locus-tag	class	description
ISU63_00010	COG0592	DNA-directed DNA polymerase activity
ISU63_00025	COG0187	DNA topoisomerase II activity
ISU63_00030	COG0561	phosphatase activity
ISU63_00040	COG2423	ornithine cyclodeaminase activity
ISU63_00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISU63_00055	COG5645	(Lipo)protein
ISU63_00075	COG3977	Valine--pyruvate aminotransferase
ISU63_00085	COG0366	Alpha amylase catalytic
ISU63_00100	COG2885	chlorophyll binding
ISU63_00110	COG2818	Glycosylase
ISU63_00135	COG2213	PTS system mannitol-specific
ISU63_00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU63_00145	COG3722	fumarate hydratase activity
ISU63_00170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ISU63_00185	COG0437	4 iron, 4 sulfur cluster binding
ISU63_00190	COG2864	formate dehydrogenase
ISU63_00205	COG3276	selenocysteine insertion sequence binding
ISU63_00245	COG1349	DNA-binding transcription factor activity
ISU63_00265	COG0058	SHG alpha-glucan phosphorylase activity
ISU63_00270	COG0058	SHG alpha-glucan phosphorylase activity
ISU63_00275	COG1640	4-alpha-glucanotransferase
ISU63_00310	COG1918	ferrous iron import across plasma membrane
ISU63_00315	COG2183	response to ionizing radiation
ISU63_00320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU63_00345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ISU63_00350	COG1011	Hydrolase
ISU63_00360	COG0494	nUDIX hydrolase
ISU63_00365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ISU63_00390	COG4796	Type ii and iii secretion system protein
ISU63_00415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISU63_00420	COG0546	phosphoglycolate phosphatase activity
ISU63_00425	COG0180	Tryptophanyl-tRNA synthetase
ISU63_00445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISU63_00450	COG0402	S-adenosylhomocysteine deaminase activity
ISU63_00470	COG1486	melibiose metabolic process
ISU63_00475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU63_00480	COG0433	COG0433 Predicted ATPase
ISU63_00495	COG1289	transmembrane transporter activity
ISU63_00505	COG1765	OsmC-like protein
ISU63_00515	COG3954	Phosphoribulokinase
ISU63_00525	COG0429	hydrolase of the alpha beta-hydrolase fold
ISU63_00535	COG4521	taurine ABC transporter
ISU63_00545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU63_00550	COG2175	clavaminate synthase activity
ISU63_00560	COG1216	Glycosyl transferase, family 2
ISU63_00580	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ISU63_00585	COG1047	Peptidyl-prolyl cis-trans
ISU63_00595	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU63_00600	COG2964	Protein conserved in bacteria
ISU63_00620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ISU63_00625	COG0049	tRNA binding
ISU63_00655	COG0051	transcription antitermination factor activity, RNA binding
ISU63_00670	COG0089	rRNA binding
ISU63_00680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ISU63_00690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ISU63_00695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ISU63_00705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ISU63_00710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ISU63_00750	COG1841	ribosomal large subunit assembly
ISU63_00760	COG0201	protein transport
ISU63_00765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU63_00780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ISU63_00795	COG0789	Transcriptional regulator
ISU63_00800	COG3036	rescue of stalled ribosome
ISU63_00830	COG0758	DNA mediated transformation
ISU63_00840	COG0551	DNA topoisomerase type I activity
ISU63_00855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISU63_00870	COG0456	acetyltransferase
ISU63_00875	COG2982	Protein involved in outer membrane biogenesis
ISU63_00880	COG2233	PERMEase
ISU63_00885	COG0786	glutamate:sodium symporter activity
ISU63_00895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ISU63_00900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU63_00905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU63_00925	COG2860	membrane
ISU63_00930	COG1561	YicC-like family, N-terminal region
ISU63_00955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ISU63_00990	COG1519	Transferase
ISU63_00995	COG0859	PFAM glycosyl transferase family 9
ISU63_01000	COG0859	PFAM glycosyl transferase family 9
ISU63_01010	COG0156	8-amino-7-oxononanoate synthase activity
ISU63_01025	COG4942	peptidase
ISU63_01035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISU63_01040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU63_01055	COG1045	serine acetyltransferase
ISU63_01060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ISU63_01065	COG2169	Transcriptional regulator
ISU63_01065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU63_01070	COG2205	protein histidine kinase activity
ISU63_01075	COG0745	RESPONSE REGULATOR receiver
ISU63_01080	COG3678	ATP-independent chaperone mediated protein folding
ISU63_01105	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ISU63_01115	COG0471	metal ion transport
ISU63_01120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISU63_01125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ISU63_01130	COG0583	DNA-binding transcription factor activity
ISU63_01145	COG3152	Membrane
ISU63_01155	COG1494	fructose-1,6-bisphosphatase
ISU63_01160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU63_01165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ISU63_01205	COG1575	Belongs to the MenA family. Type 1 subfamily
ISU63_01220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU63_01225	COG1609	Transcriptional regulator
ISU63_01230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ISU63_01240	COG4682	membrane
ISU63_01255	COG0527	aspartate kinase activity
ISU63_01255	COG0460	homoserine dehydrogenase
ISU63_01280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ISU63_01295	COG1629	transport
ISU63_01320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU63_01325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU63_01325	COG0678	peroxiredoxin activity
ISU63_01395	COG1879	ABC-type sugar transport system periplasmic component
ISU63_01400	COG1129	ABC transporter
ISU63_01405	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_01410	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_01420	COG3085	chromosome segregation
ISU63_01440	COG3978	acetolactate synthase activity
ISU63_01445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU63_01485	COG0583	DNA-binding transcription factor activity
ISU63_01520	COG3121	Chaperone
ISU63_01535	COG3121	Chaperone
ISU63_01545	COG3328	transposase activity
ISU63_01555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU63_01580	COG3118	belongs to the thioredoxin family
ISU63_01585	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ISU63_01590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ISU63_01595	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU63_01600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ISU63_01605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ISU63_01610	COG1088	dTDP-glucose 4,6-dehydratase activity
ISU63_01615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ISU63_01620	COG0456	acetyltransferase
ISU63_01625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ISU63_01630	COG2244	polysaccharide biosynthetic process
ISU63_01650	COG1113	amino acid transport
ISU63_01680	COG3071	HemY protein
ISU63_01685	COG2959	enzyme of heme biosynthesis
ISU63_01690	COG1587	Uroporphyrinogen-III synthase
ISU63_01705	COG3072	Adenylate cyclase
ISU63_01725	COG3159	Protein conserved in bacteria
ISU63_01730	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ISU63_01735	COG1011	Hydrolase
ISU63_01740	COG0210	DNA helicase
ISU63_01750	COG5441	Belongs to the UPF0261 family
ISU63_01755	COG5564	TIM-barrel signal transduction protein
ISU63_01770	COG2050	protein possibly involved in aromatic compounds catabolism
ISU63_01775	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ISU63_01780	COG0514	ATP-dependent DNA helicase (RecQ)
ISU63_01785	COG1280	lysine exporter protein (LysE YggA)
ISU63_01790	COG1280	lysine exporter protein (LysE YggA)
ISU63_01795	COG2267	carboxylic ester hydrolase activity
ISU63_01800	COG0561	phosphatase activity
ISU63_01810	COG0584	glycerophosphoryl diester phosphodiesterase
ISU63_01815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU63_01825	COG0247	lactate metabolic process
ISU63_01835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ISU63_01850	COG3714	YhhN family
ISU63_01865	COG3776	membrane
ISU63_01870	COG0742	ribosomal rna small subunit methyltransferase
ISU63_01875	COG0552	protein localization to endoplasmic reticulum
ISU63_01875	COG0552	protein localization to endoplasmic reticulum
ISU63_01880	COG2884	Cell division ATP-binding protein ftsE
ISU63_01885	COG2177	Part of the ABC transporter FtsEX involved in
ISU63_01905	COG0683	leucine binding
ISU63_01915	COG4177	L-phenylalanine transmembrane transporter activity
ISU63_01925	COG0410	ABC transporter
ISU63_01985	COG0584	glycerophosphoryl diester phosphodiesterase
ISU63_01990	COG0679	Auxin Efflux Carrier
ISU63_01995	COG0697	spore germination
ISU63_02000	COG0583	DNA-binding transcription factor activity
ISU63_02010	COG0412	Dienelactone hydrolase
ISU63_02025	COG1966	Carbon starvation protein
ISU63_02030	COG0586	Pfam SNARE associated Golgi protein
ISU63_02035	COG1322	Protein conserved in bacteria
ISU63_02055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU63_02065	COG0805	protein transport
ISU63_02100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISU63_02125	COG1739	Uncharacterized protein family UPF0029
ISU63_02140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ISU63_02145	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ISU63_02175	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ISU63_02235	COG0250	Participates in transcription elongation, termination and antitermination
ISU63_02290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISU63_02325	COG1515	deoxyribonuclease V activity
ISU63_02345	COG0151	Belongs to the GarS family
ISU63_02400	COG4771	TonB-dependent receptor
ISU63_02405	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU63_02410	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ISU63_02455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU63_02465	COG5001	Diguanylate cyclase
ISU63_02495	COG0195	Participates in both transcription termination and antitermination
ISU63_02515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ISU63_02525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ISU63_02540	COG1534	Rna-binding protein
ISU63_02550	COG2027	D-alanyl-D-alanine carboxypeptidase
ISU63_02555	COG0745	RESPONSE REGULATOR receiver
ISU63_02560	COG0642	Histidine kinase
ISU63_02570	COG0697	spore germination
ISU63_02585	COG0142	geranyltranstransferase activity
ISU63_02595	COG3423	Transcriptional regulator
ISU63_02615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ISU63_02620	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ISU63_02625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ISU63_02630	COG2105	PFAM AIG2 family protein
ISU63_02635	COG2911	Protein conserved in bacteria
ISU63_02640	COG0729	surface antigen
ISU63_02650	COG1253	flavin adenine dinucleotide binding
ISU63_02660	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ISU63_02670	COG0737	Belongs to the 5'-nucleotidase family
ISU63_02680	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU63_02685	COG3061	Opacity-associated protein A
ISU63_02705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ISU63_02715	COG0360	Binds together with S18 to 16S ribosomal RNA
