105CI1 PTS System BAY22_02950 ENOG4105C4C beta-galactosidase BAY22_02960 ENOG4105EG2 ABC transporter, permease BAY22_02970 ENOG4107FKK extracellular solute-binding protein family 1 BAY22_02985 ENOG4105CNN ABC, transporter BAY22_02990 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAY22_03000 ENOG4108UY0 (LipO)protein BAY22_03005 ENOG4105NTW Transcriptional regulator BAY22_03100 ENOG4105WJ3 XRE family Transcriptional regulator BAY22_03105 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation BAY22_03130 ENOG4105DFP Integrase BAY22_03150 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAY22_03155 ENOG4105T95 Thiol disulfide interChange protein BAY22_03160 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAY22_03165 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BAY22_03170 ENOG4105CT7 inner membrane cred family protein BAY22_03175 ENOG4105EB3 Histidine kinase BAY22_03180 ENOG4105E3W Two component transcriptional regulator (Winged helix family BAY22_03190 ENOG4105Y75 tpr repeat protein BAY22_03205 ENOG4108UT2 hemolysin iii BAY22_03245 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BAY22_03250 ENOG4105D0A hydroxylase BAY22_03255 ENOG4107RAQ aminopeptidase BAY22_03275 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAY22_03280 ENOG4108JQ1 Dehydrogenase BAY22_03285 ENOG4105E66 phosphoriboisomerase A BAY22_03295 ENOG4105MPN Membrane BAY22_03305 ENOG4105D64 Mechanosensitive ion channel BAY22_03310 ENOG4105D2N Aldolase BAY22_03335 ENOG4108RS6 transposase BAY22_03340 ENOG4105CV1 Transketolase (EC 2.2.1.1) BAY22_03345 ENOG4108K0D peptidase, M48 BAY22_03355 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BAY22_03365 ENOG4105GPY SprT protein BAY22_03370 ENOG4105RWS endonuclease I BAY22_03375 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAY22_03380 ENOG4105D7Z glutathione synthase BAY22_03395 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) BAY22_03405 ENOG4105CZX twitching motility protein BAY22_03410 ENOG4105DFA alanine racemase domain protein BAY22_03415 ENOG4105II7 pyrroline-5-carboxylate reductase BAY22_03420 ENOG4108VIA integral membrane protein BAY22_03430 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BAY22_03435 ENOG4105CSA Coproporphyrinogen iii oxidase BAY22_03440 ENOG4105EUK rtx toxin RtxA BAY22_03445 ENOG4105K33 Periplasmic Protein BAY22_03450 ENOG4105K33 Periplasmic Protein BAY22_03455 ENOG4105CSV Glutaminase BAY22_03460 ENOG41090ED Protein with unknown function (DUF469) BAY22_03470 ENOG4105CEN a g-specific adenine glycosylase BAY22_03495 ENOG4105CNN ABC, transporter BAY22_03500 ENOG4105C2J ABC transporter BAY22_03505 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAY22_03510 ENOG4105CXN decarboxylase BAY22_03585 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAY22_03595 ENOG4105CDV Ompa motb domain protein BAY22_03690 ENOG4105DUU IucA IucC family protein BAY22_03695 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BAY22_03705 ENOG4105CT4 transporter BAY22_03715 ENOG4105DQ6 Transposase BAY22_03720 ENOG4105BZU Histidine kinase BAY22_03730 ENOG4105C1P efflux transporter, rnd family, mfp subunit BAY22_03770 ENOG4105CFC Transporter BAY22_03775 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAY22_03780 ENOG4107ZSV Receptor BAY22_03815 ENOG4105DSY exodeoxyribonuclease V, gamma BAY22_03820 ENOG4107QXK peptidase BAY22_03825 ENOG4107QKA exodeoxyribonuclease V beta BAY22_03830 ENOG4107QYX exodeoxyribonuclease v alpha BAY22_03840 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAY22_03855 ENOG4105CA3 membrane-bound lytic murein transglycosylase BAY22_03860 ENOG4105CUZ uba thif-type nad fad binding protein BAY22_03865 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BAY22_03870 ENOG4105C9B Cysteine desulfurase BAY22_03875 ENOG4105ETT transcriptional Regulator, LysR family BAY22_03880 ENOG4105M08 Membrane BAY22_03890 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease BAY22_03895 ENOG4105EWT decarboxylase family BAY22_03910 ENOG4108RS6 transposase BAY22_03915 ENOG4105WP7 tRNA pseudouridine synthase C BAY22_03920 ENOG4105DR9 pseudouridine synthase BAY22_03925 ENOG4105QDK Flavodoxin BAY22_03945 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAY22_03975 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BAY22_03980 ENOG4105KNE Phosphatidate cytidylyltransferase BAY22_03985 ENOG4105DZP Membrane-associated zinc metalloprotease BAY22_03995 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BAY22_04015 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BAY22_04025 ENOG4105C0B DNA polymerase III (alpha subunit) BAY22_04035 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAY22_04040 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAY22_04050 ENOG4105M1T rho-binding antiterminator BAY22_04060 ENOG4108VWS Yaeq family BAY22_04065 ENOG4108YZN class I peptide chain release factor BAY22_04070 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BAY22_04080 ENOG4108R96 Methyltransferase, YaeB family BAY22_04085 ENOG4108R8X outer membrane lipoprotein BAY22_04090 ENOG4105D01 (LipO)protein BAY22_04095 ENOG4108UMI ABC transporter, permease BAY22_04105 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BAY22_04135 ENOG4105CV8 reductase BAY22_04150 ENOG4105E9H Lytic Murein transglycosylase BAY22_04170 ENOG4108JDX DNA polymerase iii, epsilon subunit BAY22_04180 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BAY22_04210 ENOG4105VUH addiction module killer protein BAY22_04270 ENOG4105DFP Integrase BAY22_04275 ENOG4108RS6 transposase BAY22_04295 ENOG4108Z1B Cyclase dehydrase BAY22_04305 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BAY22_04310 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAY22_04315 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAY22_04325 ENOG4105BZN citrate synthase BAY22_04330 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BAY22_04335 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BAY22_04345 ENOG4105E33 succinate dehydrogenase BAY22_04355 ENOG4105C7S Dehydrogenase BAY22_04365 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAY22_04370 ENOG4105C4M (Ubiquinol oxidase) subunit I BAY22_04375 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAY22_04385 ENOG4105KJB cyd operon protein YbgE BAY22_04390 ENOG4107YD3 Thioesterase BAY22_04395 ENOG4105E02 MotA TolQ exbB proton channel BAY22_04400 ENOG4105M8F Biopolymer transport protein exbD tolR BAY22_04405 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BAY22_04405 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BAY22_04415 ENOG4105KCK Peptidoglycan-associated lipoprotein BAY22_04420 ENOG4105UFD tol-pal system protein YbgF BAY22_04450 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BAY22_04455 ENOG4105PGM cation diffusion facilitator family transporter BAY22_04460 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BAY22_04475 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BAY22_04490 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BAY22_04505 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BAY22_04510 ENOG4105CMR udp-glucose 4-epimerase BAY22_04525 ENOG4105DKW ABC transporter BAY22_04530 ENOG4105F4R Transcriptional regulator mode BAY22_04535 ENOG410680R Protein of unknown function (DUF2592) BAY22_04540 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAY22_04545 ENOG4105E0C molybdate abc transporter BAY22_04555 ENOG4108K4B hydrolase BAY22_04580 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAY22_04585 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BAY22_04590 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAY22_04595 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAY22_04600 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BAY22_04605 ENOG4105CHW UPF0052 protein BAY22_04615 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAY22_04625 ENOG4105M00 molybdopterin converting factor, subunit 1 BAY22_04630 ENOG4108ZAF Molybdopterin BAY22_04635 ENOG4105HFZ Membrane BAY22_04640 ENOG4108RS6 transposase BAY22_04660 ENOG4105C94 Transporter BAY22_04665 ENOG4105CN8 Transcriptional regulator BAY22_04675 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BAY22_04685 ENOG4108RS6 transposase BAY22_04695 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BAY22_04705 ENOG41061WM D-Alanyl-D-Alanine BAY22_04710 ENOG4105CXG d-lactate dehydrogenase BAY22_04720 ENOG4105N1F Hnh endonuclease BAY22_04730 ENOG4105Y3U Transglycosylase-associated protein BAY22_04740 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein BAY22_04755 ENOG4108W15 Protein of unknown function (DUF1456) BAY22_04765 ENOG4105C32 Amino acid ABC transporter (Permease) BAY22_04770 ENOG4105CNN ABC, transporter BAY22_04775 ENOG4108JJB ABC transporter BAY22_04780 ENOG4108IV0 ABC, transporter BAY22_04795 ENOG4105KHC sulfurtransferase BAY22_04800 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BAY22_04805 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BAY22_04810 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BAY22_04815 ENOG4108IJ8 ABC transporter BAY22_04820 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BAY22_04825 ENOG4105D5Q Arginine ornithine antiporter BAY22_04830 ENOG4105CXN decarboxylase BAY22_04840 ENOG4105FDR Membrane BAY22_04850 ENOG4105DVT helicase BAY22_04855 ENOG4105CH6 catalase BAY22_04860 ENOG4108UII YfaZ family BAY22_04865 ENOG4105E0U tyrosine-specific transport protein BAY22_04880 ENOG4105XPH Ferredoxin BAY22_04885 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAY22_04890 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAY22_04900 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAY22_04910 ENOG4105BZU Histidine kinase BAY22_04915 ENOG41068CG regulatoR BAY22_04920 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BAY22_04925 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BAY22_04930 ENOG4106UW1 Major Facilitator superfamily BAY22_04935 ENOG4105FCK Membrane BAY22_04940 ENOG4108RS6 transposase BAY22_04945 ENOG4108RS6 transposase BAY22_04960 ENOG4107R6D beta-lactam binding protein AmpH BAY22_04970 ENOG4105CT4 transporter BAY22_04980 ENOG4105C8Q Methyl-accepting chemotaxis BAY22_04990 ENOG4105Y50 Virulence Protein BAY22_05000 ENOG4105HRS Antitermination protein BAY22_05005 ENOG4105G63 Type III effector Hrp-dependent BAY22_05015 ENOG4105MVE transcriptional regulator BAY22_05020 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BAY22_05040 ENOG4105TKZ Tail Sheath BAY22_05080 ENOG4108T86 baseplate J family protein BAY22_05100 ENOG4108Q3X Transcriptional regulator BAY22_05105 ENOG4105CS2 ec 3.2.1.21 BAY22_05120 ENOG4105GMB type VI secretion system effector, hcp1 family BAY22_05135 ENOG4105E68 Sulfatase BAY22_05140 ENOG4105PAN UPF0352 protein BAY22_05150 ENOG4108RS6 transposase BAY22_05160 ENOG4105CFI type iii restriction protein res subunit BAY22_05165 ENOG4105I08 Pseudouridine synthase BAY22_05170 ENOG4105C2C drug resistance transporter, Bcr CflA BAY22_05175 ENOG4105HG6 BAY22_05180 ENOG4108JQ5 ABC transporter BAY22_05185 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BAY22_05190 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BAY22_05195 ENOG4105E43 Extracellular solute-binding protein, family 5 BAY22_05200 ENOG4105CXC rtn protein BAY22_05205 ENOG4107TT5 NLP P60 protein BAY22_05210 ENOG41076MN Phosphoesterase, PA-phosphatase related BAY22_05215 ENOG4105CKI cobalamin synthesis protein BAY22_05225 ENOG4107YCY Transcriptional regulator BAY22_05230 ENOG4105DEI Mannitol dehydrogenase BAY22_05235 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BAY22_05250 ENOG4105KRS Proteinase