locus-tag	class	description
EGX46_00005	COG0515	serine threonine protein kinase
EGX46_00060	COG5599	Phosphatase
EGX46_00065	COG1317	bacterial-type flagellum organization
EGX46_00075	COG4669	(LipO)protein
EGX46_00125	COG2207	Transcriptional regulator
EGX46_00135	COG4792	protein secretion
EGX46_00140	COG4791	protein targeting
EGX46_00145	COG4794	Type iii secretion
EGX46_00150	COG4790	Type iii secretion
EGX46_00155	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGX46_00200	COG4789	Type iii secretion
EGX46_00220	COG0457	Tetratricopeptide repeat
EGX46_00245	COG4886	Leucine-rich repeat (LRR) protein
EGX46_00255	COG3328	transposase activity
EGX46_00280	COG3177	Filamentation induced by cAMP protein fic
EGX46_00315	COG1192	Involved in chromosome partitioning
EGX46_00320	COG1475	DNA binding
EGX46_00335	COG3609	addiction module antidote protein, CC2985 family
EGX46_00345	COG5599	Phosphatase
EGX46_00530	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGX46_00585	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGX46_00635	COG1309	transcriptional regulator
EGX46_00645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_00645	COG0493	'glutamate synthase
EGX46_00650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_00655	COG3383	formate dehydrogenase (NAD+) activity
EGX46_00670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGX46_00715	COG2076	Multidrug Resistance protein
EGX46_00720	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EGX46_00730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX46_00735	COG1053	succinate dehydrogenase
EGX46_00750	COG1511	domain protein
EGX46_00750	COG3264	Mechanosensitive ion channel
EGX46_00770	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGX46_00790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX46_00795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGX46_00795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX46_00800	COG0802	atpase or kinase
EGX46_00805	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX46_00825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX46_00830	COG0330	HflC and HflK could
EGX46_00835	COG0330	HflC and HflK could
EGX46_00840	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EGX46_00855	COG0557	exoribonuclease II activity
EGX46_00860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX46_00865	COG1960	acyl-CoA dehydrogenase activity
EGX46_00870	COG3650	response to hydrogen peroxide
EGX46_00895	COG1401	restriction endodeoxyribonuclease activity
EGX46_00955	COG4269	membrane
EGX46_00965	COG2207	Transcriptional regulator
EGX46_00970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_00975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_00980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_00985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_00985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX46_00985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_01040	COG0859	PFAM glycosyl transferase family 9
EGX46_01060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_01065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_01090	COG3706	GGDEF domain
EGX46_01110	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EGX46_01115	COG0456	acetyltransferase
EGX46_01125	COG2823	Periplasmic or secreted lipoprotein
EGX46_01135	COG4667	esterase of the alpha-beta hydrolase superfamily
EGX46_01140	COG0084	hydrolase, TatD family'
EGX46_01145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX46_01150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX46_01170	COG3726	membrane protein affecting hemolysin expression
EGX46_01175	COG0560	Phosphoserine phosphatase
EGX46_01215	COG2271	Major facilitator Superfamily
EGX46_01225	COG1943	Transposase
EGX46_01235	COG2831	hemolysin activation secretion protein
EGX46_01245	COG0747	negative chemotaxis
EGX46_01250	COG0601	transmembrane transport
EGX46_01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_01260	COG0444	Belongs to the ABC transporter superfamily
EGX46_01265	COG4608	Belongs to the ABC transporter superfamily
EGX46_01270	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGX46_01275	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGX46_01280	COG2200	EAL domain
EGX46_01280	COG2199	diguanylate cyclase activity
EGX46_01285	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX46_01305	COG0612	Peptidase, M16
EGX46_01310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_01315	COG1942	4-Oxalocrotonate Tautomerase
EGX46_01320	COG2200	EAL domain
EGX46_01325	COG2982	Protein involved in outer membrane biogenesis
EGX46_01330	COG2134	cdp-diacylglycerol pyrophosphatase
EGX46_01335	COG1295	ribonuclease BN
EGX46_01360	COG1929	Belongs to the glycerate kinase type-1 family
EGX46_01365	COG2610	gluconate transmembrane transporter activity
EGX46_01375	COG3835	regulator
EGX46_01380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX46_01385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGX46_01390	COG0339	signal peptide processing
EGX46_01410	COG0589	response to stress
EGX46_01420	COG1943	Transposase
EGX46_01425	COG0306	phosphate transporter
EGX46_01430	COG2081	HI0933 family
EGX46_01445	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_01450	COG1879	ABC-type sugar transport system periplasmic component
EGX46_01460	COG0191	fructose-bisphosphate aldolase activity
EGX46_01470	COG0745	RESPONSE REGULATOR receiver
EGX46_01485	COG1741	Belongs to the pirin family
EGX46_01490	COG1609	Transcriptional regulator
EGX46_01495	COG2610	gluconate transmembrane transporter activity
EGX46_01500	COG3265	gluconokinase activity
EGX46_01520	COG2095	MarC family integral membrane protein
EGX46_01525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX46_01555	COG3275	phosphorelay sensor kinase activity
EGX46_01580	COG0058	SHG alpha-glucan phosphorylase activity
EGX46_01585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX46_01635	COG0583	DNA-binding transcription factor activity
EGX46_01640	COG1741	Belongs to the pirin family
EGX46_01650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX46_01670	COG2823	Periplasmic or secreted lipoprotein
EGX46_01680	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EGX46_01690	COG5002	protein histidine kinase activity
EGX46_01690	COG2198	Histidine kinase
EGX46_01690	COG0784	Response regulator, receiver
EGX46_01700	COG1242	4 iron, 4 sulfur cluster binding
EGX46_01705	COG0067	glutamate synthase
EGX46_01705	COG0069	glutamate synthase activity
EGX46_01705	COG0070	glutamate synthase
EGX46_01710	COG0493	'glutamate synthase
EGX46_01720	COG2969	positive regulation of protein catabolic process
EGX46_01725	COG0625	glutathione transferase activity
EGX46_01745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGX46_01750	COG3105	Protein conserved in bacteria
EGX46_01755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX46_01760	COG1943	Transposase
EGX46_01765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX46_01775	COG5007	Belongs to the BolA IbaG family
EGX46_01780	COG3113	response to antibiotic
EGX46_01785	COG2854	intermembrane phospholipid transfer
EGX46_01790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX46_01795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGX46_01800	COG1127	ABC transporter
EGX46_01805	COG0530	calcium, potassium:sodium antiporter activity
EGX46_01810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGX46_01810	COG0517	IMP dehydrogenase activity
EGX46_01815	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGX46_01820	COG3117	lipopolysaccharide transmembrane transporter activity
EGX46_01825	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGX46_01830	COG1137	ATPase activity
EGX46_01835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EGX46_01845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_01860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_01890	COG1609	Transcriptional regulator
EGX46_01895	COG1263	PTS System
EGX46_01895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_01900	COG0366	Alpha amylase catalytic
EGX46_01905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX46_01910	COG3783	Cytochrome b(562)
EGX46_01925	COG0312	modulator of DNA gyrase
EGX46_01935	COG2732	(Barnase) inhibitor
EGX46_01965	COG0583	DNA-binding transcription factor activity
EGX46_02020	COG0312	modulator of DNA gyrase
EGX46_02025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX46_02030	COG3164	Protein of unknown function
EGX46_02035	COG1530	ribonuclease E activity
EGX46_02045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGX46_02050	COG1792	Involved in formation and maintenance of cell shape
EGX46_02055	COG1077	Cell shape determining protein MreB Mrl
EGX46_02060	COG2199	diguanylate cyclase activity
EGX46_02060	COG2200	EAL domain
EGX46_02065	COG0604	alcohol dehydrogenase
EGX46_02070	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGX46_02085	COG0511	ligase activity, forming carbon-carbon bonds
EGX46_02090	COG0439	Biotin carboxylase
EGX46_02095	COG3924	membrane
EGX46_02100	COG4145	pantothenate transmembrane transporter activity
EGX46_02110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX46_02115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGX46_02145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX46_02155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX46_02160	COG3133	Outer membrane lipoprotein
EGX46_02170	COG1278	Cold shock
EGX46_02175	COG1278	Cold shock
EGX46_02180	COG1943	Transposase
EGX46_02195	COG0625	glutathione transferase activity
EGX46_02205	COG1069	ribulokinase activity
EGX46_02215	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_02220	COG1129	ABC transporter
EGX46_02230	COG1560	Kdo2-lipid A biosynthetic process
EGX46_02240	COG0025	NhaP-type Na H and K H
EGX46_02245	COG2252	PERMEase
EGX46_02250	COG3077	Addiction module antitoxin, RelB DinJ family
EGX46_02265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX46_02275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX46_02280	COG0431	NADPH-dependent FMN reductase
EGX46_02290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_02295	COG1869	D-ribose catabolic process
EGX46_02300	COG2207	Transcriptional regulator
EGX46_02300	COG1917	Cupin 2, conserved barrel domain protein
EGX46_02305	COG0673	inositol 2-dehydrogenase activity
EGX46_02345	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX46_02350	COG0250	Participates in transcription elongation, termination and antitermination
EGX46_02385	COG1943	Transposase
EGX46_02410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX46_02420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGX46_02445	COG1515	deoxyribonuclease V activity
EGX46_02450	COG3068	Protein conserved in bacteria
EGX46_02465	COG0151	Belongs to the GarS family
EGX46_02565	COG3501	Rhs element vgr protein
EGX46_02605	COG3047	cAMP biosynthetic process
EGX46_02605	COG2885	chlorophyll binding
EGX46_02625	COG0417	DNA replication proofreading
EGX46_02630	COG0586	Pfam SNARE associated Golgi protein
EGX46_02640	COG1178	ABC-type Fe3 transport system permease component
EGX46_02645	COG4143	(ABC) transporter
EGX46_02680	COG2814	Major facilitator Superfamily
EGX46_02695	COG0473	3-isopropylmalate dehydrogenase activity
EGX46_02705	COG1943	Transposase
EGX46_02725	COG1022	Amp-dependent synthetase and ligase
EGX46_02735	COG0028	Belongs to the TPP enzyme family
EGX46_02745	COG1943	Transposase
EGX46_02755	COG1609	Transcriptional regulator
EGX46_02780	COG3116	cell division
EGX46_02785	COG0768	penicillin binding
EGX46_02790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX46_02795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX46_02810	COG0772	Belongs to the SEDS family
EGX46_02830	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX46_02835	COG0849	cell division
EGX46_02840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX46_02870	COG0494	nUDIX hydrolase
EGX46_02940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGX46_02945	COG2224	Isocitrate lyase
EGX46_02975	COG0527	aspartate kinase activity
EGX46_02990	COG3833	ABC-type maltose transport systems, permease component
EGX46_02995	COG1175	transmembrane transport
EGX46_03080	COG0195	Participates in both transcription termination and antitermination
EGX46_03100	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX46_03110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGX46_03115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX46_03125	COG1534	Rna-binding protein
EGX46_03130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX46_03135	COG2027	D-alanyl-D-alanine carboxypeptidase
