locus-tag	class	description
BAY22_00030	COG0437	4 iron, 4 sulfur cluster binding
BAY22_00035	COG2864	formate dehydrogenase
BAY22_00050	COG3276	selenocysteine insertion sequence binding
BAY22_00085	COG2801	Transposase and inactivated derivatives
BAY22_00095	COG2423	ornithine cyclodeaminase activity
BAY22_00100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BAY22_00105	COG0823	Involved in the tonB-independent uptake of proteins
BAY22_00110	COG0823	Involved in the tonB-independent uptake of proteins
BAY22_00115	COG5645	(Lipo)protein
BAY22_00135	COG3977	Valine--pyruvate aminotransferase
BAY22_00145	COG0366	Alpha amylase catalytic
BAY22_00160	COG2885	chlorophyll binding
BAY22_00170	COG2818	Glycosylase
BAY22_00190	COG2213	PTS system mannitol-specific
BAY22_00190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_00200	COG3722	fumarate hydratase activity
BAY22_00225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BAY22_00235	COG0243	molybdopterin cofactor binding
BAY22_00235	COG3383	formate dehydrogenase (NAD+) activity
BAY22_00240	COG0243	molybdopterin cofactor binding
BAY22_00240	COG3383	formate dehydrogenase (NAD+) activity
BAY22_00245	COG0437	4 iron, 4 sulfur cluster binding
BAY22_00250	COG2864	formate dehydrogenase
BAY22_00265	COG3276	selenocysteine insertion sequence binding
BAY22_00270	COG3276	selenocysteine insertion sequence binding
BAY22_00305	COG2801	Transposase and inactivated derivatives
BAY22_00320	COG3274	enterobacterial common antigen metabolic process
BAY22_00330	COG3188	usher protein
BAY22_00335	COG3188	usher protein
BAY22_00340	COG3121	Chaperone
BAY22_00350	COG1070	Carbohydrate kinase
BAY22_00360	COG4213	ABC transporter substrate-binding protein
BAY22_00370	COG4214	carbohydrate transport
BAY22_00375	COG2207	Transcriptional regulator
BAY22_00375	COG1609	Transcriptional regulator
BAY22_00380	COG0582	viral genome integration into host DNA
BAY22_00420	COG4604	ABC transporter, ATP-binding protein
BAY22_00425	COG4605	iron ion homeostasis
BAY22_00435	COG4607	ABC-type enterochelin transport system periplasmic component
BAY22_00450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BAY22_00465	COG2986	histidine ammonia-lyase
BAY22_00480	COG2194	sulfuric ester hydrolase activity
BAY22_00485	COG2197	response regulator
BAY22_00490	COG3851	Histidine kinase
BAY22_00510	COG2271	Major facilitator Superfamily
BAY22_00525	COG2831	hemolysin activation secretion protein
BAY22_00535	COG0747	negative chemotaxis
BAY22_00545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAY22_00550	COG0444	Belongs to the ABC transporter superfamily
BAY22_00555	COG4608	Belongs to the ABC transporter superfamily
BAY22_00560	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BAY22_00565	COG2200	EAL domain
BAY22_00565	COG2199	diguanylate cyclase activity
BAY22_00570	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BAY22_00590	COG0612	Peptidase, M16
BAY22_00595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAY22_00600	COG1942	4-Oxalocrotonate Tautomerase
BAY22_00605	COG2200	EAL domain
BAY22_00610	COG2982	Protein involved in outer membrane biogenesis
BAY22_00615	COG2134	cdp-diacylglycerol pyrophosphatase
BAY22_00620	COG1295	ribonuclease BN
BAY22_00645	COG1929	Belongs to the glycerate kinase type-1 family
BAY22_00650	COG2610	gluconate transmembrane transporter activity
BAY22_00655	COG3835	regulator
BAY22_00660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BAY22_00665	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BAY22_00670	COG0339	signal peptide processing
BAY22_00690	COG0589	response to stress
BAY22_00700	COG1943	Transposase
BAY22_00705	COG0306	phosphate transporter
BAY22_00725	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_00730	COG1879	ABC-type sugar transport system periplasmic component
BAY22_00740	COG0191	fructose-bisphosphate aldolase activity
BAY22_00750	COG0745	RESPONSE REGULATOR receiver
BAY22_00760	COG1741	Belongs to the pirin family
BAY22_00765	COG1609	Transcriptional regulator
BAY22_00770	COG2610	gluconate transmembrane transporter activity
BAY22_00775	COG3265	gluconokinase activity
BAY22_00795	COG2095	MarC family integral membrane protein
BAY22_00800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BAY22_00830	COG3275	phosphorelay sensor kinase activity
BAY22_00845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BAY22_00855	COG0058	SHG alpha-glucan phosphorylase activity
BAY22_00860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BAY22_00880	COG2801	Transposase and inactivated derivatives
BAY22_00910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BAY22_00930	COG1629	transport
BAY22_00955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BAY22_00960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BAY22_00960	COG0678	peroxiredoxin activity
BAY22_01035	COG1879	ABC-type sugar transport system periplasmic component
BAY22_01040	COG1129	ABC transporter
BAY22_01045	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_01050	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_01060	COG3085	chromosome segregation
BAY22_01075	COG3978	acetolactate synthase activity
BAY22_01080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BAY22_01125	COG0583	DNA-binding transcription factor activity
BAY22_01165	COG3121	Chaperone
BAY22_01180	COG3121	Chaperone
BAY22_01195	COG3328	transposase activity
BAY22_01205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BAY22_01235	COG3118	belongs to the thioredoxin family
BAY22_01240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BAY22_01245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BAY22_01250	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BAY22_01255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BAY22_01260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BAY22_01265	COG1088	dTDP-glucose 4,6-dehydratase activity
BAY22_01270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BAY22_01275	COG0456	acetyltransferase
BAY22_01280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BAY22_01285	COG2244	polysaccharide biosynthetic process
BAY22_01305	COG1113	amino acid transport
BAY22_01320	COG2814	Major facilitator Superfamily
BAY22_01335	COG0473	3-isopropylmalate dehydrogenase activity
BAY22_01345	COG1943	Transposase
BAY22_01360	COG1022	Amp-dependent synthetase and ligase
BAY22_01370	COG0028	Belongs to the TPP enzyme family
BAY22_01380	COG1943	Transposase
BAY22_01390	COG1609	Transcriptional regulator
BAY22_01410	COG3116	cell division
BAY22_01415	COG0768	penicillin binding
BAY22_01420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BAY22_01425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BAY22_01440	COG0772	Belongs to the SEDS family
BAY22_01460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BAY22_01465	COG0849	cell division
BAY22_01470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BAY22_01495	COG0494	nUDIX hydrolase
BAY22_01510	COG0435	Glutathione S-transferase
BAY22_01515	COG2259	Doxx family
BAY22_01525	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BAY22_01530	COG4575	ribosome binding
BAY22_01550	COG0586	Pfam SNARE associated Golgi protein
BAY22_01565	COG2271	Major facilitator Superfamily
BAY22_01580	COG0246	Mannitol dehydrogenase
BAY22_01585	COG2721	sulfolactate sulfo-lyase activity
BAY22_01595	COG1943	Transposase
BAY22_01605	COG0673	inositol 2-dehydrogenase activity
BAY22_01610	COG1451	nucleotide metabolic process
BAY22_01625	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAY22_01625	COG1902	pentaerythritol trinitrate reductase activity
BAY22_01630	COG3247	response to pH
BAY22_01650	COG4245	von Willebrand factor, type A
BAY22_01665	COG4245	von Willebrand factor, type A
BAY22_01670	COG2831	hemolysin activation secretion protein
BAY22_01685	COG3210	domain, Protein
BAY22_01690	COG3210	domain, Protein
BAY22_01700	COG3210	domain, Protein
BAY22_01705	COG3210	domain, Protein
BAY22_01725	COG3842	ATPase activity
BAY22_01730	COG3459	Glycosyltransferase 36 associated
BAY22_01735	COG1609	Transcriptional regulator
BAY22_01740	COG1653	transport
BAY22_01750	COG0395	ABC-type sugar transport system, permease component
BAY22_01770	COG1289	transmembrane transporter activity
BAY22_01815	COG0251	oxidation-reduction process
BAY22_01905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BAY22_01910	COG0358	DNA primase activity
BAY22_01930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BAY22_01945	COG4991	sh3 domain protein
BAY22_01950	COG3025	triphosphatase activity
BAY22_01965	COG0531	amino acid
BAY22_01980	COG3384	dioxygenase
BAY22_01985	COG0754	glutathionylspermidine amidase activity
BAY22_02000	COG1538	Outer membrane efflux protein
BAY22_02005	COG0494	nUDIX hydrolase
BAY22_02010	COG3151	Protein conserved in bacteria
BAY22_02015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BAY22_02020	COG3150	esterase
BAY22_02025	COG0187	DNA topoisomerase II activity
BAY22_02030	COG0583	DNA-binding transcription factor activity
BAY22_02035	COG2249	NAD(P)H dehydrogenase (quinone) activity
BAY22_02040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BAY22_02045	COG0204	Acyl-transferase
BAY22_02050	COG2132	Multicopper oxidase
BAY22_02060	COG0656	L-ascorbic acid biosynthetic process
BAY22_02070	COG1979	alcohol dehydrogenase
BAY22_02075	COG2207	Transcriptional regulator
BAY22_02085	COG0626	cystathionine gamma-synthase activity
BAY22_02090	COG0811	peptide transport
BAY22_02095	COG0848	biopolymer transport protein
BAY22_02145	COG4964	Belongs to the GSP D family
BAY22_02150	COG4964	Belongs to the GSP D family
BAY22_02165	COG1943	Transposase
BAY22_02170	COG1943	Transposase
BAY22_02190	COG4592	Periplasmic binding protein
BAY22_02210	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BAY22_02215	COG1684	flagellar biosynthetic protein fliR
BAY22_02220	COG1987	bacterial-type flagellum assembly
BAY22_02240	COG2204	response regulator
BAY22_02285	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BAY22_02290	COG1815	bacterial-type flagellum-dependent cell motility
BAY22_02295	COG1558	bacterial-type flagellum-dependent cell motility
BAY22_02300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BAY22_02305	COG1749	Flagellar hook protein flgE
BAY22_02315	COG1943	Transposase
BAY22_02325	COG4786	Flagellar basal body rod
BAY22_02330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BAY22_02335	COG1706	bacterial-type flagellum-dependent cell motility
BAY22_02345	COG1256	bacterial-type flagellum assembly
BAY22_02365	COG3710	Transcriptional regulator
BAY22_02385	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BAY22_02410	COG1191	sigma factor activity
BAY22_02415	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BAY22_02475	COG0471	metal ion transport
BAY22_02490	COG3209	COG3209 Rhs family protein
BAY22_02500	COG3501	Rhs element vgr protein
BAY22_02515	COG2610	gluconate transmembrane transporter activity
BAY22_02565	COG3433	isochorismatase activity
BAY22_02565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BAY22_02565	COG2226	methyltransferase
BAY22_02570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BAY22_02575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BAY22_02575	COG3433	isochorismatase activity
BAY22_02575	COG2226	methyltransferase
BAY22_02635	COG0667	Aldo Keto reductase
BAY22_02665	COG1609	Transcriptional regulator
BAY22_02670	COG0019	diaminopimelate decarboxylase activity
BAY22_02675	COG0583	DNA-binding transcription factor activity
BAY22_02680	COG2814	Major facilitator Superfamily
BAY22_02685	COG0583	DNA-binding transcription factor activity
BAY22_02700	COG0840	transmembrane signaling receptor activity
BAY22_02790	COG0288	reversible hydration of carbon dioxide
BAY22_02830	COG1943	Transposase
BAY22_02835	COG3119	arylsulfatase activity
BAY22_02840	COG1349	DNA-binding transcription factor activity
BAY22_02850	COG2222	sugar isomerase
BAY22_02855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAY22_02860	COG3715	PTS system
BAY22_02865	COG3716	PTS system mannose fructose sorbose family IID component
BAY22_02870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_02880	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_02890	COG0641	radical SAM
BAY22_02895	COG3119	arylsulfatase activity
BAY22_02905	COG0191	fructose-bisphosphate aldolase activity
BAY22_02925	COG2271	Major facilitator Superfamily
BAY22_02945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAY22_02945	COG1263	PTS System
BAY22_02950	COG1874	Beta-galactosidase
BAY22_02955	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BAY22_02960	COG3833	ABC-type maltose transport systems, permease component
BAY22_02965	COG1175	transmembrane transport
BAY22_02970	COG2182	Extracellular solute-binding protein
BAY22_02980	COG1129	ABC transporter
