locus-tag	class	description
AH66_000010	COG0592	DNA-directed DNA polymerase activity
AH66_000020	COG0187	DNA topoisomerase II activity
AH66_000025	COG0561	phosphatase activity
AH66_000035	COG2423	ornithine cyclodeaminase activity
AH66_000040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AH66_000050	COG5645	(Lipo)protein
AH66_000070	COG3977	Valine--pyruvate aminotransferase
AH66_000080	COG0366	Alpha amylase catalytic
AH66_000095	COG2885	chlorophyll binding
AH66_000105	COG2818	Glycosylase
AH66_000130	COG2213	PTS system mannitol-specific
AH66_000130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_000140	COG3722	fumarate hydratase activity
AH66_000165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AH66_000180	COG0437	4 iron, 4 sulfur cluster binding
AH66_000185	COG2864	formate dehydrogenase
AH66_000245	COG3274	enterobacterial common antigen metabolic process
AH66_000260	COG3121	Chaperone
AH66_000270	COG1070	Carbohydrate kinase
AH66_000280	COG4213	ABC transporter substrate-binding protein
AH66_000290	COG4214	carbohydrate transport
AH66_000295	COG1609	Transcriptional regulator
AH66_000295	COG2207	Transcriptional regulator
AH66_000305	COG0582	viral genome integration into host DNA
AH66_000350	COG4604	ABC transporter, ATP-binding protein
AH66_000355	COG4605	iron ion homeostasis
AH66_000365	COG4607	ABC-type enterochelin transport system periplasmic component
AH66_000395	COG2986	histidine ammonia-lyase
AH66_000410	COG2194	sulfuric ester hydrolase activity
AH66_000415	COG2197	response regulator
AH66_000420	COG3851	Histidine kinase
AH66_000425	COG2271	Major facilitator Superfamily
AH66_000440	COG2831	hemolysin activation secretion protein
AH66_000445	COG0747	negative chemotaxis
AH66_000455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_000460	COG0444	Belongs to the ABC transporter superfamily
AH66_000465	COG4608	Belongs to the ABC transporter superfamily
AH66_000470	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AH66_000475	COG2200	EAL domain
AH66_000475	COG2199	diguanylate cyclase activity
AH66_000480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AH66_000500	COG0612	Peptidase, M16
AH66_000505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_000510	COG1942	4-Oxalocrotonate Tautomerase
AH66_000515	COG2200	EAL domain
AH66_000520	COG2982	Protein involved in outer membrane biogenesis
AH66_000525	COG2134	cdp-diacylglycerol pyrophosphatase
AH66_000530	COG1295	ribonuclease BN
AH66_000555	COG1929	Belongs to the glycerate kinase type-1 family
AH66_000560	COG2610	gluconate transmembrane transporter activity
AH66_000570	COG3835	regulator
AH66_000575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AH66_000580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AH66_000585	COG0339	signal peptide processing
AH66_000605	COG0589	response to stress
AH66_000620	COG0306	phosphate transporter
AH66_000625	COG2081	HI0933 family
AH66_000640	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_000655	COG0191	fructose-bisphosphate aldolase activity
AH66_000675	COG1741	Belongs to the pirin family
AH66_000680	COG1609	Transcriptional regulator
AH66_000685	COG2610	gluconate transmembrane transporter activity
AH66_000690	COG3265	gluconokinase activity
AH66_000705	COG2095	MarC family integral membrane protein
AH66_000710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AH66_000745	COG3275	phosphorelay sensor kinase activity
AH66_000770	COG0058	SHG alpha-glucan phosphorylase activity
AH66_000775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AH66_000825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AH66_000840	COG1629	transport
AH66_000865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AH66_000870	COG0678	peroxiredoxin activity
AH66_000870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AH66_000940	COG1879	ABC-type sugar transport system periplasmic component
AH66_000945	COG1129	ABC transporter
AH66_000950	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_000955	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_000965	COG3085	chromosome segregation
AH66_000985	COG3978	acetolactate synthase activity
AH66_000990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AH66_001035	COG0583	DNA-binding transcription factor activity
AH66_001070	COG3121	Chaperone
AH66_001085	COG3121	Chaperone
AH66_001095	COG3328	transposase activity
AH66_001105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AH66_001130	COG3118	belongs to the thioredoxin family
AH66_001135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AH66_001140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AH66_001145	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AH66_001150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AH66_001155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AH66_001160	COG1088	dTDP-glucose 4,6-dehydratase activity
AH66_001165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AH66_001170	COG0456	acetyltransferase
AH66_001175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AH66_001180	COG2244	polysaccharide biosynthetic process
AH66_001200	COG1113	amino acid transport
AH66_001230	COG3071	HemY protein
AH66_001235	COG2959	enzyme of heme biosynthesis
AH66_001240	COG1587	Uroporphyrinogen-III synthase
AH66_001255	COG3072	Adenylate cyclase
AH66_001275	COG3159	Protein conserved in bacteria
AH66_001280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AH66_001285	COG1011	Hydrolase
AH66_001290	COG0210	DNA helicase
AH66_001300	COG5441	Belongs to the UPF0261 family
AH66_001305	COG5564	TIM-barrel signal transduction protein
AH66_001320	COG2050	protein possibly involved in aromatic compounds catabolism
AH66_001325	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AH66_001330	COG0514	ATP-dependent DNA helicase (RecQ)
AH66_001335	COG1280	lysine exporter protein (LysE YggA)
AH66_001340	COG1280	lysine exporter protein (LysE YggA)
AH66_001345	COG2267	carboxylic ester hydrolase activity
AH66_001350	COG0561	phosphatase activity
AH66_001360	COG0584	glycerophosphoryl diester phosphodiesterase
AH66_001365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AH66_001375	COG0247	lactate metabolic process
AH66_001385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AH66_001400	COG3714	YhhN family
AH66_001415	COG3776	membrane
AH66_001420	COG0742	ribosomal rna small subunit methyltransferase
AH66_001425	COG0552	protein localization to endoplasmic reticulum
AH66_001425	COG0552	protein localization to endoplasmic reticulum
AH66_001430	COG2884	Cell division ATP-binding protein ftsE
AH66_001435	COG2177	Part of the ABC transporter FtsEX involved in
AH66_001455	COG0683	leucine binding
AH66_001465	COG4177	L-phenylalanine transmembrane transporter activity
AH66_001475	COG0410	ABC transporter
AH66_001535	COG0584	glycerophosphoryl diester phosphodiesterase
AH66_001540	COG0679	Auxin Efflux Carrier
AH66_001545	COG0697	spore germination
AH66_001550	COG0583	DNA-binding transcription factor activity
AH66_001560	COG0412	Dienelactone hydrolase
AH66_001575	COG1966	Carbon starvation protein
AH66_001580	COG0586	Pfam SNARE associated Golgi protein
AH66_001585	COG1322	Protein conserved in bacteria
AH66_001605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AH66_001615	COG0805	protein transport
AH66_001650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AH66_001675	COG1739	Uncharacterized protein family UPF0029
AH66_001690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AH66_001695	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AH66_001725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AH66_001785	COG0250	Participates in transcription elongation, termination and antitermination
AH66_001830	COG2022	thiamine diphosphate biosynthetic process
AH66_001840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AH66_001875	COG1515	deoxyribonuclease V activity
AH66_001895	COG0151	Belongs to the GarS family
AH66_001945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AH66_001950	COG2224	Isocitrate lyase
AH66_001980	COG0527	aspartate kinase activity
AH66_001995	COG3833	ABC-type maltose transport systems, permease component
AH66_002000	COG1175	transmembrane transport
AH66_002130	COG3501	Rhs element vgr protein
AH66_002175	COG3501	Rhs element vgr protein
AH66_002185	COG3209	COG3209 Rhs family protein
AH66_002205	COG0673	inositol 2-dehydrogenase activity
AH66_002210	COG2207	Transcriptional regulator
AH66_002210	COG1917	Cupin 2, conserved barrel domain protein
AH66_002215	COG1869	D-ribose catabolic process
AH66_002220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_002225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AH66_002230	COG0431	NADPH-dependent FMN reductase
AH66_002235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AH66_002245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AH66_002260	COG3077	Addiction module antitoxin, RelB DinJ family
AH66_002265	COG2252	PERMEase
AH66_002270	COG0025	NhaP-type Na H and K H
AH66_002280	COG1560	Kdo2-lipid A biosynthetic process
AH66_002290	COG1129	ABC transporter
AH66_002295	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_002305	COG1069	ribulokinase activity
AH66_002315	COG0625	glutathione transferase activity
AH66_002335	COG1278	Cold shock
AH66_002340	COG1278	Cold shock
AH66_002345	COG3133	Outer membrane lipoprotein
AH66_002350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AH66_002360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AH66_002390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AH66_002395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AH66_002405	COG4145	pantothenate transmembrane transporter activity
AH66_002410	COG3924	membrane
AH66_002420	COG0439	Biotin carboxylase
AH66_002425	COG0511	ligase activity, forming carbon-carbon bonds
AH66_002440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AH66_002445	COG0604	alcohol dehydrogenase
AH66_002450	COG2200	EAL domain
AH66_002450	COG2199	diguanylate cyclase activity
AH66_002455	COG1077	Cell shape determining protein MreB Mrl
AH66_002460	COG1792	Involved in formation and maintenance of cell shape
AH66_002465	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AH66_002470	COG0424	maF-like protein
AH66_002475	COG1530	ribonuclease E activity
AH66_002480	COG3164	Protein of unknown function
AH66_002485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AH66_002490	COG0312	modulator of DNA gyrase
AH66_002545	COG0583	DNA-binding transcription factor activity
AH66_002575	COG2732	(Barnase) inhibitor
AH66_002585	COG0312	modulator of DNA gyrase
AH66_002595	COG3783	Cytochrome b(562)
AH66_002600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AH66_002605	COG0366	Alpha amylase catalytic
AH66_002610	COG1263	PTS System
AH66_002610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_002615	COG1609	Transcriptional regulator
AH66_002650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_002670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AH66_002675	COG1137	ATPase activity
AH66_002680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AH66_002685	COG3117	lipopolysaccharide transmembrane transporter activity
AH66_002690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AH66_002695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AH66_002695	COG0517	IMP dehydrogenase activity
AH66_002700	COG0530	calcium, potassium:sodium antiporter activity
AH66_002705	COG1127	ABC transporter