EGX46_03140	COG0745	RESPONSE REGULATOR receiver
EGX46_03145	COG0642	Histidine kinase
EGX46_03155	COG0697	spore germination
EGX46_03170	COG0142	geranyltranstransferase activity
EGX46_03180	COG3423	Transcriptional regulator
EGX46_03205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX46_03215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGX46_03220	COG2105	PFAM AIG2 family protein
EGX46_03225	COG2911	Protein conserved in bacteria
EGX46_03230	COG0729	surface antigen
EGX46_03240	COG1253	flavin adenine dinucleotide binding
EGX46_03250	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EGX46_03260	COG0737	Belongs to the 5'-nucleotidase family
EGX46_03270	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX46_03275	COG3061	Opacity-associated protein A
EGX46_03285	COG1943	Transposase
EGX46_03295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGX46_03305	COG0360	Binds together with S18 to 16S ribosomal RNA
EGX46_03315	COG1073	alpha beta
EGX46_03350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGX46_03365	COG1629	transport
EGX46_03390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX46_03395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX46_03395	COG0678	peroxiredoxin activity
EGX46_03475	COG1879	ABC-type sugar transport system periplasmic component
EGX46_03480	COG1129	ABC transporter
EGX46_03485	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_03490	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_03500	COG3085	chromosome segregation
EGX46_03525	COG3978	acetolactate synthase activity
EGX46_03530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX46_03570	COG0583	DNA-binding transcription factor activity
EGX46_03610	COG3121	Chaperone
EGX46_03625	COG3121	Chaperone
EGX46_03640	COG3328	transposase activity
EGX46_03650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX46_03675	COG3118	belongs to the thioredoxin family
EGX46_03680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGX46_03685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX46_03690	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX46_03695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX46_03700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGX46_03705	COG1088	dTDP-glucose 4,6-dehydratase activity
EGX46_03710	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGX46_03715	COG0456	acetyltransferase
EGX46_03720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGX46_03725	COG2244	polysaccharide biosynthetic process
EGX46_03745	COG1113	amino acid transport
EGX46_03780	COG1943	Transposase
EGX46_03790	COG3071	HemY protein
EGX46_03795	COG2959	enzyme of heme biosynthesis
EGX46_03800	COG1587	Uroporphyrinogen-III synthase
EGX46_03815	COG3072	Adenylate cyclase
EGX46_03825	COG5567	small periplasmic lipoprotein
EGX46_03835	COG3159	Protein conserved in bacteria
EGX46_03840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGX46_03845	COG1011	Hydrolase
EGX46_03850	COG0210	DNA helicase
EGX46_03860	COG5441	Belongs to the UPF0261 family
EGX46_03865	COG5564	TIM-barrel signal transduction protein
EGX46_03870	COG0598	Magnesium transport protein CorA
EGX46_03880	COG2050	protein possibly involved in aromatic compounds catabolism
EGX46_03885	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EGX46_03890	COG0514	ATP-dependent DNA helicase (RecQ)
EGX46_03895	COG1280	lysine exporter protein (LysE YggA)
EGX46_03900	COG1280	lysine exporter protein (LysE YggA)
EGX46_03905	COG2267	carboxylic ester hydrolase activity
EGX46_03910	COG0561	phosphatase activity
EGX46_03920	COG0584	glycerophosphoryl diester phosphodiesterase
EGX46_03935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX46_03945	COG0247	lactate metabolic process
EGX46_03955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX46_03970	COG3714	YhhN family
EGX46_03985	COG3776	membrane
EGX46_03990	COG0742	ribosomal rna small subunit methyltransferase
EGX46_04000	COG0552	protein localization to endoplasmic reticulum
EGX46_04000	COG0552	protein localization to endoplasmic reticulum
EGX46_04005	COG2884	Cell division ATP-binding protein ftsE
EGX46_04010	COG2177	Part of the ABC transporter FtsEX involved in
EGX46_04020	COG1943	Transposase
EGX46_04030	COG0683	leucine binding
EGX46_04050	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGX46_04055	COG4177	L-phenylalanine transmembrane transporter activity
EGX46_04060	COG0411	ABC transporter
EGX46_04065	COG0410	ABC transporter
EGX46_04125	COG0584	glycerophosphoryl diester phosphodiesterase
EGX46_04130	COG0679	Auxin Efflux Carrier
EGX46_04140	COG0583	DNA-binding transcription factor activity
EGX46_04150	COG0412	Dienelactone hydrolase
EGX46_04155	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EGX46_04165	COG1966	Carbon starvation protein
EGX46_04170	COG0586	Pfam SNARE associated Golgi protein
EGX46_04175	COG1322	Protein conserved in bacteria
EGX46_04195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX46_04205	COG0805	protein transport
EGX46_04240	COG1575	Belongs to the MenA family. Type 1 subfamily
EGX46_04255	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX46_04260	COG1609	Transcriptional regulator
EGX46_04270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX46_04280	COG4682	membrane
EGX46_04295	COG0460	homoserine dehydrogenase
EGX46_04295	COG0527	aspartate kinase activity
EGX46_04315	COG2211	Major facilitator Superfamily
EGX46_04365	COG2771	luxR family
EGX46_04370	COG3916	Acyl-homoserine-lactone synthase
EGX46_04500	COG1982	Orn Lys Arg decarboxylase major
EGX46_04505	COG1879	ABC-type sugar transport system periplasmic component
EGX46_04510	COG1129	ABC transporter
EGX46_04515	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_04520	COG4774	siderophore transport
EGX46_04545	COG1194	a g-specific adenine glycosylase
EGX46_04555	COG3171	Protein conserved in bacteria
EGX46_04560	COG2066	Belongs to the glutaminase family
EGX46_04570	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EGX46_04570	COG1073	alpha beta
EGX46_04570	COG3064	Membrane
EGX46_04575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX46_04580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGX46_04590	COG0762	integral membrane protein
EGX46_04600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX46_04605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGX46_04610	COG2805	Type II/IV secretion system protein
EGX46_04620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX46_04635	COG0189	ligase activity
EGX46_04640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX46_04645	COG2356	endonuclease I
EGX46_04660	COG1166	arginine decarboxylase activity
EGX46_04670	COG1943	Transposase
EGX46_04685	COG0501	Belongs to the peptidase M48B family
EGX46_04695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGX46_04705	COG1943	Transposase
EGX46_04720	COG0191	fructose-bisphosphate aldolase activity
EGX46_04765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGX46_04770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX46_04775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX46_04800	COG0006	proline dipeptidase activity
EGX46_04805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX46_04810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX46_04850	COG5295	Hep Hag repeat protein
EGX46_04860	COG1272	protein, Hemolysin III
EGX46_04875	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGX46_04885	COG0745	RESPONSE REGULATOR receiver
EGX46_04890	COG2205	protein histidine kinase activity
EGX46_04895	COG4452	Inner membrane protein CreD
EGX46_04900	COG0716	FMN binding
EGX46_04905	COG4974	Belongs to the 'phage' integrase family
EGX46_04910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX46_04915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX46_04955	COG0582	viral genome integration into host DNA
EGX46_04980	COG2944	sequence-specific DNA binding
EGX46_05070	COG1695	Transcriptional regulator
EGX46_05075	COG0791	NLP P60 protein
EGX46_05085	COG1879	ABC-type sugar transport system periplasmic component
EGX46_05090	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_05095	COG1129	ABC transporter
EGX46_05105	COG2182	Extracellular solute-binding protein
EGX46_05110	COG1175	transmembrane transport
EGX46_05115	COG3833	ABC-type maltose transport systems, permease component
EGX46_05120	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EGX46_05125	COG1874	Beta-galactosidase
EGX46_05130	COG1263	PTS System
EGX46_05130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_05150	COG2271	Major facilitator Superfamily
EGX46_05170	COG0191	fructose-bisphosphate aldolase activity
EGX46_05180	COG3119	arylsulfatase activity
EGX46_05185	COG0641	radical SAM
EGX46_05195	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_05205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_05210	COG3716	PTS system mannose fructose sorbose family IID component
EGX46_05215	COG3715	PTS system
EGX46_05220	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_05225	COG2222	sugar isomerase
EGX46_05235	COG1349	DNA-binding transcription factor activity
EGX46_05240	COG3119	arylsulfatase activity
EGX46_05245	COG1943	Transposase
EGX46_05290	COG0288	reversible hydration of carbon dioxide
EGX46_05340	COG2165	general secretion pathway protein
EGX46_05385	COG0840	transmembrane signaling receptor activity
EGX46_05400	COG0583	DNA-binding transcription factor activity
EGX46_05405	COG2814	Major facilitator Superfamily
EGX46_05410	COG0583	DNA-binding transcription factor activity
EGX46_05415	COG0019	diaminopimelate decarboxylase activity
EGX46_05420	COG1609	Transcriptional regulator
EGX46_05450	COG0667	Aldo Keto reductase
EGX46_05520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGX46_05530	COG1074	ATP-dependent DNA helicase activity
EGX46_05535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX46_05545	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX46_05560	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGX46_05565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX46_05570	COG2166	iron-sulfur cluster assembly
EGX46_05575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGX46_05585	COG0583	DNA-binding transcription factor activity
EGX46_05590	COG2363	Small membrane protein
EGX46_05630	COG1611	Belongs to the LOG family
EGX46_05645	COG1943	Transposase
EGX46_05650	COG3098	single-species biofilm formation
EGX46_05655	COG0564	pseudouridine synthase activity
EGX46_05680	COG0024	Methionine aminopeptidase
EGX46_05700	COG1943	Transposase
EGX46_05725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGX46_05730	COG0575	Belongs to the CDS family
EGX46_05735	COG0750	zinc metalloprotease
EGX46_05745	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EGX46_05765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGX46_05775	COG0587	DNA-directed DNA polymerase activity
EGX46_05785	COG0346	lactoylglutathione lyase activity
EGX46_05790	COG0037	tRNA processing
EGX46_05800	COG4568	rho-dependent transcription termination
EGX46_05810	COG4681	YaeQ
EGX46_05820	COG3015	lipoprotein NlpE involved in copper resistance
EGX46_05830	COG1720	tRNA m6t6A37 methyltransferase activity
EGX46_05840	COG1464	Belongs to the NlpA lipoprotein family
EGX46_05845	COG2011	ABC-type metal ion transport system permease component
EGX46_05855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGX46_05890	COG0656	L-ascorbic acid biosynthetic process
EGX46_05910	COG0741	lytic transglycosylase activity
EGX46_05910	COG1388	LysM domain
EGX46_05920	COG2226	methyltransferase
EGX46_05930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX46_05940	COG1953	Uracil, thiamine, allantoin
EGX46_05965	COG3657	addiction module killer protein
EGX46_06025	COG0582	viral genome integration into host DNA
EGX46_06035	COG1943	Transposase
EGX46_06055	COG2867	negative regulation of translational initiation
EGX46_06065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX46_06070	COG0497	DNA recombination
EGX46_06075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX46_06090	COG2009	succinate dehydrogenase
EGX46_06095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGX46_06100	COG1053	succinate dehydrogenase
EGX46_06110	COG0567	Dehydrogenase, E1 component
EGX46_06115	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX46_06125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX46_06130	COG1271	oxidase subunit
EGX46_06135	COG1294	oxidase, subunit
EGX46_06140	COG4890	Cyd operon protein YbgT
EGX46_06145	COG3790	cyd operon protein YbgE
EGX46_06150	COG0824	Thioesterase
EGX46_06155	COG0811	peptide transport
EGX46_06160	COG0848	biopolymer transport protein
EGX46_06165	COG3064	Membrane