ISU63_02720	COG1073	alpha beta
ISU63_02740	COG3650	response to hydrogen peroxide
ISU63_02745	COG1960	acyl-CoA dehydrogenase activity
ISU63_02750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU63_02755	COG0557	exoribonuclease II activity
ISU63_02770	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ISU63_02775	COG0330	HflC and HflK could
ISU63_02780	COG0330	HflC and HflK could
ISU63_02785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ISU63_02805	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU63_02810	COG0802	atpase or kinase
ISU63_02815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ISU63_02815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ISU63_02820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ISU63_02835	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ISU63_02850	COG3264	Mechanosensitive ion channel
ISU63_02850	COG1511	domain protein
ISU63_02865	COG1053	succinate dehydrogenase
ISU63_02870	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISU63_02880	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ISU63_02925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISU63_02940	COG3383	formate dehydrogenase (NAD+) activity
ISU63_02945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU63_02950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU63_02950	COG0493	'glutamate synthase
ISU63_02955	COG1309	transcriptional regulator
ISU63_03015	COG1454	alcohol dehydrogenase
ISU63_03025	COG0629	single-stranded DNA binding
ISU63_03030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ISU63_03035	COG2315	Protein conserved in bacteria
ISU63_03040	COG1448	Aminotransferase
ISU63_03065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU63_03070	COG0735	belongs to the Fur family
ISU63_03080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ISU63_03120	COG3121	Chaperone
ISU63_03180	COG1358	cellular component organization or biogenesis
ISU63_03205	COG3721	Heme iron utilization protein
ISU63_03210	COG0702	epimerase
ISU63_03220	COG4771	TonB-dependent receptor
ISU63_03225	COG3720	iron ion transport
ISU63_03230	COG4558	Periplasmic binding protein
ISU63_03235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU63_03245	COG0626	cystathionine gamma-synthase activity
ISU63_03250	COG0814	amino acid
ISU63_03255	COG0583	DNA-binding transcription factor activity
ISU63_03260	COG0425	Belongs to the sulfur carrier protein TusA family
ISU63_03265	COG2391	methyltransferase activity
ISU63_03375	COG1301	dicarboxylic acid transport
ISU63_03385	COG3162	membrane
ISU63_03410	COG2226	methyltransferase
ISU63_03410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU63_03410	COG3433	isochorismatase activity
ISU63_03420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU63_03420	COG2226	methyltransferase
ISU63_03420	COG3433	isochorismatase activity
ISU63_03445	COG1132	(ABC) transporter
ISU63_03445	COG2375	cellular response to nickel ion
ISU63_03450	COG1132	(ABC) transporter
ISU63_03465	COG2610	gluconate transmembrane transporter activity
ISU63_03480	COG3501	Rhs element vgr protein
ISU63_03505	COG0471	metal ion transport
ISU63_03525	COG2211	Major facilitator Superfamily
ISU63_03575	COG2771	luxR family
ISU63_03580	COG3916	Acyl-homoserine-lactone synthase
ISU63_03700	COG1982	Orn Lys Arg decarboxylase major
ISU63_03705	COG1879	ABC-type sugar transport system periplasmic component
ISU63_03710	COG1129	ABC transporter
ISU63_03715	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_03720	COG4774	siderophore transport
ISU63_03740	COG1194	a g-specific adenine glycosylase
ISU63_03750	COG3171	Protein conserved in bacteria
ISU63_03775	COG3064	Membrane
ISU63_03775	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ISU63_03775	COG1073	alpha beta
ISU63_03780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU63_03785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ISU63_03795	COG0762	integral membrane protein
ISU63_03800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISU63_03805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ISU63_03810	COG2805	Type II/IV secretion system protein
ISU63_03820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU63_03835	COG0189	ligase activity
ISU63_03840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ISU63_03845	COG2356	endonuclease I
ISU63_03860	COG1166	arginine decarboxylase activity
ISU63_03875	COG0501	Belongs to the peptidase M48B family
ISU63_03880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISU63_03900	COG0191	fructose-bisphosphate aldolase activity
ISU63_03935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISU63_03945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ISU63_03965	COG0006	proline dipeptidase activity
ISU63_03970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU63_03975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU63_04020	COG1272	protein, Hemolysin III
ISU63_04045	COG0745	RESPONSE REGULATOR receiver
ISU63_04050	COG2205	protein histidine kinase activity
ISU63_04055	COG4452	Inner membrane protein CreD
ISU63_04060	COG0716	FMN binding
ISU63_04065	COG4974	Belongs to the 'phage' integrase family
ISU63_04070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU63_04075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ISU63_04095	COG0582	viral genome integration into host DNA
ISU63_04120	COG2944	sequence-specific DNA binding
ISU63_04210	COG1695	Transcriptional regulator
ISU63_04215	COG0791	NLP P60 protein
ISU63_04225	COG1879	ABC-type sugar transport system periplasmic component
ISU63_04230	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_04235	COG1129	ABC transporter
ISU63_04245	COG2182	Extracellular solute-binding protein
ISU63_04250	COG1175	transmembrane transport
ISU63_04255	COG3833	ABC-type maltose transport systems, permease component
ISU63_04260	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ISU63_04265	COG1874	Beta-galactosidase
ISU63_04270	COG1263	PTS System
ISU63_04270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU63_04290	COG2271	Major facilitator Superfamily
ISU63_04315	COG3119	arylsulfatase activity
ISU63_04320	COG0641	radical SAM
ISU63_04340	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU63_04345	COG3716	PTS system mannose fructose sorbose family IID component
ISU63_04350	COG3715	PTS system
ISU63_04355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU63_04360	COG2222	sugar isomerase
ISU63_04370	COG1349	DNA-binding transcription factor activity
ISU63_04375	COG3119	arylsulfatase activity
ISU63_04415	COG0288	reversible hydration of carbon dioxide
ISU63_04435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU63_04455	COG2165	general secretion pathway protein
ISU63_04500	COG0840	transmembrane signaling receptor activity
ISU63_04515	COG0583	DNA-binding transcription factor activity
ISU63_04520	COG2814	Major facilitator Superfamily
ISU63_04525	COG0583	DNA-binding transcription factor activity
ISU63_04535	COG1609	Transcriptional regulator
ISU63_04565	COG0667	Aldo Keto reductase
ISU63_04615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ISU63_04625	COG1074	ATP-dependent DNA helicase activity
ISU63_04630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ISU63_04640	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU63_04655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ISU63_04660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ISU63_04665	COG2166	iron-sulfur cluster assembly
ISU63_04670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISU63_04680	COG0583	DNA-binding transcription factor activity
ISU63_04685	COG2363	Small membrane protein
ISU63_04700	COG1611	Belongs to the LOG family
ISU63_04720	COG3098	single-species biofilm formation
ISU63_04725	COG0564	pseudouridine synthase activity
ISU63_04790	COG0575	Belongs to the CDS family
ISU63_04795	COG0750	zinc metalloprotease
ISU63_04810	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ISU63_04835	COG0587	DNA-directed DNA polymerase activity
ISU63_04845	COG0346	lactoylglutathione lyase activity
ISU63_04850	COG0037	tRNA processing
ISU63_04860	COG4568	rho-dependent transcription termination
ISU63_04870	COG4681	YaeQ
ISU63_04880	COG3015	lipoprotein NlpE involved in copper resistance
ISU63_04890	COG1720	tRNA m6t6A37 methyltransferase activity
ISU63_04900	COG1464	Belongs to the NlpA lipoprotein family
ISU63_04905	COG2011	ABC-type metal ion transport system permease component
ISU63_04915	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU63_04945	COG0656	L-ascorbic acid biosynthetic process
ISU63_04960	COG0741	lytic transglycosylase activity
ISU63_04960	COG1388	LysM domain
ISU63_04965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU63_04970	COG2226	methyltransferase
ISU63_04990	COG1953	Uracil, thiamine, allantoin
ISU63_05015	COG3657	addiction module killer protein
ISU63_05065	COG0582	viral genome integration into host DNA
ISU63_05085	COG2867	negative regulation of translational initiation
ISU63_05095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU63_05100	COG0497	DNA recombination
ISU63_05105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ISU63_05120	COG2009	succinate dehydrogenase
ISU63_05125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ISU63_05130	COG1053	succinate dehydrogenase
ISU63_05140	COG0567	Dehydrogenase, E1 component
ISU63_05145	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU63_05155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ISU63_05160	COG1271	oxidase subunit
ISU63_05165	COG1294	oxidase, subunit
ISU63_05170	COG4890	Cyd operon protein YbgT
ISU63_05175	COG3790	cyd operon protein YbgE
ISU63_05180	COG0824	Thioesterase
ISU63_05185	COG0811	peptide transport
ISU63_05190	COG0848	biopolymer transport protein
ISU63_05195	COG3064	Membrane
ISU63_05195	COG3064	Membrane
ISU63_05205	COG2885	chlorophyll binding
ISU63_05210	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ISU63_05240	COG1230	cation diffusion facilitator family transporter
ISU63_05245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU63_05260	COG2017	converts alpha-aldose to the beta-anomer
ISU63_05275	COG1085	galactose-1-phosphate uridylyltransferase
ISU63_05280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ISU63_05290	COG1119	ATPase activity
ISU63_05295	COG3585	molybdate ion transport
ISU63_05295	COG2005	Transcriptional regulator
ISU63_05305	COG0725	ABC transporter, periplasmic molybdate-binding protein
ISU63_05310	COG4149	molybdate abc transporter
ISU63_05320	COG0561	phosphatase activity
ISU63_05345	COG2226	methyltransferase
ISU63_05355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ISU63_05365	COG4628	conserved protein (DUF2132)
ISU63_05370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ISU63_05375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ISU63_05385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ISU63_05390	COG0314	molybdopterin synthase activity
ISU63_05395	COG0670	Belongs to the BI1 family
ISU63_05420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU63_05425	COG0583	DNA-binding transcription factor activity
ISU63_05435	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ISU63_05470	COG1902	pentaerythritol trinitrate reductase activity
ISU63_05490	COG0842	Transport permease protein
ISU63_05495	COG0842	Transport permease protein
ISU63_05500	COG1131	(ABC) transporter
ISU63_05510	COG1309	transcriptional regulator
ISU63_05515	COG0513	Belongs to the DEAD box helicase family
ISU63_05550	COG3328	transposase activity
ISU63_05565	COG0351	phosphomethylpyrimidine kinase
ISU63_05590	COG0826	peptidase U32
ISU63_05595	COG3422	double-strand break repair
