locus-tag	class	description
CH61_10	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH61_1005	COG2824	Alkylphosphonate utilization operon protein PhnA
CH61_1007	COG1704	LemA family
CH61_1011	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH61_1012	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH61_1013	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH61_1015	COG1138	Cytochrome C-type biogenesis protein
CH61_1016	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH61_1017	COG4235	cytochrome complex assembly
CH61_1017	COG3088	subunit of a heme lyase
CH61_1018	COG3088	subunit of a heme lyase
CH61_1018	COG4235	cytochrome complex assembly
CH61_1021	COG3691	Protein conserved in bacteria
CH61_1024	COG2062	phosphohistidine phosphatase, SixA
CH61_1026	COG2890	protein-(glutamine-N5) methyltransferase activity
CH61_1028	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CH61_1029	COG0730	response to heat
CH61_103	COG2271	Major facilitator Superfamily
CH61_1030	COG3101	peptidyl-lysine hydroxylation
CH61_1033	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_1034	COG1794	racemase activity, acting on amino acids and derivatives
CH61_1037	COG0697	spore germination
CH61_1040	COG1943	Transposase
CH61_1042	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH61_1044	COG0586	Pfam SNARE associated Golgi protein
CH61_1046	COG0285	dihydrofolate synthase activity
CH61_1047	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH61_1048	COG1286	toxin biosynthetic process
CH61_1049	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH61_1050	COG0163	prenyltransferase activity
CH61_1051	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_1052	COG4215	(ABC) transporter
CH61_1053	COG4160	amino acid transport
CH61_1054	COG4598	ABC transporter
CH61_1055	COG1090	epimerase
CH61_1057	COG0622	Phosphoesterase
CH61_1058	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH61_1059	COG3037	sugar-specific permease SgaT UlaA
CH61_1060	COG3328	transposase activity
CH61_1061	COG4953	penicillin-binding protein 1C
CH61_1062	COG3423	Transcriptional regulator
CH61_107	COG2831	hemolysin activation secretion protein
CH61_1072	COG2850	peptidyl-arginine hydroxylation
CH61_1073	COG3328	transposase activity
CH61_1078	COG0656	L-ascorbic acid biosynthetic process
CH61_1079	COG0667	Aldo Keto reductase
CH61_1086	COG2453	phosphatase
CH61_1086	COG0671	phosphoesterase, PA-phosphatase related
CH61_1087	COG2267	carboxylic ester hydrolase activity
CH61_1089	COG4589	Belongs to the CDS family
CH61_109	COG0747	negative chemotaxis
CH61_1090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH61_1098	COG2501	S4 domain
CH61_11	COG0187	DNA topoisomerase II activity
CH61_110	COG0601	transmembrane transport
CH61_1102	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH61_1103	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH61_1107	COG0581	inorganic phosphate transmembrane transporter activity
CH61_1109	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH61_111	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_1110	COG0248	Ppx GppA phosphatase
CH61_1111	COG2239	Acts as a magnesium transporter
CH61_1112	COG0443	Heat shock 70 kDa protein
CH61_1113	COG1177	transmembrane transport
CH61_1114	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH61_1116	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH61_1118	COG3842	ATPase activity
CH61_112	COG0444	Belongs to the ABC transporter superfamily
CH61_1123	COG2205	protein histidine kinase activity
CH61_1124	COG0745	RESPONSE REGULATOR receiver
CH61_1125	COG3422	double-strand break repair
CH61_113	COG4608	Belongs to the ABC transporter superfamily
CH61_1131	COG0351	phosphomethylpyrimidine kinase
CH61_1134	COG3328	transposase activity
CH61_114	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH61_1141	COG1943	Transposase
CH61_1143	COG0516	GMP reductase activity
CH61_1143	COG0517	IMP dehydrogenase activity
CH61_1145	COG1645	bacterial-type flagellum-dependent swarming motility
CH61_1148	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH61_1149	COG2976	Protein conserved in bacteria
CH61_115	COG2200	EAL domain
CH61_115	COG2199	diguanylate cyclase activity
CH61_1157	COG3468	outer membrane autotransporter barrel domain protein
CH61_1158	COG3468	outer membrane autotransporter barrel domain protein
CH61_116	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH61_1162	COG2975	iron-sulfur cluster assembly
CH61_1163	COG0633	Ferredoxin
CH61_1164	COG0443	Heat shock 70 kDa protein
CH61_1167	COG0822	iron-sulfur transferase activity
CH61_1168	COG1104	cysteine desulfurase activity
CH61_1171	COG0483	inositol monophosphate 1-phosphatase activity
CH61_1172	COG1943	Transposase
CH61_1173	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH61_1174	COG3683	transport system, periplasmic component
CH61_1175	COG2814	Major facilitator Superfamily
CH61_1176	COG3711	transcriptional antiterminator
CH61_1179	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_1179	COG1017	nitric oxide dioxygenase activity
CH61_1182	COG0347	Belongs to the P(II) protein family
CH61_1183	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH61_1183	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH61_1184	COG2204	response regulator
CH61_1185	COG3170	Tfp pilus assembly protein FimV
CH61_1186	COG2205	protein histidine kinase activity
CH61_1192	COG0590	tRNA wobble adenosine to inosine editing
CH61_1193	COG0560	Phosphoserine phosphatase
CH61_1195	COG1737	Transcriptional regulator
CH61_1196	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_1197	COG1943	Transposase
CH61_1199	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH61_12	COG0561	phosphatase activity
CH61_1209	COG3188	usher protein
CH61_121	COG0612	Peptidase, M16
CH61_1210	COG3328	transposase activity
CH61_1211	COG3188	usher protein
CH61_1212	COG3121	Chaperone
CH61_122	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_1224	COG2951	lytic endotransglycosylase activity
CH61_123	COG1942	4-Oxalocrotonate Tautomerase
CH61_1231	COG0243	molybdopterin cofactor binding
CH61_1232	COG0437	4 iron, 4 sulfur cluster binding
CH61_1233	COG3302	dmso reductase anchor subunit
CH61_1234	COG3381	protein complex oligomerization
CH61_124	COG2200	EAL domain
CH61_1240	COG3038	cytochrome b561
CH61_1241	COG0436	Aminotransferase
CH61_1246	COG0667	Aldo Keto reductase
CH61_1249	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH61_125	COG2134	cdp-diacylglycerol pyrophosphatase
CH61_1255	COG1943	Transposase
CH61_126	COG2982	Protein involved in outer membrane biogenesis
CH61_1261	COG3530	Putative quorum-sensing-regulated virulence factor
CH61_1264	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH61_1265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH61_1266	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_1268	COG2190	(PTS) system
CH61_1269	COG1943	Transposase
CH61_127	COG1295	ribonuclease BN
CH61_1271	COG2205	protein histidine kinase activity
CH61_1272	COG0745	RESPONSE REGULATOR receiver
CH61_1273	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_1276	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH61_1278	COG0006	proline dipeptidase activity
CH61_1280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH61_1282	COG5002	protein histidine kinase activity
CH61_1282	COG3850	Histidine kinase
CH61_1283	COG0745	RESPONSE REGULATOR receiver
CH61_1286	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH61_1287	COG4208	sulfate ABC transporter
CH61_1288	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH61_1289	COG4150	thiosulfate binding
CH61_1291	COG1737	Transcriptional regulator
CH61_1292	COG2731	YhcH YjgK YiaL family protein
CH61_1294	COG4886	Leucine-rich repeat (LRR) protein
CH61_1296	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH61_1297	COG2837	iron assimilation
CH61_1299	COG3111	PFAM Bacterial OB fold (BOF) protein
CH61_13	COG2801	Transposase and inactivated derivatives
CH61_1308	COG3005	denitrification pathway
CH61_1309	COG3043	anaerobic respiration
CH61_1311	COG3062	negative regulation of establishment of protein localization
CH61_1312	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_1312	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_1313	COG2197	response regulator
CH61_1315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_1317	COG1988	membrane-bound metal-dependent
CH61_1318	COG0641	radical SAM
CH61_1319	COG3119	arylsulfatase activity
CH61_132	COG1929	Belongs to the glycerate kinase type-1 family
CH61_1320	COG3842	ATPase activity
CH61_1321	COG1175	transmembrane transport
CH61_1322	COG1840	ABC-type Fe3 transport system, periplasmic component
CH61_1324	COG1393	Belongs to the ArsC family
CH61_1326	COG1876	peptidase activity
CH61_133	COG2610	gluconate transmembrane transporter activity
CH61_1330	COG2321	neutral zinc metallopeptidase
CH61_1332	COG1943	Transposase
CH61_1333	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH61_1335	COG2716	regulation of RNA biosynthetic process
CH61_1336	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH61_1339	COG0628	permease
CH61_134	COG3835	regulator
CH61_1340	COG4783	chaperone-mediated protein folding
CH61_1341	COG1393	Belongs to the ArsC family
CH61_1343	COG1943	Transposase
CH61_1347	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH61_1349	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH61_135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH61_1350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH61_1351	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH61_1352	COG4181	ATPase activity
CH61_1353	COG2755	lipolytic protein G-D-S-L family
CH61_1354	COG0300	oxidoreductase activity
CH61_1355	COG3118	belongs to the thioredoxin family
CH61_1356	COG0330	HflC and HflK could
CH61_1357	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH61_1358	COG0789	Transcriptional regulator
CH61_1359	COG2217	Heavy metal translocating P-type atpase
CH61_136	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH61_1360	COG3735	TraB family
CH61_1361	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH61_1364	COG0737	Belongs to the 5'-nucleotidase family
CH61_1365	COG0737	Belongs to the 5'-nucleotidase family
CH61_1366	COG0737	Belongs to the 5'-nucleotidase family
CH61_1367	COG2223	nitrite transmembrane transporter activity
CH61_1368	COG4651	solute:proton antiporter activity
CH61_1368	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH61_1369	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_137	COG0339	signal peptide processing
CH61_1370	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH61_1376	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH61_1377	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH61_1386	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_1390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_1390	COG0543	2 iron, 2 sulfur cluster binding
CH61_1396	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH61_1403	COG2832	Protein of unknown function (DUF454)
CH61_1406	COG1196	nuclear chromosome segregation
CH61_1406	COG3264	Mechanosensitive ion channel
CH61_1407	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH61_1408	COG1309	transcriptional regulator
CH61_1409	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_141	COG0589	response to stress
CH61_1410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_1412	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH61_1416	COG3695	enzyme binding
CH61_1417	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH61_1418	COG1946	Acyl-CoA thioesterase
CH61_1419	COG0004	ammonium transporteR
CH61_1420	COG0347	Belongs to the P(II) protein family
CH61_1421	COG1132	(ABC) transporter
CH61_1422	COG1132	(ABC) transporter
CH61_1423	COG1522	sequence-specific DNA binding
CH61_1426	COG4533	DNA binding
CH61_1428	COG0824	Thioesterase
CH61_1429	COG1555	photosystem II stabilization
CH61_143	COG1943	Transposase
CH61_1430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH61_1431	COG0776	regulation of translation
CH61_1432	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH61_1437	COG0271	Belongs to the BolA IbaG family
CH61_1438	COG3056	Lipoprotein
CH61_1439	COG2223	nitrite transmembrane transporter activity
CH61_144	COG0306	phosphate transporter
CH61_1441	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH61_1442	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH61_1443	COG1845	cytochrome c oxidase, subunit III
CH61_1444	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH61_1446	COG2814	Major facilitator Superfamily