inhibitor BAY22_05255 ENOG4105CHR reductase BAY22_05270 ENOG4105C26 Dehydrogenase BAY22_05280 ENOG4105E66 phosphoriboisomerase A BAY22_05290 ENOG4105C2J ABC transporter BAY22_05295 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BAY22_05305 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BAY22_05310 ENOG4105DE4 1-phosphofructokinase BAY22_05315 ENOG4105DM4 PTS System BAY22_05320 ENOG4108SGD regulatory protein BAY22_05335 ENOG4108UIF Chaperone BAY22_05340 ENOG4108D1K outer membrane usher protein BAY22_05350 ENOG4105HMI Membrane BAY22_05355 ENOG4105DUM transcriptional regulator, lysR family BAY22_05360 ENOG4108IQI permease BAY22_05370 ENOG4105EHG Permease protein BAY22_05380 ENOG4105D05 Receptor BAY22_05385 ENOG4108TGY Glutathione S-transferase BAY22_05400 ENOG4105D01 (LipO)protein BAY22_05410 ENOG4108UMI ABC transporter, permease BAY22_05415 ENOG4105DZ1 carboxypeptidase BAY22_05425 ENOG4105C44 Serine transporter BAY22_05430 ENOG4107FB0 transcriptional regulator DeoR family BAY22_05435 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BAY22_05440 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAY22_05450 ENOG4105D0C transport protein BAY22_05455 ENOG41090BQ Glutaredoxin BAY22_05460 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BAY22_05470 ENOG4108RMJ sensory transduction regulator BAY22_05475 ENOG4107RUE extracellular solute-binding protein family 1 BAY22_05480 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAY22_05485 ENOG4105F38 ABC transporter, permease BAY22_05490 ENOG4105D38 putrescine abc transporter BAY22_05495 ENOG4105RBQ inner membrane protein ybjO BAY22_05550 ENOG4105E0A ABC, transporter BAY22_05555 ENOG410642S Nicotianamine synthase protein BAY22_05560 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) BAY22_05565 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BAY22_05570 ENOG4105DMR ABC, transporter BAY22_05575 ENOG4105GBT ABC transporter BAY22_05580 ENOG4106PMH Extracellular solute-binding protein family 3 BAY22_05585 ENOG4105E5Z arginine transporter ATP-binding subunit BAY22_05590 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BAY22_05595 ENOG41064MM (LipO)protein BAY22_05600 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BAY22_05605 ENOG4105CGD Nad-dependent epimerase dehydratase BAY22_05610 ENOG4105C5W Aldolase BAY22_05615 ENOG4105C7K acetolactate synthase BAY22_05620 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAY22_05630 ENOG4105DWU Membrane BAY22_05635 ENOG4105CPB ATP-dependent endonuclease of the OLD family BAY22_05640 ENOG4108MJ5 VirK protein BAY22_05645 ENOG4105DJY efflux transporter, rnd family, mfp subunit BAY22_05655 ENOG4105VEQ Cold shock protein BAY22_05665 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAY22_05670 ENOG4108RS6 transposase BAY22_05675 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BAY22_05685 ENOG4108JJ8 (ABC) transporter BAY22_05690 ENOG4108JJ9 ABC, transporter BAY22_05700 ENOG4105C3M thioredoxin reductase BAY22_05705 ENOG4105EW9 transcriptional regulator AsnC family BAY22_05710 ENOG4105CNU cell division protein FtsK BAY22_05720 ENOG4105D1H recombination factor protein RarA BAY22_05730 ENOG4108ISG Major Facilitator BAY22_05735 ENOG4105F1A Pyruvate formate-lyase BAY22_05745 ENOG4105C6N Formate acetyltransferase BAY22_05750 ENOG4105TMB Formate nitrite transporter BAY22_05755 ENOG4105DDY UPF0142 protein ycaO BAY22_05760 ENOG4105HDK L-asparaginase BAY22_05765 ENOG4105EUR Domain-Containing protein BAY22_05765 ENOG4105EUR Domain-Containing protein BAY22_05790 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BAY22_05800 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BAY22_05815 ENOG4105E32 cytoplasmic protein BAY22_05825 ENOG4105VEQ Cold shock protein BAY22_05830 ENOG4105W49 UPF0434 protein BAY22_05840 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BAY22_05850 ENOG4106371 Methyltransferase BAY22_05855 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BAY22_05860 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BAY22_05875 ENOG4108RS6 transposase BAY22_05880 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BAY22_05885 ENOG4105EAQ (twin-arginine translocation) pathway signal BAY22_05890 ENOG4105C5X domain protein BAY22_05895 ENOG4105CGF Aromatic amino acid aminotransferase BAY22_05915 ENOG4105CD8 aminopeptidase N BAY22_05925 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BAY22_05930 ENOG4105QVC MOSC domain-containing protein BAY22_05940 ENOG4105C5H ABC transporter BAY22_05945 ENOG4105F1S paraquat-inducible protein a BAY22_05950 ENOG4105DY2 Paraquat-inducible protein b BAY22_05955 ENOG4108Q2G (LipO)protein BAY22_05965 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) BAY22_05975 ENOG4108RS6 transposase BAY22_05995 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAY22_06010 ENOG4105DAN ATP-dependent protease BAY22_06020 ENOG4108RS6 transposase BAY22_06025 ENOG4105UYK outer membrane protein a BAY22_06035 ENOG4108RZ1 DNA transformation protein BAY22_06040 ENOG4105EM2 membrane BAY22_06045 ENOG410901E Membrane BAY22_06050 ENOG41088T4 Helicase IV BAY22_06060 ENOG4108Q67 UPF0319 protein BAY22_06065 ENOG4105K4P CoA-binding domain protein BAY22_06085 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BAY22_06095 ENOG4108BUD transposase BAY22_06130 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BAY22_06135 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAY22_06140 ENOG4105CHR reductase BAY22_06145 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BAY22_06155 ENOG4108KQ6 Enoyl-CoA hydratase BAY22_06160 ENOG4105CHR reductase BAY22_06170 ENOG41062T2 Acyl carrier protein BAY22_06175 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAY22_06205 ENOG4105CDV Ompa motb domain protein BAY22_06215 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAY22_06310 ENOG4105C5H ABC transporter BAY22_06325 ENOG4105D06 uba thif-type nad fad binding protein BAY22_06330 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAY22_06340 ENOG4105C19 ABC transporter BAY22_06345 ENOG4105ENT Efflux transporter rnd family, mfp subunit BAY22_06370 ENOG4105EGI Transcriptional regulator BAY22_06375 ENOG4105CBP Major Facilitator BAY22_06385 ENOG4105DHF Membrane BAY22_06400 ENOG4108HWV )-transporter BAY22_06405 ENOG4107GZ4 SanA protein BAY22_06420 ENOG41067MG lrgb family BAY22_06430 ENOG4105E5W Transporter BAY22_06465 ENOG4108RS6 transposase BAY22_06475 ENOG4105D1F ATP-binding protein BAY22_06495 ENOG4105EE5 Membrane protein terC BAY22_06500 ENOG4108819 ferric iron reductase BAY22_06505 ENOG4105DY8 decarboxylase BAY22_06510 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BAY22_06520 ENOG4105DUU IucA IucC family protein BAY22_06525 ENOG4105E0A ABC, transporter BAY22_06530 ENOG4105TVJ transport system, permease BAY22_06535 ENOG4105DQ5 transport system permease protein BAY22_06540 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BAY22_06545 ENOG4105CNM Receptor BAY22_06550 ENOG4105DUU IucA IucC family protein BAY22_06555 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAY22_06560 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAY22_06565 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAY22_06570 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BAY22_06585 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BAY22_06590 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BAY22_06600 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAY22_06610 ENOG4108535 NAD dependent epimerase/dehydratase family BAY22_06615 ENOG4105CNN ABC, transporter BAY22_06620 ENOG4105C2J ABC transporter BAY22_06625 ENOG4105C2J ABC transporter BAY22_06630 ENOG4107SCQ Iron-containing alcohol dehydrogenase BAY22_06640 ENOG4105CUB amino acid BAY22_06645 ENOG4105CJB Exodeoxyribonuclease I BAY22_06665 ENOG4105TNG K13735 adhesin invasin BAY22_06670 ENOG4105CSP Major Facilitator Superfamily BAY22_06675 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BAY22_06680 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BAY22_06690 ENOG4105DIA mandelate racemase muconate lactonizing BAY22_06705 ENOG4105UQX Mate efflux family protein BAY22_06725 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BAY22_06735 ENOG4108KX4 response regulator BAY22_06740 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BAY22_06750 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BAY22_06755 ENOG4108TSE Transferase BAY22_06770 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BAY22_06780 ENOG4105PVA Biofilm formation regulatory protein BssS BAY22_06800 ENOG41067V3 Antibiotic biosynthesis monooxygenase BAY22_06810 ENOG4107QQB Ribonuclease E BAY22_06815 ENOG4105EI2 Pseudouridine synthase BAY22_06820 ENOG4108RS6 transposase BAY22_06830 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BAY22_06835 ENOG4105VGS 50s ribosomal protein l32 BAY22_06850 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAY22_06855 ENOG4105CHR reductase BAY22_06865 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAY22_06870 ENOG4108RS6 transposase BAY22_06875 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BAY22_06880 ENOG4105HHA aminodeoxychorismate lyase BAY22_06890 ENOG4107QRG dna polymerase iii BAY22_06895 ENOG4105F8V Hydrolase, tatD family BAY22_06900 ENOG4105CI1 PTS System BAY22_06905 ENOG4108RS6 transposase BAY22_06915 ENOG4105K59 histidine triad (HIT) protein BAY22_06920 ENOG41090DQ Lipoprotein BAY22_06935 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) BAY22_06945 ENOG4105CEP NADH dehydrogenase BAY22_06975 ENOG4107MBR 17 kDa surface antigen BAY22_06980 ENOG4108JA2 transcriptioN-repair coupling factor BAY22_06985 ENOG4105D60 lipoprotein releasing system transmembrane protein BAY22_06995 ENOG4105D60 lipoprotein releasing system transmembrane protein BAY22_07005 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAY22_07015 ENOG4105EZE Cupin 4 family protein BAY22_07025 ENOG4105XJC Two component transcriptional regulator (Winged helix family BAY22_07035 ENOG4107QTF adenylosuccinate lyase BAY22_07055 ENOG4108R99 pseudouridine synthase BAY22_07060 ENOG4108HMX isocitrate dehydrogenase (NADP) BAY22_07065 ENOG4106NDP Transcriptional regulator BAY22_07075 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BAY22_07080 ENOG4105ECR NmrA family BAY22_07085 ENOG4105KVH Transcriptional regulator BAY22_07095 ENOG4105D6F Phosphatase BAY22_07100 ENOG41061EV selenium-binding protein YdfZ BAY22_07110 ENOG4108XM1 transcriptional regulator AsnC family BAY22_07115 ENOG4105GSJ Inner membrane protein ylaC BAY22_07130 ENOG4105VEQ Cold shock protein BAY22_07150 ENOG4105KT7 mgtC SapB transporter BAY22_07155 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BAY22_07165 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BAY22_07170 ENOG4107RD7 Flagellar Motor Protein, MotA BAY22_07180 ENOG4105CBS Chea signal transduction histidine kinase BAY22_07185 ENOG4108V3W Chemotaxis protein, CheW BAY22_07190 ENOG4105R9B Major Facilitator BAY22_07195 ENOG4105KME endoribonuclease L-psp BAY22_07205 ENOG4105WWK YheO domain protein BAY22_07225 ENOG4105C8Q Methyl-accepting chemotaxis BAY22_07230 ENOG4105C8Q Methyl-accepting chemotaxis BAY22_07235 ENOG4105C8Q Methyl-accepting chemotaxis BAY22_07240 ENOG4105BZU Histidine kinase BAY22_07250 ENOG4108VYJ response regulator receiver protein BAY22_07255 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BAY22_07265 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BAY22_07270 ENOG4105EUR Domain-Containing protein BAY22_07280 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAY22_07320 ENOG4105WT8 Protein of unknown