locus-tag	class	description
CH55_1	COG3088	subunit of a heme lyase
CH55_1	COG4235	cytochrome complex assembly
CH55_10	COG2890	protein-(glutamine-N5) methyltransferase activity
CH55_1002	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH55_1003	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH55_1004	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH55_1005	COG1120	ATPase activity
CH55_1008	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH55_1009	COG0076	glutamate decarboxylase activity
CH55_1010	COG4114	ferric iron reductase
CH55_1011	COG1253	flavin adenine dinucleotide binding
CH55_1012	COG2982	Protein involved in outer membrane biogenesis
CH55_1015	COG0489	protein tyrosine kinase activity
CH55_1017	COG1943	Transposase
CH55_1022	COG2814	Major facilitator Superfamily
CH55_1024	COG1346	cytolysis
CH55_1027	COG2949	membrane
CH55_1028	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH55_1031	COG2311	Membrane
CH55_1033	COG0477	Major facilitator Superfamily
CH55_1034	COG0583	DNA-binding transcription factor activity
CH55_104	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH55_1040	COG1136	(ABC) transporter
CH55_1042	COG0303	'Molybdopterin
CH55_1044	COG3328	transposase activity
CH55_1045	COG3328	transposase activity
CH55_1047	COG0488	(ABC) transporter
CH55_1076	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH55_1077	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH55_1079	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_108	COG1063	alcohol dehydrogenase
CH55_1080	COG1024	Enoyl-CoA hydratase
CH55_1082	COG3425	synthase
CH55_1083	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_1084	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH55_1085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH55_1087	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_109	COG1879	ABC-type sugar transport system periplasmic component
CH55_1095	COG2920	part of a sulfur-relay system
CH55_1099	COG1832	CoA-binding protein
CH55_110	COG1129	ABC transporter
CH55_1100	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CH55_1102	COG0210	DNA helicase
CH55_1103	COG3304	Inner membrane component domain
CH55_1104	COG1289	transmembrane transporter activity
CH55_1105	COG3070	regulator of competence-specific genes
CH55_1107	COG2885	chlorophyll binding
CH55_1107	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH55_1108	COG1943	Transposase
CH55_111	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_1110	COG1067	ATP-dependent peptidase activity
CH55_1113	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH55_1117	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH55_1118	COG1943	Transposase
CH55_1119	COG3009	Protein conserved in bacteria
CH55_112	COG1609	Transcriptional regulator
CH55_1120	COG3008	intermembrane lipid transfer
CH55_1120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH55_1121	COG2995	paraquat-inducible protein a
CH55_1122	COG0488	(ABC) transporter
CH55_1124	COG3217	Mosc domain protein beta barrel domain protein
CH55_1124	COG0633	Ferredoxin
CH55_1127	COG0308	aminopeptidase N
CH55_113	COG0583	DNA-binding transcription factor activity
CH55_1131	COG1448	Aminotransferase
CH55_1132	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH55_1133	COG3108	Peptidase M15
CH55_1134	COG2989	Protein conserved in bacteria
CH55_1135	COG1943	Transposase
CH55_1137	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CH55_1138	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH55_1139	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH55_114	COG0473	3-isopropylmalate dehydrogenase activity
CH55_1140	COG3173	Aminoglycoside phosphotransferase
CH55_1142	COG2835	tetraacyldisaccharide 4'-kinase activity
CH55_1143	COG1278	Cold shock
CH55_1144	COG5383	Protein conserved in bacteria
CH55_1147	COG0658	competence protein
CH55_1147	COG2333	competence protein COMEC
CH55_115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH55_1151	COG0539	negative regulation of cytoplasmic translation
CH55_1156	COG5295	Hep Hag repeat protein
CH55_1156	COG5295	Hep Hag repeat protein
CH55_1157	COG0252	asparaginase activity
CH55_1158	COG1944	ATP diphosphatase activity
CH55_1159	COG2116	formate transmembrane transporter activity
CH55_116	COG4638	Rieske (2fe-2S)
CH55_1160	COG1882	Formate acetyltransferase
CH55_1162	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH55_1163	COG2814	Major facilitator Superfamily
CH55_1166	COG2814	Major facilitator Superfamily
CH55_1168	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH55_117	COG4638	Rieske (2fe-2S)
CH55_1171	COG1674	ftsk spoiiie
CH55_1171	COG3107	peptidoglycan biosynthetic process
CH55_1173	COG0492	ferredoxin-NADP+ reductase activity
CH55_1175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH55_1178	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH55_1179	COG1943	Transposase
CH55_118	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH55_1180	COG0542	response to heat
CH55_1182	COG1278	Cold shock
CH55_1184	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH55_1185	COG2990	Protein conserved in bacteria
CH55_1186	COG3593	DNA synthesis involved in DNA repair
CH55_1187	COG2431	L-lysine efflux transmembrane transporter activity
CH55_1189	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH55_119	COG2831	hemolysin activation secretion protein
CH55_1190	COG0028	Belongs to the TPP enzyme family
CH55_1191	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH55_1192	COG0702	epimerase
CH55_1193	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH55_1195	COG1605	Chorismate mutase
CH55_1196	COG1126	abc transporter atp-binding protein
CH55_1197	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH55_1198	COG4215	(ABC) transporter
CH55_1199	COG4160	amino acid transport
CH55_120	COG3210	domain, Protein
CH55_1203	COG1120	ATPase activity
CH55_1204	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH55_1209	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH55_121	COG3210	domain, Protein
CH55_1212	COG1177	transmembrane transport
CH55_1213	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH55_1214	COG3842	ATPase activity
CH55_1215	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH55_1218	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH55_1219	COG0569	domain protein
CH55_1219	COG2985	domain, Protein
CH55_1221	COG0671	phosphoesterase, PA-phosphatase related
CH55_1222	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH55_1223	COG1349	DNA-binding transcription factor activity
CH55_1224	COG0814	amino acid
CH55_1225	COG0814	amino acid
CH55_1226	COG1686	Belongs to the peptidase S11 family
CH55_1227	COG2011	ABC-type metal ion transport system permease component
CH55_1232	COG0625	glutathione transferase activity
CH55_1233	COG4771	TonB-dependent receptor
CH55_1235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH55_1237	COG0833	amino acid
CH55_1238	COG0833	amino acid
CH55_124	COG3210	domain, Protein
CH55_1240	COG0583	DNA-binding transcription factor activity
CH55_1241	COG2855	membrane
CH55_1243	COG3188	usher protein
CH55_1244	COG3121	Chaperone
CH55_1247	COG3710	Transcriptional regulator
CH55_1248	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH55_1248	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH55_1248	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH55_1249	COG1105	Belongs to the carbohydrate kinase PfkB family
CH55_1251	COG0494	nUDIX hydrolase
CH55_1252	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_1253	COG1129	ABC transporter
CH55_1255	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH55_1260	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_1264	COG1312	Catalyzes the dehydration of D-mannonate
CH55_1265	COG0246	Mannitol dehydrogenase
CH55_1266	COG2186	Transcriptional regulator
CH55_1268	COG0523	cobalamin synthesis protein
CH55_1269	COG0671	phosphoesterase, PA-phosphatase related
CH55_127	COG3210	domain, Protein
CH55_1270	COG0791	NLP P60 protein
CH55_1272	COG2200	EAL domain
CH55_1273	COG4166	transmembrane transport
CH55_1274	COG4174	ABC transporter (Permease)
CH55_1275	COG4239	(ABC) transporter, permease
CH55_1276	COG4172	Belongs to the ABC transporter superfamily
CH55_1278	COG2814	Major facilitator Superfamily
CH55_1279	COG1187	pseudouridine synthase activity
CH55_1280	COG1061	Type III restriction enzyme res subunit
CH55_1283	COG1943	Transposase
CH55_1285	COG3082	Protein of unknown function (DUF1414)
CH55_1286	COG3083	sulfuric ester hydrolase activity
CH55_1289	COG3157	Type VI secretion system effector, Hcp
CH55_129	COG3842	ATPase activity
CH55_1293	COG2723	6-phospho-beta-galactosidase activity
CH55_1295	COG1737	Transcriptional regulator
CH55_1299	COG3299	homolog of phage Mu protein gp47
CH55_13	COG0730	response to heat
CH55_1307	COG4386	tail sheath protein
CH55_131	COG1609	Transcriptional regulator
CH55_1311	COG3622	Belongs to the hyi family
CH55_1312	COG1349	DNA-binding transcription factor activity
CH55_1313	COG0235	Class ii aldolase
CH55_1314	COG3395	kinase activity
CH55_1322	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH55_1325	COG1943	Transposase
CH55_1326	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CH55_1328	COG2223	nitrite transmembrane transporter activity
CH55_1329	COG0642	Histidine kinase
CH55_1329	COG2198	Histidine kinase
CH55_1330	COG2198	Histidine kinase
CH55_1330	COG0642	Histidine kinase
CH55_1332	COG0784	Response regulator, receiver
CH55_1332	COG2205	protein histidine kinase activity
CH55_1337	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH55_134	COG0395	ABC-type sugar transport system, permease component
CH55_1340	COG0814	amino acid
CH55_1343	COG1199	ATP-dependent helicase activity
CH55_1345	COG0697	spore germination
CH55_1347	COG1982	Orn Lys Arg decarboxylase major
CH55_1348	COG0531	amino acid
CH55_1349	COG1174	glycine betaine transport
CH55_135	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH55_1350	COG1125	glycine betaine transport
CH55_1351	COG1174	glycine betaine transport
CH55_1352	COG1732	Glycine betaine
CH55_1353	COG1732	Glycine betaine
CH55_1354	COG2897	thiosulfate sulfurtransferase activity
CH55_1357	COG0410	ABC transporter
CH55_1358	COG1122	ATPase activity
CH55_1361	COG4807	Protein conserved in bacteria
CH55_1365	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH55_1367	COG2261	transglycosylase associated protein
CH55_1369	COG1403	HNH endonuclease
CH55_1371	COG0277	FAD linked oxidase domain protein
CH55_1372	COG1686	Belongs to the peptidase S11 family
CH55_1374	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH55_1376	COG1943	Transposase
CH55_1377	COG0513	Belongs to the DEAD box helicase family
CH55_1378	COG3328	transposase activity
CH55_1385	COG1943	Transposase
CH55_1387	COG0516	GMP reductase activity
CH55_1387	COG0517	IMP dehydrogenase activity
CH55_1389	COG1645	bacterial-type flagellum-dependent swarming motility
CH55_139	COG0668	transmembrane transport
CH55_1392	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH55_1393	COG2976	Protein conserved in bacteria
CH55_14	COG3101	peptidyl-lysine hydroxylation
CH55_140	COG1518	maintenance of DNA repeat elements
CH55_1402	COG3468	outer membrane autotransporter barrel domain protein
CH55_1403	COG3468	outer membrane autotransporter barrel domain protein
CH55_1407	COG2975	iron-sulfur cluster assembly
CH55_1408	COG0633	Ferredoxin
CH55_1409	COG0443	Heat shock 70 kDa protein
CH55_141	COG1203	CRISPR-associated helicase, Cas3
CH55_1412	COG0822	iron-sulfur transferase activity
CH55_1413	COG1104	cysteine desulfurase activity
CH55_1416	COG0483	inositol monophosphate 1-phosphatase activity
CH55_1417	COG1943	Transposase
CH55_1418	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH55_1419	COG3683	transport system, periplasmic component
CH55_1420	COG2814	Major facilitator Superfamily
CH55_1421	COG3711	transcriptional antiterminator
CH55_1424	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH55_1424	COG1017	nitric oxide dioxygenase activity
CH55_1425	COG2188	Transcriptional regulator
CH55_1426	COG2188	Transcriptional regulator
CH55_1427	COG0347	Belongs to the P(II) protein family
CH55_1428	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH55_1428	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH55_1429	COG2204	response regulator
CH55_1430	COG3170	Tfp pilus assembly protein FimV
CH55_1431	COG2205	protein histidine kinase activity
CH55_1432	COG1943	Transposase
CH55_1438	COG0590	tRNA wobble adenosine to inosine editing
CH55_1439	COG0560	Phosphoserine phosphatase
CH55_1441	COG1737	Transcriptional regulator
CH55_1442	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH55_1443	COG1943	Transposase