BAY22_02985	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_02990	COG1879	ABC-type sugar transport system periplasmic component
BAY22_03000	COG0791	NLP P60 protein
BAY22_03005	COG1695	Transcriptional regulator
BAY22_03100	COG2944	sequence-specific DNA binding
BAY22_03130	COG0582	viral genome integration into host DNA
BAY22_03150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BAY22_03155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BAY22_03160	COG4974	Belongs to the 'phage' integrase family
BAY22_03165	COG0716	FMN binding
BAY22_03170	COG4452	Inner membrane protein CreD
BAY22_03175	COG2205	protein histidine kinase activity
BAY22_03180	COG0745	RESPONSE REGULATOR receiver
BAY22_03190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BAY22_03205	COG1272	protein, Hemolysin III
BAY22_03215	COG5295	Hep Hag repeat protein
BAY22_03245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BAY22_03250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BAY22_03255	COG0006	proline dipeptidase activity
BAY22_03275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BAY22_03280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BAY22_03285	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BAY22_03310	COG0191	fructose-bisphosphate aldolase activity
BAY22_03335	COG1943	Transposase
BAY22_03340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BAY22_03345	COG0501	Belongs to the peptidase M48B family
BAY22_03355	COG1166	arginine decarboxylase activity
BAY22_03365	COG3091	SprT-like family
BAY22_03370	COG2356	endonuclease I
BAY22_03375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BAY22_03380	COG0189	ligase activity
BAY22_03395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BAY22_03405	COG2805	Type II/IV secretion system protein
BAY22_03410	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BAY22_03415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BAY22_03420	COG0762	integral membrane protein
BAY22_03430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BAY22_03435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BAY22_03440	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BAY22_03440	COG3064	Membrane
BAY22_03440	COG1073	alpha beta
BAY22_03455	COG2066	Belongs to the glutaminase family
BAY22_03460	COG3171	Protein conserved in bacteria
BAY22_03470	COG1194	a g-specific adenine glycosylase
BAY22_03490	COG4774	siderophore transport
BAY22_03495	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_03500	COG1129	ABC transporter
BAY22_03505	COG1879	ABC-type sugar transport system periplasmic component
BAY22_03510	COG1982	Orn Lys Arg decarboxylase major
BAY22_03530	COG1662	PFAM IS1 transposase
BAY22_03645	COG3916	Acyl-homoserine-lactone synthase
BAY22_03650	COG2771	luxR family
BAY22_03705	COG2211	Major facilitator Superfamily
BAY22_03715	COG2801	Transposase and inactivated derivatives
BAY22_03720	COG3300	MHYT domain
BAY22_03720	COG5001	Diguanylate cyclase
BAY22_03730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAY22_03770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BAY22_03775	COG2195	Cleaves the N-terminal amino acid of tripeptides
BAY22_03780	COG4771	TonB-dependent receptor
BAY22_03815	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BAY22_03825	COG1074	ATP-dependent DNA helicase activity
BAY22_03830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BAY22_03840	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAY22_03855	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BAY22_03860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BAY22_03865	COG2166	iron-sulfur cluster assembly
BAY22_03870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BAY22_03875	COG0583	DNA-binding transcription factor activity
BAY22_03880	COG2363	Small membrane protein
BAY22_03890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BAY22_03895	COG1611	Belongs to the LOG family
BAY22_03910	COG1943	Transposase
BAY22_03915	COG3098	single-species biofilm formation
BAY22_03920	COG0564	pseudouridine synthase activity
BAY22_03945	COG0024	Methionine aminopeptidase
BAY22_03975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BAY22_03980	COG0575	Belongs to the CDS family
BAY22_03985	COG0750	zinc metalloprotease
BAY22_03995	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BAY22_04015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BAY22_04025	COG0587	DNA-directed DNA polymerase activity
BAY22_04035	COG0346	lactoylglutathione lyase activity
BAY22_04040	COG0037	tRNA processing
BAY22_04050	COG4568	rho-dependent transcription termination
BAY22_04060	COG4681	YaeQ
BAY22_04070	COG3015	lipoprotein NlpE involved in copper resistance
BAY22_04080	COG1720	tRNA m6t6A37 methyltransferase activity
BAY22_04090	COG1464	Belongs to the NlpA lipoprotein family
BAY22_04095	COG2011	ABC-type metal ion transport system permease component
BAY22_04105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BAY22_04135	COG0656	L-ascorbic acid biosynthetic process
BAY22_04150	COG1388	LysM domain
BAY22_04150	COG0741	lytic transglycosylase activity
BAY22_04170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BAY22_04180	COG1953	Uracil, thiamine, allantoin
BAY22_04210	COG3657	addiction module killer protein
BAY22_04270	COG0582	viral genome integration into host DNA
BAY22_04275	COG1943	Transposase
BAY22_04295	COG2867	negative regulation of translational initiation
BAY22_04305	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAY22_04310	COG0497	DNA recombination
BAY22_04315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BAY22_04330	COG2009	succinate dehydrogenase
BAY22_04335	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BAY22_04340	COG1053	succinate dehydrogenase
BAY22_04355	COG0508	dehydrogenase complex catalyzes the overall conversion of
BAY22_04365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BAY22_04370	COG1271	oxidase subunit
BAY22_04375	COG1294	oxidase, subunit
BAY22_04380	COG4890	Cyd operon protein YbgT
BAY22_04385	COG3790	cyd operon protein YbgE
BAY22_04390	COG0824	Thioesterase
BAY22_04395	COG0811	peptide transport
BAY22_04400	COG0848	biopolymer transport protein
BAY22_04405	COG3064	Membrane
BAY22_04405	COG3064	Membrane
BAY22_04415	COG2885	chlorophyll binding
BAY22_04420	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BAY22_04455	COG1230	cation diffusion facilitator family transporter
BAY22_04460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BAY22_04475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BAY22_04490	COG2017	converts alpha-aldose to the beta-anomer
BAY22_04505	COG1085	galactose-1-phosphate uridylyltransferase
BAY22_04510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BAY22_04525	COG1119	ATPase activity
BAY22_04530	COG3585	molybdate ion transport
BAY22_04530	COG2005	Transcriptional regulator
BAY22_04540	COG0725	ABC transporter, periplasmic molybdate-binding protein
BAY22_04545	COG4149	molybdate abc transporter
BAY22_04555	COG0561	phosphatase activity
BAY22_04580	COG2226	methyltransferase
BAY22_04585	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BAY22_04595	COG0556	nucleotide-excision repair
BAY22_04600	COG4628	conserved protein (DUF2132)
BAY22_04605	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BAY22_04615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BAY22_04625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BAY22_04630	COG0314	molybdopterin synthase activity
BAY22_04635	COG0670	Belongs to the BI1 family
BAY22_04640	COG1943	Transposase
BAY22_04660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BAY22_04665	COG0583	DNA-binding transcription factor activity
BAY22_04675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BAY22_04685	COG1943	Transposase
BAY22_04695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BAY22_04705	COG1686	Belongs to the peptidase S11 family
BAY22_04710	COG0277	FAD linked oxidase domain protein
BAY22_04720	COG1403	HNH endonuclease
BAY22_04730	COG2261	transglycosylase associated protein
BAY22_04740	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BAY22_04755	COG4807	Protein conserved in bacteria
BAY22_04775	COG1122	ATPase activity
BAY22_04780	COG0410	ABC transporter
BAY22_04795	COG2897	thiosulfate sulfurtransferase activity
BAY22_04800	COG1732	Glycine betaine
BAY22_04805	COG1732	Glycine betaine
BAY22_04810	COG1174	glycine betaine transport
BAY22_04815	COG1125	glycine betaine transport
BAY22_04820	COG1174	glycine betaine transport
BAY22_04825	COG0531	amino acid
BAY22_04830	COG1982	Orn Lys Arg decarboxylase major
BAY22_04840	COG0697	spore germination
BAY22_04865	COG0814	amino acid
BAY22_04880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BAY22_04910	COG2205	protein histidine kinase activity
BAY22_04910	COG0784	Response regulator, receiver
BAY22_04920	COG0642	Histidine kinase
BAY22_04920	COG2198	Histidine kinase
BAY22_04925	COG0642	Histidine kinase
BAY22_04925	COG2198	Histidine kinase
BAY22_04930	COG2223	nitrite transmembrane transporter activity
BAY22_04935	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BAY22_04940	COG1943	Transposase
BAY22_04945	COG1943	Transposase
BAY22_04960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BAY22_05005	COG3395	kinase activity
BAY22_05015	COG1349	DNA-binding transcription factor activity
BAY22_05020	COG3622	Belongs to the hyi family
BAY22_05040	COG4386	tail sheath protein
BAY22_05080	COG3299	homolog of phage Mu protein gp47
BAY22_05100	COG1737	Transcriptional regulator
BAY22_05105	COG2723	6-phospho-beta-galactosidase activity
BAY22_05120	COG3157	Type VI secretion system effector, Hcp
BAY22_05135	COG3083	sulfuric ester hydrolase activity
BAY22_05140	COG3082	Protein of unknown function (DUF1414)
BAY22_05150	COG1943	Transposase
BAY22_05160	COG1061	Type III restriction enzyme res subunit
BAY22_05165	COG1187	pseudouridine synthase activity
BAY22_05170	COG2814	Major facilitator Superfamily
BAY22_05180	COG4172	Belongs to the ABC transporter superfamily
BAY22_05185	COG4239	(ABC) transporter, permease
BAY22_05190	COG4174	ABC transporter (Permease)
BAY22_05195	COG4166	transmembrane transport
BAY22_05200	COG2200	EAL domain
BAY22_05205	COG0791	NLP P60 protein
BAY22_05210	COG0671	phosphoesterase, PA-phosphatase related
BAY22_05215	COG0523	cobalamin synthesis protein
BAY22_05225	COG2186	Transcriptional regulator
BAY22_05230	COG0246	Mannitol dehydrogenase
BAY22_05235	COG1312	Catalyzes the dehydration of D-mannonate
BAY22_05255	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_05280	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BAY22_05290	COG1129	ABC transporter
BAY22_05295	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_05300	COG0494	nUDIX hydrolase
BAY22_05310	COG1105	Belongs to the carbohydrate kinase PfkB family
BAY22_05315	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BAY22_05315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAY22_05315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAY22_05320	COG3710	Transcriptional regulator
BAY22_05335	COG3121	Chaperone
BAY22_05340	COG3188	usher protein
BAY22_05350	COG2855	membrane
BAY22_05355	COG0583	DNA-binding transcription factor activity
BAY22_05360	COG0833	amino acid
BAY22_05370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BAY22_05380	COG4771	TonB-dependent receptor
BAY22_05385	COG0625	glutathione transferase activity
BAY22_05410	COG2011	ABC-type metal ion transport system permease component
BAY22_05415	COG1686	Belongs to the peptidase S11 family
BAY22_05425	COG0814	amino acid
BAY22_05430	COG1349	DNA-binding transcription factor activity
BAY22_05435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BAY22_05440	COG0671	phosphoesterase, PA-phosphatase related
BAY22_05450	COG2985	domain, Protein
BAY22_05450	COG0569	domain protein
BAY22_05455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BAY22_05475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BAY22_05480	COG3842	ATPase activity
BAY22_05485	COG1176	ABC-type spermidine putrescine transport system, permease component I
BAY22_05490	COG1177	transmembrane transport
BAY22_05550	COG1120	ATPase activity
BAY22_05570	COG4160	amino acid transport
BAY22_05575	COG4215	(ABC) transporter
BAY22_05580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAY22_05585	COG1126	abc transporter atp-binding protein
BAY22_05590	COG1605	Chorismate mutase
BAY22_05600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAY22_05605	COG0702	epimerase
BAY22_05610	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BAY22_05615	COG0028	Belongs to the TPP enzyme family
BAY22_05620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BAY22_05630	COG2431	L-lysine efflux transmembrane transporter activity
BAY22_05635	COG3593	DNA synthesis involved in DNA repair