AH66_002710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AH66_002715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AH66_002720	COG2854	intermembrane phospholipid transfer
AH66_002725	COG3113	response to antibiotic
AH66_002730	COG5007	Belongs to the BolA IbaG family
AH66_002740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AH66_002750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AH66_002755	COG3105	Protein conserved in bacteria
AH66_002760	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AH66_002780	COG0625	glutathione transferase activity
AH66_002785	COG2969	positive regulation of protein catabolic process
AH66_002795	COG0493	'glutamate synthase
AH66_002800	COG0067	glutamate synthase
AH66_002800	COG0069	glutamate synthase activity
AH66_002800	COG0070	glutamate synthase
AH66_002805	COG1242	4 iron, 4 sulfur cluster binding
AH66_002810	COG0784	Response regulator, receiver
AH66_002810	COG2198	Histidine kinase
AH66_002810	COG5002	protein histidine kinase activity
AH66_002815	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AH66_002825	COG2823	Periplasmic or secreted lipoprotein
AH66_002845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AH66_002855	COG1741	Belongs to the pirin family
AH66_002860	COG0583	DNA-binding transcription factor activity
AH66_002905	COG1459	type II secretion system
AH66_002910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AH66_002915	COG4969	Belongs to the N-Me-Phe pilin family
AH66_002925	COG3023	N-Acetylmuramoyl-L-alanine amidase
AH66_002930	COG3725	Membrane protein required for beta-lactamase induction
AH66_002935	COG1113	amino acid transport
AH66_002940	COG2186	Transcriptional regulator
AH66_002945	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AH66_002950	COG0508	dehydrogenase complex catalyzes the overall conversion of
AH66_002955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AH66_002965	COG1049	propionate catabolic process, 2-methylcitrate cycle
AH66_002975	COG0697	spore germination
AH66_002995	COG2132	Multicopper oxidase
AH66_003000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AH66_003005	COG0288	reversible hydration of carbon dioxide
AH66_003010	COG1131	(ABC) transporter
AH66_003015	COG0842	Transport permease protein
AH66_003020	COG0726	polysaccharide deacetylase
AH66_003040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AH66_003045	COG0617	tRNA 3'-terminal CCA addition
AH66_003050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AH66_003065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AH66_003070	COG1643	Atp-dependent helicase
AH66_003075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AH66_003080	COG1120	ATPase activity
AH66_003085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AH66_003090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_003110	COG2860	membrane
AH66_003130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AH66_003135	COG2205	protein histidine kinase activity
AH66_003135	COG3437	response regulator, receiver
AH66_003135	COG3850	Histidine kinase
AH66_003135	COG4999	Histidine kinase
AH66_003145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AH66_003150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AH66_003155	COG3956	TIGRFAM MazG family protein
AH66_003175	COG0602	queuosine metabolic process
AH66_003180	COG0720	synthase
AH66_003235	COG0529	Catalyzes the synthesis of activated sulfate
AH66_003275	COG1388	LysM domain
AH66_003275	COG4942	peptidase
AH66_003280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AH66_003290	COG0698	ribose 5-phosphate isomerase
AH66_003295	COG1063	alcohol dehydrogenase
AH66_003300	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_003305	COG2376	Dihydroxyacetone kinase
AH66_003320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AH66_003340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_003345	COG1858	cytochrome C peroxidase
AH66_003355	COG4771	TonB-dependent receptor
AH66_003370	COG0024	Methionine aminopeptidase
AH66_003380	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AH66_003380	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AH66_003385	COG1070	Carbohydrate kinase
AH66_003390	COG3623	hexulose-6-phosphate isomerase
AH66_003395	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_003400	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_003405	COG1129	ABC transporter
AH66_003420	COG1349	DNA-binding transcription factor activity
AH66_003425	COG0235	Class ii aldolase
AH66_003430	COG0243	molybdopterin cofactor binding
AH66_003435	COG0437	4 iron, 4 sulfur cluster binding
AH66_003440	COG3302	dmso reductase anchor subunit
AH66_003445	COG3381	protein complex oligomerization
AH66_003450	COG3038	cytochrome b561
AH66_003455	COG3783	Cytochrome b(562)
AH66_003465	COG1879	ABC-type sugar transport system periplasmic component
AH66_003475	COG1129	ABC transporter
AH66_003480	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_003485	COG3959	Transketolase, thiamine diphosphate binding domain
AH66_003490	COG3958	Transketolase
AH66_003495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AH66_003535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AH66_003540	COG3328	transposase activity
AH66_003575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_003580	COG1238	metal cluster binding
AH66_003585	COG2918	glutathione biosynthetic process
AH66_003605	COG4536	flavin adenine dinucleotide binding
AH66_003610	COG4137	Cytochrome C assembly protein
AH66_003615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AH66_003645	COG3137	Salt-induced outer membrane protein
AH66_003655	COG3279	Response regulator of the LytR AlgR family
AH66_003660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AH66_003665	COG0287	Prephenate dehydrogenase
AH66_003665	COG1605	Chorismate mutase
AH66_003670	COG1605	Chorismate mutase
AH66_003670	COG0077	Prephenate dehydratase
AH66_003685	COG1073	alpha beta
AH66_003690	COG0360	Binds together with S18 to 16S ribosomal RNA
AH66_003700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AH66_003720	COG3061	Opacity-associated protein A
AH66_003725	COG0545	Peptidyl-prolyl cis-trans isomerase
AH66_003735	COG0737	Belongs to the 5'-nucleotidase family
AH66_003745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AH66_003755	COG1253	flavin adenine dinucleotide binding
AH66_003765	COG0729	surface antigen
AH66_003770	COG2911	Protein conserved in bacteria
AH66_003775	COG2105	PFAM AIG2 family protein
AH66_003780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AH66_003785	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AH66_003790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AH66_003810	COG3423	Transcriptional regulator
AH66_003820	COG0142	geranyltranstransferase activity
AH66_003835	COG0697	spore germination
AH66_003845	COG0642	Histidine kinase
AH66_003850	COG0745	RESPONSE REGULATOR receiver
AH66_003855	COG2027	D-alanyl-D-alanine carboxypeptidase
AH66_003865	COG1534	Rna-binding protein
AH66_003880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AH66_003890	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AH66_003910	COG0195	Participates in both transcription termination and antitermination
AH66_003955	COG0513	Belongs to the DEAD box helicase family
AH66_003975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AH66_003985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_003995	COG0826	peptidase U32
AH66_004000	COG0826	peptidase U32
AH66_004005	COG3154	lipid carrier protein
AH66_004010	COG3153	acetyltransferase
AH66_004030	COG1653	transport
AH66_004035	COG1175	transmembrane transport
AH66_004040	COG0395	ABC-type sugar transport system, permease component
AH66_004045	COG3842	ATPase activity
AH66_004060	COG0702	epimerase
AH66_004065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AH66_004070	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AH66_004075	COG3454	Phosphonate metabolism
AH66_004080	COG4778	phosphonate C-P lyase system protein PhnL
AH66_004085	COG4107	phosphonate C-P lyase system protein PhnK
AH66_004090	COG3627	carbon phosphorus lyase activity
AH66_004095	COG3626	phosphonate metabolism
AH66_004100	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AH66_004105	COG3624	Phosphonate C-P lyase system protein PhnG
AH66_004110	COG2188	Transcriptional regulator
AH66_004125	COG4608	Belongs to the ABC transporter superfamily
AH66_004130	COG0444	Belongs to the ABC transporter superfamily
AH66_004135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_004140	COG0601	transmembrane transport
AH66_004150	COG2731	YhcH YjgK YiaL family protein
AH66_004160	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AH66_004170	COG0525	valine-tRNA ligase activity
AH66_004175	COG2927	DNA polymerase III (CHI subunit)
AH66_004185	COG0795	lipopolysaccharide-transporting ATPase activity
AH66_004190	COG0795	lipopolysaccharide-transporting ATPase activity
AH66_004200	COG0582	viral genome integration into host DNA
AH66_004235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AH66_004240	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AH66_004245	COG0564	pseudouridine synthase activity
AH66_004255	COG0542	response to heat
AH66_004285	COG5544	Lipoprotein
AH66_004290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AH66_004295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AH66_004295	COG1042	CoA-binding domain protein
AH66_004295	COG0045	succinate-CoA ligase (ADP-forming) activity
AH66_004300	COG3148	PFAM DTW domain containing protein
AH66_004305	COG3118	belongs to the thioredoxin family
AH66_004310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AH66_004315	COG2814	Major facilitator Superfamily
AH66_004320	COG1566	PFAM secretion protein HlyD family protein
AH66_004325	COG1846	Transcriptional regulator
AH66_004335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AH66_004340	COG2814	Major facilitator Superfamily
AH66_004375	COG0765	amino acid transport
AH66_004385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AH66_004400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AH66_004425	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
AH66_004435	COG1960	acyl-CoA dehydrogenase activity
AH66_004445	COG0121	glutamine amidotransferase
AH66_004450	COG3034	peptidoglycan biosynthetic process
AH66_004460	COG1805	sodium ion transport
AH66_004465	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AH66_004485	COG1477	protein flavinylation
AH66_004505	COG2195	Cleaves the N-terminal amino acid of tripeptides
AH66_004510	COG0583	DNA-binding transcription factor activity
AH66_004560	COG2226	methyltransferase
AH66_004585	COG1940	carbohydrate kinase activity
AH66_004600	COG0419	ATPase involved in DNA repair
AH66_004605	COG0420	3'-5' exonuclease activity
AH66_004610	COG0745	RESPONSE REGULATOR receiver
AH66_004615	COG5002	protein histidine kinase activity
AH66_004635	COG0366	Alpha amylase catalytic
AH66_004660	COG0450	alkyl hydroperoxide reductase
AH66_004680	COG1862	Preprotein translocase
AH66_004685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AH66_004690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AH66_004715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AH66_004715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AH66_004730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AH66_004735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AH66_004750	COG0142	geranyltranstransferase activity
AH66_004765	COG0693	protein deglycase activity