CH55_1445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH55_1449	COG0681	Belongs to the peptidase S26 family
CH55_1452	COG3086	response to oxidative stress
CH55_1453	COG3026	antisigma factor binding
CH55_1454	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH55_1456	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH55_1458	COG0513	Belongs to the DEAD box helicase family
CH55_146	COG0667	Aldo Keto reductase
CH55_1469	COG1984	allophanate hydrolase subunit 2
CH55_1470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH55_1472	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH55_1473	COG5212	phosphodiesterase
CH55_1475	COG3272	Protein of unknown function (DUF1722)
CH55_1480	COG2205	protein histidine kinase activity
CH55_1481	COG0745	RESPONSE REGULATOR receiver
CH55_1485	COG0033	Phosphoglucomutase
CH55_1486	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH55_149	COG0477	Major facilitator Superfamily
CH55_1490	COG1917	Cupin 2, conserved barrel domain protein
CH55_1490	COG2169	Transcriptional regulator
CH55_1491	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH55_1492	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH55_1493	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH55_1494	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH55_1495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH55_1496	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH55_1498	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH55_1499	COG4413	Urea transporter
CH55_1501	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH55_1508	COG1124	(ABC) transporter
CH55_1509	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH55_151	COG0583	DNA-binding transcription factor activity
CH55_1510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH55_1512	COG0747	negative chemotaxis
CH55_1513	COG1278	Cold shock
CH55_152	COG3916	Acyl-homoserine-lactone synthase
CH55_1521	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH55_1522	COG4175	Glycine betaine
CH55_1523	COG4176	ABC-type proline glycine betaine transport system permease component
CH55_1524	COG2113	Glycine betaine
CH55_1529	COG0582	viral genome integration into host DNA
CH55_153	COG2771	luxR family
CH55_1530	COG2963	transposase activity
CH55_1532	COG0596	Alpha beta hydrolase
CH55_1536	COG0735	belongs to the Fur family
CH55_1541	COG1943	Transposase
CH55_1542	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH55_1542	COG1263	PTS System
CH55_1542	COG2190	(PTS) system
CH55_1544	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH55_1545	COG1846	Transcriptional regulator
CH55_1545	COG1940	carbohydrate kinase activity
CH55_1546	COG0647	UMP catabolic process
CH55_1547	COG0367	asparagine synthase
CH55_1554	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH55_1556	COG1702	phosphate starvation-inducible protein PhoH
CH55_1558	COG4535	Mg2 and Co2 transporter CorC
CH55_1559	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH55_1561	COG0765	amino acid transport
CH55_1562	COG0765	amino acid transport
CH55_1563	COG1126	abc transporter atp-binding protein
CH55_1564	COG2888	peptidyl-tyrosine sulfation
CH55_1567	COG1466	dna polymerase III delta subunit
CH55_1569	COG0799	negative regulation of ribosome biogenesis
CH55_157	COG0628	permease
CH55_1571	COG0768	penicillin binding
CH55_1572	COG0772	Belongs to the SEDS family
CH55_1573	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH55_1574	COG1686	Belongs to the peptidase S11 family
CH55_1575	COG1686	Belongs to the peptidase S11 family
CH55_1579	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH55_1580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH55_1581	COG1278	Cold shock
CH55_1582	COG1278	Cold shock
CH55_1583	COG2197	response regulator
CH55_1588	COG5265	(ABC) transporter
CH55_1590	COG3718	enzyme involved in inositol metabolism
CH55_1592	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH55_1593	COG0673	inositol 2-dehydrogenase activity
CH55_1594	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_1595	COG1129	ABC transporter
CH55_1596	COG1879	ABC-type sugar transport system periplasmic component
CH55_1597	COG0673	inositol 2-dehydrogenase activity
CH55_1598	COG0673	inositol 2-dehydrogenase activity
CH55_1599	COG3962	Belongs to the TPP enzyme family
CH55_1605	COG2373	Large extracellular alpha-helical protein
CH55_1607	COG1943	Transposase
CH55_1609	COG4953	penicillin-binding protein 1C
CH55_161	COG3328	transposase activity
CH55_1610	COG3423	Transcriptional regulator
CH55_1621	COG2850	peptidyl-arginine hydroxylation
CH55_1622	COG3328	transposase activity
CH55_1627	COG0656	L-ascorbic acid biosynthetic process
CH55_1628	COG0667	Aldo Keto reductase
CH55_1635	COG2453	phosphatase
CH55_1635	COG0671	phosphoesterase, PA-phosphatase related
CH55_1636	COG2267	carboxylic ester hydrolase activity
CH55_1638	COG4589	Belongs to the CDS family
CH55_1639	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH55_164	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH55_1647	COG2501	S4 domain
CH55_1648	COG1943	Transposase
CH55_165	COG3328	transposase activity
CH55_1651	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH55_1653	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH55_1654	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH55_1655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH55_1656	COG4181	ATPase activity
CH55_1657	COG2755	lipolytic protein G-D-S-L family
CH55_1658	COG0300	oxidoreductase activity
CH55_1659	COG3118	belongs to the thioredoxin family
CH55_166	COG1530	ribonuclease E activity
CH55_1660	COG0330	HflC and HflK could
CH55_1661	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH55_1662	COG0789	Transcriptional regulator
CH55_1663	COG2217	Heavy metal translocating P-type atpase
CH55_1664	COG3735	TraB family
CH55_1665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH55_1668	COG0737	Belongs to the 5'-nucleotidase family
CH55_1669	COG0737	Belongs to the 5'-nucleotidase family
CH55_167	COG0564	pseudouridine synthase activity
CH55_1670	COG0737	Belongs to the 5'-nucleotidase family
CH55_1671	COG0737	Belongs to the 5'-nucleotidase family
CH55_1672	COG2223	nitrite transmembrane transporter activity
CH55_1673	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH55_1673	COG4651	solute:proton antiporter activity
CH55_1674	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH55_1675	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH55_1679	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH55_1680	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH55_1681	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH55_169	COG1399	metal-binding, possibly nucleic acid-binding protein
CH55_1690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH55_1694	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH55_1694	COG0543	2 iron, 2 sulfur cluster binding
CH55_1695	COG0543	2 iron, 2 sulfur cluster binding
CH55_1695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH55_17	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH55_170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH55_1701	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH55_1703	COG2832	Protein of unknown function (DUF454)
CH55_1706	COG3264	Mechanosensitive ion channel
CH55_1706	COG1196	nuclear chromosome segregation
CH55_1707	COG1196	nuclear chromosome segregation
CH55_1707	COG3264	Mechanosensitive ion channel
CH55_1708	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH55_1709	COG1309	transcriptional regulator
CH55_1710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH55_1711	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH55_1713	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH55_1717	COG3695	enzyme binding
CH55_1718	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH55_1719	COG1946	Acyl-CoA thioesterase
CH55_1720	COG0004	ammonium transporteR
CH55_1721	COG0347	Belongs to the P(II) protein family
CH55_1722	COG1132	(ABC) transporter
CH55_1723	COG1132	(ABC) transporter
CH55_1724	COG1522	sequence-specific DNA binding
CH55_1727	COG4533	DNA binding
CH55_1729	COG0824	Thioesterase
CH55_1730	COG1555	photosystem II stabilization
CH55_1731	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH55_1732	COG0776	regulation of translation
CH55_1733	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH55_1738	COG0271	Belongs to the BolA IbaG family
CH55_1739	COG3056	Lipoprotein
CH55_174	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_1740	COG2223	nitrite transmembrane transporter activity
CH55_1742	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH55_1743	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH55_1744	COG1845	cytochrome c oxidase, subunit III
CH55_1745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH55_1747	COG2814	Major facilitator Superfamily
CH55_1749	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH55_1750	COG0693	protein deglycase activity
CH55_1753	COG0142	geranyltranstransferase activity
CH55_1755	COG1943	Transposase
CH55_1756	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH55_1757	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH55_176	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH55_1760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH55_1760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH55_1764	COG1943	Transposase
CH55_1765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH55_1766	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH55_1767	COG1862	Preprotein translocase
CH55_1769	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CH55_1770	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CH55_1771	COG0450	alkyl hydroperoxide reductase
CH55_1775	COG0366	Alpha amylase catalytic
CH55_1777	COG1114	Component of the transport system for branched-chain amino acids
CH55_1779	COG5002	protein histidine kinase activity
CH55_1780	COG0745	RESPONSE REGULATOR receiver
CH55_1781	COG0420	3'-5' exonuclease activity
CH55_1782	COG0419	ATPase involved in DNA repair
CH55_1783	COG1940	carbohydrate kinase activity
CH55_179	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH55_1790	COG2226	methyltransferase
CH55_1793	COG1943	Transposase
CH55_18	COG1794	racemase activity, acting on amino acids and derivatives
CH55_180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH55_1801	COG1943	Transposase
CH55_1803	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH55_1807	COG1477	protein flavinylation
CH55_1811	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH55_1812	COG1805	sodium ion transport
CH55_1813	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH55_1814	COG0121	glutamine amidotransferase
CH55_1815	COG3034	peptidoglycan biosynthetic process
CH55_1817	COG1960	acyl-CoA dehydrogenase activity
CH55_1819	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH55_182	COG0470	DNA polymerase III
CH55_1823	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH55_183	COG0084	hydrolase, TatD family'
CH55_1832	COG2814	Major facilitator Superfamily
CH55_1833	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH55_1835	COG1846	Transcriptional regulator
CH55_1836	COG1566	PFAM secretion protein HlyD family protein
CH55_1837	COG2814	Major facilitator Superfamily
CH55_1838	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH55_1839	COG3118	belongs to the thioredoxin family
CH55_184	COG1263	PTS System
CH55_184	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH55_1841	COG1042	CoA-binding domain protein
CH55_1841	COG0045	succinate-CoA ligase (ADP-forming) activity
CH55_1841	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH55_1842	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH55_1843	COG5544	Lipoprotein
CH55_1849	COG0542	response to heat
CH55_185	COG1943	Transposase
CH55_1851	COG0564	pseudouridine synthase activity
CH55_1852	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH55_1853	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH55_1854	COG1943	Transposase
CH55_1855	COG1605	Chorismate mutase
CH55_1855	COG0077	Prephenate dehydratase
CH55_1858	COG1605	Chorismate mutase
CH55_1858	COG0077	Prephenate dehydratase
CH55_1859	COG0287	Prephenate dehydrogenase
CH55_1859	COG1605	Chorismate mutase
CH55_186	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH55_1860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH55_1861	COG3279	Response regulator of the LytR AlgR family
CH55_1862	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH55_1863	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH55_1864	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH55_1865	COG3137	Salt-induced outer membrane protein
CH55_1867	COG1943	Transposase