BAY22_05640	COG2990	Protein conserved in bacteria
BAY22_05645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAY22_05655	COG1278	Cold shock
BAY22_05665	COG0542	response to heat
BAY22_05670	COG1943	Transposase
BAY22_05675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BAY22_05685	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BAY22_05700	COG0492	ferredoxin-NADP+ reductase activity
BAY22_05710	COG1674	ftsk spoiiie
BAY22_05710	COG3107	peptidoglycan biosynthetic process
BAY22_05720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BAY22_05730	COG2814	Major facilitator Superfamily
BAY22_05735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BAY22_05745	COG1882	Formate acetyltransferase
BAY22_05750	COG2116	formate transmembrane transporter activity
BAY22_05755	COG1944	ATP diphosphatase activity
BAY22_05760	COG0252	asparaginase activity
BAY22_05765	COG5295	Hep Hag repeat protein
BAY22_05765	COG5295	Hep Hag repeat protein
BAY22_05790	COG0539	negative regulation of cytoplasmic translation
BAY22_05800	COG2333	competence protein COMEC
BAY22_05800	COG0658	competence protein
BAY22_05815	COG5383	Protein conserved in bacteria
BAY22_05825	COG1278	Cold shock
BAY22_05830	COG2835	tetraacyldisaccharide 4'-kinase activity
BAY22_05840	COG3173	Aminoglycoside phosphotransferase
BAY22_05850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BAY22_05855	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BAY22_05860	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BAY22_05875	COG1943	Transposase
BAY22_05880	COG2989	Protein conserved in bacteria
BAY22_05885	COG3108	Peptidase M15
BAY22_05890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BAY22_05895	COG1448	Aminotransferase
BAY22_05915	COG0308	aminopeptidase N
BAY22_05930	COG0633	Ferredoxin
BAY22_05930	COG3217	Mosc domain protein beta barrel domain protein
BAY22_05940	COG0488	(ABC) transporter
BAY22_05945	COG2995	paraquat-inducible protein a
BAY22_05950	COG3008	intermembrane lipid transfer
BAY22_05950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BAY22_05955	COG3009	Protein conserved in bacteria
BAY22_05965	COG3130	regulation of translation
BAY22_05975	COG1943	Transposase
BAY22_05995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BAY22_06010	COG1067	ATP-dependent peptidase activity
BAY22_06020	COG1943	Transposase
BAY22_06025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BAY22_06025	COG2885	chlorophyll binding
BAY22_06035	COG3070	regulator of competence-specific genes
BAY22_06040	COG1289	transmembrane transporter activity
BAY22_06045	COG3304	Inner membrane component domain
BAY22_06050	COG0210	DNA helicase
BAY22_06060	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BAY22_06065	COG1832	CoA-binding protein
BAY22_06085	COG2920	part of a sulfur-relay system
BAY22_06120	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_06130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BAY22_06135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BAY22_06140	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_06145	COG3425	synthase
BAY22_06155	COG1024	Enoyl-CoA hydratase
BAY22_06160	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_06170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BAY22_06175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BAY22_06310	COG0488	(ABC) transporter
BAY22_06320	COG3328	transposase activity
BAY22_06330	COG0303	'Molybdopterin
BAY22_06340	COG1136	(ABC) transporter
BAY22_06370	COG0583	DNA-binding transcription factor activity
BAY22_06375	COG0477	Major facilitator Superfamily
BAY22_06385	COG2311	Membrane
BAY22_06400	COG4211	Belongs to the binding-protein-dependent transport system permease family
BAY22_06405	COG2949	membrane
BAY22_06420	COG1346	cytolysis
BAY22_06430	COG2814	Major facilitator Superfamily
BAY22_06465	COG1943	Transposase
BAY22_06475	COG0489	protein tyrosine kinase activity
BAY22_06495	COG1253	flavin adenine dinucleotide binding
BAY22_06500	COG4114	ferric iron reductase
BAY22_06505	COG0076	glutamate decarboxylase activity
BAY22_06510	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BAY22_06525	COG1120	ATPase activity
BAY22_06530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BAY22_06535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BAY22_06540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BAY22_06555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BAY22_06560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BAY22_06570	COG0140	phosphoribosyl-ATP diphosphatase activity
BAY22_06570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BAY22_06585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BAY22_06590	COG0131	Imidazoleglycerol-phosphate dehydratase
BAY22_06590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BAY22_06600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BAY22_06610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAY22_06615	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_06620	COG1129	ABC transporter
BAY22_06625	COG1129	ABC transporter
BAY22_06630	COG0371	Dehydrogenase
BAY22_06640	COG0531	amino acid
BAY22_06645	COG2925	Exonuclease
BAY22_06660	COG3328	transposase activity
BAY22_06665	COG1388	LysM domain
BAY22_06665	COG1470	cell adhesion involved in biofilm formation
BAY22_06670	COG2271	Major facilitator Superfamily
BAY22_06675	COG3011	Protein conserved in bacteria
BAY22_06680	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_06690	COG4948	Mandelate Racemase Muconate Lactonizing
BAY22_06705	COG0534	Mate efflux family protein
BAY22_06725	COG3122	Protein conserved in bacteria
BAY22_06750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BAY22_06770	COG2223	nitrite transmembrane transporter activity
BAY22_06775	COG3328	transposase activity
BAY22_06800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BAY22_06805	COG3328	transposase activity
BAY22_06810	COG1530	ribonuclease E activity
BAY22_06815	COG0564	pseudouridine synthase activity
BAY22_06820	COG1943	Transposase
BAY22_06830	COG1399	metal-binding, possibly nucleic acid-binding protein
BAY22_06835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BAY22_06855	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_06865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BAY22_06870	COG1943	Transposase
BAY22_06875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BAY22_06880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BAY22_06890	COG0470	DNA polymerase III
BAY22_06895	COG0084	hydrolase, TatD family'
BAY22_06900	COG1263	PTS System
BAY22_06900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAY22_06905	COG1943	Transposase
BAY22_06915	COG0537	adenosine 5'-monophosphoramidase activity
BAY22_06920	COG5633	Lipoprotein
BAY22_06935	COG1472	Belongs to the glycosyl hydrolase 3 family
BAY22_06945	COG1252	NADH dehydrogenase
BAY22_06960	COG3328	transposase activity
BAY22_06975	COG3134	Outer membrane lipoprotein
BAY22_06980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BAY22_06985	COG4591	ABC-type transport system involved in lipoprotein release permease component
BAY22_06995	COG4591	ABC-type transport system involved in lipoprotein release permease component
BAY22_07005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BAY22_07015	COG2850	peptidyl-arginine hydroxylation
BAY22_07025	COG0745	RESPONSE REGULATOR receiver
BAY22_07035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BAY22_07055	COG1187	pseudouridine synthase activity
BAY22_07060	COG0538	isocitrate dehydrogenase activity
BAY22_07075	COG0840	transmembrane signaling receptor activity
BAY22_07080	COG0702	epimerase
BAY22_07085	COG1733	regulation of RNA biosynthetic process
BAY22_07110	COG1522	sequence-specific DNA binding
BAY22_07120	COG0604	alcohol dehydrogenase
BAY22_07120	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_07120	COG3321	synthase
BAY22_07130	COG1278	Cold shock
BAY22_07150	COG1285	pathogenesis
BAY22_07180	COG0643	Histidine kinase
BAY22_07180	COG2198	Histidine kinase
BAY22_07185	COG0835	chemotaxis
BAY22_07190	COG2271	Major facilitator Superfamily
BAY22_07195	COG0251	oxidation-reduction process
BAY22_07205	COG2964	Protein conserved in bacteria
BAY22_07225	COG0840	transmembrane signaling receptor activity
BAY22_07230	COG0840	transmembrane signaling receptor activity
BAY22_07235	COG0840	transmembrane signaling receptor activity
BAY22_07240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BAY22_07250	COG0745	RESPONSE REGULATOR receiver
BAY22_07255	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BAY22_07265	COG3023	N-Acetylmuramoyl-L-alanine amidase
BAY22_07270	COG5295	Hep Hag repeat protein
BAY22_07280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BAY22_07335	COG3121	Chaperone
BAY22_07355	COG3008	intermembrane lipid transfer
BAY22_07360	COG2995	paraquat-inducible protein a
BAY22_07365	COG1956	GAF domain-containing protein
BAY22_07375	COG0793	Belongs to the peptidase S41A family
BAY22_07385	COG3539	Fimbrial protein
BAY22_07390	COG3121	Chaperone
BAY22_07405	COG3121	Chaperone
BAY22_07410	COG2814	Major facilitator Superfamily
BAY22_07415	COG0823	Involved in the tonB-independent uptake of proteins
BAY22_07425	COG3023	N-Acetylmuramoyl-L-alanine amidase
BAY22_07435	COG1988	membrane-bound metal-dependent
BAY22_07440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BAY22_07445	COG1653	transport
BAY22_07450	COG3842	ATPase activity
BAY22_07455	COG0395	ABC-type sugar transport system, permease component
BAY22_07460	COG1175	transmembrane transport
BAY22_07470	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_07480	COG1917	Cupin 2, conserved barrel domain protein
BAY22_07485	COG3328	transposase activity
BAY22_07540	COG2207	Transcriptional regulator
BAY22_07595	COG1278	Cold shock
BAY22_07605	COG2226	methyltransferase
BAY22_07615	COG5002	protein histidine kinase activity
BAY22_07615	COG5001	Diguanylate cyclase
BAY22_07615	COG3447	MASE1 domain protein
BAY22_07635	COG3716	PTS system mannose fructose sorbose family IID component
BAY22_07640	COG3715	PTS system
BAY22_07645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_07645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAY22_07650	COG1253	flavin adenine dinucleotide binding
BAY22_07655	COG1846	Transcriptional regulator
BAY22_07670	COG1012	belongs to the aldehyde dehydrogenase family
BAY22_07675	COG3384	dioxygenase
BAY22_07685	COG3971	2-oxopent-4-enoate hydratase activity
BAY22_07700	COG2368	4-hydroxyphenylacetate
BAY22_07705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BAY22_07710	COG1760	l-serine dehydratase
BAY22_07735	COG0513	Belongs to the DEAD box helicase family
BAY22_07740	COG3141	response to X-ray
BAY22_07755	COG1770	oligopeptidase
BAY22_07770	COG1528	Iron-storage protein
BAY22_07775	COG2372	response to copper ion
BAY22_07805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BAY22_07810	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BAY22_07825	COG1943	Transposase
BAY22_07835	COG3418	PFAM FlgN family protein
BAY22_07840	COG2747	anti-sigma28 factor FlgM
BAY22_07850	COG1815	bacterial-type flagellum-dependent cell motility
BAY22_07855	COG1558	bacterial-type flagellum-dependent cell motility
BAY22_07860	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BAY22_07865	COG1749	Flagellar hook protein flgE
BAY22_07895	COG1256	bacterial-type flagellum assembly
BAY22_07905	COG2390	Transcriptional regulator
BAY22_07910	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_07910	COG3347	Dehydrogenase
BAY22_07915	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_07925	COG1129	ABC transporter
BAY22_07935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAY22_07955	COG1987	bacterial-type flagellum assembly
BAY22_07980	COG1580	Controls the rotational direction of flagella during chemotaxis
BAY22_07990	COG2882	bacterial-type flagellum organization
BAY22_07995	COG1157	protein secretion by the type III secretion system
BAY22_08005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BAY22_08015	COG1677	Flagellar hook-basal body complex protein FliE
BAY22_08030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BAY22_08035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BAY22_08040	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BAY22_08075	COG1191	sigma factor activity
BAY22_08085	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BAY22_08115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BAY22_08115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BAY22_08115	COG0506	proline dehydrogenase activity
BAY22_08140	COG2837	iron assimilation
BAY22_08155	COG1113	amino acid transport
BAY22_08180	COG3136	membrane protein required for alginate biosynthesis
BAY22_08190	COG2197	response regulator
BAY22_08340	COG0673	inositol 2-dehydrogenase activity