ISU63_05600	COG0745	RESPONSE REGULATOR receiver
ISU63_05630	COG3842	ATPase activity
ISU63_05640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISU63_05650	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU63_05655	COG1177	transmembrane transport
ISU63_05660	COG0443	Heat shock 70 kDa protein
ISU63_05665	COG2239	Acts as a magnesium transporter
ISU63_05680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ISU63_05690	COG0581	inorganic phosphate transmembrane transporter activity
ISU63_05705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU63_05710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ISU63_05735	COG1393	Belongs to the ArsC family
ISU63_05740	COG4783	chaperone-mediated protein folding
ISU63_05745	COG0628	permease
ISU63_05755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ISU63_05760	COG2716	regulation of RNA biosynthetic process
ISU63_05770	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ISU63_05785	COG2321	neutral zinc metallopeptidase
ISU63_05805	COG1876	peptidase activity
ISU63_05815	COG1393	Belongs to the ArsC family
ISU63_05830	COG1175	transmembrane transport
ISU63_05835	COG3842	ATPase activity
ISU63_05845	COG3119	arylsulfatase activity
ISU63_05850	COG0641	radical SAM
ISU63_05855	COG1988	membrane-bound metal-dependent
ISU63_05865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU63_05875	COG2197	response regulator
ISU63_05880	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU63_05880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU63_05885	COG3062	negative regulation of establishment of protein localization
ISU63_05895	COG3043	anaerobic respiration
ISU63_05900	COG3005	denitrification pathway
ISU63_05940	COG3111	PFAM Bacterial OB fold (BOF) protein
ISU63_05950	COG2837	iron assimilation
ISU63_05955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISU63_05965	COG4886	Leucine-rich repeat (LRR) protein
ISU63_05975	COG2731	YhcH YjgK YiaL family protein
ISU63_05980	COG1737	Transcriptional regulator
ISU63_05990	COG4150	thiosulfate binding
ISU63_05995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ISU63_06000	COG4208	sulfate ABC transporter
ISU63_06005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ISU63_06020	COG0745	RESPONSE REGULATOR receiver
ISU63_06025	COG3850	Histidine kinase
ISU63_06025	COG5002	protein histidine kinase activity
ISU63_06035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISU63_06055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ISU63_06070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU63_06075	COG0745	RESPONSE REGULATOR receiver
ISU63_06080	COG2205	protein histidine kinase activity
ISU63_06110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU63_06120	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ISU63_06135	COG3530	Putative quorum-sensing-regulated virulence factor
ISU63_06200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU63_06215	COG0667	Aldo Keto reductase
ISU63_06240	COG0436	Aminotransferase
ISU63_06245	COG3038	cytochrome b561
ISU63_06275	COG3381	protein complex oligomerization
ISU63_06280	COG3302	dmso reductase anchor subunit
ISU63_06285	COG0437	4 iron, 4 sulfur cluster binding
ISU63_06290	COG0243	molybdopterin cofactor binding
ISU63_06325	COG2951	lytic endotransglycosylase activity
ISU63_06385	COG3121	Chaperone
ISU63_06390	COG3188	usher protein
ISU63_06395	COG3328	transposase activity
ISU63_06405	COG2824	Alkylphosphonate utilization operon protein PhnA
ISU63_06415	COG1704	LemA family
ISU63_06435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU63_06440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU63_06445	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU63_06455	COG1138	Cytochrome C-type biogenesis protein
ISU63_06460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISU63_06465	COG3088	subunit of a heme lyase
ISU63_06465	COG4235	cytochrome complex assembly
ISU63_06470	COG4235	cytochrome complex assembly
ISU63_06470	COG3088	subunit of a heme lyase
ISU63_06485	COG3691	Protein conserved in bacteria
ISU63_06500	COG2062	phosphohistidine phosphatase, SixA
ISU63_06510	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU63_06525	COG0730	response to heat
ISU63_06530	COG3101	peptidyl-lysine hydroxylation
ISU63_06545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU63_06550	COG1794	racemase activity, acting on amino acids and derivatives
ISU63_06565	COG0697	spore germination
ISU63_06580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU63_06590	COG0586	Pfam SNARE associated Golgi protein
ISU63_06600	COG0285	dihydrofolate synthase activity
ISU63_06605	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ISU63_06610	COG1286	toxin biosynthetic process
ISU63_06615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ISU63_06625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_06630	COG4215	(ABC) transporter
ISU63_06635	COG4160	amino acid transport
ISU63_06640	COG4598	ABC transporter
ISU63_06645	COG1090	epimerase
ISU63_06655	COG0622	Phosphoesterase
ISU63_06660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ISU63_06665	COG3037	sugar-specific permease SgaT UlaA
ISU63_06670	COG3328	transposase activity
ISU63_06685	COG1609	Transcriptional regulator
ISU63_06690	COG0280	phosphate acetyltransferase
ISU63_06690	COG0857	belongs to the CobB CobQ family
ISU63_06710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU63_06715	COG0490	domain, Protein
ISU63_06715	COG0471	metal ion transport
ISU63_06730	COG0436	Aminotransferase
ISU63_06735	COG0583	DNA-binding transcription factor activity
ISU63_06745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU63_06765	COG1034	ATP synthesis coupled electron transport
ISU63_06780	COG0839	Belongs to the complex I subunit 6 family
ISU63_06790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ISU63_06795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU63_06810	COG2731	YhcH YjgK YiaL family protein
ISU63_06815	COG3265	gluconokinase activity
ISU63_06820	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_06825	COG1649	PFAM Uncharacterised BCR, COG1649
ISU63_06830	COG1609	Transcriptional regulator
ISU63_06835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU63_06850	COG0129	dihydroxy-acid dehydratase activity
ISU63_06855	COG4575	ribosome binding
ISU63_06865	COG1169	isochorismate synthase
ISU63_06880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ISU63_06895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISU63_06930	COG1126	abc transporter atp-binding protein
ISU63_06935	COG0765	amino acid transport
ISU63_06940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_06970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ISU63_06990	COG1063	alcohol dehydrogenase
ISU63_06995	COG1879	ABC-type sugar transport system periplasmic component
ISU63_07000	COG1129	ABC transporter
ISU63_07005	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_07010	COG1609	Transcriptional regulator
ISU63_07015	COG0583	DNA-binding transcription factor activity
ISU63_07020	COG0473	3-isopropylmalate dehydrogenase activity
ISU63_07030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU63_07040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU63_07045	COG2831	hemolysin activation secretion protein
ISU63_07050	COG3210	domain, Protein
ISU63_07090	COG3210	domain, Protein
ISU63_07100	COG3842	ATPase activity
ISU63_07110	COG1609	Transcriptional regulator
ISU63_07125	COG0395	ABC-type sugar transport system, permease component
ISU63_07130	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ISU63_07150	COG0668	transmembrane transport
ISU63_07155	COG1518	maintenance of DNA repeat elements
ISU63_07160	COG1203	CRISPR-associated helicase, Cas3
ISU63_07185	COG0667	Aldo Keto reductase
ISU63_07195	COG0477	Major facilitator Superfamily
ISU63_07205	COG0583	DNA-binding transcription factor activity
ISU63_07210	COG2771	luxR family
ISU63_07215	COG3916	Acyl-homoserine-lactone synthase
ISU63_07235	COG0628	permease
ISU63_07255	COG3328	transposase activity
ISU63_07275	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ISU63_07285	COG3328	transposase activity
ISU63_07290	COG1530	ribonuclease E activity
ISU63_07295	COG0564	pseudouridine synthase activity
ISU63_07300	COG0424	maF-like protein
ISU63_07305	COG1399	metal-binding, possibly nucleic acid-binding protein
ISU63_07310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ISU63_07340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU63_07350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU63_07355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ISU63_07365	COG0470	DNA polymerase III
ISU63_07370	COG0084	hydrolase, TatD family'
ISU63_07375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU63_07375	COG1263	PTS System
ISU63_07385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISU63_07390	COG0537	adenosine 5'-monophosphoramidase activity
ISU63_07395	COG5633	Lipoprotein
ISU63_07410	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU63_07420	COG1252	NADH dehydrogenase
ISU63_07435	COG3328	transposase activity
ISU63_07440	COG3134	Outer membrane lipoprotein
ISU63_07445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ISU63_07450	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU63_07460	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU63_07465	COG1940	carbohydrate kinase activity
ISU63_07485	COG2850	peptidyl-arginine hydroxylation
ISU63_07495	COG0745	RESPONSE REGULATOR receiver
ISU63_07505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISU63_07525	COG1187	pseudouridine synthase activity
ISU63_07530	COG0538	isocitrate dehydrogenase activity
ISU63_07545	COG0840	transmembrane signaling receptor activity
ISU63_07550	COG0702	epimerase
ISU63_07555	COG1733	regulation of RNA biosynthetic process
ISU63_07580	COG1522	sequence-specific DNA binding
ISU63_07595	COG0604	alcohol dehydrogenase
ISU63_07595	COG3321	synthase
ISU63_07595	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_07620	COG1285	pathogenesis
ISU63_07645	COG1360	Flagellar Motor Protein
ISU63_07650	COG0643	Histidine kinase
ISU63_07650	COG2198	Histidine kinase
ISU63_07655	COG0835	chemotaxis
ISU63_07660	COG2271	Major facilitator Superfamily
ISU63_07665	COG0251	oxidation-reduction process
ISU63_07675	COG2964	Protein conserved in bacteria
ISU63_07695	COG0840	transmembrane signaling receptor activity
ISU63_07700	COG0840	transmembrane signaling receptor activity
ISU63_07705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ISU63_07715	COG0745	RESPONSE REGULATOR receiver
ISU63_07720	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ISU63_07725	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU63_07735	COG5295	Hep Hag repeat protein
ISU63_07745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ISU63_07800	COG3121	Chaperone
ISU63_07820	COG3008	intermembrane lipid transfer
ISU63_07825	COG2995	paraquat-inducible protein a
ISU63_07830	COG1956	GAF domain-containing protein
ISU63_07840	COG0793	Belongs to the peptidase S41A family
ISU63_07850	COG3539	Fimbrial protein
ISU63_07855	COG3121	Chaperone
ISU63_07870	COG3121	Chaperone
ISU63_07875	COG2814	Major facilitator Superfamily
ISU63_07880	COG0823	Involved in the tonB-independent uptake of proteins
ISU63_07890	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU63_07895	COG1823	symporter activity
ISU63_07900	COG1988	membrane-bound metal-dependent
ISU63_07905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU63_07910	COG1653	transport
ISU63_07915	COG3842	ATPase activity
ISU63_07920	COG0395	ABC-type sugar transport system, permease component
ISU63_07925	COG1175	transmembrane transport
