locus-tag class description CH46_1 ENOG4105MPN Membrane CH46_10 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CH46_100 ENOG4107QHF type ii secretion system protein e CH46_1000 ENOG4105D13 transposase CH46_1006 ENOG4105DQ6 Transposase CH46_1008 ENOG4105MEV Acyl-transferase CH46_1009 ENOG4106EAR Fimbrial protein CH46_1012 ENOG4108TTM chaperone CH46_1014 ENOG4105CMG Carbohydrate kinase CH46_1016 ENOG4105DFW ABC transporter CH46_1018 ENOG4107RNG ABC transporter CH46_1019 ENOG4105T16 Transcriptional regulator (AraC family) CH46_102 ENOG4105D7Q type ii secretion system CH46_1021 ENOG4105DFP Integrase CH46_1023 ENOG4105ZTC transcriptional activator, Ogr delta CH46_1028 ENOG4108IPW abc transporter atp-binding protein CH46_1030 ENOG4105CM4 permease protein CH46_1036 ENOG4105C6T cysteine synthase CH46_1038 ENOG4105C84 Histidine ammonia-lyase CH46_1039 ENOG4105C85 amino acid CH46_1041 ENOG4105DIJ Phosphoethanolamine transferase CH46_1042 ENOG4108KX4 response regulator CH46_1043 ENOG4105BZU Histidine kinase CH46_1047 ENOG4105BZU Histidine kinase CH46_1048 ENOG4105CXY transporter CH46_1052 ENOG4105D5K Hemolysin activator protein CH46_1054 ENOG4105DEF Extracellular solute-binding protein, family 5 CH46_1055 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH46_1056 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH46_1057 ENOG4105C3U ABC transporter CH46_1058 ENOG4108JQ7 (ABC) transporter CH46_1059 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) CH46_1060 ENOG4105BZU Histidine kinase CH46_1061 ENOG4108PU9 oligogalacturonate-specific porin CH46_1066 ENOG4105CS0 peptidase CH46_1067 ENOG4107SS6 2-dehydro-3-deoxygluconokinase CH46_1068 ENOG4105VSH 4-oxalocrotonate tautomerase CH46_1069 ENOG4105CMB EAL domain-containing protein CH46_1070 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) CH46_1071 ENOG41066T0 asmA family CH46_1072 ENOG4107H3J ribonuclease CH46_1077 ENOG4105BZW Glycerate kinase CH46_1078 ENOG4107QQ0 gntp family CH46_1079 ENOG4107VHA regulatoR CH46_1080 ENOG4105DC8 reductase CH46_1081 ENOG4105D6S protein involved in catabolism of external DNA CH46_1082 ENOG4105DGW oligopeptidase A CH46_1086 ENOG4108M6U Universal stress protein A CH46_1088 ENOG4108RS6 transposase CH46_1089 ENOG4105CJ3 phosphate transporter CH46_1090 ENOG4105CBX hi0933 family CH46_1093 ENOG4105CNN ABC, transporter CH46_1094 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH46_1096 ENOG4105D2N Aldolase CH46_1098 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH46_1100 ENOG4105C2I pirin domain protein CH46_1101 ENOG4105DIQ Transcriptional regulator CH46_1102 ENOG4105C6Z Gluconate CH46_1103 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CH46_1107 ENOG41076UM multiple antibiotic resistance (MarC)-related protein CH46_1108 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CH46_1120 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CH46_1121 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CH46_1124 ENOG4105DQ6 Transposase CH46_1131 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase CH46_1135 ENOG4105X58 receptor CH46_1138 ENOG4107QZV Type I secretion membrane fusion protein CH46_1139 ENOG4105YHG TonB family CH46_1140 ENOG4107QN2 dihydrolipoyl dehydrogenase CH46_1141 ENOG4105EHV domain protein CH46_1143 ENOG4105C5Q Transcriptional regulator CH46_1146 ENOG4108Y73 Membrane CH46_115 ENOG4105C8Q Methyl-accepting chemotaxis CH46_1156 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator CH46_1157 ENOG4105C2J ABC transporter CH46_1158 ENOG4107R9N ABC transporter CH46_1160 ENOG41062B0 ABC transporter, permease CH46_1161 ENOG4108WFC UPF0438 protein yifE CH46_1162 ENOG4105C0P Mg chelatase subunit ChlI CH46_1164 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit CH46_1165 ENOG4105CM2 brancheD-chain amino acid aminotransferase CH46_1167 ENOG4105C7B Threonine dehydratase CH46_117 ENOG4105EJC lysr family transcriptional regulator CH46_1174 ENOG4105EMY transcriptional regulator CH46_118 ENOG4105RQF LysR family Transcriptional regulator CH46_1181 ENOG4108VEV chaperone CH46_1183 ENOG4105CW0 outer membrane usher protein CH46_1184 ENOG4105GQR Chaperone CH46_1188 ENOG4105KQ5 peptidylprolyl cis-trans isomerase CH46_1189 ENOG4105C4R Atp-dependent dna helicase CH46_119 ENOG4105F27 Major Facilitator CH46_1193 ENOG4105K63 Thioredoxin CH46_1195 ENOG4105ESV Glycosyl transferase, family 4 CH46_1196 ENOG4105SFE lipopolysaccharide biosynthesis protein CH46_1197 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CH46_1198 ENOG4108IJ1 Dehydrogenase CH46_1199 ENOG4105C1B dTDP-glucose 4-6-dehydratase CH46_120 ENOG41060NJ transcriptional regulator CH46_1200 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CH46_1201 ENOG4108WJ1 acetyltransferase CH46_1202 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CH46_1203 ENOG4105EGZ biosynthesis protein CH46_1207 ENOG4105C85 amino acid CH46_121 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CH46_1213 ENOG4108RS6 transposase CH46_1214 ENOG410601J HemY protein CH46_1215 ENOG4105ECF c-methyltransferase CH46_1216 ENOG41076E6 Uroporphyrinogen-III Synthase CH46_1218 ENOG4107T0K Adenylate cyclase CH46_1220 ENOG4105S7Z (LipO)protein CH46_1222 ENOG4105CT0 Protein of unknown function, DUF484 CH46_1223 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CH46_1224 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant CH46_1225 ENOG4105C4R Atp-dependent dna helicase CH46_1227 ENOG4105EQN UPF0261 protein CH46_1229 ENOG4107QUT magnesium and cobalt transport protein CorA CH46_1230 ENOG4105FR1 rard protein CH46_1231 ENOG4108VUY thioesterase Superfamily protein CH46_1232 ENOG4105HDD phospholipase CH46_1233 ENOG4105C9U ATP-dependent DNA helicase RecQ CH46_1234 ENOG4105CCF Lysine exporter protein (Lyse ygga) CH46_1236 ENOG4108EUD Lysophospholipase CH46_1237 ENOG4105DQF Hydrolase CH46_1239 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase CH46_1240 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A CH46_1242 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CH46_1243 ENOG4108W1V Lipoprotein CH46_1244 ENOG4105EX9 Membrane CH46_1247 ENOG4107FS9 Membrane CH46_1250 ENOG4105MG3 Membrane CH46_1251 ENOG4106H78 methyltransferase CH46_1252 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CH46_1252 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CH46_1253 ENOG4105CAK Cell division ATP-binding protein ftsE CH46_1254 ENOG4105CRP Part of the ABC transporter FtsEX involved in CH46_1256 ENOG4108RS6 transposase CH46_1257 ENOG4105U59 -acetyltransferase CH46_1258 ENOG4105CP9 extracellular ligand-binding receptor CH46_1259 ENOG4105C32 Amino acid ABC transporter (Permease) CH46_1260 ENOG4105CF8 branched-chain amino acid ABC transporter, permease CH46_1261 ENOG4105C0Z ABC transporter CH46_1262 ENOG4108IV0 ABC, transporter CH46_127 ENOG4105CPC Aldo Keto reductase CH46_1274 ENOG4107T6V glycerophosphoryl diester phosphodiesterase CH46_1275 ENOG4105RK9 auxin efflux carrier CH46_1276 ENOG4105DZ2 Transcriptional regulator CH46_1277 ENOG4105EMK carboxylate amino acid amine transporter CH46_1279 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) CH46_1280 ENOG4108I5U Uridine phosphorylase CH46_1283 ENOG4108KF1 Membrane CH46_1284 ENOG4105CGY Dna recombination protein CH46_1286 ENOG4105JC1 sterol-binding domain protein CH46_1288 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) CH46_1290 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CH46_1295 ENOG4105D52 delta-aminolevulinic acid dehydratase CH46_1296 ENOG4105MDZ Transcriptional activator rfaH CH46_1298 ENOG4107QK7 reductase CH46_130 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase CH46_1302 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CH46_1303 ENOG4108RS6 transposase CH46_1304 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CH46_1305 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CH46_1306 ENOG4108RR8 protoporphyrinogen oxidase CH46_1313 ENOG4105D4A Cell wall formation (By similarity) CH46_1314 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CH46_1324 ENOG4105PM1 preprotein translocase subunit SecE CH46_1325 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CH46_1332 ENOG4108RS6 transposase CH46_1333 ENOG4105D41 biosynthesis protein thiH CH46_1334 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) CH46_1336 ENOG4105D06 uba thif-type nad fad binding protein CH46_1338 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) CH46_1343 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) CH46_1344 ENOG4105R2J Conserved Protein CH46_1346 ENOG4108T8B Protein of unknown function (DUF1481) CH46_1347 ENOG4105C12 Phosphoribosylglycinamide synthetase CH46_1360 ENOG4107QP3 malate synthase g CH46_1361 ENOG4108I9X Isocitrate lyase CH46_1363 ENOG41069M3 Transcriptional regulator CH46_1364 ENOG41069M3 Transcriptional regulator CH46_1365 ENOG4105C3R Methionine synthase CH46_1368 ENOG4105CFH Aspartokinase CH46_1371 ENOG4105EG2 ABC transporter, permease CH46_1372 ENOG4105D56 permease protein CH46_1373 ENOG4107FKK extracellular solute-binding protein family 1 CH46_1377 ENOG4107W52 maltose operon periplasmic protein CH46_1379 ENOG4108WC9 type VI secretion system effector, hcp1 family CH46_138 ENOG4105C0W non-ribosomal peptide synthetase CH46_1383 ENOG4105DQ6 Transposase CH46_1392 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH46_1399 ENOG4105CS6 Rhs element vgr protein CH46_140 ENOG4105C0W non-ribosomal peptide synthetase CH46_1402 ENOG4105CNA YD repeat protein CH46_1408 ENOG4105CS6 Rhs element vgr protein CH46_1410 ENOG4105CNA YD repeat protein CH46_1413 ENOG4107TYG Oxidoreductase domain-containing protein CH46_1414 ENOG4105W4W Transcriptional regulator CH46_1415 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) CH46_1416 ENOG4108RVA ribokinase CH46_1417 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH46_1419 ENOG4105GVF (ABC) transporter CH46_1421 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CH46_1424 ENOG4105C7N Xanthine uracil vitamin C permease CH46_1425 ENOG4105EEQ Na H antiporter CH46_1427 ENOG4105D1S lipid A biosynthesis CH46_1429 ENOG4105C2J ABC transporter CH46_1430 ENOG4105CNN ABC, transporter CH46_1432 ENOG4105EF1 ribulokinase CH46_1433 ENOG4105C2X Arabinose 5-phosphate isomerase CH46_1434 ENOG4105CYM Glutathione S-transferase CH46_1437 ENOG4108RS6 transposase CH46_1438 ENOG4105VEQ Cold shock protein CH46_1439 ENOG4105VEQ Cold shock protein CH46_1440 ENOG4108XTF Outer Membrane Lipoprotein CH46_1443 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase CH46_1444 ENOG4105CSH Transporter CH46_1447 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) CH46_1448 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CH46_1450 ENOG4108IA2 Sodium pantothenate symporter CH46_1451 ENOG4105RG0 Membrane CH46_1453 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CH46_1454 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein CH46_1457 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) CH46_1458 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CH46_1459 ENOG41062P1 Diguanylate cyclase phosphodiesterase CH46_1460 ENOG4105DFF Rod shape-determining protein mreb CH46_1461 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CH46_1462 ENOG4105VQ7 Rod shape-determining protein MreD CH46_1464 ENOG4105C03 ribonuclease CH46_1465 ENOG4105QD6 exported protein CH46_1467 ENOG4105D1U peptidase U62 modulator of DNA gyrase CH46_147 ENOG4105BZ1 (ABC) transporter CH46_1478 ENOG4105CR8 Transcriptional regulator CH46_1482 ENOG4105C26 Dehydrogenase CH46_1485 ENOG4105UNR (Barnase) inhibitor CH46_1487 ENOG4105CMS peptidase U62, modulator of DNA gyrase CH46_1489 ENOG4108XVM Cytochrome b(562) CH46_1490 ENOG4105NXH GreA GreB family elongation factor CH46_1491 ENOG4105CG3 alpha amylase, catalytic region CH46_1492 ENOG4105C5Y PTS System CH46_1493 ENOG4105D4X repressor CH46_1501 ENOG4105KME endoribonuclease L-psp CH46_1504 ENOG41080Z8 PHOSPHOCARRIER protein CH46_1506 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN CH46_1507 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA CH46_1508 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH46_1509 ENOG4108IUZ ABC transporter CH46_151 ENOG4107EFN gluconate transport system permease 3 CH46_1510 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA CH46_1511 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) CH46_1512 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase CH46_1513 ENOG4105C2X Arabinose 5-phosphate isomerase CH46_1514 ENOG4105FEU K -dependent Na -Ca exchanger CH46_1515 ENOG4105DHJ ABC, transporter CH46_1516 ENOG4105CY3 ABC transporter, permease CH46_1517 ENOG4107PE3 Mammalian cell entry related domain protein CH46_1518 ENOG4105E3I toluene tolerance CH46_1519 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane CH46_1520 ENOG4105VFK BolA family CH46_1522 ENOG4105C0H protease CH46_1523 ENOG4108RS6 transposase CH46_1524 ENOG4105C0H protease CH46_1525 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III CH46_1526 ENOG4105D6Z AFG1 family ATPase CH46_1529 ENOG4107MKT Stringent starvation protein a CH46_1530 ENOG4105KB2 stringent starvation protein b CH46_1532 ENOG4105BZ8 glutamate synthase