BAY22_08350	COG1175	transmembrane transport
BAY22_08355	COG0395	ABC-type sugar transport system, permease component
BAY22_08415	COG0402	S-adenosylhomocysteine deaminase activity
BAY22_08430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BAY22_08435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BAY22_08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAY22_08485	COG3328	transposase activity
BAY22_08510	COG0500	methyltransferase
BAY22_08550	COG5002	protein histidine kinase activity
BAY22_08605	COG0012	GTP binding
BAY22_08625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BAY22_08655	COG2890	protein-(glutamine-N5) methyltransferase activity
BAY22_08660	COG3094	Invasion gene expression up-regulator, SirB
BAY22_08665	COG2912	Transglutaminase-like superfamily
BAY22_08675	COG1943	Transposase
BAY22_08680	COG0659	secondary active sulfate transmembrane transporter activity
BAY22_08720	COG3833	ABC-type maltose transport systems, permease component
BAY22_08725	COG1176	ABC-type spermidine putrescine transport system, permease component I
BAY22_08735	COG1943	Transposase
BAY22_08740	COG3842	ATPase activity
BAY22_08745	COG0584	glycerophosphoryl diester phosphodiesterase
BAY22_08765	COG3381	protein complex oligomerization
BAY22_08780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BAY22_08785	COG0673	inositol 2-dehydrogenase activity
BAY22_08810	COG3102	Protein conserved in bacteria
BAY22_08830	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BAY22_08835	COG1801	Protein of unknown function DUF72
BAY22_08845	COG0494	nUDIX hydrolase
BAY22_08870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BAY22_08880	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BAY22_08885	COG0739	heme binding
BAY22_08890	COG1560	Kdo2-lipid A biosynthetic process
BAY22_08895	COG0469	pyruvate kinase activity
BAY22_08900	COG1737	Transcriptional regulator
BAY22_08905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BAY22_08910	COG0800	Aldolase
BAY22_08925	COG0251	oxidation-reduction process
BAY22_08930	COG1199	ATP-dependent helicase activity
BAY22_08940	COG3065	identical protein binding
BAY22_08945	COG0318	PFAM AMP-dependent synthetase and ligase
BAY22_08950	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BAY22_08955	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BAY22_08960	COG2894	cell division
BAY22_08975	COG2951	lytic endotransglycosylase activity
BAY22_08980	COG0179	Fumarylacetoacetate (FAA) hydrolase
BAY22_08990	COG0582	viral genome integration into host DNA
BAY22_09090	COG3328	transposase activity
BAY22_09175	COG1943	Transposase
BAY22_09260	COG3328	transposase activity
BAY22_09270	COG1104	cysteine desulfurase activity
BAY22_09300	COG2719	SpoVR family
BAY22_09310	COG2814	Major facilitator Superfamily
BAY22_09320	COG0583	DNA-binding transcription factor activity
BAY22_09335	COG2766	serine protein kinase
BAY22_09340	COG3713	MltA-interacting MipA family protein
BAY22_09360	COG3139	Protein of unknown function (DUF1315)
BAY22_09365	COG1335	isochorismatase
BAY22_09370	COG0252	asparaginase activity
BAY22_09375	COG0616	signal peptide processing
BAY22_09380	COG0778	Nitroreductase
BAY22_09385	COG0709	Synthesizes selenophosphate from selenide and ATP
BAY22_09390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BAY22_09400	COG0494	nUDIX hydrolase
BAY22_09405	COG0708	Exodeoxyribonuclease III
BAY22_09410	COG0583	DNA-binding transcription factor activity
BAY22_09430	COG3328	transposase activity
BAY22_09435	COG0788	formyltetrahydrofolate deformylase activity
BAY22_09445	COG0745	RESPONSE REGULATOR receiver
BAY22_09460	COG1435	thymidine kinase activity
BAY22_09475	COG1454	alcohol dehydrogenase
BAY22_09475	COG1012	belongs to the aldehyde dehydrogenase family
BAY22_09480	COG2095	MarC family integral membrane protein
BAY22_09490	COG0601	transmembrane transport
BAY22_09495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAY22_09500	COG0444	Belongs to the ABC transporter superfamily
BAY22_09545	COG2350	Protein conserved in bacteria
BAY22_09550	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BAY22_09555	COG3328	transposase activity
BAY22_09560	COG1607	acyl-coa hydrolase
BAY22_09590	COG3047	cAMP biosynthetic process
BAY22_09610	COG0135	phosphoribosylanthranilate isomerase activity
BAY22_09610	COG0134	indole-3-glycerol-phosphate synthase activity
BAY22_09620	COG0512	Glutamine amidotransferase of anthranilate synthase
BAY22_09645	COG0009	L-threonylcarbamoyladenylate synthase
BAY22_09650	COG1187	pseudouridine synthase activity
BAY22_09660	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_09665	COG0616	signal peptide processing
BAY22_09680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BAY22_09685	COG0583	DNA-binding transcription factor activity
BAY22_09695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BAY22_09700	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BAY22_09705	COG0671	phosphoesterase, PA-phosphatase related
BAY22_09710	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BAY22_09715	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BAY22_09730	COG0023	Translation Initiation Factor
BAY22_09750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BAY22_09755	COG2879	small protein
BAY22_09760	COG1966	Carbon starvation protein
BAY22_09770	COG2271	Major facilitator Superfamily
BAY22_09775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAY22_09780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BAY22_09790	COG4659	FMN binding
BAY22_09795	COG4658	electron transport chain
BAY22_09800	COG2207	Transcriptional regulator
BAY22_09800	COG3708	Transcriptional regulator
BAY22_09830	COG1132	(ABC) transporter
BAY22_09840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAY22_09845	COG2274	protein secretion by the type I secretion system
BAY22_09860	COG1879	ABC-type sugar transport system periplasmic component
BAY22_09870	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_09880	COG0673	inositol 2-dehydrogenase activity
BAY22_09885	COG0385	Bile acid
BAY22_09920	COG0114	fumarate hydratase activity
BAY22_09940	COG1940	carbohydrate kinase activity
BAY22_09945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BAY22_09950	COG0038	chloride channel
BAY22_10000	COG4128	Pfam Zonular occludens toxin
BAY22_10060	COG4128	Pfam Zonular occludens toxin
BAY22_10080	COG1609	Transcriptional regulator
BAY22_10090	COG1879	ABC-type sugar transport system periplasmic component
BAY22_10095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BAY22_10100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BAY22_10105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAY22_10130	COG0028	Belongs to the TPP enzyme family
BAY22_10135	COG0440	acetolactate synthase activity
BAY22_10140	COG1011	Hydrolase
BAY22_10160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BAY22_10165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BAY22_10170	COG0589	response to stress
BAY22_10175	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BAY22_10180	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BAY22_10195	COG0531	amino acid
BAY22_10205	COG0745	RESPONSE REGULATOR receiver
BAY22_10210	COG2205	protein histidine kinase activity
BAY22_10215	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BAY22_10220	COG1943	Transposase
BAY22_10245	COG3038	cytochrome b561
BAY22_10260	COG3591	Belongs to the peptidase S1B family
BAY22_10275	COG1643	Atp-dependent helicase
BAY22_10285	COG2390	Transcriptional regulator
BAY22_10290	COG0246	Mannitol dehydrogenase
BAY22_10295	COG3784	Protein of unknown function (DUF1318)
BAY22_10310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BAY22_10315	COG3187	Heat shock protein
BAY22_10320	COG3042	response to heat
BAY22_10325	COG1285	pathogenesis
BAY22_10345	COG2755	lipolytic protein G-D-S-L family
BAY22_10345	COG0657	acetylesterase activity
BAY22_10360	COG4166	transmembrane transport
BAY22_10365	COG2866	Carboxypeptidase
BAY22_10370	COG4948	Mandelate Racemase Muconate Lactonizing
BAY22_10375	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BAY22_10380	COG1943	Transposase
BAY22_10405	COG3106	COG3106 Predicted ATPase
BAY22_10415	COG1983	PspC domain protein
BAY22_10425	COG1842	Phage shock protein A
BAY22_10430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BAY22_10435	COG1943	Transposase
BAY22_10450	COG4166	transmembrane transport
BAY22_10455	COG4168	peptide transport system, permease
BAY22_10460	COG4171	peptide transport system, permease
BAY22_10470	COG4172	Belongs to the ABC transporter superfamily
BAY22_10475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BAY22_10475	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BAY22_10480	COG3104	oligopeptide transport
BAY22_10505	COG0625	glutathione transferase activity
BAY22_10525	COG3895	Periplasmic Protein
BAY22_10535	COG3133	Outer membrane lipoprotein
BAY22_10545	COG4989	oxidoreductase activity
BAY22_10550	COG3313	Fe-S protein
BAY22_10555	COG2194	sulfuric ester hydrolase activity
BAY22_10560	COG1309	transcriptional regulator
BAY22_10565	COG1902	pentaerythritol trinitrate reductase activity
BAY22_10575	COG0346	lactoylglutathione lyase activity
BAY22_10580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BAY22_10585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BAY22_10595	COG0791	NLP P60 protein
BAY22_10600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BAY22_10610	COG0583	DNA-binding transcription factor activity
BAY22_10615	COG2814	Major facilitator Superfamily
BAY22_10620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BAY22_10625	COG0307	riboflavin synthase, alpha
BAY22_10650	COG4238	major outer membrane lipoprotein
BAY22_10655	COG1943	Transposase
BAY22_10670	COG1388	LysM domain
BAY22_10670	COG1376	ErfK ybiS ycfS ynhG family protein
BAY22_10685	COG0719	Fe-S assembly protein
BAY22_10690	COG0396	ATPase activity
BAY22_10695	COG0719	Fe-S assembly protein
BAY22_10700	COG0316	Belongs to the HesB IscA family
BAY22_10710	COG2050	protein possibly involved in aromatic compounds catabolism
BAY22_10715	COG0247	lactate metabolic process
BAY22_10715	COG0277	FAD linked oxidase domain protein
BAY22_10720	COG0628	permease
BAY22_10730	COG0574	Belongs to the PEP-utilizing enzyme family
BAY22_10730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BAY22_10755	COG0791	NLP P60 protein
BAY22_10795	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BAY22_10800	COG0386	Belongs to the glutathione peroxidase family
BAY22_10815	COG0776	regulation of translation
BAY22_10820	COG0072	phenylalanine-tRNA ligase activity
BAY22_10820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAY22_10825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BAY22_10850	COG4249	Peptidase C14 caspase catalytic subunit p20
BAY22_10875	COG0803	Belongs to the bacterial solute-binding protein 9 family
BAY22_10880	COG1121	(ABC) transporter
BAY22_10885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BAY22_10890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BAY22_10910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BAY22_10915	COG3328	transposase activity
BAY22_10930	COG0628	permease
BAY22_10960	COG3916	Acyl-homoserine-lactone synthase
BAY22_10965	COG2771	luxR family
BAY22_10970	COG0583	DNA-binding transcription factor activity
BAY22_10980	COG0477	Major facilitator Superfamily
BAY22_10990	COG0667	Aldo Keto reductase
BAY22_11020	COG1203	CRISPR-associated helicase, Cas3
BAY22_11025	COG1518	maintenance of DNA repeat elements
BAY22_11030	COG0668	transmembrane transport
BAY22_11050	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BAY22_11055	COG0395	ABC-type sugar transport system, permease component
BAY22_11070	COG1609	Transcriptional regulator
BAY22_11080	COG3842	ATPase activity
BAY22_11090	COG3210	domain, Protein
BAY22_11110	COG3210	domain, Protein
BAY22_11135	COG2831	hemolysin activation secretion protein
BAY22_11140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BAY22_11145	COG4638	Rieske (2fe-2S)
BAY22_11150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BAY22_11155	COG0473	3-isopropylmalate dehydrogenase activity
BAY22_11160	COG0583	DNA-binding transcription factor activity
BAY22_11165	COG1609	Transcriptional regulator
BAY22_11175	COG1129	ABC transporter
BAY22_11180	COG1879	ABC-type sugar transport system periplasmic component
BAY22_11185	COG1063	alcohol dehydrogenase
BAY22_11205	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BAY22_11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAY22_11240	COG0765	amino acid transport
BAY22_11245	COG1126	abc transporter atp-binding protein
BAY22_11275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BAY22_11290	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BAY22_11305	COG1169	isochorismate synthase