ISU63_07935	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_07945	COG1917	Cupin 2, conserved barrel domain protein
ISU63_07950	COG3328	transposase activity
ISU63_07955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU63_07965	COG3001	Fructosamine kinase
ISU63_07975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU63_07980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU63_07985	COG1121	(ABC) transporter
ISU63_07990	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISU63_08010	COG4249	Peptidase C14 caspase catalytic subunit p20
ISU63_08045	COG0072	phenylalanine-tRNA ligase activity
ISU63_08045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ISU63_08050	COG0776	regulation of translation
ISU63_08065	COG0386	Belongs to the glutathione peroxidase family
ISU63_08115	COG0791	NLP P60 protein
ISU63_08140	COG0574	Belongs to the PEP-utilizing enzyme family
ISU63_08140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU63_08150	COG0628	permease
ISU63_08155	COG0277	FAD linked oxidase domain protein
ISU63_08155	COG0247	lactate metabolic process
ISU63_08160	COG2050	protein possibly involved in aromatic compounds catabolism
ISU63_08165	COG0316	Belongs to the HesB IscA family
ISU63_08170	COG0719	Fe-S assembly protein
ISU63_08175	COG0396	ATPase activity
ISU63_08180	COG0719	Fe-S assembly protein
ISU63_08195	COG1388	LysM domain
ISU63_08195	COG1376	ErfK ybiS ycfS ynhG family protein
ISU63_08250	COG0307	riboflavin synthase, alpha
ISU63_08255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ISU63_08260	COG2814	Major facilitator Superfamily
ISU63_08265	COG0583	DNA-binding transcription factor activity
ISU63_08285	COG0791	NLP P60 protein
ISU63_08290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ISU63_08300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISU63_08305	COG0346	lactoylglutathione lyase activity
ISU63_08315	COG1902	pentaerythritol trinitrate reductase activity
ISU63_08320	COG1309	transcriptional regulator
ISU63_08325	COG2194	sulfuric ester hydrolase activity
ISU63_08335	COG3133	Outer membrane lipoprotein
ISU63_08345	COG3895	Periplasmic Protein
ISU63_08365	COG0625	glutathione transferase activity
ISU63_08380	COG3104	oligopeptide transport
ISU63_08385	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU63_08385	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU63_08390	COG4172	Belongs to the ABC transporter superfamily
ISU63_08400	COG4171	peptide transport system, permease
ISU63_08405	COG4168	peptide transport system, permease
ISU63_08410	COG4166	transmembrane transport
ISU63_08420	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISU63_08425	COG1842	Phage shock protein A
ISU63_08435	COG1983	PspC domain protein
ISU63_08445	COG3106	COG3106 Predicted ATPase
ISU63_08455	COG5654	RES domain protein
ISU63_08460	COG5642	Protein of unknown function (DUF2384)
ISU63_08475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ISU63_08480	COG4948	Mandelate Racemase Muconate Lactonizing
ISU63_08485	COG2866	Carboxypeptidase
ISU63_08490	COG4166	transmembrane transport
ISU63_08505	COG0657	acetylesterase activity
ISU63_08515	COG0674	pyruvate-flavodoxin oxidoreductase activity
ISU63_08515	COG1013	pyruvate-flavodoxin oxidoreductase activity
ISU63_08515	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ISU63_08515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU63_08525	COG1285	pathogenesis
ISU63_08530	COG3042	response to heat
ISU63_08535	COG3187	Heat shock protein
ISU63_08540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU63_08545	COG2911	Protein conserved in bacteria
ISU63_08555	COG3784	Protein of unknown function (DUF1318)
ISU63_08560	COG0246	Mannitol dehydrogenase
ISU63_08565	COG2390	Transcriptional regulator
ISU63_08575	COG1643	Atp-dependent helicase
ISU63_08590	COG3591	Belongs to the peptidase S1B family
ISU63_08620	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ISU63_08625	COG2205	protein histidine kinase activity
ISU63_08630	COG0745	RESPONSE REGULATOR receiver
ISU63_08640	COG0531	amino acid
ISU63_08650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ISU63_08655	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ISU63_08660	COG0589	response to stress
ISU63_08665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISU63_08670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU63_08685	COG1011	Hydrolase
ISU63_08690	COG0440	acetolactate synthase activity
ISU63_08695	COG0028	Belongs to the TPP enzyme family
ISU63_08725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ISU63_08735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU63_08755	COG1609	Transcriptional regulator
ISU63_08760	COG0038	chloride channel
ISU63_08765	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ISU63_08770	COG1940	carbohydrate kinase activity
ISU63_08775	COG0583	DNA-binding transcription factor activity
ISU63_08780	COG2814	Major facilitator Superfamily
ISU63_08790	COG0114	fumarate hydratase activity
ISU63_08800	COG5339	Protein conserved in bacteria
ISU63_08810	COG0385	Bile acid
ISU63_08815	COG0673	inositol 2-dehydrogenase activity
ISU63_08825	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_08830	COG1129	ABC transporter
ISU63_08835	COG1879	ABC-type sugar transport system periplasmic component
ISU63_08850	COG2274	protein secretion by the type I secretion system
ISU63_08855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU63_08865	COG2274	protein secretion by the type I secretion system
ISU63_08895	COG2207	Transcriptional regulator
ISU63_08895	COG3708	Transcriptional regulator
ISU63_08900	COG4658	electron transport chain
ISU63_08905	COG4659	FMN binding
ISU63_08915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ISU63_08920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU63_08925	COG2271	Major facilitator Superfamily
ISU63_08935	COG1966	Carbon starvation protein
ISU63_08940	COG2879	small protein
ISU63_08945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISU63_08965	COG0023	Translation Initiation Factor
ISU63_08980	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ISU63_08985	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ISU63_08990	COG0671	phosphoesterase, PA-phosphatase related
ISU63_09000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISU63_09010	COG0583	DNA-binding transcription factor activity
ISU63_09030	COG0616	signal peptide processing
ISU63_09035	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_09045	COG1187	pseudouridine synthase activity
ISU63_09050	COG0009	L-threonylcarbamoyladenylate synthase
ISU63_09070	COG0512	Glutamine amidotransferase of anthranilate synthase
ISU63_09080	COG0134	indole-3-glycerol-phosphate synthase activity
ISU63_09080	COG0135	phosphoribosylanthranilate isomerase activity
ISU63_09100	COG3047	cAMP biosynthetic process
ISU63_09135	COG3328	transposase activity
ISU63_09140	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ISU63_09145	COG2350	Protein conserved in bacteria
ISU63_09190	COG4608	Belongs to the ABC transporter superfamily
ISU63_09195	COG0444	Belongs to the ABC transporter superfamily
ISU63_09200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU63_09205	COG0601	transmembrane transport
ISU63_09215	COG2095	MarC family integral membrane protein
ISU63_09220	COG1454	alcohol dehydrogenase
ISU63_09220	COG1012	belongs to the aldehyde dehydrogenase family
ISU63_09250	COG0745	RESPONSE REGULATOR receiver
ISU63_09260	COG0788	formyltetrahydrofolate deformylase activity
ISU63_09265	COG3328	transposase activity
ISU63_09285	COG0583	DNA-binding transcription factor activity
ISU63_09290	COG0708	Exodeoxyribonuclease III
ISU63_09295	COG0494	nUDIX hydrolase
ISU63_09305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ISU63_09310	COG0709	Synthesizes selenophosphate from selenide and ATP
ISU63_09315	COG0778	Nitroreductase
ISU63_09320	COG0616	signal peptide processing
ISU63_09325	COG0252	asparaginase activity
ISU63_09330	COG1335	isochorismatase
ISU63_09335	COG3139	Protein of unknown function (DUF1315)
ISU63_09355	COG3713	MltA-interacting MipA family protein
ISU63_09360	COG2766	serine protein kinase
ISU63_09375	COG0583	DNA-binding transcription factor activity
ISU63_09385	COG2814	Major facilitator Superfamily
ISU63_09395	COG2719	SpoVR family
ISU63_09425	COG1104	cysteine desulfurase activity
ISU63_09435	COG3328	transposase activity
ISU63_09595	COG3328	transposase activity
ISU63_09695	COG0582	viral genome integration into host DNA
ISU63_09705	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISU63_09710	COG2951	lytic endotransglycosylase activity
ISU63_09725	COG2894	cell division
ISU63_09730	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ISU63_09735	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ISU63_09740	COG0318	PFAM AMP-dependent synthetase and ligase
ISU63_09750	COG3065	identical protein binding
ISU63_09760	COG1199	ATP-dependent helicase activity
ISU63_09765	COG0251	oxidation-reduction process
ISU63_09780	COG0800	Aldolase
ISU63_09785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ISU63_09790	COG1737	Transcriptional regulator
ISU63_09795	COG0469	pyruvate kinase activity
ISU63_09805	COG1560	Kdo2-lipid A biosynthetic process
ISU63_09810	COG0739	heme binding
ISU63_09815	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ISU63_09825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU63_09850	COG0494	nUDIX hydrolase
ISU63_09860	COG1801	Protein of unknown function DUF72
ISU63_09865	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ISU63_09885	COG3102	Protein conserved in bacteria
ISU63_09905	COG0728	peptidoglycan biosynthetic process
ISU63_09915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU63_09930	COG3381	protein complex oligomerization
ISU63_09945	COG1940	carbohydrate kinase activity
ISU63_09950	COG0584	glycerophosphoryl diester phosphodiesterase
ISU63_09970	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU63_09975	COG3833	ABC-type maltose transport systems, permease component
ISU63_09995	COG0659	secondary active sulfate transmembrane transporter activity
ISU63_10015	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU63_10040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ISU63_10055	COG0012	GTP binding
ISU63_10105	COG5002	protein histidine kinase activity
ISU63_10150	COG0500	methyltransferase
ISU63_10170	COG3328	transposase activity
ISU63_10215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU63_10220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU63_10225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU63_10240	COG0402	S-adenosylhomocysteine deaminase activity
ISU63_10305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU63_10315	COG3850	Histidine kinase
ISU63_10320	COG0387	Pfam Sodium calcium exchanger
ISU63_10325	COG1702	phosphate starvation-inducible protein PhoH
ISU63_10340	COG3658	cytochrome
ISU63_10345	COG1215	transferase activity, transferring glycosyl groups
ISU63_10350	COG1649	PFAM Uncharacterised BCR, COG1649
ISU63_10350	COG0726	polysaccharide deacetylase
ISU63_10355	COG0457	Tetratricopeptide repeat
ISU63_10360	COG0006	proline dipeptidase activity
ISU63_10380	COG0577	efflux transmembrane transporter activity
ISU63_10380	COG1136	(ABC) transporter
ISU63_10405	COG0672	)-iron permease
ISU63_10420	COG2066	Belongs to the glutaminase family
ISU63_10430	COG1349	DNA-binding transcription factor activity
ISU63_10440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU63_10445	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU63_10460	COG2814	Major facilitator Superfamily
ISU63_10485	COG2030	dehydratase
ISU63_10490	COG0427	acetyl-CoA hydrolase