CH46_1533 ENOG4105CBC glutamate synthase CH46_1534 ENOG4105N5T Radical SAM Protein CH46_1535 ENOG4105BZU Histidine kinase CH46_1536 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain CH46_1538 ENOG4105W4M Transport-associated protein CH46_154 ENOG4105CS6 Rhs element vgr protein CH46_1542 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CH46_1543 ENOG4108CNN domain protein CH46_1544 ENOG4105CWB LysR family transcriptional Regulator CH46_1545 ENOG4105CHF Glutathione S-transferase CH46_1548 ENOG4108MXZ Esterase CH46_1550 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) CH46_1551 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) CH46_1553 ENOG4108RS6 transposase CH46_1555 ENOG4105FHY Opacity-associated protein A CH46_1556 ENOG4108V1T peptidylprolyl cis-trans isomerase CH46_1558 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic CH46_1559 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase CH46_156 ENOG4105CNA YD repeat protein CH46_1560 ENOG4108UUE Transcriptional regulator CH46_1561 ENOG41061GZ Protein of unknown function (DUF1107) CH46_1562 ENOG4105C37 (CBS) domain CH46_1564 ENOG4105CFU surface antigen CH46_1565 ENOG4105MA0 exported protein CH46_1566 ENOG4108ZHD aig2 family CH46_1567 ENOG4105F0N pyrophosphate phospho-hydrolase CH46_1569 ENOG4105DFU Cell wall formation (By similarity) CH46_1573 ENOG4105HVQ Regulatory factor of maltose metabolism CH46_1575 ENOG4105EAH synthase CH46_1578 ENOG4105QYV Membrane CH46_158 ENOG41062WK cellular response to acidity CH46_1582 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase CH46_1583 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) CH46_1584 ENOG4105HBR Rna-binding protein CH46_1586 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CH46_1587 ENOG4105EEI dihydropteroate synthase CH46_159 ENOG4105C8P )-transporter CH46_1593 ENOG4105CHV Transcription elongation factor NusA CH46_1599 ENOG4105DQ6 Transposase CH46_160 ENOG4105ETE Transcriptional regulator (LacI family CH46_1602 ENOG4105C1J atp-dependent rna helicase CH46_1605 ENOG4105DEN Luciferase family CH46_1608 ENOG4105BZS acriflavin resistance protein CH46_1609 ENOG4105ENJ RND efflux system, outer membrane lipoprotein CH46_161 ENOG4105DQ6 Transposase CH46_1610 ENOG4106RZ4 Peptidase U32 CH46_1611 ENOG4105CFP Peptidase U32 CH46_1612 ENOG4105XPQ lipid carrier protein CH46_1613 ENOG4108YYD acetyltransferase CH46_1618 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component CH46_1619 ENOG4105DRS transport system, permease CH46_1623 ENOG4105K4T epimerase CH46_1624 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein CH46_1625 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) CH46_1626 ENOG4105FD8 phosphonate metabolism protein PhnM CH46_1627 ENOG4105HRV phosphonate c-p lyase system protein phnl CH46_1628 ENOG4105ENV phosphonate C-P lyase system protein PhnK CH46_1629 ENOG4105FT8 Phosphonate metabolism CH46_1630 ENOG4105EKV Phosphonate metabolism protein CH46_1631 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH CH46_1632 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG CH46_1633 ENOG4107RJJ Transcriptional regulator CH46_1635 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) CH46_1636 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CH46_1637 ENOG4108JQ7 (ABC) transporter CH46_1638 ENOG4105C3U ABC transporter CH46_1639 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH46_164 ENOG4108XTF Outer Membrane Lipoprotein CH46_1640 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH46_1643 ENOG4105XEP YhcH YjgK YiaL family protein CH46_1644 ENOG4105DBV ornithine carbamoyltransferase CH46_1645 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) CH46_1646 ENOG4108MJ3 acetyltransferase CH46_1647 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) CH46_1648 ENOG4105MYG DNA polymerase iii, chi subunit CH46_165 ENOG4108XTF Outer Membrane Lipoprotein CH46_1650 ENOG4108M8S permease YjgP YjgQ family protein CH46_1651 ENOG4108K5H permease YjgP YjgQ family protein CH46_1655 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) CH46_1661 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CH46_1663 ENOG4105D7Q type ii secretion system CH46_1664 ENOG4107QHF type ii secretion system protein e CH46_1665 ENOG4108ZUW Major pilin subunit CH46_1666 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CH46_1667 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH46_1668 ENOG4106A72 regulatory protein AmpE CH46_1669 ENOG4105C85 amino acid CH46_1670 ENOG41073TP transcriptional regulator CH46_1671 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CH46_1672 ENOG4107QSN dihydrolipoamide acetyltransferase CH46_1673 ENOG4107QN2 dihydrolipoyl dehydrogenase CH46_1674 ENOG4108RS6 transposase CH46_1675 ENOG4107QIJ Aconitate hydratase 2 CH46_1677 ENOG4105RPH Inner membrane protein YddG CH46_1680 ENOG4108ZRK uncharacterized protein yacC CH46_1681 ENOG4105E3B Multicopper oxidase CH46_1682 ENOG4108UGV hypoxanthine phosphoribosyltransferase CH46_1683 ENOG41077A9 carbonic anhydrase CH46_1684 ENOG4105DA5 (ABC) transporter CH46_1685 ENOG4105E3A (ABC) transporter CH46_1686 ENOG4107BJW polysaccharide deacetylase CH46_1690 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CH46_1691 ENOG4105DJ0 Poly(A) Polymerase CH46_1692 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) CH46_1693 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters CH46_1695 ENOG4107XID 2'-5' rna ligase CH46_1696 ENOG4105CQ7 ATP-dependent helicase CH46_1697 ENOG4105BZ4 penicillin-binding protein CH46_1698 ENOG4105E0A ABC, transporter CH46_1699 ENOG4105J76 Periplasmic binding protein CH46_170 ENOG4107RD7 Flagellar Motor Protein, MotA CH46_1700 ENOG4105S6R Iron-hydroxamate transporter permease subunit CH46_1704 ENOG4105EN6 Membrane CH46_1706 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) CH46_1708 ENOG4105C0H protease CH46_1709 ENOG4105BZU Histidine kinase CH46_1710 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CH46_1711 ENOG4105DXN mazG family CH46_1715 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CH46_1716 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CH46_1731 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) CH46_1732 ENOG4105N0Z inner membrane protein ygbE CH46_1734 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) CH46_1739 ENOG4108K5P (LipO)protein CH46_1740 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH46_1741 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) CH46_1742 ENOG4108YZG isomerase CH46_1743 ENOG4105CPQ Dehydrogenase CH46_1744 ENOG4105CHR reductase CH46_1745 ENOG4105CMT Dihydroxyacetone kinase CH46_1747 ENOG4105DKT Transcriptional regulator CH46_1752 ENOG4105E89 ABC transporter CH46_1753 ENOG4105CA0 peroxidase CH46_1755 ENOG4105D05 Receptor CH46_1758 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CH46_176 ENOG410804A Flagellar hook-associated 2 domain-containing protein CH46_1760 ENOG4107GFK fumarate CH46_1761 ENOG4105CMG Carbohydrate kinase CH46_1762 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase CH46_1763 ENOG4105F5R ABC transporter CH46_1764 ENOG4105CNN ABC, transporter CH46_1765 ENOG4105C2J ABC transporter CH46_1766 ENOG4108RS6 transposase CH46_1768 ENOG4105E98 transcriptional regulator DeoR family CH46_1769 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CH46_1770 ENOG4107QY8 reductase CH46_1771 ENOG4105QAX Iron-sulfur CH46_1772 ENOG4107KGK dmso reductase anchor subunit CH46_1773 ENOG4108NEM leader-binding protein dmsD CH46_1774 ENOG4105CPW cytochrome b561 CH46_1775 ENOG4108XVM Cytochrome b(562) CH46_1779 ENOG4105C2J ABC transporter CH46_1780 ENOG4105CNN ABC, transporter CH46_1781 ENOG4108HHA Transketolase CH46_1782 ENOG4108IUS Transketolase CH46_1783 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CH46_1790 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CH46_1791 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) CH46_1796 ENOG4107VXZ Hydrolase CH46_1797 ENOG4105W39 Membrane CH46_1798 ENOG4105D9M gamma-glutamylcysteine synthetase CH46_18 ENOG4108UT2 hemolysin iii CH46_180 ENOG4108M3R transcriptional activator CadC CH46_1800 ENOG4108RS6 transposase CH46_1801 ENOG4108JU6 CBS domain protein CH46_1802 ENOG4106KVJ cytochrome C assembly protein CH46_1803 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CH46_1808 ENOG4108RS6 transposase CH46_1809 ENOG4108NE3 Salt-induced outer membrane protein CH46_1810 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH46_1811 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH46_1812 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH46_1813 ENOG4108NEV two component transcriptional regulator, LytTR family CH46_1814 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH46_1815 ENOG4105EHE chorismate mutase- prephenate dehydrogenase CH46_1821 ENOG4108RS6 transposase CH46_1822 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA CH46_1823 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane CH46_1824 ENOG4105C34 Pseudouridine synthase CH46_1825 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CH46_1826 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH46_1833 ENOG4105T42 (LipO)protein CH46_1834 ENOG4105JIM Phosphatidylserine synthase CH46_1835 ENOG4105CD5 CoA-binding domain protein CH46_1836 ENOG4106IUH DTW domain containing protein CH46_1837 ENOG4105K63 Thioredoxin CH46_1838 ENOG4105EIB trna rrna methyltransferase CH46_1839 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH46_184 ENOG4105E1Q flagellar hook-associated protein CH46_1840 ENOG4105CW7 secretion protein, HlyD family CH46_1841 ENOG4105NTK Transcriptional repressor Mpra CH46_1842 ENOG4105ZED uncharacterized protein ygaH CH46_1843 ENOG4108UMN azlc family CH46_1844 ENOG4105EQ0 Major Facilitator superfamily CH46_1851 ENOG4105E5Q amino acid AbC transporter CH46_1853 ENOG4105C5R Aminotransferase CH46_1857 ENOG4105C5R Aminotransferase CH46_186 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CH46_1861 ENOG4106YJS accessory processing protein CH46_1863 ENOG4107QPN acyl-Coa dehydrogenase CH46_1865 ENOG4105F7V ErfK ybiS ycfS ynhG family protein CH46_1866 ENOG4105E7A Glutamine amidotransferase CH46_1867 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH46_1868 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH46_1869 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH46_187 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CH46_1873 ENOG4105CJ2 (LipO)protein CH46_1877 ENOG4105CIN aminoacyl-histidine dipeptidase CH46_188 ENOG4105CGA flagellar basal-body rod protein FlgG CH46_1888 ENOG4105F2W methyltransferase CH46_189 ENOG4108KPB Flagellar basal-body rod protein FlgF CH46_1893 ENOG4105DKQ ROK family CH46_1896 ENOG4105EYH Exonuclease CH46_1897 ENOG4107RH8 nuclease SbcCD subunit D CH46_1898 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CH46_1899 ENOG4105BZU Histidine kinase CH46_190 ENOG4108RS6 transposase CH46_1901 ENOG4105CWM branched-chain amino acid transport system II carrier protein CH46_1902 ENOG4105C85 amino acid CH46_1903 ENOG4107R28 alpha amylase, catalytic region CH46_1904 ENOG4105CHR reductase CH46_1907 ENOG4108RS6 transposase CH46_1908 ENOG4105D3R alkyl hydroperoxide reductase CH46_1909 ENOG4108ZYK Acyl carrier protein phosphodiesterase CH46_1910 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) CH46_1912 ENOG4105VIE preprotein translocase, subunit YajC CH46_1913 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CH46_1914 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CH46_1918 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CH46_192 ENOG4105BZE flagellar hook protein, FlgE CH46_1921 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CH46_1922 ENOG4108ZAI phosphatidylglycerophosphatase a CH46_1923 ENOG4108RS6 transposase CH46_1925 ENOG4105CTB Polyprenyl synthetase CH46_1928 ENOG4107S0N DJ-1 family CH46_1929 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CH46_193 ENOG4105W00 Flagellar hook capping protein CH46_1931 ENOG4107RDB Major Facilitator CH46_1933 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) CH46_1934 ENOG4105CCU oxidase (Subunit III) CH46_1935 ENOG4105BZ9 Cytochrome C oxidase, subunit I CH46_1936 ENOG4105E2S oxidase) subunit II CH46_1937 ENOG4108NFH Sugar hydrolase CH46_1938 ENOG4105EYM Major Facilitator superfamily CH46_1939 ENOG4105IEY (LipO)protein CH46_194 ENOG4108ZC9 flagellar basal-body rod protein flgc CH46_1940 ENOG4105M85 Bola protein CH46_1945 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) CH46_1946 ENOG4105K70 DNA-binding protein CH46_1947 ENOG4105EIN peptidylprolyl cis-trans isomerase CH46_1948 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein CH46_1949 ENOG4108TGP Thioesterase superfamily protein CH46_195 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CH46_1951 ENOG4108NFA extracellular solute-binding protein CH46_1953 ENOG4105C6T cysteine synthase CH46_1954 ENOG4108XM1 transcriptional regulator AsnC family CH46_1955 ENOG4105BZ1 (ABC) transporter CH46_1956 ENOG4105BZ1 (ABC) transporter CH46_1957 ENOG4108YZA Nitrogen regulatory protein pii CH46_1958 ENOG4105BZU Histidine kinase CH46_1959 ENOG4105C29 acyl-CoA thioesterase CH46_196 