CH55_187	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH55_1872	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH55_1873	COG4137	Cytochrome C assembly protein
CH55_1874	COG4536	flavin adenine dinucleotide binding
CH55_1875	COG1943	Transposase
CH55_1877	COG2918	glutathione biosynthetic process
CH55_1878	COG1238	metal cluster binding
CH55_1879	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH55_188	COG0537	adenosine 5'-monophosphoramidase activity
CH55_1884	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH55_1885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH55_189	COG5633	Lipoprotein
CH55_1892	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH55_1893	COG3958	Transketolase
CH55_1894	COG3959	Transketolase, thiamine diphosphate binding domain
CH55_1895	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_1896	COG1129	ABC transporter
CH55_1900	COG3783	Cytochrome b(562)
CH55_1901	COG3038	cytochrome b561
CH55_1902	COG3381	protein complex oligomerization
CH55_1903	COG3302	dmso reductase anchor subunit
CH55_1904	COG0437	4 iron, 4 sulfur cluster binding
CH55_1905	COG0243	molybdopterin cofactor binding
CH55_1906	COG0235	Class ii aldolase
CH55_1907	COG1349	DNA-binding transcription factor activity
CH55_1909	COG1943	Transposase
CH55_1910	COG1129	ABC transporter
CH55_1911	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_1912	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_1913	COG3623	hexulose-6-phosphate isomerase
CH55_1914	COG1070	Carbohydrate kinase
CH55_1915	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH55_1915	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH55_1917	COG0024	Methionine aminopeptidase
CH55_1919	COG4771	TonB-dependent receptor
CH55_192	COG1472	Belongs to the glycosyl hydrolase 3 family
CH55_1921	COG1858	cytochrome C peroxidase
CH55_1922	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH55_1926	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH55_1929	COG2376	Dihydroxyacetone kinase
CH55_1930	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_1931	COG1063	alcohol dehydrogenase
CH55_1932	COG0698	ribose 5-phosphate isomerase
CH55_1933	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH55_1934	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH55_1935	COG1388	LysM domain
CH55_1935	COG4942	peptidase
CH55_194	COG1252	NADH dehydrogenase
CH55_1940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CH55_1943	COG0529	Catalyzes the synthesis of activated sulfate
CH55_1954	COG0720	synthase
CH55_1955	COG0602	queuosine metabolic process
CH55_1959	COG3956	TIGRFAM MazG family protein
CH55_1960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH55_1961	COG4999	Histidine kinase
CH55_1961	COG2205	protein histidine kinase activity
CH55_1961	COG3850	Histidine kinase
CH55_1961	COG3437	response regulator, receiver
CH55_1962	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH55_1964	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH55_1966	COG2860	membrane
CH55_1970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH55_1971	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH55_1972	COG1120	ATPase activity
CH55_1973	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH55_1974	COG1643	Atp-dependent helicase
CH55_1975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH55_1977	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH55_1978	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH55_1979	COG0617	tRNA 3'-terminal CCA addition
CH55_198	COG3328	transposase activity
CH55_1980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH55_1984	COG0726	polysaccharide deacetylase
CH55_1986	COG0842	Transport permease protein
CH55_1987	COG1131	(ABC) transporter
CH55_1988	COG0288	reversible hydration of carbon dioxide
CH55_1989	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH55_199	COG3134	Outer membrane lipoprotein
CH55_1990	COG2132	Multicopper oxidase
CH55_1994	COG0697	spore germination
CH55_1996	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH55_1997	COG1943	Transposase
CH55_1998	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH55_1999	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH55_2	COG3088	subunit of a heme lyase
CH55_2	COG4235	cytochrome complex assembly
CH55_200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH55_2000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH55_2001	COG2186	Transcriptional regulator
CH55_2002	COG1113	amino acid transport
CH55_2003	COG3725	Membrane protein required for beta-lactamase induction
CH55_2004	COG3725	Membrane protein required for beta-lactamase induction
CH55_2005	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH55_2007	COG4969	Belongs to the N-Me-Phe pilin family
CH55_2008	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH55_2009	COG1459	type II secretion system
CH55_201	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH55_2011	COG0237	dephospho-CoA kinase activity
CH55_2014	COG1943	Transposase
CH55_2019	COG0582	viral genome integration into host DNA
CH55_2021	COG0795	lipopolysaccharide-transporting ATPase activity
CH55_2022	COG0795	lipopolysaccharide-transporting ATPase activity
CH55_2024	COG2927	DNA polymerase III (CHI subunit)
CH55_2025	COG0525	valine-tRNA ligase activity
CH55_2027	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH55_2028	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CH55_2029	COG2731	YhcH YjgK YiaL family protein
CH55_203	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH55_2032	COG0601	transmembrane transport
CH55_2033	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH55_2034	COG0444	Belongs to the ABC transporter superfamily
CH55_2035	COG4608	Belongs to the ABC transporter superfamily
CH55_2039	COG2188	Transcriptional regulator
CH55_2040	COG3624	Phosphonate C-P lyase system protein PhnG
CH55_2041	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH55_2042	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH55_2043	COG3626	phosphonate metabolism
CH55_2044	COG3627	carbon phosphorus lyase activity
CH55_2045	COG4107	phosphonate C-P lyase system protein PhnK
CH55_2046	COG4778	phosphonate C-P lyase system protein PhnL
CH55_2047	COG3454	Phosphonate metabolism
CH55_2048	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH55_2049	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH55_205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH55_2050	COG0702	epimerase
CH55_2053	COG3842	ATPase activity
CH55_2054	COG0395	ABC-type sugar transport system, permease component
CH55_2056	COG1653	transport
CH55_2060	COG3153	acetyltransferase
CH55_2065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH55_2067	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH55_2068	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH55_207	COG2850	peptidyl-arginine hydroxylation
CH55_2070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH55_2073	COG0513	Belongs to the DEAD box helicase family
CH55_2076	COG2801	Transposase and inactivated derivatives
CH55_2079	COG3710	Transcriptional regulator
CH55_2083	COG1256	bacterial-type flagellum assembly
CH55_2085	COG1706	bacterial-type flagellum-dependent cell motility
CH55_2086	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH55_2087	COG4786	Flagellar basal body rod
CH55_2088	COG4787	bacterial-type flagellum-dependent cell motility
CH55_2089	COG1749	Flagellar hook protein flgE
CH55_209	COG0745	RESPONSE REGULATOR receiver
CH55_2090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH55_2091	COG1558	bacterial-type flagellum-dependent cell motility
CH55_2092	COG1815	bacterial-type flagellum-dependent cell motility
CH55_2093	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH55_21	COG0697	spore germination
CH55_2102	COG2204	response regulator
CH55_2106	COG1987	bacterial-type flagellum assembly
CH55_2107	COG1684	flagellar biosynthetic protein fliR
CH55_2108	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH55_211	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH55_2112	COG4592	Periplasmic binding protein
CH55_2116	COG1943	Transposase
CH55_2119	COG4964	Belongs to the GSP D family
CH55_2120	COG4964	Belongs to the GSP D family
CH55_2130	COG0848	biopolymer transport protein
CH55_2132	COG0811	peptide transport
CH55_2133	COG0626	cystathionine gamma-synthase activity
CH55_2134	COG0586	Pfam SNARE associated Golgi protein
CH55_2135	COG2207	Transcriptional regulator
CH55_2136	COG1979	alcohol dehydrogenase
CH55_2137	COG0656	L-ascorbic acid biosynthetic process
CH55_2140	COG2132	Multicopper oxidase
CH55_2141	COG0204	Acyl-transferase
CH55_2142	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH55_2143	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH55_2144	COG0583	DNA-binding transcription factor activity
CH55_2145	COG0187	DNA topoisomerase II activity
CH55_2146	COG3150	esterase
CH55_2147	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH55_2148	COG3151	Protein conserved in bacteria
CH55_2149	COG0494	nUDIX hydrolase
CH55_215	COG1187	pseudouridine synthase activity
CH55_2150	COG1538	Outer membrane efflux protein
CH55_2153	COG0754	glutathionylspermidine amidase activity
CH55_2154	COG3384	dioxygenase
CH55_2158	COG0531	amino acid
CH55_216	COG0538	isocitrate dehydrogenase activity
CH55_2161	COG3025	triphosphatase activity
CH55_2162	COG4991	sh3 domain protein
CH55_2165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH55_2169	COG0358	DNA primase activity
CH55_2170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH55_2185	COG0251	oxidation-reduction process
CH55_219	COG0840	transmembrane signaling receptor activity
CH55_2194	COG1289	transmembrane transporter activity
CH55_2198	COG0395	ABC-type sugar transport system, permease component
CH55_220	COG0702	epimerase
CH55_2200	COG1653	transport
CH55_2201	COG1609	Transcriptional regulator
CH55_2202	COG3459	Glycosyltransferase 36 associated
CH55_2203	COG3842	ATPase activity
CH55_2207	COG3210	domain, Protein
CH55_2209	COG3210	domain, Protein
CH55_221	COG1733	regulation of RNA biosynthetic process
CH55_2211	COG3210	domain, Protein
CH55_2212	COG3210	domain, Protein
CH55_2213	COG3210	domain, Protein
CH55_2214	COG2831	hemolysin activation secretion protein
CH55_2215	COG4245	von Willebrand factor, type A
CH55_2218	COG4245	von Willebrand factor, type A
CH55_2221	COG3247	response to pH
CH55_2222	COG1902	pentaerythritol trinitrate reductase activity
CH55_2222	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH55_2226	COG1451	nucleotide metabolic process
CH55_2227	COG0673	inositol 2-dehydrogenase activity
CH55_2230	COG1943	Transposase
CH55_2235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH55_2236	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH55_2238	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH55_2239	COG0564	pseudouridine synthase activity
CH55_2249	COG3501	Rhs element vgr protein
CH55_2257	COG2885	chlorophyll binding
CH55_2257	COG3047	cAMP biosynthetic process
CH55_226	COG1522	sequence-specific DNA binding
CH55_2261	COG0417	DNA replication proofreading
CH55_2262	COG0586	Pfam SNARE associated Golgi protein
CH55_2264	COG1178	ABC-type Fe3 transport system permease component
CH55_2265	COG4143	(ABC) transporter
CH55_2268	COG2814	Major facilitator Superfamily
CH55_2271	COG0473	3-isopropylmalate dehydrogenase activity
CH55_2277	COG1022	Amp-dependent synthetase and ligase
CH55_2278	COG0028	Belongs to the TPP enzyme family
CH55_228	COG3321	synthase
CH55_228	COG0604	alcohol dehydrogenase
CH55_228	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_2280	COG1943	Transposase
CH55_2281	COG1609	Transcriptional regulator
CH55_2285	COG3116	cell division
CH55_2286	COG0768	penicillin binding
CH55_2287	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH55_2288	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH55_2291	COG0772	Belongs to the SEDS family
CH55_2295	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH55_2296	COG0849	cell division
CH55_2297	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH55_230	COG1278	Cold shock
CH55_2302	COG0494	nUDIX hydrolase
CH55_2305	COG0435	Glutathione S-transferase
CH55_2306	COG2259	Doxx family
CH55_2308	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH55_2309	COG4575	ribosome binding
CH55_2312	COG0586	Pfam SNARE associated Golgi protein
CH55_2315	COG2271	Major facilitator Superfamily
CH55_2317	COG0246	Mannitol dehydrogenase
CH55_2318	COG2721	sulfolactate sulfo-lyase activity
CH55_232	COG0840	transmembrane signaling receptor activity
CH55_2320	COG1943	Transposase
CH55_2321	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH55_2323	COG2966	Psort location CytoplasmicMembrane, score
CH55_2324	COG1280	lysine exporter protein (LysE YggA)