BAY22_11315	COG4575	ribosome binding
BAY22_11330	COG0129	dihydroxy-acid dehydratase activity
BAY22_11345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BAY22_11355	COG1609	Transcriptional regulator
BAY22_11365	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_11370	COG3265	gluconokinase activity
BAY22_11375	COG2731	YhcH YjgK YiaL family protein
BAY22_11390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BAY22_11395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BAY22_11405	COG0839	Belongs to the complex I subunit 6 family
BAY22_11420	COG1034	ATP synthesis coupled electron transport
BAY22_11430	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BAY22_11440	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BAY22_11450	COG0583	DNA-binding transcription factor activity
BAY22_11460	COG0436	Aminotransferase
BAY22_11475	COG0471	metal ion transport
BAY22_11475	COG0490	domain, Protein
BAY22_11480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BAY22_11505	COG0857	belongs to the CobB CobQ family
BAY22_11505	COG0280	phosphate acetyltransferase
BAY22_11510	COG1609	Transcriptional regulator
BAY22_11525	COG3328	transposase activity
BAY22_11530	COG4953	penicillin-binding protein 1C
BAY22_11535	COG2373	Large extracellular alpha-helical protein
BAY22_11555	COG3962	Belongs to the TPP enzyme family
BAY22_11565	COG1879	ABC-type sugar transport system periplasmic component
BAY22_11570	COG1129	ABC transporter
BAY22_11575	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_11580	COG0673	inositol 2-dehydrogenase activity
BAY22_11585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAY22_11595	COG3718	enzyme involved in inositol metabolism
BAY22_11605	COG5265	(ABC) transporter
BAY22_11630	COG2197	response regulator
BAY22_11640	COG1278	Cold shock
BAY22_11645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BAY22_11655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BAY22_11675	COG1686	Belongs to the peptidase S11 family
BAY22_11685	COG0772	Belongs to the SEDS family
BAY22_11690	COG0768	penicillin binding
BAY22_11700	COG0799	negative regulation of ribosome biogenesis
BAY22_11710	COG1466	dna polymerase III delta subunit
BAY22_11725	COG2888	peptidyl-tyrosine sulfation
BAY22_11730	COG1126	abc transporter atp-binding protein
BAY22_11735	COG0765	amino acid transport
BAY22_11740	COG0765	amino acid transport
BAY22_11750	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BAY22_11755	COG4535	Mg2 and Co2 transporter CorC
BAY22_11765	COG1702	phosphate starvation-inducible protein PhoH
BAY22_11775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BAY22_11810	COG0367	asparagine synthase
BAY22_11815	COG0647	UMP catabolic process
BAY22_11820	COG1940	carbohydrate kinase activity
BAY22_11820	COG1846	Transcriptional regulator
BAY22_11825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BAY22_11835	COG2190	(PTS) system
BAY22_11835	COG1263	PTS System
BAY22_11835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAY22_11840	COG1943	Transposase
BAY22_11860	COG0735	belongs to the Fur family
BAY22_11880	COG0596	Alpha beta hydrolase
BAY22_11890	COG0582	viral genome integration into host DNA
BAY22_11895	COG2963	transposase activity
BAY22_11920	COG2113	Glycine betaine
BAY22_11925	COG4176	ABC-type proline glycine betaine transport system permease component
BAY22_11930	COG4175	Glycine betaine
BAY22_11935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BAY22_11970	COG3328	transposase activity
BAY22_11980	COG1278	Cold shock
BAY22_11985	COG0747	negative chemotaxis
BAY22_11995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAY22_12000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BAY22_12005	COG1124	(ABC) transporter
BAY22_12035	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BAY22_12045	COG4413	Urea transporter
BAY22_12050	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BAY22_12065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BAY22_12070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BAY22_12075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BAY22_12085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BAY22_12090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BAY22_12095	COG1447	Phosphotransferase system cellobiose-specific component IIA
BAY22_12100	COG1917	Cupin 2, conserved barrel domain protein
BAY22_12100	COG2169	Transcriptional regulator
BAY22_12120	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BAY22_12125	COG0033	Phosphoglucomutase
BAY22_12145	COG0745	RESPONSE REGULATOR receiver
BAY22_12150	COG2205	protein histidine kinase activity
BAY22_12185	COG3272	Protein of unknown function (DUF1722)
BAY22_12195	COG5212	phosphodiesterase
BAY22_12200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BAY22_12210	COG1984	allophanate hydrolase subunit 2
BAY22_12260	COG0513	Belongs to the DEAD box helicase family
BAY22_12270	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BAY22_12280	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BAY22_12285	COG3026	antisigma factor binding
BAY22_12290	COG3086	response to oxidative stress
BAY22_12305	COG0681	Belongs to the peptidase S26 family
BAY22_12345	COG3501	Rhs element vgr protein
BAY22_12375	COG2824	Alkylphosphonate utilization operon protein PhnA
BAY22_12385	COG1704	LemA family
BAY22_12405	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BAY22_12410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BAY22_12415	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BAY22_12425	COG1138	Cytochrome C-type biogenesis protein
BAY22_12430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BAY22_12435	COG4235	cytochrome complex assembly
BAY22_12435	COG3088	subunit of a heme lyase
BAY22_12440	COG3088	subunit of a heme lyase
BAY22_12440	COG4235	cytochrome complex assembly
BAY22_12455	COG3691	Protein conserved in bacteria
BAY22_12470	COG2062	phosphohistidine phosphatase, SixA
BAY22_12480	COG2890	protein-(glutamine-N5) methyltransferase activity
BAY22_12490	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BAY22_12495	COG0730	response to heat
BAY22_12500	COG3101	peptidyl-lysine hydroxylation
BAY22_12515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BAY22_12520	COG1794	racemase activity, acting on amino acids and derivatives
BAY22_12535	COG0697	spore germination
BAY22_12555	COG1943	Transposase
BAY22_12560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BAY22_12570	COG0586	Pfam SNARE associated Golgi protein
BAY22_12580	COG0285	dihydrofolate synthase activity
BAY22_12585	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BAY22_12590	COG1286	toxin biosynthetic process
BAY22_12595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BAY22_12600	COG0163	prenyltransferase activity
BAY22_12605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAY22_12610	COG4215	(ABC) transporter
BAY22_12615	COG4160	amino acid transport
BAY22_12620	COG4598	ABC transporter
BAY22_12625	COG1090	epimerase
BAY22_12635	COG0622	Phosphoesterase
BAY22_12640	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BAY22_12645	COG3037	sugar-specific permease SgaT UlaA
BAY22_12650	COG3328	transposase activity
BAY22_12655	COG4953	penicillin-binding protein 1C
BAY22_12660	COG3423	Transcriptional regulator
BAY22_12710	COG2850	peptidyl-arginine hydroxylation
BAY22_12715	COG3328	transposase activity
BAY22_12750	COG0656	L-ascorbic acid biosynthetic process
BAY22_12755	COG0667	Aldo Keto reductase
BAY22_12790	COG0671	phosphoesterase, PA-phosphatase related
BAY22_12790	COG2453	phosphatase
BAY22_12795	COG2267	carboxylic ester hydrolase activity
BAY22_12805	COG4589	Belongs to the CDS family
BAY22_12810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BAY22_12860	COG2501	S4 domain
BAY22_12865	COG1943	Transposase
BAY22_12880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BAY22_12885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BAY22_12905	COG0581	inorganic phosphate transmembrane transporter activity
BAY22_12915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BAY22_12920	COG0248	Ppx GppA phosphatase
BAY22_12930	COG2239	Acts as a magnesium transporter
BAY22_12935	COG0443	Heat shock 70 kDa protein
BAY22_12940	COG1177	transmembrane transport
BAY22_12945	COG1176	ABC-type spermidine putrescine transport system, permease component I
BAY22_12955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BAY22_12965	COG3842	ATPase activity
BAY22_12990	COG2205	protein histidine kinase activity
BAY22_12995	COG2205	protein histidine kinase activity
BAY22_13000	COG0745	RESPONSE REGULATOR receiver
BAY22_13005	COG3422	double-strand break repair
BAY22_13030	COG0351	phosphomethylpyrimidine kinase
BAY22_13045	COG3328	transposase activity
BAY22_13080	COG1943	Transposase
BAY22_13095	COG0517	IMP dehydrogenase activity
BAY22_13095	COG0516	GMP reductase activity
BAY22_13105	COG1645	bacterial-type flagellum-dependent swarming motility
BAY22_13120	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAY22_13125	COG2976	Protein conserved in bacteria
BAY22_13170	COG3468	outer membrane autotransporter barrel domain protein
BAY22_13175	COG3468	outer membrane autotransporter barrel domain protein
BAY22_13195	COG2975	iron-sulfur cluster assembly
BAY22_13200	COG0633	Ferredoxin
BAY22_13205	COG0443	Heat shock 70 kDa protein
BAY22_13220	COG0822	iron-sulfur transferase activity
BAY22_13225	COG1104	cysteine desulfurase activity
BAY22_13240	COG0483	inositol monophosphate 1-phosphatase activity
BAY22_13245	COG1943	Transposase
BAY22_13250	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BAY22_13255	COG3683	transport system, periplasmic component
BAY22_13260	COG3711	transcriptional antiterminator
BAY22_13265	COG2814	Major facilitator Superfamily
BAY22_13285	COG1017	nitric oxide dioxygenase activity
BAY22_13285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BAY22_13290	COG2188	Transcriptional regulator
BAY22_13295	COG2188	Transcriptional regulator
BAY22_13300	COG0347	Belongs to the P(II) protein family
BAY22_13305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BAY22_13305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BAY22_13310	COG2204	response regulator
BAY22_13315	COG3170	Tfp pilus assembly protein FimV
BAY22_13320	COG2205	protein histidine kinase activity
BAY22_13325	COG1943	Transposase
BAY22_13355	COG0590	tRNA wobble adenosine to inosine editing
BAY22_13360	COG0560	Phosphoserine phosphatase
BAY22_13370	COG1737	Transcriptional regulator
BAY22_13375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BAY22_13380	COG1943	Transposase
BAY22_13390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BAY22_13440	COG3188	usher protein
BAY22_13445	COG3328	transposase activity
BAY22_13450	COG3188	usher protein
BAY22_13455	COG3121	Chaperone
BAY22_13515	COG2951	lytic endotransglycosylase activity
BAY22_13550	COG0243	molybdopterin cofactor binding
BAY22_13555	COG0437	4 iron, 4 sulfur cluster binding
BAY22_13560	COG3302	dmso reductase anchor subunit
BAY22_13565	COG3381	protein complex oligomerization
BAY22_13595	COG3038	cytochrome b561
BAY22_13600	COG0436	Aminotransferase
BAY22_13625	COG0667	Aldo Keto reductase
BAY22_13640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BAY22_13680	COG1943	Transposase
BAY22_13705	COG3530	Putative quorum-sensing-regulated virulence factor
BAY22_13720	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BAY22_13725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BAY22_13730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_13740	COG2190	(PTS) system
BAY22_13745	COG1943	Transposase
BAY22_13755	COG2205	protein histidine kinase activity
BAY22_13760	COG0745	RESPONSE REGULATOR receiver
BAY22_13765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAY22_13780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BAY22_13790	COG0006	proline dipeptidase activity
BAY22_13800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BAY22_13810	COG3850	Histidine kinase
BAY22_13810	COG5002	protein histidine kinase activity
BAY22_13815	COG0745	RESPONSE REGULATOR receiver
BAY22_13830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BAY22_13835	COG4208	sulfate ABC transporter
BAY22_13840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BAY22_13845	COG4150	thiosulfate binding
BAY22_13855	COG1737	Transcriptional regulator
BAY22_13865	COG2731	YhcH YjgK YiaL family protein
BAY22_13875	COG4886	Leucine-rich repeat (LRR) protein
BAY22_13885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BAY22_13890	COG2837	iron assimilation
BAY22_13900	COG3111	PFAM Bacterial OB fold (BOF) protein
BAY22_13945	COG3005	denitrification pathway
BAY22_13950	COG3043	anaerobic respiration
BAY22_13960	COG3062	negative regulation of establishment of protein localization