CH61_1448	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH61_1449	COG0693	protein deglycase activity
CH61_145	COG2081	HI0933 family
CH61_1452	COG0142	geranyltranstransferase activity
CH61_1454	COG1943	Transposase
CH61_1455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH61_1456	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH61_1459	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH61_1459	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH61_1463	COG1943	Transposase
CH61_1464	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH61_1465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH61_1466	COG1862	Preprotein translocase
CH61_1468	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CH61_1469	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CH61_1470	COG0450	alkyl hydroperoxide reductase
CH61_1471	COG1943	Transposase
CH61_1475	COG0366	Alpha amylase catalytic
CH61_1477	COG1114	Component of the transport system for branched-chain amino acids
CH61_1479	COG5002	protein histidine kinase activity
CH61_148	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_1480	COG0745	RESPONSE REGULATOR receiver
CH61_1481	COG0420	3'-5' exonuclease activity
CH61_1482	COG0419	ATPase involved in DNA repair
CH61_1486	COG1940	carbohydrate kinase activity
CH61_149	COG1879	ABC-type sugar transport system periplasmic component
CH61_1491	COG2226	methyltransferase
CH61_1502	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH61_1506	COG1477	protein flavinylation
CH61_151	COG0191	fructose-bisphosphate aldolase activity
CH61_1510	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH61_1511	COG1805	sodium ion transport
CH61_1512	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH61_1513	COG0121	glutamine amidotransferase
CH61_1514	COG3034	peptidoglycan biosynthetic process
CH61_1516	COG1960	acyl-CoA dehydrogenase activity
CH61_1518	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH61_1522	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH61_1526	COG0582	viral genome integration into host DNA
CH61_1527	COG2963	transposase activity
CH61_1529	COG0596	Alpha beta hydrolase
CH61_153	COG0745	RESPONSE REGULATOR receiver
CH61_1533	COG0735	belongs to the Fur family
CH61_1538	COG1943	Transposase
CH61_1539	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_1539	COG2190	(PTS) system
CH61_1539	COG1263	PTS System
CH61_1541	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH61_1542	COG1940	carbohydrate kinase activity
CH61_1542	COG1846	Transcriptional regulator
CH61_1543	COG0647	UMP catabolic process
CH61_1544	COG0367	asparagine synthase
CH61_155	COG1741	Belongs to the pirin family
CH61_1550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH61_1552	COG1702	phosphate starvation-inducible protein PhoH
CH61_1554	COG4535	Mg2 and Co2 transporter CorC
CH61_1555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH61_1557	COG0765	amino acid transport
CH61_1558	COG0765	amino acid transport
CH61_1559	COG1126	abc transporter atp-binding protein
CH61_156	COG1609	Transcriptional regulator
CH61_1560	COG2888	peptidyl-tyrosine sulfation
CH61_1563	COG1466	dna polymerase III delta subunit
CH61_1565	COG0799	negative regulation of ribosome biogenesis
CH61_1567	COG0768	penicillin binding
CH61_1568	COG0772	Belongs to the SEDS family
CH61_1569	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH61_157	COG2610	gluconate transmembrane transporter activity
CH61_1570	COG1686	Belongs to the peptidase S11 family
CH61_1574	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH61_1575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH61_1576	COG1278	Cold shock
CH61_1578	COG2197	response regulator
CH61_158	COG3265	gluconokinase activity
CH61_1583	COG5265	(ABC) transporter
CH61_1585	COG3718	enzyme involved in inositol metabolism
CH61_1587	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_1588	COG0673	inositol 2-dehydrogenase activity
CH61_1589	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_1590	COG1129	ABC transporter
CH61_1591	COG1879	ABC-type sugar transport system periplasmic component
CH61_1592	COG0673	inositol 2-dehydrogenase activity
CH61_1593	COG0673	inositol 2-dehydrogenase activity
CH61_1594	COG3962	Belongs to the TPP enzyme family
CH61_16	COG2423	ornithine cyclodeaminase activity
CH61_1600	COG2373	Large extracellular alpha-helical protein
CH61_1601	COG4953	penicillin-binding protein 1C
CH61_1602	COG3328	transposase activity
CH61_1605	COG1609	Transcriptional regulator
CH61_1606	COG0857	belongs to the CobB CobQ family
CH61_1606	COG0280	phosphate acetyltransferase
CH61_1610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_1611	COG0471	metal ion transport
CH61_1611	COG0490	domain, Protein
CH61_1613	COG0436	Aminotransferase
CH61_1614	COG0583	DNA-binding transcription factor activity
CH61_1616	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH61_1618	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CH61_162	COG2095	MarC family integral membrane protein
CH61_1620	COG1034	ATP synthesis coupled electron transport
CH61_1623	COG0839	Belongs to the complex I subunit 6 family
CH61_1625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH61_1626	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH61_1629	COG2731	YhcH YjgK YiaL family protein
CH61_163	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH61_1630	COG3265	gluconokinase activity
CH61_1631	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_1633	COG1609	Transcriptional regulator
CH61_1634	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH61_1637	COG0129	dihydroxy-acid dehydratase activity
CH61_1639	COG4575	ribosome binding
CH61_1641	COG1169	isochorismate synthase
CH61_1644	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH61_1647	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH61_1653	COG1126	abc transporter atp-binding protein
CH61_1654	COG0765	amino acid transport
CH61_1655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_1661	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH61_1665	COG1063	alcohol dehydrogenase
CH61_1666	COG1879	ABC-type sugar transport system periplasmic component
CH61_1667	COG1129	ABC transporter
CH61_1668	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_1669	COG1609	Transcriptional regulator
CH61_1670	COG0583	DNA-binding transcription factor activity
CH61_1671	COG0473	3-isopropylmalate dehydrogenase activity
CH61_1672	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH61_1673	COG4638	Rieske (2fe-2S)
CH61_1674	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_1675	COG2831	hemolysin activation secretion protein
CH61_1676	COG3210	domain, Protein
CH61_1679	COG3210	domain, Protein
CH61_1682	COG3210	domain, Protein
CH61_1684	COG3842	ATPase activity
CH61_1686	COG1609	Transcriptional regulator
CH61_1689	COG0395	ABC-type sugar transport system, permease component
CH61_169	COG3275	phosphorelay sensor kinase activity
CH61_1690	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH61_1694	COG0668	transmembrane transport
CH61_1695	COG1518	maintenance of DNA repeat elements
CH61_1696	COG1203	CRISPR-associated helicase, Cas3
CH61_17	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH61_1701	COG0667	Aldo Keto reductase
CH61_1703	COG0477	Major facilitator Superfamily
CH61_1705	COG0583	DNA-binding transcription factor activity
CH61_1706	COG3916	Acyl-homoserine-lactone synthase
CH61_1707	COG2771	luxR family
CH61_1711	COG0628	permease
CH61_1714	COG3328	transposase activity
CH61_1715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_1718	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH61_1719	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH61_172	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CH61_1720	COG1121	(ABC) transporter
CH61_1721	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH61_1725	COG4249	Peptidase C14 caspase catalytic subunit p20
CH61_1730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH61_1731	COG0072	phenylalanine-tRNA ligase activity
CH61_1731	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH61_1732	COG0776	regulation of translation
CH61_1735	COG0386	Belongs to the glutathione peroxidase family
CH61_1736	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CH61_174	COG0058	SHG alpha-glucan phosphorylase activity
CH61_1744	COG0791	NLP P60 protein
CH61_175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH61_1750	COG0574	Belongs to the PEP-utilizing enzyme family
CH61_1750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH61_1751	COG0628	permease
CH61_1752	COG0247	lactate metabolic process
CH61_1752	COG0277	FAD linked oxidase domain protein
CH61_1753	COG2050	protein possibly involved in aromatic compounds catabolism
CH61_1754	COG0316	Belongs to the HesB IscA family
CH61_1755	COG0719	Fe-S assembly protein
CH61_1756	COG0396	ATPase activity
CH61_1757	COG0719	Fe-S assembly protein
CH61_1760	COG1376	ErfK ybiS ycfS ynhG family protein
CH61_1760	COG1388	LysM domain
CH61_1764	COG1943	Transposase
CH61_1765	COG4238	major outer membrane lipoprotein
CH61_1770	COG0307	riboflavin synthase, alpha
CH61_1771	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH61_1772	COG2814	Major facilitator Superfamily
CH61_1773	COG0583	DNA-binding transcription factor activity
CH61_1776	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH61_1777	COG0791	NLP P60 protein
CH61_1779	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH61_178	COG2801	Transposase and inactivated derivatives
CH61_1780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH61_1781	COG0346	lactoylglutathione lyase activity
CH61_1783	COG1902	pentaerythritol trinitrate reductase activity
CH61_1784	COG1309	transcriptional regulator
CH61_1785	COG2194	sulfuric ester hydrolase activity
CH61_1786	COG3313	Fe-S protein
CH61_1787	COG4989	oxidoreductase activity
CH61_1789	COG3133	Outer membrane lipoprotein
CH61_1791	COG3895	Periplasmic Protein
CH61_1795	COG0625	glutathione transferase activity
CH61_18	COG0823	Involved in the tonB-independent uptake of proteins
CH61_1800	COG3104	oligopeptide transport
CH61_1802	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH61_1802	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH61_1803	COG4172	Belongs to the ABC transporter superfamily
CH61_1805	COG4171	peptide transport system, permease
CH61_1806	COG4168	peptide transport system, permease
CH61_1807	COG4166	transmembrane transport
CH61_1808	COG1943	Transposase
CH61_1809	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH61_1810	COG1842	Phage shock protein A
CH61_1812	COG1983	PspC domain protein
CH61_1814	COG3106	COG3106 Predicted ATPase
CH61_1819	COG1943	Transposase
CH61_1820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH61_1821	COG4948	Mandelate Racemase Muconate Lactonizing
CH61_1822	COG2866	Carboxypeptidase
CH61_1823	COG4166	transmembrane transport
CH61_1826	COG0657	acetylesterase activity
CH61_1826	COG2755	lipolytic protein G-D-S-L family
CH61_1829	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH61_1829	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH61_1829	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH61_1829	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH61_1831	COG1285	pathogenesis
CH61_1832	COG3042	response to heat
CH61_1833	COG3187	Heat shock protein
CH61_1834	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH61_1835	COG2911	Protein conserved in bacteria
CH61_1837	COG3784	Protein of unknown function (DUF1318)
CH61_1838	COG0246	Mannitol dehydrogenase
CH61_1839	COG2390	Transcriptional regulator
CH61_1841	COG1643	Atp-dependent helicase
CH61_1844	COG3591	Belongs to the peptidase S1B family
CH61_1846	COG3038	cytochrome b561
CH61_185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH61_1850	COG1943	Transposase
CH61_1851	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH61_1852	COG2205	protein histidine kinase activity
CH61_1853	COG0745	RESPONSE REGULATOR receiver
CH61_1855	COG0531	amino acid
CH61_1857	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH61_1858	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH61_1859	COG0589	response to stress
CH61_1860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH61_1861	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH61_1865	COG1011	Hydrolase
CH61_1866	COG0440	acetolactate synthase activity
CH61_1867	COG0028	Belongs to the TPP enzyme family
CH61_1872	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH61_1873	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH61_1874	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH61_1875	COG1879	ABC-type sugar transport system periplasmic component