CH55_2325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH55_2326	COG0505	Belongs to the CarA family
CH55_2328	COG1943	Transposase
CH55_233	COG0840	transmembrane signaling receptor activity
CH55_2330	COG1047	Peptidyl-prolyl cis-trans
CH55_2333	COG0196	riboflavin kinase activity
CH55_2335	COG0583	DNA-binding transcription factor activity
CH55_2339	COG1584	GPR1 FUN34 yaaH family protein
CH55_234	COG1285	pathogenesis
CH55_2342	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH55_2350	COG0745	RESPONSE REGULATOR receiver
CH55_2351	COG3045	CreA protein
CH55_2354	COG2207	Transcriptional regulator
CH55_2354	COG3708	Transcriptional regulator
CH55_2355	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH55_2357	COG0741	lytic transglycosylase activity
CH55_2360	COG2199	diguanylate cyclase activity
CH55_2361	COG2885	chlorophyll binding
CH55_2362	COG0488	(ABC) transporter
CH55_2363	COG0488	(ABC) transporter
CH55_2367	COG0560	Phosphoserine phosphatase
CH55_2368	COG3726	membrane protein affecting hemolysin expression
CH55_2373	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH55_2374	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH55_2375	COG0084	hydrolase, TatD family'
CH55_2376	COG0084	hydrolase, TatD family'
CH55_2377	COG4667	esterase of the alpha-beta hydrolase superfamily
CH55_2379	COG2823	Periplasmic or secreted lipoprotein
CH55_2381	COG0456	acetyltransferase
CH55_2382	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH55_2386	COG3706	GGDEF domain
CH55_2389	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH55_2390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH55_2393	COG0859	PFAM glycosyl transferase family 9
CH55_2395	COG2390	Transcriptional regulator
CH55_2396	COG2390	Transcriptional regulator
CH55_24	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH55_240	COG1360	Flagellar Motor Protein
CH55_2405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_2405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_2405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH55_2406	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH55_2407	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH55_2408	COG2207	Transcriptional regulator
CH55_2409	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH55_241	COG0643	Histidine kinase
CH55_241	COG2198	Histidine kinase
CH55_2411	COG4269	membrane
CH55_242	COG0835	chemotaxis
CH55_2421	COG2963	transposase activity
CH55_2423	COG1401	restriction endodeoxyribonuclease activity
CH55_2428	COG1295	ribonuclease BN
CH55_2429	COG1011	Hydrolase
CH55_243	COG2271	Major facilitator Superfamily
CH55_2431	COG0174	glutamine synthetase
CH55_2432	COG3852	Histidine kinase
CH55_2434	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH55_2437	COG1943	Transposase
CH55_2438	COG1943	Transposase
CH55_2439	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH55_2439	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH55_244	COG0251	oxidation-reduction process
CH55_2440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH55_2441	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH55_2442	COG3084	Protein conserved in bacteria
CH55_2444	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH55_2445	COG3328	transposase activity
CH55_2455	COG0435	Glutathione S-transferase
CH55_2456	COG0583	DNA-binding transcription factor activity
CH55_2457	COG1741	Belongs to the pirin family
CH55_2458	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH55_246	COG2964	Protein conserved in bacteria
CH55_2462	COG2823	Periplasmic or secreted lipoprotein
CH55_2464	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH55_2465	COG5002	protein histidine kinase activity
CH55_2465	COG0784	Response regulator, receiver
CH55_2465	COG2198	Histidine kinase
CH55_2466	COG1242	4 iron, 4 sulfur cluster binding
CH55_2467	COG0069	glutamate synthase activity
CH55_2467	COG0067	glutamate synthase
CH55_2467	COG0070	glutamate synthase
CH55_2468	COG0493	'glutamate synthase
CH55_2469	COG0493	'glutamate synthase
CH55_2471	COG2969	positive regulation of protein catabolic process
CH55_2472	COG0625	glutathione transferase activity
CH55_2475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH55_2477	COG3105	Protein conserved in bacteria
CH55_2478	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH55_2479	COG1943	Transposase
CH55_2480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH55_2482	COG5007	Belongs to the BolA IbaG family
CH55_2483	COG3113	response to antibiotic
CH55_2484	COG2854	intermembrane phospholipid transfer
CH55_2485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH55_2486	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH55_2487	COG1127	ABC transporter
CH55_2488	COG0530	calcium, potassium:sodium antiporter activity
CH55_2489	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH55_2489	COG0517	IMP dehydrogenase activity
CH55_2490	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH55_2491	COG3117	lipopolysaccharide transmembrane transporter activity
CH55_2492	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH55_2493	COG1137	ATPase activity
CH55_2494	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH55_2496	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_2498	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_2503	COG1609	Transcriptional regulator
CH55_2504	COG1263	PTS System
CH55_2504	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH55_2505	COG0366	Alpha amylase catalytic
CH55_2506	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH55_2507	COG3783	Cytochrome b(562)
CH55_2509	COG0312	modulator of DNA gyrase
CH55_251	COG0840	transmembrane signaling receptor activity
CH55_2511	COG2732	(Barnase) inhibitor
CH55_2514	COG1012	belongs to the aldehyde dehydrogenase family
CH55_2518	COG0583	DNA-binding transcription factor activity
CH55_252	COG0840	transmembrane signaling receptor activity
CH55_2529	COG0312	modulator of DNA gyrase
CH55_253	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH55_2530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH55_2531	COG3164	Protein of unknown function
CH55_2532	COG1530	ribonuclease E activity
CH55_2534	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH55_2535	COG1792	Involved in formation and maintenance of cell shape
CH55_2536	COG1077	Cell shape determining protein MreB Mrl
CH55_2537	COG2199	diguanylate cyclase activity
CH55_2537	COG2200	EAL domain
CH55_2538	COG0604	alcohol dehydrogenase
CH55_2539	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH55_2542	COG0511	ligase activity, forming carbon-carbon bonds
CH55_2543	COG0439	Biotin carboxylase
CH55_2545	COG3924	membrane
CH55_2546	COG4145	pantothenate transmembrane transporter activity
CH55_2548	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH55_2549	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH55_255	COG0745	RESPONSE REGULATOR receiver
CH55_2553	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH55_2555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH55_2556	COG3133	Outer membrane lipoprotein
CH55_2557	COG1278	Cold shock
CH55_2558	COG1278	Cold shock
CH55_2559	COG1943	Transposase
CH55_256	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH55_2562	COG0625	glutathione transferase activity
CH55_2564	COG1069	ribulokinase activity
CH55_2566	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_2567	COG1129	ABC transporter
CH55_2569	COG1560	Kdo2-lipid A biosynthetic process
CH55_257	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH55_2571	COG0025	NhaP-type Na H and K H
CH55_2572	COG2252	PERMEase
CH55_2573	COG3077	Addiction module antitoxin, RelB DinJ family
CH55_2575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH55_2577	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH55_2578	COG0431	NADPH-dependent FMN reductase
CH55_2580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH55_2581	COG1869	D-ribose catabolic process
CH55_2582	COG2207	Transcriptional regulator
CH55_2582	COG1917	Cupin 2, conserved barrel domain protein
CH55_2583	COG0673	inositol 2-dehydrogenase activity
CH55_2586	COG3209	COG3209 Rhs family protein
CH55_2588	COG3501	Rhs element vgr protein
CH55_259	COG5295	Hep Hag repeat protein
CH55_2594	COG3209	COG3209 Rhs family protein
CH55_2597	COG3501	Rhs element vgr protein
CH55_26	COG0586	Pfam SNARE associated Golgi protein
CH55_2612	COG2801	Transposase and inactivated derivatives
CH55_2615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH55_2616	COG0058	SHG alpha-glucan phosphorylase activity
CH55_2619	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CH55_262	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH55_2622	COG3275	phosphorelay sensor kinase activity
CH55_2628	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH55_2629	COG2095	MarC family integral membrane protein
CH55_2633	COG3265	gluconokinase activity
CH55_2634	COG2610	gluconate transmembrane transporter activity
CH55_2635	COG1609	Transcriptional regulator
CH55_2636	COG1741	Belongs to the pirin family
CH55_2638	COG0745	RESPONSE REGULATOR receiver
CH55_2640	COG0191	fructose-bisphosphate aldolase activity
CH55_2642	COG1879	ABC-type sugar transport system periplasmic component
CH55_2643	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_2646	COG2081	HI0933 family
CH55_2647	COG0306	phosphate transporter
CH55_2650	COG0589	response to stress
CH55_2654	COG0339	signal peptide processing
CH55_2655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH55_2656	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH55_2657	COG3835	regulator
CH55_2658	COG2610	gluconate transmembrane transporter activity
CH55_2659	COG1929	Belongs to the glycerate kinase type-1 family
CH55_2664	COG1295	ribonuclease BN
CH55_2665	COG2982	Protein involved in outer membrane biogenesis
CH55_2666	COG2134	cdp-diacylglycerol pyrophosphatase
CH55_2667	COG2982	Protein involved in outer membrane biogenesis
CH55_2668	COG2200	EAL domain
CH55_2669	COG1942	4-Oxalocrotonate Tautomerase
CH55_2670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH55_2671	COG0612	Peptidase, M16
CH55_2675	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH55_2676	COG2200	EAL domain
CH55_2676	COG2199	diguanylate cyclase activity
CH55_2677	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH55_2678	COG4608	Belongs to the ABC transporter superfamily
CH55_2679	COG0444	Belongs to the ABC transporter superfamily
CH55_2680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH55_2681	COG0601	transmembrane transport
CH55_2682	COG0747	negative chemotaxis
CH55_2684	COG2831	hemolysin activation secretion protein
CH55_2686	COG1943	Transposase
CH55_2688	COG2271	Major facilitator Superfamily
CH55_2689	COG3851	Histidine kinase
CH55_2690	COG2197	response regulator
CH55_2691	COG2194	sulfuric ester hydrolase activity
CH55_2694	COG2986	histidine ammonia-lyase
CH55_2697	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH55_2700	COG4607	ABC-type enterochelin transport system periplasmic component
CH55_2702	COG4605	iron ion homeostasis
CH55_2704	COG4604	ABC transporter, ATP-binding protein
CH55_271	COG1012	belongs to the aldehyde dehydrogenase family
CH55_271	COG1454	alcohol dehydrogenase
CH55_2711	COG0582	viral genome integration into host DNA
CH55_2713	COG2207	Transcriptional regulator
CH55_2713	COG1609	Transcriptional regulator
CH55_2714	COG4214	carbohydrate transport
CH55_2716	COG4213	ABC transporter substrate-binding protein
CH55_2718	COG1070	Carbohydrate kinase
CH55_272	COG2095	MarC family integral membrane protein
CH55_2720	COG3121	Chaperone
CH55_2721	COG3188	usher protein
CH55_2722	COG3188	usher protein
CH55_2724	COG3274	enterobacterial common antigen metabolic process
CH55_2726	COG2801	Transposase and inactivated derivatives
CH55_2733	COG3276	selenocysteine insertion sequence binding
CH55_2734	COG3276	selenocysteine insertion sequence binding
CH55_2737	COG2864	formate dehydrogenase
CH55_2738	COG0437	4 iron, 4 sulfur cluster binding
CH55_2739	COG0243	molybdopterin cofactor binding
CH55_2739	COG3383	formate dehydrogenase (NAD+) activity
CH55_274	COG0601	transmembrane transport
CH55_2740	COG3383	formate dehydrogenase (NAD+) activity
CH55_2740	COG0243	molybdopterin cofactor binding
CH55_2742	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH55_2749	COG3722	fumarate hydratase activity
CH55_275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH55_2751	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_2751	COG2213	PTS system mannitol-specific
CH55_2756	COG2818	Glycosylase
CH55_2758	COG2885	chlorophyll binding
CH55_276	COG0444	Belongs to the ABC transporter superfamily
CH55_2761	COG0366	Alpha amylase catalytic
CH55_2763	COG3977	Valine--pyruvate aminotransferase
CH55_2767	COG5645	(Lipo)protein