BAY22_13965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BAY22_13965	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BAY22_13970	COG2197	response regulator
BAY22_13980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BAY22_13990	COG1988	membrane-bound metal-dependent
BAY22_13995	COG0641	radical SAM
BAY22_14000	COG3119	arylsulfatase activity
BAY22_14005	COG3842	ATPase activity
BAY22_14010	COG1175	transmembrane transport
BAY22_14015	COG1840	ABC-type Fe3 transport system, periplasmic component
BAY22_14025	COG1393	Belongs to the ArsC family
BAY22_14035	COG1876	peptidase activity
BAY22_14055	COG2321	neutral zinc metallopeptidase
BAY22_14065	COG1943	Transposase
BAY22_14070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BAY22_14080	COG2716	regulation of RNA biosynthetic process
BAY22_14085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BAY22_14105	COG0628	permease
BAY22_14110	COG4783	chaperone-mediated protein folding
BAY22_14115	COG1393	Belongs to the ArsC family
BAY22_14125	COG1943	Transposase
BAY22_14140	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BAY22_14150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BAY22_14155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BAY22_14160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BAY22_14165	COG4181	ATPase activity
BAY22_14170	COG2755	lipolytic protein G-D-S-L family
BAY22_14175	COG0300	oxidoreductase activity
BAY22_14180	COG3118	belongs to the thioredoxin family
BAY22_14185	COG0330	HflC and HflK could
BAY22_14190	COG1585	Membrane protein implicated in regulation of membrane protease activity
BAY22_14195	COG0789	Transcriptional regulator
BAY22_14205	COG3735	TraB family
BAY22_14210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BAY22_14220	COG0737	Belongs to the 5'-nucleotidase family
BAY22_14225	COG0737	Belongs to the 5'-nucleotidase family
BAY22_14230	COG0737	Belongs to the 5'-nucleotidase family
BAY22_14235	COG2223	nitrite transmembrane transporter activity
BAY22_14240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BAY22_14240	COG4651	solute:proton antiporter activity
BAY22_14245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAY22_14250	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BAY22_14310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BAY22_14330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BAY22_14330	COG0543	2 iron, 2 sulfur cluster binding
BAY22_14360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BAY22_14395	COG1196	nuclear chromosome segregation
BAY22_14395	COG3264	Mechanosensitive ion channel
BAY22_14400	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BAY22_14405	COG1309	transcriptional regulator
BAY22_14410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAY22_14415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BAY22_14425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BAY22_14450	COG3695	enzyme binding
BAY22_14455	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BAY22_14460	COG1946	Acyl-CoA thioesterase
BAY22_14465	COG0004	ammonium transporteR
BAY22_14470	COG0347	Belongs to the P(II) protein family
BAY22_14475	COG1132	(ABC) transporter
BAY22_14480	COG1132	(ABC) transporter
BAY22_14485	COG1522	sequence-specific DNA binding
BAY22_14500	COG4533	DNA binding
BAY22_14510	COG0824	Thioesterase
BAY22_14515	COG1555	photosystem II stabilization
BAY22_14520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BAY22_14525	COG0776	regulation of translation
BAY22_14530	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BAY22_14555	COG0271	Belongs to the BolA IbaG family
BAY22_14560	COG3056	Lipoprotein
BAY22_14565	COG2223	nitrite transmembrane transporter activity
BAY22_14575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BAY22_14580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BAY22_14585	COG1845	cytochrome c oxidase, subunit III
BAY22_14590	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BAY22_14600	COG2814	Major facilitator Superfamily
BAY22_14610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BAY22_14615	COG0693	protein deglycase activity
BAY22_14635	COG0142	geranyltranstransferase activity
BAY22_14645	COG1943	Transposase
BAY22_14650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BAY22_14655	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BAY22_14670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BAY22_14670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BAY22_14690	COG1943	Transposase
BAY22_14695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BAY22_14700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BAY22_14705	COG1862	Preprotein translocase
BAY22_14715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BAY22_14720	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BAY22_14725	COG0450	alkyl hydroperoxide reductase
BAY22_14730	COG1943	Transposase
BAY22_14755	COG0366	Alpha amylase catalytic
BAY22_14765	COG1114	Component of the transport system for branched-chain amino acids
BAY22_14775	COG5002	protein histidine kinase activity
BAY22_14780	COG0745	RESPONSE REGULATOR receiver
BAY22_14790	COG0420	3'-5' exonuclease activity
BAY22_14795	COG0419	ATPase involved in DNA repair
BAY22_14815	COG1940	carbohydrate kinase activity
BAY22_14910	COG2195	Cleaves the N-terminal amino acid of tripeptides
BAY22_14930	COG1477	protein flavinylation
BAY22_14950	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BAY22_14955	COG1805	sodium ion transport
BAY22_14960	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BAY22_14965	COG3034	peptidoglycan biosynthetic process
BAY22_14970	COG0121	glutamine amidotransferase
BAY22_14980	COG1960	acyl-CoA dehydrogenase activity
BAY22_14990	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BAY22_15015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BAY22_15030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BAY22_15080	COG2814	Major facilitator Superfamily
BAY22_15085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BAY22_15095	COG1846	Transcriptional regulator
BAY22_15100	COG1566	PFAM secretion protein HlyD family protein
BAY22_15105	COG2814	Major facilitator Superfamily
BAY22_15110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BAY22_15115	COG3118	belongs to the thioredoxin family
BAY22_15125	COG1042	CoA-binding domain protein
BAY22_15125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BAY22_15125	COG0045	succinate-CoA ligase (ADP-forming) activity
BAY22_15130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BAY22_15135	COG5544	Lipoprotein
BAY22_15170	COG0542	response to heat
BAY22_15180	COG0564	pseudouridine synthase activity
BAY22_15185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAY22_15190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BAY22_15195	COG1943	Transposase
BAY22_15215	COG0077	Prephenate dehydratase
BAY22_15215	COG1605	Chorismate mutase
BAY22_15220	COG1605	Chorismate mutase
BAY22_15220	COG0287	Prephenate dehydrogenase
BAY22_15225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BAY22_15230	COG3279	Response regulator of the LytR AlgR family
BAY22_15235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BAY22_15240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BAY22_15245	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BAY22_15250	COG3137	Salt-induced outer membrane protein
BAY22_15255	COG1943	Transposase
BAY22_15280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BAY22_15285	COG4137	Cytochrome C assembly protein
BAY22_15290	COG4536	flavin adenine dinucleotide binding
BAY22_15295	COG1943	Transposase
BAY22_15300	COG1943	Transposase
BAY22_15310	COG2918	glutathione biosynthetic process
BAY22_15315	COG1238	metal cluster binding
BAY22_15320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BAY22_15350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BAY22_15355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BAY22_15390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BAY22_15395	COG3958	Transketolase
BAY22_15400	COG3959	Transketolase, thiamine diphosphate binding domain
BAY22_15405	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_15410	COG1129	ABC transporter
BAY22_15430	COG3783	Cytochrome b(562)
BAY22_15435	COG3038	cytochrome b561
BAY22_15440	COG3381	protein complex oligomerization
BAY22_15445	COG3302	dmso reductase anchor subunit
BAY22_15450	COG0437	4 iron, 4 sulfur cluster binding
BAY22_15455	COG0243	molybdopterin cofactor binding
BAY22_15460	COG0235	Class ii aldolase
BAY22_15465	COG1349	DNA-binding transcription factor activity
BAY22_15475	COG1943	Transposase
BAY22_15480	COG1129	ABC transporter
BAY22_15485	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_15490	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_15495	COG3623	hexulose-6-phosphate isomerase
BAY22_15500	COG1070	Carbohydrate kinase
BAY22_15505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BAY22_15505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BAY22_15515	COG0024	Methionine aminopeptidase
BAY22_15530	COG4771	TonB-dependent receptor
BAY22_15540	COG1858	cytochrome C peroxidase
BAY22_15545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAY22_15565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BAY22_15580	COG2376	Dihydroxyacetone kinase
BAY22_15585	COG1028	Short-chain dehydrogenase reductase Sdr
BAY22_15590	COG1063	alcohol dehydrogenase
BAY22_15595	COG0698	ribose 5-phosphate isomerase
BAY22_15605	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BAY22_15610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BAY22_15615	COG4942	peptidase
BAY22_15615	COG1388	LysM domain
BAY22_15640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BAY22_15655	COG0529	Catalyzes the synthesis of activated sulfate
BAY22_15705	COG0720	synthase
BAY22_15710	COG0602	queuosine metabolic process
BAY22_15730	COG3956	TIGRFAM MazG family protein
BAY22_15740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BAY22_15745	COG3437	response regulator, receiver
BAY22_15745	COG2205	protein histidine kinase activity
BAY22_15745	COG4999	Histidine kinase
BAY22_15745	COG3850	Histidine kinase
BAY22_15750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BAY22_15760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAY22_15770	COG2860	membrane
BAY22_15790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BAY22_15795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BAY22_15805	COG1120	ATPase activity
BAY22_15810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BAY22_15815	COG1643	Atp-dependent helicase
BAY22_15820	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BAY22_15830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BAY22_15835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BAY22_15840	COG0617	tRNA 3'-terminal CCA addition
BAY22_15845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BAY22_15865	COG0726	polysaccharide deacetylase
BAY22_15870	COG0842	Transport permease protein
BAY22_15875	COG1131	(ABC) transporter
BAY22_15880	COG0288	reversible hydration of carbon dioxide
BAY22_15885	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BAY22_15890	COG2132	Multicopper oxidase
BAY22_15910	COG0697	spore germination
BAY22_15920	COG1049	propionate catabolic process, 2-methylcitrate cycle
BAY22_15925	COG1943	Transposase
BAY22_15930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BAY22_15935	COG0508	dehydrogenase complex catalyzes the overall conversion of
BAY22_15940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BAY22_15945	COG2186	Transcriptional regulator
BAY22_15950	COG1113	amino acid transport
BAY22_15955	COG3725	Membrane protein required for beta-lactamase induction
BAY22_15960	COG3023	N-Acetylmuramoyl-L-alanine amidase
BAY22_15970	COG4969	Belongs to the N-Me-Phe pilin family
BAY22_15975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BAY22_15980	COG1459	type II secretion system
BAY22_15995	COG0237	dephospho-CoA kinase activity
BAY22_16010	COG1943	Transposase
BAY22_16035	COG0582	viral genome integration into host DNA
BAY22_16045	COG0795	lipopolysaccharide-transporting ATPase activity
BAY22_16050	COG0795	lipopolysaccharide-transporting ATPase activity
BAY22_16060	COG2927	DNA polymerase III (CHI subunit)
BAY22_16065	COG0525	valine-tRNA ligase activity
BAY22_16075	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BAY22_16080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BAY22_16085	COG2731	YhcH YjgK YiaL family protein
BAY22_16095	COG0601	transmembrane transport
BAY22_16100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAY22_16105	COG0444	Belongs to the ABC transporter superfamily
BAY22_16110	COG4608	Belongs to the ABC transporter superfamily
BAY22_16125	COG2188	Transcriptional regulator
BAY22_16130	COG3624	Phosphonate C-P lyase system protein PhnG
