locus-tag	class	description
ISU61_00010	COG0592	DNA-directed DNA polymerase activity
ISU61_00025	COG0187	DNA topoisomerase II activity
ISU61_00030	COG0561	phosphatase activity
ISU61_00040	COG2423	ornithine cyclodeaminase activity
ISU61_00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISU61_00055	COG5645	(Lipo)protein
ISU61_00075	COG3977	Valine--pyruvate aminotransferase
ISU61_00085	COG0366	Alpha amylase catalytic
ISU61_00100	COG2885	chlorophyll binding
ISU61_00110	COG2818	Glycosylase
ISU61_00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU61_00135	COG2213	PTS system mannitol-specific
ISU61_00145	COG3722	fumarate hydratase activity
ISU61_00170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ISU61_00185	COG0437	4 iron, 4 sulfur cluster binding
ISU61_00190	COG2864	formate dehydrogenase
ISU61_00205	COG3276	selenocysteine insertion sequence binding
ISU61_00250	COG3274	enterobacterial common antigen metabolic process
ISU61_00265	COG3121	Chaperone
ISU61_00275	COG1070	Carbohydrate kinase
ISU61_00285	COG4213	ABC transporter substrate-binding protein
ISU61_00295	COG4214	carbohydrate transport
ISU61_00300	COG1609	Transcriptional regulator
ISU61_00300	COG2207	Transcriptional regulator
ISU61_00310	COG0582	viral genome integration into host DNA
ISU61_00355	COG4604	ABC transporter, ATP-binding protein
ISU61_00360	COG4605	iron ion homeostasis
ISU61_00370	COG4607	ABC-type enterochelin transport system periplasmic component
ISU61_00400	COG2986	histidine ammonia-lyase
ISU61_00435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISU61_00460	COG1739	Uncharacterized protein family UPF0029
ISU61_00465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ISU61_00470	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ISU61_00495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ISU61_00545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU61_00550	COG0058	SHG alpha-glucan phosphorylase activity
ISU61_00575	COG3275	phosphorelay sensor kinase activity
ISU61_00610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU61_00615	COG2095	MarC family integral membrane protein
ISU61_00630	COG3265	gluconokinase activity
ISU61_00635	COG2610	gluconate transmembrane transporter activity
ISU61_00640	COG1609	Transcriptional regulator
ISU61_00645	COG1741	Belongs to the pirin family
ISU61_00665	COG0191	fructose-bisphosphate aldolase activity
ISU61_00680	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_00695	COG2081	HI0933 family
ISU61_00700	COG0306	phosphate transporter
ISU61_00715	COG0589	response to stress
ISU61_00735	COG0339	signal peptide processing
ISU61_00740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ISU61_00745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU61_00750	COG3835	regulator
ISU61_00760	COG2610	gluconate transmembrane transporter activity
ISU61_00765	COG1929	Belongs to the glycerate kinase type-1 family
ISU61_00790	COG1295	ribonuclease BN
ISU61_00795	COG2134	cdp-diacylglycerol pyrophosphatase
ISU61_00800	COG2982	Protein involved in outer membrane biogenesis
ISU61_00805	COG2200	EAL domain
ISU61_00810	COG1942	4-Oxalocrotonate Tautomerase
ISU61_00815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU61_00820	COG0612	Peptidase, M16
ISU61_00840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU61_00845	COG2199	diguanylate cyclase activity
ISU61_00845	COG2200	EAL domain
ISU61_00850	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ISU61_00855	COG4608	Belongs to the ABC transporter superfamily
ISU61_00860	COG0444	Belongs to the ABC transporter superfamily
ISU61_00865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU61_00870	COG0601	transmembrane transport
ISU61_00875	COG0747	negative chemotaxis
ISU61_00880	COG2831	hemolysin activation secretion protein
ISU61_00895	COG2271	Major facilitator Superfamily
ISU61_00900	COG3851	Histidine kinase
ISU61_00905	COG2197	response regulator
ISU61_00910	COG2194	sulfuric ester hydrolase activity
ISU61_00940	COG1349	DNA-binding transcription factor activity
ISU61_00960	COG0058	SHG alpha-glucan phosphorylase activity
ISU61_00965	COG0058	SHG alpha-glucan phosphorylase activity
ISU61_00970	COG1640	4-alpha-glucanotransferase
ISU61_01005	COG1918	ferrous iron import across plasma membrane
ISU61_01010	COG2183	response to ionizing radiation
ISU61_01015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU61_01040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ISU61_01045	COG1011	Hydrolase
ISU61_01055	COG0494	nUDIX hydrolase
ISU61_01060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ISU61_01085	COG4796	Type ii and iii secretion system protein
ISU61_01110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISU61_01115	COG0546	phosphoglycolate phosphatase activity
ISU61_01120	COG0180	Tryptophanyl-tRNA synthetase
ISU61_01140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISU61_01145	COG0402	S-adenosylhomocysteine deaminase activity
ISU61_01165	COG1486	melibiose metabolic process
ISU61_01170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU61_01175	COG0433	COG0433 Predicted ATPase
ISU61_01190	COG1289	transmembrane transporter activity
ISU61_01200	COG1765	OsmC-like protein
ISU61_01210	COG3954	Phosphoribulokinase
ISU61_01220	COG0429	hydrolase of the alpha beta-hydrolase fold
ISU61_01230	COG4521	taurine ABC transporter
ISU61_01240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU61_01245	COG2175	clavaminate synthase activity
ISU61_01255	COG1216	Glycosyl transferase, family 2
ISU61_01275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ISU61_01280	COG1047	Peptidyl-prolyl cis-trans
ISU61_01290	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU61_01295	COG2964	Protein conserved in bacteria
ISU61_01315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ISU61_01320	COG0049	tRNA binding
ISU61_01350	COG0051	transcription antitermination factor activity, RNA binding
ISU61_01365	COG0089	rRNA binding
ISU61_01375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ISU61_01385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ISU61_01390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ISU61_01400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ISU61_01405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ISU61_01445	COG1841	ribosomal large subunit assembly
ISU61_01455	COG0201	protein transport
ISU61_01460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU61_01475	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ISU61_01490	COG0789	Transcriptional regulator
ISU61_01495	COG3036	rescue of stalled ribosome
ISU61_01525	COG0758	DNA mediated transformation
ISU61_01535	COG0551	DNA topoisomerase type I activity
ISU61_01550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISU61_01605	COG3162	membrane
ISU61_01725	COG2391	methyltransferase activity
ISU61_01730	COG0425	Belongs to the sulfur carrier protein TusA family
ISU61_01735	COG0583	DNA-binding transcription factor activity
ISU61_01740	COG0814	amino acid
ISU61_01745	COG0626	cystathionine gamma-synthase activity
ISU61_01755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU61_01760	COG4558	Periplasmic binding protein
ISU61_01765	COG3720	iron ion transport
ISU61_01770	COG4771	TonB-dependent receptor
ISU61_01780	COG0702	epimerase
ISU61_01785	COG3721	Heme iron utilization protein
ISU61_01810	COG1358	cellular component organization or biogenesis
ISU61_01870	COG3121	Chaperone
ISU61_01910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ISU61_01920	COG0735	belongs to the Fur family
ISU61_01925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU61_01950	COG1448	Aminotransferase
ISU61_01955	COG2315	Protein conserved in bacteria
ISU61_01960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ISU61_01965	COG0629	single-stranded DNA binding
ISU61_01975	COG1454	alcohol dehydrogenase
ISU61_02035	COG1309	transcriptional regulator
ISU61_02040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU61_02040	COG0493	'glutamate synthase
ISU61_02045	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU61_02050	COG3383	formate dehydrogenase (NAD+) activity
ISU61_02065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISU61_02110	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ISU61_02120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISU61_02125	COG1053	succinate dehydrogenase
ISU61_02140	COG1511	domain protein
ISU61_02140	COG3264	Mechanosensitive ion channel
ISU61_02155	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ISU61_02170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ISU61_02175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ISU61_02175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ISU61_02180	COG0802	atpase or kinase
ISU61_02185	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU61_02205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ISU61_02210	COG0330	HflC and HflK could
ISU61_02215	COG0330	HflC and HflK could
ISU61_02220	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ISU61_02235	COG0557	exoribonuclease II activity