AH66_004770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AH66_004780	COG2814	Major facilitator Superfamily
AH66_004790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AH66_004795	COG1845	cytochrome c oxidase, subunit III
AH66_004800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AH66_004805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AH66_004815	COG2223	nitrite transmembrane transporter activity
AH66_004820	COG3056	Lipoprotein
AH66_004825	COG0271	Belongs to the BolA IbaG family
AH66_004845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AH66_004850	COG0776	regulation of translation
AH66_004855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AH66_004860	COG1555	photosystem II stabilization
AH66_004865	COG0824	Thioesterase
AH66_004875	COG4533	DNA binding
AH66_004890	COG1522	sequence-specific DNA binding
AH66_004895	COG1132	(ABC) transporter
AH66_004900	COG1132	(ABC) transporter
AH66_004905	COG0347	Belongs to the P(II) protein family
AH66_004910	COG0004	ammonium transporteR
AH66_004915	COG1946	Acyl-CoA thioesterase
AH66_004920	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AH66_004925	COG3695	enzyme binding
AH66_004950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AH66_004960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_004965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_004970	COG1309	transcriptional regulator
AH66_004975	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AH66_004980	COG1196	nuclear chromosome segregation
AH66_004980	COG3264	Mechanosensitive ion channel
AH66_005015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AH66_005045	COG0543	2 iron, 2 sulfur cluster binding
AH66_005045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_005065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_005125	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AH66_005130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_005135	COG4651	solute:proton antiporter activity
AH66_005135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AH66_005140	COG2223	nitrite transmembrane transporter activity
AH66_005155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AH66_005180	COG2217	Heavy metal translocating P-type atpase
AH66_005185	COG0789	Transcriptional regulator
AH66_005190	COG1585	Membrane protein implicated in regulation of membrane protease activity
AH66_005195	COG0330	HflC and HflK could
AH66_005200	COG3118	belongs to the thioredoxin family
AH66_005205	COG0300	oxidoreductase activity
AH66_005210	COG2755	lipolytic protein G-D-S-L family
AH66_005215	COG4181	ATPase activity
AH66_005220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AH66_005225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AH66_005230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AH66_005240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AH66_005260	COG1393	Belongs to the ArsC family
AH66_005265	COG4783	chaperone-mediated protein folding
AH66_005270	COG0628	permease
AH66_005280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AH66_005285	COG2716	regulation of RNA biosynthetic process
AH66_005295	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AH66_005310	COG2321	neutral zinc metallopeptidase
AH66_005330	COG1876	peptidase activity
AH66_005340	COG1393	Belongs to the ArsC family
AH66_005355	COG1175	transmembrane transport
AH66_005360	COG3842	ATPase activity
AH66_005370	COG3119	arylsulfatase activity
AH66_005375	COG0641	radical SAM
AH66_005380	COG1988	membrane-bound metal-dependent
AH66_005390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_005400	COG2197	response regulator
AH66_005405	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_005405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_005410	COG3062	negative regulation of establishment of protein localization
AH66_005420	COG3043	anaerobic respiration
AH66_005425	COG3005	denitrification pathway
AH66_005465	COG3111	PFAM Bacterial OB fold (BOF) protein
AH66_005475	COG2837	iron assimilation
AH66_005480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AH66_005500	COG2731	YhcH YjgK YiaL family protein
AH66_005505	COG1737	Transcriptional regulator
AH66_005515	COG4150	thiosulfate binding
AH66_005520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AH66_005525	COG4208	sulfate ABC transporter
AH66_005530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AH66_005545	COG0745	RESPONSE REGULATOR receiver
AH66_005550	COG3850	Histidine kinase
AH66_005550	COG5002	protein histidine kinase activity
AH66_005560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AH66_005580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AH66_005595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_005600	COG0745	RESPONSE REGULATOR receiver
AH66_005605	COG2205	protein histidine kinase activity
AH66_005625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_005635	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AH66_005650	COG3530	Putative quorum-sensing-regulated virulence factor
AH66_005715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AH66_005730	COG0667	Aldo Keto reductase
AH66_005755	COG0436	Aminotransferase
AH66_005760	COG3038	cytochrome b561
AH66_005790	COG3381	protein complex oligomerization
AH66_005795	COG3302	dmso reductase anchor subunit
AH66_005800	COG0437	4 iron, 4 sulfur cluster binding
AH66_005805	COG0243	molybdopterin cofactor binding
AH66_005840	COG2951	lytic endotransglycosylase activity
AH66_005900	COG3121	Chaperone
AH66_005905	COG3188	usher protein
AH66_005910	COG3328	transposase activity
AH66_005915	COG3188	usher protein
AH66_005990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_005995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_006000	COG1120	ATPase activity
AH66_006025	COG4160	amino acid transport
AH66_006030	COG4215	(ABC) transporter
AH66_006035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_006040	COG1126	abc transporter atp-binding protein
AH66_006045	COG1605	Chorismate mutase
AH66_006055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_006060	COG0702	epimerase
AH66_006065	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AH66_006075	COG0028	Belongs to the TPP enzyme family
AH66_006080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_006090	COG2431	L-lysine efflux transmembrane transporter activity
AH66_006095	COG3593	DNA synthesis involved in DNA repair
AH66_006100	COG2990	Protein conserved in bacteria
AH66_006105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_006115	COG1278	Cold shock
AH66_006125	COG0542	response to heat
AH66_006135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AH66_006145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AH66_006155	COG0492	ferredoxin-NADP+ reductase activity
AH66_006165	COG1674	ftsk spoiiie
AH66_006165	COG3107	peptidoglycan biosynthetic process
AH66_006175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AH66_006190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AH66_006200	COG1882	Formate acetyltransferase
AH66_006205	COG2116	formate transmembrane transporter activity
AH66_006210	COG1944	ATP diphosphatase activity
AH66_006215	COG0252	asparaginase activity
AH66_006220	COG5295	Hep Hag repeat protein
AH66_006220	COG5295	Hep Hag repeat protein
AH66_006245	COG0539	negative regulation of cytoplasmic translation
AH66_006255	COG2333	competence protein COMEC
AH66_006255	COG0658	competence protein
AH66_006270	COG5383	Protein conserved in bacteria
AH66_006275	COG1278	Cold shock
AH66_006290	COG3173	Aminoglycoside phosphotransferase
AH66_006295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AH66_006320	COG2989	Protein conserved in bacteria
AH66_006325	COG3108	Peptidase M15
AH66_006330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AH66_006340	COG1448	Aminotransferase
AH66_006360	COG0308	aminopeptidase N
AH66_006375	COG0633	Ferredoxin
AH66_006375	COG3217	Mosc domain protein beta barrel domain protein
AH66_006385	COG0488	(ABC) transporter
AH66_006390	COG2995	paraquat-inducible protein a
AH66_006395	COG3008	intermembrane lipid transfer
AH66_006395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AH66_006400	COG3009	Protein conserved in bacteria
AH66_006405	COG3130	regulation of translation
AH66_006445	COG1067	ATP-dependent peptidase activity
AH66_006470	COG3070	regulator of competence-specific genes
AH66_006475	COG1289	transmembrane transporter activity
AH66_006480	COG3304	Inner membrane component domain
AH66_006485	COG0210	DNA helicase
AH66_006500	COG1832	CoA-binding protein
AH66_006520	COG2920	part of a sulfur-relay system
AH66_006545	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_006555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AH66_006560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AH66_006565	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_006570	COG3425	synthase
AH66_006580	COG1024	Enoyl-CoA hydratase
AH66_006585	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_006595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AH66_006600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AH66_006730	COG0488	(ABC) transporter
AH66_006740	COG3328	transposase activity
AH66_006750	COG0303	'Molybdopterin
AH66_006760	COG1136	(ABC) transporter
AH66_006790	COG0583	DNA-binding transcription factor activity
AH66_006795	COG0477	Major facilitator Superfamily
AH66_006805	COG2311	Membrane
AH66_006820	COG4211	Belongs to the binding-protein-dependent transport system permease family
AH66_006825	COG2949	membrane
AH66_006840	COG1346	cytolysis
AH66_006850	COG2814	Major facilitator Superfamily
AH66_006890	COG0489	protein tyrosine kinase activity
AH66_006905	COG2982	Protein involved in outer membrane biogenesis
AH66_006910	COG1253	flavin adenine dinucleotide binding
AH66_006915	COG4114	ferric iron reductase
AH66_006920	COG0076	glutamate decarboxylase activity
AH66_006925	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AH66_006940	COG1120	ATPase activity
AH66_006945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_006950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_006955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AH66_006970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AH66_006975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AH66_006985	COG0140	phosphoribosyl-ATP diphosphatase activity
AH66_006985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AH66_007005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AH66_007005	COG0131	Imidazoleglycerol-phosphate dehydratase
AH66_007015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AH66_007030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_007045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_007050	COG1129	ABC transporter
AH66_007055	COG1129	ABC transporter
AH66_007060	COG0371	Dehydrogenase
AH66_007065	COG0531	amino acid
AH66_007075	COG2925	Exonuclease
AH66_007090	COG3328	transposase activity
AH66_007095	COG1388	LysM domain
AH66_007095	COG1470	cell adhesion involved in biofilm formation
AH66_007100	COG2271	Major facilitator Superfamily
AH66_007105	COG3011	Protein conserved in bacteria
AH66_007110	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_007120	COG4948	Mandelate Racemase Muconate Lactonizing
AH66_007135	COG0534	Mate efflux family protein
AH66_007155	COG3122	Protein conserved in bacteria
AH66_007180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AH66_007200	COG2223	nitrite transmembrane transporter activity