CH55_2768	COG0823	Involved in the tonB-independent uptake of proteins
CH55_2769	COG0823	Involved in the tonB-independent uptake of proteins
CH55_277	COG4608	Belongs to the ABC transporter superfamily
CH55_2770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH55_2771	COG2423	ornithine cyclodeaminase activity
CH55_2774	COG2801	Transposase and inactivated derivatives
CH55_2775	COG0561	phosphatase activity
CH55_2776	COG0187	DNA topoisomerase II activity
CH55_2777	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH55_2778	COG0592	DNA-directed DNA polymerase activity
CH55_2781	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH55_2784	COG0706	membrane insertase activity
CH55_2789	COG2252	PERMEase
CH55_2790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH55_2791	COG0765	amino acid transport
CH55_2792	COG0765	amino acid transport
CH55_2793	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH55_2795	COG0704	Plays a role in the regulation of phosphate uptake
CH55_2797	COG0581	inorganic phosphate transmembrane transporter activity
CH55_2798	COG0573	inorganic phosphate transmembrane transporter activity
CH55_2799	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH55_28	COG0285	dihydrofolate synthase activity
CH55_2800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH55_2810	COG3312	ion transport
CH55_2813	COG0716	FMN binding
CH55_2814	COG1522	sequence-specific DNA binding
CH55_2820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH55_2821	COG0477	Major facilitator Superfamily
CH55_2823	COG2186	Transcriptional regulator
CH55_2833	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH55_2834	COG2224	Isocitrate lyase
CH55_2836	COG1414	Transcriptional regulator
CH55_2837	COG1414	Transcriptional regulator
CH55_284	COG2350	Protein conserved in bacteria
CH55_2841	COG0527	aspartate kinase activity
CH55_2844	COG3833	ABC-type maltose transport systems, permease component
CH55_2845	COG1175	transmembrane transport
CH55_286	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH55_2860	COG2801	Transposase and inactivated derivatives
CH55_2863	COG1349	DNA-binding transcription factor activity
CH55_2867	COG0058	SHG alpha-glucan phosphorylase activity
CH55_2868	COG0058	SHG alpha-glucan phosphorylase activity
CH55_2869	COG1640	4-alpha-glucanotransferase
CH55_287	COG3328	transposase activity
CH55_2876	COG1918	ferrous iron import across plasma membrane
CH55_2877	COG2183	response to ionizing radiation
CH55_2878	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH55_2879	COG0745	RESPONSE REGULATOR receiver
CH55_288	COG1607	acyl-coa hydrolase
CH55_2883	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH55_2884	COG1011	Hydrolase
CH55_2887	COG0494	nUDIX hydrolase
CH55_2888	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH55_2893	COG4796	Type ii and iii secretion system protein
CH55_2898	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH55_2899	COG0546	phosphoglycolate phosphatase activity
CH55_29	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH55_2900	COG0180	Tryptophanyl-tRNA synthetase
CH55_2903	COG2146	nitrite reductase [NAD(P)H] activity
CH55_2904	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH55_2905	COG0402	S-adenosylhomocysteine deaminase activity
CH55_2909	COG1486	melibiose metabolic process
CH55_2910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH55_2911	COG0433	COG0433 Predicted ATPase
CH55_2914	COG1289	transmembrane transporter activity
CH55_2916	COG1765	OsmC-like protein
CH55_2918	COG3954	Phosphoribulokinase
CH55_2920	COG0429	hydrolase of the alpha beta-hydrolase fold
CH55_2922	COG4521	taurine ABC transporter
CH55_2924	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH55_2925	COG2175	clavaminate synthase activity
CH55_2927	COG1216	Glycosyl transferase, family 2
CH55_2928	COG0488	(ABC) transporter
CH55_2929	COG0488	(ABC) transporter
CH55_293	COG3047	cAMP biosynthetic process
CH55_2932	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH55_2933	COG1047	Peptidyl-prolyl cis-trans
CH55_2935	COG0545	Peptidyl-prolyl cis-trans isomerase
CH55_2936	COG2964	Protein conserved in bacteria
CH55_2940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH55_2941	COG0049	tRNA binding
CH55_2944	COG1943	Transposase
CH55_2947	COG0051	transcription antitermination factor activity, RNA binding
CH55_2952	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH55_2954	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH55_2955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH55_2957	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH55_2958	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH55_2966	COG1841	ribosomal large subunit assembly
CH55_2968	COG0201	protein transport
CH55_2969	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH55_297	COG0135	phosphoribosylanthranilate isomerase activity
CH55_297	COG0134	indole-3-glycerol-phosphate synthase activity
CH55_2972	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH55_2975	COG0789	Transcriptional regulator
CH55_2976	COG3036	rescue of stalled ribosome
CH55_2978	COG0569	domain protein
CH55_2982	COG0758	DNA mediated transformation
CH55_2984	COG0551	DNA topoisomerase type I activity
CH55_2987	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH55_299	COG0512	Glutamine amidotransferase of anthranilate synthase
CH55_2992	COG0456	acetyltransferase
CH55_2993	COG2982	Protein involved in outer membrane biogenesis
CH55_2994	COG2233	PERMEase
CH55_2995	COG0786	glutamate:sodium symporter activity
CH55_2996	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH55_2997	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH55_2998	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH55_30	COG1286	toxin biosynthetic process
CH55_3001	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH55_3003	COG2860	membrane
CH55_3004	COG1561	YicC-like family, N-terminal region
CH55_3009	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH55_3012	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH55_3016	COG1519	Transferase
CH55_3017	COG0859	PFAM glycosyl transferase family 9
CH55_3018	COG0859	PFAM glycosyl transferase family 9
CH55_302	COG0009	L-threonylcarbamoyladenylate synthase
CH55_3020	COG0156	8-amino-7-oxononanoate synthase activity
CH55_3022	COG2861	carbohydrate metabolic process
CH55_3023	COG2861	carbohydrate metabolic process
CH55_3024	COG4942	peptidase
CH55_3026	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH55_3027	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH55_303	COG1187	pseudouridine synthase activity
CH55_3030	COG1045	serine acetyltransferase
CH55_3031	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH55_3032	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH55_3032	COG2169	Transcriptional regulator
CH55_3033	COG2205	protein histidine kinase activity
CH55_3034	COG0745	RESPONSE REGULATOR receiver
CH55_3035	COG3678	ATP-independent chaperone mediated protein folding
CH55_3040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH55_3042	COG0471	metal ion transport
CH55_3043	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH55_3044	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH55_3045	COG0583	DNA-binding transcription factor activity
CH55_3048	COG3152	Membrane
CH55_305	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_3050	COG1494	fructose-1,6-bisphosphatase
CH55_3051	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH55_3052	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH55_3054	COG1943	Transposase
CH55_306	COG0616	signal peptide processing
CH55_3060	COG1575	Belongs to the MenA family. Type 1 subfamily
CH55_3063	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH55_3064	COG1609	Transcriptional regulator
CH55_3066	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH55_3068	COG4682	membrane
CH55_3070	COG0626	cystathionine gamma-synthase activity
CH55_3071	COG0626	cystathionine gamma-synthase activity
CH55_3072	COG0460	homoserine dehydrogenase
CH55_3072	COG0527	aspartate kinase activity
CH55_3074	COG2801	Transposase and inactivated derivatives
CH55_3078	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH55_3082	COG1629	transport
CH55_3088	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH55_3089	COG0678	peroxiredoxin activity
CH55_3089	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH55_309	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH55_31	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH55_310	COG0583	DNA-binding transcription factor activity
CH55_3104	COG1879	ABC-type sugar transport system periplasmic component
CH55_3105	COG1129	ABC transporter
CH55_3106	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_3108	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_3109	COG3085	chromosome segregation
CH55_3112	COG3978	acetolactate synthase activity
CH55_3113	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH55_312	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH55_3122	COG0583	DNA-binding transcription factor activity
CH55_3129	COG3121	Chaperone
CH55_313	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH55_3133	COG3121	Chaperone
CH55_3135	COG3328	transposase activity
CH55_3137	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH55_314	COG0671	phosphoesterase, PA-phosphatase related
CH55_3142	COG3118	belongs to the thioredoxin family
CH55_3143	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH55_3144	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH55_3145	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH55_3146	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH55_3147	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH55_3148	COG1088	dTDP-glucose 4,6-dehydratase activity
CH55_3149	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH55_315	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH55_3150	COG0456	acetyltransferase
CH55_3151	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH55_3152	COG2244	polysaccharide biosynthetic process
CH55_3156	COG1113	amino acid transport
CH55_316	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH55_3162	COG1943	Transposase
CH55_3163	COG3071	HemY protein
CH55_3164	COG2959	enzyme of heme biosynthesis
CH55_3165	COG1587	Uroporphyrinogen-III synthase
CH55_3167	COG3072	Adenylate cyclase
CH55_3169	COG5567	small periplasmic lipoprotein
CH55_3171	COG3159	Protein conserved in bacteria
CH55_3172	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH55_3173	COG1011	Hydrolase
CH55_3174	COG0210	DNA helicase
CH55_3176	COG5441	Belongs to the UPF0261 family
CH55_3177	COG5564	TIM-barrel signal transduction protein
CH55_3178	COG0598	Magnesium transport protein CorA
CH55_3180	COG2050	protein possibly involved in aromatic compounds catabolism
CH55_3181	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH55_3182	COG0514	ATP-dependent DNA helicase (RecQ)
CH55_3183	COG1280	lysine exporter protein (LysE YggA)
CH55_3184	COG1280	lysine exporter protein (LysE YggA)
CH55_3185	COG2267	carboxylic ester hydrolase activity
CH55_3186	COG0561	phosphatase activity
CH55_3188	COG0584	glycerophosphoryl diester phosphodiesterase
CH55_3189	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH55_319	COG0023	Translation Initiation Factor
CH55_3191	COG0247	lactate metabolic process
CH55_3193	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH55_3196	COG3714	YhhN family
CH55_3199	COG3776	membrane
CH55_32	COG0163	prenyltransferase activity
CH55_3200	COG0742	ribosomal rna small subunit methyltransferase
CH55_3201	COG0552	protein localization to endoplasmic reticulum
CH55_3201	COG0552	protein localization to endoplasmic reticulum
CH55_3202	COG2884	Cell division ATP-binding protein ftsE
CH55_3203	COG2177	Part of the ABC transporter FtsEX involved in
CH55_3205	COG1943	Transposase
CH55_3207	COG0683	leucine binding
CH55_3208	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH55_3209	COG4177	L-phenylalanine transmembrane transporter activity
CH55_3210	COG0411	ABC transporter
CH55_3211	COG0410	ABC transporter
CH55_3224	COG0584	glycerophosphoryl diester phosphodiesterase
CH55_3225	COG0679	Auxin Efflux Carrier
CH55_3226	COG0583	DNA-binding transcription factor activity
CH55_3229	COG0412	Dienelactone hydrolase
CH55_323	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH55_3230	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CH55_3232	COG1966	Carbon starvation protein
CH55_3233	COG0586	Pfam SNARE associated Golgi protein
CH55_3234	COG1322	Protein conserved in bacteria
CH55_3238	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH55_324	COG2879	small protein
CH55_3240	COG0805	protein transport
CH55_325	COG1966	Carbon starvation protein