ISU61_02240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU61_02245	COG1960	acyl-CoA dehydrogenase activity
ISU61_02250	COG3650	response to hydrogen peroxide
ISU61_02255	COG1073	alpha beta
ISU61_02260	COG0360	Binds together with S18 to 16S ribosomal RNA
ISU61_02270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ISU61_02290	COG1605	Chorismate mutase
ISU61_02290	COG0077	Prephenate dehydratase
ISU61_02295	COG0287	Prephenate dehydrogenase
ISU61_02295	COG1605	Chorismate mutase
ISU61_02300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU61_02305	COG3279	Response regulator of the LytR AlgR family
ISU61_02315	COG3137	Salt-induced outer membrane protein
ISU61_02340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ISU61_02345	COG4137	Cytochrome C assembly protein
ISU61_02350	COG4536	flavin adenine dinucleotide binding
ISU61_02360	COG2918	glutathione biosynthetic process
ISU61_02365	COG1238	metal cluster binding
ISU61_02370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU61_02400	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ISU61_02440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU61_02445	COG3958	Transketolase
ISU61_02450	COG3959	Transketolase, thiamine diphosphate binding domain
ISU61_02455	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_02460	COG1129	ABC transporter
ISU61_02470	COG1879	ABC-type sugar transport system periplasmic component
ISU61_02480	COG3783	Cytochrome b(562)
ISU61_02485	COG3038	cytochrome b561
ISU61_02490	COG3381	protein complex oligomerization
ISU61_02495	COG3302	dmso reductase anchor subunit
ISU61_02500	COG0437	4 iron, 4 sulfur cluster binding
ISU61_02505	COG0243	molybdopterin cofactor binding
ISU61_02510	COG0235	Class ii aldolase
ISU61_02515	COG1349	DNA-binding transcription factor activity
ISU61_02525	COG1129	ABC transporter
ISU61_02530	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_02540	COG3623	hexulose-6-phosphate isomerase
ISU61_02545	COG1070	Carbohydrate kinase
ISU61_02550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU61_02550	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU61_02560	COG0024	Methionine aminopeptidase
ISU61_02570	COG4771	TonB-dependent receptor
ISU61_02580	COG3328	transposase activity
ISU61_02585	COG1858	cytochrome C peroxidase
ISU61_02590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU61_02610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISU61_02625	COG2376	Dihydroxyacetone kinase
ISU61_02630	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_02635	COG1063	alcohol dehydrogenase
ISU61_02640	COG0698	ribose 5-phosphate isomerase
ISU61_02650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISU61_02655	COG4942	peptidase
ISU61_02655	COG1388	LysM domain
ISU61_02695	COG0529	Catalyzes the synthesis of activated sulfate
ISU61_02750	COG0720	synthase
ISU61_02755	COG0602	queuosine metabolic process
ISU61_02775	COG3956	TIGRFAM MazG family protein
ISU61_02780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU61_02785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ISU61_02795	COG4999	Histidine kinase
ISU61_02795	COG2205	protein histidine kinase activity
ISU61_02795	COG3437	response regulator, receiver
ISU61_02795	COG3850	Histidine kinase
ISU61_02800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU61_02820	COG2860	membrane
ISU61_02840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU61_02845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU61_02850	COG1120	ATPase activity
ISU61_02855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISU61_02860	COG1643	Atp-dependent helicase
ISU61_02865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ISU61_02880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ISU61_02885	COG0617	tRNA 3'-terminal CCA addition
ISU61_02890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ISU61_02915	COG0842	Transport permease protein
ISU61_02920	COG1131	(ABC) transporter
ISU61_02925	COG0288	reversible hydration of carbon dioxide
ISU61_02930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ISU61_02935	COG2132	Multicopper oxidase
ISU61_02955	COG0697	spore germination
ISU61_02965	COG1049	propionate catabolic process, 2-methylcitrate cycle
ISU61_02975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU61_02980	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU61_02985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ISU61_02990	COG2186	Transcriptional regulator
ISU61_02995	COG1113	amino acid transport
ISU61_03000	COG3725	Membrane protein required for beta-lactamase induction
ISU61_03005	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU61_03015	COG4969	Belongs to the N-Me-Phe pilin family
ISU61_03020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU61_03025	COG1459	type II secretion system
ISU61_03075	COG3061	Opacity-associated protein A
ISU61_03080	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU61_03090	COG0737	Belongs to the 5'-nucleotidase family
ISU61_03100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ISU61_03110	COG1253	flavin adenine dinucleotide binding
ISU61_03120	COG0729	surface antigen
ISU61_03125	COG2911	Protein conserved in bacteria
ISU61_03130	COG2105	PFAM AIG2 family protein
ISU61_03135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ISU61_03140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ISU61_03145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ISU61_03165	COG3423	Transcriptional regulator
ISU61_03175	COG0142	geranyltranstransferase activity
ISU61_03190	COG0697	spore germination
ISU61_03200	COG0642	Histidine kinase
ISU61_03205	COG0745	RESPONSE REGULATOR receiver
ISU61_03210	COG2027	D-alanyl-D-alanine carboxypeptidase
ISU61_03220	COG1534	Rna-binding protein
ISU61_03235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ISU61_03245	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ISU61_03265	COG0195	Participates in both transcription termination and antitermination
ISU61_03310	COG0513	Belongs to the DEAD box helicase family
ISU61_03330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISU61_03340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU61_03350	COG0826	peptidase U32
ISU61_03355	COG0826	peptidase U32
ISU61_03360	COG3154	lipid carrier protein
ISU61_03365	COG3153	acetyltransferase
ISU61_03385	COG1653	transport
ISU61_03390	COG1175	transmembrane transport
ISU61_03395	COG0395	ABC-type sugar transport system, permease component
ISU61_03415	COG0702	epimerase
ISU61_03420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ISU61_03425	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ISU61_03430	COG3454	Phosphonate metabolism
ISU61_03435	COG4778	phosphonate C-P lyase system protein PhnL
ISU61_03440	COG4107	phosphonate C-P lyase system protein PhnK
ISU61_03445	COG3627	carbon phosphorus lyase activity
ISU61_03450	COG3626	phosphonate metabolism
ISU61_03455	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ISU61_03460	COG3624	Phosphonate C-P lyase system protein PhnG
ISU61_03465	COG2188	Transcriptional regulator
ISU61_03480	COG4608	Belongs to the ABC transporter superfamily
ISU61_03485	COG0444	Belongs to the ABC transporter superfamily
ISU61_03490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU61_03495	COG0601	transmembrane transport
ISU61_03505	COG2731	YhcH YjgK YiaL family protein
ISU61_03515	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ISU61_03525	COG0525	valine-tRNA ligase activity
ISU61_03530	COG2927	DNA polymerase III (CHI subunit)
ISU61_03540	COG0795	lipopolysaccharide-transporting ATPase activity
ISU61_03545	COG0795	lipopolysaccharide-transporting ATPase activity
ISU61_03555	COG0582	viral genome integration into host DNA
ISU61_03585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISU61_03590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU61_03595	COG0564	pseudouridine synthase activity
ISU61_03605	COG0542	response to heat
ISU61_03635	COG5544	Lipoprotein
ISU61_03640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISU61_03645	COG1042	CoA-binding domain protein
ISU61_03645	COG0045	succinate-CoA ligase (ADP-forming) activity
ISU61_03645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU61_03650	COG3148	PFAM DTW domain containing protein
ISU61_03655	COG3118	belongs to the thioredoxin family
ISU61_03660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU61_03665	COG2814	Major facilitator Superfamily
ISU61_03670	COG1566	PFAM secretion protein HlyD family protein
ISU61_03675	COG1846	Transcriptional regulator
ISU61_03685	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ISU61_03690	COG2814	Major facilitator Superfamily
ISU61_03725	COG0765	amino acid transport
ISU61_03735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU61_03765	COG3842	ATPase activity
ISU61_03770	COG0395	ABC-type sugar transport system, permease component
ISU61_03775	COG1175	transmembrane transport
ISU61_03785	COG0673	inositol 2-dehydrogenase activity