function (DUF1480) BAY22_07335 ENOG4105GQR Chaperone BAY22_07355 ENOG4105DY2 Paraquat-inducible protein b BAY22_07360 ENOG4105H2K paraquat-inducible protein a BAY22_07365 ENOG4108ZGC gaf domain protein BAY22_07375 ENOG4105CN1 protease BAY22_07385 ENOG4105H8W Fimbrial protein BAY22_07390 ENOG4108VEV chaperone BAY22_07405 ENOG4108VEV chaperone BAY22_07410 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAY22_07415 ENOG4105CAZ oligogalacturonide lyase BAY22_07425 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BAY22_07430 ENOG4108ETY sodium dicarboxylate symporter BAY22_07435 ENOG4107K5X Membrane-bound metal-dependent hydrolase BAY22_07440 ENOG4108PU9 oligogalacturonate-specific porin BAY22_07445 ENOG4105WEM extracellular solute-binding protein BAY22_07455 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BAY22_07460 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BAY22_07465 ENOG41061NF Pectate lyase BAY22_07470 ENOG4105CHR reductase BAY22_07480 ENOG4105M5J Cupin 2, conserved barrel domain protein BAY22_07550 ENOG4105N4N Protein of unknown function (DUF2766) BAY22_07555 ENOG4105TIK BAY22_07560 ENOG41064PC BAY22_07590 ENOG410610J Protein of unknown function (DUF2627) BAY22_07595 ENOG4105VEQ Cold shock protein BAY22_07600 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAY22_07605 ENOG4105DHI Methyltransferase BAY22_07615 ENOG4105BZU Histidine kinase BAY22_07635 ENOG4105F3R pts system mannose fructose sorbose family iid BAY22_07640 ENOG4105ETZ PTS System BAY22_07645 ENOG4108EQA pts system BAY22_07650 ENOG4105EE5 Membrane protein terC BAY22_07655 ENOG4108V8F Transcriptional regulator, MarR family BAY22_07670 ENOG4105C26 Dehydrogenase BAY22_07675 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BAY22_07700 ENOG4105EFA 4-hydroxyphenylacetate BAY22_07705 ENOG4107UWN reductase BAY22_07710 ENOG4105EJQ L-serine dehydratase BAY22_07720 ENOG4105CRQ synthase (Component I) BAY22_07735 ENOG4105C1J atp-dependent rna helicase BAY22_07740 ENOG4105X2V dna damage-inducible protein BAY22_07755 ENOG4105CUG Oligopeptidase b BAY22_07765 ENOG4105MPK DNA polymerase III subunit theta BAY22_07770 ENOG41090A1 ferritin BAY22_07775 ENOG4105FXM Copper resistance protein BAY22_07785 ENOG4105NKT exported protein BAY22_07805 ENOG4105D00 flagellar biosynthetic protein flhB BAY22_07810 ENOG4105D7B Flagellar biosynthesis protein flha BAY22_07815 ENOG4105W13 flagellar protein BAY22_07825 ENOG4108RS6 transposase BAY22_07835 ENOG4105QVD Flagella synthesis protein FlgN BAY22_07840 ENOG4105M9M anti-sigma28 factor FlgM BAY22_07845 ENOG4105CKS Flagella basal body P-ring formation protein flgA BAY22_07850 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAY22_07855 ENOG4108ZC9 flagellar basal-body rod protein flgc BAY22_07860 ENOG4105W00 Flagellar hook capping protein BAY22_07865 ENOG4105BZE flagellar hook protein, FlgE BAY22_07870 ENOG4108KPB Flagellar basal-body rod protein FlgF BAY22_07890 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BAY22_07895 ENOG4105E1Q flagellar hook-associated protein BAY22_07900 ENOG4105DTJ flagellar hook-associated protein BAY22_07905 ENOG4105DKT Transcriptional regulator BAY22_07915 ENOG4105CNN ABC, transporter BAY22_07925 ENOG4105C2J ABC transporter BAY22_07935 ENOG4108MGF sugar kinase BAY22_07950 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BAY22_07955 ENOG4105VS8 Flagellar biosynthetic protein fliq BAY22_07960 ENOG4105CN7 Flagellar biosynthetic protein FliP BAY22_07970 ENOG4105DD5 Flagellar motor switch protein BAY22_07975 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAY22_07980 ENOG4107ZI8 flagellar basal body-associated protein flil BAY22_07985 ENOG4105WF4 Flagellar hook-length control protein BAY22_07990 ENOG4105GSA Flagellar export protein flij BAY22_07995 ENOG4108JIR Flagellum-specific ATP synthase BAY22_08000 ENOG41090PJ Flagellar assembly protein BAY22_08005 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAY22_08010 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BAY22_08015 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BAY22_08035 ENOG4105DHT Metal Dependent Phosphohydrolase BAY22_08040 ENOG4108T5G Adenylate BAY22_08060 ENOG4105MQ3 flagellar protein FliS BAY22_08065 ENOG4105DTS flagellar hook-associated BAY22_08070 ENOG4105I03 Flagellin BAY22_08075 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAY22_08080 ENOG4108M9K flagella biosynthesis protein FliZ BAY22_08085 ENOG4105K6H D-cysteine desulfhydrase BAY22_08090 ENOG4105EAB amino acid AbC transporter BAY22_08095 ENOG4105E5Q amino acid AbC transporter BAY22_08100 ENOG4105CDA abc transporter atp-binding protein BAY22_08115 ENOG4105C26 Dehydrogenase BAY22_08125 ENOG4105CK7 Sodium proline symporter BAY22_08140 ENOG4105DBE peroxidase BAY22_08155 ENOG4105C85 amino acid BAY22_08165 ENOG4108T1M outer membrane protein x BAY22_08180 ENOG4105RA2 Membrane BAY22_08185 ENOG4105XVG cytoplasmic protein BAY22_08190 ENOG4105WH1 Two component transcriptional regulator luxr family BAY22_08245 ENOG4108WC9 type VI secretion system effector, hcp1 family BAY22_08330 ENOG4105FDP GntR family transcriptional regulator BAY22_08340 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAY22_08355 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BAY22_08360 ENOG4108IJ9 (ABC) transporter BAY22_08410 ENOG4105CZE histidine utilization repressor BAY22_08415 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BAY22_08420 ENOG41090B9 response to stress BAY22_08430 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAY22_08435 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAY22_08440 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BAY22_08510 ENOG4108WF3 methyltransferase BAY22_08550 ENOG4105GR3 Histidine kinase BAY22_08560 ENOG4105ENX hydrolase BAY22_08605 ENOG4105C3G gtp-binding protein BAY22_08615 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BAY22_08625 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAY22_08655 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAY22_08660 ENOG4108YY7 Invasion gene expression up-regulator SirB BAY22_08665 ENOG41063JG Transcriptional regulator BAY22_08675 ENOG4108RS6 transposase BAY22_08680 ENOG4105CHH sulfate transporter BAY22_08720 ENOG4105EG2 ABC transporter, permease BAY22_08725 ENOG4105F38 ABC transporter, permease BAY22_08735 ENOG4108RS6 transposase BAY22_08740 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAY22_08745 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAY22_08765 ENOG4107XHZ cytoplasmic chaperone TorD family protein BAY22_08770 ENOG4105F3T (LipO)protein BAY22_08780 ENOG4105D9U N-acetyltransferase BAY22_08785 ENOG4105EP9 oxidoreductase BAY22_08810 ENOG4106ZCM YecM protein BAY22_08830 ENOG4105WJG Glutathione BAY22_08835 ENOG41081XQ Conserved Protein BAY22_08845 ENOG4108TIT dATP pyrophosphohydrolase BAY22_08870 ENOG4105FAV ABC, transporter BAY22_08880 ENOG4105NXV High-affinity zinc uptake system protein BAY22_08885 ENOG4105DR5 peptidase BAY22_08890 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BAY22_08895 ENOG4105CA9 Pyruvate kinase BAY22_08900 ENOG4106KNT transcriptional regulator BAY22_08905 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAY22_08910 ENOG4108UHU Aldolase BAY22_08925 ENOG4105M4H endoribonuclease L-psp BAY22_08930 ENOG4105DVT helicase BAY22_08935 ENOG41072GX Peptidase M22 Glycoprotease BAY22_08940 ENOG4105Y4Z Outer Membrane Lipoprotein BAY22_08945 ENOG4105CEY Amp-dependent synthetase and ligase BAY22_08950 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BAY22_08955 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BAY22_08960 ENOG4107QMS site-determining protein BAY22_08975 ENOG4105CVE Lytic murein transglycosylase BAY22_08980 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BAY22_08990 ENOG4107R08 Integrase BAY22_09015 ENOG4105NY2 NinB protein BAY22_09025 ENOG4105HRS Antitermination protein BAY22_09175 ENOG4108RS6 transposase BAY22_09250 ENOG4105UZW Tail fiber assembly protein BAY22_09270 ENOG4105C3J Cysteine desulfurase BAY22_09300 ENOG4105ED1 spovr family BAY22_09310 ENOG4105CNH Multidrug resistance protein MdtL BAY22_09315 ENOG4105EUB pirin domain protein BAY22_09320 ENOG4105HEI LysR family (Transcriptional regulator BAY22_09335 ENOG4105CYN Serine protein kinase BAY22_09340 ENOG4105GNX MltA-interacting MipA family protein BAY22_09345 ENOG4105DSB aldose 1-epimerase BAY22_09360 ENOG4105VUT cytoplasmic protein BAY22_09365 ENOG4108RWI nicotinamidase BAY22_09370 ENOG4105HDK L-asparaginase BAY22_09375 ENOG4105D07 Signal peptide peptidase, SppA BAY22_09380 ENOG41069NU Nitroreductase BAY22_09385 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) BAY22_09390 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAY22_09395 ENOG4105MTM Protein of unknown function (DUF1496) BAY22_09400 ENOG4105M6F mutator MutT protein BAY22_09405 ENOG4105CGK Exodeoxyribonuclease III BAY22_09410 ENOG4105SKE transcriptional Regulator LysR family BAY22_09435 ENOG4105CIY formyltetrahydrofolate deformylase BAY22_09445 ENOG4105I93 response regulator BAY22_09450 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAY22_09460 ENOG4107104 thymidine kinase BAY22_09475 ENOG4108EKI Dehydrogenase BAY22_09480 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BAY22_09485 ENOG4107QSI ABC, transporter BAY22_09495 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAY22_09500 ENOG4105C3U ABC transporter BAY22_09530 ENOG4108T1M outer membrane protein x BAY22_09545 ENOG4105K9H YciI-like protein BAY22_09550 ENOG410822N TonB family BAY22_09560 ENOG4105NAU thioesterase Superfamily protein BAY22_09590 ENOG4105EIF outer membrane protein W BAY22_09610 ENOG4105DK0 Indole-3-glycerol phosphate synthase BAY22_09620 ENOG4105DDQ anthranilate synthase BAY22_09640 ENOG4105DB7 PHP domain protein BAY22_09645 ENOG4107RTD sua5 ycio yrdc ywlc family protein BAY22_09650 ENOG4105FE9 pseudouridine synthase BAY22_09655 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BAY22_09660 ENOG4105UBK short-chain dehydrogenase reductase BAY22_09665 ENOG4105ERU peptidase BAY22_09670 ENOG4105RKX Protein of unknown function (DUF2498) BAY22_09680 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAY22_09685 ENOG4107R11 Transcriptional regulator BAY22_09695 ENOG4107QM5 aconitate hydratase BAY22_09700 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BAY22_09705 ENOG4105EYK Phosphatidylglycerophosphatase B BAY22_09710 ENOG4105Q4A inner membrane protein yciS BAY22_09715 ENOG4105CFV Tetratricopeptide repeat protein BAY22_09730 ENOG4108ZJT translation initiation factor, Sui1 BAY22_09735 ENOG41061RM osmotically inducible lipoprotein BAY22_09740 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BAY22_09750 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAY22_09755 ENOG4105VCD cytoplasmic protein BAY22_09760 ENOG4105D22 carbon starvation protein BAY22_09770 ENOG4105CSP Major Facilitator Superfamily BAY22_09775 ENOG4105EXW epimerase dehydratase BAY22_09780 ENOG4105CSM endonuclease III BAY22_09790 ENOG4108UQQ Electron transport complex BAY22_09795 ENOG4105D6A Electron transport complex BAY22_09800 ENOG4105UEI Transcriptional Regulator AraC Family BAY22_09820 ENOG4105M9B inner membrane protein ydgK BAY22_09825 ENOG4108JJA ABC, transporter BAY22_09830 ENOG4105BZ1 (ABC) transporter BAY22_09840 ENOG4105C42 Type I secretion membrane fusion protein (HlyD BAY22_09845 ENOG4108JJA ABC, transporter BAY22_09860 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BAY22_09870 ENOG4105CNN ABC, transporter BAY22_09880 ENOG4105D9R oxidoreductase BAY22_09885 ENOG4105DHU Bile acid BAY22_09915 ENOG4105EIP