AH66_007205	COG3328	transposase activity
AH66_007225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AH66_007235	COG3328	transposase activity
AH66_007240	COG1530	ribonuclease E activity
AH66_007245	COG0564	pseudouridine synthase activity
AH66_007255	COG0424	maF-like protein
AH66_007260	COG1399	metal-binding, possibly nucleic acid-binding protein
AH66_007265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AH66_007295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AH66_007305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AH66_007310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AH66_007320	COG0470	DNA polymerase III
AH66_007325	COG0084	hydrolase, TatD family'
AH66_007330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_007330	COG1263	PTS System
AH66_007340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AH66_007345	COG0537	adenosine 5'-monophosphoramidase activity
AH66_007350	COG5633	Lipoprotein
AH66_007365	COG1472	Belongs to the glycosyl hydrolase 3 family
AH66_007375	COG1252	NADH dehydrogenase
AH66_007390	COG3328	transposase activity
AH66_007405	COG3134	Outer membrane lipoprotein
AH66_007410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AH66_007415	COG4591	ABC-type transport system involved in lipoprotein release permease component
AH66_007425	COG4591	ABC-type transport system involved in lipoprotein release permease component
AH66_007430	COG1940	carbohydrate kinase activity
AH66_007450	COG2850	peptidyl-arginine hydroxylation
AH66_007460	COG0745	RESPONSE REGULATOR receiver
AH66_007470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AH66_007490	COG1187	pseudouridine synthase activity
AH66_007495	COG0538	isocitrate dehydrogenase activity
AH66_007510	COG0840	transmembrane signaling receptor activity
AH66_007515	COG0702	epimerase
AH66_007520	COG1733	regulation of RNA biosynthetic process
AH66_007545	COG1522	sequence-specific DNA binding
AH66_007560	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_007560	COG3321	synthase
AH66_007560	COG0604	alcohol dehydrogenase
AH66_007595	COG1285	pathogenesis
AH66_007620	COG1360	Flagellar Motor Protein
AH66_007625	COG0643	Histidine kinase
AH66_007625	COG2198	Histidine kinase
AH66_007630	COG0835	chemotaxis
AH66_007635	COG2271	Major facilitator Superfamily
AH66_007640	COG0251	oxidation-reduction process
AH66_007650	COG2964	Protein conserved in bacteria
AH66_007670	COG0840	transmembrane signaling receptor activity
AH66_007680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AH66_007690	COG0745	RESPONSE REGULATOR receiver
AH66_007695	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AH66_007700	COG3023	N-Acetylmuramoyl-L-alanine amidase
AH66_007710	COG5295	Hep Hag repeat protein
AH66_007720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AH66_007775	COG3121	Chaperone
AH66_007800	COG2995	paraquat-inducible protein a
AH66_007805	COG1956	GAF domain-containing protein
AH66_007815	COG0793	Belongs to the peptidase S41A family
AH66_007825	COG3539	Fimbrial protein
AH66_007830	COG3121	Chaperone
AH66_007845	COG3121	Chaperone
AH66_007850	COG2814	Major facilitator Superfamily
AH66_007855	COG0823	Involved in the tonB-independent uptake of proteins
AH66_007865	COG3023	N-Acetylmuramoyl-L-alanine amidase
AH66_007870	COG1823	symporter activity
AH66_007875	COG1988	membrane-bound metal-dependent
AH66_007880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AH66_007885	COG1653	transport
AH66_007890	COG3842	ATPase activity
AH66_007895	COG0395	ABC-type sugar transport system, permease component
AH66_007900	COG1175	transmembrane transport
AH66_007910	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_007920	COG1917	Cupin 2, conserved barrel domain protein
AH66_007925	COG3328	transposase activity
AH66_007970	COG1132	(ABC) transporter
AH66_007980	COG2207	Transcriptional regulator
AH66_008015	COG1113	amino acid transport
AH66_008035	COG1496	oxidoreductase activity
AH66_008040	COG2226	methyltransferase
AH66_008050	COG5002	protein histidine kinase activity
AH66_008050	COG3447	MASE1 domain protein
AH66_008050	COG5001	Diguanylate cyclase
AH66_008070	COG3716	PTS system mannose fructose sorbose family IID component
AH66_008075	COG3715	PTS system
AH66_008080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_008080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_008085	COG1253	flavin adenine dinucleotide binding
AH66_008090	COG1846	Transcriptional regulator
AH66_008105	COG1012	belongs to the aldehyde dehydrogenase family
AH66_008110	COG3384	dioxygenase
AH66_008120	COG3971	2-oxopent-4-enoate hydratase activity
AH66_008135	COG2368	4-hydroxyphenylacetate
AH66_008140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AH66_008145	COG1760	l-serine dehydratase
AH66_008170	COG0513	Belongs to the DEAD box helicase family
AH66_008175	COG3141	response to X-ray
AH66_008190	COG1770	oligopeptidase
AH66_008205	COG1528	Iron-storage protein
AH66_008210	COG2372	response to copper ion
AH66_008235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AH66_008240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AH66_008265	COG3418	PFAM FlgN family protein
AH66_008270	COG2747	anti-sigma28 factor FlgM
AH66_008280	COG1815	bacterial-type flagellum-dependent cell motility
AH66_008285	COG1558	bacterial-type flagellum-dependent cell motility
AH66_008325	COG1256	bacterial-type flagellum assembly
AH66_008335	COG2390	Transcriptional regulator
AH66_008340	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_008340	COG3347	Dehydrogenase
AH66_008345	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_008355	COG1129	ABC transporter
AH66_008360	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_008365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_008385	COG1987	bacterial-type flagellum assembly
AH66_008410	COG1580	Controls the rotational direction of flagella during chemotaxis
AH66_008425	COG1157	protein secretion by the type III secretion system
AH66_008445	COG1677	Flagellar hook-basal body complex protein FliE
AH66_008465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AH66_008470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AH66_008475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AH66_008505	COG1191	sigma factor activity
AH66_008520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_008525	COG0765	amino acid transport
AH66_008530	COG1126	abc transporter atp-binding protein
AH66_008545	COG0506	proline dehydrogenase activity
AH66_008545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AH66_008545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AH66_008560	COG0672	)-iron permease
AH66_008565	COG2822	iron ion transport
AH66_008585	COG1113	amino acid transport
AH66_008605	COG3136	membrane protein required for alginate biosynthesis
AH66_008615	COG2197	response regulator
AH66_008740	COG2188	Transcriptional regulator
AH66_008745	COG0673	inositol 2-dehydrogenase activity
AH66_008755	COG1175	transmembrane transport
AH66_008760	COG0395	ABC-type sugar transport system, permease component
AH66_008765	COG3842	ATPase activity
AH66_008815	COG0402	S-adenosylhomocysteine deaminase activity
AH66_008830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AH66_008835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AH66_008840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_008885	COG3328	transposase activity
AH66_008905	COG0500	methyltransferase
AH66_008950	COG5002	protein histidine kinase activity
AH66_009000	COG0012	GTP binding
AH66_009015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AH66_009040	COG2890	protein-(glutamine-N5) methyltransferase activity
AH66_009065	COG0659	secondary active sulfate transmembrane transporter activity
AH66_009100	COG3833	ABC-type maltose transport systems, permease component
AH66_009105	COG1176	ABC-type spermidine putrescine transport system, permease component I
AH66_009125	COG0584	glycerophosphoryl diester phosphodiesterase
AH66_009130	COG1940	carbohydrate kinase activity
AH66_009145	COG3381	protein complex oligomerization
AH66_009160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AH66_009170	COG0728	peptidoglycan biosynthetic process
AH66_009190	COG3102	Protein conserved in bacteria
AH66_009210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AH66_009215	COG1801	Protein of unknown function DUF72
AH66_009225	COG0494	nUDIX hydrolase
AH66_009250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AH66_009260	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AH66_009265	COG0739	heme binding
AH66_009270	COG1560	Kdo2-lipid A biosynthetic process
AH66_009280	COG0469	pyruvate kinase activity
AH66_009285	COG1737	Transcriptional regulator
AH66_009290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AH66_009295	COG0800	Aldolase
AH66_009310	COG0251	oxidation-reduction process
AH66_009315	COG1199	ATP-dependent helicase activity
AH66_009325	COG3065	identical protein binding
AH66_009335	COG0318	PFAM AMP-dependent synthetase and ligase
AH66_009340	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AH66_009345	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AH66_009350	COG2894	cell division
AH66_009365	COG2951	lytic endotransglycosylase activity
AH66_009370	COG0179	Fumarylacetoacetate (FAA) hydrolase
AH66_009380	COG0582	viral genome integration into host DNA
AH66_009480	COG3328	transposase activity
AH66_009645	COG3328	transposase activity
AH66_009655	COG1104	cysteine desulfurase activity
AH66_009685	COG2719	SpoVR family
AH66_009695	COG2814	Major facilitator Superfamily
AH66_009705	COG0583	DNA-binding transcription factor activity
AH66_009720	COG2766	serine protein kinase
AH66_009725	COG3713	MltA-interacting MipA family protein
AH66_009745	COG3139	Protein of unknown function (DUF1315)
AH66_009750	COG1335	isochorismatase
AH66_009755	COG0252	asparaginase activity
AH66_009760	COG0616	signal peptide processing
AH66_009765	COG0778	Nitroreductase
AH66_009770	COG0709	Synthesizes selenophosphate from selenide and ATP
AH66_009775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AH66_009785	COG0494	nUDIX hydrolase
AH66_009790	COG0708	Exodeoxyribonuclease III
AH66_009795	COG0583	DNA-binding transcription factor activity
AH66_009815	COG3328	transposase activity
AH66_009820	COG0788	formyltetrahydrofolate deformylase activity
AH66_009830	COG0745	RESPONSE REGULATOR receiver
AH66_009860	COG1012	belongs to the aldehyde dehydrogenase family
AH66_009860	COG1454	alcohol dehydrogenase
AH66_009865	COG2095	MarC family integral membrane protein
AH66_009875	COG0601	transmembrane transport
AH66_009880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_009885	COG0444	Belongs to the ABC transporter superfamily
AH66_009890	COG4608	Belongs to the ABC transporter superfamily
AH66_009935	COG2350	Protein conserved in bacteria
AH66_009940	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AH66_009945	COG3328	transposase activity
AH66_009980	COG3047	cAMP biosynthetic process
AH66_010000	COG0135	phosphoribosylanthranilate isomerase activity
AH66_010000	COG0134	indole-3-glycerol-phosphate synthase activity
AH66_010010	COG0512	Glutamine amidotransferase of anthranilate synthase
AH66_010030	COG0009	L-threonylcarbamoyladenylate synthase
AH66_010035	COG1187	pseudouridine synthase activity
AH66_010045	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_010050	COG0616	signal peptide processing
AH66_010070	COG0583	DNA-binding transcription factor activity