ISU61_03790	COG2188	Transcriptional regulator
ISU61_03910	COG2197	response regulator
ISU61_03920	COG3136	membrane protein required for alginate biosynthesis
ISU61_03940	COG1113	amino acid transport
ISU61_03960	COG2822	iron ion transport
ISU61_03965	COG0672	)-iron permease
ISU61_03980	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU61_03980	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU61_03980	COG0506	proline dehydrogenase activity
ISU61_03995	COG1126	abc transporter atp-binding protein
ISU61_04000	COG0765	amino acid transport
ISU61_04005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU61_04020	COG1191	sigma factor activity
ISU61_04050	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ISU61_04055	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ISU61_04060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ISU61_04080	COG1677	Flagellar hook-basal body complex protein FliE
ISU61_04100	COG1157	protein secretion by the type III secretion system
ISU61_04115	COG1580	Controls the rotational direction of flagella during chemotaxis
ISU61_04140	COG1987	bacterial-type flagellum assembly
ISU61_04160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU61_04165	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_04170	COG1129	ABC transporter
ISU61_04180	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_04185	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_04185	COG3347	Dehydrogenase
ISU61_04190	COG2390	Transcriptional regulator
ISU61_04200	COG1256	bacterial-type flagellum assembly
ISU61_04240	COG1558	bacterial-type flagellum-dependent cell motility
ISU61_04245	COG1815	bacterial-type flagellum-dependent cell motility
ISU61_04255	COG2747	anti-sigma28 factor FlgM
ISU61_04260	COG3418	PFAM FlgN family protein
ISU61_04285	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU61_04290	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU61_04315	COG2372	response to copper ion
ISU61_04320	COG1528	Iron-storage protein
ISU61_04335	COG1770	oligopeptidase
ISU61_04350	COG3141	response to X-ray
ISU61_04355	COG0513	Belongs to the DEAD box helicase family
ISU61_04380	COG1760	l-serine dehydratase
ISU61_04385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISU61_04390	COG2368	4-hydroxyphenylacetate
ISU61_04405	COG3971	2-oxopent-4-enoate hydratase activity
ISU61_04415	COG3384	dioxygenase
ISU61_04420	COG1012	belongs to the aldehyde dehydrogenase family
ISU61_04435	COG1846	Transcriptional regulator
ISU61_04440	COG1253	flavin adenine dinucleotide binding
ISU61_04445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU61_04445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU61_04450	COG3715	PTS system
ISU61_04455	COG3716	PTS system mannose fructose sorbose family IID component
ISU61_04495	COG0671	phosphoesterase, PA-phosphatase related
ISU61_04495	COG2453	phosphatase
ISU61_04500	COG2267	carboxylic ester hydrolase activity
ISU61_04510	COG4589	Belongs to the CDS family
ISU61_04515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ISU61_04525	COG0582	viral genome integration into host DNA
ISU61_04560	COG2501	S4 domain
ISU61_04575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU61_04585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ISU61_04590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ISU61_04595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ISU61_04600	COG4181	ATPase activity
ISU61_04605	COG2755	lipolytic protein G-D-S-L family
ISU61_04610	COG0300	oxidoreductase activity
ISU61_04615	COG3118	belongs to the thioredoxin family
ISU61_04620	COG0330	HflC and HflK could
ISU61_04625	COG1585	Membrane protein implicated in regulation of membrane protease activity
ISU61_04630	COG0789	Transcriptional regulator
ISU61_04635	COG2217	Heavy metal translocating P-type atpase
ISU61_04640	COG3735	TraB family
ISU61_04645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISU61_04660	COG2223	nitrite transmembrane transporter activity
ISU61_04665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU61_04665	COG4651	solute:proton antiporter activity
ISU61_04670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU61_04675	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU61_04695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU61_04735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU61_04755	COG0543	2 iron, 2 sulfur cluster binding
ISU61_04755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU61_04785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ISU61_04795	COG2832	Protein of unknown function (DUF454)
ISU61_04810	COG1196	nuclear chromosome segregation
ISU61_04810	COG3264	Mechanosensitive ion channel
ISU61_04815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ISU61_04820	COG1309	transcriptional regulator
ISU61_04825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU61_04830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU61_04840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU61_04865	COG3695	enzyme binding
ISU61_04870	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ISU61_04875	COG1946	Acyl-CoA thioesterase
ISU61_04880	COG0004	ammonium transporteR
ISU61_04885	COG0347	Belongs to the P(II) protein family
ISU61_04890	COG1132	(ABC) transporter
ISU61_04895	COG1132	(ABC) transporter
ISU61_04900	COG1522	sequence-specific DNA binding
ISU61_04915	COG4533	DNA binding
ISU61_04925	COG0824	Thioesterase
ISU61_04930	COG1555	photosystem II stabilization
ISU61_04935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU61_04940	COG0776	regulation of translation
ISU61_04945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ISU61_04965	COG0271	Belongs to the BolA IbaG family
ISU61_04970	COG3056	Lipoprotein
ISU61_04975	COG2223	nitrite transmembrane transporter activity
ISU61_04985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ISU61_04990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ISU61_04995	COG1845	cytochrome c oxidase, subunit III
ISU61_05000	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ISU61_05010	COG2814	Major facilitator Superfamily
ISU61_05020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISU61_05025	COG0693	protein deglycase activity
ISU61_05040	COG0142	geranyltranstransferase activity
ISU61_05055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ISU61_05060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ISU61_05075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU61_05075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU61_05100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU61_05105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU61_05110	COG1862	Preprotein translocase
ISU61_05130	COG0450	alkyl hydroperoxide reductase
ISU61_05150	COG0366	Alpha amylase catalytic
ISU61_05170	COG5002	protein histidine kinase activity
ISU61_05175	COG0745	RESPONSE REGULATOR receiver
ISU61_05180	COG0420	3'-5' exonuclease activity
ISU61_05185	COG0419	ATPase involved in DNA repair
ISU61_05190	COG1940	carbohydrate kinase activity
ISU61_05215	COG2226	methyltransferase
ISU61_05265	COG0583	DNA-binding transcription factor activity
ISU61_05270	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU61_05290	COG1477	protein flavinylation
ISU61_05310	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU61_05315	COG1805	sodium ion transport
ISU61_05325	COG3034	peptidoglycan biosynthetic process
ISU61_05330	COG0121	glutamine amidotransferase
ISU61_05340	COG1960	acyl-CoA dehydrogenase activity
ISU61_05350	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ISU61_05375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU61_05400	COG0582	viral genome integration into host DNA
ISU61_05410	COG0596	Alpha beta hydrolase
ISU61_05425	COG0735	belongs to the Fur family
ISU61_05450	COG2190	(PTS) system
ISU61_05450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU61_05450	COG1263	PTS System
ISU61_05460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ISU61_05465	COG1846	Transcriptional regulator
ISU61_05465	COG1940	carbohydrate kinase activity
ISU61_05470	COG0647	UMP catabolic process
ISU61_05475	COG0367	asparagine synthase
ISU61_05510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU61_05520	COG1702	phosphate starvation-inducible protein PhoH
ISU61_05530	COG4535	Mg2 and Co2 transporter CorC
ISU61_05535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ISU61_05545	COG0765	amino acid transport
ISU61_05550	COG0765	amino acid transport
ISU61_05555	COG1126	abc transporter atp-binding protein
ISU61_05560	COG2888	peptidyl-tyrosine sulfation
ISU61_05575	COG1466	dna polymerase III delta subunit
ISU61_05585	COG0799	negative regulation of ribosome biogenesis
ISU61_05595	COG0768	penicillin binding
ISU61_05600	COG0772	Belongs to the SEDS family
ISU61_05605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU61_05610	COG1686	Belongs to the peptidase S11 family
ISU61_05630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU61_05635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU61_05645	COG1278	Cold shock