CH55_3252	COG1739	Uncharacterized protein family UPF0029
CH55_3253	COG1943	Transposase
CH55_3254	COG1739	Uncharacterized protein family UPF0029
CH55_3255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH55_3256	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH55_3261	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH55_327	COG2271	Major facilitator Superfamily
CH55_3273	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH55_3274	COG0250	Participates in transcription elongation, termination and antitermination
CH55_328	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH55_3286	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH55_3288	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH55_329	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH55_3293	COG1515	deoxyribonuclease V activity
CH55_3294	COG3068	Protein conserved in bacteria
CH55_3297	COG0151	Belongs to the GarS family
CH55_33	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH55_3305	COG2801	Transposase and inactivated derivatives
CH55_331	COG4659	FMN binding
CH55_3311	COG4771	TonB-dependent receptor
CH55_3312	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH55_3313	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH55_332	COG4658	electron transport chain
CH55_3321	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH55_3324	COG5001	Diguanylate cyclase
CH55_3324	COG3300	MHYT domain
CH55_3325	COG2801	Transposase and inactivated derivatives
CH55_333	COG3708	Transcriptional regulator
CH55_333	COG2207	Transcriptional regulator
CH55_3331	COG0195	Participates in both transcription termination and antitermination
CH55_3335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH55_3337	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH55_3338	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH55_3340	COG1534	Rna-binding protein
CH55_3341	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH55_3342	COG2027	D-alanyl-D-alanine carboxypeptidase
CH55_3343	COG0745	RESPONSE REGULATOR receiver
CH55_3344	COG0642	Histidine kinase
CH55_3346	COG0697	spore germination
CH55_3349	COG0142	geranyltranstransferase activity
CH55_3351	COG3423	Transcriptional regulator
CH55_3355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH55_3357	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH55_3358	COG2105	PFAM AIG2 family protein
CH55_3359	COG2911	Protein conserved in bacteria
CH55_3360	COG2911	Protein conserved in bacteria
CH55_3361	COG0729	surface antigen
CH55_3363	COG1253	flavin adenine dinucleotide binding
CH55_3365	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH55_3367	COG0737	Belongs to the 5'-nucleotidase family
CH55_3369	COG0545	Peptidyl-prolyl cis-trans isomerase
CH55_3370	COG3061	Opacity-associated protein A
CH55_3372	COG1943	Transposase
CH55_3374	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH55_3375	COG0360	Binds together with S18 to 16S ribosomal RNA
CH55_3377	COG1073	alpha beta
CH55_3380	COG3650	response to hydrogen peroxide
CH55_3381	COG1960	acyl-CoA dehydrogenase activity
CH55_3382	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH55_3383	COG0557	exoribonuclease II activity
CH55_3386	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH55_3387	COG0330	HflC and HflK could
CH55_3388	COG0330	HflC and HflK could
CH55_3389	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH55_3393	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH55_3394	COG0802	atpase or kinase
CH55_3395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH55_3395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH55_3396	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH55_34	COG4215	(ABC) transporter
CH55_340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH55_3400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH55_3403	COG3264	Mechanosensitive ion channel
CH55_3403	COG1511	domain protein
CH55_3405	COG1053	succinate dehydrogenase
CH55_3406	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH55_3408	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH55_3409	COG2076	Multidrug Resistance protein
CH55_341	COG2274	protein secretion by the type I secretion system
CH55_3417	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH55_3420	COG3383	formate dehydrogenase (NAD+) activity
CH55_3421	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH55_3422	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH55_3422	COG0493	'glutamate synthase
CH55_3423	COG1309	transcriptional regulator
CH55_3437	COG1454	alcohol dehydrogenase
CH55_3439	COG0629	single-stranded DNA binding
CH55_3440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH55_3441	COG2315	Protein conserved in bacteria
CH55_3442	COG1448	Aminotransferase
CH55_3443	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH55_3444	COG0305	Participates in initiation and elongation during chromosome replication
CH55_3447	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH55_3448	COG0735	belongs to the Fur family
CH55_345	COG1879	ABC-type sugar transport system periplasmic component
CH55_3450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH55_3458	COG3121	Chaperone
CH55_347	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_3470	COG1358	cellular component organization or biogenesis
CH55_3475	COG3721	Heme iron utilization protein
CH55_3476	COG0702	epimerase
CH55_3477	COG4771	TonB-dependent receptor
CH55_3478	COG3720	iron ion transport
CH55_3479	COG4558	Periplasmic binding protein
CH55_3480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH55_3482	COG0626	cystathionine gamma-synthase activity
CH55_3483	COG0814	amino acid
CH55_3484	COG0583	DNA-binding transcription factor activity
CH55_3485	COG0425	Belongs to the sulfur carrier protein TusA family
CH55_3486	COG2391	methyltransferase activity
CH55_349	COG0673	inositol 2-dehydrogenase activity
CH55_35	COG4160	amino acid transport
CH55_350	COG0385	Bile acid
CH55_3509	COG1301	dicarboxylic acid transport
CH55_3511	COG3162	membrane
CH55_3516	COG3433	isochorismatase activity
CH55_3516	COG2226	methyltransferase
CH55_3516	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH55_3517	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH55_3517	COG3433	isochorismatase activity
CH55_3517	COG2226	methyltransferase
CH55_3519	COG3433	isochorismatase activity
CH55_3519	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH55_3519	COG2226	methyltransferase
CH55_352	COG5339	Protein conserved in bacteria
CH55_3520	COG3433	isochorismatase activity
CH55_3520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH55_3520	COG2226	methyltransferase
CH55_3527	COG1132	(ABC) transporter
CH55_3531	COG2610	gluconate transmembrane transporter activity
CH55_3535	COG3501	Rhs element vgr protein
CH55_3537	COG3209	COG3209 Rhs family protein
CH55_354	COG0114	fumarate hydratase activity
CH55_3540	COG0471	metal ion transport
CH55_3542	COG2801	Transposase and inactivated derivatives
CH55_3545	COG2211	Major facilitator Superfamily
CH55_3555	COG3916	Acyl-homoserine-lactone synthase
CH55_3556	COG2771	luxR family
CH55_356	COG2814	Major facilitator Superfamily
CH55_357	COG0583	DNA-binding transcription factor activity
CH55_3577	COG1662	PFAM IS1 transposase
CH55_358	COG1940	carbohydrate kinase activity
CH55_3581	COG1982	Orn Lys Arg decarboxylase major
CH55_3582	COG1879	ABC-type sugar transport system periplasmic component
CH55_3583	COG1129	ABC transporter
CH55_3584	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_3585	COG4774	siderophore transport
CH55_3589	COG1194	a g-specific adenine glycosylase
CH55_3591	COG3171	Protein conserved in bacteria
CH55_3592	COG2066	Belongs to the glutaminase family
CH55_3595	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH55_3595	COG1073	alpha beta
CH55_3595	COG3064	Membrane
CH55_3596	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH55_3597	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH55_3599	COG0762	integral membrane protein
CH55_36	COG4598	ABC transporter
CH55_360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH55_3600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH55_3601	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH55_3602	COG2805	Type II/IV secretion system protein
CH55_3604	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH55_3607	COG0189	ligase activity
CH55_3608	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH55_3609	COG2356	endonuclease I
CH55_361	COG0038	chloride channel
CH55_3613	COG1166	arginine decarboxylase activity
CH55_3615	COG0501	Belongs to the peptidase M48B family
CH55_3616	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH55_3617	COG1943	Transposase
CH55_362	COG1609	Transcriptional regulator
CH55_3620	COG0191	fructose-bisphosphate aldolase activity
CH55_3625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH55_3626	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH55_3627	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH55_3630	COG0006	proline dipeptidase activity
CH55_3631	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH55_3632	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH55_3638	COG5295	Hep Hag repeat protein
CH55_364	COG1879	ABC-type sugar transport system periplasmic component
CH55_3640	COG1272	protein, Hemolysin III
CH55_3643	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH55_3644	COG0745	RESPONSE REGULATOR receiver
CH55_3645	COG2205	protein histidine kinase activity
CH55_3646	COG4452	Inner membrane protein CreD
CH55_3647	COG0716	FMN binding
CH55_3648	COG4974	Belongs to the 'phage' integrase family
CH55_3649	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH55_365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH55_3650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH55_3654	COG0582	viral genome integration into host DNA
CH55_3659	COG2944	sequence-specific DNA binding
CH55_366	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH55_3676	COG1695	Transcriptional regulator
CH55_3677	COG0791	NLP P60 protein
CH55_3679	COG1879	ABC-type sugar transport system periplasmic component
CH55_368	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH55_3680	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_3681	COG1129	ABC transporter
CH55_3683	COG2182	Extracellular solute-binding protein
CH55_3684	COG1175	transmembrane transport
CH55_3685	COG3833	ABC-type maltose transport systems, permease component
CH55_3688	COG1874	Beta-galactosidase
CH55_3689	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH55_3689	COG1263	PTS System
CH55_3693	COG2271	Major facilitator Superfamily
CH55_3697	COG0191	fructose-bisphosphate aldolase activity
CH55_3699	COG3119	arylsulfatase activity
CH55_37	COG1090	epimerase
CH55_3700	COG0641	radical SAM
CH55_3702	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_3703	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_3705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_3706	COG3716	PTS system mannose fructose sorbose family IID component
CH55_3707	COG3715	PTS system
CH55_3708	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH55_3709	COG2222	sugar isomerase
CH55_3711	COG1349	DNA-binding transcription factor activity
CH55_3712	COG3119	arylsulfatase activity
CH55_3721	COG0288	reversible hydration of carbon dioxide
CH55_374	COG0028	Belongs to the TPP enzyme family
CH55_3740	COG0840	transmembrane signaling receptor activity
CH55_3742	COG0583	DNA-binding transcription factor activity
CH55_3743	COG0583	DNA-binding transcription factor activity
CH55_3744	COG2814	Major facilitator Superfamily
CH55_3745	COG1609	Transcriptional regulator
CH55_3746	COG0019	diaminopimelate decarboxylase activity
CH55_375	COG0440	acetolactate synthase activity
CH55_3753	COG0667	Aldo Keto reductase
CH55_376	COG1011	Hydrolase
CH55_3765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH55_3767	COG1074	ATP-dependent DNA helicase activity
CH55_3768	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH55_3770	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH55_3773	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH55_3774	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH55_3775	COG2166	iron-sulfur cluster assembly
CH55_3776	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH55_3778	COG0583	DNA-binding transcription factor activity
CH55_3779	COG2363	Small membrane protein
CH55_3781	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH55_3782	COG1611	Belongs to the LOG family
CH55_3785	COG1943	Transposase
CH55_3786	COG3098	single-species biofilm formation
CH55_3787	COG0564	pseudouridine synthase activity
CH55_379	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH55_3790	COG1943	Transposase
CH55_3793	COG0024	Methionine aminopeptidase