EGX46_06165	COG3064	Membrane
EGX46_06175	COG2885	chlorophyll binding
EGX46_06180	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EGX46_06210	COG1230	cation diffusion facilitator family transporter
EGX46_06215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX46_06240	COG0814	amino acid
EGX46_06245	COG1349	DNA-binding transcription factor activity
EGX46_06250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX46_06255	COG0671	phosphoesterase, PA-phosphatase related
EGX46_06270	COG0569	domain protein
EGX46_06270	COG2985	domain, Protein
EGX46_06275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX46_06295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGX46_06300	COG3842	ATPase activity
EGX46_06305	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX46_06310	COG1177	transmembrane transport
EGX46_06325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_06350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_06355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_06360	COG1120	ATPase activity
EGX46_06380	COG4160	amino acid transport
EGX46_06385	COG4215	(ABC) transporter
EGX46_06390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_06395	COG1126	abc transporter atp-binding protein
EGX46_06400	COG1605	Chorismate mutase
EGX46_06410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_06415	COG0702	epimerase
EGX46_06420	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EGX46_06430	COG0028	Belongs to the TPP enzyme family
EGX46_06435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_06445	COG2431	L-lysine efflux transmembrane transporter activity
EGX46_06450	COG3593	DNA synthesis involved in DNA repair
EGX46_06455	COG2990	Protein conserved in bacteria
EGX46_06460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_06470	COG1278	Cold shock
EGX46_06485	COG0542	response to heat
EGX46_06490	COG1943	Transposase
EGX46_06500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGX46_06510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX46_06520	COG0492	ferredoxin-NADP+ reductase activity
EGX46_06530	COG3107	peptidoglycan biosynthetic process
EGX46_06530	COG1674	ftsk spoiiie
EGX46_06540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX46_06555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGX46_06565	COG1882	Formate acetyltransferase
EGX46_06570	COG2116	formate transmembrane transporter activity
EGX46_06575	COG1944	ATP diphosphatase activity
EGX46_06580	COG0252	asparaginase activity
EGX46_06585	COG5295	Hep Hag repeat protein
EGX46_06585	COG5295	Hep Hag repeat protein
EGX46_06610	COG0539	negative regulation of cytoplasmic translation
EGX46_06625	COG0658	competence protein
EGX46_06625	COG2333	competence protein COMEC
EGX46_06670	COG1278	Cold shock
EGX46_06675	COG2835	tetraacyldisaccharide 4'-kinase activity
EGX46_06690	COG3173	Aminoglycoside phosphotransferase
EGX46_06700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGX46_06705	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EGX46_06710	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EGX46_06725	COG1943	Transposase
EGX46_06730	COG2989	Protein conserved in bacteria
EGX46_06735	COG3108	Peptidase M15
EGX46_06740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX46_06750	COG1448	Aminotransferase
EGX46_06770	COG0308	aminopeptidase N
EGX46_06785	COG0633	Ferredoxin
EGX46_06785	COG3217	Mosc domain protein beta barrel domain protein
EGX46_06795	COG0488	(ABC) transporter
EGX46_06800	COG2995	paraquat-inducible protein a
EGX46_06805	COG3008	intermembrane lipid transfer
EGX46_06805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX46_06810	COG3009	Protein conserved in bacteria
EGX46_06820	COG3130	regulation of translation
EGX46_06830	COG1943	Transposase
EGX46_06850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_06865	COG1067	ATP-dependent peptidase activity
EGX46_06875	COG1943	Transposase
EGX46_06880	COG2885	chlorophyll binding
EGX46_06880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGX46_06890	COG3070	regulator of competence-specific genes
EGX46_06895	COG1289	transmembrane transporter activity
EGX46_06900	COG3304	Inner membrane component domain
EGX46_06905	COG0210	DNA helicase
EGX46_06915	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EGX46_06920	COG1832	CoA-binding protein
EGX46_06940	COG2920	part of a sulfur-relay system
EGX46_06965	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_06975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGX46_06980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_06985	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_06990	COG3425	synthase
EGX46_07000	COG1024	Enoyl-CoA hydratase
EGX46_07005	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_07015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX46_07020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGX46_07170	COG0488	(ABC) transporter
EGX46_07180	COG3328	transposase activity
EGX46_07190	COG0303	'Molybdopterin
EGX46_07200	COG1136	(ABC) transporter
EGX46_07230	COG0583	DNA-binding transcription factor activity
EGX46_07235	COG0477	Major facilitator Superfamily
EGX46_07245	COG2311	Membrane
EGX46_07260	COG4211	Belongs to the binding-protein-dependent transport system permease family
EGX46_07265	COG2949	membrane
EGX46_07280	COG1346	cytolysis
EGX46_07290	COG2814	Major facilitator Superfamily
EGX46_07315	COG1943	Transposase
EGX46_07325	COG0489	protein tyrosine kinase activity
EGX46_07340	COG2982	Protein involved in outer membrane biogenesis
EGX46_07345	COG1253	flavin adenine dinucleotide binding
EGX46_07350	COG4114	ferric iron reductase
EGX46_07355	COG0076	glutamate decarboxylase activity
EGX46_07360	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGX46_07375	COG1120	ATPase activity
EGX46_07380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_07385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_07390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX46_07405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX46_07410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX46_07420	COG0140	phosphoribosyl-ATP diphosphatase activity
EGX46_07420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGX46_07435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGX46_07440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGX46_07440	COG0131	Imidazoleglycerol-phosphate dehydratase
EGX46_07450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGX46_07465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_07470	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_07475	COG1129	ABC transporter
EGX46_07480	COG1129	ABC transporter
EGX46_07485	COG0371	Dehydrogenase
EGX46_07495	COG0531	amino acid
EGX46_07505	COG2925	Exonuclease
EGX46_07520	COG3328	transposase activity
EGX46_07525	COG1388	LysM domain
EGX46_07525	COG1470	cell adhesion involved in biofilm formation
EGX46_07530	COG2271	Major facilitator Superfamily
EGX46_07535	COG3011	Protein conserved in bacteria
EGX46_07540	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_07550	COG4948	Mandelate Racemase Muconate Lactonizing
EGX46_07570	COG0534	Mate efflux family protein
EGX46_07590	COG3122	Protein conserved in bacteria
EGX46_07615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGX46_07635	COG2223	nitrite transmembrane transporter activity
EGX46_07640	COG3328	transposase activity
EGX46_07655	COG1943	Transposase
EGX46_07665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX46_07675	COG1686	Belongs to the peptidase S11 family
EGX46_07680	COG0277	FAD linked oxidase domain protein
EGX46_07690	COG1403	HNH endonuclease
EGX46_07700	COG2261	transglycosylase associated protein
EGX46_07710	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EGX46_07725	COG4807	Protein conserved in bacteria
EGX46_07745	COG1122	ATPase activity
EGX46_07750	COG0410	ABC transporter
EGX46_07770	COG2897	thiosulfate sulfurtransferase activity
EGX46_07775	COG1732	Glycine betaine
EGX46_07780	COG1732	Glycine betaine
EGX46_07785	COG1174	glycine betaine transport
EGX46_07790	COG1125	glycine betaine transport
EGX46_07795	COG1174	glycine betaine transport
EGX46_07800	COG0531	amino acid
EGX46_07805	COG1982	Orn Lys Arg decarboxylase major
EGX46_07815	COG0697	spore germination
EGX46_07860	COG0814	amino acid
EGX46_07880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_07905	COG2205	protein histidine kinase activity
EGX46_07905	COG0784	Response regulator, receiver
EGX46_07915	COG2198	Histidine kinase
EGX46_07915	COG0642	Histidine kinase
EGX46_07920	COG2198	Histidine kinase
EGX46_07920	COG0642	Histidine kinase
EGX46_07925	COG2223	nitrite transmembrane transporter activity
EGX46_07930	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGX46_07960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGX46_08010	COG3395	kinase activity
EGX46_08015	COG0235	Class ii aldolase
EGX46_08020	COG1349	DNA-binding transcription factor activity
EGX46_08025	COG3622	Belongs to the hyi family
EGX46_08045	COG4386	tail sheath protein
EGX46_08085	COG3299	homolog of phage Mu protein gp47
EGX46_08105	COG1737	Transcriptional regulator
EGX46_08110	COG2723	6-phospho-beta-galactosidase activity
EGX46_08160	COG3083	sulfuric ester hydrolase activity
EGX46_08165	COG3082	Protein of unknown function (DUF1414)
EGX46_08175	COG1943	Transposase
EGX46_08190	COG1061	Type III restriction enzyme res subunit
EGX46_08195	COG1187	pseudouridine synthase activity
EGX46_08200	COG2814	Major facilitator Superfamily
EGX46_08210	COG4172	Belongs to the ABC transporter superfamily
EGX46_08215	COG4239	(ABC) transporter, permease
EGX46_08220	COG4174	ABC transporter (Permease)
EGX46_08225	COG4166	transmembrane transport
EGX46_08230	COG2200	EAL domain
EGX46_08235	COG0791	NLP P60 protein
EGX46_08240	COG0671	phosphoesterase, PA-phosphatase related
EGX46_08245	COG0523	cobalamin synthesis protein
EGX46_08255	COG2186	Transcriptional regulator
EGX46_08260	COG0246	Mannitol dehydrogenase
EGX46_08285	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_08315	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGX46_08325	COG1129	ABC transporter
EGX46_08330	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_08335	COG0494	nUDIX hydrolase
EGX46_08345	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX46_08350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_08350	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGX46_08350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_08355	COG3710	Transcriptional regulator
EGX46_08370	COG3121	Chaperone
EGX46_08375	COG3188	usher protein
EGX46_08385	COG2855	membrane
EGX46_08390	COG0583	DNA-binding transcription factor activity
EGX46_08395	COG0833	amino acid
EGX46_08405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_08415	COG4771	TonB-dependent receptor
EGX46_08425	COG0625	glutathione transferase activity
EGX46_08450	COG2011	ABC-type metal ion transport system permease component
EGX46_08490	COG2017	converts alpha-aldose to the beta-anomer
EGX46_08505	COG1085	galactose-1-phosphate uridylyltransferase
EGX46_08510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX46_08520	COG1119	ATPase activity
EGX46_08525	COG3585	molybdate ion transport
EGX46_08525	COG2005	Transcriptional regulator
EGX46_08535	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGX46_08540	COG4149	molybdate abc transporter
EGX46_08550	COG0561	phosphatase activity
EGX46_08575	COG2226	methyltransferase
EGX46_08580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGX46_08595	COG4628	conserved protein (DUF2132)
EGX46_08600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGX46_08605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX46_08615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EGX46_08620	COG0314	molybdopterin synthase activity
EGX46_08625	COG0670	Belongs to the BI1 family
EGX46_08630	COG1943	Transposase
EGX46_08650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX46_08655	COG0583	DNA-binding transcription factor activity
EGX46_08665	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGX46_08670	COG2211	Major facilitator Superfamily
EGX46_08675	COG1943	Transposase
EGX46_08700	COG1902	pentaerythritol trinitrate reductase activity
EGX46_08720	COG0842	Transport permease protein
EGX46_08725	COG0842	Transport permease protein
EGX46_08730	COG1131	(ABC) transporter
EGX46_08740	COG1309	transcriptional regulator
EGX46_08745	COG0513	Belongs to the DEAD box helicase family
EGX46_08780	COG3328	transposase activity
EGX46_08835	COG1132	(ABC) transporter
EGX46_08845	COG2207	Transcriptional regulator
EGX46_08885	COG1113	amino acid transport
EGX46_08905	COG1278	Cold shock