ISU61_05650	COG2197	response regulator
ISU61_05675	COG5265	(ABC) transporter
ISU61_05685	COG3718	enzyme involved in inositol metabolism
ISU61_05695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU61_05700	COG0673	inositol 2-dehydrogenase activity
ISU61_05705	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_05710	COG1129	ABC transporter
ISU61_05725	COG3962	Belongs to the TPP enzyme family
ISU61_05745	COG2373	Large extracellular alpha-helical protein
ISU61_05750	COG4953	penicillin-binding protein 1C
ISU61_05755	COG3423	Transcriptional regulator
ISU61_05805	COG3328	transposase activity
ISU61_05820	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU61_05830	COG0656	L-ascorbic acid biosynthetic process
ISU61_05835	COG0667	Aldo Keto reductase
ISU61_05865	COG3130	regulation of translation
ISU61_05870	COG3009	Protein conserved in bacteria
ISU61_05875	COG3008	intermembrane lipid transfer
ISU61_05875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU61_05880	COG2995	paraquat-inducible protein a
ISU61_05885	COG0488	(ABC) transporter
ISU61_05895	COG0633	Ferredoxin
ISU61_05895	COG3217	Mosc domain protein beta barrel domain protein
ISU61_05910	COG0308	aminopeptidase N
ISU61_05930	COG1448	Aminotransferase
ISU61_05940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU61_05945	COG3108	Peptidase M15
ISU61_05950	COG2989	Protein conserved in bacteria
ISU61_05975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISU61_05980	COG3173	Aminoglycoside phosphotransferase
ISU61_05995	COG1278	Cold shock
ISU61_06000	COG5383	Protein conserved in bacteria
ISU61_06015	COG2333	competence protein COMEC
ISU61_06015	COG0658	competence protein
ISU61_06025	COG0539	negative regulation of cytoplasmic translation
ISU61_06050	COG5295	Hep Hag repeat protein
ISU61_06050	COG5295	Hep Hag repeat protein
ISU61_06055	COG0252	asparaginase activity
ISU61_06060	COG1944	ATP diphosphatase activity
ISU61_06065	COG2116	formate transmembrane transporter activity
ISU61_06070	COG1882	Formate acetyltransferase
ISU61_06080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISU61_06095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ISU61_06105	COG3107	peptidoglycan biosynthetic process
ISU61_06105	COG1674	ftsk spoiiie
ISU61_06115	COG0492	ferredoxin-NADP+ reductase activity
ISU61_06125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ISU61_06135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ISU61_06145	COG0542	response to heat
ISU61_06155	COG1278	Cold shock
ISU61_06165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU61_06170	COG2990	Protein conserved in bacteria
ISU61_06175	COG3593	DNA synthesis involved in DNA repair
ISU61_06180	COG2431	L-lysine efflux transmembrane transporter activity
ISU61_06190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU61_06195	COG0028	Belongs to the TPP enzyme family
ISU61_06205	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ISU61_06210	COG0702	epimerase
ISU61_06215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU61_06225	COG1605	Chorismate mutase
ISU61_06230	COG1126	abc transporter atp-binding protein
ISU61_06235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU61_06240	COG4215	(ABC) transporter
ISU61_06245	COG4160	amino acid transport
ISU61_06270	COG1120	ATPase activity
ISU61_06275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU61_06280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU61_06305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU61_06320	COG1177	transmembrane transport
ISU61_06325	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU61_06330	COG3842	ATPase activity
ISU61_06335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISU61_06365	COG0671	phosphoesterase, PA-phosphatase related
ISU61_06375	COG1349	DNA-binding transcription factor activity
ISU61_06380	COG0814	amino acid
ISU61_06385	COG1686	Belongs to the peptidase S11 family
ISU61_06390	COG2011	ABC-type metal ion transport system permease component
ISU61_06415	COG0625	glutathione transferase activity
ISU61_06420	COG4771	TonB-dependent receptor
ISU61_06430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU61_06440	COG0833	amino acid
ISU61_06445	COG0583	DNA-binding transcription factor activity
ISU61_06450	COG2855	membrane
ISU61_06475	COG3188	usher protein
ISU61_06480	COG3121	Chaperone
ISU61_06495	COG3710	Transcriptional regulator
ISU61_06500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU61_06500	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ISU61_06500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU61_06505	COG1105	Belongs to the carbohydrate kinase PfkB family
ISU61_06515	COG0494	nUDIX hydrolase
ISU61_06525	COG1129	ABC transporter
ISU61_06560	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_06585	COG0246	Mannitol dehydrogenase
ISU61_06590	COG2186	Transcriptional regulator
ISU61_06595	COG0523	cobalamin synthesis protein
ISU61_06600	COG0671	phosphoesterase, PA-phosphatase related
ISU61_06605	COG0791	NLP P60 protein
ISU61_06610	COG2200	EAL domain
ISU61_06615	COG4166	transmembrane transport
ISU61_06620	COG4174	ABC transporter (Permease)
ISU61_06625	COG4239	(ABC) transporter, permease
ISU61_06630	COG4172	Belongs to the ABC transporter superfamily
ISU61_06640	COG2814	Major facilitator Superfamily
ISU61_06645	COG1187	pseudouridine synthase activity
ISU61_06650	COG1061	Type III restriction enzyme res subunit
ISU61_06675	COG3070	regulator of competence-specific genes
ISU61_06680	COG1289	transmembrane transporter activity
ISU61_06685	COG3304	Inner membrane component domain
ISU61_06690	COG0210	DNA helicase
ISU61_06705	COG1832	CoA-binding protein
ISU61_06725	COG2920	part of a sulfur-relay system
ISU61_06750	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_06760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ISU61_06765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU61_06770	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_06775	COG3425	synthase
ISU61_06785	COG1024	Enoyl-CoA hydratase
ISU61_06790	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_06800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ISU61_06805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISU61_06935	COG0488	(ABC) transporter
ISU61_06945	COG3328	transposase activity
ISU61_06955	COG0303	'Molybdopterin
ISU61_06965	COG1136	(ABC) transporter
ISU61_06995	COG0583	DNA-binding transcription factor activity
ISU61_07000	COG0477	Major facilitator Superfamily
ISU61_07010	COG2311	Membrane
ISU61_07025	COG4211	Belongs to the binding-protein-dependent transport system permease family
ISU61_07030	COG2949	membrane
ISU61_07045	COG1346	cytolysis
ISU61_07055	COG2814	Major facilitator Superfamily
ISU61_07085	COG0489	protein tyrosine kinase activity
ISU61_07100	COG2982	Protein involved in outer membrane biogenesis
ISU61_07105	COG1253	flavin adenine dinucleotide binding
ISU61_07110	COG4114	ferric iron reductase
ISU61_07115	COG0076	glutamate decarboxylase activity
ISU61_07120	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ISU61_07135	COG1120	ATPase activity
ISU61_07140	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU61_07145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU61_07150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU61_07165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU61_07170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU61_07180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ISU61_07180	COG0140	phosphoribosyl-ATP diphosphatase activity
ISU61_07200	COG0131	Imidazoleglycerol-phosphate dehydratase
ISU61_07200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU61_07210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ISU61_07225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU61_07245	COG1129	ABC transporter
ISU61_07250	COG1129	ABC transporter
ISU61_07255	COG0371	Dehydrogenase
ISU61_07260	COG0531	amino acid
ISU61_07270	COG2925	Exonuclease
ISU61_07295	COG2271	Major facilitator Superfamily
ISU61_07300	COG3011	Protein conserved in bacteria
ISU61_07305	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_07315	COG4948	Mandelate Racemase Muconate Lactonizing
ISU61_07330	COG0534	Mate efflux family protein
ISU61_07350	COG3122	Protein conserved in bacteria
ISU61_07375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ISU61_07395	COG2223	nitrite transmembrane transporter activity
ISU61_07425	COG1132	(ABC) transporter
ISU61_07435	COG2207	Transcriptional regulator
ISU61_07470	COG1113	amino acid transport
ISU61_07490	COG1496	oxidoreductase activity
ISU61_07495	COG2226	methyltransferase
ISU61_07505	COG5001	Diguanylate cyclase
ISU61_07505	COG5002	protein histidine kinase activity
ISU61_07505	COG3447	MASE1 domain protein
ISU61_07525	COG3657	addiction module killer protein
ISU61_07575	COG0582	viral genome integration into host DNA
ISU61_07595	COG2867	negative regulation of translational initiation
ISU61_07605	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU61_07610	COG0497	DNA recombination