mannose-6-phosphate isomerase BAY22_09920 ENOG4105C9Q fumarate hydratase class II BAY22_09925 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) BAY22_09940 ENOG4105DAG ROK family BAY22_09945 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BAY22_09950 ENOG4105CMQ Chloride channel BAY22_10000 ENOG4105MQ5 zona occludens toxin BAY22_10060 ENOG4105MQ5 zona occludens toxin BAY22_10080 ENOG41060NJ transcriptional regulator BAY22_10090 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAY22_10095 ENOG4107UWC ABC, transporter BAY22_10100 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAY22_10105 ENOG4105FYV Amp nucleosidase BAY22_10130 ENOG4105C7K acetolactate synthase BAY22_10135 ENOG4105M71 acetolactate synthase 1 regulatory subunit BAY22_10140 ENOG4105PAD Hydrolase BAY22_10160 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAY22_10165 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BAY22_10170 ENOG4105Q9Y Universal stress protein BAY22_10175 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BAY22_10180 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BAY22_10190 ENOG4105C5D exported protein BAY22_10195 ENOG4105D5Q Arginine ornithine antiporter BAY22_10205 ENOG4107EXC regulatoR BAY22_10210 ENOG4105JJR Histidine kinase BAY22_10215 ENOG4105CTD carboxy-peptidase BAY22_10220 ENOG4108RS6 transposase BAY22_10245 ENOG4105DS1 cytochrome b561 BAY22_10260 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BAY22_10275 ENOG4105CQ7 ATP-dependent helicase BAY22_10285 ENOG4105DKT Transcriptional regulator BAY22_10290 ENOG4105DEI Mannitol dehydrogenase BAY22_10295 ENOG4105WXT Conserved Protein BAY22_10300 ENOG410689M (LipO)protein BAY22_10310 ENOG4105C5I Dehydrogenase BAY22_10315 ENOG41090X5 Heat shock protein hslJ BAY22_10325 ENOG4105KT7 mgtC SapB transporter BAY22_10360 ENOG4107QSI ABC, transporter BAY22_10365 ENOG4105KXI murein peptide amidase A BAY22_10370 ENOG4107S8C mandelate racemase muconate lactonizing BAY22_10375 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAY22_10380 ENOG4108RS6 transposase BAY22_10405 ENOG4105CM6 amino acid regulated cytosolic protein BAY22_10415 ENOG4105FM1 phage shock protein C BAY22_10420 ENOG4105YYT phage shock protein B BAY22_10425 ENOG41087YS Phage shock protein A BAY22_10430 ENOG4105E51 psp operon transcriptional activator BAY22_10435 ENOG4108RS6 transposase BAY22_10450 ENOG4108HIY periplasmic BAY22_10455 ENOG4108I5W peptide transport system, permease protein BAY22_10460 ENOG4108EU3 peptide transport system, permease BAY22_10465 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BAY22_10470 ENOG4108JQ2 peptide transport system atp-binding protein BAY22_10475 ENOG4105Q4T oxidoreductase BAY22_10480 ENOG4105DUX Transporter BAY22_10485 ENOG41069YE inner membrane protein yohC BAY22_10490 ENOG4108ZR5 Conserved Protein BAY22_10505 ENOG4108K3A Glutathione S-transferase BAY22_10525 ENOG410642K Lysozyme inhibitor BAY22_10535 ENOG4108XTF Outer Membrane Lipoprotein BAY22_10545 ENOG4107RGM aldo keto reductase BAY22_10550 ENOG4105XZD Fe-S protein BAY22_10555 ENOG4105DIJ Phosphoethanolamine transferase BAY22_10560 ENOG4108WUH Transcriptional regulator, TetR family BAY22_10565 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAY22_10575 ENOG4108UYE Lactoylglutathione lyase BAY22_10580 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) BAY22_10585 ENOG4105M2J Glutaredoxin BAY22_10595 ENOG4105K4H Nlp p60 protein BAY22_10600 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAY22_10610 ENOG4105F52 Transcriptional regulator BAY22_10615 ENOG4105CZQ inner membrane transport protein YdhC BAY22_10620 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BAY22_10625 ENOG4108R6K riboflavin synthase, subunit alpha BAY22_10645 ENOG4105CA9 Pyruvate kinase BAY22_10650 ENOG4105KMX major outer membrane lipoprotein BAY22_10655 ENOG4108RS6 transposase BAY22_10670 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BAY22_10685 ENOG4105JRK feS assembly protein SufD BAY22_10690 ENOG4105C3K feS assembly ATPase SufC BAY22_10695 ENOG4105DIW FeS assembly protein SUFB BAY22_10700 ENOG4108Z4V iron-sulfur cluster assembly BAY22_10710 ENOG4105KA0 thioesterase Superfamily protein BAY22_10715 ENOG4105CQB FAD linked oxidase domain protein BAY22_10720 ENOG4105IPI Membrane BAY22_10730 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAY22_10740 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BAY22_10755 ENOG4108QBX (LipO)protein BAY22_10795 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BAY22_10800 ENOG4108V06 Glutathione peroxidase BAY22_10815 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BAY22_10820 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAY22_10825 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BAY22_10850 ENOG41087WU BAY22_10875 ENOG4105DSE periplasmic solute binding protein BAY22_10880 ENOG4105DIK (ABC) transporter BAY22_10885 ENOG4105CC5 ABC transporter BAY22_10890 ENOG4105CC5 ABC transporter BAY22_10900 ENOG4105FGM Fructosamine kinase BAY22_10905 ENOG4107PN8 YfeABCD locus regulator BAY22_10910 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BAY22_10930 ENOG4105DSF transport protein BAY22_10960 ENOG4107YC3 synthase BAY22_10965 ENOG4105VJY transcriptional regulator BAY22_10970 ENOG4105ETT transcriptional Regulator, LysR family BAY22_10980 ENOG4105C54 Major Facilitator superfamily BAY22_10990 ENOG4105CPC Aldo Keto reductase BAY22_10995 ENOG4108Y1S CRISPR-associated protein, Csy4 family BAY22_11000 ENOG4105M6W Crispr-associated protein, Csy3 family BAY22_11005 ENOG4105DZX CRISPR-associated protein, Csy2 family BAY22_11010 ENOG4105ENG CRISPR-associated protein, Csy1 family BAY22_11020 ENOG4107IIZ CRISPR-associated helicase, Cas3 BAY22_11025 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BAY22_11030 ENOG4105CUY Mechanosensitive ion channel BAY22_11050 ENOG4105HY2 Glycosidase related protein BAY22_11055 ENOG4105DRS transport system, permease BAY22_11070 ENOG4105ETE Transcriptional regulator (LacI family BAY22_11080 ENOG4108IJ9 (ABC) transporter BAY22_11090 ENOG4105CKT filamentous hemagglutinin BAY22_11110 ENOG4105CKT filamentous hemagglutinin BAY22_11135 ENOG4105D5K Hemolysin activator protein BAY22_11140 ENOG4105E3J oxidoreductase BAY22_11145 ENOG4105DVW rieske (2Fe-2S) BAY22_11150 ENOG4105C94 Transporter BAY22_11155 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAY22_11160 ENOG4105EJC lysr family transcriptional regulator BAY22_11165 ENOG4105FKQ transcriptional regulator BAY22_11175 ENOG4105C2J ABC transporter BAY22_11180 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAY22_11185 ENOG4105CPQ Dehydrogenase BAY22_11205 ENOG4108T1M outer membrane protein x BAY22_11235 ENOG4107R0W ABC transporter BAY22_11240 ENOG4105E5Q amino acid AbC transporter BAY22_11245 ENOG4105CDA abc transporter atp-binding protein BAY22_11250 ENOG4107SDU Methyl-accepting chemotaxis BAY22_11270 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BAY22_11275 ENOG4108MTB glycosyl transferase family BAY22_11280 ENOG4105CEY Amp-dependent synthetase and ligase BAY22_11290 ENOG4108IPT Naphthoate synthase BAY22_11305 ENOG4105E4F Isochorismate synthase BAY22_11315 ENOG4105TNS Conserved Protein BAY22_11330 ENOG4105C01 Dihydroxy-acid dehydratase BAY22_11345 ENOG4105C5I Dehydrogenase BAY22_11355 ENOG4105K2J Transcriptional regulator BAY22_11360 ENOG4105F32 YngK protein BAY22_11365 ENOG4105CHR reductase BAY22_11370 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BAY22_11375 ENOG4108R66 Conserved Protein BAY22_11390 ENOG4105C8S subunit m BAY22_11395 ENOG4105D65 subunit l BAY22_11405 ENOG4107UFS subunit j BAY22_11420 ENOG4108IEH NADH dehydrogenase subunit g BAY22_11425 ENOG4107QIZ NADH dehydrogenase BAY22_11430 ENOG4105GKE subunit e BAY22_11440 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAY22_11450 ENOG4107NQ8 LysR family Transcriptional regulator BAY22_11460 ENOG4105CHM Aminotransferase BAY22_11475 ENOG4107QWE )-transporter BAY22_11480 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BAY22_11505 ENOG4105C6K Malic enzyme BAY22_11510 ENOG4107P2S Transcriptional regulator BAY22_11530 ENOG4108JQB penicillin-binding protein 1C BAY22_11535 ENOG4105DN3 alpha-2-macroglobulin domain protein BAY22_11550 ENOG4105C26 Dehydrogenase BAY22_11555 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BAY22_11565 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAY22_11570 ENOG4105C2J ABC transporter BAY22_11575 ENOG4105CNN ABC, transporter BAY22_11580 ENOG4105CK5 oxidoreductase BAY22_11585 ENOG4105EDK PfkB domain protein BAY22_11595 ENOG4105DH8 myo-inositol catabolism BAY22_11605 ENOG4108JJ7 ABC transporter BAY22_11630 ENOG4108N8T regulatoR BAY22_11640 ENOG4105VEQ Cold shock protein BAY22_11645 ENOG4107Z6W Protein CrcB homolog BAY22_11655 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BAY22_11675 ENOG4105DZ1 carboxypeptidase BAY22_11685 ENOG4105CNI cell division protein FtsW BAY22_11690 ENOG4105CJN penicillin-binding protein BAY22_11700 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BAY22_11710 ENOG4105DJF DNA polymerase III, delta' subunit BAY22_11725 ENOG4107PAI alpha helical protein BAY22_11730 ENOG4105CDA abc transporter atp-binding protein BAY22_11735 ENOG4105DRP amino acid AbC transporter BAY22_11740 ENOG4105EAD ABC transporter BAY22_11745 ENOG4107RP9 extracellular solute-binding protein, family 3 BAY22_11750 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BAY22_11755 ENOG4108JU5 Magnesium and cobalt efflux protein BAY22_11765 ENOG4105C9A Phoh family BAY22_11775 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BAY22_11810 ENOG4105CAQ asparagine synthetase BAY22_11815 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAY22_11820 ENOG4105E2R ROK family BAY22_11825 ENOG4105CE4 GlcNAc 6-P deacetylase BAY22_11835 ENOG4105CI1 PTS System BAY22_11840 ENOG4108RS6 transposase BAY22_11860 ENOG41090R7 Ferric uptake BAY22_11865 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BAY22_11870 ENOG4105NNH LexA regulated protein BAY22_11880 ENOG4105EV9 Alpha Beta Hydrolase BAY22_11920 ENOG4105GIJ Glycine betaine BAY22_11925 ENOG4108HQS Glycine betaine BAY22_11930 ENOG4108IJ7 Glycine betaine BAY22_11935 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAY22_11960 ENOG4108WMJ Protein of unknown function (DUF2002) BAY22_11965 ENOG4108SAJ Protein of unknown function (DUF1198) BAY22_11980 ENOG4105VEQ Cold shock protein BAY22_11985 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BAY22_11990 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAY22_11995 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAY22_12000 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BAY22_12005 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BAY22_12035 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) BAY22_12055 ENOG4105XXV Acid-resistance protein BAY22_12065 ENOG4107SVH Potassium channel protein BAY22_12070 ENOG41086WQ Protein CrcB homolog BAY22_12075 ENOG41085Q9 Protein CrcB homolog BAY22_12085 ENOG4105VZJ PTS System BAY22_12090 ENOG4105CK1 PTS System BAY22_12095 ENOG4105VCP PTS System BAY22_12100 ENOG4105EZV Transcriptional regulator BAY22_12125 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BAY22_12145 ENOG4105EEX Two component transcriptional regulator (Winged helix family BAY22_12150 ENOG4105C08 Histidine kinase BAY22_12180 ENOG4105XIQ Protein of unknown function (DUF2517) BAY22_12185 ENOG4107SEY Conserved Protein BAY22_12190 ENOG4105CVP deoxyribo-dipyrimidine photolyase BAY22_12195 ENOG4107RF4 Phosphodiesterase BAY22_12200 ENOG4107QNR UPF0135 protein BAY22_12210 