EGX46_08915	COG2226	methyltransferase
EGX46_08925	COG5001	Diguanylate cyclase
EGX46_08925	COG5002	protein histidine kinase activity
EGX46_08925	COG3447	MASE1 domain protein
EGX46_08945	COG3716	PTS system mannose fructose sorbose family IID component
EGX46_08950	COG3715	PTS system
EGX46_08955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_08955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_08960	COG1253	flavin adenine dinucleotide binding
EGX46_08970	COG1846	Transcriptional regulator
EGX46_08985	COG1012	belongs to the aldehyde dehydrogenase family
EGX46_08990	COG3384	dioxygenase
EGX46_09000	COG3971	2-oxopent-4-enoate hydratase activity
EGX46_09015	COG2368	4-hydroxyphenylacetate
EGX46_09025	COG1760	l-serine dehydratase
EGX46_09050	COG0513	Belongs to the DEAD box helicase family
EGX46_09055	COG3141	response to X-ray
EGX46_09070	COG1770	oligopeptidase
EGX46_09095	COG1528	Iron-storage protein
EGX46_09100	COG2372	response to copper ion
EGX46_09135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX46_09140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX46_09155	COG1943	Transposase
EGX46_09165	COG3418	PFAM FlgN family protein
EGX46_09170	COG2747	anti-sigma28 factor FlgM
EGX46_09180	COG1815	bacterial-type flagellum-dependent cell motility
EGX46_09185	COG1558	bacterial-type flagellum-dependent cell motility
EGX46_09190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGX46_09195	COG1749	Flagellar hook protein flgE
EGX46_09205	COG4786	Flagellar basal body rod
EGX46_09225	COG1256	bacterial-type flagellum assembly
EGX46_09235	COG2390	Transcriptional regulator
EGX46_09240	COG3347	Dehydrogenase
EGX46_09240	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_09245	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_09255	COG1129	ABC transporter
EGX46_09260	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_09265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_09285	COG1987	bacterial-type flagellum assembly
EGX46_09310	COG1580	Controls the rotational direction of flagella during chemotaxis
EGX46_09320	COG2882	bacterial-type flagellum organization
EGX46_09325	COG1157	protein secretion by the type III secretion system
EGX46_09335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGX46_09345	COG1677	Flagellar hook-basal body complex protein FliE
EGX46_09365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EGX46_09370	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EGX46_09375	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EGX46_09410	COG1191	sigma factor activity
EGX46_09420	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EGX46_09460	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX46_09460	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX46_09460	COG0506	proline dehydrogenase activity
EGX46_09485	COG2837	iron assimilation
EGX46_09500	COG1113	amino acid transport
EGX46_09525	COG3136	membrane protein required for alginate biosynthesis
EGX46_09535	COG2197	response regulator
EGX46_09690	COG0673	inositol 2-dehydrogenase activity
EGX46_09700	COG1175	transmembrane transport
EGX46_09705	COG0395	ABC-type sugar transport system, permease component
EGX46_09780	COG4771	TonB-dependent receptor
EGX46_09785	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGX46_09805	COG3433	isochorismatase activity
EGX46_09805	COG2226	methyltransferase
EGX46_09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX46_09820	COG1132	(ABC) transporter
EGX46_09825	COG2814	Major facilitator Superfamily
EGX46_09830	COG1169	isochorismate synthase
EGX46_09835	COG0582	viral genome integration into host DNA
EGX46_09845	COG3121	Chaperone
EGX46_09855	COG3188	usher protein
EGX46_09870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_09870	COG2205	protein histidine kinase activity
EGX46_09880	COG0427	acetyl-CoA hydrolase
EGX46_09885	COG2030	dehydratase
EGX46_09950	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX46_09955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX46_09965	COG1349	DNA-binding transcription factor activity
EGX46_09975	COG2066	Belongs to the glutaminase family
EGX46_09985	COG0672	)-iron permease
EGX46_10000	COG0577	efflux transmembrane transporter activity
EGX46_10000	COG1136	(ABC) transporter
EGX46_10010	COG1136	(ABC) transporter
EGX46_10010	COG0577	efflux transmembrane transporter activity
EGX46_10030	COG0006	proline dipeptidase activity
EGX46_10035	COG0457	Tetratricopeptide repeat
EGX46_10040	COG0726	polysaccharide deacetylase
EGX46_10040	COG1649	PFAM Uncharacterised BCR, COG1649
EGX46_10045	COG1215	transferase activity, transferring glycosyl groups
EGX46_10050	COG3658	cytochrome
EGX46_10065	COG1702	phosphate starvation-inducible protein PhoH
EGX46_10070	COG0387	Pfam Sodium calcium exchanger
EGX46_10075	COG3850	Histidine kinase
EGX46_10085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX46_10150	COG0402	S-adenosylhomocysteine deaminase activity
EGX46_10170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_10215	COG3328	transposase activity
EGX46_10240	COG0500	methyltransferase
EGX46_10280	COG5002	protein histidine kinase activity
EGX46_10335	COG0012	GTP binding
EGX46_10350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX46_10375	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX46_10380	COG3094	Invasion gene expression up-regulator, SirB
EGX46_10385	COG2912	Transglutaminase-like superfamily
EGX46_10395	COG0659	secondary active sulfate transmembrane transporter activity
EGX46_10410	COG0659	secondary active sulfate transmembrane transporter activity
EGX46_10435	COG3833	ABC-type maltose transport systems, permease component
EGX46_10440	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX46_10450	COG1943	Transposase
EGX46_10460	COG0584	glycerophosphoryl diester phosphodiesterase
EGX46_10465	COG1940	carbohydrate kinase activity
EGX46_10480	COG3381	protein complex oligomerization
EGX46_10495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX46_10505	COG0728	peptidoglycan biosynthetic process
EGX46_10525	COG3102	Protein conserved in bacteria
EGX46_10545	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EGX46_10550	COG1801	Protein of unknown function DUF72
EGX46_10560	COG0494	nUDIX hydrolase
EGX46_10580	COG1943	Transposase
EGX46_10600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX46_10610	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EGX46_10615	COG0739	heme binding
EGX46_10620	COG1560	Kdo2-lipid A biosynthetic process
EGX46_10630	COG0469	pyruvate kinase activity
EGX46_10635	COG1737	Transcriptional regulator
EGX46_10640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX46_10650	COG0800	Aldolase
EGX46_10665	COG0251	oxidation-reduction process
EGX46_10670	COG1199	ATP-dependent helicase activity
EGX46_10680	COG3065	identical protein binding
EGX46_10690	COG0318	PFAM AMP-dependent synthetase and ligase
EGX46_10695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EGX46_10700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGX46_10705	COG2894	cell division
EGX46_10725	COG2951	lytic endotransglycosylase activity
EGX46_10730	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX46_10740	COG0582	viral genome integration into host DNA
EGX46_10820	COG1943	Transposase
EGX46_10905	COG3328	transposase activity
EGX46_10915	COG1104	cysteine desulfurase activity
EGX46_10950	COG2719	SpoVR family
EGX46_10960	COG2814	Major facilitator Superfamily
EGX46_10970	COG0583	DNA-binding transcription factor activity
EGX46_10985	COG2766	serine protein kinase
EGX46_10995	COG3713	MltA-interacting MipA family protein
EGX46_11015	COG3139	Protein of unknown function (DUF1315)
EGX46_11020	COG1335	isochorismatase
EGX46_11025	COG0252	asparaginase activity
EGX46_11030	COG0616	signal peptide processing
EGX46_11035	COG0778	Nitroreductase
EGX46_11040	COG0709	Synthesizes selenophosphate from selenide and ATP
EGX46_11045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX46_11055	COG0494	nUDIX hydrolase
EGX46_11060	COG0708	Exodeoxyribonuclease III
EGX46_11065	COG0583	DNA-binding transcription factor activity
EGX46_11085	COG3328	transposase activity
EGX46_11090	COG0788	formyltetrahydrofolate deformylase activity
EGX46_11100	COG0745	RESPONSE REGULATOR receiver
EGX46_11115	COG1435	thymidine kinase activity
EGX46_11135	COG1454	alcohol dehydrogenase
EGX46_11135	COG1012	belongs to the aldehyde dehydrogenase family
EGX46_11145	COG2095	MarC family integral membrane protein
EGX46_11155	COG0601	transmembrane transport
EGX46_11160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_11165	COG0444	Belongs to the ABC transporter superfamily
EGX46_11170	COG4608	Belongs to the ABC transporter superfamily
EGX46_11215	COG2350	Protein conserved in bacteria
EGX46_11220	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EGX46_11225	COG3328	transposase activity
EGX46_11230	COG1607	acyl-coa hydrolase
EGX46_11265	COG3047	cAMP biosynthetic process
EGX46_11285	COG0134	indole-3-glycerol-phosphate synthase activity
EGX46_11285	COG0135	phosphoribosylanthranilate isomerase activity
EGX46_11295	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX46_11320	COG0009	L-threonylcarbamoyladenylate synthase
EGX46_11325	COG1187	pseudouridine synthase activity
EGX46_11335	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_11340	COG0616	signal peptide processing
EGX46_11355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX46_11360	COG0583	DNA-binding transcription factor activity
EGX46_11370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX46_11375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX46_11380	COG0671	phosphoesterase, PA-phosphatase related
EGX46_11385	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EGX46_11390	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGX46_11405	COG0023	Translation Initiation Factor
EGX46_11425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX46_11430	COG2879	small protein
EGX46_11435	COG1966	Carbon starvation protein
EGX46_11445	COG2271	Major facilitator Superfamily
EGX46_11450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_11455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX46_11465	COG4659	FMN binding
EGX46_11470	COG4658	electron transport chain
EGX46_11475	COG3708	Transcriptional regulator
EGX46_11475	COG2207	Transcriptional regulator
EGX46_11510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_11515	COG2274	protein secretion by the type I secretion system
EGX46_11530	COG1879	ABC-type sugar transport system periplasmic component
EGX46_11540	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_11550	COG0673	inositol 2-dehydrogenase activity
EGX46_11555	COG0385	Bile acid
EGX46_11565	COG5339	Protein conserved in bacteria
EGX46_11575	COG0114	fumarate hydratase activity
EGX46_11585	COG2814	Major facilitator Superfamily
EGX46_11590	COG0583	DNA-binding transcription factor activity
EGX46_11595	COG1940	carbohydrate kinase activity
EGX46_11600	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGX46_11620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX46_11645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX46_11650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX46_11680	COG0028	Belongs to the TPP enzyme family
EGX46_11685	COG0440	acetolactate synthase activity
EGX46_11690	COG1011	Hydrolase
EGX46_11710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX46_11715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX46_11720	COG0589	response to stress
EGX46_11725	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EGX46_11730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EGX46_11745	COG0531	amino acid
EGX46_11755	COG0745	RESPONSE REGULATOR receiver
EGX46_11760	COG2205	protein histidine kinase activity
EGX46_11765	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EGX46_11770	COG1943	Transposase
EGX46_11800	COG3038	cytochrome b561
EGX46_11815	COG3591	Belongs to the peptidase S1B family
EGX46_11860	COG2390	Transcriptional regulator
EGX46_11865	COG0246	Mannitol dehydrogenase
EGX46_11870	COG3784	Protein of unknown function (DUF1318)
EGX46_11880	COG2911	Protein conserved in bacteria
EGX46_11885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX46_11890	COG3187	Heat shock protein
EGX46_11895	COG3042	response to heat
EGX46_11900	COG1285	pathogenesis
EGX46_11910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX46_11910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGX46_11910	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGX46_11910	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGX46_11920	COG0657	acetylesterase activity
EGX46_11920	COG2755	lipolytic protein G-D-S-L family