CH55_3799	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH55_380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH55_3800	COG0575	Belongs to the CDS family
CH55_3801	COG0750	zinc metalloprotease
CH55_3803	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH55_3807	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH55_3809	COG0587	DNA-directed DNA polymerase activity
CH55_381	COG0589	response to stress
CH55_3811	COG0346	lactoylglutathione lyase activity
CH55_3812	COG0037	tRNA processing
CH55_3814	COG4568	rho-dependent transcription termination
CH55_3816	COG4681	YaeQ
CH55_3818	COG3015	lipoprotein NlpE involved in copper resistance
CH55_382	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH55_3820	COG1720	tRNA m6t6A37 methyltransferase activity
CH55_3822	COG1464	Belongs to the NlpA lipoprotein family
CH55_3823	COG2011	ABC-type metal ion transport system permease component
CH55_3825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH55_383	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH55_3831	COG0656	L-ascorbic acid biosynthetic process
CH55_3834	COG1388	LysM domain
CH55_3834	COG0741	lytic transglycosylase activity
CH55_3836	COG2226	methyltransferase
CH55_3838	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH55_3840	COG1953	Uracil, thiamine, allantoin
CH55_3846	COG3657	addiction module killer protein
CH55_385	COG0531	amino acid
CH55_3856	COG0582	viral genome integration into host DNA
CH55_3857	COG1943	Transposase
CH55_3859	COG2867	negative regulation of translational initiation
CH55_3861	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH55_3862	COG0497	DNA recombination
CH55_3863	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH55_3866	COG2009	succinate dehydrogenase
CH55_3867	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH55_3868	COG1053	succinate dehydrogenase
CH55_387	COG0745	RESPONSE REGULATOR receiver
CH55_3870	COG0567	Dehydrogenase, E1 component
CH55_3871	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH55_3873	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH55_3874	COG1271	oxidase subunit
CH55_3875	COG1294	oxidase, subunit
CH55_3876	COG4890	Cyd operon protein YbgT
CH55_3877	COG3790	cyd operon protein YbgE
CH55_3878	COG0824	Thioesterase
CH55_3879	COG0811	peptide transport
CH55_388	COG2205	protein histidine kinase activity
CH55_3880	COG0848	biopolymer transport protein
CH55_3881	COG3064	Membrane
CH55_3881	COG3064	Membrane
CH55_3883	COG2885	chlorophyll binding
CH55_3884	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH55_389	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH55_3890	COG1230	cation diffusion facilitator family transporter
CH55_3892	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH55_3895	COG2017	converts alpha-aldose to the beta-anomer
CH55_3898	COG1085	galactose-1-phosphate uridylyltransferase
CH55_3899	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH55_39	COG0622	Phosphoesterase
CH55_390	COG1943	Transposase
CH55_3902	COG1119	ATPase activity
CH55_3903	COG2005	Transcriptional regulator
CH55_3903	COG3585	molybdate ion transport
CH55_3905	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH55_3906	COG4149	molybdate abc transporter
CH55_3908	COG0561	phosphatase activity
CH55_3913	COG2226	methyltransferase
CH55_3914	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH55_3916	COG0556	nucleotide-excision repair
CH55_3917	COG4628	conserved protein (DUF2132)
CH55_3918	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH55_3920	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH55_3922	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH55_3923	COG0314	molybdopterin synthase activity
CH55_3924	COG0670	Belongs to the BI1 family
CH55_3925	COG1943	Transposase
CH55_3929	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH55_393	COG3038	cytochrome b561
CH55_3930	COG0583	DNA-binding transcription factor activity
CH55_3932	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH55_3933	COG2211	Major facilitator Superfamily
CH55_3934	COG1943	Transposase
CH55_3935	COG2211	Major facilitator Superfamily
CH55_3939	COG1902	pentaerythritol trinitrate reductase activity
CH55_3942	COG0842	Transport permease protein
CH55_3943	COG0842	Transport permease protein
CH55_3944	COG1131	(ABC) transporter
CH55_3946	COG1309	transcriptional regulator
CH55_3947	COG0513	Belongs to the DEAD box helicase family
CH55_395	COG3591	Belongs to the peptidase S1B family
CH55_3955	COG3328	transposase activity
CH55_3956	COG3328	transposase activity
CH55_3959	COG0351	phosphomethylpyrimidine kinase
CH55_3966	COG3422	double-strand break repair
CH55_3967	COG0745	RESPONSE REGULATOR receiver
CH55_3968	COG2205	protein histidine kinase activity
CH55_3973	COG3842	ATPase activity
CH55_3975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH55_3977	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH55_3978	COG1177	transmembrane transport
CH55_3979	COG0443	Heat shock 70 kDa protein
CH55_398	COG1643	Atp-dependent helicase
CH55_3980	COG2239	Acts as a magnesium transporter
CH55_3981	COG2239	Acts as a magnesium transporter
CH55_3982	COG0248	Ppx GppA phosphatase
CH55_3983	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH55_3986	COG0581	inorganic phosphate transmembrane transporter activity
CH55_3991	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH55_3992	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH55_3995	COG1943	Transposase
CH55_3997	COG1393	Belongs to the ArsC family
CH55_3998	COG4783	chaperone-mediated protein folding
CH55_3999	COG0628	permease
CH55_40	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH55_400	COG2390	Transcriptional regulator
CH55_4002	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH55_4003	COG2716	regulation of RNA biosynthetic process
CH55_4005	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH55_4006	COG1943	Transposase
CH55_4009	COG2321	neutral zinc metallopeptidase
CH55_401	COG0246	Mannitol dehydrogenase
CH55_4010	COG2321	neutral zinc metallopeptidase
CH55_4014	COG1876	peptidase activity
CH55_4016	COG1393	Belongs to the ArsC family
CH55_4018	COG1840	ABC-type Fe3 transport system, periplasmic component
CH55_4019	COG1175	transmembrane transport
CH55_402	COG3784	Protein of unknown function (DUF1318)
CH55_4020	COG3842	ATPase activity
CH55_4021	COG3119	arylsulfatase activity
CH55_4022	COG0641	radical SAM
CH55_4023	COG1988	membrane-bound metal-dependent
CH55_4025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH55_4026	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH55_4027	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH55_4029	COG2197	response regulator
CH55_4030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH55_4030	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH55_4031	COG3062	negative regulation of establishment of protein localization
CH55_4033	COG3043	anaerobic respiration
CH55_4034	COG3005	denitrification pathway
CH55_404	COG2911	Protein conserved in bacteria
CH55_4043	COG3111	PFAM Bacterial OB fold (BOF) protein
CH55_4046	COG2837	iron assimilation
CH55_4047	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH55_4049	COG4886	Leucine-rich repeat (LRR) protein
CH55_405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH55_4051	COG2731	YhcH YjgK YiaL family protein
CH55_4052	COG1737	Transcriptional regulator
CH55_4054	COG4150	thiosulfate binding
CH55_4055	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH55_4056	COG4208	sulfate ABC transporter
CH55_4057	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH55_406	COG3187	Heat shock protein
CH55_4060	COG0745	RESPONSE REGULATOR receiver
CH55_4061	COG5002	protein histidine kinase activity
CH55_4061	COG3850	Histidine kinase
CH55_4063	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH55_4065	COG0006	proline dipeptidase activity
CH55_4067	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH55_4070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH55_4071	COG0745	RESPONSE REGULATOR receiver
CH55_4072	COG2205	protein histidine kinase activity
CH55_4077	COG1943	Transposase
CH55_4078	COG2190	(PTS) system
CH55_408	COG1285	pathogenesis
CH55_4080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_4081	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH55_4082	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH55_4085	COG3530	Putative quorum-sensing-regulated virulence factor
CH55_4091	COG1943	Transposase
CH55_4096	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH55_4099	COG0667	Aldo Keto reductase
CH55_41	COG3037	sugar-specific permease SgaT UlaA
CH55_410	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH55_410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH55_410	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH55_410	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH55_4104	COG0436	Aminotransferase
CH55_4105	COG3038	cytochrome b561
CH55_4111	COG3381	protein complex oligomerization
CH55_4112	COG3302	dmso reductase anchor subunit
CH55_4113	COG0437	4 iron, 4 sulfur cluster binding
CH55_4114	COG0243	molybdopterin cofactor binding
CH55_4122	COG2951	lytic endotransglycosylase activity
CH55_413	COG2755	lipolytic protein G-D-S-L family
CH55_413	COG0657	acetylesterase activity
CH55_4134	COG3121	Chaperone
CH55_4135	COG3188	usher protein
CH55_4136	COG3328	transposase activity
CH55_4137	COG3328	transposase activity
CH55_4138	COG3188	usher protein
CH55_4151	COG3501	Rhs element vgr protein
CH55_4157	COG2824	Alkylphosphonate utilization operon protein PhnA
CH55_4159	COG1704	LemA family
CH55_416	COG4166	transmembrane transport
CH55_4163	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH55_4164	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH55_4165	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH55_4167	COG1138	Cytochrome C-type biogenesis protein
CH55_417	COG2866	Carboxypeptidase
CH55_4174	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH55_4176	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH55_418	COG4948	Mandelate Racemase Muconate Lactonizing
CH55_4188	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH55_419	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH55_42	COG3328	transposase activity
CH55_420	COG1943	Transposase
CH55_4201	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH55_4202	COG1475	DNA binding
CH55_4203	COG1475	DNA binding
CH55_4223	COG3941	tape measure
CH55_4230	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH55_4230	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH55_4232	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH55_4239	COG3328	transposase activity
CH55_4241	COG3344	reverse transcriptase
CH55_4243	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH55_425	COG3106	COG3106 Predicted ATPase
CH55_4259	COG1475	DNA binding
CH55_427	COG1983	PspC domain protein
CH55_4282	COG2207	Transcriptional regulator
CH55_4283	COG2207	Transcriptional regulator
CH55_4285	COG4792	protein secretion
CH55_4286	COG4791	protein targeting
CH55_4287	COG4794	Type iii secretion
CH55_4288	COG4790	Type iii secretion
CH55_4289	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH55_429	COG1842	Phage shock protein A
CH55_4299	COG4789	Type iii secretion
CH55_430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH55_4303	COG0457	Tetratricopeptide repeat
CH55_4308	COG4886	Leucine-rich repeat (LRR) protein
CH55_431	COG4166	transmembrane transport
CH55_4313	COG3177	Filamentation induced by cAMP protein fic
CH55_4317	COG2801	Transposase and inactivated derivatives
CH55_432	COG4168	peptide transport system, permease
CH55_4320	COG1192	Involved in chromosome partitioning
CH55_4321	COG1475	DNA binding
CH55_4323	COG3609	addiction module antidote protein, CC2985 family
CH55_4325	COG5599	Phosphatase
CH55_4327	COG2801	Transposase and inactivated derivatives
CH55_433	COG4171	peptide transport system, permease
CH55_4331	COG2801	Transposase and inactivated derivatives
CH55_4337	COG2801	Transposase and inactivated derivatives
CH55_435	COG4172	Belongs to the ABC transporter superfamily
CH55_4357	COG0515	serine threonine protein kinase
CH55_4358	COG0515	serine threonine protein kinase
CH55_436	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH55_436	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH55_4360	COG2801	Transposase and inactivated derivatives
CH55_4363	COG2801	Transposase and inactivated derivatives
CH55_4364	COG2963	transposase activity
CH55_4365	COG5599	Phosphatase
CH55_4366	COG1317	bacterial-type flagellum organization
CH55_4368	COG4669	(LipO)protein
CH55_4379	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CH55_438	COG3104	oligopeptide transport