ENOG4107R7A Allophanate hydrolase subunit 2 BAY22_12260 ENOG4105C1J atp-dependent rna helicase BAY22_12270 ENOG4108IYU L-aspartate oxidase BAY22_12280 ENOG41069PW sigma-e factor negative regulatory protein BAY22_12285 ENOG4105VQK sigma E regulatory protein, MucB RseB BAY22_12290 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BAY22_12305 ENOG4105C3F Signal peptidase i BAY22_12345 ENOG4105CS6 Rhs element vgr protein BAY22_12375 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BAY22_12385 ENOG4108V0P LemA family BAY22_12405 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BAY22_12410 ENOG41060IM Heme exporter protein BAY22_12415 ENOG4105X3C heme exporter protein BAY22_12425 ENOG4105DA4 cytochrome c-type biogenesis protein BAY22_12430 ENOG4107QX9 Thiol disulfide interChange protein BAY22_12435 ENOG4105KWW Biogenesis protein BAY22_12440 ENOG4105KWW Biogenesis protein BAY22_12445 ENOG410903C (LipO)protein BAY22_12450 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BAY22_12455 ENOG4105KZW UPF0381 protein BAY22_12470 ENOG4108BY2 phosphohistidine phosphatase BAY22_12480 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BAY22_12490 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) BAY22_12495 ENOG4105EJ9 Membrane BAY22_12500 ENOG4108BPE -transporting atpase BAY22_12505 ENOG4105MH2 YfcL protein BAY22_12515 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAY22_12530 ENOG4106WZ1 flagella biosynthesis regulator BAY22_12535 ENOG410631K Membrane BAY22_12555 ENOG4108RS6 transposase BAY22_12560 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAY22_12570 ENOG4105DQR SNARE associated Golgi BAY22_12580 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAY22_12585 ENOG4108S3P Sporulation domain protein BAY22_12590 ENOG4105E96 Colicin v production protein BAY22_12595 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BAY22_12600 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BAY22_12605 ENOG4105E89 ABC transporter BAY22_12610 ENOG4105DSP amino acid AbC transporter BAY22_12615 ENOG4106YG3 ABC transporter BAY22_12620 ENOG4108JEH abc transporter atp-binding protein BAY22_12625 ENOG4105ECP epimerase BAY22_12635 ENOG4108RE9 Phosphodiesterase BAY22_12640 ENOG4105PTV Nudix Hydrolase BAY22_12645 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BAY22_12655 ENOG4108JQB penicillin-binding protein 1C BAY22_12660 ENOG4105HVQ Regulatory factor of maltose metabolism BAY22_12685 ENOG4108WC9 type VI secretion system effector, hcp1 family BAY22_12710 ENOG4105EZE Cupin 4 family protein BAY22_12730 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BAY22_12755 ENOG4107SET aldo keto reductase BAY22_12760 ENOG4105EQ2 LysR family Transcriptional regulator BAY22_12790 ENOG41077RS Phosphatase BAY22_12795 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAY22_12805 ENOG4108HPI phosphatidate Cytidylyltransferase BAY22_12810 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BAY22_12860 ENOG4105WQ3 Rna-binding protein BAY22_12865 ENOG4108RS6 transposase BAY22_12880 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAY22_12885 ENOG4108MK9 spermidine N(1)-acetyltransferase BAY22_12890 ENOG4108C80 FliB family BAY22_12895 ENOG4108C80 FliB family BAY22_12905 ENOG4105E2Z phosphate ABC transporter (Permease BAY22_12910 ENOG4105C8U phosphate abc transporter BAY22_12915 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BAY22_12920 ENOG4105C9X ppx gppa phosphatase BAY22_12930 ENOG4105CJW magnesium transporter BAY22_12935 ENOG4105R8A Heat shock protein BAY22_12940 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BAY22_12945 ENOG4105F38 ABC transporter, permease BAY22_12955 ENOG4108JPW Aminotransferase BAY22_12965 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAY22_12990 ENOG4105EB3 Histidine kinase BAY22_12995 ENOG4105EB3 Histidine kinase BAY22_13000 ENOG4105E3W Two component transcriptional regulator (Winged helix family BAY22_13005 ENOG4105KWI UPF0339 protein BAY22_13010 ENOG4105CFP Peptidase U32 BAY22_13020 ENOG4108ZGU inhibitor of vertebrate lysozyme BAY22_13030 ENOG4105DWF phosphomethylpyrimidine kinase BAY22_13075 ENOG4108WC9 type VI secretion system effector, hcp1 family BAY22_13080 ENOG4108RS6 transposase BAY22_13095 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAY22_13105 ENOG4105VPD cellular component movement BAY22_13120 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BAY22_13125 ENOG4105N21 Membrane BAY22_13170 ENOG4108MGN ATP-binding component of a transport system BAY22_13175 ENOG4108MGN ATP-binding component of a transport system BAY22_13185 ENOG4105YYA enhanced serine sensitivity protein SseB BAY22_13195 ENOG4105WVQ Fe-S assembly protein IscX BAY22_13200 ENOG4108ZIT Ferredoxin, 2FE-2S BAY22_13205 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB BAY22_13220 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BAY22_13225 ENOG4105C3J Cysteine desulfurase BAY22_13245 ENOG4108RS6 transposase BAY22_13250 ENOG4105D7X high-affinity nickel-transporter BAY22_13255 ENOG41065CD Exported protein BAY22_13260 ENOG4108MN2 Stationary phase inducible protein CsiE BAY22_13265 ENOG4105D8G Major Facilitator superfamily BAY22_13285 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAY22_13290 ENOG4108M21 BAY22_13295 ENOG4108M21 BAY22_13300 ENOG4108YZA Nitrogen regulatory protein pii BAY22_13305 ENOG4105C4K Nad synthetase BAY22_13310 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAY22_13315 ENOG4108SKK alpha helix protein BAY22_13320 ENOG4107WP9 Histidine kinase BAY22_13325 ENOG4108RS6 transposase BAY22_13355 ENOG4108Z6B deaminase BAY22_13360 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BAY22_13370 ENOG4106G6Q Transcriptional regulator BAY22_13375 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BAY22_13380 ENOG4108RS6 transposase BAY22_13390 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BAY22_13440 ENOG4105CW0 outer membrane usher protein BAY22_13450 ENOG4105CW0 outer membrane usher protein BAY22_13455 ENOG4105GQR Chaperone BAY22_13465 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAY22_13515 ENOG4105CVE Lytic murein transglycosylase BAY22_13540 ENOG4108WC9 type VI secretion system effector, hcp1 family BAY22_13550 ENOG4107QY8 reductase BAY22_13555 ENOG4105QAX Iron-sulfur BAY22_13560 ENOG4107KGK dmso reductase anchor subunit BAY22_13565 ENOG4108NEM leader-binding protein dmsD BAY22_13575 ENOG4107Y60 (LipO)protein BAY22_13585 ENOG4106B0W Curli production assembly transport component CsgG BAY22_13595 ENOG4108VKM cytochrome b561 BAY22_13600 ENOG4105CHM Aminotransferase BAY22_13605 ENOG41072TH Protein of unknown function (DUF1479) BAY22_13620 ENOG4105C5Q Transcriptional regulator BAY22_13625 ENOG4105CPC Aldo Keto reductase BAY22_13640 ENOG4105D9N nucleoside BAY22_13680 ENOG4108RS6 transposase BAY22_13705 ENOG4105VRT cytoplasmic protein BAY22_13720 ENOG4105EXN Sulfate transport protein CysZ BAY22_13725 ENOG4105C6T cysteine synthase BAY22_13730 ENOG4105KZ7 phosphocarrier protein hpr BAY22_13740 ENOG4105C5Y PTS System BAY22_13745 ENOG4108RS6 transposase BAY22_13755 ENOG4105E0F Histidine kinase BAY22_13760 ENOG4105E3W Two component transcriptional regulator (Winged helix family BAY22_13765 ENOG4105DJY efflux transporter, rnd family, mfp subunit BAY22_13780 ENOG4105E1V na solute symporter BAY22_13790 ENOG4107RAQ aminopeptidase BAY22_13800 ENOG4105C87 Aminotransferase class I and II BAY22_13810 ENOG41062D9 Histidine kinase BAY22_13815 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAY22_13825 ENOG4105C6T cysteine synthase BAY22_13830 ENOG4108IJ6 ABC transporter BAY22_13835 ENOG4105ECW sulfate abc transporter BAY22_13840 ENOG4108I5D sulfate abc transporter BAY22_13845 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BAY22_13855 ENOG4105QEK Transcriptional regulator BAY22_13865 ENOG4108R66 Conserved Protein BAY22_13890 ENOG4105EZR dyp-type peroxidase family protein BAY22_13895 ENOG4105E7K (LipO)protein BAY22_13900 ENOG4105H4F exported protein BAY22_13935 ENOG4105C6K Malic enzyme BAY22_13945 ENOG4105CUW cytochrome C-TYPE protein BAY22_13950 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BAY22_13960 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BAY22_13965 ENOG4108ZNS ferredoxin-type protein NapF BAY22_13970 ENOG4105WH1 Two component transcriptional regulator luxr family BAY22_13980 ENOG4105BZS acriflavin resistance protein BAY22_13990 ENOG4105S2T inner membrane protein YbcI BAY22_13995 ENOG4105C4X radical SAM domain protein BAY22_14000 ENOG4105ENH Sulfatase BAY22_14005 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAY22_14010 ENOG4107Z33 ABC transporter, permease BAY22_14015 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BAY22_14025 ENOG4105KUZ arsenate reductase BAY22_14055 ENOG4105CGZ zinc metallopeptidase BAY22_14065 ENOG4108RS6 transposase BAY22_14070 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BAY22_14080 ENOG4105RH4 Glycine cleavage system transcriptional repressor BAY22_14085 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAY22_14105 ENOG4105C02 permease BAY22_14110 ENOG4105ERG peptidase m48, ste24p BAY22_14115 ENOG4105K89 arsenate reductase BAY22_14125 ENOG4108RS6 transposase BAY22_14140 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BAY22_14150 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAY22_14155 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAY22_14160 ENOG4105CV6 ABC transporter, permease BAY22_14165 ENOG4108I0Y (ABC) transporter BAY22_14170 ENOG4108UJV acyl-CoA thioesterase i BAY22_14175 ENOG4105E1F short-chain dehydrogenase reductase BAY22_14180 ENOG4107QR8 Thioredoxin BAY22_14185 ENOG4107QX8 SPFH domain, Band 7 family protein BAY22_14190 ENOG4105G5H Membrane BAY22_14195 ENOG4108Z6Z Transcriptional regulator BAY22_14205 ENOG4105MBR gumn family BAY22_14210 ENOG4108Z66 YbaK ebsC protein BAY22_14220 ENOG4105CGH 5'-nucleotidase BAY22_14225 ENOG4105CGH 5'-nucleotidase BAY22_14230 ENOG4105CGH 5'-nucleotidase BAY22_14235 ENOG4105EU0 Major facilitator Superfamily BAY22_14240 ENOG4105CKD glutathione-regulated potassium-efflux system protein BAY22_14245 ENOG4107RE1 Inosine-guanosine kinase BAY22_14250 ENOG4108QY5 Ferric enterobactin transport protein BAY22_14265 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BAY22_14280 ENOG4108TJN glycosyl transferase group 1 BAY22_14310 ENOG4108SMP Nad-dependent epimerase dehydratase BAY22_14315 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAY22_14320 ENOG4105FAW cDP-glucose 4,6-dehydratase BAY22_14325 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BAY22_14330 ENOG4108EX3 reductase BAY22_14360 ENOG4107QMP dna polymerase iii subunits gamma and tau BAY22_14390 ENOG4106428 Protein of unknown function (DUF2496) BAY22_14395 ENOG4105EGS Mechanosensitive ion channel BAY22_14400 ENOG41090EX DsrE family BAY22_14405 ENOG4108IG5 Transcriptional regulator BAY22_14410 ENOG4105C1P efflux transporter, rnd family, mfp subunit BAY22_14415 ENOG4105BZS acriflavin resistance protein BAY22_14425 ENOG4105YK5 50S ribosomal protein L36 BAY22_14435 ENOG4108UKR Biofilm formation regulator YbaJ BAY22_14440 ENOG4105KF5 hemolysin expression-modulating protein BAY22_14450 ENOG41080UX Methyltransferase BAY22_14455 ENOG4108MNP Glycoprotein polysaccharide metabolism BAY22_14460 ENOG4105C29 acyl-CoA thioesterase BAY22_14465 ENOG4105BZU Histidine kinase BAY22_14470 ENOG4108YZA Nitrogen regulatory protein pii BAY22_14475 ENOG4105BZ1 (ABC) transporter BAY22_14480 ENOG4105BZ1 (ABC) transporter BAY22_14485 ENOG4108XM1 transcriptional regulator AsnC family BAY22_14490 ENOG4105C6T cysteine