CH61_1877	COG1609	Transcriptional regulator
CH61_1881	COG4128	Pfam Zonular occludens toxin
CH61_189	COG1629	transport
CH61_1891	COG0038	chloride channel
CH61_1892	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH61_1894	COG1940	carbohydrate kinase activity
CH61_1895	COG0583	DNA-binding transcription factor activity
CH61_1896	COG2814	Major facilitator Superfamily
CH61_1898	COG0114	fumarate hydratase activity
CH61_19	COG0823	Involved in the tonB-independent uptake of proteins
CH61_1900	COG5339	Protein conserved in bacteria
CH61_1902	COG0385	Bile acid
CH61_1903	COG0673	inositol 2-dehydrogenase activity
CH61_1905	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_1907	COG1879	ABC-type sugar transport system periplasmic component
CH61_1911	COG2274	protein secretion by the type I secretion system
CH61_1912	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_1919	COG2207	Transcriptional regulator
CH61_1919	COG3708	Transcriptional regulator
CH61_1920	COG4658	electron transport chain
CH61_1921	COG4659	FMN binding
CH61_1923	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH61_1924	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_1925	COG2271	Major facilitator Superfamily
CH61_1927	COG1966	Carbon starvation protein
CH61_1928	COG2879	small protein
CH61_1929	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH61_1933	COG0023	Translation Initiation Factor
CH61_1936	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH61_1937	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH61_1938	COG0671	phosphoesterase, PA-phosphatase related
CH61_1939	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH61_194	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH61_1940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH61_1942	COG0583	DNA-binding transcription factor activity
CH61_1943	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH61_1946	COG0616	signal peptide processing
CH61_1947	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_1949	COG1187	pseudouridine synthase activity
CH61_195	COG0678	peroxiredoxin activity
CH61_195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH61_1950	COG0009	L-threonylcarbamoyladenylate synthase
CH61_1953	COG0512	Glutamine amidotransferase of anthranilate synthase
CH61_1955	COG0135	phosphoribosylanthranilate isomerase activity
CH61_1955	COG0134	indole-3-glycerol-phosphate synthase activity
CH61_1959	COG3047	cAMP biosynthetic process
CH61_1964	COG1607	acyl-coa hydrolase
CH61_1965	COG3328	transposase activity
CH61_1966	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH61_1967	COG2350	Protein conserved in bacteria
CH61_1974	COG4608	Belongs to the ABC transporter superfamily
CH61_1975	COG0444	Belongs to the ABC transporter superfamily
CH61_1976	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_1977	COG0601	transmembrane transport
CH61_1979	COG2095	MarC family integral membrane protein
CH61_1980	COG1012	belongs to the aldehyde dehydrogenase family
CH61_1980	COG1454	alcohol dehydrogenase
CH61_1983	COG1435	thymidine kinase activity
CH61_1986	COG0745	RESPONSE REGULATOR receiver
CH61_1988	COG3328	transposase activity
CH61_1989	COG0788	formyltetrahydrofolate deformylase activity
CH61_1990	COG3328	transposase activity
CH61_1993	COG0583	DNA-binding transcription factor activity
CH61_1994	COG0708	Exodeoxyribonuclease III
CH61_1995	COG0494	nUDIX hydrolase
CH61_1997	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH61_1998	COG0709	Synthesizes selenophosphate from selenide and ATP
CH61_1999	COG0778	Nitroreductase
CH61_20	COG5645	(Lipo)protein
CH61_2000	COG0616	signal peptide processing
CH61_2001	COG0252	asparaginase activity
CH61_2002	COG1335	isochorismatase
CH61_2003	COG3139	Protein of unknown function (DUF1315)
CH61_2007	COG3713	MltA-interacting MipA family protein
CH61_2008	COG2766	serine protein kinase
CH61_2011	COG0583	DNA-binding transcription factor activity
CH61_2013	COG2814	Major facilitator Superfamily
CH61_2015	COG2719	SpoVR family
CH61_2021	COG1104	cysteine desulfurase activity
CH61_2023	COG3328	transposase activity
CH61_2039	COG1943	Transposase
CH61_2056	COG3328	transposase activity
CH61_2077	COG0582	viral genome integration into host DNA
CH61_2079	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH61_2080	COG2951	lytic endotransglycosylase activity
CH61_2083	COG2894	cell division
CH61_2084	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH61_2085	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH61_2086	COG0318	PFAM AMP-dependent synthetase and ligase
CH61_2087	COG3065	identical protein binding
CH61_2089	COG1199	ATP-dependent helicase activity
CH61_2090	COG0251	oxidation-reduction process
CH61_2093	COG0800	Aldolase
CH61_2095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH61_2096	COG1737	Transcriptional regulator
CH61_2097	COG0469	pyruvate kinase activity
CH61_2098	COG1560	Kdo2-lipid A biosynthetic process
CH61_2099	COG0739	heme binding
CH61_210	COG1879	ABC-type sugar transport system periplasmic component
CH61_2100	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH61_2102	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH61_2107	COG0494	nUDIX hydrolase
CH61_2109	COG1801	Protein of unknown function DUF72
CH61_211	COG1129	ABC transporter
CH61_2110	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH61_2114	COG3102	Protein conserved in bacteria
CH61_2118	COG0728	peptidoglycan biosynthetic process
CH61_2119	COG0673	inositol 2-dehydrogenase activity
CH61_212	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_2120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH61_2123	COG3381	protein complex oligomerization
CH61_2126	COG1940	carbohydrate kinase activity
CH61_2127	COG0584	glycerophosphoryl diester phosphodiesterase
CH61_2128	COG3842	ATPase activity
CH61_2129	COG1943	Transposase
CH61_2131	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH61_2132	COG3833	ABC-type maltose transport systems, permease component
CH61_2136	COG0659	secondary active sulfate transmembrane transporter activity
CH61_2139	COG0659	secondary active sulfate transmembrane transporter activity
CH61_214	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_2140	COG1943	Transposase
CH61_2142	COG2912	Transglutaminase-like superfamily
CH61_2143	COG3094	Invasion gene expression up-regulator, SirB
CH61_2144	COG2890	protein-(glutamine-N5) methyltransferase activity
CH61_2149	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH61_215	COG3085	chromosome segregation
CH61_2152	COG0012	GTP binding
CH61_2163	COG5002	protein histidine kinase activity
CH61_2172	COG0500	methyltransferase
CH61_2177	COG3328	transposase activity
CH61_218	COG3978	acetolactate synthase activity
CH61_2186	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_2187	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH61_2188	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH61_219	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH61_2191	COG0402	S-adenosylhomocysteine deaminase activity
CH61_2207	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH61_2208	COG3850	Histidine kinase
CH61_2209	COG0387	Pfam Sodium calcium exchanger
CH61_2210	COG1702	phosphate starvation-inducible protein PhoH
CH61_2213	COG3658	cytochrome
CH61_2214	COG1215	transferase activity, transferring glycosyl groups
CH61_2215	COG0726	polysaccharide deacetylase
CH61_2215	COG1649	PFAM Uncharacterised BCR, COG1649
CH61_2216	COG0457	Tetratricopeptide repeat
CH61_2217	COG0006	proline dipeptidase activity
CH61_2221	COG1136	(ABC) transporter
CH61_2221	COG0577	efflux transmembrane transporter activity
CH61_2223	COG1136	(ABC) transporter
CH61_2223	COG0577	efflux transmembrane transporter activity
CH61_2226	COG0672	)-iron permease
CH61_2228	COG2066	Belongs to the glutaminase family
CH61_2229	COG1349	DNA-binding transcription factor activity
CH61_2231	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH61_2232	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH61_2240	COG2030	dehydratase
CH61_2241	COG0427	acetyl-CoA hydrolase
CH61_2248	COG3188	usher protein
CH61_2250	COG3121	Chaperone
CH61_2252	COG0582	viral genome integration into host DNA
CH61_2253	COG1169	isochorismate synthase
CH61_2254	COG2814	Major facilitator Superfamily
CH61_2255	COG1132	(ABC) transporter
CH61_2258	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH61_2258	COG3433	isochorismatase activity
CH61_2258	COG2226	methyltransferase
CH61_2259	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH61_2259	COG2226	methyltransferase
CH61_2259	COG3433	isochorismatase activity
CH61_2263	COG1021	2,3-dihydroxybenzoate-AMP ligase
CH61_2264	COG4771	TonB-dependent receptor
CH61_2277	COG0395	ABC-type sugar transport system, permease component
CH61_2278	COG1175	transmembrane transport
CH61_228	COG0583	DNA-binding transcription factor activity
CH61_2280	COG0673	inositol 2-dehydrogenase activity
CH61_2287	COG3328	transposase activity
CH61_2288	COG3328	transposase activity
CH61_2311	COG2197	response regulator
CH61_2313	COG3136	membrane protein required for alginate biosynthesis
CH61_2317	COG1113	amino acid transport
CH61_2320	COG2837	iron assimilation
CH61_2325	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH61_2325	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH61_2325	COG0506	proline dehydrogenase activity
CH61_2331	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CH61_2333	COG1191	sigma factor activity
CH61_2339	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH61_234	COG3121	Chaperone
CH61_2340	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH61_2341	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH61_2344	COG1677	Flagellar hook-basal body complex protein FliE
CH61_2346	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH61_2348	COG1157	protein secretion by the type III secretion system
CH61_2349	COG2882	bacterial-type flagellum organization
CH61_2351	COG1580	Controls the rotational direction of flagella during chemotaxis
CH61_2356	COG1987	bacterial-type flagellum assembly
CH61_2360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_2361	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_2362	COG1129	ABC transporter
CH61_2364	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_2365	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_2365	COG3347	Dehydrogenase
CH61_2366	COG2390	Transcriptional regulator
CH61_2368	COG1256	bacterial-type flagellum assembly
CH61_237	COG3121	Chaperone
CH61_2372	COG4786	Flagellar basal body rod
CH61_2374	COG1749	Flagellar hook protein flgE
CH61_2375	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH61_2376	COG1558	bacterial-type flagellum-dependent cell motility
CH61_2377	COG1815	bacterial-type flagellum-dependent cell motility
CH61_2379	COG2747	anti-sigma28 factor FlgM
CH61_2380	COG3418	PFAM FlgN family protein
CH61_2382	COG1943	Transposase
CH61_2385	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH61_2386	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH61_239	COG3328	transposase activity
CH61_2391	COG2372	response to copper ion
CH61_2392	COG1528	Iron-storage protein
CH61_2395	COG1770	oligopeptidase
CH61_2398	COG3141	response to X-ray
CH61_2399	COG0513	Belongs to the DEAD box helicase family
CH61_24	COG3977	Valine--pyruvate aminotransferase
CH61_2404	COG1760	l-serine dehydratase
CH61_2405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH61_2406	COG2368	4-hydroxyphenylacetate
CH61_2409	COG3971	2-oxopent-4-enoate hydratase activity
CH61_241	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH61_2411	COG3384	dioxygenase
CH61_2412	COG1012	belongs to the aldehyde dehydrogenase family
CH61_2415	COG1846	Transcriptional regulator
CH61_2416	COG1253	flavin adenine dinucleotide binding
CH61_2417	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_2417	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_2418	COG3715	PTS system
CH61_2419	COG3716	PTS system mannose fructose sorbose family IID component
CH61_2423	COG5001	Diguanylate cyclase
CH61_2423	COG5002	protein histidine kinase activity
CH61_2423	COG3447	MASE1 domain protein
CH61_2425	COG2226	methyltransferase
CH61_2427	COG1278	Cold shock
CH61_2430	COG1113	amino acid transport
CH61_2437	COG2207	Transcriptional regulator
CH61_2439	COG1132	(ABC) transporter
CH61_2449	COG3328	transposase activity
CH61_2450	COG1917	Cupin 2, conserved barrel domain protein
CH61_2452	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_2454	COG1175	transmembrane transport
CH61_2455	COG0395	ABC-type sugar transport system, permease component
CH61_2456	COG3842	ATPase activity
CH61_2457	COG1653	transport