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA CH46_1960 ENOG4108MNP Glycoprotein polysaccharide metabolism CH46_1961 ENOG41080UX Methyltransferase CH46_1962 ENOG4105KF5 hemolysin expression-modulating protein CH46_1963 ENOG4108UKR Biofilm formation regulator YbaJ CH46_1965 ENOG4105YK5 50S ribosomal protein L36 CH46_1967 ENOG4105BZS acriflavin resistance protein CH46_1968 ENOG4105C1P efflux transporter, rnd family, mfp subunit CH46_1969 ENOG4108IG5 Transcriptional regulator CH46_1970 ENOG41090EX DsrE family CH46_1971 ENOG4105EGS Mechanosensitive ion channel CH46_1973 ENOG4105WD1 Membrane CH46_1977 ENOG4107QMP dna polymerase iii subunits gamma and tau CH46_1983 ENOG4108EX3 reductase CH46_1984 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase CH46_1985 ENOG4105FAW cDP-glucose 4,6-dehydratase CH46_1986 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CH46_1987 ENOG4108SMP Nad-dependent epimerase dehydratase CH46_1995 ENOG4108TJN glycosyl transferase group 1 CH46_1996 ENOG4105C0K Gdp-mannose 4,6-dehydratase CH46_1997 ENOG4105C0K Gdp-mannose 4,6-dehydratase CH46_200 ENOG4108JIR Flagellum-specific ATP synthase CH46_2000 ENOG4105CJT Mannose-1-phosphate guanylyltransferase CH46_2003 ENOG4108QY5 Ferric enterobactin transport protein CH46_2004 ENOG4107RE1 Inosine-guanosine kinase CH46_2005 ENOG4105CKD glutathione-regulated potassium-efflux system protein CH46_2006 ENOG4105EU0 Major facilitator Superfamily CH46_2007 ENOG4105CGH 5'-nucleotidase CH46_2008 ENOG4105CGH 5'-nucleotidase CH46_2009 ENOG4105CGH 5'-nucleotidase CH46_2012 ENOG4108Z66 YbaK ebsC protein CH46_2013 ENOG4105MBR gumn family CH46_2014 ENOG4105C59 p-type ATPase CH46_2015 ENOG4108Z6Z Transcriptional regulator CH46_2016 ENOG4105G5H Membrane CH46_2017 ENOG4107QX8 SPFH domain, Band 7 family protein CH46_2018 ENOG4107QR8 Thioredoxin CH46_2019 ENOG4105E1F short-chain dehydrogenase reductase CH46_2020 ENOG4108UJV acyl-CoA thioesterase i CH46_2021 ENOG4108I0Y (ABC) transporter CH46_2022 ENOG4105CV6 ABC transporter, permease CH46_2023 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CH46_2024 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CH46_2026 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CH46_2029 ENOG4108RS6 transposase CH46_203 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CH46_2031 ENOG4105K89 arsenate reductase CH46_2032 ENOG4105ERG peptidase m48, ste24p CH46_2033 ENOG4105C02 permease CH46_2036 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CH46_2037 ENOG4105RH4 Glycine cleavage system transcriptional repressor CH46_2039 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH46_2040 ENOG4108RS6 transposase CH46_2042 ENOG4105CGZ zinc metallopeptidase CH46_2048 ENOG4105KUZ arsenate reductase CH46_205 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH46_2050 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC CH46_2051 ENOG4107Z33 ABC transporter, permease CH46_2052 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH46_2053 ENOG4105ENH Sulfatase CH46_2054 ENOG4105C4X radical SAM domain protein CH46_2055 ENOG4105S2T inner membrane protein YbcI CH46_2057 ENOG4105BZS acriflavin resistance protein CH46_2059 ENOG4105WH1 Two component transcriptional regulator luxr family CH46_2060 ENOG4108ZNS ferredoxin-type protein NapF CH46_2061 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase CH46_2063 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) CH46_2064 ENOG4105CUW cytochrome C-TYPE protein CH46_2066 ENOG4105C6K Malic enzyme CH46_207 ENOG4105DD5 Flagellar motor switch protein CH46_2073 ENOG4105H4F exported protein CH46_2074 ENOG4105E7K (LipO)protein CH46_2075 ENOG4105EZR dyp-type peroxidase family protein CH46_208 ENOG4105CN7 Flagellar biosynthetic protein FliP CH46_2080 ENOG4108R66 Conserved Protein CH46_2081 ENOG4105QEK Transcriptional regulator CH46_2083 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein CH46_2084 ENOG4108I5D sulfate abc transporter CH46_2085 ENOG4105ECW sulfate abc transporter CH46_2086 ENOG4108IJ6 ABC transporter CH46_2087 ENOG4105C6T cysteine synthase CH46_2089 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH46_209 ENOG4105VS8 Flagellar biosynthetic protein fliq CH46_2090 ENOG41062D9 Histidine kinase CH46_2092 ENOG4105C87 Aminotransferase class I and II CH46_2094 ENOG4107RAQ aminopeptidase CH46_2096 ENOG4105E1V na solute symporter CH46_2099 ENOG4105DJY efflux transporter, rnd family, mfp subunit CH46_21 ENOG4105Y75 tpr repeat protein CH46_210 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CH46_2102 ENOG4105E0F Histidine kinase CH46_2106 ENOG4108RS6 transposase CH46_2107 ENOG4105C5Y PTS System CH46_2109 ENOG4105KZ7 phosphocarrier protein hpr CH46_211 ENOG4105D00 flagellar biosynthetic protein flhB CH46_2110 ENOG4105C6T cysteine synthase CH46_2111 ENOG4105EXN Sulfate transport protein CysZ CH46_2114 ENOG4105VRT cytoplasmic protein CH46_2119 ENOG4108RS6 transposase CH46_2124 ENOG4105D9N nucleoside CH46_2127 ENOG4105CPC Aldo Keto reductase CH46_2128 ENOG4105C5Q Transcriptional regulator CH46_2131 ENOG41072TH Protein of unknown function (DUF1479) CH46_2132 ENOG4105CHM Aminotransferase CH46_2133 ENOG4108VKM cytochrome b561 CH46_2135 ENOG4106B0W Curli production assembly transport component CsgG CH46_2137 ENOG4107Y60 (LipO)protein CH46_2139 ENOG4108NEM leader-binding protein dmsD CH46_2140 ENOG4107KGK dmso reductase anchor subunit CH46_2141 ENOG4105QAX Iron-sulfur CH46_2142 ENOG4107QY8 reductase CH46_2144 ENOG4108WC9 type VI secretion system effector, hcp1 family CH46_2149 ENOG4105CVE Lytic murein transglycosylase CH46_2159 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH46_216 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein CH46_2161 ENOG4105GQR Chaperone CH46_2162 ENOG4105CW0 outer membrane usher protein CH46_2164 ENOG4105CW0 outer membrane usher protein CH46_2174 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) CH46_2176 ENOG4108RS6 transposase CH46_2177 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding CH46_2178 ENOG4106G6Q Transcriptional regulator CH46_218 ENOG4106P2F Pfam:Pili_assembly_C CH46_2180 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB CH46_2181 ENOG4108Z6B deaminase CH46_2187 ENOG4108RS6 transposase CH46_2188 ENOG4107WP9 Histidine kinase CH46_2189 ENOG4108SKK alpha helix protein CH46_219 ENOG4106PG1 outer membrane usher protein CH46_2190 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH46_2191 ENOG4105C4K Nad synthetase CH46_2192 ENOG4108YZA Nitrogen regulatory protein pii CH46_2195 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CH46_2198 ENOG4108MN2 Stationary phase inducible protein CsiE CH46_2199 ENOG4105D8G Major Facilitator superfamily CH46_22 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH46_220 ENOG4108RS6 transposase CH46_2200 ENOG41065CD Exported protein CH46_2201 ENOG4105D7X high-affinity nickel-transporter CH46_2202 ENOG4108RS6 transposase CH46_2206 ENOG4105C3J Cysteine desulfurase CH46_2207 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins CH46_221 ENOG4108RS6 transposase CH46_2210 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB CH46_2211 ENOG4108ZIT Ferredoxin, 2FE-2S CH46_2212 ENOG4105WVQ Fe-S assembly protein IscX CH46_2214 ENOG4105YYA enhanced serine sensitivity protein SseB CH46_2216 ENOG4108MGN ATP-binding component of a transport system CH46_2217 ENOG4108MGN ATP-binding component of a transport system CH46_2225 ENOG4105N21 Membrane CH46_2226 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH46_2229 ENOG4105VPD cellular component movement CH46_2231 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CH46_2233 ENOG4108RS6 transposase CH46_2234 ENOG4108WC9 type VI secretion system effector, hcp1 family CH46_2240 ENOG4105D5G Transposase CH46_2244 ENOG4105DWF phosphomethylpyrimidine kinase CH46_2247 ENOG4108ZGU inhibitor of vertebrate lysozyme CH46_2249 ENOG4105CFP Peptidase U32 CH46_2250 ENOG4105KWI UPF0339 protein CH46_2251 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH46_2252 ENOG4105EB3 Histidine kinase CH46_2257 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH46_2259 ENOG4108JPW Aminotransferase CH46_2261 ENOG4105F38 ABC transporter, permease CH46_2262 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component CH46_2263 ENOG4105R8A Heat shock protein CH46_2264 ENOG4105CJW magnesium transporter CH46_2265 ENOG4105C9X ppx gppa phosphatase CH46_2266 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CH46_2267 ENOG4105C8U phosphate abc transporter CH46_2268 ENOG4105E2Z phosphate ABC transporter (Permease CH46_2270 ENOG4108C80 FliB family CH46_2271 ENOG4108C80 FliB family CH46_2272 ENOG4108MK9 spermidine N(1)-acetyltransferase CH46_2273 ENOG4108V3E phosphoribosylglycinamide formyltransferase CH46_2276 ENOG4108RS6 transposase CH46_2277 ENOG4105WQ3 Rna-binding protein CH46_2285 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase CH46_2286 ENOG4108HPI phosphatidate Cytidylyltransferase CH46_2288 ENOG4105E8V Alpha Beta Hydrolase Fold protein CH46_2289 ENOG41077RS Phosphatase CH46_2297 ENOG4105EQ2 LysR family Transcriptional regulator CH46_2298 ENOG4107SET aldo keto reductase CH46_23 ENOG4105EB3 Histidine kinase CH46_2301 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CH46_2305 ENOG4105D5G Transposase CH46_2306 ENOG4105EZE Cupin 4 family protein CH46_2311 ENOG4108WC9 type VI secretion system effector, hcp1 family CH46_2315 ENOG4105HVQ Regulatory factor of maltose metabolism CH46_2316 ENOG4108JQB penicillin-binding protein 1C CH46_2319 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CH46_2320 ENOG4105PTV Nudix Hydrolase CH46_2321 ENOG4108RE9 Phosphodiesterase CH46_2323 ENOG4105ECP epimerase CH46_2324 ENOG4108JEH abc transporter atp-binding protein CH46_2325 ENOG4106YG3 ABC transporter CH46_2326 ENOG4105DSP amino acid AbC transporter CH46_2327 ENOG4105E89 ABC transporter CH46_2328 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CH46_2329 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase CH46_2330 ENOG4105E96 Colicin v production protein CH46_2331 ENOG4108S3P Sporulation domain protein CH46_2332 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CH46_2334 ENOG4105DQR SNARE associated Golgi CH46_2336 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CH46_2337 ENOG4108RS6 transposase CH46_2340 ENOG410631K Membrane CH46_2341 ENOG4106WZ1 flagella biosynthesis regulator CH46_2344 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH46_2346 ENOG4105MH2 YfcL protein CH46_2347 ENOG4108BPE -transporting atpase CH46_2348 ENOG4105EJ9 Membrane CH46_2349 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) CH46_235 ENOG4108ZZF transport protein (ExbD) CH46_2351 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) CH46_2353 ENOG4108BY2 phosphohistidine phosphatase CH46_2356 ENOG4105KZW UPF0381 protein CH46_2357 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation CH46_2358 ENOG410903C (LipO)protein CH46_2359 ENOG4105KWW Biogenesis protein CH46_2360 ENOG4105KWW Biogenesis protein CH46_2361 ENOG4107QX9 Thiol disulfide interChange protein CH46_2362 ENOG4105DA4 cytochrome c-type biogenesis protein CH46_2364 ENOG4105X3C heme exporter protein CH46_2365 ENOG41060IM Heme exporter protein CH46_2366 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CH46_237 ENOG4105CWK Biopolymer transport protein, ExbB CH46_2370 ENOG4108V0P LemA family CH46_2372 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CH46_2378 ENOG4105CS6 Rhs element vgr protein CH46_238 ENOG4105C28 cystathionine CH46_2387 ENOG4105C3F Signal peptidase i CH46_239 ENOG4108K81 inner membrane protein YghB CH46_2390 ENOG4105WMJ Positive regulator of sigma E, RseC MucC CH46_2391 ENOG4105VQK sigma E regulatory protein, MucB RseB CH46_2392 ENOG41069PW sigma-e factor negative regulatory protein CH46_2394 ENOG4108IYU L-aspartate oxidase CH46_2396 ENOG4105C1J atp-dependent rna helicase CH46_24 ENOG4105CT7 inner membrane cred family protein CH46_240 ENOG4105CF7 AraC family transcriptional regulator CH46_2407 ENOG4107R7A Allophanate hydrolase subunit 2 CH46_2408 ENOG4105P4J Allophanate hydrolase, subunit 1 CH46_241 ENOG4108I6A alcohol dehydrogenase CH46_2410 ENOG4107QNR UPF0135 protein CH46_2411 ENOG4107RF4 Phosphodiesterase CH46_2412 ENOG4105CVP deoxyribo-dipyrimidine photolyase CH46_2413 ENOG4107SEY Conserved Protein CH46_2414 ENOG4105XIQ Protein of unknown function (DUF2517) CH46_2418 ENOG4105C08 Histidine kinase CH46_2419 ENOG4105EEX Two component transcriptional regulator (Winged helix family CH46_242 ENOG4105CV8 reductase CH46_2423 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CH46_2428 ENOG4105EZV Transcriptional regulator CH46_2429 ENOG4105VCP PTS System CH46_2430 ENOG4105CK1 PTS System CH46_2431 ENOG4105VZJ PTS System CH46_2432 ENOG41085Q9 Protein CrcB homolog CH46_2433 ENOG41086WQ Protein CrcB homolog CH46_2434 ENOG4107SVH Potassium channel protein CH46_2435 ENOG4105XXV Acid-resistance protein CH46_2439 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) CH46_2446 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CH46_2447 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) CH46_2448 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH46_2449 