synthase BAY22_14500 ENOG4108NFA extracellular solute-binding protein BAY22_14510 ENOG4108TGP Thioesterase superfamily protein BAY22_14515 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BAY22_14520 ENOG4105EIN peptidylprolyl cis-trans isomerase BAY22_14525 ENOG4105K70 DNA-binding protein BAY22_14530 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BAY22_14555 ENOG4105M85 Bola protein BAY22_14560 ENOG4105IEY (LipO)protein BAY22_14565 ENOG4105EYM Major Facilitator superfamily BAY22_14570 ENOG4108NFH Sugar hydrolase BAY22_14575 ENOG4105E2S oxidase) subunit II BAY22_14580 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAY22_14585 ENOG4105CCU oxidase (Subunit III) BAY22_14590 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BAY22_14600 ENOG4107RDB Major Facilitator BAY22_14610 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAY22_14615 ENOG4107S0N DJ-1 family BAY22_14635 ENOG4105CTB Polyprenyl synthetase BAY22_14645 ENOG4108RS6 transposase BAY22_14650 ENOG4108ZAI phosphatidylglycerophosphatase a BAY22_14655 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BAY22_14670 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BAY22_14690 ENOG4108RS6 transposase BAY22_14695 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAY22_14700 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAY22_14705 ENOG4105VIE preprotein translocase, subunit YajC BAY22_14715 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BAY22_14720 ENOG4108ZYK Acyl carrier protein phosphodiesterase BAY22_14725 ENOG4105D3R alkyl hydroperoxide reductase BAY22_14730 ENOG4108RS6 transposase BAY22_14750 ENOG4105CHR reductase BAY22_14755 ENOG4107R28 alpha amylase, catalytic region BAY22_14760 ENOG4105C85 amino acid BAY22_14765 ENOG4105CWM branched-chain amino acid transport system II carrier protein BAY22_14775 ENOG4105BZU Histidine kinase BAY22_14780 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAY22_14790 ENOG4107RH8 nuclease SbcCD subunit D BAY22_14795 ENOG4105EYH Exonuclease BAY22_14815 ENOG4105DKQ ROK family BAY22_14910 ENOG4105CIN aminoacyl-histidine dipeptidase BAY22_14930 ENOG4105CJ2 (LipO)protein BAY22_14950 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BAY22_14955 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BAY22_14960 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BAY22_14965 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BAY22_14970 ENOG4105E7A Glutamine amidotransferase BAY22_14980 ENOG4107QPN acyl-Coa dehydrogenase BAY22_14990 ENOG4106YJS accessory processing protein BAY22_15015 ENOG4105C5R Aminotransferase BAY22_15030 ENOG4105C5R Aminotransferase BAY22_15040 ENOG4105E5Q amino acid AbC transporter BAY22_15080 ENOG4105EQ0 Major Facilitator superfamily BAY22_15085 ENOG4108UMN azlc family BAY22_15090 ENOG4105ZED uncharacterized protein ygaH BAY22_15095 ENOG4105NTK Transcriptional repressor Mpra BAY22_15100 ENOG4105CW7 secretion protein, HlyD family BAY22_15105 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAY22_15110 ENOG4105EIB trna rrna methyltransferase BAY22_15115 ENOG4105K63 Thioredoxin BAY22_15120 ENOG4106IUH DTW domain containing protein BAY22_15125 ENOG4105CD5 CoA-binding domain protein BAY22_15130 ENOG4105JIM Phosphatidylserine synthase BAY22_15135 ENOG4105T42 (LipO)protein BAY22_15170 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAY22_15175 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAY22_15180 ENOG4105C34 Pseudouridine synthase BAY22_15185 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BAY22_15190 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BAY22_15195 ENOG4108RS6 transposase BAY22_15220 ENOG4105EHE chorismate mutase- prephenate dehydrogenase BAY22_15225 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BAY22_15230 ENOG4108NEV two component transcriptional regulator, LytTR family BAY22_15235 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BAY22_15240 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BAY22_15245 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BAY22_15250 ENOG4108NE3 Salt-induced outer membrane protein BAY22_15255 ENOG4108RS6 transposase BAY22_15280 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BAY22_15285 ENOG4106KVJ cytochrome C assembly protein BAY22_15290 ENOG4108JU6 CBS domain protein BAY22_15295 ENOG4108RS6 transposase BAY22_15300 ENOG4108RS6 transposase BAY22_15310 ENOG4105D9M gamma-glutamylcysteine synthetase BAY22_15315 ENOG4105W39 Membrane BAY22_15320 ENOG4107VXZ Hydrolase BAY22_15350 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BAY22_15355 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAY22_15390 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BAY22_15395 ENOG4108IUS Transketolase BAY22_15400 ENOG4108HHA Transketolase BAY22_15405 ENOG4105CNN ABC, transporter BAY22_15410 ENOG4105C2J ABC transporter BAY22_15430 ENOG4108XVM Cytochrome b(562) BAY22_15435 ENOG4105CPW cytochrome b561 BAY22_15440 ENOG4108NEM leader-binding protein dmsD BAY22_15445 ENOG4107KGK dmso reductase anchor subunit BAY22_15450 ENOG4105QAX Iron-sulfur BAY22_15455 ENOG4107QY8 reductase BAY22_15460 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BAY22_15465 ENOG4105E98 transcriptional regulator DeoR family BAY22_15475 ENOG4108RS6 transposase BAY22_15480 ENOG4105C2J ABC transporter BAY22_15485 ENOG4105CNN ABC, transporter BAY22_15490 ENOG4105F5R ABC transporter BAY22_15495 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BAY22_15500 ENOG4105CMG Carbohydrate kinase BAY22_15505 ENOG4107GFK fumarate BAY22_15515 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAY22_15530 ENOG4105D05 Receptor BAY22_15540 ENOG4105CA0 peroxidase BAY22_15545 ENOG4105E89 ABC transporter BAY22_15570 ENOG4105DKT Transcriptional regulator BAY22_15580 ENOG4105CMT Dihydroxyacetone kinase BAY22_15585 ENOG4105CHR reductase BAY22_15590 ENOG4105CPQ Dehydrogenase BAY22_15595 ENOG4108YZG isomerase BAY22_15605 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BAY22_15610 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAY22_15615 ENOG4108K5P (LipO)protein BAY22_15640 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BAY22_15650 ENOG4105N0Z inner membrane protein ygbE BAY22_15655 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BAY22_15705 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BAY22_15710 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAY22_15730 ENOG4105DXN mazG family BAY22_15740 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAY22_15745 ENOG4105BZU Histidine kinase BAY22_15750 ENOG4105C0H protease BAY22_15760 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BAY22_15770 ENOG4105EN6 Membrane BAY22_15790 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAY22_15795 ENOG4105J76 Periplasmic binding protein BAY22_15805 ENOG4105E0A ABC, transporter BAY22_15810 ENOG4105BZ4 penicillin-binding protein BAY22_15815 ENOG4105CQ7 ATP-dependent helicase BAY22_15820 ENOG4107XID 2'-5' rna ligase BAY22_15830 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BAY22_15835 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) BAY22_15840 ENOG4105DJ0 Poly(A) Polymerase BAY22_15845 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAY22_15865 ENOG4107BJW polysaccharide deacetylase BAY22_15870 ENOG4105E3A (ABC) transporter BAY22_15875 ENOG4105DA5 (ABC) transporter BAY22_15880 ENOG41077A9 carbonic anhydrase BAY22_15885 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAY22_15890 ENOG4105E3B Multicopper oxidase BAY22_15895 ENOG4108ZRK uncharacterized protein yacC BAY22_15910 ENOG4105RPH Inner membrane protein YddG BAY22_15920 ENOG4107QIJ Aconitate hydratase 2 BAY22_15925 ENOG4108RS6 transposase BAY22_15930 ENOG4107QN2 dihydrolipoyl dehydrogenase BAY22_15935 ENOG4107QSN dihydrolipoamide acetyltransferase BAY22_15940 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BAY22_15945 ENOG41073TP transcriptional regulator BAY22_15950 ENOG4105C85 amino acid BAY22_15955 ENOG4106A72 regulatory protein AmpE BAY22_15960 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BAY22_15965 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAY22_15970 ENOG4108ZUW Major pilin subunit BAY22_15975 ENOG4107QHF type ii secretion system protein e BAY22_15980 ENOG4105D7Q type ii secretion system BAY22_15995 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAY22_16010 ENOG4108RS6 transposase BAY22_16025 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BAY22_16045 ENOG4108K5H permease YjgP YjgQ family protein BAY22_16050 ENOG4108M8S permease YjgP YjgQ family protein BAY22_16060 ENOG4105MYG DNA polymerase iii, chi subunit BAY22_16065 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAY22_16070 ENOG4108MJ3 acetyltransferase BAY22_16075 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BAY22_16080 ENOG4105DBV ornithine carbamoyltransferase BAY22_16085 ENOG4105XEP YhcH YjgK YiaL family protein BAY22_16095 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAY22_16100 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAY22_16105 ENOG4105C3U ABC transporter BAY22_16110 ENOG4108JQ7 (ABC) transporter BAY22_16115 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BAY22_16120 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BAY22_16125 ENOG4107RJJ Transcriptional regulator BAY22_16130 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BAY22_16135 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BAY22_16140 ENOG4105EKV Phosphonate metabolism protein BAY22_16145 ENOG4105FT8 Phosphonate metabolism BAY22_16150 ENOG4105ENV phosphonate C-P lyase system protein PhnK BAY22_16155 ENOG4105HRV phosphonate c-p lyase system protein phnl BAY22_16160 ENOG4105FD8 phosphonate metabolism protein PhnM BAY22_16165 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BAY22_16170 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BAY22_16175 ENOG4105K4T epimerase BAY22_16195 ENOG4105DRS transport system, permease BAY22_16200 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BAY22_16225 ENOG4108YYD acetyltransferase BAY22_16230 ENOG4105XPQ lipid carrier protein BAY22_16240 ENOG4105CFP Peptidase U32 BAY22_16245 ENOG4106RZ4 Peptidase U32 BAY22_16250 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BAY22_16255 ENOG4105BZS acriflavin resistance protein BAY22_16265 ENOG4105DEN Luciferase family BAY22_16285 ENOG4105C1J atp-dependent rna helicase BAY22_16300 ENOG4105DQ6 Transposase BAY22_16330 ENOG4105CHV Transcription elongation factor NusA BAY22_16360 ENOG4105EEI dihydropteroate synthase BAY22_16365 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAY22_16375 ENOG4105HBR Rna-binding protein BAY22_16380 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BAY22_16385 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BAY22_16405 ENOG4105QYV Membrane BAY22_16420 ENOG4105EAH synthase BAY22_16430 ENOG4105HVQ Regulatory factor of maltose metabolism BAY22_16450 ENOG4105DFU Cell wall formation (By similarity) BAY22_16460 ENOG4105F0N pyrophosphate phospho-hydrolase BAY22_16465 ENOG4108ZHD aig2 family BAY22_16475 ENOG4105CFU surface antigen BAY22_16485 ENOG4105C37 (CBS) domain BAY22_16490 ENOG41061GZ Protein of unknown function (DUF1107) BAY22_16495 ENOG4108UUE Transcriptional regulator BAY22_16500 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BAY22_16505 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BAY22_16515 ENOG4108V1T peptidylprolyl cis-trans isomerase BAY22_16520 ENOG4105FHY Opacity-associated protein A BAY22_16530 ENOG4108RS6 transposase BAY22_16540 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BAY22_16550 