CH61_2458	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH61_2459	COG1988	membrane-bound metal-dependent
CH61_246	COG3118	belongs to the thioredoxin family
CH61_2461	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH61_2463	COG0823	Involved in the tonB-independent uptake of proteins
CH61_2464	COG2814	Major facilitator Superfamily
CH61_2465	COG3121	Chaperone
CH61_2468	COG3121	Chaperone
CH61_2469	COG3539	Fimbrial protein
CH61_247	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH61_2472	COG0793	Belongs to the peptidase S41A family
CH61_2474	COG1956	GAF domain-containing protein
CH61_2475	COG2995	paraquat-inducible protein a
CH61_2476	COG3008	intermembrane lipid transfer
CH61_248	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH61_2480	COG3121	Chaperone
CH61_249	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH61_2492	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH61_2495	COG5295	Hep Hag repeat protein
CH61_2497	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH61_2498	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH61_2499	COG0745	RESPONSE REGULATOR receiver
CH61_250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH61_2501	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH61_2504	COG0840	transmembrane signaling receptor activity
CH61_2508	COG2964	Protein conserved in bacteria
CH61_251	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH61_2510	COG0251	oxidation-reduction process
CH61_2511	COG2271	Major facilitator Superfamily
CH61_2512	COG0835	chemotaxis
CH61_2513	COG2198	Histidine kinase
CH61_2513	COG0643	Histidine kinase
CH61_2514	COG1360	Flagellar Motor Protein
CH61_2519	COG1285	pathogenesis
CH61_252	COG1088	dTDP-glucose 4,6-dehydratase activity
CH61_2520	COG0840	transmembrane signaling receptor activity
CH61_2521	COG0840	transmembrane signaling receptor activity
CH61_2523	COG1278	Cold shock
CH61_2525	COG0604	alcohol dehydrogenase
CH61_2525	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_2525	COG3321	synthase
CH61_2527	COG1522	sequence-specific DNA binding
CH61_253	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH61_2532	COG1733	regulation of RNA biosynthetic process
CH61_2533	COG0702	epimerase
CH61_2534	COG0840	transmembrane signaling receptor activity
CH61_2537	COG0538	isocitrate dehydrogenase activity
CH61_2538	COG1187	pseudouridine synthase activity
CH61_254	COG0456	acetyltransferase
CH61_2542	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH61_2544	COG0745	RESPONSE REGULATOR receiver
CH61_2546	COG2850	peptidyl-arginine hydroxylation
CH61_2548	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH61_255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH61_2550	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH61_2552	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH61_2553	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH61_2554	COG3134	Outer membrane lipoprotein
CH61_2557	COG3328	transposase activity
CH61_256	COG2244	polysaccharide biosynthetic process
CH61_2560	COG1252	NADH dehydrogenase
CH61_2562	COG1472	Belongs to the glycosyl hydrolase 3 family
CH61_2565	COG5633	Lipoprotein
CH61_2566	COG0537	adenosine 5'-monophosphoramidase activity
CH61_2567	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH61_2568	COG1943	Transposase
CH61_2569	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_2569	COG1263	PTS System
CH61_2570	COG0084	hydrolase, TatD family'
CH61_2571	COG0470	DNA polymerase III
CH61_2573	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH61_2574	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH61_2575	COG1943	Transposase
CH61_2577	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_2579	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_2583	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH61_2584	COG1399	metal-binding, possibly nucleic acid-binding protein
CH61_2586	COG1943	Transposase
CH61_2587	COG0564	pseudouridine synthase activity
CH61_2588	COG1530	ribonuclease E activity
CH61_2589	COG3328	transposase activity
CH61_2590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH61_2593	COG3328	transposase activity
CH61_2596	COG2223	nitrite transmembrane transporter activity
CH61_26	COG0366	Alpha amylase catalytic
CH61_260	COG1113	amino acid transport
CH61_2601	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH61_2606	COG3122	Protein conserved in bacteria
CH61_2610	COG0534	Mate efflux family protein
CH61_2614	COG4948	Mandelate Racemase Muconate Lactonizing
CH61_2616	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_2617	COG3011	Protein conserved in bacteria
CH61_2618	COG2271	Major facilitator Superfamily
CH61_2619	COG3328	transposase activity
CH61_2620	COG1388	LysM domain
CH61_2620	COG1470	cell adhesion involved in biofilm formation
CH61_2623	COG2925	Exonuclease
CH61_2624	COG0531	amino acid
CH61_2626	COG0371	Dehydrogenase
CH61_2627	COG1129	ABC transporter
CH61_2628	COG1129	ABC transporter
CH61_2629	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_2631	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_2633	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH61_2635	COG0131	Imidazoleglycerol-phosphate dehydratase
CH61_2635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH61_2636	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CH61_2639	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH61_2639	COG0140	phosphoribosyl-ATP diphosphatase activity
CH61_2641	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH61_2642	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH61_2645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH61_2646	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_2647	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_2648	COG1120	ATPase activity
CH61_2651	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH61_2652	COG0076	glutamate decarboxylase activity
CH61_2653	COG4114	ferric iron reductase
CH61_2654	COG1253	flavin adenine dinucleotide binding
CH61_2655	COG2982	Protein involved in outer membrane biogenesis
CH61_2658	COG0489	protein tyrosine kinase activity
CH61_2660	COG1943	Transposase
CH61_2667	COG2814	Major facilitator Superfamily
CH61_2669	COG1346	cytolysis
CH61_267	COG3071	HemY protein
CH61_2672	COG2949	membrane
CH61_2673	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH61_2676	COG2311	Membrane
CH61_2678	COG0477	Major facilitator Superfamily
CH61_2679	COG0583	DNA-binding transcription factor activity
CH61_268	COG2959	enzyme of heme biosynthesis
CH61_2685	COG1136	(ABC) transporter
CH61_2687	COG0303	'Molybdopterin
CH61_2689	COG3328	transposase activity
CH61_269	COG1587	Uroporphyrinogen-III synthase
CH61_2691	COG0488	(ABC) transporter
CH61_271	COG3072	Adenylate cyclase
CH61_2718	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH61_2719	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH61_2721	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_2722	COG1024	Enoyl-CoA hydratase
CH61_2724	COG3425	synthase
CH61_2725	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_2726	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_2727	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH61_2729	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_273	COG5567	small periplasmic lipoprotein
CH61_2736	COG2920	part of a sulfur-relay system
CH61_2740	COG1832	CoA-binding protein
CH61_2741	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CH61_2743	COG0210	DNA helicase
CH61_2744	COG3304	Inner membrane component domain
CH61_2745	COG1289	transmembrane transporter activity
CH61_2746	COG3070	regulator of competence-specific genes
CH61_2748	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH61_2748	COG2885	chlorophyll binding
CH61_2749	COG1943	Transposase
CH61_275	COG3159	Protein conserved in bacteria
CH61_2751	COG1067	ATP-dependent peptidase activity
CH61_2754	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_2759	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_276	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH61_2760	COG1943	Transposase
CH61_2761	COG3009	Protein conserved in bacteria
CH61_2762	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH61_2762	COG3008	intermembrane lipid transfer
CH61_2763	COG2995	paraquat-inducible protein a
CH61_2764	COG0488	(ABC) transporter
CH61_2766	COG3217	Mosc domain protein beta barrel domain protein
CH61_2766	COG0633	Ferredoxin
CH61_2769	COG0308	aminopeptidase N
CH61_277	COG1011	Hydrolase
CH61_2773	COG1943	Transposase
CH61_2774	COG1448	Aminotransferase
CH61_2775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH61_2776	COG3108	Peptidase M15
CH61_2777	COG2989	Protein conserved in bacteria
CH61_2778	COG1943	Transposase
CH61_278	COG0210	DNA helicase
CH61_2780	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CH61_2781	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH61_2782	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH61_2783	COG3173	Aminoglycoside phosphotransferase
CH61_2785	COG2835	tetraacyldisaccharide 4'-kinase activity
CH61_2786	COG1278	Cold shock
CH61_2787	COG5383	Protein conserved in bacteria
CH61_2790	COG2333	competence protein COMEC
CH61_2790	COG0658	competence protein
CH61_2793	COG0539	negative regulation of cytoplasmic translation
CH61_2798	COG5295	Hep Hag repeat protein
CH61_2798	COG5295	Hep Hag repeat protein
CH61_2799	COG0252	asparaginase activity
CH61_280	COG5441	Belongs to the UPF0261 family
CH61_2800	COG1944	ATP diphosphatase activity
CH61_2801	COG2116	formate transmembrane transporter activity
CH61_2802	COG1882	Formate acetyltransferase
CH61_2804	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH61_2805	COG2814	Major facilitator Superfamily
CH61_2807	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH61_281	COG5564	TIM-barrel signal transduction protein
CH61_2810	COG3107	peptidoglycan biosynthetic process
CH61_2810	COG1674	ftsk spoiiie
CH61_2812	COG0492	ferredoxin-NADP+ reductase activity
CH61_2814	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH61_2816	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH61_2817	COG1943	Transposase
CH61_2818	COG0542	response to heat
CH61_282	COG0598	Magnesium transport protein CorA
CH61_2820	COG1278	Cold shock
CH61_2822	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_2823	COG2990	Protein conserved in bacteria
CH61_2824	COG3593	DNA synthesis involved in DNA repair
CH61_2825	COG2431	L-lysine efflux transmembrane transporter activity
CH61_2827	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_2828	COG0028	Belongs to the TPP enzyme family
CH61_2829	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH61_2830	COG0702	epimerase
CH61_2831	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_2833	COG1605	Chorismate mutase
CH61_2834	COG1126	abc transporter atp-binding protein
CH61_2835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_2836	COG4215	(ABC) transporter
CH61_2837	COG4160	amino acid transport
CH61_284	COG2050	protein possibly involved in aromatic compounds catabolism
CH61_2841	COG1120	ATPase activity
CH61_2842	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_2847	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_285	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH61_2850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_2853	COG1177	transmembrane transport
CH61_2854	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH61_2855	COG3842	ATPase activity
CH61_2856	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH61_2859	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH61_286	COG0514	ATP-dependent DNA helicase (RecQ)
CH61_2860	COG0569	domain protein
CH61_2860	COG2985	domain, Protein
CH61_2862	COG0671	phosphoesterase, PA-phosphatase related
CH61_2863	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH61_2864	COG1349	DNA-binding transcription factor activity
CH61_2865	COG0814	amino acid
CH61_2866	COG1686	Belongs to the peptidase S11 family
CH61_2867	COG2011	ABC-type metal ion transport system permease component
CH61_287	COG1280	lysine exporter protein (LysE YggA)
CH61_2872	COG0625	glutathione transferase activity
CH61_2873	COG4771	TonB-dependent receptor
CH61_2875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_2877	COG0833	amino acid
CH61_2879	COG0583	DNA-binding transcription factor activity
CH61_288	COG1280	lysine exporter protein (LysE YggA)
CH61_2880	COG2855	membrane
CH61_2882	COG3188	usher protein
CH61_2883	COG3121	Chaperone
CH61_2886	COG3710	Transcriptional regulator
CH61_2887	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH61_2887	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_2887	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_2888	COG1105	Belongs to the carbohydrate kinase PfkB family