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH46_245 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CH46_2450 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein CH46_2451 ENOG4105VEQ Cold shock protein CH46_2456 ENOG4108SAJ Protein of unknown function (DUF1198) CH46_2457 ENOG4108WMJ Protein of unknown function (DUF2002) CH46_246 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase CH46_2462 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH46_2463 ENOG4108IJ7 Glycine betaine CH46_2464 ENOG4108HQS Glycine betaine CH46_2465 ENOG4105GIJ Glycine betaine CH46_247 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH46_2470 ENOG4105DFP Integrase CH46_2473 ENOG4105EV9 Alpha Beta Hydrolase CH46_2475 ENOG4105NNH LexA regulated protein CH46_2476 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) CH46_2477 ENOG41090R7 Ferric uptake CH46_248 ENOG4105NF4 modulator of drug activity CH46_2482 ENOG4108RS6 transposase CH46_2483 ENOG4105CI1 PTS System CH46_2485 ENOG4105CE4 GlcNAc 6-P deacetylase CH46_2486 ENOG4105E2R ROK family CH46_2487 ENOG4105D4U had-superfamily hydrolase, subfamily iia CH46_2488 ENOG4105CAQ asparagine synthetase CH46_249 ENOG4105CR8 Transcriptional regulator CH46_2494 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CH46_2496 ENOG4105C9A Phoh family CH46_2498 ENOG4108JU5 Magnesium and cobalt efflux protein CH46_2499 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) CH46_25 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) CH46_250 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH46_2500 ENOG4107RP9 extracellular solute-binding protein, family 3 CH46_2501 ENOG4105EAD ABC transporter CH46_2502 ENOG4105DRP amino acid AbC transporter CH46_2503 ENOG4105CDA abc transporter atp-binding protein CH46_2504 ENOG4107PAI alpha helical protein CH46_2507 ENOG4105DJF DNA polymerase III, delta' subunit CH46_2509 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) CH46_251 ENOG4105IPS esterase CH46_2511 ENOG4105CJN penicillin-binding protein CH46_2512 ENOG4105CNI cell division protein FtsW CH46_2513 ENOG4105K6T rare lipoprotein A CH46_2514 ENOG4105DZ1 carboxypeptidase CH46_2518 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) CH46_2519 ENOG4107Z6W Protein CrcB homolog CH46_252 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) CH46_2520 ENOG4105VEQ Cold shock protein CH46_2522 ENOG4108N8T regulatoR CH46_2527 ENOG4108JJ7 ABC transporter CH46_2529 ENOG4105DH8 myo-inositol catabolism CH46_253 ENOG4108SX3 cytoplasmic protein CH46_2531 ENOG4105EDK PfkB domain protein CH46_2532 ENOG4105CK5 oxidoreductase CH46_2533 ENOG4105CNN ABC, transporter CH46_2534 ENOG4105C2J ABC transporter CH46_2535 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH46_2536 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) CH46_2538 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) CH46_2539 ENOG4105C26 Dehydrogenase CH46_254 ENOG41087AY ADP-Ribose pyrophosphatase CH46_2544 ENOG4105DN3 alpha-2-macroglobulin domain protein CH46_2545 ENOG4108JQB penicillin-binding protein 1C CH46_2549 ENOG4107P2S Transcriptional regulator CH46_255 ENOG4105DFG type I secretion outer membrane protein CH46_2550 ENOG4105C6K Malic enzyme CH46_2554 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 CH46_2555 ENOG4107QWE )-transporter CH46_2557 ENOG4105CHM Aminotransferase CH46_2558 ENOG4107NQ8 LysR family Transcriptional regulator CH46_2560 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CH46_2562 ENOG4105GKE subunit e CH46_2563 ENOG4107QIZ NADH dehydrogenase CH46_2564 ENOG4108IEH NADH dehydrogenase subunit g CH46_2567 ENOG4107UFS subunit j CH46_2569 ENOG4105D65 subunit l CH46_2570 ENOG4105C8S subunit m CH46_2573 ENOG4108R66 Conserved Protein CH46_2574 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CH46_2575 ENOG4105CHR reductase CH46_2576 ENOG4105F32 YngK protein CH46_2577 ENOG4105K2J Transcriptional regulator CH46_2578 ENOG4105C5I Dehydrogenase CH46_258 ENOG4106032 Glutathionylspermidine synthase CH46_2581 ENOG4105C01 Dihydroxy-acid dehydratase CH46_2583 ENOG4105TNS Conserved Protein CH46_2585 ENOG4105E4F Isochorismate synthase CH46_2588 ENOG4108IPT Naphthoate synthase CH46_259 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CH46_2590 ENOG4105CEY Amp-dependent synthetase and ligase CH46_2591 ENOG4108MTB glycosyl transferase family CH46_2592 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction CH46_2598 ENOG4107SDU Methyl-accepting chemotaxis CH46_2599 ENOG4105CDA abc transporter atp-binding protein CH46_26 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CH46_2600 ENOG4105E5Q amino acid AbC transporter CH46_2601 ENOG4107R0W ABC transporter CH46_2607 ENOG4108T1M outer membrane protein x CH46_2611 ENOG4105CPQ Dehydrogenase CH46_2612 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH46_2613 ENOG4105C2J ABC transporter CH46_2614 ENOG4105CNN ABC, transporter CH46_2615 ENOG4105FKQ transcriptional regulator CH46_2616 ENOG4105EJC lysr family transcriptional regulator CH46_2617 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CH46_2618 ENOG4105C94 Transporter CH46_2619 ENOG4105DVW rieske (2Fe-2S) CH46_262 ENOG4105W0Z cytoplasmic protein CH46_2620 ENOG4105E3J oxidoreductase CH46_2621 ENOG4105D5K Hemolysin activator protein CH46_2622 ENOG4105CKT filamentous hemagglutinin CH46_2625 ENOG4105CKT filamentous hemagglutinin CH46_2628 ENOG4105CKT filamentous hemagglutinin CH46_263 ENOG4105DVH amino acid CH46_2630 ENOG4108IJ9 (ABC) transporter CH46_2632 ENOG4105ETE Transcriptional regulator (LacI family CH46_2635 ENOG4105DRS transport system, permease CH46_2636 ENOG4105HY2 Glycosidase related protein CH46_2640 ENOG4105CUY Mechanosensitive ion channel CH46_2641 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CH46_2642 ENOG4107IIZ CRISPR-associated helicase, Cas3 CH46_2643 ENOG4105ENG CRISPR-associated protein, Csy1 family CH46_2644 ENOG4105DZX CRISPR-associated protein, Csy2 family CH46_2645 ENOG4105M6W Crispr-associated protein, Csy3 family CH46_2646 ENOG4108Y1S CRISPR-associated protein, Csy4 family CH46_2647 ENOG4105CPC Aldo Keto reductase CH46_2649 ENOG4105C54 Major Facilitator superfamily CH46_2651 ENOG4105ETT transcriptional Regulator, LysR family CH46_2652 ENOG4107YC3 synthase CH46_2653 ENOG4105VJY transcriptional regulator CH46_2657 ENOG4105DSF transport protein CH46_266 ENOG4105I7R Adenylate cyclase CH46_2661 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 CH46_2662 ENOG4107PN8 YfeABCD locus regulator CH46_2663 ENOG4105FGM Fructosamine kinase CH46_2664 ENOG4105CC5 ABC transporter CH46_2665 ENOG4105CC5 ABC transporter CH46_2666 ENOG4105DIK (ABC) transporter CH46_2667 ENOG4105DSE periplasmic solute binding protein CH46_267 ENOG4106MWK domain protein CH46_2671 ENOG41087WU CH46_2676 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) CH46_2677 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) CH46_2678 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CH46_2681 ENOG4108V06 Glutathione peroxidase CH46_2682 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) CH46_2690 ENOG4108QBX (LipO)protein CH46_2694 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH46_2696 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CH46_2697 ENOG4105IPI Membrane CH46_2698 ENOG4105CQB FAD linked oxidase domain protein CH46_2699 ENOG4105KA0 thioesterase Superfamily protein CH46_27 ENOG4105T95 Thiol disulfide interChange protein CH46_270 ENOG4107ZVW dihydroneopterin aldolase CH46_2700 ENOG4108Z4V iron-sulfur cluster assembly CH46_2701 ENOG4105DIW FeS assembly protein SUFB CH46_2702 ENOG4105C3K feS assembly ATPase SufC CH46_2703 ENOG4105JRK feS assembly protein SufD CH46_2706 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CH46_2708 ENOG4108RS6 transposase CH46_2709 ENOG4105KMX major outer membrane lipoprotein CH46_2710 ENOG4105CA9 Pyruvate kinase CH46_2714 ENOG4108R6K riboflavin synthase, subunit alpha CH46_2717 ENOG4105CZQ inner membrane transport protein YdhC CH46_2718 ENOG4105F52 Transcriptional regulator CH46_2721 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CH46_2722 ENOG4105K4H Nlp p60 protein CH46_2724 ENOG4105M2J Glutaredoxin CH46_2725 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) CH46_2726 ENOG4108UYE Lactoylglutathione lyase CH46_2728 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CH46_2729 ENOG4108WUH Transcriptional regulator, TetR family CH46_273 ENOG4105VCC 30S ribosomal protein S21 CH46_2730 ENOG4105DIJ Phosphoethanolamine transferase CH46_2731 ENOG4105XZD Fe-S protein CH46_2732 ENOG4107RGM aldo keto reductase CH46_2734 ENOG4108XTF Outer Membrane Lipoprotein CH46_2736 ENOG410642K Lysozyme inhibitor CH46_274 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CH46_2740 ENOG4108K3A Glutathione S-transferase CH46_2742 ENOG4108ZR5 Conserved Protein CH46_2743 ENOG41069YE inner membrane protein yohC CH46_2744 ENOG4105DUX Transporter CH46_2746 ENOG4105Q4T oxidoreductase CH46_2747 ENOG4108JQ2 peptide transport system atp-binding protein CH46_2748 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein CH46_2749 ENOG4108EU3 peptide transport system, permease CH46_275 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH46_2750 ENOG4108I5W peptide transport system, permease protein CH46_2751 ENOG4108HIY periplasmic CH46_2752 ENOG4108RS6 transposase CH46_2753 ENOG4105E51 psp operon transcriptional activator CH46_2754 ENOG41087YS Phage shock protein A CH46_2755 ENOG4105YYT phage shock protein B CH46_2756 ENOG4105FM1 phage shock protein C CH46_2758 ENOG4105CM6 amino acid regulated cytosolic protein CH46_2763 ENOG4108RS6 transposase CH46_2764 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CH46_2765 ENOG4107S8C mandelate racemase muconate lactonizing CH46_2766 ENOG4105KXI murein peptide amidase A CH46_2767 ENOG4107QSI ABC, transporter CH46_2773 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) CH46_2775 ENOG4105KT7 mgtC SapB transporter CH46_2777 ENOG41090X5 Heat shock protein hslJ CH46_2778 ENOG4105C5I Dehydrogenase CH46_2779 ENOG4107H52 Dicarboxylate transport CH46_2780 ENOG410689M (LipO)protein CH46_2781 ENOG4105WXT Conserved Protein CH46_2782 ENOG4105DEI Mannitol dehydrogenase CH46_2783 ENOG4105DKT Transcriptional regulator CH46_2785 ENOG4105CQ7 ATP-dependent helicase CH46_2788 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap CH46_2790 ENOG4105DS1 cytochrome b561 CH46_2794 ENOG4108RS6 transposase CH46_2795 ENOG4105CTD carboxy-peptidase CH46_2796 ENOG4105JJR Histidine kinase CH46_2797 ENOG4107EXC regulatoR CH46_2799 ENOG4105D5Q Arginine ornithine antiporter CH46_28 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CH46_2800 ENOG4105C5D exported protein CH46_2801 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CH46_2802 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CH46_2803 ENOG4105Q9Y Universal stress protein CH46_2804 ENOG4105DS0 Transcriptional regulator, Crp Fnr family CH46_2805 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CH46_2809 ENOG4105PAD Hydrolase CH46_2810 ENOG4105M71 acetolactate synthase 1 regulatory subunit CH46_2811 ENOG4105C7K acetolactate synthase CH46_2816 ENOG4105FYV Amp nucleosidase CH46_2817 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CH46_2818 ENOG4107UWC ABC, transporter CH46_2819 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH46_2821 ENOG41060NJ transcriptional regulator CH46_2825 ENOG4105MQ5 zona occludens toxin CH46_2833 ENOG4105MQ5 zona occludens toxin CH46_2843 ENOG4105CMQ Chloride channel CH46_2844 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CH46_2846 ENOG4105DAG ROK family CH46_2847 ENOG4106NZI LysR family Transcriptional regulator CH46_2848 ENOG4105D94 Major Facilitator Superfamily CH46_2849 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) CH46_2850 ENOG4105C9Q fumarate hydratase class II CH46_2851 ENOG4105EIP mannose-6-phosphate isomerase CH46_2852 ENOG4106J39 exported protein CH46_2854 ENOG4105DHU Bile acid CH46_2855 ENOG4105D9R oxidoreductase CH46_2857 ENOG4105CNN ABC, transporter CH46_2859 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator CH46_2863 ENOG4108JJA ABC, transporter CH46_2864 ENOG4105C42 Type I secretion membrane fusion protein (HlyD CH46_2866 ENOG4108JJA ABC, transporter CH46_2867 ENOG4105M9B inner membrane protein ydgK CH46_2871 ENOG4105UEI Transcriptional Regulator AraC Family CH46_2872 ENOG4105D6A Electron transport complex CH46_2873 ENOG4108UQQ Electron transport complex CH46_2875 ENOG4105CSM endonuclease III CH46_2876 ENOG4105EXW epimerase dehydratase CH46_2877 ENOG4105CSP Major Facilitator Superfamily CH46_2879 ENOG4105D22 carbon starvation protein CH46_2880 ENOG4105VCD cytoplasmic protein CH46_2881 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CH46_2883 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CH46_2884 ENOG41061RM osmotically inducible lipoprotein CH46_2885 ENOG4108ZJT translation initiation factor, Sui1 CH46_2888 ENOG4105CFV Tetratricopeptide repeat protein CH46_2889 ENOG4105Q4A inner membrane protein yciS CH46_2890 ENOG4105EYK Phosphatidylglycerophosphatase B CH46_2891 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) CH46_2892 ENOG4107QM5 aconitate hydratase CH46_2894 