ISU63_10500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_10500	COG2205	protein histidine kinase activity
ISU63_10515	COG3188	usher protein
ISU63_10525	COG3121	Chaperone
ISU63_10535	COG0582	viral genome integration into host DNA
ISU63_10540	COG1169	isochorismate synthase
ISU63_10545	COG2814	Major facilitator Superfamily
ISU63_10550	COG1132	(ABC) transporter
ISU63_10565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU63_10565	COG2226	methyltransferase
ISU63_10565	COG3433	isochorismatase activity
ISU63_10585	COG1021	2,3-dihydroxybenzoate-AMP ligase
ISU63_10590	COG4771	TonB-dependent receptor
ISU63_10650	COG3842	ATPase activity
ISU63_10655	COG0395	ABC-type sugar transport system, permease component
ISU63_10660	COG1175	transmembrane transport
ISU63_10670	COG0673	inositol 2-dehydrogenase activity
ISU63_10675	COG2188	Transcriptional regulator
ISU63_10800	COG2197	response regulator
ISU63_10810	COG3136	membrane protein required for alginate biosynthesis
ISU63_10830	COG1113	amino acid transport
ISU63_10850	COG2822	iron ion transport
ISU63_10855	COG0672	)-iron permease
ISU63_10870	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU63_10870	COG0506	proline dehydrogenase activity
ISU63_10870	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU63_10885	COG1126	abc transporter atp-binding protein
ISU63_10890	COG0765	amino acid transport
ISU63_10895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_10910	COG1191	sigma factor activity
ISU63_10940	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ISU63_10945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ISU63_10950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ISU63_10970	COG1677	Flagellar hook-basal body complex protein FliE
ISU63_10990	COG1157	protein secretion by the type III secretion system
ISU63_11005	COG1580	Controls the rotational direction of flagella during chemotaxis
ISU63_11030	COG1987	bacterial-type flagellum assembly
ISU63_11050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU63_11055	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_11060	COG1129	ABC transporter
ISU63_11070	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_11075	COG3347	Dehydrogenase
ISU63_11075	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_11080	COG2390	Transcriptional regulator
ISU63_11090	COG1256	bacterial-type flagellum assembly
ISU63_11130	COG1558	bacterial-type flagellum-dependent cell motility
ISU63_11135	COG1815	bacterial-type flagellum-dependent cell motility
ISU63_11145	COG2747	anti-sigma28 factor FlgM
ISU63_11150	COG3418	PFAM FlgN family protein
ISU63_11175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU63_11180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU63_11205	COG2372	response to copper ion
ISU63_11210	COG1528	Iron-storage protein
ISU63_11225	COG1770	oligopeptidase
ISU63_11240	COG3141	response to X-ray
ISU63_11245	COG0513	Belongs to the DEAD box helicase family
ISU63_11270	COG1760	l-serine dehydratase
ISU63_11275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISU63_11280	COG2368	4-hydroxyphenylacetate
ISU63_11295	COG3971	2-oxopent-4-enoate hydratase activity
ISU63_11305	COG3384	dioxygenase
ISU63_11310	COG1012	belongs to the aldehyde dehydrogenase family
ISU63_11325	COG1846	Transcriptional regulator
ISU63_11330	COG1253	flavin adenine dinucleotide binding
ISU63_11335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU63_11335	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU63_11340	COG3715	PTS system
ISU63_11345	COG3716	PTS system mannose fructose sorbose family IID component
ISU63_11375	COG2226	methyltransferase
ISU63_11380	COG1496	oxidoreductase activity
ISU63_11400	COG1113	amino acid transport
ISU63_11435	COG2207	Transcriptional regulator
ISU63_11445	COG1132	(ABC) transporter
ISU63_11490	COG3328	transposase activity
ISU63_11495	COG2223	nitrite transmembrane transporter activity
ISU63_11515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ISU63_11540	COG3122	Protein conserved in bacteria
ISU63_11560	COG0534	Mate efflux family protein
ISU63_11575	COG4948	Mandelate Racemase Muconate Lactonizing
ISU63_11585	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_11590	COG3011	Protein conserved in bacteria
ISU63_11595	COG2271	Major facilitator Superfamily
ISU63_11600	COG1470	cell adhesion involved in biofilm formation
ISU63_11600	COG1388	LysM domain
ISU63_11605	COG3328	transposase activity
ISU63_11620	COG2925	Exonuclease
ISU63_11630	COG0531	amino acid
ISU63_11640	COG0371	Dehydrogenase
ISU63_11645	COG1129	ABC transporter
ISU63_11650	COG1129	ABC transporter
ISU63_11655	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_11670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU63_11685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ISU63_11695	COG0131	Imidazoleglycerol-phosphate dehydratase
ISU63_11695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU63_11715	COG0140	phosphoribosyl-ATP diphosphatase activity
ISU63_11715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ISU63_11725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU63_11730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU63_11745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU63_11750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU63_11755	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU63_11760	COG1120	ATPase activity
ISU63_11775	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ISU63_11780	COG0076	glutamate decarboxylase activity
ISU63_11785	COG4114	ferric iron reductase
ISU63_11790	COG1253	flavin adenine dinucleotide binding
ISU63_11795	COG2982	Protein involved in outer membrane biogenesis
ISU63_11810	COG0489	protein tyrosine kinase activity
ISU63_11840	COG2814	Major facilitator Superfamily
ISU63_11850	COG1346	cytolysis
ISU63_11865	COG2949	membrane
ISU63_11870	COG4211	Belongs to the binding-protein-dependent transport system permease family
ISU63_11885	COG2311	Membrane
ISU63_11895	COG0477	Major facilitator Superfamily
ISU63_11900	COG0583	DNA-binding transcription factor activity
ISU63_11930	COG1136	(ABC) transporter
ISU63_11940	COG0303	'Molybdopterin
ISU63_11950	COG3328	transposase activity
ISU63_11960	COG0488	(ABC) transporter
ISU63_12090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISU63_12095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ISU63_12105	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_12110	COG1024	Enoyl-CoA hydratase
ISU63_12120	COG3425	synthase
ISU63_12125	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_12130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU63_12135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ISU63_12145	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_12170	COG2920	part of a sulfur-relay system
ISU63_12190	COG1832	CoA-binding protein
ISU63_12205	COG0210	DNA helicase
ISU63_12210	COG3304	Inner membrane component domain
ISU63_12215	COG1289	transmembrane transporter activity
ISU63_12220	COG3070	regulator of competence-specific genes
ISU63_12245	COG1067	ATP-dependent peptidase activity
ISU63_12280	COG3130	regulation of translation
ISU63_12285	COG3009	Protein conserved in bacteria
ISU63_12290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU63_12290	COG3008	intermembrane lipid transfer
ISU63_12295	COG2995	paraquat-inducible protein a
ISU63_12300	COG0488	(ABC) transporter
ISU63_12310	COG3217	Mosc domain protein beta barrel domain protein
ISU63_12310	COG0633	Ferredoxin
ISU63_12325	COG0308	aminopeptidase N
ISU63_12345	COG1448	Aminotransferase
ISU63_12355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU63_12360	COG3108	Peptidase M15
ISU63_12365	COG2989	Protein conserved in bacteria
ISU63_12390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISU63_12395	COG3173	Aminoglycoside phosphotransferase
ISU63_12410	COG1278	Cold shock
ISU63_12415	COG5383	Protein conserved in bacteria
ISU63_12430	COG0658	competence protein
ISU63_12430	COG2333	competence protein COMEC
ISU63_12440	COG0539	negative regulation of cytoplasmic translation
ISU63_12465	COG5295	Hep Hag repeat protein
ISU63_12465	COG5295	Hep Hag repeat protein
ISU63_12470	COG0252	asparaginase activity
ISU63_12475	COG1944	ATP diphosphatase activity
ISU63_12480	COG2116	formate transmembrane transporter activity
ISU63_12485	COG1882	Formate acetyltransferase
ISU63_12495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISU63_12525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ISU63_12535	COG1674	ftsk spoiiie
ISU63_12535	COG3107	peptidoglycan biosynthetic process
ISU63_12545	COG0492	ferredoxin-NADP+ reductase activity
ISU63_12555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ISU63_12565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ISU63_12585	COG1278	Cold shock
ISU63_12595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU63_12600	COG2990	Protein conserved in bacteria
ISU63_12605	COG3593	DNA synthesis involved in DNA repair
ISU63_12610	COG2431	L-lysine efflux transmembrane transporter activity
ISU63_12620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU63_12625	COG0028	Belongs to the TPP enzyme family
ISU63_12635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ISU63_12640	COG0702	epimerase
ISU63_12645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU63_12655	COG1605	Chorismate mutase
ISU63_12660	COG1126	abc transporter atp-binding protein
ISU63_12665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_12670	COG4215	(ABC) transporter
ISU63_12675	COG4160	amino acid transport
ISU63_12700	COG1120	ATPase activity
ISU63_12705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU63_12710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU63_12735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_12750	COG1177	transmembrane transport
ISU63_12755	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU63_12760	COG3842	ATPase activity
ISU63_12765	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISU63_12795	COG0671	phosphoesterase, PA-phosphatase related
ISU63_12805	COG1349	DNA-binding transcription factor activity
ISU63_12810	COG0814	amino acid
ISU63_12815	COG1686	Belongs to the peptidase S11 family
ISU63_12820	COG2011	ABC-type metal ion transport system permease component
ISU63_12845	COG0625	glutathione transferase activity
ISU63_12850	COG4771	TonB-dependent receptor
ISU63_12860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU63_12870	COG0833	amino acid
ISU63_12875	COG0583	DNA-binding transcription factor activity
ISU63_12880	COG2855	membrane
ISU63_12890	COG3188	usher protein
ISU63_12895	COG3121	Chaperone
ISU63_12910	COG3710	Transcriptional regulator
ISU63_12915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU63_12915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU63_12915	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ISU63_12920	COG1105	Belongs to the carbohydrate kinase PfkB family
ISU63_12930	COG0494	nUDIX hydrolase
ISU63_12940	COG1129	ABC transporter
ISU63_12975	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_13000	COG0246	Mannitol dehydrogenase
ISU63_13005	COG2186	Transcriptional regulator
ISU63_13010	COG0523	cobalamin synthesis protein
ISU63_13015	COG0671	phosphoesterase, PA-phosphatase related
ISU63_13020	COG0791	NLP P60 protein
ISU63_13025	COG2200	EAL domain
ISU63_13030	COG4166	transmembrane transport
ISU63_13035	COG4174	ABC transporter (Permease)
ISU63_13040	COG4239	(ABC) transporter, permease
ISU63_13045	COG4172	Belongs to the ABC transporter superfamily
ISU63_13055	COG2814	Major facilitator Superfamily
ISU63_13060	COG1187	pseudouridine synthase activity
ISU63_13065	COG1061	Type III restriction enzyme res subunit
ISU63_13085	COG3082	Protein of unknown function (DUF1414)