CH61_289	COG2267	carboxylic ester hydrolase activity
CH61_2890	COG0494	nUDIX hydrolase
CH61_2891	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_2892	COG1129	ABC transporter
CH61_2894	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH61_2899	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_29	COG2885	chlorophyll binding
CH61_290	COG0561	phosphatase activity
CH61_2903	COG1312	Catalyzes the dehydration of D-mannonate
CH61_2904	COG0246	Mannitol dehydrogenase
CH61_2905	COG2186	Transcriptional regulator
CH61_2907	COG0523	cobalamin synthesis protein
CH61_2908	COG0671	phosphoesterase, PA-phosphatase related
CH61_2909	COG0791	NLP P60 protein
CH61_2911	COG2200	EAL domain
CH61_2912	COG4166	transmembrane transport
CH61_2913	COG4174	ABC transporter (Permease)
CH61_2914	COG4239	(ABC) transporter, permease
CH61_2915	COG4172	Belongs to the ABC transporter superfamily
CH61_2917	COG2814	Major facilitator Superfamily
CH61_2918	COG1187	pseudouridine synthase activity
CH61_2919	COG1061	Type III restriction enzyme res subunit
CH61_292	COG0584	glycerophosphoryl diester phosphodiesterase
CH61_2921	COG1943	Transposase
CH61_2923	COG3082	Protein of unknown function (DUF1414)
CH61_2924	COG3083	sulfuric ester hydrolase activity
CH61_2927	COG3157	Type VI secretion system effector, Hcp
CH61_293	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH61_2931	COG2723	6-phospho-beta-galactosidase activity
CH61_2933	COG1737	Transcriptional regulator
CH61_2937	COG3299	homolog of phage Mu protein gp47
CH61_2945	COG4386	tail sheath protein
CH61_2949	COG3622	Belongs to the hyi family
CH61_295	COG0247	lactate metabolic process
CH61_2950	COG1349	DNA-binding transcription factor activity
CH61_2951	COG0235	Class ii aldolase
CH61_2952	COG3395	kinase activity
CH61_2961	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH61_2964	COG1943	Transposase
CH61_2965	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CH61_2967	COG2223	nitrite transmembrane transporter activity
CH61_2968	COG0642	Histidine kinase
CH61_2968	COG2198	Histidine kinase
CH61_2969	COG2198	Histidine kinase
CH61_2969	COG0642	Histidine kinase
CH61_297	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH61_2971	COG0784	Response regulator, receiver
CH61_2971	COG2205	protein histidine kinase activity
CH61_2976	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_2979	COG0814	amino acid
CH61_2984	COG0697	spore germination
CH61_2986	COG1982	Orn Lys Arg decarboxylase major
CH61_2987	COG0531	amino acid
CH61_2988	COG1174	glycine betaine transport
CH61_2989	COG1125	glycine betaine transport
CH61_2990	COG1174	glycine betaine transport
CH61_2993	COG2897	thiosulfate sulfurtransferase activity
CH61_2996	COG0410	ABC transporter
CH61_2997	COG1122	ATPase activity
CH61_3	COG0706	membrane insertase activity
CH61_300	COG3714	YhhN family
CH61_3001	COG4807	Protein conserved in bacteria
CH61_3004	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH61_3006	COG2261	transglycosylase associated protein
CH61_3008	COG1403	HNH endonuclease
CH61_3010	COG0277	FAD linked oxidase domain protein
CH61_3011	COG1686	Belongs to the peptidase S11 family
CH61_3013	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH61_3015	COG1943	Transposase
CH61_3016	COG2211	Major facilitator Superfamily
CH61_3017	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH61_3019	COG0583	DNA-binding transcription factor activity
CH61_3020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH61_3024	COG1943	Transposase
CH61_3025	COG0670	Belongs to the BI1 family
CH61_3026	COG0314	molybdopterin synthase activity
CH61_3027	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH61_3029	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH61_303	COG3776	membrane
CH61_3031	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH61_3032	COG4628	conserved protein (DUF2132)
CH61_3033	COG0556	nucleotide-excision repair
CH61_3035	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH61_3036	COG2226	methyltransferase
CH61_304	COG0742	ribosomal rna small subunit methyltransferase
CH61_3041	COG0561	phosphatase activity
CH61_3043	COG4149	molybdate abc transporter
CH61_3044	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH61_3046	COG3585	molybdate ion transport
CH61_3046	COG2005	Transcriptional regulator
CH61_3047	COG1119	ATPase activity
CH61_305	COG0552	protein localization to endoplasmic reticulum
CH61_305	COG0552	protein localization to endoplasmic reticulum
CH61_3050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH61_3051	COG1085	galactose-1-phosphate uridylyltransferase
CH61_3054	COG2017	converts alpha-aldose to the beta-anomer
CH61_3059	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH61_306	COG2884	Cell division ATP-binding protein ftsE
CH61_3061	COG1230	cation diffusion facilitator family transporter
CH61_3067	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH61_3068	COG2885	chlorophyll binding
CH61_307	COG2177	Part of the ABC transporter FtsEX involved in
CH61_3070	COG3064	Membrane
CH61_3070	COG3064	Membrane
CH61_3071	COG0848	biopolymer transport protein
CH61_3072	COG0811	peptide transport
CH61_3073	COG0824	Thioesterase
CH61_3074	COG3790	cyd operon protein YbgE
CH61_3075	COG4890	Cyd operon protein YbgT
CH61_3076	COG1294	oxidase, subunit
CH61_3077	COG1271	oxidase subunit
CH61_3078	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH61_3080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH61_3081	COG0567	Dehydrogenase, E1 component
CH61_3083	COG1053	succinate dehydrogenase
CH61_3084	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH61_3085	COG2009	succinate dehydrogenase
CH61_3088	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH61_3089	COG0497	DNA recombination
CH61_309	COG1943	Transposase
CH61_3090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH61_3092	COG2867	negative regulation of translational initiation
CH61_3094	COG1943	Transposase
CH61_3095	COG0582	viral genome integration into host DNA
CH61_31	COG2818	Glycosylase
CH61_3105	COG3657	addiction module killer protein
CH61_311	COG0683	leucine binding
CH61_3111	COG1953	Uracil, thiamine, allantoin
CH61_3113	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH61_3115	COG2226	methyltransferase
CH61_3117	COG1388	LysM domain
CH61_3117	COG0741	lytic transglycosylase activity
CH61_312	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH61_3120	COG0656	L-ascorbic acid biosynthetic process
CH61_3126	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH61_3128	COG2011	ABC-type metal ion transport system permease component
CH61_3129	COG1464	Belongs to the NlpA lipoprotein family
CH61_313	COG4177	L-phenylalanine transmembrane transporter activity
CH61_3131	COG1720	tRNA m6t6A37 methyltransferase activity
CH61_3133	COG3015	lipoprotein NlpE involved in copper resistance
CH61_3135	COG4681	YaeQ
CH61_3137	COG4568	rho-dependent transcription termination
CH61_3139	COG0037	tRNA processing
CH61_314	COG0411	ABC transporter
CH61_3140	COG0346	lactoylglutathione lyase activity
CH61_3142	COG0587	DNA-directed DNA polymerase activity
CH61_3144	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH61_3148	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH61_315	COG0410	ABC transporter
CH61_3150	COG0750	zinc metalloprotease
CH61_3151	COG0575	Belongs to the CDS family
CH61_3152	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH61_3158	COG0024	Methionine aminopeptidase
CH61_3163	COG0564	pseudouridine synthase activity
CH61_3164	COG3098	single-species biofilm formation
CH61_3165	COG1943	Transposase
CH61_3168	COG1611	Belongs to the LOG family
CH61_3169	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH61_3171	COG2363	Small membrane protein
CH61_3172	COG0583	DNA-binding transcription factor activity
CH61_3174	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH61_3175	COG2166	iron-sulfur cluster assembly
CH61_3176	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH61_3177	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH61_3180	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH61_3182	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH61_3183	COG1074	ATP-dependent DNA helicase activity
CH61_3185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH61_3193	COG4771	TonB-dependent receptor
CH61_3194	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH61_3195	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH61_3203	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_3205	COG5001	Diguanylate cyclase
CH61_3205	COG3300	MHYT domain
CH61_3206	COG2801	Transposase and inactivated derivatives
CH61_3208	COG2211	Major facilitator Superfamily
CH61_3218	COG3916	Acyl-homoserine-lactone synthase
CH61_3219	COG2771	luxR family
CH61_3240	COG1662	PFAM IS1 transposase
CH61_3244	COG1982	Orn Lys Arg decarboxylase major
CH61_3245	COG1879	ABC-type sugar transport system periplasmic component
CH61_3246	COG1129	ABC transporter
CH61_3247	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_3248	COG4774	siderophore transport
CH61_3252	COG1194	a g-specific adenine glycosylase
CH61_3254	COG3171	Protein conserved in bacteria
CH61_3255	COG2066	Belongs to the glutaminase family
CH61_3258	COG1073	alpha beta
CH61_3258	COG3064	Membrane
CH61_3258	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH61_3259	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH61_3260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH61_3262	COG0762	integral membrane protein
CH61_3263	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH61_3264	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH61_3265	COG2805	Type II/IV secretion system protein
CH61_3267	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH61_327	COG0584	glycerophosphoryl diester phosphodiesterase
CH61_3270	COG0189	ligase activity
CH61_3271	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH61_3272	COG2356	endonuclease I
CH61_3273	COG3091	SprT-like family
CH61_3276	COG1166	arginine decarboxylase activity
CH61_3278	COG0501	Belongs to the peptidase M48B family
CH61_3279	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH61_328	COG0679	Auxin Efflux Carrier
CH61_3280	COG1943	Transposase
CH61_3286	COG0191	fructose-bisphosphate aldolase activity
CH61_329	COG0583	DNA-binding transcription factor activity
CH61_3291	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH61_3292	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH61_3293	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH61_3296	COG0006	proline dipeptidase activity
CH61_3297	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH61_3298	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH61_3304	COG5295	Hep Hag repeat protein
CH61_3306	COG1272	protein, Hemolysin III
CH61_3309	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH61_3310	COG0745	RESPONSE REGULATOR receiver
CH61_3311	COG2205	protein histidine kinase activity
CH61_3312	COG4452	Inner membrane protein CreD
CH61_3313	COG0716	FMN binding
CH61_3314	COG4974	Belongs to the 'phage' integrase family
CH61_3315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH61_3316	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH61_332	COG0412	Dienelactone hydrolase
CH61_3320	COG0582	viral genome integration into host DNA
CH61_3325	COG2944	sequence-specific DNA binding
CH61_333	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CH61_3342	COG1695	Transcriptional regulator
CH61_3343	COG0791	NLP P60 protein
CH61_3345	COG1879	ABC-type sugar transport system periplasmic component
CH61_3346	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_3347	COG1129	ABC transporter
CH61_3349	COG2182	Extracellular solute-binding protein
CH61_335	COG1966	Carbon starvation protein
CH61_3350	COG1175	transmembrane transport
CH61_3351	COG3833	ABC-type maltose transport systems, permease component
CH61_3352	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH61_3353	COG1874	Beta-galactosidase
CH61_3354	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_3354	COG1263	PTS System
CH61_3358	COG2271	Major facilitator Superfamily
CH61_336	COG0586	Pfam SNARE associated Golgi protein
CH61_3362	COG0191	fructose-bisphosphate aldolase activity
CH61_3364	COG3119	arylsulfatase activity
CH61_3365	COG0641	radical SAM
CH61_3367	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_3369	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_337	COG1322	Protein conserved in bacteria
CH61_3370	COG3716	PTS system mannose fructose sorbose family IID component