ENOG4107R11 Transcriptional regulator CH46_2895 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CH46_2896 ENOG4105RKX Protein of unknown function (DUF2498) CH46_2897 ENOG4105ERU peptidase CH46_2898 ENOG4105UBK short-chain dehydrogenase reductase CH46_2899 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CH46_2900 ENOG4105FE9 pseudouridine synthase CH46_2901 ENOG4107RTD sua5 ycio yrdc ywlc family protein CH46_2902 ENOG4105DB7 PHP domain protein CH46_2904 ENOG4105DDQ anthranilate synthase CH46_2906 ENOG4105DK0 Indole-3-glycerol phosphate synthase CH46_2910 ENOG4105EIF outer membrane protein W CH46_2915 ENOG4105NAU thioesterase Superfamily protein CH46_2917 ENOG4105D5G Transposase CH46_2918 ENOG410822N TonB family CH46_2919 ENOG4105K9H YciI-like protein CH46_292 ENOG4105KME endoribonuclease L-psp CH46_2922 ENOG4108T1M outer membrane protein x CH46_2926 ENOG4108JQ7 (ABC) transporter CH46_2927 ENOG4105C3U ABC transporter CH46_2928 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH46_2930 ENOG4107QSI ABC, transporter CH46_2931 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein CH46_2932 ENOG4108EKI Dehydrogenase CH46_2935 ENOG4107104 thymidine kinase CH46_2937 ENOG4105C6Y Udp-glucose 6-dehydrogenase CH46_2938 ENOG4105I93 response regulator CH46_2941 ENOG4105CIY formyltetrahydrofolate deformylase CH46_2944 ENOG4105SKE transcriptional Regulator LysR family CH46_2945 ENOG4105CGK Exodeoxyribonuclease III CH46_2946 ENOG4105M6F mutator MutT protein CH46_2947 ENOG4105MTM Protein of unknown function (DUF1496) CH46_2948 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CH46_2949 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) CH46_2950 ENOG41069NU Nitroreductase CH46_2951 ENOG4105D07 Signal peptide peptidase, SppA CH46_2952 ENOG4105HDK L-asparaginase CH46_2953 ENOG4108RWI nicotinamidase CH46_2954 ENOG4105VUT cytoplasmic protein CH46_2957 ENOG4105DSB aldose 1-epimerase CH46_2958 ENOG4105GNX MltA-interacting MipA family protein CH46_2959 ENOG4105CYN Serine protein kinase CH46_296 ENOG4105CHM Aminotransferase CH46_2962 ENOG4105HEI LysR family (Transcriptional regulator CH46_2963 ENOG4105EUB pirin domain protein CH46_2964 ENOG4105CNH Multidrug resistance protein MdtL CH46_2966 ENOG4105ED1 spovr family CH46_2972 ENOG4105C3J Cysteine desulfurase CH46_2975 ENOG4105UZW Tail fiber assembly protein CH46_299 ENOG4105J12 Multidrug resistance protein mdtN CH46_2990 ENOG4108RS6 transposase CH46_3 ENOG4105E66 phosphoriboisomerase A CH46_300 ENOG4108MI0 Resistance protein CH46_3019 ENOG4105HRS Antitermination protein CH46_302 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CH46_3021 ENOG4105NY2 NinB protein CH46_3027 ENOG4107R08 Integrase CH46_3029 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CH46_3030 ENOG4105CVE Lytic murein transglycosylase CH46_3033 ENOG4107QMS site-determining protein CH46_3034 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) CH46_3035 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) CH46_3036 ENOG4105CEY Amp-dependent synthetase and ligase CH46_3037 ENOG4105Y4Z Outer Membrane Lipoprotein CH46_3038 ENOG41072GX Peptidase M22 Glycoprotease CH46_3039 ENOG4105DVT helicase CH46_304 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component CH46_3040 ENOG4105M4H endoribonuclease L-psp CH46_3043 ENOG4108UHU Aldolase CH46_3045 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CH46_3046 ENOG4106KNT transcriptional regulator CH46_3047 ENOG4105CA9 Pyruvate kinase CH46_3048 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CH46_3049 ENOG4105DR5 peptidase CH46_3050 ENOG4105NXV High-affinity zinc uptake system protein CH46_3052 ENOG4105FAV ABC, transporter CH46_3057 ENOG4108TIT dATP pyrophosphohydrolase CH46_3059 ENOG41081XQ Conserved Protein CH46_306 ENOG4108IJG ABC transporter substrate-binding protein CH46_3060 ENOG4105WJG Glutathione CH46_3064 ENOG4106ZCM YecM protein CH46_3068 ENOG4105CJR Integral membrane protein (MviN CH46_3069 ENOG4105EP9 oxidoreductase CH46_307 ENOG4107KJX Transcriptional regulator CH46_3070 ENOG4105D9U N-acetyltransferase CH46_3072 ENOG4105F3T (LipO)protein CH46_3073 ENOG4107XHZ cytoplasmic chaperone TorD family protein CH46_3076 ENOG4105E2R ROK family CH46_3077 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CH46_3078 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH46_3079 ENOG4108RS6 transposase CH46_308 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 CH46_3081 ENOG4105F38 ABC transporter, permease CH46_3082 ENOG4105EG2 ABC transporter, permease CH46_3086 ENOG4105CHH sulfate transporter CH46_3089 ENOG4105CHH sulfate transporter CH46_3090 ENOG4108RS6 transposase CH46_3092 ENOG41063JG Transcriptional regulator CH46_3093 ENOG4108YY7 Invasion gene expression up-regulator SirB CH46_3094 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CH46_3099 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CH46_3100 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria CH46_3102 ENOG4105C3G gtp-binding protein CH46_3111 ENOG4105ENX hydrolase CH46_3113 ENOG4105GR3 Histidine kinase CH46_3122 ENOG4108WF3 methyltransferase CH46_313 ENOG4105CKT filamentous hemagglutinin CH46_3136 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CH46_3137 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CH46_3138 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CH46_3140 ENOG41090B9 response to stress CH46_3141 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) CH46_3142 ENOG4105CZE histidine utilization repressor CH46_315 ENOG4105CKT filamentous hemagglutinin CH46_3155 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CH46_3156 ENOG4105BZU Histidine kinase CH46_3157 ENOG4105EWV Sodium calcium exchanger membrane region CH46_3158 ENOG4105D5M phosphate starvation-inducible protein CH46_3161 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD CH46_3162 ENOG4105CND Glycosyl transferase, family 2 CH46_3163 ENOG4107BJW polysaccharide deacetylase CH46_3164 ENOG4108TUY outer membrane protein PgaA CH46_3165 ENOG4105H1N peptidase, M24 CH46_3169 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CH46_317 ENOG4105CKT filamentous hemagglutinin CH46_3171 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CH46_3174 ENOG4107SJW iron permease, FTR1 CH46_3176 ENOG4105CSV Glutaminase CH46_3177 ENOG4105MVE transcriptional regulator CH46_3178 ENOG4105C85 amino acid CH46_3179 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CH46_318 ENOG4105CKT filamentous hemagglutinin CH46_3180 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH46_3183 ENOG4107RGD Major Facilitator superfamily CH46_3188 ENOG4105DJG MaoC domain protein dehydratase CH46_3189 ENOG4105CYC Transferase CH46_319 ENOG4105D5K Hemolysin activator protein CH46_3191 ENOG4108Q9V regulatoR CH46_3196 ENOG4105CW0 outer membrane usher protein CH46_3198 ENOG4108MQF Chaperone CH46_32 ENOG4105DFP Integrase CH46_320 ENOG4108M24 von Willebrand factor, type A CH46_3202 ENOG4105EYM Major Facilitator superfamily CH46_3203 ENOG4105BZ1 (ABC) transporter CH46_3206 ENOG4105C0W non-ribosomal peptide synthetase CH46_3210 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CH46_3211 ENOG4107ZSV Receptor CH46_3223 ENOG4108IJ9 (ABC) transporter CH46_3224 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component CH46_3227 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) CH46_3228 ENOG4105FDP GntR family transcriptional regulator CH46_323 ENOG4108M24 von Willebrand factor, type A CH46_3247 ENOG4108WC9 type VI secretion system effector, hcp1 family CH46_3258 ENOG4105WH1 Two component transcriptional regulator luxr family CH46_3259 ENOG4105XVG cytoplasmic protein CH46_326 ENOG4108YK4 Acid-resistance membrane protein CH46_3260 ENOG4105RA2 Membrane CH46_3262 ENOG4108T1M outer membrane protein x CH46_3264 ENOG4105C85 amino acid CH46_3267 ENOG4105DBE peroxidase CH46_327 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CH46_3270 ENOG4105CK7 Sodium proline symporter CH46_3272 ENOG4105C26 Dehydrogenase CH46_3275 ENOG4105CDA abc transporter atp-binding protein CH46_3276 ENOG4105E5Q amino acid AbC transporter CH46_3277 ENOG4105EAB amino acid AbC transporter CH46_3278 ENOG4105K6H D-cysteine desulfhydrase CH46_3279 ENOG4108M9K flagella biosynthesis protein FliZ CH46_3280 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH46_3281 ENOG4105I03 Flagellin CH46_3282 ENOG4105DTS flagellar hook-associated CH46_3283 ENOG4105MQ3 flagellar protein FliS CH46_3286 ENOG4108T5G Adenylate CH46_3287 ENOG4105DHT Metal Dependent Phosphohydrolase CH46_3291 ENOG4105VQ0 flagellar hook-basal body complex protein fliE CH46_3292 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CH46_3293 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CH46_3294 ENOG41090PJ Flagellar assembly protein CH46_3295 ENOG4108JIR Flagellum-specific ATP synthase CH46_3296 ENOG4105GSA Flagellar export protein flij CH46_3297 ENOG4105WF4 Flagellar hook-length control protein CH46_3298 ENOG4107ZI8 flagellar basal body-associated protein flil CH46_3299 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CH46_330 ENOG4108VKG metal-dependent hydrolase CH46_3300 ENOG4105DD5 Flagellar motor switch protein CH46_3302 ENOG4105CN7 Flagellar biosynthetic protein FliP CH46_3303 ENOG4105VS8 Flagellar biosynthetic protein fliq CH46_3304 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CH46_3307 ENOG4108MGF sugar kinase CH46_3308 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CH46_3309 ENOG4105C2J ABC transporter CH46_331 ENOG4105EE0 oxidoreductase CH46_3311 ENOG4105CNN ABC, transporter CH46_3314 ENOG4105DKT Transcriptional regulator CH46_3315 ENOG4105DTJ flagellar hook-associated protein CH46_3316 ENOG4105E1Q flagellar hook-associated protein CH46_3317 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CH46_3320 ENOG4105CGA flagellar basal-body rod protein FlgG CH46_3321 ENOG4108KPB Flagellar basal-body rod protein FlgF CH46_3322 ENOG4105BZE flagellar hook protein, FlgE CH46_3323 ENOG4105W00 Flagellar hook capping protein CH46_3324 ENOG4108ZC9 flagellar basal-body rod protein flgc CH46_3325 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CH46_3326 ENOG4105CKS Flagella basal body P-ring formation protein flgA CH46_3327 ENOG4105M9M anti-sigma28 factor FlgM CH46_3328 ENOG4105QVD Flagella synthesis protein FlgN CH46_3330 ENOG4108RS6 transposase CH46_3332 ENOG4105W13 flagellar protein CH46_3333 ENOG4105D7B Flagellar biosynthesis protein flha CH46_3334 ENOG4105D00 flagellar biosynthetic protein flhB CH46_3337 ENOG4105NKT exported protein CH46_3339 ENOG4105FXM Copper resistance protein CH46_334 ENOG4108RS6 transposase CH46_3340 ENOG41090A1 ferritin CH46_3341 ENOG4105MPK DNA polymerase III subunit theta CH46_3343 ENOG4105CUG Oligopeptidase b CH46_3346 ENOG4105X2V dna damage-inducible protein CH46_3347 ENOG4105C1J atp-dependent rna helicase CH46_335 ENOG4105P66 Membrane CH46_3350 ENOG4105CRQ synthase (Component I) CH46_3352 ENOG4105EJQ L-serine dehydratase CH46_3353 ENOG4107UWN reductase CH46_3354 ENOG4105EFA 4-hydroxyphenylacetate CH46_3359 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase CH46_336 ENOG4105CTX dehydratase CH46_3360 ENOG4105C26 Dehydrogenase CH46_3363 ENOG4108V8F Transcriptional regulator, MarR family CH46_3364 ENOG4105EE5 Membrane protein terC CH46_3365 ENOG4108EQA pts system CH46_3366 ENOG4105ETZ PTS System CH46_3367 ENOG4105F3R pts system mannose fructose sorbose family iid CH46_337 ENOG4107QZW Altronate oxidoreductase CH46_3371 ENOG4105BZU Histidine kinase CH46_3373 ENOG4105DHI Methyltransferase CH46_3374 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CH46_3375 ENOG4105VEQ Cold shock protein CH46_3378 ENOG4105C85 amino acid CH46_3381 ENOG41064PC CH46_3382 ENOG4105TIK CH46_3383 ENOG4105N4N Protein of unknown function (DUF2766) CH46_3387 ENOG4105BZ1 (ABC) transporter CH46_339 ENOG4105DPW Major facilitator superfamily MFS_1 CH46_3397 ENOG4105M5J Cupin 2, conserved barrel domain protein CH46_3399 ENOG4105CHR reductase CH46_3400 ENOG41061NF Pectate lyase CH46_3401 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component CH46_3402 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component CH46_3404 ENOG4105WEM extracellular solute-binding protein CH46_3405 ENOG4108PU9 oligogalacturonate-specific porin CH46_3406 ENOG4107K5X Membrane-bound metal-dependent hydrolase CH46_3407 ENOG4108ETY sodium dicarboxylate symporter CH46_3408 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH46_3410 ENOG4105CAZ oligogalacturonide lyase CH46_3411 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH46_3412 ENOG4108VEV chaperone CH46_3415 ENOG4108VEV chaperone CH46_3416 ENOG4105H8W Fimbrial protein CH46_3419 ENOG4105CN1 protease CH46_342 ENOG4106W5V Membrane CH46_3421 ENOG4108ZGC gaf domain protein CH46_3422 ENOG4105H2K paraquat-inducible protein a CH46_3423 ENOG4105DY2 Paraquat-inducible protein b CH46_3427 ENOG4105GQR Chaperone CH46_3430 ENOG4105WT8 Protein of unknown function (DUF1480) CH46_3439 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CH46_3442 ENOG4105EUR Domain-Containing protein CH46_3443 ENOG4105EUR Domain-Containing protein CH46_3444 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH46_3445 