ISU63_13090	COG3083	sulfuric ester hydrolase activity
ISU63_13105	COG3157	Type VI secretion system effector, Hcp
ISU63_13125	COG2723	6-phospho-beta-galactosidase activity
ISU63_13130	COG1737	Transcriptional regulator
ISU63_13150	COG3299	homolog of phage Mu protein gp47
ISU63_13190	COG4386	tail sheath protein
ISU63_13210	COG3622	Belongs to the hyi family
ISU63_13215	COG1349	DNA-binding transcription factor activity
ISU63_13225	COG3395	kinase activity
ISU63_13265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISU63_13290	COG2223	nitrite transmembrane transporter activity
ISU63_13295	COG0642	Histidine kinase
ISU63_13295	COG2198	Histidine kinase
ISU63_13300	COG0642	Histidine kinase
ISU63_13300	COG2198	Histidine kinase
ISU63_13310	COG2205	protein histidine kinase activity
ISU63_13310	COG0784	Response regulator, receiver
ISU63_13335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU63_13350	COG0814	amino acid
ISU63_13375	COG0697	spore germination
ISU63_13385	COG1982	Orn Lys Arg decarboxylase major
ISU63_13390	COG0531	amino acid
ISU63_13395	COG1174	glycine betaine transport
ISU63_13400	COG1125	glycine betaine transport
ISU63_13405	COG1174	glycine betaine transport
ISU63_13415	COG2897	thiosulfate sulfurtransferase activity
ISU63_13435	COG1122	ATPase activity
ISU63_13455	COG4807	Protein conserved in bacteria
ISU63_13470	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ISU63_13480	COG2261	transglycosylase associated protein
ISU63_13500	COG0277	FAD linked oxidase domain protein
ISU63_13505	COG1686	Belongs to the peptidase S11 family
ISU63_13515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU63_13540	COG3328	transposase activity
ISU63_13585	COG0517	IMP dehydrogenase activity
ISU63_13585	COG0516	GMP reductase activity
ISU63_13595	COG1645	bacterial-type flagellum-dependent swarming motility
ISU63_13610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU63_13615	COG2976	Protein conserved in bacteria
ISU63_13655	COG3468	outer membrane autotransporter barrel domain protein
ISU63_13660	COG3468	outer membrane autotransporter barrel domain protein
ISU63_13685	COG2975	iron-sulfur cluster assembly
ISU63_13690	COG0633	Ferredoxin
ISU63_13695	COG0443	Heat shock 70 kDa protein
ISU63_13710	COG0822	iron-sulfur transferase activity
ISU63_13715	COG1104	cysteine desulfurase activity
ISU63_13740	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU63_13745	COG3683	transport system, periplasmic component
ISU63_13750	COG3711	transcriptional antiterminator
ISU63_13755	COG2814	Major facilitator Superfamily
ISU63_13775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU63_13775	COG1017	nitric oxide dioxygenase activity
ISU63_13785	COG0347	Belongs to the P(II) protein family
ISU63_13790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU63_13790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ISU63_13795	COG2204	response regulator
ISU63_13800	COG3170	Tfp pilus assembly protein FimV
ISU63_13805	COG2205	protein histidine kinase activity
ISU63_13850	COG0560	Phosphoserine phosphatase
ISU63_13860	COG1737	Transcriptional regulator
ISU63_13865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU63_13880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ISU63_13915	COG3086	response to oxidative stress
ISU63_13920	COG3026	antisigma factor binding
ISU63_13935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ISU63_13945	COG0513	Belongs to the DEAD box helicase family
ISU63_13990	COG1984	allophanate hydrolase subunit 2
ISU63_14005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ISU63_14010	COG5212	phosphodiesterase
ISU63_14020	COG3272	Protein of unknown function (DUF1722)
ISU63_14055	COG2205	protein histidine kinase activity
ISU63_14060	COG0745	RESPONSE REGULATOR receiver
ISU63_14075	COG0033	Phosphoglucomutase
ISU63_14080	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ISU63_14095	COG1917	Cupin 2, conserved barrel domain protein
ISU63_14095	COG2169	Transcriptional regulator
ISU63_14100	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISU63_14105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU63_14110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU63_14120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU63_14130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU63_14140	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU63_14145	COG4413	Urea transporter
ISU63_14155	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ISU63_14180	COG0831	urea catabolic process
ISU63_14185	COG1124	(ABC) transporter
ISU63_14190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ISU63_14195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU63_14205	COG0747	negative chemotaxis
ISU63_14210	COG1278	Cold shock
ISU63_14250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ISU63_14255	COG4175	Glycine betaine
ISU63_14260	COG4176	ABC-type proline glycine betaine transport system permease component
ISU63_14265	COG2113	Glycine betaine
ISU63_14300	COG0582	viral genome integration into host DNA
ISU63_14310	COG0596	Alpha beta hydrolase
ISU63_14325	COG0735	belongs to the Fur family
ISU63_14350	COG1263	PTS System
ISU63_14350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU63_14350	COG2190	(PTS) system
ISU63_14360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ISU63_14365	COG1846	Transcriptional regulator
ISU63_14365	COG1940	carbohydrate kinase activity
ISU63_14370	COG0647	UMP catabolic process
ISU63_14375	COG0367	asparagine synthase
ISU63_14410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU63_14415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ISU63_14420	COG1702	phosphate starvation-inducible protein PhoH
ISU63_14430	COG4535	Mg2 and Co2 transporter CorC
ISU63_14435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ISU63_14445	COG0765	amino acid transport
ISU63_14450	COG0765	amino acid transport
ISU63_14455	COG1126	abc transporter atp-binding protein
ISU63_14460	COG2888	peptidyl-tyrosine sulfation
ISU63_14475	COG1466	dna polymerase III delta subunit
ISU63_14485	COG0799	negative regulation of ribosome biogenesis
ISU63_14495	COG0768	penicillin binding
ISU63_14500	COG0772	Belongs to the SEDS family
ISU63_14505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU63_14510	COG1686	Belongs to the peptidase S11 family
ISU63_14530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU63_14535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU63_14545	COG1278	Cold shock
ISU63_14550	COG2197	response regulator
ISU63_14575	COG5265	(ABC) transporter
ISU63_14585	COG3718	enzyme involved in inositol metabolism
ISU63_14595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU63_14600	COG0673	inositol 2-dehydrogenase activity
ISU63_14605	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_14610	COG1129	ABC transporter
ISU63_14625	COG3962	Belongs to the TPP enzyme family
ISU63_14645	COG2373	Large extracellular alpha-helical protein
ISU63_14655	COG4953	penicillin-binding protein 1C
ISU63_14660	COG3423	Transcriptional regulator
ISU63_14715	COG3328	transposase activity
ISU63_14730	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU63_14740	COG0656	L-ascorbic acid biosynthetic process
ISU63_14745	COG0667	Aldo Keto reductase
ISU63_14775	COG0671	phosphoesterase, PA-phosphatase related
ISU63_14775	COG2453	phosphatase
ISU63_14780	COG2267	carboxylic ester hydrolase activity
ISU63_14790	COG4589	Belongs to the CDS family
ISU63_14795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ISU63_14805	COG0582	viral genome integration into host DNA
ISU63_14840	COG2501	S4 domain
ISU63_14855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU63_14865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ISU63_14870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ISU63_14875	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ISU63_14880	COG4181	ATPase activity
ISU63_14885	COG2755	lipolytic protein G-D-S-L family
ISU63_14890	COG0300	oxidoreductase activity
ISU63_14895	COG3118	belongs to the thioredoxin family
ISU63_14900	COG0330	HflC and HflK could
ISU63_14905	COG1585	Membrane protein implicated in regulation of membrane protease activity
ISU63_14910	COG0789	Transcriptional regulator
ISU63_14915	COG2217	Heavy metal translocating P-type atpase
ISU63_14920	COG3735	TraB family
ISU63_14925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISU63_14940	COG2223	nitrite transmembrane transporter activity
ISU63_14945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU63_14945	COG4651	solute:proton antiporter activity
ISU63_14950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU63_14955	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU63_14975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU63_15015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU63_15035	COG0543	2 iron, 2 sulfur cluster binding
ISU63_15035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU63_15065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ISU63_15075	COG2832	Protein of unknown function (DUF454)
ISU63_15090	COG1196	nuclear chromosome segregation
ISU63_15090	COG3264	Mechanosensitive ion channel
ISU63_15095	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ISU63_15100	COG1309	transcriptional regulator
ISU63_15105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU63_15110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU63_15120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU63_15145	COG3695	enzyme binding
ISU63_15150	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ISU63_15155	COG1946	Acyl-CoA thioesterase
ISU63_15160	COG0004	ammonium transporteR
ISU63_15165	COG0347	Belongs to the P(II) protein family
ISU63_15170	COG1132	(ABC) transporter
ISU63_15175	COG1132	(ABC) transporter
ISU63_15180	COG1522	sequence-specific DNA binding
ISU63_15195	COG4533	DNA binding
ISU63_15205	COG0824	Thioesterase
ISU63_15210	COG1555	photosystem II stabilization
ISU63_15215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU63_15220	COG0776	regulation of translation
ISU63_15225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ISU63_15245	COG0271	Belongs to the BolA IbaG family
ISU63_15250	COG3056	Lipoprotein
ISU63_15255	COG2223	nitrite transmembrane transporter activity
ISU63_15265	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ISU63_15270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ISU63_15275	COG1845	cytochrome c oxidase, subunit III
ISU63_15280	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ISU63_15290	COG2814	Major facilitator Superfamily
ISU63_15300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISU63_15305	COG0693	protein deglycase activity
ISU63_15320	COG0142	geranyltranstransferase activity
ISU63_15335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ISU63_15340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ISU63_15355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU63_15355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU63_15380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU63_15385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU63_15390	COG1862	Preprotein translocase
ISU63_15410	COG0450	alkyl hydroperoxide reductase
ISU63_15430	COG0366	Alpha amylase catalytic
ISU63_15450	COG5002	protein histidine kinase activity
ISU63_15455	COG0745	RESPONSE REGULATOR receiver
ISU63_15460	COG0420	3'-5' exonuclease activity
ISU63_15465	COG0419	ATPase involved in DNA repair
ISU63_15470	COG1940	carbohydrate kinase activity
ISU63_15505	COG2226	methyltransferase
ISU63_15565	COG0583	DNA-binding transcription factor activity
ISU63_15570	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU63_15590	COG1477	protein flavinylation