AH66_010080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AH66_010090	COG0671	phosphoesterase, PA-phosphatase related
AH66_010095	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AH66_010100	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AH66_010115	COG0023	Translation Initiation Factor
AH66_010135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AH66_010140	COG2879	small protein
AH66_010145	COG1966	Carbon starvation protein
AH66_010155	COG2271	Major facilitator Superfamily
AH66_010160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_010165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AH66_010175	COG4659	FMN binding
AH66_010180	COG4658	electron transport chain
AH66_010185	COG2207	Transcriptional regulator
AH66_010185	COG3708	Transcriptional regulator
AH66_010215	COG1132	(ABC) transporter
AH66_010225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_010230	COG2274	protein secretion by the type I secretion system
AH66_010245	COG1879	ABC-type sugar transport system periplasmic component
AH66_010250	COG1129	ABC transporter
AH66_010255	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_010265	COG0673	inositol 2-dehydrogenase activity
AH66_010270	COG0385	Bile acid
AH66_010305	COG0114	fumarate hydratase activity
AH66_010315	COG2814	Major facilitator Superfamily
AH66_010320	COG0583	DNA-binding transcription factor activity
AH66_010325	COG0583	DNA-binding transcription factor activity
AH66_010330	COG1940	carbohydrate kinase activity
AH66_010335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AH66_010340	COG0038	chloride channel
AH66_010390	COG4128	Pfam Zonular occludens toxin
AH66_010455	COG4128	Pfam Zonular occludens toxin
AH66_010475	COG1609	Transcriptional regulator
AH66_010495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AH66_010500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AH66_010530	COG0028	Belongs to the TPP enzyme family
AH66_010535	COG0440	acetolactate synthase activity
AH66_010540	COG1011	Hydrolase
AH66_010560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AH66_010565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AH66_010570	COG0589	response to stress
AH66_010575	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AH66_010580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AH66_010590	COG0531	amino acid
AH66_010600	COG0745	RESPONSE REGULATOR receiver
AH66_010605	COG2205	protein histidine kinase activity
AH66_010610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AH66_010635	COG3038	cytochrome b561
AH66_010645	COG3591	Belongs to the peptidase S1B family
AH66_010660	COG1643	Atp-dependent helicase
AH66_010670	COG2390	Transcriptional regulator
AH66_010675	COG0246	Mannitol dehydrogenase
AH66_010680	COG3784	Protein of unknown function (DUF1318)
AH66_010690	COG2911	Protein conserved in bacteria
AH66_010695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AH66_010700	COG3187	Heat shock protein
AH66_010705	COG3042	response to heat
AH66_010710	COG1285	pathogenesis
AH66_010720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AH66_010720	COG0674	pyruvate-flavodoxin oxidoreductase activity
AH66_010720	COG1013	pyruvate-flavodoxin oxidoreductase activity
AH66_010720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AH66_010730	COG0657	acetylesterase activity
AH66_010745	COG4166	transmembrane transport
AH66_010750	COG2866	Carboxypeptidase
AH66_010755	COG4948	Mandelate Racemase Muconate Lactonizing
AH66_010760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AH66_010775	COG5642	Protein of unknown function (DUF2384)
AH66_010780	COG5654	RES domain protein
AH66_010790	COG3106	COG3106 Predicted ATPase
AH66_010800	COG1983	PspC domain protein
AH66_010810	COG1842	Phage shock protein A
AH66_010815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AH66_010825	COG4166	transmembrane transport
AH66_010830	COG4168	peptide transport system, permease
AH66_010835	COG4171	peptide transport system, permease
AH66_010845	COG4172	Belongs to the ABC transporter superfamily
AH66_010850	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AH66_010850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AH66_010855	COG3104	oligopeptide transport
AH66_010880	COG0625	glutathione transferase activity
AH66_010900	COG3895	Periplasmic Protein
AH66_010915	COG3313	Fe-S protein
AH66_010920	COG2194	sulfuric ester hydrolase activity
AH66_010925	COG1309	transcriptional regulator
AH66_010930	COG1902	pentaerythritol trinitrate reductase activity
AH66_010940	COG0346	lactoylglutathione lyase activity
AH66_010945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AH66_010955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AH66_010960	COG0791	NLP P60 protein
AH66_010980	COG0583	DNA-binding transcription factor activity
AH66_010985	COG2814	Major facilitator Superfamily
AH66_010990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AH66_010995	COG0307	riboflavin synthase, alpha
AH66_011045	COG1376	ErfK ybiS ycfS ynhG family protein
AH66_011045	COG1388	LysM domain
AH66_011060	COG0719	Fe-S assembly protein
AH66_011065	COG0396	ATPase activity
AH66_011070	COG0719	Fe-S assembly protein
AH66_011075	COG0316	Belongs to the HesB IscA family
AH66_011080	COG2050	protein possibly involved in aromatic compounds catabolism
AH66_011085	COG0277	FAD linked oxidase domain protein
AH66_011085	COG0247	lactate metabolic process
AH66_011090	COG0628	permease
AH66_011100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AH66_011100	COG0574	Belongs to the PEP-utilizing enzyme family
AH66_011125	COG0791	NLP P60 protein
AH66_011175	COG0386	Belongs to the glutathione peroxidase family
AH66_011190	COG0776	regulation of translation
AH66_011195	COG0072	phenylalanine-tRNA ligase activity
AH66_011195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AH66_011230	COG4249	Peptidase C14 caspase catalytic subunit p20
AH66_011250	COG0803	Belongs to the bacterial solute-binding protein 9 family
AH66_011255	COG1121	(ABC) transporter
AH66_011260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AH66_011265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AH66_011275	COG3001	Fructosamine kinase
AH66_011285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_011290	COG3328	transposase activity
AH66_011310	COG0628	permease
AH66_011330	COG3916	Acyl-homoserine-lactone synthase
AH66_011335	COG2771	luxR family
AH66_011340	COG0583	DNA-binding transcription factor activity
AH66_011350	COG0477	Major facilitator Superfamily
AH66_011360	COG0667	Aldo Keto reductase
AH66_011385	COG1203	CRISPR-associated helicase, Cas3
AH66_011390	COG1518	maintenance of DNA repeat elements
AH66_011395	COG0668	transmembrane transport
AH66_011415	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AH66_011420	COG0395	ABC-type sugar transport system, permease component
AH66_011435	COG1609	Transcriptional regulator
AH66_011445	COG3842	ATPase activity
AH66_011455	COG3210	domain, Protein
AH66_011495	COG3210	domain, Protein
AH66_011500	COG2831	hemolysin activation secretion protein
AH66_011505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_011510	COG4638	Rieske (2fe-2S)
AH66_011515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AH66_011525	COG0473	3-isopropylmalate dehydrogenase activity
AH66_011530	COG0583	DNA-binding transcription factor activity
AH66_011535	COG1609	Transcriptional regulator
AH66_011540	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_011545	COG1129	ABC transporter
AH66_011550	COG1879	ABC-type sugar transport system periplasmic component
AH66_011555	COG1063	alcohol dehydrogenase
AH66_011575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AH66_011605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_011610	COG0765	amino acid transport
AH66_011615	COG1126	abc transporter atp-binding protein
AH66_011650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AH66_011665	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AH66_011680	COG1169	isochorismate synthase
AH66_011690	COG4575	ribosome binding
AH66_011695	COG0129	dihydroxy-acid dehydratase activity
AH66_011710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AH66_011715	COG1609	Transcriptional regulator
AH66_011720	COG1649	PFAM Uncharacterised BCR, COG1649
AH66_011725	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_011730	COG3265	gluconokinase activity
AH66_011735	COG2731	YhcH YjgK YiaL family protein
AH66_011750	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AH66_011755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AH66_011765	COG0839	Belongs to the complex I subunit 6 family
AH66_011780	COG1034	ATP synthesis coupled electron transport
AH66_011810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AH66_011820	COG0583	DNA-binding transcription factor activity
AH66_011825	COG0436	Aminotransferase
AH66_011840	COG0471	metal ion transport
AH66_011840	COG0490	domain, Protein
AH66_011845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_011865	COG0857	belongs to the CobB CobQ family
AH66_011865	COG0280	phosphate acetyltransferase
AH66_011870	COG1609	Transcriptional regulator
AH66_011885	COG3328	transposase activity
AH66_011890	COG4953	penicillin-binding protein 1C
AH66_011895	COG2373	Large extracellular alpha-helical protein
AH66_011915	COG3962	Belongs to the TPP enzyme family
AH66_011930	COG1129	ABC transporter
AH66_011935	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_011940	COG0673	inositol 2-dehydrogenase activity
AH66_011945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_011955	COG3718	enzyme involved in inositol metabolism
AH66_011965	COG5265	(ABC) transporter
AH66_011990	COG2197	response regulator
AH66_012005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AH66_012010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AH66_012030	COG1686	Belongs to the peptidase S11 family
AH66_012035	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AH66_012040	COG0772	Belongs to the SEDS family
AH66_012045	COG0768	penicillin binding
AH66_012055	COG0799	negative regulation of ribosome biogenesis
AH66_012065	COG1466	dna polymerase III delta subunit
AH66_012080	COG2888	peptidyl-tyrosine sulfation
AH66_012085	COG1126	abc transporter atp-binding protein
AH66_012090	COG0765	amino acid transport
AH66_012095	COG0765	amino acid transport
AH66_012110	COG4535	Mg2 and Co2 transporter CorC
AH66_012120	COG1702	phosphate starvation-inducible protein PhoH
AH66_012125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AH66_012130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AH66_012160	COG0367	asparagine synthase
AH66_012165	COG0647	UMP catabolic process
AH66_012170	COG1846	Transcriptional regulator
AH66_012170	COG1940	carbohydrate kinase activity
AH66_012175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AH66_012185	COG2190	(PTS) system
AH66_012185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_012185	COG1263	PTS System
AH66_012210	COG0735	belongs to the Fur family
AH66_012225	COG0596	Alpha beta hydrolase
AH66_012235	COG0582	viral genome integration into host DNA
AH66_012270	COG2113	Glycine betaine
AH66_012275	COG4176	ABC-type proline glycine betaine transport system permease component
AH66_012280	COG4175	Glycine betaine
AH66_012285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AH66_012320	COG3328	transposase activity
AH66_012330	COG1278	Cold shock
AH66_012335	COG0747	negative chemotaxis
AH66_012345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_012350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AH66_012355	COG1124	(ABC) transporter