EGX46_11940	COG4166	transmembrane transport
EGX46_11945	COG2866	Carboxypeptidase
EGX46_11950	COG4948	Mandelate Racemase Muconate Lactonizing
EGX46_11955	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGX46_11960	COG1943	Transposase
EGX46_11985	COG3106	COG3106 Predicted ATPase
EGX46_11995	COG1983	PspC domain protein
EGX46_12005	COG1842	Phage shock protein A
EGX46_12010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EGX46_12015	COG1943	Transposase
EGX46_12030	COG4166	transmembrane transport
EGX46_12035	COG4168	peptide transport system, permease
EGX46_12040	COG4171	peptide transport system, permease
EGX46_12050	COG4172	Belongs to the ABC transporter superfamily
EGX46_12055	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX46_12055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX46_12060	COG3104	oligopeptide transport
EGX46_12095	COG3895	Periplasmic Protein
EGX46_12105	COG3133	Outer membrane lipoprotein
EGX46_12120	COG4989	oxidoreductase activity
EGX46_12125	COG3313	Fe-S protein
EGX46_12130	COG2194	sulfuric ester hydrolase activity
EGX46_12135	COG1309	transcriptional regulator
EGX46_12140	COG1902	pentaerythritol trinitrate reductase activity
EGX46_12150	COG0346	lactoylglutathione lyase activity
EGX46_12155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX46_12165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGX46_12175	COG0791	NLP P60 protein
EGX46_12180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX46_12195	COG0583	DNA-binding transcription factor activity
EGX46_12200	COG2814	Major facilitator Superfamily
EGX46_12205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGX46_12210	COG0307	riboflavin synthase, alpha
EGX46_12240	COG4238	major outer membrane lipoprotein
EGX46_12245	COG1943	Transposase
EGX46_12265	COG1376	ErfK ybiS ycfS ynhG family protein
EGX46_12265	COG1388	LysM domain
EGX46_12280	COG0719	Fe-S assembly protein
EGX46_12285	COG0396	ATPase activity
EGX46_12290	COG0719	Fe-S assembly protein
EGX46_12295	COG0316	Belongs to the HesB IscA family
EGX46_12305	COG2050	protein possibly involved in aromatic compounds catabolism
EGX46_12310	COG0247	lactate metabolic process
EGX46_12310	COG0277	FAD linked oxidase domain protein
EGX46_12315	COG0628	permease
EGX46_12325	COG0574	Belongs to the PEP-utilizing enzyme family
EGX46_12325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX46_12355	COG0791	NLP P60 protein
EGX46_12400	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EGX46_12405	COG0386	Belongs to the glutathione peroxidase family
EGX46_12420	COG0776	regulation of translation
EGX46_12425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX46_12425	COG0072	phenylalanine-tRNA ligase activity
EGX46_12460	COG4249	Peptidase C14 caspase catalytic subunit p20
EGX46_12485	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX46_12490	COG1121	(ABC) transporter
EGX46_12495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX46_12500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX46_12520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_12525	COG3328	transposase activity
EGX46_12530	COG1917	Cupin 2, conserved barrel domain protein
EGX46_12540	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_12570	COG1175	transmembrane transport
EGX46_12575	COG0395	ABC-type sugar transport system, permease component
EGX46_12580	COG3842	ATPase activity
EGX46_12585	COG1653	transport
EGX46_12590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX46_12595	COG1988	membrane-bound metal-dependent
EGX46_12605	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX46_12615	COG0823	Involved in the tonB-independent uptake of proteins
EGX46_12620	COG2814	Major facilitator Superfamily
EGX46_12625	COG3121	Chaperone
EGX46_12640	COG3121	Chaperone
EGX46_12645	COG3539	Fimbrial protein
EGX46_12660	COG0793	Belongs to the peptidase S41A family
EGX46_12670	COG1956	GAF domain-containing protein
EGX46_12675	COG2995	paraquat-inducible protein a
EGX46_12680	COG3008	intermembrane lipid transfer
EGX46_12700	COG3121	Chaperone
EGX46_12760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX46_12770	COG5295	Hep Hag repeat protein
EGX46_12780	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX46_12790	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EGX46_12795	COG0745	RESPONSE REGULATOR receiver
EGX46_12805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGX46_12810	COG0840	transmembrane signaling receptor activity
EGX46_12815	COG0840	transmembrane signaling receptor activity
EGX46_12835	COG2964	Protein conserved in bacteria
EGX46_12845	COG0251	oxidation-reduction process
EGX46_12850	COG2271	Major facilitator Superfamily
EGX46_12855	COG0835	chemotaxis
EGX46_12860	COG0643	Histidine kinase
EGX46_12860	COG2198	Histidine kinase
EGX46_12865	COG1360	Flagellar Motor Protein
EGX46_12890	COG1285	pathogenesis
EGX46_12905	COG1278	Cold shock
EGX46_12935	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_12935	COG3321	synthase
EGX46_12935	COG0604	alcohol dehydrogenase
EGX46_12945	COG1522	sequence-specific DNA binding
EGX46_12965	COG1733	regulation of RNA biosynthetic process
EGX46_12970	COG0702	epimerase
EGX46_12975	COG0840	transmembrane signaling receptor activity
EGX46_12990	COG0538	isocitrate dehydrogenase activity
EGX46_13015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX46_13025	COG0745	RESPONSE REGULATOR receiver
EGX46_13035	COG2850	peptidyl-arginine hydroxylation
EGX46_13050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGX46_13065	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX46_13075	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX46_13080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX46_13085	COG3134	Outer membrane lipoprotein
EGX46_13095	COG3328	transposase activity
EGX46_13110	COG1252	NADH dehydrogenase
EGX46_13120	COG1472	Belongs to the glycosyl hydrolase 3 family
EGX46_13135	COG5633	Lipoprotein
EGX46_13140	COG0537	adenosine 5'-monophosphoramidase activity
EGX46_13145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX46_13160	COG1943	Transposase
EGX46_13170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_13170	COG1263	PTS System
EGX46_13175	COG0084	hydrolase, TatD family'
EGX46_13180	COG0470	DNA polymerase III
EGX46_13190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGX46_13195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX46_13200	COG1943	Transposase
EGX46_13205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_13215	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_13235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGX46_13240	COG1399	metal-binding, possibly nucleic acid-binding protein
EGX46_13250	COG1943	Transposase
EGX46_13255	COG0564	pseudouridine synthase activity
EGX46_13265	COG1530	ribonuclease E activity
EGX46_13280	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EGX46_13305	COG3328	transposase activity
EGX46_13320	COG3328	transposase activity
EGX46_13325	COG2197	response regulator
EGX46_13335	COG0628	permease
EGX46_13360	COG3916	Acyl-homoserine-lactone synthase
EGX46_13365	COG2771	luxR family
EGX46_13370	COG0583	DNA-binding transcription factor activity
EGX46_13380	COG0477	Major facilitator Superfamily
EGX46_13390	COG0667	Aldo Keto reductase
EGX46_13415	COG1203	CRISPR-associated helicase, Cas3
EGX46_13420	COG1518	maintenance of DNA repeat elements
EGX46_13425	COG0668	transmembrane transport
EGX46_13455	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EGX46_13460	COG0395	ABC-type sugar transport system, permease component
EGX46_13475	COG1609	Transcriptional regulator
EGX46_13485	COG3842	ATPase activity
EGX46_13495	COG3210	domain, Protein
EGX46_13500	COG3210	domain, Protein
EGX46_13525	COG3210	domain, Protein
EGX46_13545	COG3210	domain, Protein
EGX46_13550	COG2831	hemolysin activation secretion protein
EGX46_13555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_13560	COG4638	Rieske (2fe-2S)
EGX46_13565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX46_13575	COG0473	3-isopropylmalate dehydrogenase activity
EGX46_13580	COG0583	DNA-binding transcription factor activity
EGX46_13585	COG1609	Transcriptional regulator
EGX46_13590	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_13595	COG1129	ABC transporter
EGX46_13600	COG1879	ABC-type sugar transport system periplasmic component
EGX46_13635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_13640	COG0765	amino acid transport
EGX46_13645	COG1126	abc transporter atp-binding protein
EGX46_13695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX46_13710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGX46_13725	COG1169	isochorismate synthase
EGX46_13735	COG4575	ribosome binding
EGX46_13750	COG0129	dihydroxy-acid dehydratase activity
EGX46_13765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX46_13770	COG1609	Transcriptional regulator
EGX46_13780	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_13785	COG3265	gluconokinase activity
EGX46_13790	COG2731	YhcH YjgK YiaL family protein
EGX46_13805	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX46_13810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX46_13820	COG0839	Belongs to the complex I subunit 6 family
EGX46_13835	COG1034	ATP synthesis coupled electron transport
EGX46_13845	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EGX46_13855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX46_13865	COG0583	DNA-binding transcription factor activity
EGX46_13870	COG0436	Aminotransferase
EGX46_13885	COG0471	metal ion transport
EGX46_13885	COG0490	domain, Protein
EGX46_13890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_13910	COG0857	belongs to the CobB CobQ family
EGX46_13910	COG0280	phosphate acetyltransferase
EGX46_13915	COG1609	Transcriptional regulator
EGX46_13930	COG3037	sugar-specific permease SgaT UlaA
EGX46_13935	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGX46_13950	COG1090	epimerase
EGX46_13955	COG4598	ABC transporter
EGX46_13960	COG4160	amino acid transport
EGX46_13965	COG4215	(ABC) transporter
EGX46_13970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_13985	COG0163	prenyltransferase activity
EGX46_13990	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGX46_13995	COG1286	toxin biosynthetic process
EGX46_14000	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EGX46_14005	COG0285	dihydrofolate synthase activity
EGX46_14015	COG0586	Pfam SNARE associated Golgi protein
EGX46_14025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX46_14040	COG0697	spore germination
EGX46_14055	COG1794	racemase activity, acting on amino acids and derivatives
EGX46_14060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_14075	COG3101	peptidyl-lysine hydroxylation
EGX46_14080	COG0730	response to heat
EGX46_14095	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX46_14105	COG2062	phosphohistidine phosphatase, SixA
EGX46_14120	COG3691	Protein conserved in bacteria
EGX46_14135	COG4235	cytochrome complex assembly
EGX46_14135	COG3088	subunit of a heme lyase
EGX46_14140	COG3088	subunit of a heme lyase
EGX46_14140	COG4235	cytochrome complex assembly
EGX46_14145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX46_14150	COG1138	Cytochrome C-type biogenesis protein
EGX46_14160	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX46_14165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX46_14170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX46_14190	COG1704	LemA family
EGX46_14200	COG2824	Alkylphosphonate utilization operon protein PhnA
EGX46_14230	COG3501	Rhs element vgr protein
EGX46_14290	COG3188	usher protein
EGX46_14295	COG3328	transposase activity
EGX46_14305	COG3188	usher protein
EGX46_14310	COG3121	Chaperone
EGX46_14370	COG2951	lytic endotransglycosylase activity
EGX46_14405	COG0243	molybdopterin cofactor binding
EGX46_14410	COG0437	4 iron, 4 sulfur cluster binding
EGX46_14415	COG3302	dmso reductase anchor subunit
EGX46_14430	COG3381	protein complex oligomerization
EGX46_14460	COG3038	cytochrome b561
EGX46_14465	COG0436	Aminotransferase
EGX46_14490	COG0667	Aldo Keto reductase
EGX46_14505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX46_14545	COG1943	Transposase
EGX46_14570	COG3530	Putative quorum-sensing-regulated virulence factor
EGX46_14585	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EGX46_14590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX46_14595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_14605	COG2190	(PTS) system
EGX46_14610	COG1943	Transposase
EGX46_14620	COG2205	protein histidine kinase activity
EGX46_14625	COG0745	RESPONSE REGULATOR receiver