ISU63_15610	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU63_15615	COG1805	sodium ion transport
ISU63_15625	COG3034	peptidoglycan biosynthetic process
ISU63_15630	COG0121	glutamine amidotransferase
ISU63_15640	COG1960	acyl-CoA dehydrogenase activity
ISU63_15650	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ISU63_15675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU63_15685	COG0765	amino acid transport
ISU63_15720	COG2814	Major facilitator Superfamily
ISU63_15725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ISU63_15735	COG1846	Transcriptional regulator
ISU63_15740	COG1566	PFAM secretion protein HlyD family protein
ISU63_15745	COG2814	Major facilitator Superfamily
ISU63_15750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU63_15755	COG3118	belongs to the thioredoxin family
ISU63_15760	COG3148	PFAM DTW domain containing protein
ISU63_15765	COG1042	CoA-binding domain protein
ISU63_15765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU63_15765	COG0045	succinate-CoA ligase (ADP-forming) activity
ISU63_15770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISU63_15775	COG5544	Lipoprotein
ISU63_15805	COG0542	response to heat
ISU63_15815	COG0564	pseudouridine synthase activity
ISU63_15820	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU63_15825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISU63_15855	COG0287	Prephenate dehydrogenase
ISU63_15855	COG1605	Chorismate mutase
ISU63_15860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU63_15865	COG3279	Response regulator of the LytR AlgR family
ISU63_15875	COG3137	Salt-induced outer membrane protein
ISU63_15905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ISU63_15910	COG4137	Cytochrome C assembly protein
ISU63_15915	COG4536	flavin adenine dinucleotide binding
ISU63_15935	COG2918	glutathione biosynthetic process
ISU63_15940	COG1238	metal cluster binding
ISU63_15945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU63_15980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ISU63_16020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU63_16025	COG3958	Transketolase
ISU63_16030	COG3959	Transketolase, thiamine diphosphate binding domain
ISU63_16035	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_16040	COG1129	ABC transporter
ISU63_16050	COG1879	ABC-type sugar transport system periplasmic component
ISU63_16060	COG3783	Cytochrome b(562)
ISU63_16065	COG3038	cytochrome b561
ISU63_16070	COG3381	protein complex oligomerization
ISU63_16075	COG3302	dmso reductase anchor subunit
ISU63_16080	COG0437	4 iron, 4 sulfur cluster binding
ISU63_16085	COG0243	molybdopterin cofactor binding
ISU63_16090	COG0235	Class ii aldolase
ISU63_16095	COG1349	DNA-binding transcription factor activity
ISU63_16110	COG1129	ABC transporter
ISU63_16115	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_16120	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_16125	COG3623	hexulose-6-phosphate isomerase
ISU63_16130	COG1070	Carbohydrate kinase
ISU63_16135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU63_16135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU63_16145	COG0024	Methionine aminopeptidase
ISU63_16155	COG4771	TonB-dependent receptor
ISU63_16165	COG1858	cytochrome C peroxidase
ISU63_16170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_16190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISU63_16205	COG2376	Dihydroxyacetone kinase
ISU63_16210	COG1028	Short-chain dehydrogenase reductase Sdr
ISU63_16215	COG1063	alcohol dehydrogenase
ISU63_16220	COG0698	ribose 5-phosphate isomerase
ISU63_16230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISU63_16235	COG4942	peptidase
ISU63_16235	COG1388	LysM domain
ISU63_16275	COG0529	Catalyzes the synthesis of activated sulfate
ISU63_16330	COG0720	synthase
ISU63_16335	COG0602	queuosine metabolic process
ISU63_16355	COG3956	TIGRFAM MazG family protein
ISU63_16360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU63_16365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ISU63_16375	COG2205	protein histidine kinase activity
ISU63_16375	COG3437	response regulator, receiver
ISU63_16375	COG3850	Histidine kinase
ISU63_16375	COG4999	Histidine kinase
ISU63_16380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU63_16400	COG2860	membrane
ISU63_16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU63_16425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU63_16430	COG1120	ATPase activity
ISU63_16435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISU63_16440	COG1643	Atp-dependent helicase
ISU63_16445	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ISU63_16460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ISU63_16465	COG0617	tRNA 3'-terminal CCA addition
ISU63_16470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ISU63_16495	COG0842	Transport permease protein
ISU63_16500	COG1131	(ABC) transporter
ISU63_16505	COG0288	reversible hydration of carbon dioxide
ISU63_16510	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ISU63_16515	COG2132	Multicopper oxidase
ISU63_16535	COG0697	spore germination
ISU63_16545	COG1049	propionate catabolic process, 2-methylcitrate cycle
ISU63_16555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU63_16560	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU63_16565	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ISU63_16570	COG2186	Transcriptional regulator
ISU63_16575	COG1113	amino acid transport
ISU63_16580	COG3725	Membrane protein required for beta-lactamase induction
ISU63_16585	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU63_16595	COG4969	Belongs to the N-Me-Phe pilin family
ISU63_16600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU63_16605	COG1459	type II secretion system
ISU63_16655	COG0582	viral genome integration into host DNA
ISU63_16665	COG0795	lipopolysaccharide-transporting ATPase activity
ISU63_16670	COG0795	lipopolysaccharide-transporting ATPase activity
ISU63_16680	COG2927	DNA polymerase III (CHI subunit)
ISU63_16685	COG0525	valine-tRNA ligase activity
ISU63_16695	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ISU63_16705	COG2731	YhcH YjgK YiaL family protein
ISU63_16715	COG0601	transmembrane transport
ISU63_16720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU63_16725	COG0444	Belongs to the ABC transporter superfamily
ISU63_16730	COG4608	Belongs to the ABC transporter superfamily
ISU63_16745	COG2188	Transcriptional regulator
ISU63_16750	COG3624	Phosphonate C-P lyase system protein PhnG
ISU63_16755	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ISU63_16760	COG3626	phosphonate metabolism
ISU63_16765	COG3627	carbon phosphorus lyase activity
ISU63_16770	COG4107	phosphonate C-P lyase system protein PhnK
ISU63_16775	COG4778	phosphonate C-P lyase system protein PhnL
ISU63_16780	COG3454	Phosphonate metabolism
ISU63_16785	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ISU63_16790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ISU63_16795	COG0702	epimerase
ISU63_16810	COG3842	ATPase activity
ISU63_16815	COG0395	ABC-type sugar transport system, permease component
ISU63_16820	COG1175	transmembrane transport
ISU63_16825	COG1653	transport
ISU63_16845	COG3153	acetyltransferase
ISU63_16850	COG3154	lipid carrier protein
ISU63_16855	COG0826	peptidase U32
ISU63_16860	COG0826	peptidase U32
ISU63_16870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU63_16880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISU63_16900	COG0513	Belongs to the DEAD box helicase family
ISU63_16930	COG3710	Transcriptional regulator
ISU63_16950	COG1256	bacterial-type flagellum assembly
ISU63_16960	COG1706	bacterial-type flagellum-dependent cell motility
ISU63_16970	COG4786	Flagellar basal body rod
ISU63_16975	COG4787	bacterial-type flagellum-dependent cell motility
ISU63_16980	COG1749	Flagellar hook protein flgE
ISU63_16985	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ISU63_16990	COG1558	bacterial-type flagellum-dependent cell motility
ISU63_16995	COG1815	bacterial-type flagellum-dependent cell motility
ISU63_17000	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ISU63_17040	COG1677	Flagellar hook-basal body complex protein FliE
ISU63_17065	COG1987	bacterial-type flagellum assembly
ISU63_17070	COG1684	flagellar biosynthetic protein fliR
ISU63_17075	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU63_17095	COG4592	Periplasmic binding protein
ISU63_17130	COG4964	Belongs to the GSP D family
ISU63_17135	COG4964	Belongs to the GSP D family
ISU63_17185	COG0848	biopolymer transport protein
ISU63_17190	COG0811	peptide transport
ISU63_17195	COG0626	cystathionine gamma-synthase activity
ISU63_17200	COG0586	Pfam SNARE associated Golgi protein
ISU63_17205	COG2207	Transcriptional regulator
ISU63_17210	COG1979	alcohol dehydrogenase
ISU63_17220	COG0656	L-ascorbic acid biosynthetic process
ISU63_17230	COG2132	Multicopper oxidase
ISU63_17240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ISU63_17250	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISU63_17255	COG0583	DNA-binding transcription factor activity
ISU63_17265	COG3150	esterase
ISU63_17270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ISU63_17275	COG3151	Protein conserved in bacteria
ISU63_17280	COG0494	nUDIX hydrolase
ISU63_17285	COG1538	Outer membrane efflux protein
ISU63_17295	COG0754	glutathionylspermidine amidase activity
ISU63_17300	COG3384	dioxygenase
ISU63_17320	COG0531	amino acid
ISU63_17335	COG3025	triphosphatase activity
ISU63_17340	COG4991	sh3 domain protein
ISU63_17355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISU63_17370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ISU63_17375	COG0358	DNA primase activity
ISU63_17445	COG0251	oxidation-reduction process
ISU63_17465	COG0436	Aminotransferase
ISU63_17485	COG1289	transmembrane transporter activity
ISU63_17505	COG0395	ABC-type sugar transport system, permease component
ISU63_17515	COG2182	Extracellular solute-binding protein
ISU63_17520	COG1609	Transcriptional regulator
ISU63_17525	COG3459	Glycosyltransferase 36 associated
ISU63_17530	COG3842	ATPase activity
ISU63_17550	COG3210	domain, Protein
ISU63_17555	COG3210	domain, Protein
ISU63_17585	COG3210	domain, Protein
ISU63_17590	COG2831	hemolysin activation secretion protein
ISU63_17595	COG4245	von Willebrand factor, type A
ISU63_17610	COG4245	von Willebrand factor, type A
ISU63_17625	COG3247	response to pH
ISU63_17630	COG0446	pyridine nucleotide-disulphide oxidoreductase
ISU63_17630	COG1902	pentaerythritol trinitrate reductase activity
ISU63_17645	COG1451	nucleotide metabolic process
ISU63_17650	COG0673	inositol 2-dehydrogenase activity
ISU63_17670	COG2721	sulfolactate sulfo-lyase activity
ISU63_17685	COG2271	Major facilitator Superfamily
ISU63_17700	COG0586	Pfam SNARE associated Golgi protein
ISU63_17715	COG4575	ribosome binding
ISU63_17720	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ISU63_17730	COG2259	Doxx family
ISU63_17750	COG0494	nUDIX hydrolase
ISU63_17780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ISU63_17785	COG0849	cell division
ISU63_17790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ISU63_17810	COG0772	Belongs to the SEDS family
ISU63_17825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ISU63_17830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ISU63_17835	COG0768	penicillin binding
ISU63_17840	COG3116	cell division
ISU63_17865	COG1609	Transcriptional regulator
ISU63_17880	COG0028	Belongs to the TPP enzyme family
ISU63_17885	COG1022	Amp-dependent synthetase and ligase