CH55_441	COG0625	glutathione transferase activity
CH55_445	COG3895	Periplasmic Protein
CH55_447	COG3133	Outer membrane lipoprotein
CH55_449	COG2194	sulfuric ester hydrolase activity
CH55_45	COG1609	Transcriptional regulator
CH55_450	COG1309	transcriptional regulator
CH55_451	COG1902	pentaerythritol trinitrate reductase activity
CH55_453	COG0346	lactoylglutathione lyase activity
CH55_454	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH55_455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH55_457	COG0791	NLP P60 protein
CH55_458	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH55_46	COG0857	belongs to the CobB CobQ family
CH55_46	COG0280	phosphate acetyltransferase
CH55_460	COG0583	DNA-binding transcription factor activity
CH55_461	COG1609	Transcriptional regulator
CH55_462	COG2814	Major facilitator Superfamily
CH55_463	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH55_464	COG0307	riboflavin synthase, alpha
CH55_469	COG4238	major outer membrane lipoprotein
CH55_474	COG1388	LysM domain
CH55_474	COG1376	ErfK ybiS ycfS ynhG family protein
CH55_477	COG0719	Fe-S assembly protein
CH55_478	COG0396	ATPase activity
CH55_479	COG0719	Fe-S assembly protein
CH55_480	COG0316	Belongs to the HesB IscA family
CH55_481	COG2050	protein possibly involved in aromatic compounds catabolism
CH55_482	COG0277	FAD linked oxidase domain protein
CH55_482	COG0247	lactate metabolic process
CH55_483	COG0628	permease
CH55_484	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH55_484	COG0574	Belongs to the PEP-utilizing enzyme family
CH55_485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH55_485	COG0574	Belongs to the PEP-utilizing enzyme family
CH55_491	COG0791	NLP P60 protein
CH55_499	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CH55_5	COG3691	Protein conserved in bacteria
CH55_50	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH55_500	COG0386	Belongs to the glutathione peroxidase family
CH55_503	COG0776	regulation of translation
CH55_504	COG0072	phenylalanine-tRNA ligase activity
CH55_504	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH55_505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH55_51	COG0490	domain, Protein
CH55_51	COG0471	metal ion transport
CH55_510	COG4249	Peptidase C14 caspase catalytic subunit p20
CH55_514	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH55_515	COG1121	(ABC) transporter
CH55_516	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH55_517	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH55_520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH55_521	COG3328	transposase activity
CH55_522	COG1917	Cupin 2, conserved barrel domain protein
CH55_524	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_526	COG1175	transmembrane transport
CH55_527	COG0395	ABC-type sugar transport system, permease component
CH55_528	COG3842	ATPase activity
CH55_529	COG1653	transport
CH55_53	COG0436	Aminotransferase
CH55_530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH55_531	COG1988	membrane-bound metal-dependent
CH55_533	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH55_535	COG0823	Involved in the tonB-independent uptake of proteins
CH55_536	COG2814	Major facilitator Superfamily
CH55_537	COG3121	Chaperone
CH55_54	COG0583	DNA-binding transcription factor activity
CH55_540	COG3121	Chaperone
CH55_541	COG3539	Fimbrial protein
CH55_544	COG0793	Belongs to the peptidase S41A family
CH55_546	COG1956	GAF domain-containing protein
CH55_547	COG2995	paraquat-inducible protein a
CH55_548	COG3008	intermembrane lipid transfer
CH55_549	COG3008	intermembrane lipid transfer
CH55_553	COG3121	Chaperone
CH55_56	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH55_560	COG1435	thymidine kinase activity
CH55_563	COG0745	RESPONSE REGULATOR receiver
CH55_565	COG3328	transposase activity
CH55_566	COG0788	formyltetrahydrofolate deformylase activity
CH55_569	COG0583	DNA-binding transcription factor activity
CH55_570	COG0708	Exodeoxyribonuclease III
CH55_571	COG0494	nUDIX hydrolase
CH55_573	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH55_574	COG0709	Synthesizes selenophosphate from selenide and ATP
CH55_575	COG0778	Nitroreductase
CH55_576	COG0616	signal peptide processing
CH55_577	COG0252	asparaginase activity
CH55_578	COG1335	isochorismatase
CH55_579	COG3139	Protein of unknown function (DUF1315)
CH55_58	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CH55_583	COG3713	MltA-interacting MipA family protein
CH55_584	COG2766	serine protein kinase
CH55_587	COG0583	DNA-binding transcription factor activity
CH55_589	COG2814	Major facilitator Superfamily
CH55_591	COG2719	SpoVR family
CH55_597	COG1104	cysteine desulfurase activity
CH55_599	COG3328	transposase activity
CH55_60	COG1034	ATP synthesis coupled electron transport
CH55_63	COG0839	Belongs to the complex I subunit 6 family
CH55_631	COG3328	transposase activity
CH55_65	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH55_651	COG0582	viral genome integration into host DNA
CH55_653	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH55_654	COG2951	lytic endotransglycosylase activity
CH55_658	COG2894	cell division
CH55_659	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH55_66	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH55_660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH55_661	COG0318	PFAM AMP-dependent synthetase and ligase
CH55_662	COG3065	identical protein binding
CH55_664	COG1199	ATP-dependent helicase activity
CH55_665	COG0251	oxidation-reduction process
CH55_668	COG0800	Aldolase
CH55_670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH55_671	COG1737	Transcriptional regulator
CH55_672	COG0469	pyruvate kinase activity
CH55_673	COG1560	Kdo2-lipid A biosynthetic process
CH55_674	COG0739	heme binding
CH55_675	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH55_677	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH55_682	COG0494	nUDIX hydrolase
CH55_684	COG1801	Protein of unknown function DUF72
CH55_685	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH55_689	COG3102	Protein conserved in bacteria
CH55_69	COG2731	YhcH YjgK YiaL family protein
CH55_694	COG0728	peptidoglycan biosynthetic process
CH55_695	COG0673	inositol 2-dehydrogenase activity
CH55_697	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH55_70	COG3265	gluconokinase activity
CH55_700	COG3381	protein complex oligomerization
CH55_703	COG1940	carbohydrate kinase activity
CH55_704	COG0584	glycerophosphoryl diester phosphodiesterase
CH55_706	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH55_707	COG3833	ABC-type maltose transport systems, permease component
CH55_71	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_712	COG0659	secondary active sulfate transmembrane transporter activity
CH55_714	COG2912	Transglutaminase-like superfamily
CH55_715	COG3094	Invasion gene expression up-regulator, SirB
CH55_716	COG2890	protein-(glutamine-N5) methyltransferase activity
CH55_721	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH55_724	COG0012	GTP binding
CH55_73	COG1609	Transcriptional regulator
CH55_735	COG5002	protein histidine kinase activity
CH55_74	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH55_744	COG0500	methyltransferase
CH55_749	COG3328	transposase activity
CH55_750	COG3328	transposase activity
CH55_760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH55_761	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH55_762	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH55_765	COG0402	S-adenosylhomocysteine deaminase activity
CH55_77	COG0129	dihydroxy-acid dehydratase activity
CH55_775	COG0395	ABC-type sugar transport system, permease component
CH55_776	COG1175	transmembrane transport
CH55_778	COG0673	inositol 2-dehydrogenase activity
CH55_785	COG3328	transposase activity
CH55_786	COG3328	transposase activity
CH55_79	COG4575	ribosome binding
CH55_8	COG2062	phosphohistidine phosphatase, SixA
CH55_81	COG1169	isochorismate synthase
CH55_810	COG2197	response regulator
CH55_812	COG3136	membrane protein required for alginate biosynthesis
CH55_816	COG1113	amino acid transport
CH55_819	COG2837	iron assimilation
CH55_824	COG0506	proline dehydrogenase activity
CH55_824	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH55_824	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH55_830	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CH55_832	COG1191	sigma factor activity
CH55_838	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH55_840	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH55_841	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH55_844	COG1677	Flagellar hook-basal body complex protein FliE
CH55_846	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH55_848	COG1157	protein secretion by the type III secretion system
CH55_849	COG2882	bacterial-type flagellum organization
CH55_85	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH55_851	COG1580	Controls the rotational direction of flagella during chemotaxis
CH55_856	COG1987	bacterial-type flagellum assembly
CH55_860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH55_861	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_862	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_863	COG1129	ABC transporter
CH55_865	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_866	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_866	COG3347	Dehydrogenase
CH55_867	COG2390	Transcriptional regulator
CH55_869	COG1256	bacterial-type flagellum assembly
CH55_873	COG4786	Flagellar basal body rod
CH55_875	COG1749	Flagellar hook protein flgE
CH55_876	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH55_877	COG1558	bacterial-type flagellum-dependent cell motility
CH55_878	COG1815	bacterial-type flagellum-dependent cell motility
CH55_88	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH55_880	COG2747	anti-sigma28 factor FlgM
CH55_881	COG3418	PFAM FlgN family protein
CH55_883	COG1943	Transposase
CH55_886	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH55_887	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH55_892	COG2372	response to copper ion
CH55_893	COG1528	Iron-storage protein
CH55_897	COG1770	oligopeptidase
CH55_900	COG3141	response to X-ray
CH55_901	COG0513	Belongs to the DEAD box helicase family
CH55_906	COG1760	l-serine dehydratase
CH55_907	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH55_908	COG2368	4-hydroxyphenylacetate
CH55_912	COG3971	2-oxopent-4-enoate hydratase activity
CH55_914	COG3384	dioxygenase
CH55_915	COG1012	belongs to the aldehyde dehydrogenase family
CH55_918	COG1846	Transcriptional regulator
CH55_919	COG1253	flavin adenine dinucleotide binding
CH55_920	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH55_920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH55_921	COG3715	PTS system
CH55_922	COG3716	PTS system mannose fructose sorbose family IID component
CH55_927	COG5002	protein histidine kinase activity
CH55_927	COG3447	MASE1 domain protein
CH55_927	COG5001	Diguanylate cyclase
CH55_929	COG2226	methyltransferase
CH55_931	COG1278	Cold shock
CH55_934	COG1113	amino acid transport
CH55_941	COG2207	Transcriptional regulator
CH55_943	COG1132	(ABC) transporter
CH55_952	COG3328	transposase activity
CH55_953	COG2223	nitrite transmembrane transporter activity
CH55_958	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH55_96	COG1126	abc transporter atp-binding protein
CH55_963	COG3122	Protein conserved in bacteria
CH55_967	COG0534	Mate efflux family protein
CH55_97	COG0765	amino acid transport
CH55_971	COG4948	Mandelate Racemase Muconate Lactonizing
CH55_973	COG1028	Short-chain dehydrogenase reductase Sdr
CH55_974	COG3011	Protein conserved in bacteria
CH55_975	COG2271	Major facilitator Superfamily
CH55_976	COG3328	transposase activity
CH55_977	COG1470	cell adhesion involved in biofilm formation
CH55_977	COG1388	LysM domain
CH55_98	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH55_980	COG2925	Exonuclease
CH55_981	COG0531	amino acid
CH55_983	COG0371	Dehydrogenase
CH55_984	COG1129	ABC transporter
CH55_985	COG1129	ABC transporter
CH55_986	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH55_988	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH55_990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH55_992	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH55_992	COG0131	Imidazoleglycerol-phosphate dehydratase
CH55_993	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CH55_996	COG0140	phosphoribosyl-ATP diphosphatase activity
CH55_996	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH55_998	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH55_999	COG1210	Utp--glucose-1-phosphate uridylyltransferase