ISU61_07615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ISU61_07630	COG2009	succinate dehydrogenase
ISU61_07635	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ISU61_07640	COG1053	succinate dehydrogenase
ISU61_07650	COG0567	Dehydrogenase, E1 component
ISU61_07655	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU61_07665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ISU61_07670	COG1271	oxidase subunit
ISU61_07675	COG1294	oxidase, subunit
ISU61_07680	COG4890	Cyd operon protein YbgT
ISU61_07685	COG3790	cyd operon protein YbgE
ISU61_07690	COG0824	Thioesterase
ISU61_07695	COG0811	peptide transport
ISU61_07700	COG0848	biopolymer transport protein
ISU61_07705	COG3064	Membrane
ISU61_07705	COG3064	Membrane
ISU61_07715	COG2885	chlorophyll binding
ISU61_07720	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ISU61_07755	COG1230	cation diffusion facilitator family transporter
ISU61_07760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU61_07775	COG2017	converts alpha-aldose to the beta-anomer
ISU61_07790	COG1085	galactose-1-phosphate uridylyltransferase
ISU61_07795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ISU61_07805	COG1119	ATPase activity
ISU61_07810	COG3585	molybdate ion transport
ISU61_07810	COG2005	Transcriptional regulator
ISU61_07820	COG0725	ABC transporter, periplasmic molybdate-binding protein
ISU61_07825	COG4149	molybdate abc transporter
ISU61_07835	COG0561	phosphatase activity
ISU61_07860	COG2226	methyltransferase
ISU61_07870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ISU61_07880	COG4628	conserved protein (DUF2132)
ISU61_07905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ISU61_07915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ISU61_07920	COG0314	molybdopterin synthase activity
ISU61_07925	COG0670	Belongs to the BI1 family
ISU61_07950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU61_07955	COG0583	DNA-binding transcription factor activity
ISU61_07965	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ISU61_08000	COG1902	pentaerythritol trinitrate reductase activity
ISU61_08020	COG0842	Transport permease protein
ISU61_08025	COG0842	Transport permease protein
ISU61_08030	COG1131	(ABC) transporter
ISU61_08040	COG1309	transcriptional regulator
ISU61_08045	COG0513	Belongs to the DEAD box helicase family
ISU61_08080	COG3328	transposase activity
ISU61_08105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU61_08115	COG1686	Belongs to the peptidase S11 family
ISU61_08120	COG0277	FAD linked oxidase domain protein
ISU61_08140	COG2261	transglycosylase associated protein
ISU61_08150	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ISU61_08165	COG4807	Protein conserved in bacteria
ISU61_08185	COG1122	ATPase activity
ISU61_08205	COG2897	thiosulfate sulfurtransferase activity
ISU61_08210	COG1732	Glycine betaine
ISU61_08215	COG1732	Glycine betaine
ISU61_08220	COG1174	glycine betaine transport
ISU61_08225	COG1125	glycine betaine transport
ISU61_08230	COG1174	glycine betaine transport
ISU61_08235	COG0531	amino acid
ISU61_08240	COG1982	Orn Lys Arg decarboxylase major
ISU61_08250	COG0697	spore germination
ISU61_08275	COG0814	amino acid
ISU61_08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU61_08315	COG2205	protein histidine kinase activity
ISU61_08315	COG0784	Response regulator, receiver
ISU61_08325	COG2198	Histidine kinase
ISU61_08325	COG0642	Histidine kinase
ISU61_08330	COG2198	Histidine kinase
ISU61_08330	COG0642	Histidine kinase
ISU61_08335	COG2223	nitrite transmembrane transporter activity
ISU61_08355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISU61_08395	COG3395	kinase activity
ISU61_08405	COG1349	DNA-binding transcription factor activity
ISU61_08410	COG3622	Belongs to the hyi family
ISU61_08430	COG4386	tail sheath protein
ISU61_08470	COG3299	homolog of phage Mu protein gp47
ISU61_08490	COG1737	Transcriptional regulator
ISU61_08495	COG2723	6-phospho-beta-galactosidase activity
ISU61_08500	COG3328	transposase activity
ISU61_08520	COG3157	Type VI secretion system effector, Hcp
ISU61_08535	COG3083	sulfuric ester hydrolase activity
ISU61_08540	COG3082	Protein of unknown function (DUF1414)
ISU61_08560	COG1067	ATP-dependent peptidase activity
ISU61_08620	COG4771	TonB-dependent receptor
ISU61_08625	COG1021	2,3-dihydroxybenzoate-AMP ligase
ISU61_08645	COG2226	methyltransferase
ISU61_08645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU61_08645	COG3433	isochorismatase activity
ISU61_08660	COG1132	(ABC) transporter
ISU61_08665	COG2814	Major facilitator Superfamily
ISU61_08670	COG1169	isochorismate synthase
ISU61_08675	COG0582	viral genome integration into host DNA
ISU61_08685	COG3121	Chaperone
ISU61_08695	COG3188	usher protein
ISU61_08730	COG2030	dehydratase
ISU61_08755	COG2814	Major facilitator Superfamily
ISU61_08770	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU61_08775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU61_08785	COG1349	DNA-binding transcription factor activity
ISU61_08795	COG2066	Belongs to the glutaminase family
ISU61_08810	COG0672	)-iron permease
ISU61_08825	COG0577	efflux transmembrane transporter activity
ISU61_08825	COG1136	(ABC) transporter
ISU61_08835	COG0577	efflux transmembrane transporter activity
ISU61_08835	COG1136	(ABC) transporter
ISU61_08855	COG0006	proline dipeptidase activity
ISU61_08865	COG1649	PFAM Uncharacterised BCR, COG1649
ISU61_08865	COG0726	polysaccharide deacetylase
ISU61_08870	COG1215	transferase activity, transferring glycosyl groups
ISU61_08875	COG3658	cytochrome
ISU61_08895	COG0387	Pfam Sodium calcium exchanger
ISU61_08900	COG3850	Histidine kinase
ISU61_08910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU61_08990	COG3121	Chaperone
ISU61_09010	COG3008	intermembrane lipid transfer
ISU61_09015	COG2995	paraquat-inducible protein a
ISU61_09020	COG1956	GAF domain-containing protein
ISU61_09030	COG0793	Belongs to the peptidase S41A family
ISU61_09040	COG3539	Fimbrial protein
ISU61_09045	COG3121	Chaperone
ISU61_09060	COG3121	Chaperone
ISU61_09065	COG2814	Major facilitator Superfamily
ISU61_09070	COG0823	Involved in the tonB-independent uptake of proteins
ISU61_09080	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU61_09085	COG1823	symporter activity
ISU61_09090	COG1988	membrane-bound metal-dependent
ISU61_09095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU61_09100	COG1653	transport
ISU61_09105	COG3842	ATPase activity
ISU61_09110	COG0395	ABC-type sugar transport system, permease component
ISU61_09115	COG1175	transmembrane transport
ISU61_09125	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_09135	COG1917	Cupin 2, conserved barrel domain protein
ISU61_09140	COG3328	transposase activity
ISU61_09150	COG2824	Alkylphosphonate utilization operon protein PhnA
ISU61_09160	COG1704	LemA family
ISU61_09180	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU61_09185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU61_09190	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU61_09200	COG1138	Cytochrome C-type biogenesis protein
ISU61_09205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISU61_09210	COG3088	subunit of a heme lyase
ISU61_09210	COG4235	cytochrome complex assembly
ISU61_09215	COG4235	cytochrome complex assembly
ISU61_09215	COG3088	subunit of a heme lyase
ISU61_09230	COG3691	Protein conserved in bacteria
ISU61_09245	COG2062	phosphohistidine phosphatase, SixA
ISU61_09255	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU61_09270	COG0730	response to heat
ISU61_09275	COG3101	peptidyl-lysine hydroxylation
ISU61_09290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU61_09295	COG1794	racemase activity, acting on amino acids and derivatives
ISU61_09310	COG0697	spore germination
ISU61_09325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU61_09335	COG0586	Pfam SNARE associated Golgi protein
ISU61_09345	COG0285	dihydrofolate synthase activity
ISU61_09350	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ISU61_09355	COG1286	toxin biosynthetic process
ISU61_09360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ISU61_09370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU61_09375	COG4215	(ABC) transporter
ISU61_09380	COG4160	amino acid transport
ISU61_09385	COG4598	ABC transporter
ISU61_09390	COG1090	epimerase
ISU61_09400	COG0622	Phosphoesterase
ISU61_09405	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ISU61_09415	COG3328	transposase activity
ISU61_09435	COG1609	Transcriptional regulator
ISU61_09440	COG0280	phosphate acetyltransferase
ISU61_09440	COG0857	belongs to the CobB CobQ family
ISU61_09460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU61_09465	COG0471	metal ion transport
ISU61_09465	COG0490	domain, Protein
ISU61_09480	COG0436	Aminotransferase
ISU61_09485	COG0583	DNA-binding transcription factor activity
ISU61_09495	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU61_09515	COG1034	ATP synthesis coupled electron transport