CH61_3371	COG3715	PTS system
CH61_3372	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_3373	COG2222	sugar isomerase
CH61_3375	COG1349	DNA-binding transcription factor activity
CH61_3376	COG3119	arylsulfatase activity
CH61_3377	COG1943	Transposase
CH61_3385	COG0288	reversible hydration of carbon dioxide
CH61_3404	COG0840	transmembrane signaling receptor activity
CH61_3406	COG0583	DNA-binding transcription factor activity
CH61_3407	COG0583	DNA-binding transcription factor activity
CH61_3408	COG2814	Major facilitator Superfamily
CH61_3409	COG1609	Transcriptional regulator
CH61_341	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH61_3410	COG0019	diaminopimelate decarboxylase activity
CH61_3416	COG0667	Aldo Keto reductase
CH61_3426	COG3433	isochorismatase activity
CH61_3426	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH61_3426	COG2226	methyltransferase
CH61_3427	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH61_3428	COG3433	isochorismatase activity
CH61_3428	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH61_3428	COG2226	methyltransferase
CH61_343	COG0805	protein transport
CH61_3434	COG1132	(ABC) transporter
CH61_3438	COG2610	gluconate transmembrane transporter activity
CH61_3441	COG3501	Rhs element vgr protein
CH61_3443	COG3209	COG3209 Rhs family protein
CH61_3446	COG0471	metal ion transport
CH61_3448	COG2801	Transposase and inactivated derivatives
CH61_3451	COG3133	Outer membrane lipoprotein
CH61_3452	COG3133	Outer membrane lipoprotein
CH61_3457	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH61_3458	COG1191	sigma factor activity
CH61_3463	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH61_3467	COG3710	Transcriptional regulator
CH61_3471	COG1256	bacterial-type flagellum assembly
CH61_3473	COG1706	bacterial-type flagellum-dependent cell motility
CH61_3474	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH61_3475	COG4786	Flagellar basal body rod
CH61_3477	COG1943	Transposase
CH61_3479	COG1749	Flagellar hook protein flgE
CH61_3480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH61_3481	COG1558	bacterial-type flagellum-dependent cell motility
CH61_3482	COG1815	bacterial-type flagellum-dependent cell motility
CH61_3483	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH61_3492	COG2204	response regulator
CH61_3496	COG1987	bacterial-type flagellum assembly
CH61_3497	COG1684	flagellar biosynthetic protein fliR
CH61_3498	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH61_3503	COG4592	Periplasmic binding protein
CH61_3507	COG1943	Transposase
CH61_3508	COG1943	Transposase
CH61_3511	COG4964	Belongs to the GSP D family
CH61_3512	COG4964	Belongs to the GSP D family
CH61_3522	COG0848	biopolymer transport protein
CH61_3524	COG0811	peptide transport
CH61_3525	COG0626	cystathionine gamma-synthase activity
CH61_3526	COG0586	Pfam SNARE associated Golgi protein
CH61_3527	COG2207	Transcriptional regulator
CH61_3528	COG1979	alcohol dehydrogenase
CH61_3529	COG0656	L-ascorbic acid biosynthetic process
CH61_3532	COG2132	Multicopper oxidase
CH61_3533	COG0204	Acyl-transferase
CH61_3534	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH61_3535	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH61_3536	COG0583	DNA-binding transcription factor activity
CH61_3537	COG0187	DNA topoisomerase II activity
CH61_3538	COG3150	esterase
CH61_3539	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH61_3540	COG3151	Protein conserved in bacteria
CH61_3541	COG0494	nUDIX hydrolase
CH61_3542	COG1538	Outer membrane efflux protein
CH61_3545	COG0754	glutathionylspermidine amidase activity
CH61_3546	COG3384	dioxygenase
CH61_355	COG1739	Uncharacterized protein family UPF0029
CH61_3550	COG0531	amino acid
CH61_3553	COG3025	triphosphatase activity
CH61_3554	COG4991	sh3 domain protein
CH61_3557	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH61_356	COG1943	Transposase
CH61_3561	COG0358	DNA primase activity
CH61_3562	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH61_357	COG1739	Uncharacterized protein family UPF0029
CH61_3579	COG0251	oxidation-reduction process
CH61_358	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH61_3587	COG1289	transmembrane transporter activity
CH61_359	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH61_3591	COG0395	ABC-type sugar transport system, permease component
CH61_3593	COG1653	transport
CH61_3594	COG1609	Transcriptional regulator
CH61_3595	COG3459	Glycosyltransferase 36 associated
CH61_3596	COG3842	ATPase activity
CH61_36	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_36	COG2213	PTS system mannitol-specific
CH61_3600	COG3210	domain, Protein
CH61_3602	COG3210	domain, Protein
CH61_3604	COG3210	domain, Protein
CH61_3605	COG2831	hemolysin activation secretion protein
CH61_3606	COG4245	von Willebrand factor, type A
CH61_3609	COG4245	von Willebrand factor, type A
CH61_3612	COG3247	response to pH
CH61_3613	COG1902	pentaerythritol trinitrate reductase activity
CH61_3613	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH61_3616	COG1451	nucleotide metabolic process
CH61_3617	COG0673	inositol 2-dehydrogenase activity
CH61_3620	COG1943	Transposase
CH61_3622	COG2721	sulfolactate sulfo-lyase activity
CH61_3623	COG0246	Mannitol dehydrogenase
CH61_3625	COG2271	Major facilitator Superfamily
CH61_3628	COG0586	Pfam SNARE associated Golgi protein
CH61_3631	COG4575	ribosome binding
CH61_3632	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH61_3634	COG2259	Doxx family
CH61_3635	COG0435	Glutathione S-transferase
CH61_3638	COG0494	nUDIX hydrolase
CH61_3643	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH61_3644	COG0849	cell division
CH61_3645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH61_3649	COG0772	Belongs to the SEDS family
CH61_365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH61_3652	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH61_3653	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH61_3654	COG0768	penicillin binding
CH61_3655	COG3116	cell division
CH61_3659	COG1609	Transcriptional regulator
CH61_3660	COG1943	Transposase
CH61_3663	COG0028	Belongs to the TPP enzyme family
CH61_3664	COG1022	Amp-dependent synthetase and ligase
CH61_3667	COG1943	Transposase
CH61_3669	COG0473	3-isopropylmalate dehydrogenase activity
CH61_3672	COG2814	Major facilitator Superfamily
CH61_3676	COG2814	Major facilitator Superfamily
CH61_3679	COG4143	(ABC) transporter
CH61_3680	COG1178	ABC-type Fe3 transport system permease component
CH61_3682	COG0586	Pfam SNARE associated Golgi protein
CH61_3683	COG0417	DNA replication proofreading
CH61_3687	COG3047	cAMP biosynthetic process
CH61_3687	COG2885	chlorophyll binding
CH61_3695	COG3501	Rhs element vgr protein
CH61_3705	COG0564	pseudouridine synthase activity
CH61_3706	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH61_3708	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH61_3709	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH61_3714	COG1943	Transposase
CH61_3715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH61_3717	COG2966	Psort location CytoplasmicMembrane, score
CH61_3718	COG1280	lysine exporter protein (LysE YggA)
CH61_3719	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH61_3720	COG0505	Belongs to the CarA family
CH61_3722	COG1943	Transposase
CH61_3723	COG1943	Transposase
CH61_3725	COG1047	Peptidyl-prolyl cis-trans
CH61_3728	COG0196	riboflavin kinase activity
CH61_3730	COG0583	DNA-binding transcription factor activity
CH61_3734	COG1584	GPR1 FUN34 yaaH family protein
CH61_3737	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH61_3746	COG0745	RESPONSE REGULATOR receiver
CH61_3747	COG3045	CreA protein
CH61_3750	COG2207	Transcriptional regulator
CH61_3750	COG3708	Transcriptional regulator
CH61_3751	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH61_3753	COG0741	lytic transglycosylase activity
CH61_3756	COG2199	diguanylate cyclase activity
CH61_3757	COG2885	chlorophyll binding
CH61_3758	COG0488	(ABC) transporter
CH61_3759	COG0488	(ABC) transporter
CH61_3763	COG0560	Phosphoserine phosphatase
CH61_3764	COG3726	membrane protein affecting hemolysin expression
CH61_3769	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH61_377	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH61_3770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH61_3771	COG0084	hydrolase, TatD family'
CH61_3772	COG4667	esterase of the alpha-beta hydrolase superfamily
CH61_3774	COG2823	Periplasmic or secreted lipoprotein
CH61_3776	COG0456	acetyltransferase
CH61_3777	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH61_378	COG0250	Participates in transcription elongation, termination and antitermination
CH61_3781	COG3706	GGDEF domain
CH61_3784	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_3785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_3788	COG0859	PFAM glycosyl transferase family 9
CH61_3790	COG2390	Transcriptional regulator
CH61_3791	COG2390	Transcriptional regulator
CH61_3799	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_3799	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_3799	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH61_38	COG3722	fumarate hydratase activity
CH61_3800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_3801	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_3802	COG2207	Transcriptional regulator
CH61_3803	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_3805	COG4269	membrane
CH61_3815	COG2963	transposase activity
CH61_3817	COG1401	restriction endodeoxyribonuclease activity
CH61_3822	COG3650	response to hydrogen peroxide
CH61_3823	COG1960	acyl-CoA dehydrogenase activity
CH61_3824	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH61_3825	COG0557	exoribonuclease II activity
CH61_3828	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH61_3829	COG0330	HflC and HflK could
CH61_3830	COG0330	HflC and HflK could
CH61_3831	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH61_3835	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH61_3836	COG0802	atpase or kinase
CH61_3837	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH61_3837	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH61_3838	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH61_3841	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH61_3844	COG1511	domain protein
CH61_3844	COG3264	Mechanosensitive ion channel
CH61_3846	COG1053	succinate dehydrogenase
CH61_3847	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH61_3849	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH61_3850	COG1943	Transposase
CH61_3851	COG2076	Multidrug Resistance protein
CH61_3859	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_386	COG2022	thiamine diphosphate biosynthetic process
CH61_3862	COG3383	formate dehydrogenase (NAD+) activity
CH61_3863	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_3864	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_3864	COG0493	'glutamate synthase
CH61_3865	COG1309	transcriptional regulator
CH61_3879	COG1454	alcohol dehydrogenase
CH61_388	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH61_3881	COG0629	single-stranded DNA binding
CH61_3882	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH61_3883	COG2315	Protein conserved in bacteria
CH61_3884	COG1448	Aminotransferase
CH61_3885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH61_3886	COG0305	Participates in initiation and elongation during chromosome replication
CH61_3889	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH61_3890	COG0735	belongs to the Fur family
CH61_3892	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH61_390	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH61_3900	COG3121	Chaperone
CH61_3912	COG1358	cellular component organization or biogenesis
CH61_3917	COG3721	Heme iron utilization protein
CH61_3918	COG0702	epimerase
CH61_3919	COG4771	TonB-dependent receptor
CH61_3920	COG3720	iron ion transport
CH61_3921	COG4558	Periplasmic binding protein
CH61_3922	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_3924	COG0626	cystathionine gamma-synthase activity
CH61_3925	COG0814	amino acid
CH61_3926	COG0583	DNA-binding transcription factor activity
CH61_3927	COG0425	Belongs to the sulfur carrier protein TusA family
CH61_3928	COG2391	methyltransferase activity
CH61_395	COG1515	deoxyribonuclease V activity
CH61_3950	COG1301	dicarboxylic acid transport
CH61_3952	COG3162	membrane
CH61_3957	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH61_396	COG3068	Protein conserved in bacteria
CH61_3960	COG0551	DNA topoisomerase type I activity
CH61_3962	COG0758	DNA mediated transformation