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) CH46_3446 ENOG4108VYJ response regulator receiver protein CH46_3448 ENOG4105BZU Histidine kinase CH46_345 ENOG4105NE1 Conserved Protein CH46_3451 ENOG4105C8Q Methyl-accepting chemotaxis CH46_3455 ENOG4105WWK YheO domain protein CH46_3457 ENOG4105KME endoribonuclease L-psp CH46_3458 ENOG4105R9B Major Facilitator CH46_3459 ENOG4108V3W Chemotaxis protein, CheW CH46_346 ENOG41090KG Inner membrane protein YqjE CH46_3460 ENOG4105CBS Chea signal transduction histidine kinase CH46_3461 ENOG4105ER2 Ompa motb domain protein CH46_3462 ENOG4107RD7 Flagellar Motor Protein, MotA CH46_3463 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region CH46_3464 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) CH46_3465 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CH46_3466 ENOG4105KT7 mgtC SapB transporter CH46_3467 ENOG4105C8Q Methyl-accepting chemotaxis CH46_3468 ENOG4105C8Q Methyl-accepting chemotaxis CH46_3470 ENOG4105VEQ Cold shock protein CH46_3473 ENOG4105GSJ Inner membrane protein ylaC CH46_3474 ENOG4108XM1 transcriptional regulator AsnC family CH46_3476 ENOG41061EV selenium-binding protein YdfZ CH46_3477 ENOG4105D6F Phosphatase CH46_3479 ENOG4105KVH Transcriptional regulator CH46_348 ENOG4108VBZ doxx family CH46_3480 ENOG4105ECR NmrA family CH46_3481 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor CH46_3483 ENOG4106NDP Transcriptional regulator CH46_3484 ENOG4108HMX isocitrate dehydrogenase (NADP) CH46_3485 ENOG4108R99 pseudouridine synthase CH46_3489 ENOG4107QTF adenylosuccinate lyase CH46_349 ENOG4105CHF Glutathione S-transferase CH46_3491 ENOG4105XJC Two component transcriptional regulator (Winged helix family CH46_3493 ENOG4105EZE Cupin 4 family protein CH46_3495 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CH46_3497 ENOG4105D60 lipoprotein releasing system transmembrane protein CH46_3499 ENOG4105D60 lipoprotein releasing system transmembrane protein CH46_3500 ENOG4108JA2 transcriptioN-repair coupling factor CH46_3501 ENOG4107MBR 17 kDa surface antigen CH46_3507 ENOG4105CEP NADH dehydrogenase CH46_3509 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) CH46_3512 ENOG41090DQ Lipoprotein CH46_3513 ENOG4105K59 histidine triad (HIT) protein CH46_3514 ENOG4105F9E Shikimate 5-dehydrogenase CH46_3515 ENOG4108RS6 transposase CH46_3516 ENOG4105CI1 PTS System CH46_3517 ENOG4105F8V Hydrolase, tatD family CH46_3518 ENOG4107QRG dna polymerase iii CH46_352 ENOG4105M6F mutator MutT protein CH46_3520 ENOG4105HHA aminodeoxychorismate lyase CH46_3521 ENOG4105YAZ 4-amino-4-deoxychorismate lyase CH46_3522 ENOG4108RS6 transposase CH46_3523 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH46_3525 ENOG4105CHR reductase CH46_3526 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CH46_3529 ENOG4105VGS 50s ribosomal protein l32 CH46_3530 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein CH46_3532 ENOG4108RS6 transposase CH46_3533 ENOG4105EI2 Pseudouridine synthase CH46_3534 ENOG4107QQB Ribonuclease E CH46_3536 ENOG41067V3 Antibiotic biosynthesis monooxygenase CH46_3540 ENOG4105PVA Biofilm formation regulatory protein BssS CH46_3541 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) CH46_3545 ENOG4108TSE Transferase CH46_3546 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CH46_3548 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CH46_3549 ENOG4108KX4 response regulator CH46_3551 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme CH46_3555 ENOG4105UQX Mate efflux family protein CH46_3559 ENOG4105DIA mandelate racemase muconate lactonizing CH46_3561 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CH46_3562 ENOG4105KIR Thiol-disulfide oxidoreductase dcc CH46_3563 ENOG4105CSP Major Facilitator Superfamily CH46_3565 ENOG4105TNG K13735 adhesin invasin CH46_3568 ENOG4105CJB Exodeoxyribonuclease I CH46_3569 ENOG4105CUB amino acid CH46_357 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CH46_3571 ENOG4107SCQ Iron-containing alcohol dehydrogenase CH46_3572 ENOG4105C2J ABC transporter CH46_3573 ENOG4105C2J ABC transporter CH46_3574 ENOG4105CNN ABC, transporter CH46_3576 ENOG4108535 NAD dependent epimerase/dehydratase family CH46_3578 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) CH46_358 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CH46_3580 ENOG4105ECC imidazole-glycerol-phosphate dehydratase CH46_3581 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) CH46_3584 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase CH46_3585 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CH46_3586 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CH46_3587 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CH46_3588 ENOG4105DUU IucA IucC family protein CH46_3589 ENOG4105CNM Receptor CH46_359 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) CH46_3590 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CH46_3591 ENOG4105DQ5 transport system permease protein CH46_3592 ENOG4105TVJ transport system, permease CH46_3593 ENOG4105E0A ABC, transporter CH46_3594 ENOG4105DUU IucA IucC family protein CH46_3596 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CH46_3597 ENOG4105DY8 decarboxylase CH46_3598 ENOG4108819 ferric iron reductase CH46_3599 ENOG4105EE5 Membrane protein terC CH46_36 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation CH46_3600 ENOG4108GAE asmA family CH46_3603 ENOG4105D1F ATP-binding protein CH46_3605 ENOG4108RS6 transposase CH46_3611 ENOG4105E5W Transporter CH46_3613 ENOG41067MG lrgb family CH46_3616 ENOG4107GZ4 SanA protein CH46_3617 ENOG4108HWV )-transporter CH46_3620 ENOG4105DHF Membrane CH46_3622 ENOG4105CBP Major Facilitator CH46_3623 ENOG4105EGI Transcriptional regulator CH46_3628 ENOG4105ENT Efflux transporter rnd family, mfp subunit CH46_3629 ENOG4105C19 ABC transporter CH46_363 ENOG4105CNI cell division protein FtsW CH46_3631 ENOG4105CVM Molybdenum cofactor synthesis domain protein CH46_3632 ENOG4105D06 uba thif-type nad fad binding protein CH46_3635 ENOG4105C5H ABC transporter CH46_3654 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH46_3656 ENOG4105CDV Ompa motb domain protein CH46_366 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) CH46_3662 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CH46_3663 ENOG41062T2 Acyl carrier protein CH46_3665 ENOG4105CHR reductase CH46_3666 ENOG4108KQ6 Enoyl-CoA hydratase CH46_3668 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase CH46_3669 ENOG4105CHR reductase CH46_367 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CH46_3670 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH46_3671 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) CH46_3678 ENOG4108BUD transposase CH46_368 ENOG4105CJN penicillin-binding protein CH46_3680 ENOG4108Z0T Part of a sulfur-relay system (By similarity) CH46_3684 ENOG4105K4P CoA-binding domain protein CH46_3685 ENOG4108Q67 UPF0319 protein CH46_3687 ENOG41088T4 Helicase IV CH46_3688 ENOG410901E Membrane CH46_3689 ENOG4105EM2 membrane CH46_369 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) CH46_3690 ENOG4108RZ1 DNA transformation protein CH46_3692 ENOG4105UYK outer membrane protein a CH46_3693 ENOG4108RS6 transposase CH46_3695 ENOG4105DAN ATP-dependent protease CH46_3698 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH46_37 ENOG4105WJ3 XRE family Transcriptional regulator CH46_3703 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH46_3704 ENOG4108RS6 transposase CH46_3705 ENOG4108Q2G (LipO)protein CH46_3706 ENOG4105DY2 Paraquat-inducible protein b CH46_3707 ENOG4105F1S paraquat-inducible protein a CH46_3708 ENOG4105C5H ABC transporter CH46_3710 ENOG4105QVC MOSC domain-containing protein CH46_3711 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) CH46_3713 ENOG4105CD8 aminopeptidase N CH46_3717 ENOG4105CGF Aromatic amino acid aminotransferase CH46_3718 ENOG4105C5X domain protein CH46_3719 ENOG4105EAQ (twin-arginine translocation) pathway signal CH46_372 ENOG4108RNS Exports L-alanine (By similarity) CH46_3720 ENOG4105DIT ErfK YbiS YcfS YnhG family protein CH46_3721 ENOG4108RS6 transposase CH46_3723 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) CH46_3724 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) CH46_3725 ENOG4106371 Methyltransferase CH46_3726 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups CH46_3728 ENOG4105W49 UPF0434 protein CH46_3729 ENOG4105VEQ Cold shock protein CH46_373 ENOG4107B7Y DNA-binding transcriptional regulator FruR CH46_3730 ENOG4105E32 cytoplasmic protein CH46_3733 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 CH46_3736 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CH46_374 ENOG4108RS6 transposase CH46_3741 ENOG4105EUR Domain-Containing protein CH46_3741 ENOG4105EUR Domain-Containing protein CH46_3742 ENOG4105HDK L-asparaginase CH46_3743 ENOG4105DDY UPF0142 protein ycaO CH46_3744 ENOG4105TMB Formate nitrite transporter CH46_3745 ENOG4105C6N Formate acetyltransferase CH46_3747 ENOG4105F1A Pyruvate formate-lyase CH46_3748 ENOG4108ISG Major Facilitator CH46_375 ENOG4108ZP8 Acetolactate synthase small subunit CH46_3750 ENOG4105D1H recombination factor protein RarA CH46_3753 ENOG4105CNU cell division protein FtsK CH46_3754 ENOG4105EW9 transcriptional regulator AsnC family CH46_3755 ENOG4105C3M thioredoxin reductase CH46_3756 ENOG4108JJ9 ABC, transporter CH46_3757 ENOG4108JJ8 (ABC) transporter CH46_3759 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) CH46_376 ENOG4105C7K acetolactate synthase CH46_3760 ENOG4108RS6 transposase CH46_3761 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH46_3763 ENOG4105VEQ Cold shock protein CH46_3765 ENOG4105DJY efflux transporter, rnd family, mfp subunit CH46_3766 ENOG4108MJ5 VirK protein CH46_3767 ENOG4105CPB ATP-dependent endonuclease of the OLD family CH46_3768 ENOG4105DWU Membrane CH46_377 ENOG4108IQE Amp-dependent synthetase and ligase CH46_3770 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CH46_3771 ENOG4105C7K acetolactate synthase CH46_3772 ENOG4105C5W Aldolase CH46_3773 ENOG4105CGD Nad-dependent epimerase dehydratase CH46_3774 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CH46_3775 ENOG41064MM (LipO)protein CH46_3776 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) CH46_3777 ENOG4105E5Z arginine transporter ATP-binding subunit CH46_3778 ENOG4106PMH Extracellular solute-binding protein family 3 CH46_3779 ENOG4105GBT ABC transporter CH46_378 ENOG41064T2 transcriptional regulator, lysR family CH46_3780 ENOG4105DMR ABC, transporter CH46_3781 ENOG4108I0N Transporter, RarD family, DMT superfamily protein CH46_3782 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) CH46_3783 ENOG410642S Nicotianamine synthase protein CH46_3784 ENOG4105E0A ABC, transporter CH46_3785 ENOG4105DQ5 transport system permease protein CH46_3790 ENOG4106TNF Periplasmic binding protein CH46_3793 ENOG4106TNF Periplasmic binding protein CH46_3795 ENOG4105RBQ inner membrane protein ybjO CH46_3796 ENOG4105D38 putrescine abc transporter CH46_3797 ENOG4105F38 ABC transporter, permease CH46_3798 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH46_3799 ENOG4107RUE extracellular solute-binding protein family 1 CH46_380 ENOG4108RS6 transposase CH46_3800 ENOG4108RMJ sensory transduction regulator CH46_3801 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress CH46_3802 ENOG41090BQ Glutaredoxin CH46_3803 ENOG4105D0C transport protein CH46_3805 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CH46_3806 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH46_3807 ENOG4107FB0 transcriptional regulator DeoR family CH46_3808 ENOG4105C44 Serine transporter CH46_3809 ENOG4105DZ1 carboxypeptidase CH46_3810 ENOG4108UMI ABC transporter, permease CH46_3812 ENOG4105D01 (LipO)protein CH46_3815 ENOG4108TGY Glutathione S-transferase CH46_3816 ENOG4105D05 Receptor CH46_3818 ENOG4105EHG Permease protein CH46_382 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CH46_3820 ENOG4108IQI permease CH46_3822 ENOG4105DUM transcriptional regulator, lysR family CH46_3823 ENOG4105HMI Membrane CH46_3825 ENOG4108D1K outer membrane usher protein CH46_3826 ENOG4108UIF Chaperone CH46_3829 ENOG4108SGD regulatory protein CH46_3830 ENOG4105DM4 PTS System CH46_3831 ENOG4105DE4 1-phosphofructokinase CH46_3832 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein CH46_3834 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CH46_3835 ENOG4105C2J ABC transporter CH46_3837 ENOG4105E66 phosphoriboisomerase A CH46_3839 ENOG4105C26 Dehydrogenase CH46_3842 ENOG4105CHR reductase CH46_3843 ENOG4105KRS Proteinase inhibitor CH46_3846 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) CH46_3847 ENOG4105DEI Mannitol dehydrogenase CH46_3848 ENOG4107YCY Transcriptional regulator CH46_385 ENOG4105S8Q sugar efflux transporter CH46_3850 ENOG4105CKI cobalamin synthesis protein CH46_3851 ENOG41076MN Phosphoesterase, PA-phosphatase related CH46_3852 ENOG4107TT5 NLP P60 protein CH46_3854 ENOG4105CXC rtn protein CH46_3855 ENOG4105E43 Extracellular solute-binding protein, family 5 CH46_3856 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component CH46_3857 