ISU63_17915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISU63_17920	COG1280	lysine exporter protein (LysE YggA)
ISU63_17925	COG2966	Psort location CytoplasmicMembrane, score
ISU63_17935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ISU63_17985	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ISU63_17990	COG0564	pseudouridine synthase activity
ISU63_18075	COG2885	chlorophyll binding
ISU63_18075	COG3047	cAMP biosynthetic process
ISU63_18095	COG0417	DNA replication proofreading
ISU63_18100	COG0586	Pfam SNARE associated Golgi protein
ISU63_18105	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ISU63_18110	COG1178	ABC-type Fe3 transport system permease component
ISU63_18115	COG4143	(ABC) transporter
ISU63_18125	COG2814	Major facilitator Superfamily
ISU63_18140	COG0473	3-isopropylmalate dehydrogenase activity
ISU63_18160	COG1047	Peptidyl-prolyl cis-trans
ISU63_18175	COG0196	riboflavin kinase activity
ISU63_18185	COG0583	DNA-binding transcription factor activity
ISU63_18205	COG1584	GPR1 FUN34 yaaH family protein
ISU63_18220	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISU63_18260	COG0745	RESPONSE REGULATOR receiver
ISU63_18265	COG3045	CreA protein
ISU63_18270	COG2207	Transcriptional regulator
ISU63_18270	COG3708	Transcriptional regulator
ISU63_18285	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ISU63_18290	COG0741	lytic transglycosylase activity
ISU63_18305	COG2199	diguanylate cyclase activity
ISU63_18310	COG2885	chlorophyll binding
ISU63_18335	COG0560	Phosphoserine phosphatase
ISU63_18340	COG3726	membrane protein affecting hemolysin expression
ISU63_18365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU63_18370	COG0084	hydrolase, TatD family'
ISU63_18375	COG4667	esterase of the alpha-beta hydrolase superfamily
ISU63_18385	COG2823	Periplasmic or secreted lipoprotein
ISU63_18395	COG0456	acetyltransferase
ISU63_18400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ISU63_18440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU63_18445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU63_18460	COG0859	PFAM glycosyl transferase family 9
ISU63_18465	COG1070	Carbohydrate kinase
ISU63_18510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU63_18510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU63_18510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU63_18515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU63_18520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU63_18525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU63_18530	COG2207	Transcriptional regulator
ISU63_18540	COG4269	membrane
ISU63_18595	COG1401	restriction endodeoxyribonuclease activity
ISU63_18620	COG1011	Hydrolase
ISU63_18630	COG0174	glutamine synthetase
ISU63_18635	COG3852	Histidine kinase
ISU63_18645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU63_18670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU63_18670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU63_18675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU63_18680	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ISU63_18685	COG3084	Protein conserved in bacteria
ISU63_18695	COG1763	Mo-molybdopterin cofactor biosynthetic process
ISU63_18700	COG3328	transposase activity
ISU63_18740	COG0583	DNA-binding transcription factor activity
ISU63_18745	COG1741	Belongs to the pirin family
ISU63_18755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ISU63_18775	COG2823	Periplasmic or secreted lipoprotein
ISU63_18785	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ISU63_18790	COG0784	Response regulator, receiver
ISU63_18790	COG2198	Histidine kinase
ISU63_18790	COG5002	protein histidine kinase activity
ISU63_18795	COG1242	4 iron, 4 sulfur cluster binding
ISU63_18800	COG0070	glutamate synthase
ISU63_18800	COG0067	glutamate synthase
ISU63_18800	COG0069	glutamate synthase activity
ISU63_18805	COG0493	'glutamate synthase
ISU63_18815	COG2969	positive regulation of protein catabolic process
ISU63_18820	COG0625	glutathione transferase activity
ISU63_18840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISU63_18845	COG3105	Protein conserved in bacteria
ISU63_18850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU63_18860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU63_18870	COG5007	Belongs to the BolA IbaG family
ISU63_18875	COG3113	response to antibiotic
ISU63_18880	COG2854	intermembrane phospholipid transfer
ISU63_18885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU63_18890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ISU63_18895	COG1127	ABC transporter
ISU63_18900	COG0530	calcium, potassium:sodium antiporter activity
ISU63_18905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISU63_18905	COG0517	IMP dehydrogenase activity
ISU63_18910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ISU63_18915	COG3117	lipopolysaccharide transmembrane transporter activity
ISU63_18920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ISU63_18925	COG1137	ATPase activity
ISU63_18930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ISU63_18950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU63_18975	COG1609	Transcriptional regulator
ISU63_18980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU63_18980	COG1263	PTS System
ISU63_18985	COG0366	Alpha amylase catalytic
ISU63_18990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU63_18995	COG3783	Cytochrome b(562)
ISU63_19005	COG0312	modulator of DNA gyrase
ISU63_19015	COG2732	(Barnase) inhibitor
ISU63_19045	COG0583	DNA-binding transcription factor activity
ISU63_19095	COG0312	modulator of DNA gyrase
ISU63_19100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU63_19105	COG3164	Protein of unknown function
ISU63_19110	COG1530	ribonuclease E activity
ISU63_19115	COG0424	maF-like protein
ISU63_19120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ISU63_19125	COG1792	Involved in formation and maintenance of cell shape
ISU63_19130	COG1077	Cell shape determining protein MreB Mrl
ISU63_19135	COG2199	diguanylate cyclase activity
ISU63_19135	COG2200	EAL domain
ISU63_19140	COG0604	alcohol dehydrogenase
ISU63_19145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ISU63_19160	COG0511	ligase activity, forming carbon-carbon bonds
ISU63_19165	COG0439	Biotin carboxylase
ISU63_19175	COG3924	membrane
ISU63_19180	COG4145	pantothenate transmembrane transporter activity
ISU63_19190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU63_19195	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ISU63_19225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU63_19235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU63_19240	COG3133	Outer membrane lipoprotein
ISU63_19245	COG1278	Cold shock
ISU63_19250	COG1278	Cold shock
ISU63_19270	COG0625	glutathione transferase activity
ISU63_19280	COG1069	ribulokinase activity
ISU63_19290	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_19295	COG1129	ABC transporter
ISU63_19305	COG1560	Kdo2-lipid A biosynthetic process
ISU63_19315	COG0025	NhaP-type Na H and K H
ISU63_19320	COG2252	PERMEase
ISU63_19325	COG3077	Addiction module antitoxin, RelB DinJ family
ISU63_19340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU63_19350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISU63_19355	COG0431	NADPH-dependent FMN reductase
ISU63_19360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ISU63_19365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU63_19370	COG1869	D-ribose catabolic process
ISU63_19375	COG2207	Transcriptional regulator
ISU63_19375	COG1917	Cupin 2, conserved barrel domain protein
ISU63_19400	COG3209	COG3209 Rhs family protein
ISU63_19410	COG3501	Rhs element vgr protein
ISU63_19455	COG3501	Rhs element vgr protein
ISU63_19545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU63_19550	COG0058	SHG alpha-glucan phosphorylase activity
ISU63_19575	COG3275	phosphorelay sensor kinase activity
ISU63_19610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU63_19615	COG2095	MarC family integral membrane protein
ISU63_19630	COG3265	gluconokinase activity
ISU63_19635	COG2610	gluconate transmembrane transporter activity
ISU63_19640	COG1609	Transcriptional regulator
ISU63_19645	COG1741	Belongs to the pirin family
ISU63_19665	COG0191	fructose-bisphosphate aldolase activity
ISU63_19680	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU63_19695	COG2081	HI0933 family
ISU63_19700	COG0306	phosphate transporter
ISU63_19715	COG0589	response to stress
ISU63_19735	COG0339	signal peptide processing
ISU63_19740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ISU63_19745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU63_19750	COG3835	regulator
ISU63_19760	COG2610	gluconate transmembrane transporter activity
ISU63_19765	COG1929	Belongs to the glycerate kinase type-1 family
ISU63_19790	COG1295	ribonuclease BN
ISU63_19795	COG2134	cdp-diacylglycerol pyrophosphatase
ISU63_19800	COG2982	Protein involved in outer membrane biogenesis
ISU63_19805	COG2200	EAL domain
ISU63_19810	COG1942	4-Oxalocrotonate Tautomerase
ISU63_19815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU63_19820	COG0612	Peptidase, M16
ISU63_19840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU63_19845	COG2199	diguanylate cyclase activity
ISU63_19845	COG2200	EAL domain
ISU63_19850	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ISU63_19855	COG4608	Belongs to the ABC transporter superfamily
ISU63_19860	COG0444	Belongs to the ABC transporter superfamily
ISU63_19865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU63_19870	COG0601	transmembrane transport
ISU63_19875	COG0747	negative chemotaxis
ISU63_19880	COG2831	hemolysin activation secretion protein
ISU63_19900	COG2271	Major facilitator Superfamily
ISU63_19925	COG2197	response regulator
ISU63_19930	COG2194	sulfuric ester hydrolase activity
ISU63_19945	COG2986	histidine ammonia-lyase
ISU63_19975	COG4607	ABC-type enterochelin transport system periplasmic component
ISU63_19985	COG4605	iron ion homeostasis
ISU63_19990	COG4604	ABC transporter, ATP-binding protein
ISU63_20035	COG0582	viral genome integration into host DNA
ISU63_20045	COG2207	Transcriptional regulator
ISU63_20045	COG1609	Transcriptional regulator
ISU63_20050	COG4214	carbohydrate transport
ISU63_20060	COG4213	ABC transporter substrate-binding protein
ISU63_20070	COG1070	Carbohydrate kinase
ISU63_20080	COG3121	Chaperone
ISU63_20095	COG3274	enterobacterial common antigen metabolic process
ISU63_20165	COG1175	transmembrane transport
ISU63_20170	COG3833	ABC-type maltose transport systems, permease component
ISU63_20185	COG0527	aspartate kinase activity
ISU63_20215	COG2224	Isocitrate lyase
ISU63_20220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ISU63_20260	COG2186	Transcriptional regulator
ISU63_20265	COG0477	Major facilitator Superfamily
ISU63_20280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU63_20310	COG1522	sequence-specific DNA binding
ISU63_20315	COG0716	FMN binding
ISU63_20330	COG3312	ion transport
ISU63_20385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ISU63_20390	COG0573	inorganic phosphate transmembrane transporter activity
ISU63_20395	COG0581	inorganic phosphate transmembrane transporter activity
ISU63_20405	COG0704	Plays a role in the regulation of phosphate uptake
ISU63_20415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU63_20420	COG0765	amino acid transport
ISU63_20425	COG0765	amino acid transport
ISU63_20430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU63_20440	COG2252	PERMEase
ISU63_20470	COG0706	membrane insertase activity
ISU63_20485	COG0230	Belongs to the bacterial ribosomal protein bL34 family