ISU61_09530	COG0839	Belongs to the complex I subunit 6 family
ISU61_09540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ISU61_09545	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU61_09560	COG2731	YhcH YjgK YiaL family protein
ISU61_09565	COG3265	gluconokinase activity
ISU61_09570	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_09575	COG1649	PFAM Uncharacterised BCR, COG1649
ISU61_09580	COG1609	Transcriptional regulator
ISU61_09585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU61_09600	COG0129	dihydroxy-acid dehydratase activity
ISU61_09605	COG4575	ribosome binding
ISU61_09615	COG1169	isochorismate synthase
ISU61_09630	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ISU61_09645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISU61_09670	COG1126	abc transporter atp-binding protein
ISU61_09675	COG0765	amino acid transport
ISU61_09680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU61_09710	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ISU61_09730	COG1063	alcohol dehydrogenase
ISU61_09735	COG1879	ABC-type sugar transport system periplasmic component
ISU61_09740	COG1129	ABC transporter
ISU61_09745	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_09750	COG1609	Transcriptional regulator
ISU61_09755	COG0583	DNA-binding transcription factor activity
ISU61_09760	COG0473	3-isopropylmalate dehydrogenase activity
ISU61_09770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU61_09775	COG4638	Rieske (2fe-2S)
ISU61_09780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU61_09785	COG2831	hemolysin activation secretion protein
ISU61_09790	COG3210	domain, Protein
ISU61_09810	COG3210	domain, Protein
ISU61_09820	COG3842	ATPase activity
ISU61_09835	COG1609	Transcriptional regulator
ISU61_09850	COG0395	ABC-type sugar transport system, permease component
ISU61_09855	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ISU61_09880	COG0668	transmembrane transport
ISU61_09885	COG1518	maintenance of DNA repeat elements
ISU61_09890	COG1203	CRISPR-associated helicase, Cas3
ISU61_09915	COG0667	Aldo Keto reductase
ISU61_09925	COG0477	Major facilitator Superfamily
ISU61_09955	COG2771	luxR family
ISU61_09960	COG3916	Acyl-homoserine-lactone synthase
ISU61_09980	COG0628	permease
ISU61_10000	COG3328	transposase activity
ISU61_10020	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ISU61_10030	COG1530	ribonuclease E activity
ISU61_10035	COG0564	pseudouridine synthase activity
ISU61_10040	COG0424	maF-like protein
ISU61_10045	COG1399	metal-binding, possibly nucleic acid-binding protein
ISU61_10050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ISU61_10080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU61_10090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU61_10095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ISU61_10105	COG0470	DNA polymerase III
ISU61_10110	COG0084	hydrolase, TatD family'
ISU61_10115	COG1263	PTS System
ISU61_10115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU61_10125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISU61_10130	COG0537	adenosine 5'-monophosphoramidase activity
ISU61_10135	COG5633	Lipoprotein
ISU61_10150	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU61_10160	COG1252	NADH dehydrogenase
ISU61_10175	COG3328	transposase activity
ISU61_10180	COG3134	Outer membrane lipoprotein
ISU61_10185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ISU61_10190	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU61_10200	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU61_10205	COG1940	carbohydrate kinase activity
ISU61_10230	COG2850	peptidyl-arginine hydroxylation
ISU61_10240	COG0745	RESPONSE REGULATOR receiver
ISU61_10250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISU61_10270	COG1187	pseudouridine synthase activity
ISU61_10275	COG0538	isocitrate dehydrogenase activity
ISU61_10290	COG0840	transmembrane signaling receptor activity
ISU61_10295	COG0702	epimerase
ISU61_10300	COG1733	regulation of RNA biosynthetic process
ISU61_10325	COG1522	sequence-specific DNA binding
ISU61_10335	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_10335	COG0604	alcohol dehydrogenase
ISU61_10335	COG3321	synthase
ISU61_10360	COG1285	pathogenesis
ISU61_10385	COG1360	Flagellar Motor Protein
ISU61_10390	COG0643	Histidine kinase
ISU61_10390	COG2198	Histidine kinase
ISU61_10395	COG0835	chemotaxis
ISU61_10400	COG2271	Major facilitator Superfamily
ISU61_10405	COG0251	oxidation-reduction process
ISU61_10415	COG2964	Protein conserved in bacteria
ISU61_10435	COG0840	transmembrane signaling receptor activity
ISU61_10440	COG0840	transmembrane signaling receptor activity
ISU61_10445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ISU61_10455	COG0745	RESPONSE REGULATOR receiver
ISU61_10460	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ISU61_10465	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU61_10475	COG5295	Hep Hag repeat protein
ISU61_10485	COG3328	transposase activity
ISU61_10490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ISU61_10530	COG0402	S-adenosylhomocysteine deaminase activity
ISU61_10545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU61_10550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU61_10555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU61_10595	COG3328	transposase activity
ISU61_10615	COG0500	methyltransferase
ISU61_10660	COG5002	protein histidine kinase activity
ISU61_10710	COG0012	GTP binding
ISU61_10725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ISU61_10750	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU61_10770	COG0659	secondary active sulfate transmembrane transporter activity
ISU61_10790	COG3833	ABC-type maltose transport systems, permease component
ISU61_10795	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU61_10815	COG0584	glycerophosphoryl diester phosphodiesterase
ISU61_10820	COG1940	carbohydrate kinase activity
ISU61_10835	COG3381	protein complex oligomerization
ISU61_10850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU61_10860	COG0728	peptidoglycan biosynthetic process
ISU61_10880	COG3102	Protein conserved in bacteria
ISU61_10900	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ISU61_10905	COG1801	Protein of unknown function DUF72
ISU61_10910	COG3328	transposase activity
ISU61_10920	COG0494	nUDIX hydrolase
ISU61_10945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU61_10955	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ISU61_10960	COG0739	heme binding
ISU61_10965	COG1560	Kdo2-lipid A biosynthetic process
ISU61_10975	COG0469	pyruvate kinase activity
ISU61_10980	COG1737	Transcriptional regulator
ISU61_10985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ISU61_10990	COG0800	Aldolase
ISU61_11005	COG0251	oxidation-reduction process
ISU61_11010	COG1199	ATP-dependent helicase activity
ISU61_11020	COG3065	identical protein binding
ISU61_11030	COG0318	PFAM AMP-dependent synthetase and ligase
ISU61_11035	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ISU61_11040	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ISU61_11045	COG2894	cell division
ISU61_11060	COG2951	lytic endotransglycosylase activity
ISU61_11065	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISU61_11075	COG0582	viral genome integration into host DNA
ISU61_11135	COG3328	transposase activity
ISU61_11145	COG1104	cysteine desulfurase activity
ISU61_11175	COG2719	SpoVR family
ISU61_11185	COG2814	Major facilitator Superfamily
ISU61_11195	COG0583	DNA-binding transcription factor activity
ISU61_11210	COG2766	serine protein kinase
ISU61_11215	COG3713	MltA-interacting MipA family protein
ISU61_11235	COG3139	Protein of unknown function (DUF1315)
ISU61_11240	COG1335	isochorismatase
ISU61_11245	COG0252	asparaginase activity
ISU61_11250	COG0616	signal peptide processing
ISU61_11255	COG0778	Nitroreductase
ISU61_11260	COG0709	Synthesizes selenophosphate from selenide and ATP
ISU61_11265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ISU61_11275	COG0494	nUDIX hydrolase
ISU61_11280	COG0708	Exodeoxyribonuclease III
ISU61_11285	COG0583	DNA-binding transcription factor activity
ISU61_11305	COG0788	formyltetrahydrofolate deformylase activity
ISU61_11315	COG0745	RESPONSE REGULATOR receiver
ISU61_11335	COG1012	belongs to the aldehyde dehydrogenase family
ISU61_11335	COG1454	alcohol dehydrogenase
ISU61_11340	COG2095	MarC family integral membrane protein
ISU61_11350	COG0601	transmembrane transport
ISU61_11355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU61_11360	COG0444	Belongs to the ABC transporter superfamily
ISU61_11365	COG4608	Belongs to the ABC transporter superfamily
ISU61_11410	COG2350	Protein conserved in bacteria
ISU61_11415	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ISU61_11420	COG3328	transposase activity
ISU61_11455	COG3047	cAMP biosynthetic process
ISU61_11475	COG0135	phosphoribosylanthranilate isomerase activity