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component CH46_3858 ENOG4108JQ5 ABC transporter CH46_3859 ENOG4105HG6 CH46_3860 ENOG4105C2C drug resistance transporter, Bcr CflA CH46_3861 ENOG4105I08 Pseudouridine synthase CH46_3862 ENOG4105CFI type iii restriction protein res subunit CH46_3864 ENOG4108RS6 transposase CH46_3866 ENOG4105PAN UPF0352 protein CH46_3867 ENOG4105E68 Sulfatase CH46_3870 ENOG4105GMB type VI secretion system effector, hcp1 family CH46_3874 ENOG4105CS2 ec 3.2.1.21 CH46_3876 ENOG4108Q3X Transcriptional regulator CH46_388 ENOG4105S8Q sugar efflux transporter CH46_3880 ENOG4108T86 baseplate J family protein CH46_3888 ENOG4105TKZ Tail Sheath CH46_3892 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CH46_3893 ENOG4105MVE transcriptional regulator CH46_3895 ENOG4105G63 Type III effector Hrp-dependent CH46_3896 ENOG4105HRS Antitermination protein CH46_3898 ENOG4105Y50 Virulence Protein CH46_3901 ENOG4105C8Q Methyl-accepting chemotaxis CH46_3903 ENOG4105CT4 transporter CH46_3904 ENOG4107R6D beta-lactam binding protein AmpH CH46_3907 ENOG4108RS6 transposase CH46_3908 ENOG4108RS6 transposase CH46_3909 ENOG4105FCK Membrane CH46_391 ENOG4105DP9 ABC transporter CH46_3911 ENOG4106UW1 Major Facilitator superfamily CH46_3912 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CH46_3913 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CH46_3914 ENOG41068CG regulatoR CH46_3915 ENOG4105BZU Histidine kinase CH46_3916 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH46_3918 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH46_3919 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH46_392 ENOG4106SMU thiamine transporter membrane protein CH46_3920 ENOG4105XPH Ferredoxin CH46_3923 ENOG4105E0U tyrosine-specific transport protein CH46_3924 ENOG4108UII YfaZ family CH46_3925 ENOG4105CH6 catalase CH46_3926 ENOG4105DVT helicase CH46_3928 ENOG4105FDR Membrane CH46_3930 ENOG4105CXN decarboxylase CH46_3931 ENOG4105D5Q Arginine ornithine antiporter CH46_3932 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component CH46_3933 ENOG4108IJ8 ABC transporter CH46_3934 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component CH46_3937 ENOG4105KHC sulfurtransferase CH46_394 ENOG4108KF1 Membrane CH46_3940 ENOG4108IV0 ABC, transporter CH46_3941 ENOG4108JJB ABC transporter CH46_3942 ENOG4105CNN ABC, transporter CH46_3943 ENOG4105C32 Amino acid ABC transporter (Permease) CH46_3945 ENOG4108W15 Protein of unknown function (DUF1456) CH46_3948 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein CH46_395 ENOG4105CQ2 DNA polymerase CH46_3950 ENOG4105Y3U Transglycosylase-associated protein CH46_3952 ENOG4105N1F Hnh endonuclease CH46_3954 ENOG4105CXG d-lactate dehydrogenase CH46_3955 ENOG41061WM D-Alanyl-D-Alanine CH46_3957 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) CH46_3959 ENOG4108RS6 transposase CH46_3960 ENOG4105EAA nucleoside CH46_3961 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) CH46_3963 ENOG4105CN8 Transcriptional regulator CH46_3964 ENOG4105C94 Transporter CH46_3968 ENOG4108RS6 transposase CH46_3969 ENOG4105HFZ Membrane CH46_3970 ENOG4108ZAF Molybdopterin CH46_3971 ENOG4105M00 molybdopterin converting factor, subunit 1 CH46_3973 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CH46_3975 ENOG4105CHW UPF0052 protein CH46_3976 ENOG4105VYA Uncharacterized conserved protein (DUF2132) CH46_3977 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) CH46_3978 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CH46_3979 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CH46_3980 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CH46_3985 ENOG4108K4B hydrolase CH46_3987 ENOG4105E0C molybdate abc transporter CH46_3988 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CH46_3989 ENOG410680R Protein of unknown function (DUF2592) CH46_3990 ENOG4105F4R Transcriptional regulator mode CH46_3991 ENOG4105DKW ABC transporter CH46_3994 ENOG4105CMR udp-glucose 4-epimerase CH46_3995 ENOG4105F0Z galactose-1-phosphate uridylyltransferase CH46_3998 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) CH46_4 ENOG4108JQ1 Dehydrogenase CH46_4003 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH46_4005 ENOG4105PGM cation diffusion facilitator family transporter CH46_4006 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CH46_4010 ENOG4105UFD tol-pal system protein YbgF CH46_4011 ENOG4105KCK Peptidoglycan-associated lipoprotein CH46_4013 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CH46_4013 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CH46_4014 ENOG4105M8F Biopolymer transport protein exbD tolR CH46_4015 ENOG4105E02 MotA TolQ exbB proton channel CH46_4016 ENOG4107YD3 Thioesterase CH46_4017 ENOG4105KJB cyd operon protein YbgE CH46_4019 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CH46_4020 ENOG4105C4M (Ubiquinol oxidase) subunit I CH46_4021 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CH46_4023 ENOG4105C7S Dehydrogenase CH46_4024 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CH46_4025 ENOG4105E33 succinate dehydrogenase CH46_4027 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein CH46_4028 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit CH46_4029 ENOG4105BZN citrate synthase CH46_4031 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) CH46_4032 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CH46_4033 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH46_4035 ENOG4108Z1B Cyclase dehydrase CH46_4037 ENOG4108RS6 transposase CH46_4038 ENOG4105DFP Integrase CH46_4048 ENOG4105VUH addiction module killer protein CH46_4054 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease CH46_4056 ENOG4108JDX DNA polymerase iii, epsilon subunit CH46_4058 ENOG4105D1A Methyltransferase CH46_4060 ENOG4105E9H Lytic Murein transglycosylase CH46_4063 ENOG4105CV8 reductase CH46_4069 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CH46_407 ENOG4105CS6 Rhs element vgr protein CH46_4071 ENOG4108UMI ABC transporter, permease CH46_4072 ENOG4105D01 (LipO)protein CH46_4073 ENOG4108R8X outer membrane lipoprotein CH46_4074 ENOG4108R96 Methyltransferase, YaeB family CH46_4076 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion CH46_4077 ENOG4108YZN class I peptide chain release factor CH46_4078 ENOG4108VWS Yaeq family CH46_408 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH46_4080 ENOG4105M1T rho-binding antiterminator CH46_4082 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) CH46_4083 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CH46_4085 ENOG4105C0B DNA polymerase III (alpha subunit) CH46_4087 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) CH46_4091 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) CH46_4093 ENOG4105DZP Membrane-associated zinc metalloprotease CH46_4094 ENOG4105KNE Phosphatidate cytidylyltransferase CH46_4095 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) CH46_4101 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CH46_4105 ENOG4105QDK Flavodoxin CH46_4106 ENOG4105DR9 pseudouridine synthase CH46_4107 ENOG4105WP7 tRNA pseudouridine synthase C CH46_4108 ENOG4108RS6 transposase CH46_4111 ENOG4105EWT decarboxylase family CH46_4112 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease CH46_4114 ENOG4105M08 Membrane CH46_4115 ENOG4105ETT transcriptional Regulator, LysR family CH46_4117 ENOG4105C9B Cysteine desulfurase CH46_4118 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) CH46_4119 ENOG4105CUZ uba thif-type nad fad binding protein CH46_4120 ENOG4105CA3 membrane-bound lytic murein transglycosylase CH46_4123 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CH46_4125 ENOG4107QYX exodeoxyribonuclease v alpha CH46_4126 ENOG4107QKA exodeoxyribonuclease V beta CH46_4127 ENOG4107QXK peptidase CH46_4128 ENOG4105DSY exodeoxyribonuclease V, gamma CH46_4135 ENOG4107ZSV Receptor CH46_4136 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) CH46_4137 ENOG4105CFC Transporter CH46_4145 ENOG4105C1P efflux transporter, rnd family, mfp subunit CH46_4147 ENOG4105BZU Histidine kinase CH46_4148 ENOG4105DQ6 Transposase CH46_4150 ENOG4105CT4 transporter CH46_4152 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CH46_4153 ENOG4105DUU IucA IucC family protein CH46_417 ENOG4105D3G Pseudouridine synthase CH46_4172 ENOG4105CDV Ompa motb domain protein CH46_4174 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH46_418 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) CH46_4186 ENOG4105CXN decarboxylase CH46_4187 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH46_4188 ENOG4105C2J ABC transporter CH46_4189 ENOG4105CNN ABC, transporter CH46_4194 ENOG4105CEN a g-specific adenine glycosylase CH46_4196 ENOG41090ED Protein with unknown function (DUF469) CH46_4197 ENOG4105CSV Glutaminase CH46_4198 ENOG4105K33 Periplasmic Protein CH46_4199 ENOG4105K33 Periplasmic Protein CH46_420 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) CH46_4200 ENOG4105EUK rtx toxin RtxA CH46_4201 ENOG4105CSA Coproporphyrinogen iii oxidase CH46_4202 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) CH46_4204 ENOG4108VIA integral membrane protein CH46_4205 ENOG4105II7 pyrroline-5-carboxylate reductase CH46_4206 ENOG4105DFA alanine racemase domain protein CH46_4207 ENOG4105CZX twitching motility protein CH46_4209 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) CH46_421 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) CH46_4212 ENOG4105D7Z glutathione synthase CH46_4213 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CH46_4214 ENOG4105RWS endonuclease I CH46_4215 ENOG4105GPY SprT protein CH46_4218 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) CH46_4220 ENOG4108K0D peptidase, M48 CH46_4221 ENOG4105CV1 Transketolase (EC 2.2.1.1) CH46_4222 ENOG4108RS6 transposase CH46_4227 ENOG4105D2N Aldolase CH46_4228 ENOG4105D64 Mechanosensitive ion channel CH46_4235 ENOG4106J5W DNA polymerase III (alpha subunit) CH46_4238 ENOG4105UZW Tail fiber assembly protein CH46_4240 ENOG4108X9F tail fiber protein CH46_4240 ENOG4108X9F tail fiber protein CH46_4247 ENOG4108NYK Tape measure protein CH46_426 ENOG4108RS6 transposase CH46_4265 ENOG4105FA0 parb-like partition protein CH46_4266 ENOG4105FA0 parb-like partition protein CH46_4267 ENOG4105CB5 ATP-dependent DNA helicase recG CH46_427 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) CH46_4276 ENOG4108RS6 transposase CH46_4282 ENOG4105D2X ABC transporter substrate-binding protein CH46_4284 ENOG4106JVB Replication Protein CH46_429 ENOG4105DWK Membrane CH46_4292 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) CH46_4294 ENOG4105C2M dna polymerase I CH46_430 ENOG4105N14 lysine exporter protein LysE YggA CH46_4300 ENOG4106J5W DNA polymerase III (alpha subunit) CH46_4303 ENOG4105FEQ ParB domain protein nuclease CH46_4307 ENOG41073YN Protein of unknown function (DUF1380) CH46_431 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CH46_4312 ENOG4106RMF ParB family CH46_4318 ENOG4108RS6 transposase CH46_432 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CH46_4322 ENOG4105EKQ RNA-directed DNA polymerase CH46_4323 ENOG4105EQR Transposase IS116 IS110 IS902 CH46_4325 ENOG4106PHM regulatory protein CH46_4326 ENOG4108UIF Chaperone CH46_4328 ENOG4108D1K outer membrane usher protein CH46_434 ENOG4108RS6 transposase CH46_436 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase CH46_4373 ENOG4105CMM transposase CH46_4375 ENOG4105CMM transposase CH46_4384 ENOG4106CQM replication CH46_4385 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) CH46_439 ENOG4105DTN riboflavin biosynthesis protein ribF CH46_4394 ENOG4105D13 transposase CH46_4396 ENOG4108C33 Resolvase CH46_4400 ENOG4105CMM transposase CH46_4407 ENOG4105CMM transposase CH46_441 ENOG41063Z6 transcriptional regulator, lysR family CH46_4413 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB CH46_4414 ENOG4105EZN Cobyrinic acid ac-diamide synthase CH46_4428 ENOG4105XUP Phage derived protein Gp49-like (DUF891) CH46_445 ENOG4106HK8 GPR1 FUN34 yaaH family protein CH46_448 ENOG4108RIR Molybdenum cofactor biosynthesis protein CH46_456 ENOG41065U4 response regulator CH46_457 ENOG4108RH0 Crea protein CH46_460 ENOG4105UEI Transcriptional Regulator AraC Family CH46_461 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) CH46_463 ENOG4107SC1 transglycosylase CH46_466 ENOG4108KHX Diguanylate cyclase CH46_467 ENOG41090EK ompa motb domain protein CH46_468 ENOG4105C5H ABC transporter CH46_469 ENOG4105C5H ABC transporter CH46_471 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase CH46_472 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CH46_473 ENOG4105EAC phosphoserine phosphatase CH46_474 ENOG41062Z9 Membrane CH46_479 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH46_480 ENOG4105D9N nucleoside CH46_481 ENOG4105EYA deoxyribonuclease CH46_482 ENOG4108NRW Phospholipase, patatin family CH46_484 ENOG4105K3G Periplasmic Protein CH46_486 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CH46_487 ENOG4108WPU DNA polymerase III subunit psi CH46_490 ENOG4105YBH Protein of unknown function (DUF1435) CH46_491 ENOG4105BZU Histidine kinase CH46_494 ENOG4105BZS