EGX46_14630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_14645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX46_14655	COG0006	proline dipeptidase activity
EGX46_14665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGX46_14675	COG3850	Histidine kinase
EGX46_14675	COG5002	protein histidine kinase activity
EGX46_14680	COG0745	RESPONSE REGULATOR receiver
EGX46_14695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGX46_14700	COG4208	sulfate ABC transporter
EGX46_14705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGX46_14710	COG4150	thiosulfate binding
EGX46_14720	COG1737	Transcriptional regulator
EGX46_14730	COG2731	YhcH YjgK YiaL family protein
EGX46_14750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX46_14755	COG2837	iron assimilation
EGX46_14765	COG3111	PFAM Bacterial OB fold (BOF) protein
EGX46_14830	COG3005	denitrification pathway
EGX46_14835	COG3043	anaerobic respiration
EGX46_14845	COG3062	negative regulation of establishment of protein localization
EGX46_14850	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_14850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_14855	COG2197	response regulator
EGX46_14865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_14875	COG1988	membrane-bound metal-dependent
EGX46_14880	COG0641	radical SAM
EGX46_14885	COG3119	arylsulfatase activity
EGX46_14895	COG3842	ATPase activity
EGX46_14900	COG1175	transmembrane transport
EGX46_14905	COG1840	ABC-type Fe3 transport system, periplasmic component
EGX46_14915	COG1393	Belongs to the ArsC family
EGX46_14925	COG1876	peptidase activity
EGX46_14950	COG2321	neutral zinc metallopeptidase
EGX46_14965	COG1943	Transposase
EGX46_14970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EGX46_14980	COG2716	regulation of RNA biosynthetic process
EGX46_14985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX46_15000	COG0628	permease
EGX46_15005	COG4783	chaperone-mediated protein folding
EGX46_15010	COG1393	Belongs to the ArsC family
EGX46_15020	COG1943	Transposase
EGX46_15035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGX46_15040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX46_15055	COG0581	inorganic phosphate transmembrane transporter activity
EGX46_15065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGX46_15070	COG0248	Ppx GppA phosphatase
EGX46_15080	COG2239	Acts as a magnesium transporter
EGX46_15085	COG0443	Heat shock 70 kDa protein
EGX46_15105	COG1177	transmembrane transport
EGX46_15110	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX46_15120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGX46_15130	COG3842	ATPase activity
EGX46_15160	COG0745	RESPONSE REGULATOR receiver
EGX46_15165	COG3422	double-strand break repair
EGX46_15195	COG0351	phosphomethylpyrimidine kinase
EGX46_15210	COG3328	transposase activity
EGX46_15260	COG0516	GMP reductase activity
EGX46_15260	COG0517	IMP dehydrogenase activity
EGX46_15275	COG1645	bacterial-type flagellum-dependent swarming motility
EGX46_15290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX46_15295	COG2976	Protein conserved in bacteria
EGX46_15340	COG3468	outer membrane autotransporter barrel domain protein
EGX46_15345	COG3468	outer membrane autotransporter barrel domain protein
EGX46_15370	COG2975	iron-sulfur cluster assembly
EGX46_15375	COG0633	Ferredoxin
EGX46_15380	COG0443	Heat shock 70 kDa protein
EGX46_15400	COG0822	iron-sulfur transferase activity
EGX46_15405	COG1104	cysteine desulfurase activity
EGX46_15420	COG0483	inositol monophosphate 1-phosphatase activity
EGX46_15425	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX46_15430	COG3683	transport system, periplasmic component
EGX46_15435	COG3711	transcriptional antiterminator
EGX46_15440	COG2814	Major facilitator Superfamily
EGX46_15460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_15460	COG1017	nitric oxide dioxygenase activity
EGX46_15470	COG0347	Belongs to the P(II) protein family
EGX46_15475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX46_15475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX46_15480	COG2204	response regulator
EGX46_15485	COG3170	Tfp pilus assembly protein FimV
EGX46_15490	COG2205	protein histidine kinase activity
EGX46_15500	COG1943	Transposase
EGX46_15535	COG0590	tRNA wobble adenosine to inosine editing
EGX46_15540	COG0560	Phosphoserine phosphatase
EGX46_15550	COG1737	Transcriptional regulator
EGX46_15555	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_15560	COG1943	Transposase
EGX46_15570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGX46_15590	COG2113	Glycine betaine
EGX46_15595	COG4176	ABC-type proline glycine betaine transport system permease component
EGX46_15600	COG4175	Glycine betaine
EGX46_15605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX46_15635	COG3328	transposase activity
EGX46_15660	COG1278	Cold shock
EGX46_15665	COG0747	negative chemotaxis
EGX46_15675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_15680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EGX46_15685	COG1124	(ABC) transporter
EGX46_15715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGX46_15725	COG4413	Urea transporter
EGX46_15730	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX46_15745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX46_15750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX46_15755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX46_15765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX46_15770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX46_15775	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGX46_15780	COG1917	Cupin 2, conserved barrel domain protein
EGX46_15780	COG2169	Transcriptional regulator
EGX46_15805	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EGX46_15810	COG0033	Phosphoglucomutase
EGX46_15825	COG0745	RESPONSE REGULATOR receiver
EGX46_15830	COG2205	protein histidine kinase activity
EGX46_15870	COG3272	Protein of unknown function (DUF1722)
EGX46_15880	COG5212	phosphodiesterase
EGX46_15885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGX46_15900	COG1984	allophanate hydrolase subunit 2
EGX46_15950	COG0513	Belongs to the DEAD box helicase family
EGX46_15960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGX46_15970	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EGX46_15975	COG3026	antisigma factor binding
EGX46_15980	COG3086	response to oxidative stress
EGX46_15995	COG0681	Belongs to the peptidase S26 family
EGX46_16035	COG0582	viral genome integration into host DNA
EGX46_16045	COG0596	Alpha beta hydrolase
EGX46_16065	COG0735	belongs to the Fur family
EGX46_16090	COG1943	Transposase
EGX46_16100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_16100	COG1263	PTS System
EGX46_16100	COG2190	(PTS) system
EGX46_16110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX46_16115	COG1940	carbohydrate kinase activity
EGX46_16115	COG1846	Transcriptional regulator
EGX46_16120	COG0647	UMP catabolic process
EGX46_16125	COG0367	asparagine synthase
EGX46_16165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX46_16175	COG1702	phosphate starvation-inducible protein PhoH
EGX46_16185	COG4535	Mg2 and Co2 transporter CorC
EGX46_16190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGX46_16200	COG0765	amino acid transport
EGX46_16205	COG0765	amino acid transport
EGX46_16210	COG1126	abc transporter atp-binding protein
EGX46_16215	COG2888	peptidyl-tyrosine sulfation
EGX46_16230	COG1466	dna polymerase III delta subunit
EGX46_16240	COG0799	negative regulation of ribosome biogenesis
EGX46_16250	COG0768	penicillin binding
EGX46_16255	COG0772	Belongs to the SEDS family
EGX46_16260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX46_16280	COG1686	Belongs to the peptidase S11 family
EGX46_16305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX46_16310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX46_16315	COG1278	Cold shock
EGX46_16320	COG1278	Cold shock
EGX46_16325	COG2197	response regulator
EGX46_16350	COG5265	(ABC) transporter
EGX46_16360	COG3718	enzyme involved in inositol metabolism
EGX46_16375	COG0673	inositol 2-dehydrogenase activity
EGX46_16380	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_16385	COG1129	ABC transporter
EGX46_16390	COG1879	ABC-type sugar transport system periplasmic component
EGX46_16400	COG3962	Belongs to the TPP enzyme family
EGX46_16425	COG2373	Large extracellular alpha-helical protein
EGX46_16430	COG4953	penicillin-binding protein 1C
EGX46_16435	COG3328	transposase activity
EGX46_16445	COG3423	Transcriptional regulator
EGX46_16500	COG3328	transposase activity
EGX46_16525	COG0656	L-ascorbic acid biosynthetic process
EGX46_16530	COG0667	Aldo Keto reductase
EGX46_16570	COG0671	phosphoesterase, PA-phosphatase related
EGX46_16570	COG2453	phosphatase
EGX46_16575	COG2267	carboxylic ester hydrolase activity
EGX46_16585	COG4589	Belongs to the CDS family
EGX46_16590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX46_16605	COG0582	viral genome integration into host DNA
EGX46_16640	COG2501	S4 domain
EGX46_16645	COG1943	Transposase
EGX46_16660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX46_16675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGX46_16680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX46_16685	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGX46_16690	COG4181	ATPase activity
EGX46_16695	COG2755	lipolytic protein G-D-S-L family
EGX46_16700	COG0300	oxidoreductase activity
EGX46_16705	COG3118	belongs to the thioredoxin family
EGX46_16710	COG0330	HflC and HflK could
EGX46_16715	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGX46_16720	COG0789	Transcriptional regulator
EGX46_16725	COG2217	Heavy metal translocating P-type atpase
EGX46_16730	COG3735	TraB family
EGX46_16735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX46_16750	COG2223	nitrite transmembrane transporter activity
EGX46_16755	COG4651	solute:proton antiporter activity
EGX46_16755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX46_16760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_16765	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX46_16785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_16835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_16860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_16860	COG0543	2 iron, 2 sulfur cluster binding
EGX46_16890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX46_16900	COG2832	Protein of unknown function (DUF454)
EGX46_16940	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGX46_16945	COG1309	transcriptional regulator
EGX46_16950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_16955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_16965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX46_16990	COG3695	enzyme binding
EGX46_16995	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EGX46_17000	COG1946	Acyl-CoA thioesterase
EGX46_17005	COG0004	ammonium transporteR
EGX46_17010	COG0347	Belongs to the P(II) protein family
EGX46_17015	COG1132	(ABC) transporter
EGX46_17020	COG1132	(ABC) transporter
EGX46_17025	COG1522	sequence-specific DNA binding
EGX46_17040	COG4533	DNA binding
EGX46_17050	COG0824	Thioesterase
EGX46_17055	COG1555	photosystem II stabilization
EGX46_17060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX46_17065	COG0776	regulation of translation
EGX46_17070	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGX46_17095	COG0271	Belongs to the BolA IbaG family
EGX46_17100	COG3056	Lipoprotein
EGX46_17105	COG2223	nitrite transmembrane transporter activity
EGX46_17115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX46_17120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX46_17125	COG1845	cytochrome c oxidase, subunit III
EGX46_17130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX46_17140	COG2814	Major facilitator Superfamily
EGX46_17155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGX46_17160	COG0693	protein deglycase activity
EGX46_17175	COG0142	geranyltranstransferase activity
EGX46_17185	COG1943	Transposase
EGX46_17190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGX46_17195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGX46_17210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX46_17210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX46_17235	COG1943	Transposase
EGX46_17240	COG1943	Transposase
EGX46_17245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX46_17250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX46_17255	COG1862	Preprotein translocase
EGX46_17265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGX46_17270	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EGX46_17275	COG0450	alkyl hydroperoxide reductase