AH66_012360	COG0831	urea catabolic process
AH66_012385	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AH66_012395	COG4413	Urea transporter
AH66_012400	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AH66_012410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AH66_012420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AH66_012430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AH66_012435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AH66_012440	COG1447	Phosphotransferase system cellobiose-specific component IIA
AH66_012445	COG1917	Cupin 2, conserved barrel domain protein
AH66_012445	COG2169	Transcriptional regulator
AH66_012460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AH66_012465	COG0033	Phosphoglucomutase
AH66_012480	COG0745	RESPONSE REGULATOR receiver
AH66_012485	COG2205	protein histidine kinase activity
AH66_012520	COG3272	Protein of unknown function (DUF1722)
AH66_012530	COG5212	phosphodiesterase
AH66_012535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AH66_012550	COG1984	allophanate hydrolase subunit 2
AH66_012595	COG0513	Belongs to the DEAD box helicase family
AH66_012605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AH66_012620	COG3026	antisigma factor binding
AH66_012625	COG3086	response to oxidative stress
AH66_012710	COG2824	Alkylphosphonate utilization operon protein PhnA
AH66_012720	COG1704	LemA family
AH66_012740	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AH66_012745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AH66_012750	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AH66_012760	COG1138	Cytochrome C-type biogenesis protein
AH66_012765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AH66_012770	COG3088	subunit of a heme lyase
AH66_012770	COG4235	cytochrome complex assembly
AH66_012775	COG4235	cytochrome complex assembly
AH66_012775	COG3088	subunit of a heme lyase
AH66_012790	COG3691	Protein conserved in bacteria
AH66_012805	COG2062	phosphohistidine phosphatase, SixA
AH66_012815	COG2890	protein-(glutamine-N5) methyltransferase activity
AH66_012825	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AH66_012830	COG0730	response to heat
AH66_012835	COG3101	peptidyl-lysine hydroxylation
AH66_012850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AH66_012855	COG1794	racemase activity, acting on amino acids and derivatives
AH66_012870	COG0697	spore germination
AH66_012890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AH66_012900	COG0586	Pfam SNARE associated Golgi protein
AH66_012910	COG0285	dihydrofolate synthase activity
AH66_012915	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AH66_012920	COG1286	toxin biosynthetic process
AH66_012925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AH66_012935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_012940	COG4215	(ABC) transporter
AH66_012945	COG4160	amino acid transport
AH66_012950	COG4598	ABC transporter
AH66_012955	COG1090	epimerase
AH66_012970	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AH66_012975	COG3037	sugar-specific permease SgaT UlaA
AH66_012980	COG3328	transposase activity
AH66_012985	COG4953	penicillin-binding protein 1C
AH66_012990	COG3423	Transcriptional regulator
AH66_013045	COG3328	transposase activity
AH66_013060	COG1472	Belongs to the glycosyl hydrolase 3 family
AH66_013070	COG0656	L-ascorbic acid biosynthetic process
AH66_013075	COG0667	Aldo Keto reductase
AH66_013105	COG2453	phosphatase
AH66_013105	COG0671	phosphoesterase, PA-phosphatase related
AH66_013110	COG2267	carboxylic ester hydrolase activity
AH66_013120	COG4589	Belongs to the CDS family
AH66_013125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AH66_013135	COG0582	viral genome integration into host DNA
AH66_013170	COG2501	S4 domain
AH66_013190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AH66_013195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AH66_013210	COG0581	inorganic phosphate transmembrane transporter activity
AH66_013220	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AH66_013235	COG2239	Acts as a magnesium transporter
AH66_013240	COG0443	Heat shock 70 kDa protein
AH66_013245	COG1177	transmembrane transport
AH66_013250	COG1176	ABC-type spermidine putrescine transport system, permease component I
AH66_013260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AH66_013270	COG3842	ATPase activity
AH66_013300	COG0745	RESPONSE REGULATOR receiver
AH66_013305	COG3422	double-strand break repair
AH66_013310	COG0826	peptidase U32
AH66_013335	COG0351	phosphomethylpyrimidine kinase
AH66_013350	COG3328	transposase activity
AH66_013395	COG0517	IMP dehydrogenase activity
AH66_013395	COG0516	GMP reductase activity
AH66_013405	COG1645	bacterial-type flagellum-dependent swarming motility
AH66_013420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AH66_013425	COG2976	Protein conserved in bacteria
AH66_013465	COG3468	outer membrane autotransporter barrel domain protein
AH66_013470	COG3468	outer membrane autotransporter barrel domain protein
AH66_013495	COG2975	iron-sulfur cluster assembly
AH66_013500	COG0633	Ferredoxin
AH66_013505	COG0443	Heat shock 70 kDa protein
AH66_013520	COG0822	iron-sulfur transferase activity
AH66_013525	COG1104	cysteine desulfurase activity
AH66_013550	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AH66_013555	COG3683	transport system, periplasmic component
AH66_013560	COG3711	transcriptional antiterminator
AH66_013565	COG2814	Major facilitator Superfamily
AH66_013585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_013585	COG1017	nitric oxide dioxygenase activity
AH66_013595	COG0347	Belongs to the P(II) protein family
AH66_013600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AH66_013600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AH66_013605	COG2204	response regulator
AH66_013610	COG3170	Tfp pilus assembly protein FimV
AH66_013615	COG2205	protein histidine kinase activity
AH66_013660	COG0560	Phosphoserine phosphatase
AH66_013670	COG1737	Transcriptional regulator
AH66_013675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_013690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AH66_013720	COG1177	transmembrane transport
AH66_013725	COG1176	ABC-type spermidine putrescine transport system, permease component I
AH66_013730	COG3842	ATPase activity
AH66_013735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AH66_013765	COG0671	phosphoesterase, PA-phosphatase related
AH66_013775	COG1349	DNA-binding transcription factor activity
AH66_013780	COG0814	amino acid
AH66_013785	COG1686	Belongs to the peptidase S11 family
AH66_013790	COG2011	ABC-type metal ion transport system permease component
AH66_013815	COG0625	glutathione transferase activity
AH66_013820	COG4771	TonB-dependent receptor
AH66_013830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_013840	COG0833	amino acid
AH66_013845	COG0583	DNA-binding transcription factor activity
AH66_013850	COG2855	membrane
AH66_013860	COG3188	usher protein
AH66_013865	COG3121	Chaperone
AH66_013880	COG3710	Transcriptional regulator
AH66_013885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_013885	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AH66_013885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_013890	COG1105	Belongs to the carbohydrate kinase PfkB family
AH66_013900	COG0494	nUDIX hydrolase
AH66_013910	COG1129	ABC transporter
AH66_013945	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_013970	COG0246	Mannitol dehydrogenase
AH66_013975	COG2186	Transcriptional regulator
AH66_013980	COG0523	cobalamin synthesis protein
AH66_013985	COG0671	phosphoesterase, PA-phosphatase related
AH66_013990	COG0791	NLP P60 protein
AH66_013995	COG2200	EAL domain
AH66_014000	COG4166	transmembrane transport
AH66_014005	COG4174	ABC transporter (Permease)
AH66_014010	COG4239	(ABC) transporter, permease
AH66_014015	COG4172	Belongs to the ABC transporter superfamily
AH66_014025	COG2814	Major facilitator Superfamily
AH66_014030	COG1187	pseudouridine synthase activity
AH66_014035	COG1061	Type III restriction enzyme res subunit
AH66_014055	COG3082	Protein of unknown function (DUF1414)
AH66_014060	COG3083	sulfuric ester hydrolase activity
AH66_014075	COG3157	Type VI secretion system effector, Hcp
AH66_014095	COG2723	6-phospho-beta-galactosidase activity
AH66_014100	COG1737	Transcriptional regulator
AH66_014120	COG3299	homolog of phage Mu protein gp47
AH66_014160	COG4386	tail sheath protein
AH66_014180	COG3622	Belongs to the hyi family
AH66_014185	COG1349	DNA-binding transcription factor activity
AH66_014195	COG3395	kinase activity
AH66_014235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AH66_014265	COG2223	nitrite transmembrane transporter activity
AH66_014270	COG2198	Histidine kinase
AH66_014270	COG0642	Histidine kinase
AH66_014275	COG0642	Histidine kinase
AH66_014275	COG2198	Histidine kinase
AH66_014285	COG0784	Response regulator, receiver
AH66_014285	COG2205	protein histidine kinase activity
AH66_014310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_014325	COG0814	amino acid
AH66_014350	COG0697	spore germination
AH66_014360	COG1982	Orn Lys Arg decarboxylase major
AH66_014365	COG0531	amino acid
AH66_014370	COG1174	glycine betaine transport
AH66_014375	COG1125	glycine betaine transport
AH66_014380	COG1174	glycine betaine transport
AH66_014390	COG2897	thiosulfate sulfurtransferase activity
AH66_014410	COG1122	ATPase activity
AH66_014430	COG4807	Protein conserved in bacteria
AH66_014445	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AH66_014455	COG2261	transglycosylase associated protein
AH66_014475	COG0277	FAD linked oxidase domain protein
AH66_014480	COG1686	Belongs to the peptidase S11 family
AH66_014490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AH66_014505	COG0670	Belongs to the BI1 family
AH66_014510	COG0314	molybdopterin synthase activity
AH66_014515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AH66_014525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AH66_014530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AH66_014535	COG4628	conserved protein (DUF2132)
AH66_014545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AH66_014555	COG2226	methyltransferase
AH66_014580	COG0561	phosphatase activity
AH66_014590	COG4149	molybdate abc transporter
AH66_014595	COG0725	ABC transporter, periplasmic molybdate-binding protein
AH66_014605	COG3585	molybdate ion transport
AH66_014605	COG2005	Transcriptional regulator
AH66_014610	COG1119	ATPase activity
AH66_014620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AH66_014625	COG1085	galactose-1-phosphate uridylyltransferase
AH66_014640	COG2017	converts alpha-aldose to the beta-anomer
AH66_014655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AH66_014670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AH66_014675	COG1230	cation diffusion facilitator family transporter
AH66_014705	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AH66_014710	COG2885	chlorophyll binding
AH66_014720	COG3064	Membrane
AH66_014720	COG3064	Membrane
AH66_014725	COG0848	biopolymer transport protein
AH66_014730	COG0811	peptide transport
AH66_014735	COG0824	Thioesterase
AH66_014740	COG3790	cyd operon protein YbgE
AH66_014745	COG4890	Cyd operon protein YbgT
AH66_014750	COG1294	oxidase, subunit
AH66_014755	COG1271	oxidase subunit