acriflavin resistance protein CH46_495 ENOG410624X efflux transporter, rnd family, mfp subunit CH46_498 ENOG4105DKP glycosyl transferase, family 9 CH46_5 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CH46_500 ENOG4105DKT Transcriptional regulator CH46_501 ENOG4105DKT Transcriptional regulator CH46_508 ENOG4105RI1 glycoprotein receptor CH46_509 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CH46_510 ENOG4105DM4 PTS System CH46_511 ENOG4108YRF PTS System CH46_512 ENOG4106R3P AraC family transcriptional regulator CH46_513 ENOG4108XCZ PTS System CH46_515 ENOG4108M3P Membrane CH46_527 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 CH46_531 ENOG4105WSB biofilm stress and motility protein A CH46_532 ENOG4105CSU acyl-Coa dehydrogenase CH46_533 ENOG4105C2N RNA methyltransferase TrmH family group 3 CH46_534 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CH46_538 ENOG4105EPW hflc protein CH46_539 ENOG4107QJR hflk protein CH46_54 ENOG4105NTW Transcriptional regulator CH46_540 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CH46_544 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CH46_545 ENOG4105K8N protein family UPF0079, ATPase CH46_546 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) CH46_547 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CH46_55 ENOG4108UY0 (LipO)protein CH46_550 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) CH46_553 ENOG4105EGS Mechanosensitive ion channel CH46_558 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) CH46_559 ENOG4108RS6 transposase CH46_560 ENOG4105KPY Small multidrug resistance protein CH46_562 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CH46_563 ENOG4108ZVF (LipO)protein CH46_568 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH46_57 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH46_571 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH46_572 ENOG4108RC0 Electron transport protein CH46_573 ENOG4105BZ8 glutamate synthase CH46_574 ENOG4108SIC Transcriptional regulator CH46_58 ENOG4105CNN ABC, transporter CH46_588 ENOG4105C0A alcohol dehydrogenase CH46_590 ENOG4108UUM single-stranded DNA-binding protein CH46_591 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CH46_592 ENOG4105MSB protein, conserved in bacteria CH46_593 ENOG4105CGF Aromatic amino acid aminotransferase CH46_594 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CH46_595 ENOG4105CDU Replicative dna helicase CH46_596 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CH46_597 ENOG4105P4Z Phage shock protein G CH46_598 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CH46_599 ENOG4105MYN Zinc uptake regulation protein CH46_601 ENOG41080IJ Diacylglycerol kinase CH46_609 ENOG4108S1B Periplasmic chaperone protein CH46_61 ENOG4107FKK extracellular solute-binding protein family 1 CH46_621 ENOG4105DAX Pfam:DUF2983 CH46_625 ENOG4105D4P Coproporphyrinogen iii oxidase CH46_626 ENOG41090JE Utilization Protein CH46_629 ENOG4107ENK receptor CH46_63 ENOG4105EG2 ABC transporter, permease CH46_630 ENOG4106QJH hemin transport protein CH46_631 ENOG4107R4I Periplasmic binding protein CH46_632 ENOG4105EHG Permease protein CH46_634 ENOG4105C28 cystathionine CH46_635 ENOG4105C44 Serine transporter CH46_636 ENOG4105EQ2 LysR family Transcriptional regulator CH46_637 ENOG4105KSU Redox protein CH46_638 ENOG41066VF YeeE YedE family protein CH46_639 ENOG4108IUF type iii secretion CH46_640 ENOG4108TN6 type iii secretion CH46_641 ENOG41083GP type iii secretion CH46_642 ENOG4108HHI Type III secretion system protein CH46_643 ENOG41063Q7 Type III secretion system protein CH46_646 ENOG4108JIR Flagellum-specific ATP synthase CH46_65 ENOG4105C4C beta-galactosidase CH46_658 ENOG4105BZU Histidine kinase CH46_659 ENOG4105WH1 Two component transcriptional regulator luxr family CH46_66 ENOG4105CI1 PTS System CH46_660 ENOG4105CK2 sodium dicarboxylate symporter CH46_662 ENOG41062QD Membrane CH46_669 ENOG4108Z0R Transferase CH46_672 ENOG4108WI1 Dna topoisomerase CH46_674 ENOG4105C79 DNA protecting protein DprA CH46_678 ENOG4105C1A potassium transporter peripheral membrane CH46_68 ENOG4105ETE Transcriptional regulator (LacI family CH46_680 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system CH46_681 ENOG4105W1Y Transcriptional regulator CH46_684 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) CH46_687 ENOG41067V7 50S ribosomal protein L36 CH46_688 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CH46_690 ENOG4105VPB 50S ribosomal protein L30 CH46_699 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal CH46_70 ENOG4105DPW Major facilitator superfamily MFS_1 CH46_701 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) CH46_702 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) CH46_704 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) CH46_71 ENOG4105ETE Transcriptional regulator (LacI family CH46_712 ENOG4108RS6 transposase CH46_715 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) CH46_720 ENOG4105WWK YheO domain protein CH46_721 ENOG4108V1T peptidylprolyl cis-trans isomerase CH46_723 ENOG4108YZY peptidylprolyl cis-trans isomerase CH46_724 ENOG4105VKU nucleicacid-binding protein CH46_727 ENOG4105C5H ABC transporter CH46_728 ENOG4105C5H ABC transporter CH46_729 ENOG4105K64 Glycosyl transferase, family 2 CH46_731 ENOG4105E2B Taurine dioxygenase CH46_732 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CH46_734 ENOG4106FTQ Taurine ABC transporter, periplasmic CH46_736 ENOG4105DNZ Alpha Beta Hydrolase CH46_738 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) CH46_74 ENOG4105D2N Aldolase CH46_740 ENOG4108UKZ OsmC family CH46_742 ENOG410613R integral membrane protein, YccS YhfK family CH46_743 ENOG4105C8Y Acetylornithine aminotransferase CH46_745 ENOG4105D7A ATP-binding protein CH46_746 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CH46_747 ENOG4105F8D glycoside hydrolase family 4 CH46_750 ENOG4105F8D glycoside hydrolase family 4 CH46_751 ENOG41060NJ transcriptional regulator CH46_754 ENOG4105DZC cytosine deaminase CH46_755 ENOG4107QZF nitrite reductase NADPH large subunit CH46_756 ENOG4105WZK nitrite reductase NADPH small subunit CH46_757 ENOG4107V9H nitrite transporter CH46_759 ENOG4105C31 Tryptophanyl-tRNA synthetase CH46_76 ENOG4105ENH Sulfatase CH46_760 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) CH46_761 ENOG4105DJV ribulose-phosphate 3-epimerase CH46_766 ENOG4105E4G Type IV pilus CH46_77 ENOG4105C4X radical SAM domain protein CH46_771 ENOG4108JQC penicillin-binding protein 1A CH46_772 ENOG4107RK2 ADP-ribose diphosphatase NudE CH46_774 ENOG4105DQY intracellular growth attenuator CH46_775 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 CH46_776 ENOG4105VEJ Heat shock protein CH46_779 ENOG4105E0F Histidine kinase CH46_780 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH46_781 ENOG4108RRZ Transcription elongation factor GreB CH46_782 ENOG4105BZM domain protein CH46_783 ENOG4105XFK Ferrous iron transport protein A CH46_784 ENOG4105CE1 Ferrous iron transport protein b CH46_786 ENOG4105RID UPF0379 protein yhcN CH46_788 ENOG4105MJ2 Competence protein CH46_79 ENOG4105CHR reductase CH46_790 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) CH46_791 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CH46_792 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CH46_794 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) CH46_796 ENOG4105E98 transcriptional regulator DeoR family CH46_798 ENOG4105DQ6 Transposase CH46_799 ENOG4105SYT Methylenetetrahydrofolate reductase CH46_8 ENOG4107RAQ aminopeptidase CH46_80 ENOG4105CE4 GlcNAc 6-P deacetylase CH46_800 ENOG4105CFH Aspartokinase CH46_801 ENOG4105C28 cystathionine CH46_802 ENOG4105C28 cystathionine CH46_804 ENOG4108Z12 YiaAB two helix domain-containing protein CH46_806 ENOG4105C25 Primosomal protein n' CH46_808 ENOG4105ETE Transcriptional regulator (LacI family CH46_809 ENOG41063M6 Cell Division Protein CH46_81 ENOG4108YTN IIa component CH46_812 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CH46_816 ENOG4108MBX Secretion Protein CH46_82 ENOG4105F3R pts system mannose fructose sorbose family iid CH46_820 ENOG4108JJA ABC, transporter CH46_821 ENOG4108RS6 transposase CH46_823 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CH46_824 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CH46_825 ENOG4105CBT Fructose-1,6-bisphosphatase CH46_826 ENOG4105DP0 ferredoxin-NADP reductase CH46_827 ENOG4108VTS Membrane CH46_828 ENOG4105EBK exported protein CH46_83 ENOG4105ETZ PTS System CH46_830 ENOG4107F9Y LysR family transcriptional regulator CH46_832 ENOG4105JSC dimethylmenaquinone methyltransferase CH46_833 ENOG4107QPK )-transporter CH46_835 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein CH46_84 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB CH46_840 ENOG4105FMW periplasmic CH46_841 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH46_842 ENOG4105E0F Histidine kinase CH46_843 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CH46_844 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CH46_845 ENOG4105D7W serine acetyltransferase CH46_848 ENOG4105VW4 glutaredoxin 3 CH46_849 ENOG4107YZP Rhodanese domain protein CH46_85 ENOG4105E70 isomerase CH46_851 ENOG41063SB peptidase CH46_852 ENOG4105PXI polysaccharide deacetylase CH46_853 ENOG4105PXI polysaccharide deacetylase CH46_855 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CH46_857 ENOG4105XA0 heptosyltransferase ii CH46_858 ENOG4105D16 lipopolysaccharide heptosyltransferase i CH46_859 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase CH46_86 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of CH46_863 ENOG4105W0E 50S ribosomal protein L33 CH46_866 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CH46_87 ENOG4105E98 transcriptional regulator DeoR family CH46_871 ENOG4105DSJ YicC domain protein CH46_872 ENOG4105EN6 Membrane CH46_873 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) CH46_876 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CH46_877 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase CH46_878 ENOG4105CB5 ATP-dependent DNA helicase recG CH46_879 ENOG4105D6U Sodium Glutamate Symporter CH46_88 ENOG4105CBG Sulfatase CH46_880 ENOG4105C2W permease CH46_881 ENOG4105JV1 AsmA family CH46_882 ENOG4105SUU thioesterase domain CH46_886 ENOG4107S2Z UPF0761 membrane protein CH46_887 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 CH46_889 ENOG4105C5F glutamine synthetase CH46_89 ENOG4108RS6 transposase CH46_890 ENOG4105CUX Signal transduction histidine kinase CH46_891 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH46_892 ENOG4105D4P Coproporphyrinogen iii oxidase CH46_895 ENOG4108RS6 transposase CH46_896 ENOG4105C2M dna polymerase I CH46_897 ENOG4108Z33 Thiol disulfide Interchange Protein CH46_898 ENOG4105E27 serine threonine protein kinase CH46_899 ENOG4105PC1 Conserved Protein CH46_9 ENOG4105D0A hydroxylase CH46_901 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b CH46_907 ENOG4107EJG GntR family transcriptional regulator CH46_909 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH46_910 ENOG4108RVA ribokinase CH46_916 ENOG4108VVK transcriptional Regulator, AsnC CH46_917 ENOG4105QTB Flavodoxin CH46_920 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation CH46_922 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) CH46_930 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CH46_931 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) CH46_932 ENOG4105C8U phosphate abc transporter CH46_933 ENOG4105E2Z phosphate ABC transporter (Permease CH46_937 ENOG4106PMH Extracellular solute-binding protein family 3 CH46_938 ENOG4105EAD ABC transporter CH46_939 ENOG4105DRP amino acid AbC transporter CH46_940 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 CH46_941 ENOG4105C7N Xanthine uracil vitamin C permease CH46_946 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CH46_949 ENOG4105VG0 50S ribosomal protein l34 CH46_952 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CH46_953 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) CH46_954 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH46_955 ENOG410667J hydrolase CH46_958 ENOG4105DQ6 Transposase CH46_96 ENOG4107B2H carbonic anhydrase CH46_962 ENOG4105C7B Threonine dehydratase CH46_963 ENOG4105D99 atp gtp-binding protein CH46_964 ENOG4105D99 atp gtp-binding protein CH46_965 ENOG4105R2A (LipO)protein CH46_969 ENOG4105JKW Valine--pyruvate aminotransferase CH46_971 ENOG4107T9C Alpha amylase catalytic region CH46_974 ENOG4108ZG0 Ompa motb domain protein CH46_976 ENOG4108R3E Dna-3-methyladenine glycosylase i CH46_980 ENOG4106JH6 (LipO)protein CH46_981 ENOG4105CTS PTS system mannitol-specific CH46_983 ENOG4105E61 Mannitol repressor protein CH46_985 ENOG4108YYI Protein of unknown function (DUF2810) CH46_989 ENOG4105C8Q Methyl-accepting chemotaxis CH46_990 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CH46_992 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH46_993 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH46_994 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CH46_995 ENOG4108MG3 formate dehydrogenase