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BAY22_16560 ENOG4108MXZ Esterase BAY22_16580 ENOG4105CWB LysR family transcriptional Regulator BAY22_16585 ENOG4108CNN domain protein BAY22_16595 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAY22_16615 ENOG4105W4M Transport-associated protein BAY22_16625 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BAY22_16635 ENOG4105BZU Histidine kinase BAY22_16645 ENOG4105N5T Radical SAM Protein BAY22_16650 ENOG4105CBC glutamate synthase BAY22_16655 ENOG4105BZ8 glutamate synthase BAY22_16665 ENOG4105KB2 stringent starvation protein b BAY22_16670 ENOG4107MKT Stringent starvation protein a BAY22_16690 ENOG4105D6Z AFG1 family ATPase BAY22_16695 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BAY22_16700 ENOG4105C0H protease BAY22_16705 ENOG4108RS6 transposase BAY22_16710 ENOG4105C0H protease BAY22_16720 ENOG4105VFK BolA family BAY22_16725 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BAY22_16730 ENOG4105E3I toluene tolerance BAY22_16735 ENOG4107PE3 Mammalian cell entry related domain protein BAY22_16740 ENOG4105CY3 ABC transporter, permease BAY22_16745 ENOG4105DHJ ABC, transporter BAY22_16750 ENOG4105FEU K -dependent Na -Ca exchanger BAY22_16755 ENOG4105C2X Arabinose 5-phosphate isomerase BAY22_16760 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BAY22_16765 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BAY22_16770 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BAY22_16775 ENOG4108IUZ ABC transporter BAY22_16780 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAY22_16790 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BAY22_16800 ENOG41080Z8 PHOSPHOCARRIER protein BAY22_16815 ENOG4105KME endoribonuclease L-psp BAY22_16835 ENOG4105D4X repressor BAY22_16840 ENOG4105C5Y PTS System BAY22_16845 ENOG4105CG3 alpha amylase, catalytic region BAY22_16850 ENOG4105NXH GreA GreB family elongation factor BAY22_16855 ENOG4108XVM Cytochrome b(562) BAY22_16865 ENOG4105CMS peptidase U62, modulator of DNA gyrase BAY22_16875 ENOG4105UNR (Barnase) inhibitor BAY22_16890 ENOG4105C26 Dehydrogenase BAY22_16910 ENOG4105CR8 Transcriptional regulator BAY22_16965 ENOG4105D1U peptidase U62 modulator of DNA gyrase BAY22_16980 ENOG4105C03 ribonuclease BAY22_16990 ENOG4105VQ7 Rod shape-determining protein MreD BAY22_16995 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAY22_17000 ENOG4105DFF Rod shape-determining protein mreb BAY22_17005 ENOG41062P1 Diguanylate cyclase phosphodiesterase BAY22_17010 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BAY22_17015 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) BAY22_17030 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BAY22_17035 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAY22_17040 ENOG4105RG0 Membrane BAY22_17045 ENOG4108IA2 Sodium pantothenate symporter BAY22_17055 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAY22_17060 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BAY22_17080 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BAY22_17095 ENOG4108XTF Outer Membrane Lipoprotein BAY22_17105 ENOG4105VEQ Cold shock protein BAY22_17110 ENOG4105VEQ Cold shock protein BAY22_17115 ENOG4108RS6 transposase BAY22_17135 ENOG4105C2X Arabinose 5-phosphate isomerase BAY22_17140 ENOG4105EF1 ribulokinase BAY22_17150 ENOG4105CNN ABC, transporter BAY22_17155 ENOG4105C2J ABC transporter BAY22_17165 ENOG4105D1S lipid A biosynthesis BAY22_17175 ENOG4105EEQ Na H antiporter BAY22_17180 ENOG4105C7N Xanthine uracil vitamin C permease BAY22_17195 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAY22_17205 ENOG4105GVF (ABC) transporter BAY22_17215 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BAY22_17225 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BAY22_17230 ENOG4105W4W Transcriptional regulator BAY22_17235 ENOG4107TYG Oxidoreductase domain-containing protein BAY22_17250 ENOG4105CNA YD repeat protein BAY22_17260 ENOG4105CS6 Rhs element vgr protein BAY22_17285 ENOG4105CNA YD repeat protein BAY22_17300 ENOG4105CS6 Rhs element vgr protein BAY22_17335 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAY22_17410 ENOG4108WC9 type VI secretion system effector, hcp1 family BAY22_17420 ENOG4107W52 maltose operon periplasmic protein BAY22_17440 ENOG4107FKK extracellular solute-binding protein family 1 BAY22_17445 ENOG4105D56 permease protein BAY22_17450 ENOG4105EG2 ABC transporter, permease BAY22_17465 ENOG4105CFH Aspartokinase BAY22_17480 ENOG4105C3R Methionine synthase BAY22_17485 ENOG41069M3 Transcriptional regulator BAY22_17490 ENOG41069M3 Transcriptional regulator BAY22_17500 ENOG4108I9X Isocitrate lyase BAY22_17505 ENOG4107QP3 malate synthase g BAY22_17565 ENOG4105C12 Phosphoribosylglycinamide synthetase BAY22_17570 ENOG4108T8B Protein of unknown function (DUF1481) BAY22_17580 ENOG4105R2J Conserved Protein BAY22_17585 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BAY22_17610 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BAY22_17620 ENOG4105D06 uba thif-type nad fad binding protein BAY22_17630 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BAY22_17635 ENOG4105D41 biosynthesis protein thiH BAY22_17645 ENOG4108RS6 transposase BAY22_17680 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAY22_17685 ENOG4105PM1 preprotein translocase subunit SecE BAY22_17735 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BAY22_17740 ENOG4105D4A Cell wall formation (By similarity) BAY22_17770 ENOG4108RR8 protoporphyrinogen oxidase BAY22_17775 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BAY22_17780 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAY22_17785 ENOG4108RS6 transposase BAY22_17790 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAY22_17810 ENOG4107QK7 reductase BAY22_17820 ENOG4105MDZ Transcriptional activator rfaH BAY22_17825 ENOG4105D52 delta-aminolevulinic acid dehydratase BAY22_17850 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAY22_17860 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BAY22_17870 ENOG4105JC1 sterol-binding domain protein BAY22_17880 ENOG4105CGY Dna recombination protein BAY22_17885 ENOG4108KF1 Membrane BAY22_17900 ENOG4108I5U Uridine phosphorylase BAY22_17905 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BAY22_17915 ENOG4105DZ2 Transcriptional regulator BAY22_17920 ENOG4105EMK carboxylate amino acid amine transporter BAY22_17925 ENOG4105RK9 auxin efflux carrier BAY22_17930 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BAY22_17990 ENOG4108IV0 ABC, transporter BAY22_17995 ENOG4105C0Z ABC transporter BAY22_18000 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BAY22_18005 ENOG4105C32 Amino acid ABC transporter (Permease) BAY22_18010 ENOG4105CP9 extracellular ligand-binding receptor BAY22_18015 ENOG4105U59 -acetyltransferase BAY22_18020 ENOG4108RS6 transposase BAY22_18030 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAY22_18040 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAY22_18040 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAY22_18050 ENOG4106H78 methyltransferase BAY22_18055 ENOG4105MG3 Membrane BAY22_18070 ENOG4107FS9 Membrane BAY22_18085 ENOG4105EX9 Membrane BAY22_18090 ENOG4108W1V Lipoprotein BAY22_18095 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAY22_18105 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BAY22_18115 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BAY22_18125 ENOG4105DQF Hydrolase BAY22_18130 ENOG4108EUD Lysophospholipase BAY22_18140 ENOG4105CCF Lysine exporter protein (Lyse ygga) BAY22_18145 ENOG4105C9U ATP-dependent DNA helicase RecQ BAY22_18150 ENOG4105HDD phospholipase BAY22_18155 ENOG4108VUY thioesterase Superfamily protein BAY22_18160 ENOG4105FR1 rard protein BAY22_18165 ENOG4107QUT magnesium and cobalt transport protein CorA BAY22_18175 ENOG4105EQN UPF0261 protein BAY22_18185 ENOG4105C4R Atp-dependent dna helicase BAY22_18190 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BAY22_18195 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAY22_18200 ENOG4105CT0 Protein of unknown function, DUF484 BAY22_18210 ENOG4105S7Z (LipO)protein BAY22_18220 ENOG4107T0K Adenylate cyclase BAY22_18235 ENOG41076E6 Uroporphyrinogen-III Synthase BAY22_18240 ENOG4105ECF c-methyltransferase BAY22_18245 ENOG410601J HemY protein BAY22_18250 ENOG4108RS6 transposase BAY22_18310 ENOG4105DP9 ABC transporter BAY22_18315 ENOG4106SMU thiamine transporter membrane protein BAY22_18325 ENOG4108KF1 Membrane BAY22_18330 ENOG4105CQ2 DNA polymerase BAY22_18390 ENOG4105CS6 Rhs element vgr protein BAY22_18395 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAY22_18440 ENOG4105D3G Pseudouridine synthase BAY22_18445 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) BAY22_18455 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BAY22_18460 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BAY22_18490 ENOG4108RS6 transposase BAY22_18495 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BAY22_18505 ENOG4105DWK Membrane BAY22_18510 ENOG4105N14 lysine exporter protein LysE YggA BAY22_18515 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BAY22_18520 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAY22_18530 ENOG4108RS6 transposase BAY22_18545 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BAY22_18560 ENOG4105DTN riboflavin biosynthesis protein ribF BAY22_18575 ENOG41063Z6 transcriptional regulator, lysR family BAY22_18595 ENOG4106HK8 GPR1 FUN34 yaaH family protein BAY22_18610 ENOG4108RIR Molybdenum cofactor biosynthesis protein BAY22_18640 ENOG41065U4 response regulator BAY22_18645 ENOG4108RH0 Crea protein BAY22_18650 ENOG4105UEI Transcriptional Regulator AraC Family BAY22_18665 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BAY22_18670 ENOG4107SC1 transglycosylase BAY22_18685 ENOG4108KHX Diguanylate cyclase BAY22_18690 ENOG41090EK ompa motb domain protein BAY22_18705 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BAY22_18710 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAY22_18715 ENOG4105EAC phosphoserine phosphatase BAY22_18720 ENOG41062Z9 Membrane BAY22_18745 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BAY22_18750 ENOG4105D9N nucleoside BAY22_18755 ENOG4105EYA deoxyribonuclease BAY22_18760 ENOG4108NRW Phospholipase, patatin family BAY22_18770 ENOG4105K3G Periplasmic Protein BAY22_18780 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BAY22_18785 ENOG4108WPU DNA polymerase III subunit psi BAY22_18800 ENOG4105YBH Protein of unknown function (DUF1435) BAY22_18805 ENOG4105BZU Histidine kinase BAY22_18830 ENOG4105BZS acriflavin resistance protein BAY22_18835 ENOG410624X efflux transporter, rnd family, mfp subunit BAY22_18855 ENOG4105DKP glycosyl transferase, family 9 BAY22_18905 ENOG4105RI1 glycoprotein receptor BAY22_18910 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAY22_18915 ENOG4105DM4 PTS System BAY22_18920 ENOG4108YRF PTS System BAY22_18925 ENOG4108XCZ PTS System BAY22_18930 ENOG4106R3P AraC family transcriptional regulator BAY22_18940 ENOG4108M3P Membrane BAY22_19010 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 BAY22_19030 ENOG4105WSB biofilm stress and motility protein A BAY22_19035 ENOG4105CSU acyl-Coa dehydrogenase BAY22_19040 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAY22_19045 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAY22_19065 ENOG4105EPW hflc protein BAY22_19070 ENOG4107QJR hflk protein BAY22_19075 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAY22_19095 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAY22_19100 ENOG4105K8N protein family UPF0079, ATPase