BAY22_16135	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BAY22_16140	COG3626	phosphonate metabolism
BAY22_16145	COG3627	carbon phosphorus lyase activity
BAY22_16150	COG4107	phosphonate C-P lyase system protein PhnK
BAY22_16155	COG4778	phosphonate C-P lyase system protein PhnL
BAY22_16160	COG3454	Phosphonate metabolism
BAY22_16165	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BAY22_16170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BAY22_16175	COG0702	epimerase
BAY22_16190	COG3842	ATPase activity
BAY22_16195	COG0395	ABC-type sugar transport system, permease component
BAY22_16205	COG1653	transport
BAY22_16225	COG3153	acetyltransferase
BAY22_16255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BAY22_16265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BAY22_16285	COG0513	Belongs to the DEAD box helicase family
BAY22_16300	COG2801	Transposase and inactivated derivatives
BAY22_16330	COG0195	Participates in both transcription termination and antitermination
BAY22_16350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BAY22_16360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BAY22_16365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BAY22_16375	COG1534	Rna-binding protein
BAY22_16380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BAY22_16385	COG2027	D-alanyl-D-alanine carboxypeptidase
BAY22_16390	COG0745	RESPONSE REGULATOR receiver
BAY22_16395	COG0642	Histidine kinase
BAY22_16405	COG0697	spore germination
BAY22_16420	COG0142	geranyltranstransferase activity
BAY22_16430	COG3423	Transcriptional regulator
BAY22_16450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BAY22_16460	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BAY22_16465	COG2105	PFAM AIG2 family protein
BAY22_16475	COG0729	surface antigen
BAY22_16485	COG1253	flavin adenine dinucleotide binding
BAY22_16495	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BAY22_16505	COG0737	Belongs to the 5'-nucleotidase family
BAY22_16515	COG0545	Peptidyl-prolyl cis-trans isomerase
BAY22_16520	COG3061	Opacity-associated protein A
BAY22_16530	COG1943	Transposase
BAY22_16540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BAY22_16550	COG0360	Binds together with S18 to 16S ribosomal RNA
BAY22_16560	COG1073	alpha beta
BAY22_16580	COG0583	DNA-binding transcription factor activity
BAY22_16585	COG1741	Belongs to the pirin family
BAY22_16595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BAY22_16615	COG2823	Periplasmic or secreted lipoprotein
BAY22_16625	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BAY22_16635	COG2198	Histidine kinase
BAY22_16635	COG0784	Response regulator, receiver
BAY22_16635	COG5002	protein histidine kinase activity
BAY22_16645	COG1242	4 iron, 4 sulfur cluster binding
BAY22_16650	COG0070	glutamate synthase
BAY22_16650	COG0069	glutamate synthase activity
BAY22_16650	COG0067	glutamate synthase
BAY22_16655	COG0493	'glutamate synthase
BAY22_16665	COG2969	positive regulation of protein catabolic process
BAY22_16670	COG0625	glutathione transferase activity
BAY22_16690	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BAY22_16695	COG3105	Protein conserved in bacteria
BAY22_16700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BAY22_16705	COG1943	Transposase
BAY22_16710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BAY22_16720	COG5007	Belongs to the BolA IbaG family
BAY22_16725	COG3113	response to antibiotic
BAY22_16730	COG2854	intermembrane phospholipid transfer
BAY22_16735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BAY22_16740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BAY22_16745	COG1127	ABC transporter
BAY22_16750	COG0530	calcium, potassium:sodium antiporter activity
BAY22_16755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BAY22_16755	COG0517	IMP dehydrogenase activity
BAY22_16760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BAY22_16765	COG3117	lipopolysaccharide transmembrane transporter activity
BAY22_16770	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BAY22_16775	COG1137	ATPase activity
BAY22_16780	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BAY22_16790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_16800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_16835	COG1609	Transcriptional regulator
BAY22_16840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAY22_16840	COG1263	PTS System
BAY22_16845	COG0366	Alpha amylase catalytic
BAY22_16850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BAY22_16855	COG3783	Cytochrome b(562)
BAY22_16865	COG0312	modulator of DNA gyrase
BAY22_16875	COG2732	(Barnase) inhibitor
BAY22_16890	COG1012	belongs to the aldehyde dehydrogenase family
BAY22_16910	COG0583	DNA-binding transcription factor activity
BAY22_16965	COG0312	modulator of DNA gyrase
BAY22_16970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BAY22_16980	COG1530	ribonuclease E activity
BAY22_16990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BAY22_16995	COG1792	Involved in formation and maintenance of cell shape
BAY22_17000	COG1077	Cell shape determining protein MreB Mrl
BAY22_17005	COG2199	diguanylate cyclase activity
BAY22_17005	COG2200	EAL domain
BAY22_17010	COG0604	alcohol dehydrogenase
BAY22_17015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BAY22_17030	COG0511	ligase activity, forming carbon-carbon bonds
BAY22_17035	COG0439	Biotin carboxylase
BAY22_17040	COG3924	membrane
BAY22_17045	COG4145	pantothenate transmembrane transporter activity
BAY22_17055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BAY22_17060	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BAY22_17080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BAY22_17090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BAY22_17095	COG3133	Outer membrane lipoprotein
BAY22_17105	COG1278	Cold shock
BAY22_17110	COG1278	Cold shock
BAY22_17115	COG1943	Transposase
BAY22_17140	COG1069	ribulokinase activity
BAY22_17150	COG1172	Belongs to the binding-protein-dependent transport system permease family
BAY22_17155	COG1129	ABC transporter
BAY22_17165	COG1560	Kdo2-lipid A biosynthetic process
BAY22_17175	COG0025	NhaP-type Na H and K H
BAY22_17180	COG2252	PERMEase
BAY22_17185	COG3077	Addiction module antitoxin, RelB DinJ family
BAY22_17195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BAY22_17205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BAY22_17210	COG0431	NADPH-dependent FMN reductase
BAY22_17225	COG1869	D-ribose catabolic process
BAY22_17230	COG1917	Cupin 2, conserved barrel domain protein
BAY22_17230	COG2207	Transcriptional regulator
BAY22_17235	COG0673	inositol 2-dehydrogenase activity
BAY22_17250	COG3209	COG3209 Rhs family protein
BAY22_17260	COG3501	Rhs element vgr protein
BAY22_17285	COG3209	COG3209 Rhs family protein
BAY22_17300	COG3501	Rhs element vgr protein
BAY22_17445	COG1175	transmembrane transport
BAY22_17450	COG3833	ABC-type maltose transport systems, permease component
BAY22_17465	COG0527	aspartate kinase activity
BAY22_17485	COG1414	Transcriptional regulator
BAY22_17490	COG1414	Transcriptional regulator
BAY22_17500	COG2224	Isocitrate lyase
BAY22_17505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BAY22_17565	COG0151	Belongs to the GarS family
BAY22_17580	COG3068	Protein conserved in bacteria
BAY22_17585	COG1515	deoxyribonuclease V activity
BAY22_17610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BAY22_17620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BAY22_17630	COG2022	thiamine diphosphate biosynthetic process
BAY22_17645	COG1943	Transposase
BAY22_17680	COG0250	Participates in transcription elongation, termination and antitermination
BAY22_17685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BAY22_17740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BAY22_17770	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BAY22_17775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BAY22_17780	COG1739	Uncharacterized protein family UPF0029
BAY22_17785	COG1943	Transposase
BAY22_17790	COG1739	Uncharacterized protein family UPF0029
BAY22_17850	COG0805	protein transport
BAY22_17860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BAY22_17880	COG1322	Protein conserved in bacteria
BAY22_17885	COG0586	Pfam SNARE associated Golgi protein
BAY22_17890	COG1966	Carbon starvation protein
BAY22_17900	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BAY22_17905	COG0412	Dienelactone hydrolase
BAY22_17915	COG0583	DNA-binding transcription factor activity
BAY22_17925	COG0679	Auxin Efflux Carrier
BAY22_17930	COG0584	glycerophosphoryl diester phosphodiesterase
BAY22_17990	COG0410	ABC transporter
BAY22_17995	COG0411	ABC transporter
BAY22_18000	COG4177	L-phenylalanine transmembrane transporter activity
BAY22_18005	COG0559	Belongs to the binding-protein-dependent transport system permease family
BAY22_18010	COG0683	leucine binding
BAY22_18020	COG1943	Transposase
BAY22_18030	COG2177	Part of the ABC transporter FtsEX involved in
BAY22_18040	COG0552	protein localization to endoplasmic reticulum
BAY22_18040	COG0552	protein localization to endoplasmic reticulum
BAY22_18050	COG0742	ribosomal rna small subunit methyltransferase
BAY22_18055	COG3776	membrane
BAY22_18070	COG3714	YhhN family
BAY22_18085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BAY22_18095	COG0247	lactate metabolic process
BAY22_18105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BAY22_18115	COG0584	glycerophosphoryl diester phosphodiesterase
BAY22_18125	COG0561	phosphatase activity
BAY22_18130	COG2267	carboxylic ester hydrolase activity
BAY22_18135	COG1280	lysine exporter protein (LysE YggA)
BAY22_18140	COG1280	lysine exporter protein (LysE YggA)
BAY22_18145	COG0514	ATP-dependent DNA helicase (RecQ)
BAY22_18150	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BAY22_18155	COG2050	protein possibly involved in aromatic compounds catabolism
BAY22_18165	COG0598	Magnesium transport protein CorA
BAY22_18170	COG5564	TIM-barrel signal transduction protein
BAY22_18175	COG5441	Belongs to the UPF0261 family
BAY22_18185	COG0210	DNA helicase
BAY22_18190	COG1011	Hydrolase
BAY22_18195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BAY22_18200	COG3159	Protein conserved in bacteria
BAY22_18210	COG5567	small periplasmic lipoprotein
BAY22_18220	COG3072	Adenylate cyclase
BAY22_18235	COG1587	Uroporphyrinogen-III synthase
BAY22_18240	COG2959	enzyme of heme biosynthesis
BAY22_18245	COG3071	HemY protein
BAY22_18250	COG1943	Transposase
BAY22_18310	COG4143	(ABC) transporter
BAY22_18315	COG1178	ABC-type Fe3 transport system permease component
BAY22_18325	COG0586	Pfam SNARE associated Golgi protein
BAY22_18330	COG0417	DNA replication proofreading
BAY22_18350	COG3047	cAMP biosynthetic process
BAY22_18350	COG2885	chlorophyll binding
BAY22_18390	COG3501	Rhs element vgr protein
BAY22_18440	COG0564	pseudouridine synthase activity
BAY22_18445	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BAY22_18455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BAY22_18460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BAY22_18490	COG1943	Transposase
BAY22_18495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BAY22_18505	COG2966	Psort location CytoplasmicMembrane, score
BAY22_18510	COG1280	lysine exporter protein (LysE YggA)
BAY22_18515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BAY22_18520	COG0505	Belongs to the CarA family
BAY22_18530	COG1943	Transposase
BAY22_18545	COG1047	Peptidyl-prolyl cis-trans
BAY22_18560	COG0196	riboflavin kinase activity
BAY22_18575	COG0583	DNA-binding transcription factor activity
BAY22_18595	COG1584	GPR1 FUN34 yaaH family protein
BAY22_18610	COG0521	Mo-molybdopterin cofactor biosynthetic process
BAY22_18640	COG0745	RESPONSE REGULATOR receiver
BAY22_18645	COG3045	CreA protein
BAY22_18650	COG2207	Transcriptional regulator
BAY22_18650	COG3708	Transcriptional regulator
BAY22_18665	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BAY22_18670	COG0741	lytic transglycosylase activity
BAY22_18685	COG2199	diguanylate cyclase activity
BAY22_18690	COG2885	chlorophyll binding
BAY22_18715	COG0560	Phosphoserine phosphatase
BAY22_18720	COG3726	membrane protein affecting hemolysin expression
BAY22_18745	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BAY22_18750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BAY22_18755	COG0084	hydrolase, TatD family'
BAY22_18760	COG4667	esterase of the alpha-beta hydrolase superfamily
BAY22_18770	COG2823	Periplasmic or secreted lipoprotein
BAY22_18780	COG0456	acetyltransferase
BAY22_18785	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BAY22_18805	COG3706	GGDEF domain
BAY22_18830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BAY22_18835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BAY22_18855	COG0859	PFAM glycosyl transferase family 9