CH61_3966	COG0569	domain protein
CH61_3968	COG3036	rescue of stalled ribosome
CH61_3969	COG0789	Transcriptional regulator
CH61_3972	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH61_3975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH61_3976	COG0201	protein transport
CH61_3978	COG1841	ribosomal large subunit assembly
CH61_3986	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH61_3987	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH61_3989	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH61_399	COG0151	Belongs to the GarS family
CH61_3990	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH61_3992	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH61_3997	COG0051	transcription antitermination factor activity, RNA binding
CH61_4000	COG1943	Transposase
CH61_4003	COG0049	tRNA binding
CH61_4004	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH61_4008	COG2964	Protein conserved in bacteria
CH61_4009	COG0545	Peptidyl-prolyl cis-trans isomerase
CH61_4011	COG1047	Peptidyl-prolyl cis-trans
CH61_4012	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH61_4015	COG0488	(ABC) transporter
CH61_4016	COG0488	(ABC) transporter
CH61_4017	COG1216	Glycosyl transferase, family 2
CH61_4019	COG2175	clavaminate synthase activity
CH61_4020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH61_4022	COG4521	taurine ABC transporter
CH61_4024	COG0429	hydrolase of the alpha beta-hydrolase fold
CH61_4026	COG3954	Phosphoribulokinase
CH61_4028	COG1765	OsmC-like protein
CH61_4030	COG1289	transmembrane transporter activity
CH61_4033	COG0433	COG0433 Predicted ATPase
CH61_4036	COG1486	melibiose metabolic process
CH61_4040	COG0402	S-adenosylhomocysteine deaminase activity
CH61_4041	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH61_4042	COG2146	nitrite reductase [NAD(P)H] activity
CH61_4045	COG0180	Tryptophanyl-tRNA synthetase
CH61_4046	COG0546	phosphoglycolate phosphatase activity
CH61_4047	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH61_4052	COG4796	Type ii and iii secretion system protein
CH61_4057	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH61_4058	COG0494	nUDIX hydrolase
CH61_4061	COG1011	Hydrolase
CH61_4062	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH61_4066	COG0745	RESPONSE REGULATOR receiver
CH61_4067	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH61_4068	COG2183	response to ionizing radiation
CH61_4069	COG1918	ferrous iron import across plasma membrane
CH61_4076	COG1640	4-alpha-glucanotransferase
CH61_4077	COG0058	SHG alpha-glucan phosphorylase activity
CH61_4078	COG0058	SHG alpha-glucan phosphorylase activity
CH61_4080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH61_4082	COG1349	DNA-binding transcription factor activity
CH61_4084	COG2801	Transposase and inactivated derivatives
CH61_4086	COG0460	homoserine dehydrogenase
CH61_4086	COG0527	aspartate kinase activity
CH61_4087	COG0626	cystathionine gamma-synthase activity
CH61_4088	COG0626	cystathionine gamma-synthase activity
CH61_4090	COG4682	membrane
CH61_4092	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH61_4094	COG1609	Transcriptional regulator
CH61_4095	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH61_4098	COG1575	Belongs to the MenA family. Type 1 subfamily
CH61_4107	COG1943	Transposase
CH61_4109	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH61_4110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH61_4111	COG1494	fructose-1,6-bisphosphatase
CH61_4113	COG3152	Membrane
CH61_4116	COG0583	DNA-binding transcription factor activity
CH61_4117	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH61_4118	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH61_4119	COG0471	metal ion transport
CH61_412	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH61_4121	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH61_4126	COG3678	ATP-independent chaperone mediated protein folding
CH61_4127	COG0745	RESPONSE REGULATOR receiver
CH61_4128	COG2205	protein histidine kinase activity
CH61_4129	COG2169	Transcriptional regulator
CH61_4129	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH61_413	COG2224	Isocitrate lyase
CH61_4130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH61_4131	COG1045	serine acetyltransferase
CH61_4134	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH61_4135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH61_4137	COG4942	peptidase
CH61_4138	COG2861	carbohydrate metabolic process
CH61_4139	COG2861	carbohydrate metabolic process
CH61_4141	COG0156	8-amino-7-oxononanoate synthase activity
CH61_4143	COG0859	PFAM glycosyl transferase family 9
CH61_4144	COG0859	PFAM glycosyl transferase family 9
CH61_4145	COG1519	Transferase
CH61_4149	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH61_415	COG1414	Transcriptional regulator
CH61_4152	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH61_4157	COG1561	YicC-like family, N-terminal region
CH61_4158	COG2860	membrane
CH61_4159	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH61_416	COG1414	Transcriptional regulator
CH61_4162	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH61_4163	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH61_4164	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH61_4165	COG0786	glutamate:sodium symporter activity
CH61_4166	COG2233	PERMEase
CH61_4167	COG2982	Protein involved in outer membrane biogenesis
CH61_4168	COG0456	acetyltransferase
CH61_4172	COG1295	ribonuclease BN
CH61_4173	COG1011	Hydrolase
CH61_4175	COG0174	glutamine synthetase
CH61_4176	COG3852	Histidine kinase
CH61_4178	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH61_4181	COG1943	Transposase
CH61_4183	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH61_4183	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH61_4184	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH61_4185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH61_4186	COG3084	Protein conserved in bacteria
CH61_4188	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH61_4189	COG3328	transposase activity
CH61_4190	COG3328	transposase activity
CH61_4195	COG2186	Transcriptional regulator
CH61_4197	COG0477	Major facilitator Superfamily
CH61_4198	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_420	COG0527	aspartate kinase activity
CH61_4204	COG1522	sequence-specific DNA binding
CH61_4205	COG0716	FMN binding
CH61_4208	COG3312	ion transport
CH61_4218	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH61_4219	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH61_4220	COG0573	inorganic phosphate transmembrane transporter activity
CH61_4221	COG0581	inorganic phosphate transmembrane transporter activity
CH61_4223	COG0704	Plays a role in the regulation of phosphate uptake
CH61_4225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_4226	COG0765	amino acid transport
CH61_4227	COG0765	amino acid transport
CH61_4228	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_4229	COG2252	PERMEase
CH61_423	COG3833	ABC-type maltose transport systems, permease component
CH61_4231	COG2963	transposase activity
CH61_4232	COG5599	Phosphatase
CH61_4233	COG1317	bacterial-type flagellum organization
CH61_4235	COG4669	(LipO)protein
CH61_424	COG1175	transmembrane transport
CH61_4244	COG2207	Transcriptional regulator
CH61_4246	COG4792	protein secretion
CH61_4247	COG4791	protein targeting
CH61_4248	COG4794	Type iii secretion
CH61_4249	COG4790	Type iii secretion
CH61_4250	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH61_4259	COG4789	Type iii secretion
CH61_4263	COG0457	Tetratricopeptide repeat
CH61_4267	COG4886	Leucine-rich repeat (LRR) protein
CH61_4271	COG3177	Filamentation induced by cAMP protein fic
CH61_4275	COG2801	Transposase and inactivated derivatives
CH61_4277	COG1192	Involved in chromosome partitioning
CH61_4278	COG1475	DNA binding
CH61_4280	COG3609	addiction module antidote protein, CC2985 family
CH61_4282	COG5599	Phosphatase
CH61_4284	COG2801	Transposase and inactivated derivatives
CH61_4292	COG2801	Transposase and inactivated derivatives
CH61_4297	COG2801	Transposase and inactivated derivatives
CH61_4316	COG0515	serine threonine protein kinase
CH61_4318	COG2801	Transposase and inactivated derivatives
CH61_4321	COG2801	Transposase and inactivated derivatives
CH61_4339	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH61_4341	COG3344	reverse transcriptase
CH61_4344	COG3328	transposase activity
CH61_435	COG2801	Transposase and inactivated derivatives
CH61_4365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH61_4367	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH61_4379	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH61_45	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH61_455	COG3501	Rhs element vgr protein
CH61_458	COG3209	COG3209 Rhs family protein
CH61_464	COG3501	Rhs element vgr protein
CH61_466	COG3209	COG3209 Rhs family protein
CH61_469	COG0673	inositol 2-dehydrogenase activity
CH61_47	COG3383	formate dehydrogenase (NAD+) activity
CH61_47	COG0243	molybdopterin cofactor binding
CH61_470	COG2207	Transcriptional regulator
CH61_470	COG1917	Cupin 2, conserved barrel domain protein
CH61_471	COG1869	D-ribose catabolic process
CH61_472	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_474	COG0431	NADPH-dependent FMN reductase
CH61_475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH61_477	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH61_479	COG3077	Addiction module antitoxin, RelB DinJ family
CH61_48	COG0243	molybdopterin cofactor binding
CH61_48	COG3383	formate dehydrogenase (NAD+) activity
CH61_480	COG2252	PERMEase
CH61_481	COG0025	NhaP-type Na H and K H
CH61_483	COG1560	Kdo2-lipid A biosynthetic process
CH61_485	COG1129	ABC transporter
CH61_486	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_488	COG1069	ribulokinase activity
CH61_49	COG0437	4 iron, 4 sulfur cluster binding
CH61_490	COG0625	glutathione transferase activity
CH61_493	COG1943	Transposase
CH61_494	COG1278	Cold shock
CH61_495	COG1278	Cold shock
CH61_496	COG3133	Outer membrane lipoprotein
CH61_497	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH61_499	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH61_50	COG2864	formate dehydrogenase
CH61_503	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH61_504	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH61_506	COG4145	pantothenate transmembrane transporter activity
CH61_507	COG3924	membrane
CH61_509	COG0439	Biotin carboxylase
CH61_510	COG0511	ligase activity, forming carbon-carbon bonds
CH61_513	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH61_514	COG0604	alcohol dehydrogenase
CH61_515	COG2200	EAL domain
CH61_515	COG2199	diguanylate cyclase activity
CH61_516	COG1077	Cell shape determining protein MreB Mrl
CH61_517	COG1792	Involved in formation and maintenance of cell shape
CH61_518	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH61_520	COG1530	ribonuclease E activity
CH61_521	COG3164	Protein of unknown function
CH61_522	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH61_523	COG0312	modulator of DNA gyrase
CH61_534	COG0583	DNA-binding transcription factor activity
CH61_538	COG1012	belongs to the aldehyde dehydrogenase family
CH61_541	COG2732	(Barnase) inhibitor
CH61_543	COG0312	modulator of DNA gyrase
CH61_545	COG3783	Cytochrome b(562)
CH61_546	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH61_547	COG0366	Alpha amylase catalytic
CH61_548	COG1263	PTS System
CH61_548	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_549	COG1609	Transcriptional regulator
CH61_559	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_561	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_563	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH61_564	COG1137	ATPase activity
CH61_565	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH61_566	COG3117	lipopolysaccharide transmembrane transporter activity
CH61_567	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH61_568	COG0517	IMP dehydrogenase activity
CH61_568	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH61_569	COG0530	calcium, potassium:sodium antiporter activity
CH61_570	COG1127	ABC transporter
CH61_571	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH61_572	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH61_573	COG2854	intermembrane phospholipid transfer
CH61_574	COG3113	response to antibiotic
CH61_575	COG5007	Belongs to the BolA IbaG family
CH61_577	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH61_578	COG1943	Transposase
CH61_579	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH61_580	COG3105	Protein conserved in bacteria