EGX46_17300	COG0366	Alpha amylase catalytic
EGX46_17310	COG1114	Component of the transport system for branched-chain amino acids
EGX46_17320	COG5002	protein histidine kinase activity
EGX46_17325	COG0745	RESPONSE REGULATOR receiver
EGX46_17330	COG0420	3'-5' exonuclease activity
EGX46_17335	COG0419	ATPase involved in DNA repair
EGX46_17360	COG1940	carbohydrate kinase activity
EGX46_17390	COG2226	methyltransferase
EGX46_17440	COG0583	DNA-binding transcription factor activity
EGX46_17445	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX46_17465	COG1477	protein flavinylation
EGX46_17485	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX46_17490	COG1805	sodium ion transport
EGX46_17495	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX46_17505	COG3034	peptidoglycan biosynthetic process
EGX46_17510	COG0121	glutamine amidotransferase
EGX46_17520	COG1960	acyl-CoA dehydrogenase activity
EGX46_17530	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
EGX46_17555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX46_17575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX46_17625	COG2814	Major facilitator Superfamily
EGX46_17630	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX46_17640	COG1846	Transcriptional regulator
EGX46_17645	COG1566	PFAM secretion protein HlyD family protein
EGX46_17650	COG2814	Major facilitator Superfamily
EGX46_17655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX46_17660	COG3118	belongs to the thioredoxin family
EGX46_17670	COG0045	succinate-CoA ligase (ADP-forming) activity
EGX46_17670	COG1042	CoA-binding domain protein
EGX46_17670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX46_17675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX46_17680	COG5544	Lipoprotein
EGX46_17720	COG0542	response to heat
EGX46_17730	COG0564	pseudouridine synthase activity
EGX46_17740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX46_17745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGX46_17750	COG1943	Transposase
EGX46_17755	COG1943	Transposase
EGX46_17760	COG1605	Chorismate mutase
EGX46_17760	COG0077	Prephenate dehydratase
EGX46_17790	COG0529	Catalyzes the synthesis of activated sulfate
EGX46_17805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGX46_17830	COG1388	LysM domain
EGX46_17830	COG4942	peptidase
EGX46_17835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX46_17845	COG0698	ribose 5-phosphate isomerase
EGX46_17850	COG1063	alcohol dehydrogenase
EGX46_17855	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_17860	COG2376	Dihydroxyacetone kinase
EGX46_17875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX46_17895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_17900	COG1858	cytochrome C peroxidase
EGX46_17910	COG4771	TonB-dependent receptor
EGX46_17925	COG0024	Methionine aminopeptidase
EGX46_17935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX46_17935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX46_17940	COG1070	Carbohydrate kinase
EGX46_17945	COG3623	hexulose-6-phosphate isomerase
EGX46_17950	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_17955	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_17960	COG1129	ABC transporter
EGX46_17965	COG1943	Transposase
EGX46_17975	COG1349	DNA-binding transcription factor activity
EGX46_17980	COG0235	Class ii aldolase
EGX46_17985	COG0243	molybdopterin cofactor binding
EGX46_17990	COG0437	4 iron, 4 sulfur cluster binding
EGX46_17995	COG3302	dmso reductase anchor subunit
EGX46_18000	COG3381	protein complex oligomerization
EGX46_18005	COG3038	cytochrome b561
EGX46_18010	COG3783	Cytochrome b(562)
EGX46_18030	COG1129	ABC transporter
EGX46_18035	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_18040	COG3959	Transketolase, thiamine diphosphate binding domain
EGX46_18045	COG3958	Transketolase
EGX46_18050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX46_18090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGX46_18095	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EGX46_18130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_18135	COG1238	metal cluster binding
EGX46_18140	COG2918	glutathione biosynthetic process
EGX46_18150	COG1943	Transposase
EGX46_18155	COG4536	flavin adenine dinucleotide binding
EGX46_18160	COG4137	Cytochrome C assembly protein
EGX46_18165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX46_18190	COG1943	Transposase
EGX46_18195	COG3137	Salt-induced outer membrane protein
EGX46_18205	COG3279	Response regulator of the LytR AlgR family
EGX46_18210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX46_18215	COG0287	Prephenate dehydrogenase
EGX46_18215	COG1605	Chorismate mutase
EGX46_18275	COG0720	synthase
EGX46_18280	COG0602	queuosine metabolic process
EGX46_18300	COG3956	TIGRFAM MazG family protein
EGX46_18305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX46_18310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGX46_18320	COG4999	Histidine kinase
EGX46_18320	COG3850	Histidine kinase
EGX46_18320	COG3437	response regulator, receiver
EGX46_18320	COG2205	protein histidine kinase activity
EGX46_18325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX46_18345	COG2860	membrane
EGX46_18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_18370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX46_18375	COG1120	ATPase activity
EGX46_18380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX46_18385	COG1643	Atp-dependent helicase
EGX46_18390	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGX46_18405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGX46_18415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX46_18420	COG0617	tRNA 3'-terminal CCA addition
EGX46_18425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX46_18450	COG0842	Transport permease protein
EGX46_18455	COG1131	(ABC) transporter
EGX46_18460	COG0288	reversible hydration of carbon dioxide
EGX46_18465	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGX46_18470	COG2132	Multicopper oxidase
EGX46_18490	COG0697	spore germination
EGX46_18500	COG1049	propionate catabolic process, 2-methylcitrate cycle
EGX46_18510	COG1943	Transposase
EGX46_18515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX46_18520	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX46_18525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EGX46_18530	COG2186	Transcriptional regulator
EGX46_18540	COG1113	amino acid transport
EGX46_18545	COG3725	Membrane protein required for beta-lactamase induction
EGX46_18550	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX46_18560	COG4969	Belongs to the N-Me-Phe pilin family
EGX46_18565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX46_18570	COG1459	type II secretion system
EGX46_18585	COG0237	dephospho-CoA kinase activity
EGX46_18600	COG1943	Transposase
EGX46_18625	COG0582	viral genome integration into host DNA
EGX46_18635	COG0795	lipopolysaccharide-transporting ATPase activity
EGX46_18640	COG0795	lipopolysaccharide-transporting ATPase activity
EGX46_18650	COG2927	DNA polymerase III (CHI subunit)
EGX46_18655	COG0525	valine-tRNA ligase activity
EGX46_18665	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EGX46_18670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGX46_18675	COG2731	YhcH YjgK YiaL family protein
EGX46_18685	COG0601	transmembrane transport
EGX46_18690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_18695	COG0444	Belongs to the ABC transporter superfamily
EGX46_18700	COG4608	Belongs to the ABC transporter superfamily
EGX46_18715	COG2188	Transcriptional regulator
EGX46_18720	COG3624	Phosphonate C-P lyase system protein PhnG
EGX46_18725	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EGX46_18730	COG3626	phosphonate metabolism
EGX46_18735	COG3627	carbon phosphorus lyase activity
EGX46_18740	COG4107	phosphonate C-P lyase system protein PhnK
EGX46_18745	COG4778	phosphonate C-P lyase system protein PhnL
EGX46_18750	COG3454	Phosphonate metabolism
EGX46_18755	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EGX46_18760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGX46_18765	COG0702	epimerase
EGX46_18780	COG3842	ATPase activity
EGX46_18785	COG0395	ABC-type sugar transport system, permease component
EGX46_18795	COG1653	transport
EGX46_18815	COG3153	acetyltransferase
EGX46_18845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_18855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX46_18880	COG0513	Belongs to the DEAD box helicase family
EGX46_18910	COG2423	ornithine cyclodeaminase activity
EGX46_18915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX46_18925	COG5645	(Lipo)protein
EGX46_18945	COG3977	Valine--pyruvate aminotransferase
EGX46_18965	COG0366	Alpha amylase catalytic
EGX46_18985	COG2885	chlorophyll binding
EGX46_18995	COG2818	Glycosylase
EGX46_19015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_19015	COG2213	PTS system mannitol-specific
EGX46_19025	COG3722	fumarate hydratase activity
EGX46_19065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX46_19075	COG0243	molybdopterin cofactor binding
EGX46_19075	COG3383	formate dehydrogenase (NAD+) activity
EGX46_19080	COG3383	formate dehydrogenase (NAD+) activity
EGX46_19080	COG0243	molybdopterin cofactor binding
EGX46_19085	COG0437	4 iron, 4 sulfur cluster binding
EGX46_19090	COG2864	formate dehydrogenase
EGX46_19105	COG3276	selenocysteine insertion sequence binding
EGX46_19185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EGX46_19190	COG1191	sigma factor activity
EGX46_19215	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EGX46_19235	COG3710	Transcriptional regulator
EGX46_19255	COG1256	bacterial-type flagellum assembly
EGX46_19265	COG1706	bacterial-type flagellum-dependent cell motility
EGX46_19270	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EGX46_19275	COG4786	Flagellar basal body rod
EGX46_19280	COG4787	bacterial-type flagellum-dependent cell motility
EGX46_19285	COG1749	Flagellar hook protein flgE
EGX46_19290	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGX46_19295	COG1558	bacterial-type flagellum-dependent cell motility
EGX46_19300	COG1815	bacterial-type flagellum-dependent cell motility
EGX46_19305	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EGX46_19365	COG2204	response regulator
EGX46_19385	COG1987	bacterial-type flagellum assembly
EGX46_19390	COG1684	flagellar biosynthetic protein fliR
EGX46_19395	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX46_19415	COG4592	Periplasmic binding protein
EGX46_19435	COG1943	Transposase
EGX46_19450	COG4964	Belongs to the GSP D family
EGX46_19455	COG4964	Belongs to the GSP D family
EGX46_19510	COG0848	biopolymer transport protein
EGX46_19515	COG0811	peptide transport
EGX46_19520	COG0626	cystathionine gamma-synthase activity
EGX46_19530	COG2207	Transcriptional regulator
EGX46_19535	COG1979	alcohol dehydrogenase
EGX46_19545	COG0656	L-ascorbic acid biosynthetic process
EGX46_19560	COG2132	Multicopper oxidase
EGX46_19570	COG0204	Acyl-transferase
EGX46_19575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX46_19585	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX46_19590	COG0583	DNA-binding transcription factor activity
EGX46_19595	COG0187	DNA topoisomerase II activity
EGX46_19600	COG3150	esterase
EGX46_19610	COG3151	Protein conserved in bacteria
EGX46_19615	COG0494	nUDIX hydrolase
EGX46_19620	COG1538	Outer membrane efflux protein
EGX46_19635	COG0754	glutathionylspermidine amidase activity
EGX46_19640	COG3384	dioxygenase
EGX46_19660	COG0531	amino acid
EGX46_19675	COG3025	triphosphatase activity
EGX46_19680	COG4991	sh3 domain protein
EGX46_19695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGX46_19720	COG0358	DNA primase activity
EGX46_19725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX46_19815	COG0251	oxidation-reduction process
EGX46_19860	COG1289	transmembrane transporter activity
EGX46_19880	COG0395	ABC-type sugar transport system, permease component
EGX46_19890	COG1653	transport
EGX46_19895	COG1609	Transcriptional regulator
EGX46_19900	COG3459	Glycosyltransferase 36 associated
EGX46_19905	COG3842	ATPase activity
EGX46_19925	COG3210	domain, Protein
EGX46_19930	COG3210	domain, Protein
EGX46_19955	COG3210	domain, Protein
EGX46_19960	COG2831	hemolysin activation secretion protein
EGX46_19965	COG4245	von Willebrand factor, type A
EGX46_19980	COG4245	von Willebrand factor, type A
EGX46_20000	COG3247	response to pH
EGX46_20005	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX46_20005	COG1902	pentaerythritol trinitrate reductase activity