ISU61_11475	COG0134	indole-3-glycerol-phosphate synthase activity
ISU61_11485	COG0512	Glutamine amidotransferase of anthranilate synthase
ISU61_11505	COG0009	L-threonylcarbamoyladenylate synthase
ISU61_11510	COG1187	pseudouridine synthase activity
ISU61_11520	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_11525	COG0616	signal peptide processing
ISU61_11545	COG0583	DNA-binding transcription factor activity
ISU61_11555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISU61_11565	COG0671	phosphoesterase, PA-phosphatase related
ISU61_11570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ISU61_11575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ISU61_11590	COG0023	Translation Initiation Factor
ISU61_11610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISU61_11615	COG2879	small protein
ISU61_11620	COG1966	Carbon starvation protein
ISU61_11650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU61_11655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ISU61_11665	COG4659	FMN binding
ISU61_11670	COG4658	electron transport chain
ISU61_11675	COG2207	Transcriptional regulator
ISU61_11675	COG3708	Transcriptional regulator
ISU61_11705	COG1132	(ABC) transporter
ISU61_11715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU61_11720	COG2274	protein secretion by the type I secretion system
ISU61_11735	COG1879	ABC-type sugar transport system periplasmic component
ISU61_11740	COG1129	ABC transporter
ISU61_11745	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_11755	COG0673	inositol 2-dehydrogenase activity
ISU61_11760	COG0385	Bile acid
ISU61_11770	COG5339	Protein conserved in bacteria
ISU61_11780	COG0114	fumarate hydratase activity
ISU61_11790	COG2814	Major facilitator Superfamily
ISU61_11795	COG0583	DNA-binding transcription factor activity
ISU61_11800	COG1940	carbohydrate kinase activity
ISU61_11805	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ISU61_11810	COG0038	chloride channel
ISU61_11815	COG1609	Transcriptional regulator
ISU61_11835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU61_11845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ISU61_11875	COG0028	Belongs to the TPP enzyme family
ISU61_11880	COG0440	acetolactate synthase activity
ISU61_11885	COG1011	Hydrolase
ISU61_11905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU61_11910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISU61_11915	COG0589	response to stress
ISU61_11920	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ISU61_11925	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ISU61_11935	COG0531	amino acid
ISU61_11945	COG0745	RESPONSE REGULATOR receiver
ISU61_11950	COG2205	protein histidine kinase activity
ISU61_11955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ISU61_11980	COG3038	cytochrome b561
ISU61_11990	COG3591	Belongs to the peptidase S1B family
ISU61_12005	COG1643	Atp-dependent helicase
ISU61_12015	COG2390	Transcriptional regulator
ISU61_12020	COG0246	Mannitol dehydrogenase
ISU61_12025	COG3784	Protein of unknown function (DUF1318)
ISU61_12035	COG2911	Protein conserved in bacteria
ISU61_12040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU61_12045	COG3187	Heat shock protein
ISU61_12050	COG3042	response to heat
ISU61_12055	COG1285	pathogenesis
ISU61_12065	COG1013	pyruvate-flavodoxin oxidoreductase activity
ISU61_12065	COG0674	pyruvate-flavodoxin oxidoreductase activity
ISU61_12065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ISU61_12065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU61_12075	COG0657	acetylesterase activity
ISU61_12090	COG4166	transmembrane transport
ISU61_12095	COG2866	Carboxypeptidase
ISU61_12100	COG4948	Mandelate Racemase Muconate Lactonizing
ISU61_12105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ISU61_12115	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISU61_12120	COG1842	Phage shock protein A
ISU61_12130	COG1983	PspC domain protein
ISU61_12140	COG3106	COG3106 Predicted ATPase
ISU61_12150	COG5654	RES domain protein
ISU61_12155	COG5642	Protein of unknown function (DUF2384)
ISU61_12170	COG4166	transmembrane transport
ISU61_12175	COG4168	peptide transport system, permease
ISU61_12180	COG4171	peptide transport system, permease
ISU61_12190	COG4172	Belongs to the ABC transporter superfamily
ISU61_12195	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU61_12195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU61_12200	COG3104	oligopeptide transport
ISU61_12215	COG0625	glutathione transferase activity
ISU61_12235	COG3895	Periplasmic Protein
ISU61_12245	COG3133	Outer membrane lipoprotein
ISU61_12255	COG4989	oxidoreductase activity
ISU61_12260	COG3313	Fe-S protein
ISU61_12265	COG2194	sulfuric ester hydrolase activity
ISU61_12270	COG1309	transcriptional regulator
ISU61_12275	COG1902	pentaerythritol trinitrate reductase activity
ISU61_12285	COG0346	lactoylglutathione lyase activity
ISU61_12290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISU61_12300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ISU61_12305	COG0791	NLP P60 protein
ISU61_12325	COG0583	DNA-binding transcription factor activity
ISU61_12330	COG2814	Major facilitator Superfamily
ISU61_12335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ISU61_12340	COG0307	riboflavin synthase, alpha
ISU61_12390	COG1388	LysM domain
ISU61_12390	COG1376	ErfK ybiS ycfS ynhG family protein
ISU61_12405	COG0719	Fe-S assembly protein
ISU61_12410	COG0396	ATPase activity
ISU61_12415	COG0719	Fe-S assembly protein
ISU61_12420	COG0316	Belongs to the HesB IscA family
ISU61_12425	COG2050	protein possibly involved in aromatic compounds catabolism
ISU61_12430	COG0247	lactate metabolic process
ISU61_12430	COG0277	FAD linked oxidase domain protein
ISU61_12435	COG0628	permease
ISU61_12445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU61_12445	COG0574	Belongs to the PEP-utilizing enzyme family
ISU61_12470	COG0791	NLP P60 protein
ISU61_12520	COG0386	Belongs to the glutathione peroxidase family
ISU61_12535	COG0776	regulation of translation
ISU61_12540	COG0072	phenylalanine-tRNA ligase activity
ISU61_12540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ISU61_12575	COG4249	Peptidase C14 caspase catalytic subunit p20
ISU61_12595	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISU61_12600	COG1121	(ABC) transporter
ISU61_12605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU61_12610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU61_12620	COG3001	Fructosamine kinase
ISU61_12630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU61_12635	COG3328	transposase activity
ISU61_12680	COG0516	GMP reductase activity
ISU61_12680	COG0517	IMP dehydrogenase activity
ISU61_12690	COG1645	bacterial-type flagellum-dependent swarming motility
ISU61_12705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU61_12710	COG2976	Protein conserved in bacteria
ISU61_12750	COG3468	outer membrane autotransporter barrel domain protein
ISU61_12755	COG3468	outer membrane autotransporter barrel domain protein
ISU61_12780	COG2975	iron-sulfur cluster assembly
ISU61_12785	COG0633	Ferredoxin
ISU61_12790	COG0443	Heat shock 70 kDa protein
ISU61_12805	COG0822	iron-sulfur transferase activity
ISU61_12810	COG1104	cysteine desulfurase activity
ISU61_12830	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU61_12835	COG3683	transport system, periplasmic component
ISU61_12840	COG3711	transcriptional antiterminator
ISU61_12845	COG2814	Major facilitator Superfamily
ISU61_12865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU61_12865	COG1017	nitric oxide dioxygenase activity
ISU61_12870	COG2188	Transcriptional regulator
ISU61_12875	COG0347	Belongs to the P(II) protein family
ISU61_12880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ISU61_12880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU61_12885	COG2204	response regulator
ISU61_12890	COG3170	Tfp pilus assembly protein FimV
ISU61_12895	COG2205	protein histidine kinase activity
ISU61_12940	COG0560	Phosphoserine phosphatase
ISU61_12950	COG1737	Transcriptional regulator
ISU61_12970	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU61_12985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ISU61_13020	COG3086	response to oxidative stress
ISU61_13025	COG3026	antisigma factor binding
ISU61_13040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ISU61_13050	COG0513	Belongs to the DEAD box helicase family
ISU61_13095	COG1984	allophanate hydrolase subunit 2
ISU61_13110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ISU61_13115	COG5212	phosphodiesterase
ISU61_13125	COG3272	Protein of unknown function (DUF1722)
ISU61_13160	COG2205	protein histidine kinase activity
ISU61_13165	COG0745	RESPONSE REGULATOR receiver
ISU61_13180	COG0033	Phosphoglucomutase
ISU61_13185	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ISU61_13200	COG1917	Cupin 2, conserved barrel domain protein
ISU61_13200	COG2169	Transcriptional regulator