CH61_581	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH61_584	COG0625	glutathione transferase activity
CH61_585	COG2969	positive regulation of protein catabolic process
CH61_587	COG0493	'glutamate synthase
CH61_588	COG0069	glutamate synthase activity
CH61_588	COG0067	glutamate synthase
CH61_588	COG0070	glutamate synthase
CH61_589	COG1242	4 iron, 4 sulfur cluster binding
CH61_590	COG5002	protein histidine kinase activity
CH61_590	COG2198	Histidine kinase
CH61_590	COG0784	Response regulator, receiver
CH61_591	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH61_593	COG2823	Periplasmic or secreted lipoprotein
CH61_597	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH61_598	COG1741	Belongs to the pirin family
CH61_599	COG0583	DNA-binding transcription factor activity
CH61_6	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH61_600	COG0435	Glutathione S-transferase
CH61_605	COG1073	alpha beta
CH61_607	COG0360	Binds together with S18 to 16S ribosomal RNA
CH61_608	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH61_61	COG2801	Transposase and inactivated derivatives
CH61_610	COG1943	Transposase
CH61_612	COG3061	Opacity-associated protein A
CH61_613	COG0545	Peptidyl-prolyl cis-trans isomerase
CH61_615	COG0737	Belongs to the 5'-nucleotidase family
CH61_617	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH61_619	COG1253	flavin adenine dinucleotide binding
CH61_621	COG0729	surface antigen
CH61_622	COG2911	Protein conserved in bacteria
CH61_623	COG2105	PFAM AIG2 family protein
CH61_624	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH61_626	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH61_63	COG3274	enterobacterial common antigen metabolic process
CH61_630	COG3423	Transcriptional regulator
CH61_632	COG0142	geranyltranstransferase activity
CH61_635	COG0697	spore germination
CH61_637	COG0642	Histidine kinase
CH61_638	COG0745	RESPONSE REGULATOR receiver
CH61_639	COG2027	D-alanyl-D-alanine carboxypeptidase
CH61_640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH61_641	COG1534	Rna-binding protein
CH61_643	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH61_644	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH61_646	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH61_65	COG3188	usher protein
CH61_650	COG0195	Participates in both transcription termination and antitermination
CH61_656	COG2801	Transposase and inactivated derivatives
CH61_659	COG0513	Belongs to the DEAD box helicase family
CH61_66	COG3188	usher protein
CH61_662	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH61_665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_67	COG3121	Chaperone
CH61_670	COG3153	acetyltransferase
CH61_674	COG1653	transport
CH61_676	COG0395	ABC-type sugar transport system, permease component
CH61_677	COG3842	ATPase activity
CH61_680	COG0702	epimerase
CH61_681	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH61_682	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH61_683	COG3454	Phosphonate metabolism
CH61_684	COG4778	phosphonate C-P lyase system protein PhnL
CH61_685	COG4107	phosphonate C-P lyase system protein PhnK
CH61_686	COG3627	carbon phosphorus lyase activity
CH61_687	COG3626	phosphonate metabolism
CH61_688	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH61_689	COG3624	Phosphonate C-P lyase system protein PhnG
CH61_69	COG1070	Carbohydrate kinase
CH61_690	COG2188	Transcriptional regulator
CH61_694	COG4608	Belongs to the ABC transporter superfamily
CH61_695	COG0444	Belongs to the ABC transporter superfamily
CH61_696	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_697	COG0601	transmembrane transport
CH61_700	COG2731	YhcH YjgK YiaL family protein
CH61_701	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CH61_702	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH61_704	COG0525	valine-tRNA ligase activity
CH61_705	COG2927	DNA polymerase III (CHI subunit)
CH61_707	COG0795	lipopolysaccharide-transporting ATPase activity
CH61_708	COG0795	lipopolysaccharide-transporting ATPase activity
CH61_71	COG4213	ABC transporter substrate-binding protein
CH61_710	COG0582	viral genome integration into host DNA
CH61_716	COG1943	Transposase
CH61_719	COG0237	dephospho-CoA kinase activity
CH61_721	COG1459	type II secretion system
CH61_722	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH61_723	COG4969	Belongs to the N-Me-Phe pilin family
CH61_725	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH61_726	COG3725	Membrane protein required for beta-lactamase induction
CH61_727	COG1113	amino acid transport
CH61_728	COG2186	Transcriptional regulator
CH61_729	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH61_73	COG4214	carbohydrate transport
CH61_730	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH61_731	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH61_732	COG1943	Transposase
CH61_733	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH61_735	COG0697	spore germination
CH61_739	COG2132	Multicopper oxidase
CH61_74	COG1609	Transcriptional regulator
CH61_74	COG2207	Transcriptional regulator
CH61_740	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH61_741	COG0288	reversible hydration of carbon dioxide
CH61_742	COG1131	(ABC) transporter
CH61_743	COG0842	Transport permease protein
CH61_744	COG0726	polysaccharide deacetylase
CH61_748	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH61_749	COG0617	tRNA 3'-terminal CCA addition
CH61_750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH61_751	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH61_753	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH61_754	COG1643	Atp-dependent helicase
CH61_755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH61_756	COG1120	ATPase activity
CH61_757	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH61_758	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_76	COG0582	viral genome integration into host DNA
CH61_762	COG2860	membrane
CH61_764	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH61_766	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH61_767	COG3437	response regulator, receiver
CH61_767	COG2205	protein histidine kinase activity
CH61_767	COG4999	Histidine kinase
CH61_767	COG3850	Histidine kinase
CH61_768	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH61_769	COG3956	TIGRFAM MazG family protein
CH61_773	COG0602	queuosine metabolic process
CH61_774	COG0720	synthase
CH61_785	COG0529	Catalyzes the synthesis of activated sulfate
CH61_788	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CH61_793	COG4942	peptidase
CH61_793	COG1388	LysM domain
CH61_794	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH61_795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH61_796	COG0698	ribose 5-phosphate isomerase
CH61_797	COG1063	alcohol dehydrogenase
CH61_798	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_799	COG2376	Dihydroxyacetone kinase
CH61_802	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH61_806	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_807	COG1858	cytochrome C peroxidase
CH61_809	COG4771	TonB-dependent receptor
CH61_812	COG0024	Methionine aminopeptidase
CH61_814	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH61_814	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH61_815	COG1070	Carbohydrate kinase
CH61_816	COG3623	hexulose-6-phosphate isomerase
CH61_817	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_818	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_819	COG1129	ABC transporter
CH61_820	COG1943	Transposase
CH61_823	COG1349	DNA-binding transcription factor activity
CH61_824	COG0235	Class ii aldolase
CH61_825	COG0243	molybdopterin cofactor binding
CH61_826	COG0437	4 iron, 4 sulfur cluster binding
CH61_827	COG3302	dmso reductase anchor subunit
CH61_828	COG3381	protein complex oligomerization
CH61_829	COG3038	cytochrome b561
CH61_83	COG4604	ABC transporter, ATP-binding protein
CH61_830	COG3783	Cytochrome b(562)
CH61_834	COG1129	ABC transporter
CH61_835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_836	COG3959	Transketolase, thiamine diphosphate binding domain
CH61_837	COG3958	Transketolase
CH61_838	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH61_845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH61_846	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH61_85	COG4605	iron ion homeostasis
CH61_851	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_852	COG1238	metal cluster binding
CH61_853	COG2918	glutathione biosynthetic process
CH61_855	COG1943	Transposase
CH61_856	COG1943	Transposase
CH61_857	COG4536	flavin adenine dinucleotide binding
CH61_858	COG4137	Cytochrome C assembly protein
CH61_859	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH61_864	COG1943	Transposase
CH61_865	COG3137	Salt-induced outer membrane protein
CH61_866	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_867	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_868	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_869	COG3279	Response regulator of the LytR AlgR family
CH61_87	COG4607	ABC-type enterochelin transport system periplasmic component
CH61_870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH61_871	COG1605	Chorismate mutase
CH61_871	COG0287	Prephenate dehydrogenase
CH61_872	COG0077	Prephenate dehydratase
CH61_872	COG1605	Chorismate mutase
CH61_876	COG0077	Prephenate dehydratase
CH61_876	COG1605	Chorismate mutase
CH61_877	COG1943	Transposase
CH61_878	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH61_879	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH61_880	COG0564	pseudouridine synthase activity
CH61_882	COG0542	response to heat
CH61_889	COG5544	Lipoprotein
CH61_890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH61_891	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH61_891	COG1042	CoA-binding domain protein
CH61_891	COG0045	succinate-CoA ligase (ADP-forming) activity
CH61_893	COG3118	belongs to the thioredoxin family
CH61_894	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH61_895	COG2814	Major facilitator Superfamily
CH61_896	COG1566	PFAM secretion protein HlyD family protein
CH61_897	COG1846	Transcriptional regulator
CH61_899	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH61_9	COG0592	DNA-directed DNA polymerase activity
CH61_90	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH61_900	COG2814	Major facilitator Superfamily
CH61_909	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH61_913	COG2113	Glycine betaine
CH61_914	COG4176	ABC-type proline glycine betaine transport system permease component
CH61_915	COG4175	Glycine betaine
CH61_916	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH61_924	COG3328	transposase activity
CH61_926	COG1278	Cold shock
CH61_927	COG0747	negative chemotaxis
CH61_929	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_93	COG2986	histidine ammonia-lyase
CH61_930	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH61_931	COG1124	(ABC) transporter
CH61_938	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH61_940	COG4413	Urea transporter
CH61_941	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH61_943	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH61_944	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH61_945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH61_946	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH61_947	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH61_948	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH61_949	COG1917	Cupin 2, conserved barrel domain protein
CH61_949	COG2169	Transcriptional regulator
CH61_953	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH61_954	COG0033	Phosphoglucomutase
CH61_958	COG0745	RESPONSE REGULATOR receiver
CH61_959	COG2205	protein histidine kinase activity
CH61_96	COG2194	sulfuric ester hydrolase activity
CH61_964	COG3272	Protein of unknown function (DUF1722)
CH61_966	COG5212	phosphodiesterase
CH61_967	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH61_969	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH61_97	COG2197	response regulator
CH61_970	COG1984	allophanate hydrolase subunit 2
CH61_98	COG3851	Histidine kinase
CH61_981	COG0513	Belongs to the DEAD box helicase family
CH61_983	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH61_985	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH61_986	COG3026	antisigma factor binding
CH61_987	COG3086	response to oxidative stress
CH61_990	COG0681	Belongs to the peptidase S26 family
CH61_999	COG3501	Rhs element vgr protein