BAY22_18910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BAY22_18910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_18910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAY22_18915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAY22_18920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAY22_18925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAY22_18930	COG2207	Transcriptional regulator
BAY22_18940	COG4269	membrane
BAY22_18995	COG2963	transposase activity
BAY22_19010	COG1401	restriction endodeoxyribonuclease activity
BAY22_19030	COG3650	response to hydrogen peroxide
BAY22_19035	COG1960	acyl-CoA dehydrogenase activity
BAY22_19040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BAY22_19045	COG0557	exoribonuclease II activity
BAY22_19060	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BAY22_19065	COG0330	HflC and HflK could
BAY22_19070	COG0330	HflC and HflK could
BAY22_19075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BAY22_19095	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAY22_19100	COG0802	atpase or kinase
BAY22_19105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BAY22_19105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BAY22_19110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BAY22_19120	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BAY22_19140	COG1511	domain protein
BAY22_19140	COG3264	Mechanosensitive ion channel
BAY22_19155	COG1053	succinate dehydrogenase
BAY22_19160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BAY22_19170	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BAY22_19180	COG1943	Transposase
BAY22_19185	COG2076	Multidrug Resistance protein
BAY22_19240	COG3383	formate dehydrogenase (NAD+) activity
BAY22_19245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BAY22_19250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BAY22_19250	COG0493	'glutamate synthase
BAY22_19255	COG1309	transcriptional regulator
BAY22_19325	COG1454	alcohol dehydrogenase
BAY22_19335	COG0629	single-stranded DNA binding
BAY22_19340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BAY22_19345	COG2315	Protein conserved in bacteria
BAY22_19350	COG1448	Aminotransferase
BAY22_19355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BAY22_19360	COG0305	Participates in initiation and elongation during chromosome replication
BAY22_19375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BAY22_19380	COG0735	belongs to the Fur family
BAY22_19390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BAY22_19435	COG3121	Chaperone
BAY22_19450	COG1943	Transposase
BAY22_19505	COG1358	cellular component organization or biogenesis
BAY22_19530	COG3721	Heme iron utilization protein
BAY22_19535	COG0702	epimerase
BAY22_19540	COG4771	TonB-dependent receptor
BAY22_19545	COG3720	iron ion transport
BAY22_19550	COG4558	Periplasmic binding protein
BAY22_19555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BAY22_19570	COG0814	amino acid
BAY22_19575	COG0583	DNA-binding transcription factor activity
BAY22_19580	COG0425	Belongs to the sulfur carrier protein TusA family
BAY22_19585	COG2391	methyltransferase activity
BAY22_19695	COG1301	dicarboxylic acid transport
BAY22_19705	COG3162	membrane
BAY22_19730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BAY22_19745	COG0551	DNA topoisomerase type I activity
BAY22_19755	COG0758	DNA mediated transformation
BAY22_19775	COG0569	domain protein
BAY22_19785	COG3036	rescue of stalled ribosome
BAY22_19790	COG0789	Transcriptional regulator
BAY22_19805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BAY22_19820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BAY22_19825	COG0201	protein transport
BAY22_19835	COG1841	ribosomal large subunit assembly
BAY22_19875	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BAY22_19880	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BAY22_19890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BAY22_19895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BAY22_19905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BAY22_19930	COG0051	transcription antitermination factor activity, RNA binding
BAY22_19945	COG1943	Transposase
BAY22_19960	COG0049	tRNA binding
BAY22_19965	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BAY22_19985	COG2964	Protein conserved in bacteria
BAY22_19990	COG0545	Peptidyl-prolyl cis-trans isomerase
BAY22_20000	COG1047	Peptidyl-prolyl cis-trans
BAY22_20005	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BAY22_20025	COG1216	Glycosyl transferase, family 2
BAY22_20035	COG2175	clavaminate synthase activity
BAY22_20040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BAY22_20050	COG4521	taurine ABC transporter
BAY22_20060	COG0429	hydrolase of the alpha beta-hydrolase fold
BAY22_20070	COG3954	Phosphoribulokinase
BAY22_20080	COG1765	OsmC-like protein
BAY22_20090	COG1289	transmembrane transporter activity
BAY22_20120	COG0433	COG0433 Predicted ATPase
BAY22_20125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BAY22_20130	COG1486	melibiose metabolic process
BAY22_20150	COG0402	S-adenosylhomocysteine deaminase activity
BAY22_20155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BAY22_20160	COG2146	nitrite reductase [NAD(P)H] activity
BAY22_20175	COG0180	Tryptophanyl-tRNA synthetase
BAY22_20180	COG0546	phosphoglycolate phosphatase activity
BAY22_20185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BAY22_20210	COG4796	Type ii and iii secretion system protein
BAY22_20240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BAY22_20245	COG0494	nUDIX hydrolase
BAY22_20260	COG1011	Hydrolase
BAY22_20265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BAY22_20285	COG0745	RESPONSE REGULATOR receiver
BAY22_20290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BAY22_20295	COG2183	response to ionizing radiation
BAY22_20305	COG1918	ferrous iron import across plasma membrane
BAY22_20340	COG1640	4-alpha-glucanotransferase
BAY22_20345	COG0058	SHG alpha-glucan phosphorylase activity
BAY22_20350	COG0058	SHG alpha-glucan phosphorylase activity
BAY22_20360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BAY22_20370	COG1349	DNA-binding transcription factor activity
BAY22_20380	COG2801	Transposase and inactivated derivatives
BAY22_20390	COG0460	homoserine dehydrogenase
BAY22_20390	COG0527	aspartate kinase activity
BAY22_20410	COG4682	membrane
BAY22_20420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BAY22_20430	COG1609	Transcriptional regulator
BAY22_20435	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BAY22_20450	COG1575	Belongs to the MenA family. Type 1 subfamily
BAY22_20500	COG1943	Transposase
BAY22_20515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BAY22_20535	COG3152	Membrane
BAY22_20550	COG0583	DNA-binding transcription factor activity
BAY22_20555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BAY22_20560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BAY22_20565	COG0471	metal ion transport
BAY22_20575	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BAY22_20595	COG3678	ATP-independent chaperone mediated protein folding
BAY22_20600	COG0745	RESPONSE REGULATOR receiver
BAY22_20605	COG2205	protein histidine kinase activity
BAY22_20610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BAY22_20610	COG2169	Transcriptional regulator
BAY22_20615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BAY22_20620	COG1045	serine acetyltransferase
BAY22_20640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BAY22_20645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BAY22_20655	COG4942	peptidase
BAY22_20670	COG0156	8-amino-7-oxononanoate synthase activity
BAY22_20680	COG0859	PFAM glycosyl transferase family 9
BAY22_20685	COG0859	PFAM glycosyl transferase family 9
BAY22_20690	COG1519	Transferase
BAY22_20710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BAY22_20725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BAY22_20750	COG1561	YicC-like family, N-terminal region
BAY22_20755	COG2860	membrane
BAY22_20760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BAY22_20775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BAY22_20780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BAY22_20785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BAY22_20790	COG0786	glutamate:sodium symporter activity
BAY22_20795	COG2233	PERMEase
BAY22_20800	COG2982	Protein involved in outer membrane biogenesis
BAY22_20805	COG0456	acetyltransferase
BAY22_20825	COG1295	ribonuclease BN
BAY22_20830	COG1011	Hydrolase
BAY22_20845	COG0174	glutamine synthetase
BAY22_20850	COG3852	Histidine kinase
BAY22_20875	COG1943	Transposase
BAY22_20880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BAY22_20880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BAY22_20885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BAY22_20890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BAY22_20895	COG3084	Protein conserved in bacteria
BAY22_20905	COG1763	Mo-molybdopterin cofactor biosynthetic process
BAY22_20910	COG3328	transposase activity
BAY22_20940	COG2186	Transcriptional regulator
BAY22_20945	COG0477	Major facilitator Superfamily
BAY22_20955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAY22_20985	COG1522	sequence-specific DNA binding
BAY22_20990	COG0716	FMN binding
BAY22_21005	COG3312	ion transport
BAY22_21055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BAY22_21060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BAY22_21065	COG0573	inorganic phosphate transmembrane transporter activity
BAY22_21070	COG0581	inorganic phosphate transmembrane transporter activity
BAY22_21080	COG0704	Plays a role in the regulation of phosphate uptake
BAY22_21090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAY22_21095	COG0765	amino acid transport
BAY22_21100	COG0765	amino acid transport
BAY22_21105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BAY22_21110	COG2252	PERMEase
BAY22_21135	COG0706	membrane insertase activity
BAY22_21145	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BAY22_21155	COG0592	DNA-directed DNA polymerase activity
BAY22_21165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BAY22_21170	COG0187	DNA topoisomerase II activity
BAY22_21175	COG0561	phosphatase activity
BAY22_21180	COG2801	Transposase and inactivated derivatives
BAY22_21190	COG2423	ornithine cyclodeaminase activity
BAY22_21195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BAY22_21200	COG0823	Involved in the tonB-independent uptake of proteins
BAY22_21205	COG0823	Involved in the tonB-independent uptake of proteins
BAY22_21210	COG5645	(Lipo)protein
BAY22_21230	COG3977	Valine--pyruvate aminotransferase
BAY22_21280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BAY22_21285	COG4790	Type iii secretion
BAY22_21290	COG4794	Type iii secretion
BAY22_21295	COG4791	protein targeting
BAY22_21300	COG4792	protein secretion
BAY22_21310	COG2207	Transcriptional regulator
BAY22_21360	COG4669	(LipO)protein
BAY22_21370	COG1317	bacterial-type flagellum organization
BAY22_21375	COG5599	Phosphatase
BAY22_21380	COG2963	transposase activity
BAY22_21385	COG2801	Transposase and inactivated derivatives
BAY22_21400	COG4372	Transposase
BAY22_21405	COG2801	Transposase and inactivated derivatives
BAY22_21415	COG0515	serine threonine protein kinase
BAY22_21485	COG2801	Transposase and inactivated derivatives
BAY22_21515	COG2801	Transposase and inactivated derivatives
BAY22_21550	COG2801	Transposase and inactivated derivatives
BAY22_21560	COG5599	Phosphatase
BAY22_21570	COG3609	addiction module antidote protein, CC2985 family
BAY22_21580	COG1475	DNA binding
BAY22_21585	COG1192	Involved in chromosome partitioning
BAY22_21595	COG2801	Transposase and inactivated derivatives
BAY22_21615	COG3177	Filamentation induced by cAMP protein fic
BAY22_21640	COG4886	Leucine-rich repeat (LRR) protein
BAY22_21660	COG0457	Tetratricopeptide repeat
BAY22_21680	COG4789	Type iii secretion
BAY22_21715	COG3328	transposase activity
BAY22_21755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BAY22_21835	COG1475	DNA binding
BAY22_21880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BAY22_21890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BAY22_21950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BAY22_21985	COG1943	Transposase
BAY22_22035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BAY22_22040	COG1475	DNA binding
BAY22_22045	COG1475	DNA binding
BAY22_22140	COG3941	tape measure
BAY22_22175	COG5301	cellulose 1,4-beta-cellobiosidase activity
BAY22_22175	COG5301	cellulose 1,4-beta-cellobiosidase activity
BAY22_22185	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BAY22_22250	COG4683	PFAM Phage derived protein Gp49-like (DUF891)