AH66_014760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AH66_014770	COG0508	dehydrogenase complex catalyzes the overall conversion of
AH66_014775	COG0567	Dehydrogenase, E1 component
AH66_014785	COG1053	succinate dehydrogenase
AH66_014790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AH66_014795	COG2009	succinate dehydrogenase
AH66_014810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AH66_014815	COG0497	DNA recombination
AH66_014820	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AH66_014830	COG2867	negative regulation of translational initiation
AH66_014850	COG0582	viral genome integration into host DNA
AH66_014900	COG3657	addiction module killer protein
AH66_014925	COG1953	Uracil, thiamine, allantoin
AH66_014945	COG2226	methyltransferase
AH66_014950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AH66_014955	COG1388	LysM domain
AH66_014955	COG0741	lytic transglycosylase activity
AH66_014970	COG0656	L-ascorbic acid biosynthetic process
AH66_015005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AH66_015015	COG2011	ABC-type metal ion transport system permease component
AH66_015020	COG1464	Belongs to the NlpA lipoprotein family
AH66_015030	COG1720	tRNA m6t6A37 methyltransferase activity
AH66_015040	COG3015	lipoprotein NlpE involved in copper resistance
AH66_015050	COG4681	YaeQ
AH66_015060	COG4568	rho-dependent transcription termination
AH66_015070	COG0037	tRNA processing
AH66_015075	COG0346	lactoylglutathione lyase activity
AH66_015085	COG0587	DNA-directed DNA polymerase activity
AH66_015110	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AH66_015125	COG0750	zinc metalloprotease
AH66_015130	COG0575	Belongs to the CDS family
AH66_015190	COG0564	pseudouridine synthase activity
AH66_015195	COG3098	single-species biofilm formation
AH66_015215	COG1611	Belongs to the LOG family
AH66_015230	COG2363	Small membrane protein
AH66_015235	COG0583	DNA-binding transcription factor activity
AH66_015245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AH66_015250	COG2166	iron-sulfur cluster assembly
AH66_015255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AH66_015260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AH66_015275	COG0860	N-Acetylmuramoyl-L-alanine amidase
AH66_015285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AH66_015290	COG1074	ATP-dependent DNA helicase activity
AH66_015300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AH66_015340	COG4771	TonB-dependent receptor
AH66_015345	COG2195	Cleaves the N-terminal amino acid of tripeptides
AH66_015350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AH66_015395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_015405	COG5001	Diguanylate cyclase
AH66_015415	COG2211	Major facilitator Superfamily
AH66_015465	COG2771	luxR family
AH66_015470	COG3916	Acyl-homoserine-lactone synthase
AH66_015590	COG1982	Orn Lys Arg decarboxylase major
AH66_015595	COG1879	ABC-type sugar transport system periplasmic component
AH66_015600	COG1129	ABC transporter
AH66_015605	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_015610	COG4774	siderophore transport
AH66_015630	COG1194	a g-specific adenine glycosylase
AH66_015640	COG3171	Protein conserved in bacteria
AH66_015655	COG3064	Membrane
AH66_015655	COG1073	alpha beta
AH66_015655	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AH66_015660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AH66_015665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AH66_015675	COG0762	integral membrane protein
AH66_015680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AH66_015685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AH66_015690	COG2805	Type II/IV secretion system protein
AH66_015700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AH66_015715	COG0189	ligase activity
AH66_015720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AH66_015725	COG2356	endonuclease I
AH66_015730	COG3091	SprT-like family
AH66_015740	COG1166	arginine decarboxylase activity
AH66_015765	COG0501	Belongs to the peptidase M48B family
AH66_015770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AH66_015790	COG0191	fructose-bisphosphate aldolase activity
AH66_015825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AH66_015835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AH66_015855	COG0006	proline dipeptidase activity
AH66_015860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AH66_015865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AH66_015910	COG1272	protein, Hemolysin III
AH66_015935	COG0745	RESPONSE REGULATOR receiver
AH66_015940	COG2205	protein histidine kinase activity
AH66_015945	COG4452	Inner membrane protein CreD
AH66_015950	COG0716	FMN binding
AH66_015955	COG4974	Belongs to the 'phage' integrase family
AH66_015960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AH66_015965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AH66_015985	COG0582	viral genome integration into host DNA
AH66_016010	COG2944	sequence-specific DNA binding
AH66_016100	COG1695	Transcriptional regulator
AH66_016105	COG0791	NLP P60 protein
AH66_016115	COG1879	ABC-type sugar transport system periplasmic component
AH66_016120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_016125	COG1129	ABC transporter
AH66_016135	COG2182	Extracellular solute-binding protein
AH66_016140	COG1175	transmembrane transport
AH66_016145	COG3833	ABC-type maltose transport systems, permease component
AH66_016150	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AH66_016155	COG1874	Beta-galactosidase
AH66_016160	COG1263	PTS System
AH66_016160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_016180	COG2271	Major facilitator Superfamily
AH66_016205	COG3119	arylsulfatase activity
AH66_016210	COG0641	radical SAM
AH66_016220	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_016230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_016235	COG3716	PTS system mannose fructose sorbose family IID component
AH66_016240	COG3715	PTS system
AH66_016245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_016250	COG2222	sugar isomerase
AH66_016260	COG1349	DNA-binding transcription factor activity
AH66_016265	COG3119	arylsulfatase activity
AH66_016305	COG0288	reversible hydration of carbon dioxide
AH66_016325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AH66_016345	COG2165	general secretion pathway protein
AH66_016385	COG0840	transmembrane signaling receptor activity
AH66_016400	COG0583	DNA-binding transcription factor activity
AH66_016405	COG2814	Major facilitator Superfamily
AH66_016410	COG0583	DNA-binding transcription factor activity
AH66_016420	COG1609	Transcriptional regulator
AH66_016450	COG0667	Aldo Keto reductase
AH66_016495	COG2226	methyltransferase
AH66_016495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AH66_016495	COG3433	isochorismatase activity
AH66_016505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AH66_016505	COG2226	methyltransferase
AH66_016505	COG3433	isochorismatase activity
AH66_016530	COG1132	(ABC) transporter
AH66_016530	COG2375	cellular response to nickel ion
AH66_016535	COG1132	(ABC) transporter
AH66_016550	COG2610	gluconate transmembrane transporter activity
AH66_016565	COG3501	Rhs element vgr protein
AH66_016575	COG3209	COG3209 Rhs family protein
AH66_016590	COG0471	metal ion transport
AH66_016640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AH66_016645	COG1191	sigma factor activity
AH66_016670	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AH66_016690	COG3710	Transcriptional regulator
AH66_016710	COG1256	bacterial-type flagellum assembly
AH66_016720	COG1706	bacterial-type flagellum-dependent cell motility
AH66_016730	COG4786	Flagellar basal body rod
AH66_016750	COG1749	Flagellar hook protein flgE
AH66_016755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AH66_016760	COG1558	bacterial-type flagellum-dependent cell motility
AH66_016765	COG1815	bacterial-type flagellum-dependent cell motility
AH66_016770	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AH66_016810	COG1677	Flagellar hook-basal body complex protein FliE
AH66_016835	COG1987	bacterial-type flagellum assembly
AH66_016840	COG1684	flagellar biosynthetic protein fliR
AH66_016845	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AH66_016865	COG4592	Periplasmic binding protein
AH66_016905	COG4964	Belongs to the GSP D family
AH66_016910	COG4964	Belongs to the GSP D family
AH66_016960	COG0848	biopolymer transport protein
AH66_016965	COG0811	peptide transport
AH66_016970	COG0626	cystathionine gamma-synthase activity
AH66_016975	COG0586	Pfam SNARE associated Golgi protein
AH66_016980	COG2207	Transcriptional regulator
AH66_016985	COG1979	alcohol dehydrogenase
AH66_016995	COG0656	L-ascorbic acid biosynthetic process
AH66_017005	COG2132	Multicopper oxidase
AH66_017015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AH66_017025	COG2249	NAD(P)H dehydrogenase (quinone) activity
AH66_017030	COG0583	DNA-binding transcription factor activity
AH66_017040	COG3150	esterase
AH66_017045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AH66_017050	COG3151	Protein conserved in bacteria
AH66_017055	COG0494	nUDIX hydrolase
AH66_017060	COG1538	Outer membrane efflux protein
AH66_017070	COG0754	glutathionylspermidine amidase activity
AH66_017075	COG3384	dioxygenase
AH66_017095	COG0531	amino acid
AH66_017110	COG3025	triphosphatase activity
AH66_017115	COG4991	sh3 domain protein
AH66_017130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AH66_017145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AH66_017150	COG0358	DNA primase activity
AH66_017220	COG0251	oxidation-reduction process
AH66_017245	COG1289	transmembrane transporter activity
AH66_017265	COG0395	ABC-type sugar transport system, permease component
AH66_017275	COG2182	Extracellular solute-binding protein
AH66_017280	COG1609	Transcriptional regulator
AH66_017285	COG3459	Glycosyltransferase 36 associated
AH66_017290	COG3842	ATPase activity
AH66_017310	COG3210	domain, Protein
AH66_017315	COG3210	domain, Protein
AH66_017345	COG3210	domain, Protein
AH66_017350	COG3210	domain, Protein
AH66_017355	COG2831	hemolysin activation secretion protein
AH66_017360	COG4245	von Willebrand factor, type A
AH66_017375	COG4245	von Willebrand factor, type A
AH66_017390	COG3247	response to pH
AH66_017395	COG0446	pyridine nucleotide-disulphide oxidoreductase
AH66_017395	COG1902	pentaerythritol trinitrate reductase activity
AH66_017410	COG1451	nucleotide metabolic process
AH66_017415	COG0673	inositol 2-dehydrogenase activity
AH66_017435	COG2721	sulfolactate sulfo-lyase activity
AH66_017450	COG2271	Major facilitator Superfamily
AH66_017465	COG0586	Pfam SNARE associated Golgi protein
AH66_017480	COG4575	ribosome binding
AH66_017485	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AH66_017495	COG2259	Doxx family
AH66_017515	COG0494	nUDIX hydrolase
AH66_017545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AH66_017550	COG0849	cell division
AH66_017555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AH66_017575	COG0772	Belongs to the SEDS family
AH66_017590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AH66_017595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AH66_017600	COG0768	penicillin binding
AH66_017605	COG3116	cell division
AH66_017630	COG1609	Transcriptional regulator
AH66_017645	COG0028	Belongs to the TPP enzyme family
AH66_017650	COG1022	Amp-dependent synthetase and ligase
AH66_017675	COG0473	3-isopropylmalate dehydrogenase activity