EGX46_20020	COG1451	nucleotide metabolic process
EGX46_20025	COG0673	inositol 2-dehydrogenase activity
EGX46_20040	COG1943	Transposase
EGX46_20050	COG2721	sulfolactate sulfo-lyase activity
EGX46_20065	COG2271	Major facilitator Superfamily
EGX46_20080	COG0586	Pfam SNARE associated Golgi protein
EGX46_20100	COG4575	ribosome binding
EGX46_20105	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EGX46_20115	COG2259	Doxx family
EGX46_20120	COG0435	Glutathione S-transferase
EGX46_20135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGX46_20150	COG0551	DNA topoisomerase type I activity
EGX46_20160	COG0758	DNA mediated transformation
EGX46_20180	COG0569	domain protein
EGX46_20190	COG3036	rescue of stalled ribosome
EGX46_20195	COG0789	Transcriptional regulator
EGX46_20210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGX46_20225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX46_20230	COG0201	protein transport
EGX46_20240	COG1841	ribosomal large subunit assembly
EGX46_20280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGX46_20285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGX46_20295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGX46_20310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGX46_20335	COG0051	transcription antitermination factor activity, RNA binding
EGX46_20365	COG1943	Transposase
EGX46_20385	COG0049	tRNA binding
EGX46_20390	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGX46_20410	COG2964	Protein conserved in bacteria
EGX46_20415	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX46_20430	COG1047	Peptidyl-prolyl cis-trans
EGX46_20435	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGX46_20445	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX46_20455	COG1216	Glycosyl transferase, family 2
EGX46_20465	COG2175	clavaminate synthase activity
EGX46_20470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX46_20480	COG4521	taurine ABC transporter
EGX46_20490	COG0429	hydrolase of the alpha beta-hydrolase fold
EGX46_20500	COG3954	Phosphoribulokinase
EGX46_20510	COG1765	OsmC-like protein
EGX46_20520	COG1289	transmembrane transporter activity
EGX46_20535	COG0433	COG0433 Predicted ATPase
EGX46_20540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX46_20545	COG1486	melibiose metabolic process
EGX46_20565	COG0402	S-adenosylhomocysteine deaminase activity
EGX46_20570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX46_20575	COG2146	nitrite reductase [NAD(P)H] activity
EGX46_20590	COG0180	Tryptophanyl-tRNA synthetase
EGX46_20595	COG0546	phosphoglycolate phosphatase activity
EGX46_20600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX46_20625	COG4796	Type ii and iii secretion system protein
EGX46_20655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGX46_20660	COG0494	nUDIX hydrolase
EGX46_20670	COG1011	Hydrolase
EGX46_20675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX46_20695	COG0745	RESPONSE REGULATOR receiver
EGX46_20700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX46_20705	COG2183	response to ionizing radiation
EGX46_20710	COG1918	ferrous iron import across plasma membrane
EGX46_20745	COG1640	4-alpha-glucanotransferase
EGX46_20750	COG0058	SHG alpha-glucan phosphorylase activity
EGX46_20755	COG0058	SHG alpha-glucan phosphorylase activity
EGX46_20775	COG1349	DNA-binding transcription factor activity
EGX46_20805	COG3300	MHYT domain
EGX46_20805	COG5001	Diguanylate cyclase
EGX46_20815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_20855	COG1943	Transposase
EGX46_20875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EGX46_20880	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX46_20885	COG4771	TonB-dependent receptor
EGX46_20905	COG3433	isochorismatase activity
EGX46_20905	COG2226	methyltransferase
EGX46_20905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX46_20910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX46_20915	COG3433	isochorismatase activity
EGX46_20915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX46_20915	COG2226	methyltransferase
EGX46_20945	COG1132	(ABC) transporter
EGX46_20965	COG2610	gluconate transmembrane transporter activity
EGX46_20980	COG3501	Rhs element vgr protein
EGX46_20990	COG3209	COG3209 Rhs family protein
EGX46_21010	COG0471	metal ion transport
EGX46_21095	COG3501	Rhs element vgr protein
EGX46_21110	COG3209	COG3209 Rhs family protein
EGX46_21140	COG3501	Rhs element vgr protein
EGX46_21155	COG3209	COG3209 Rhs family protein
EGX46_21210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGX46_21245	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EGX46_21250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX46_21260	COG1943	Transposase
EGX46_21265	COG1739	Uncharacterized protein family UPF0029
EGX46_21350	COG1943	Transposase
EGX46_21370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX46_21375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX46_21380	COG1494	fructose-1,6-bisphosphatase
EGX46_21390	COG3152	Membrane
EGX46_21405	COG0583	DNA-binding transcription factor activity
EGX46_21410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGX46_21415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGX46_21420	COG0471	metal ion transport
EGX46_21430	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGX46_21460	COG3678	ATP-independent chaperone mediated protein folding
EGX46_21465	COG0745	RESPONSE REGULATOR receiver
EGX46_21470	COG2205	protein histidine kinase activity
EGX46_21475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX46_21475	COG2169	Transcriptional regulator
EGX46_21480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGX46_21485	COG1045	serine acetyltransferase
EGX46_21505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX46_21510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX46_21520	COG4942	peptidase
EGX46_21535	COG0156	8-amino-7-oxononanoate synthase activity
EGX46_21545	COG0859	PFAM glycosyl transferase family 9
EGX46_21550	COG0859	PFAM glycosyl transferase family 9
EGX46_21555	COG1519	Transferase
EGX46_21575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX46_21595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX46_21620	COG1561	YicC-like family, N-terminal region
EGX46_21625	COG2860	membrane
EGX46_21645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX46_21650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX46_21655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX46_21665	COG0786	glutamate:sodium symporter activity
EGX46_21670	COG2233	PERMEase
EGX46_21675	COG2982	Protein involved in outer membrane biogenesis
EGX46_21680	COG0456	acetyltransferase
EGX46_21705	COG1295	ribonuclease BN
EGX46_21710	COG1011	Hydrolase
EGX46_21720	COG0174	glutamine synthetase
EGX46_21735	COG1943	Transposase
EGX46_21740	COG3852	Histidine kinase
EGX46_21750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX46_21775	COG1943	Transposase
EGX46_21780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX46_21780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX46_21785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX46_21790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGX46_21795	COG3084	Protein conserved in bacteria
EGX46_21805	COG1763	Mo-molybdopterin cofactor biosynthetic process
EGX46_21810	COG3328	transposase activity
EGX46_21845	COG2186	Transcriptional regulator
EGX46_21850	COG0477	Major facilitator Superfamily
EGX46_21865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_21915	COG1522	sequence-specific DNA binding
EGX46_21920	COG0716	FMN binding
EGX46_21940	COG3312	ion transport
EGX46_21995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGX46_22000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX46_22005	COG0573	inorganic phosphate transmembrane transporter activity
EGX46_22010	COG0581	inorganic phosphate transmembrane transporter activity
EGX46_22020	COG0704	Plays a role in the regulation of phosphate uptake
EGX46_22030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_22035	COG0765	amino acid transport
EGX46_22040	COG0765	amino acid transport
EGX46_22045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_22055	COG2252	PERMEase
EGX46_22090	COG0706	membrane insertase activity
EGX46_22105	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGX46_22125	COG0592	DNA-directed DNA polymerase activity
EGX46_22130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX46_22135	COG0187	DNA topoisomerase II activity
EGX46_22140	COG0561	phosphatase activity
EGX46_22160	COG3274	enterobacterial common antigen metabolic process
EGX46_22175	COG3121	Chaperone
EGX46_22185	COG1070	Carbohydrate kinase
EGX46_22195	COG4213	ABC transporter substrate-binding protein
EGX46_22205	COG4214	carbohydrate transport
EGX46_22210	COG2207	Transcriptional regulator
EGX46_22210	COG1609	Transcriptional regulator
EGX46_22215	COG0582	viral genome integration into host DNA
EGX46_22270	COG4604	ABC transporter, ATP-binding protein
EGX46_22275	COG4605	iron ion homeostasis
EGX46_22285	COG4607	ABC-type enterochelin transport system periplasmic component
EGX46_22315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX46_22330	COG2986	histidine ammonia-lyase
EGX46_22345	COG2194	sulfuric ester hydrolase activity
EGX46_22350	COG2197	response regulator
EGX46_22395	COG0564	pseudouridine synthase activity
EGX46_22400	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EGX46_22415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EGX46_22445	COG1943	Transposase
EGX46_22450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGX46_22460	COG2966	Psort location CytoplasmicMembrane, score
EGX46_22465	COG1280	lysine exporter protein (LysE YggA)
EGX46_22470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX46_22475	COG0505	Belongs to the CarA family
EGX46_22485	COG1943	Transposase
EGX46_22500	COG1047	Peptidyl-prolyl cis-trans
EGX46_22515	COG0196	riboflavin kinase activity
EGX46_22535	COG0583	DNA-binding transcription factor activity
EGX46_22555	COG1584	GPR1 FUN34 yaaH family protein
EGX46_22570	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGX46_22610	COG0745	RESPONSE REGULATOR receiver
EGX46_22615	COG3045	CreA protein
EGX46_22625	COG3708	Transcriptional regulator
EGX46_22625	COG2207	Transcriptional regulator
EGX46_22640	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EGX46_22645	COG0741	lytic transglycosylase activity
EGX46_22660	COG2199	diguanylate cyclase activity
EGX46_22665	COG2885	chlorophyll binding
EGX46_22700	COG3162	membrane
EGX46_22710	COG1301	dicarboxylic acid transport
EGX46_22820	COG2391	methyltransferase activity
EGX46_22825	COG0425	Belongs to the sulfur carrier protein TusA family
EGX46_22830	COG0583	DNA-binding transcription factor activity
EGX46_22835	COG0814	amino acid
EGX46_22840	COG0626	cystathionine gamma-synthase activity
EGX46_22850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_22855	COG4558	Periplasmic binding protein
EGX46_22860	COG3720	iron ion transport
EGX46_22865	COG4771	TonB-dependent receptor
EGX46_22875	COG0702	epimerase
EGX46_22880	COG3721	Heme iron utilization protein
EGX46_22905	COG1358	cellular component organization or biogenesis
EGX46_22965	COG3121	Chaperone
EGX46_23020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGX46_23030	COG0735	belongs to the Fur family
EGX46_23035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX46_23050	COG0305	Participates in initiation and elongation during chromosome replication
EGX46_23055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX46_23060	COG1448	Aminotransferase
EGX46_23065	COG2315	Protein conserved in bacteria
EGX46_23070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX46_23080	COG0629	single-stranded DNA binding
EGX46_23210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX46_23225	COG3344	reverse transcriptase
EGX46_23250	COG3328	transposase activity
EGX46_23355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX46_23365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGX46_23480	COG1943	Transposase
EGX46_23515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX46_23520	COG1475	DNA binding
EGX46_23525	COG1475	DNA binding
EGX46_23655	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGX46_23655	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGX46_23665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGX46_23680	COG1475	DNA binding
EGX46_23780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX46_23795	COG3344	reverse transcriptase
EGX46_23875	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGX46_23885	COG5301	cellulose 1,4-beta-cellobiosidase activity