BAY22_19105 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BAY22_19110 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAY22_19120 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) BAY22_19140 ENOG4105EGS Mechanosensitive ion channel BAY22_19170 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BAY22_19180 ENOG4108RS6 transposase BAY22_19185 ENOG4105KPY Small multidrug resistance protein BAY22_19195 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAY22_19200 ENOG4108ZVF (LipO)protein BAY22_19240 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BAY22_19245 ENOG4108RC0 Electron transport protein BAY22_19250 ENOG4105BZ8 glutamate synthase BAY22_19255 ENOG4108SIC Transcriptional regulator BAY22_19325 ENOG4105C0A alcohol dehydrogenase BAY22_19335 ENOG4108UUM single-stranded DNA-binding protein BAY22_19340 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAY22_19345 ENOG4105MSB protein, conserved in bacteria BAY22_19350 ENOG4105CGF Aromatic amino acid aminotransferase BAY22_19355 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAY22_19360 ENOG4105CDU Replicative dna helicase BAY22_19365 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BAY22_19370 ENOG4105P4Z Phage shock protein G BAY22_19375 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAY22_19380 ENOG4105MYN Zinc uptake regulation protein BAY22_19390 ENOG41080IJ Diacylglycerol kinase BAY22_19435 ENOG4108S1B Periplasmic chaperone protein BAY22_19450 ENOG4108RS6 transposase BAY22_19505 ENOG4105DAX Pfam:DUF2983 BAY22_19525 ENOG4105D4P Coproporphyrinogen iii oxidase BAY22_19530 ENOG41090JE Utilization Protein BAY22_19540 ENOG4107ENK receptor BAY22_19545 ENOG4106QJH hemin transport protein BAY22_19550 ENOG4107R4I Periplasmic binding protein BAY22_19555 ENOG4105EHG Permease protein BAY22_19570 ENOG4105C44 Serine transporter BAY22_19575 ENOG4105EQ2 LysR family Transcriptional regulator BAY22_19580 ENOG4105KSU Redox protein BAY22_19585 ENOG41066VF YeeE YedE family protein BAY22_19590 ENOG4108IUF type iii secretion BAY22_19595 ENOG4108TN6 type iii secretion BAY22_19600 ENOG41083GP type iii secretion BAY22_19605 ENOG4108HHI Type III secretion system protein BAY22_19610 ENOG41063Q7 Type III secretion system protein BAY22_19625 ENOG4108JIR Flagellum-specific ATP synthase BAY22_19685 ENOG4105BZU Histidine kinase BAY22_19690 ENOG4105WH1 Two component transcriptional regulator luxr family BAY22_19695 ENOG4105CK2 sodium dicarboxylate symporter BAY22_19705 ENOG41062QD Membrane BAY22_19730 ENOG4108Z0R Transferase BAY22_19745 ENOG4108WI1 Dna topoisomerase BAY22_19755 ENOG4105C79 DNA protecting protein DprA BAY22_19775 ENOG4105C1A potassium transporter peripheral membrane BAY22_19785 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BAY22_19790 ENOG4105W1Y Transcriptional regulator BAY22_19805 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BAY22_19820 ENOG41067V7 50S ribosomal protein L36 BAY22_19825 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAY22_19835 ENOG4105VPB 50S ribosomal protein L30 BAY22_19880 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BAY22_19890 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BAY22_19895 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BAY22_19905 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BAY22_19945 ENOG4108RS6 transposase BAY22_19960 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BAY22_19985 ENOG4105WWK YheO domain protein BAY22_19990 ENOG4108V1T peptidylprolyl cis-trans isomerase BAY22_20000 ENOG4108YZY peptidylprolyl cis-trans isomerase BAY22_20005 ENOG4105VKU nucleicacid-binding protein BAY22_20025 ENOG4105K64 Glycosyl transferase, family 2 BAY22_20035 ENOG4105E2B Taurine dioxygenase BAY22_20040 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAY22_20050 ENOG4106FTQ Taurine ABC transporter, periplasmic BAY22_20060 ENOG4105DNZ Alpha Beta Hydrolase BAY22_20070 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BAY22_20080 ENOG4108UKZ OsmC family BAY22_20090 ENOG410613R integral membrane protein, YccS YhfK family BAY22_20120 ENOG4105D7A ATP-binding protein BAY22_20125 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BAY22_20130 ENOG4105F8D glycoside hydrolase family 4 BAY22_20135 ENOG41060NJ transcriptional regulator BAY22_20150 ENOG4105DZC cytosine deaminase BAY22_20155 ENOG4107QZF nitrite reductase NADPH large subunit BAY22_20160 ENOG4105WZK nitrite reductase NADPH small subunit BAY22_20165 ENOG4107V9H nitrite transporter BAY22_20175 ENOG4105C31 Tryptophanyl-tRNA synthetase BAY22_20180 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BAY22_20185 ENOG4105DJV ribulose-phosphate 3-epimerase BAY22_20210 ENOG4105E4G Type IV pilus BAY22_20240 ENOG4108JQC penicillin-binding protein 1A BAY22_20245 ENOG4107RK2 ADP-ribose diphosphatase NudE BAY22_20255 ENOG4105DQY intracellular growth attenuator BAY22_20260 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BAY22_20265 ENOG4105VEJ Heat shock protein BAY22_20280 ENOG4105E0F Histidine kinase BAY22_20285 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAY22_20290 ENOG4108RRZ Transcription elongation factor GreB BAY22_20295 ENOG4105BZM domain protein BAY22_20305 ENOG4105XFK Ferrous iron transport protein A BAY22_20310 ENOG4105CE1 Ferrous iron transport protein b BAY22_20320 ENOG4105RID UPF0379 protein yhcN BAY22_20330 ENOG4105MJ2 Competence protein BAY22_20340 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BAY22_20345 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BAY22_20350 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BAY22_20360 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BAY22_20370 ENOG4105E98 transcriptional regulator DeoR family BAY22_20380 ENOG4105DQ6 Transposase BAY22_20385 ENOG4105SYT Methylenetetrahydrofolate reductase BAY22_20390 ENOG4105CFH Aspartokinase BAY22_20410 ENOG4108Z12 YiaAB two helix domain-containing protein BAY22_20420 ENOG4105C25 Primosomal protein n' BAY22_20430 ENOG4105ETE Transcriptional regulator (LacI family BAY22_20435 ENOG41063M6 Cell Division Protein BAY22_20450 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAY22_20475 ENOG4108MBX Secretion Protein BAY22_20500 ENOG4108RS6 transposase BAY22_20515 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BAY22_20535 ENOG4108VTS Membrane BAY22_20540 ENOG4105EBK exported protein BAY22_20550 ENOG4107F9Y LysR family transcriptional regulator BAY22_20560 ENOG4105JSC dimethylmenaquinone methyltransferase BAY22_20565 ENOG4107QPK )-transporter BAY22_20575 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BAY22_20595 ENOG4105FMW periplasmic BAY22_20600 ENOG4105E3W Two component transcriptional regulator (Winged helix family BAY22_20605 ENOG4105E0F Histidine kinase BAY22_20610 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAY22_20615 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAY22_20620 ENOG4105D7W serine acetyltransferase BAY22_20640 ENOG4105VW4 glutaredoxin 3 BAY22_20645 ENOG4107YZP Rhodanese domain protein BAY22_20655 ENOG41063SB peptidase BAY22_20670 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAY22_20680 ENOG4105XA0 heptosyltransferase ii BAY22_20685 ENOG4105D16 lipopolysaccharide heptosyltransferase i BAY22_20690 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BAY22_20710 ENOG4105W0E 50S ribosomal protein L33 BAY22_20725 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAY22_20750 ENOG4105DSJ YicC domain protein BAY22_20755 ENOG4105EN6 Membrane BAY22_20760 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) BAY22_20775 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAY22_20780 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BAY22_20785 ENOG4105CB5 ATP-dependent DNA helicase recG BAY22_20790 ENOG4105D6U Sodium Glutamate Symporter BAY22_20795 ENOG4105C2W permease BAY22_20800 ENOG4105JV1 AsmA family BAY22_20805 ENOG4105SUU thioesterase domain BAY22_20825 ENOG4107S2Z UPF0761 membrane protein BAY22_20830 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BAY22_20845 ENOG4105C5F glutamine synthetase BAY22_20850 ENOG4105CUX Signal transduction histidine kinase BAY22_20855 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAY22_20875 ENOG4108RS6 transposase BAY22_20880 ENOG4105C2M dna polymerase I BAY22_20885 ENOG4108Z33 Thiol disulfide Interchange Protein BAY22_20890 ENOG4105E27 serine threonine protein kinase BAY22_20895 ENOG4105PC1 Conserved Protein BAY22_20905 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BAY22_20940 ENOG4107EJG GntR family transcriptional regulator BAY22_20945 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAY22_20955 ENOG4108RVA ribokinase BAY22_20985 ENOG4108VVK transcriptional Regulator, AsnC BAY22_20990 ENOG4105QTB Flavodoxin BAY22_21005 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BAY22_21015 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BAY22_21055 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BAY22_21060 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BAY22_21065 ENOG4105C8U phosphate abc transporter BAY22_21070 ENOG4105E2Z phosphate ABC transporter (Permease BAY22_21090 ENOG4106PMH Extracellular solute-binding protein family 3 BAY22_21095 ENOG4105EAD ABC transporter BAY22_21100 ENOG4105DRP amino acid AbC transporter BAY22_21105 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BAY22_21110 ENOG4105C7N Xanthine uracil vitamin C permease BAY22_21135 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAY22_21145 ENOG4105VG0 50S ribosomal protein l34 BAY22_21155 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAY22_21165 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BAY22_21170 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAY22_21175 ENOG410667J hydrolase BAY22_21180 ENOG4105DQ6 Transposase BAY22_21195 ENOG4105C7B Threonine dehydratase BAY22_21200 ENOG4105D99 atp gtp-binding protein BAY22_21205 ENOG4105D99 atp gtp-binding protein BAY22_21210 ENOG4105R2A (LipO)protein BAY22_21230 ENOG4105JKW Valine--pyruvate aminotransferase BAY22_21390 ENOG4105CMM transposase BAY22_21400 ENOG4105E5H Transposase BAY22_21405 ENOG4105CMM transposase BAY22_21430 ENOG4106CQM replication BAY22_21440 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) BAY22_21490 ENOG4105D13 transposase BAY22_21495 ENOG4108C33 Resolvase BAY22_21515 ENOG4105CMM transposase BAY22_21550 ENOG4105CMM transposase BAY22_21580 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB BAY22_21585 ENOG4105EZN Cobyrinic acid ac-diamide synthase BAY22_21710 ENOG4106PHM regulatory protein BAY22_21725 ENOG4105EQR Transposase IS116 IS110 IS902 BAY22_21790 ENOG4106RMF ParB family BAY22_21815 ENOG41073YN Protein of unknown function (DUF1380) BAY22_21835 ENOG4105FEQ ParB domain protein nuclease BAY22_21850 ENOG4106J5W DNA polymerase III (alpha subunit) BAY22_21880 ENOG4105C2M dna polymerase I BAY22_21890 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BAY22_21935 ENOG4106JVB Replication Protein BAY22_21950 ENOG4105D2X ABC transporter substrate-binding protein BAY22_21985 ENOG4108RS6 transposase BAY22_22035 ENOG4105CB5 ATP-dependent DNA helicase recG BAY22_22040 ENOG4105FA0 parb-like partition protein BAY22_22045 ENOG4105FA0 parb-like partition protein BAY22_22140 ENOG4108NYK Tape measure protein BAY22_22175 ENOG4108X9F tail fiber protein BAY22_22175 ENOG4108X9F tail fiber protein BAY22_22185 ENOG4105UZW Tail fiber assembly protein BAY22_22200 ENOG4106J5W DNA polymerase III (alpha subunit) BAY22_22235 ENOG4108D1K outer membrane usher protein BAY22_22240 ENOG4108UIF Chaperone BAY22_22250 ENOG4105XUP Phage derived protein Gp49-like (DUF891)