AH66_017690	COG2814	Major facilitator Superfamily
AH66_017715	COG4143	(ABC) transporter
AH66_017720	COG1178	ABC-type Fe3 transport system permease component
AH66_017725	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AH66_017730	COG0586	Pfam SNARE associated Golgi protein
AH66_017735	COG0417	DNA replication proofreading
AH66_017755	COG2885	chlorophyll binding
AH66_017755	COG3047	cAMP biosynthetic process
AH66_017840	COG0564	pseudouridine synthase activity
AH66_017845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AH66_017895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AH66_017905	COG2966	Psort location CytoplasmicMembrane, score
AH66_017910	COG1280	lysine exporter protein (LysE YggA)
AH66_017915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AH66_017940	COG1047	Peptidyl-prolyl cis-trans
AH66_017955	COG0196	riboflavin kinase activity
AH66_017965	COG0583	DNA-binding transcription factor activity
AH66_017985	COG1584	GPR1 FUN34 yaaH family protein
AH66_018000	COG0521	Mo-molybdopterin cofactor biosynthetic process
AH66_018040	COG0745	RESPONSE REGULATOR receiver
AH66_018045	COG3045	CreA protein
AH66_018050	COG3708	Transcriptional regulator
AH66_018050	COG2207	Transcriptional regulator
AH66_018065	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AH66_018070	COG0741	lytic transglycosylase activity
AH66_018085	COG2199	diguanylate cyclase activity
AH66_018090	COG2885	chlorophyll binding
AH66_018115	COG0560	Phosphoserine phosphatase
AH66_018120	COG3726	membrane protein affecting hemolysin expression
AH66_018145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AH66_018150	COG0084	hydrolase, TatD family'
AH66_018155	COG4667	esterase of the alpha-beta hydrolase superfamily
AH66_018165	COG2823	Periplasmic or secreted lipoprotein
AH66_018175	COG0456	acetyltransferase
AH66_018180	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AH66_018220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_018225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_018240	COG0859	PFAM glycosyl transferase family 9
AH66_018245	COG1070	Carbohydrate kinase
AH66_018295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_018295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AH66_018295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_018300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_018305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_018310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_018315	COG2207	Transcriptional regulator
AH66_018325	COG4269	membrane
AH66_018380	COG1401	restriction endodeoxyribonuclease activity
AH66_018400	COG3650	response to hydrogen peroxide
AH66_018405	COG1960	acyl-CoA dehydrogenase activity
AH66_018410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AH66_018415	COG0557	exoribonuclease II activity
AH66_018430	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AH66_018435	COG0330	HflC and HflK could
AH66_018440	COG0330	HflC and HflK could
AH66_018445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AH66_018465	COG0860	N-Acetylmuramoyl-L-alanine amidase
AH66_018470	COG0802	atpase or kinase
AH66_018475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AH66_018475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AH66_018480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AH66_018490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AH66_018505	COG3264	Mechanosensitive ion channel
AH66_018505	COG1511	domain protein
AH66_018520	COG1053	succinate dehydrogenase
AH66_018525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AH66_018535	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AH66_018600	COG3383	formate dehydrogenase (NAD+) activity
AH66_018605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_018610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_018610	COG0493	'glutamate synthase
AH66_018615	COG1309	transcriptional regulator
AH66_018675	COG1454	alcohol dehydrogenase
AH66_018685	COG0629	single-stranded DNA binding
AH66_018690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AH66_018695	COG2315	Protein conserved in bacteria
AH66_018700	COG1448	Aminotransferase
AH66_018725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AH66_018730	COG0735	belongs to the Fur family
AH66_018740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AH66_018780	COG3121	Chaperone
AH66_018840	COG1358	cellular component organization or biogenesis
AH66_018865	COG3721	Heme iron utilization protein
AH66_018870	COG0702	epimerase
AH66_018880	COG4771	TonB-dependent receptor
AH66_018885	COG3720	iron ion transport
AH66_018890	COG4558	Periplasmic binding protein
AH66_018895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_018905	COG0626	cystathionine gamma-synthase activity
AH66_018910	COG0814	amino acid
AH66_018915	COG0583	DNA-binding transcription factor activity
AH66_018920	COG0425	Belongs to the sulfur carrier protein TusA family
AH66_018925	COG2391	methyltransferase activity
AH66_019035	COG1301	dicarboxylic acid transport
AH66_019045	COG3162	membrane
AH66_019070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AH66_019085	COG0551	DNA topoisomerase type I activity
AH66_019095	COG0758	DNA mediated transformation
AH66_019125	COG3036	rescue of stalled ribosome
AH66_019130	COG0789	Transcriptional regulator
AH66_019145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AH66_019160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AH66_019165	COG0201	protein transport
AH66_019175	COG1841	ribosomal large subunit assembly
AH66_019215	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AH66_019220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AH66_019230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AH66_019235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AH66_019245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AH66_019255	COG0089	rRNA binding
AH66_019270	COG0051	transcription antitermination factor activity, RNA binding
AH66_019300	COG0049	tRNA binding
AH66_019305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AH66_019325	COG2964	Protein conserved in bacteria
AH66_019330	COG0545	Peptidyl-prolyl cis-trans isomerase
AH66_019340	COG1047	Peptidyl-prolyl cis-trans
AH66_019345	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AH66_019365	COG1216	Glycosyl transferase, family 2
AH66_019375	COG2175	clavaminate synthase activity
AH66_019380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AH66_019390	COG4521	taurine ABC transporter
AH66_019400	COG0429	hydrolase of the alpha beta-hydrolase fold
AH66_019410	COG3954	Phosphoribulokinase
AH66_019420	COG1765	OsmC-like protein
AH66_019430	COG1289	transmembrane transporter activity
AH66_019465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AH66_019470	COG1486	melibiose metabolic process
AH66_019490	COG0402	S-adenosylhomocysteine deaminase activity
AH66_019495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AH66_019515	COG0180	Tryptophanyl-tRNA synthetase
AH66_019520	COG0546	phosphoglycolate phosphatase activity
AH66_019525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AH66_019550	COG4796	Type ii and iii secretion system protein
AH66_019575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AH66_019580	COG0494	nUDIX hydrolase
AH66_019590	COG1011	Hydrolase
AH66_019595	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AH66_019620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AH66_019625	COG2183	response to ionizing radiation
AH66_019630	COG1918	ferrous iron import across plasma membrane
AH66_019665	COG1640	4-alpha-glucanotransferase
AH66_019670	COG0058	SHG alpha-glucan phosphorylase activity
AH66_019675	COG0058	SHG alpha-glucan phosphorylase activity
AH66_019685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AH66_019695	COG1349	DNA-binding transcription factor activity
AH66_019710	COG0460	homoserine dehydrogenase
AH66_019710	COG0527	aspartate kinase activity
AH66_019725	COG4682	membrane
AH66_019735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AH66_019740	COG1609	Transcriptional regulator
AH66_019745	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AH66_019760	COG1575	Belongs to the MenA family. Type 1 subfamily
AH66_019815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AH66_019825	COG1494	fructose-1,6-bisphosphatase
AH66_019835	COG3152	Membrane
AH66_019850	COG0583	DNA-binding transcription factor activity
AH66_019855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AH66_019860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AH66_019865	COG0471	metal ion transport
AH66_019875	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AH66_019900	COG3678	ATP-independent chaperone mediated protein folding
AH66_019905	COG0745	RESPONSE REGULATOR receiver
AH66_019910	COG2205	protein histidine kinase activity
AH66_019915	COG2169	Transcriptional regulator
AH66_019915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AH66_019920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AH66_019925	COG1045	serine acetyltransferase
AH66_019940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AH66_019945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AH66_019955	COG4942	peptidase
AH66_019970	COG0156	8-amino-7-oxononanoate synthase activity
AH66_019980	COG0859	PFAM glycosyl transferase family 9
AH66_019985	COG0859	PFAM glycosyl transferase family 9
AH66_019990	COG1519	Transferase
AH66_020025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AH66_020055	COG1561	YicC-like family, N-terminal region
AH66_020060	COG2860	membrane
AH66_020080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AH66_020085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AH66_020090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AH66_020100	COG0786	glutamate:sodium symporter activity
AH66_020105	COG2233	PERMEase
AH66_020110	COG2982	Protein involved in outer membrane biogenesis
AH66_020115	COG0456	acetyltransferase
AH66_020140	COG1011	Hydrolase
AH66_020150	COG0174	glutamine synthetase
AH66_020155	COG3852	Histidine kinase
AH66_020165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AH66_020185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AH66_020185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AH66_020190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AH66_020195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AH66_020200	COG3084	Protein conserved in bacteria
AH66_020210	COG1763	Mo-molybdopterin cofactor biosynthetic process
AH66_020215	COG3328	transposase activity
AH66_020240	COG2186	Transcriptional regulator
AH66_020245	COG0477	Major facilitator Superfamily
AH66_020260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_020290	COG1522	sequence-specific DNA binding
AH66_020295	COG0716	FMN binding
AH66_020310	COG3312	ion transport
AH66_020365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AH66_020370	COG0573	inorganic phosphate transmembrane transporter activity
AH66_020375	COG0581	inorganic phosphate transmembrane transporter activity
AH66_020385	COG0704	Plays a role in the regulation of phosphate uptake
AH66_020395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_020400	COG0765	amino acid transport
AH66_020405	COG0765	amino acid transport
AH66_020410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_020420	COG2252	PERMEase
AH66_020450	COG0706	membrane insertase activity
AH66_020465	COG0230	Belongs to the bacterial ribosomal protein bL34 family