ISU61_13205	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISU61_13210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU61_13215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU61_13225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU61_13235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU61_13245	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU61_13250	COG4413	Urea transporter
ISU61_13260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ISU61_13285	COG0831	urea catabolic process
ISU61_13290	COG1124	(ABC) transporter
ISU61_13295	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ISU61_13300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU61_13310	COG0747	negative chemotaxis
ISU61_13315	COG1278	Cold shock
ISU61_13330	COG3328	transposase activity
ISU61_13335	COG3188	usher protein
ISU61_13340	COG3121	Chaperone
ISU61_13400	COG2951	lytic endotransglycosylase activity
ISU61_13435	COG0243	molybdopterin cofactor binding
ISU61_13440	COG0437	4 iron, 4 sulfur cluster binding
ISU61_13445	COG3302	dmso reductase anchor subunit
ISU61_13450	COG3381	protein complex oligomerization
ISU61_13480	COG3038	cytochrome b561
ISU61_13510	COG0667	Aldo Keto reductase
ISU61_13525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU61_13580	COG3530	Putative quorum-sensing-regulated virulence factor
ISU61_13595	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ISU61_13605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU61_13625	COG2205	protein histidine kinase activity
ISU61_13630	COG0745	RESPONSE REGULATOR receiver
ISU61_13635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU61_13650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ISU61_13670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISU61_13680	COG3850	Histidine kinase
ISU61_13680	COG5002	protein histidine kinase activity
ISU61_13685	COG0745	RESPONSE REGULATOR receiver
ISU61_13700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ISU61_13705	COG4208	sulfate ABC transporter
ISU61_13710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ISU61_13715	COG4150	thiosulfate binding
ISU61_13725	COG1737	Transcriptional regulator
ISU61_13730	COG2731	YhcH YjgK YiaL family protein
ISU61_13740	COG4886	Leucine-rich repeat (LRR) protein
ISU61_13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISU61_13755	COG2837	iron assimilation
ISU61_13765	COG3111	PFAM Bacterial OB fold (BOF) protein
ISU61_13805	COG3005	denitrification pathway
ISU61_13810	COG3043	anaerobic respiration
ISU61_13820	COG3062	negative regulation of establishment of protein localization
ISU61_13825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU61_13825	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU61_13830	COG2197	response regulator
ISU61_13840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU61_13850	COG1988	membrane-bound metal-dependent
ISU61_13855	COG0641	radical SAM
ISU61_13860	COG3119	arylsulfatase activity
ISU61_13870	COG3842	ATPase activity
ISU61_13875	COG1175	transmembrane transport
ISU61_13890	COG1393	Belongs to the ArsC family
ISU61_13900	COG1876	peptidase activity
ISU61_13920	COG2321	neutral zinc metallopeptidase
ISU61_13935	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ISU61_13945	COG2716	regulation of RNA biosynthetic process
ISU61_13950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ISU61_13960	COG0628	permease
ISU61_13965	COG4783	chaperone-mediated protein folding
ISU61_13970	COG1393	Belongs to the ArsC family
ISU61_13995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ISU61_14000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU61_14015	COG0581	inorganic phosphate transmembrane transporter activity
ISU61_14025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ISU61_14040	COG2239	Acts as a magnesium transporter
ISU61_14045	COG0443	Heat shock 70 kDa protein
ISU61_14050	COG1177	transmembrane transport
ISU61_14055	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU61_14065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISU61_14075	COG3842	ATPase activity
ISU61_14100	COG2205	protein histidine kinase activity
ISU61_14105	COG0745	RESPONSE REGULATOR receiver
ISU61_14110	COG3422	double-strand break repair
ISU61_14115	COG0826	peptidase U32
ISU61_14135	COG0351	phosphomethylpyrimidine kinase
ISU61_14150	COG3328	transposase activity
ISU61_14235	COG3188	usher protein
ISU61_14240	COG3328	transposase activity
ISU61_14275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ISU61_14280	COG4175	Glycine betaine
ISU61_14285	COG4176	ABC-type proline glycine betaine transport system permease component
ISU61_14290	COG2113	Glycine betaine
ISU61_14320	COG1953	Uracil, thiamine, allantoin
ISU61_14340	COG2226	methyltransferase
ISU61_14345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU61_14350	COG1388	LysM domain
ISU61_14350	COG0741	lytic transglycosylase activity
ISU61_14365	COG0656	L-ascorbic acid biosynthetic process
ISU61_14400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU61_14410	COG2011	ABC-type metal ion transport system permease component
ISU61_14415	COG1464	Belongs to the NlpA lipoprotein family
ISU61_14425	COG1720	tRNA m6t6A37 methyltransferase activity
ISU61_14435	COG3015	lipoprotein NlpE involved in copper resistance
ISU61_14445	COG4681	YaeQ
ISU61_14455	COG4568	rho-dependent transcription termination
ISU61_14465	COG0037	tRNA processing
ISU61_14470	COG0346	lactoylglutathione lyase activity
ISU61_14480	COG0587	DNA-directed DNA polymerase activity
ISU61_14505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ISU61_14520	COG0750	zinc metalloprotease
ISU61_14525	COG0575	Belongs to the CDS family
ISU61_14585	COG0564	pseudouridine synthase activity
ISU61_14590	COG3098	single-species biofilm formation
ISU61_14610	COG1611	Belongs to the LOG family
ISU61_14625	COG2363	Small membrane protein
ISU61_14630	COG0583	DNA-binding transcription factor activity
ISU61_14640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISU61_14645	COG2166	iron-sulfur cluster assembly
ISU61_14650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ISU61_14655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ISU61_14670	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU61_14680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ISU61_14685	COG1074	ATP-dependent DNA helicase activity
ISU61_14695	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ISU61_14790	COG1609	Transcriptional regulator
ISU61_14800	COG0583	DNA-binding transcription factor activity
ISU61_14805	COG2814	Major facilitator Superfamily
ISU61_14810	COG0583	DNA-binding transcription factor activity
ISU61_14825	COG0840	transmembrane signaling receptor activity
ISU61_14870	COG2165	general secretion pathway protein
ISU61_14890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU61_14910	COG0288	reversible hydration of carbon dioxide
ISU61_14950	COG2259	Doxx family
ISU61_14960	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ISU61_14965	COG4575	ribosome binding
ISU61_14980	COG0586	Pfam SNARE associated Golgi protein
ISU61_14995	COG2271	Major facilitator Superfamily
ISU61_15010	COG2721	sulfolactate sulfo-lyase activity
ISU61_15030	COG0673	inositol 2-dehydrogenase activity
ISU61_15035	COG1451	nucleotide metabolic process
ISU61_15050	COG1902	pentaerythritol trinitrate reductase activity
ISU61_15050	COG0446	pyridine nucleotide-disulphide oxidoreductase
ISU61_15055	COG3247	response to pH
ISU61_15085	COG4245	von Willebrand factor, type A
ISU61_15090	COG2831	hemolysin activation secretion protein
ISU61_15095	COG3210	domain, Protein
ISU61_15125	COG3210	domain, Protein
ISU61_15130	COG3210	domain, Protein
ISU61_15150	COG3842	ATPase activity
ISU61_15155	COG3459	Glycosyltransferase 36 associated
ISU61_15160	COG1609	Transcriptional regulator
ISU61_15165	COG2182	Extracellular solute-binding protein
ISU61_15175	COG0395	ABC-type sugar transport system, permease component
ISU61_15195	COG1289	transmembrane transporter activity
ISU61_15215	COG0436	Aminotransferase
ISU61_15235	COG0251	oxidation-reduction process
ISU61_15295	COG3328	transposase activity
ISU61_15320	COG0358	DNA primase activity
ISU61_15325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ISU61_15340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISU61_15355	COG4991	sh3 domain protein
ISU61_15360	COG3025	triphosphatase activity
ISU61_15375	COG0531	amino acid
ISU61_15395	COG3384	dioxygenase
ISU61_15400	COG0754	glutathionylspermidine amidase activity
ISU61_15410	COG1538	Outer membrane efflux protein
ISU61_15415	COG0494	nUDIX hydrolase
ISU61_15420	COG3151	Protein conserved in bacteria
ISU61_15425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ISU61_15430	COG3150	esterase
ISU61_15440	COG0583	DNA-binding transcription factor activity
ISU61_15445	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISU61_15455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ISU61_15465	COG2132	Multicopper oxidase
ISU61_15475	COG0656	L-ascorbic acid biosynthetic process
ISU61_15485	COG1979	alcohol dehydrogenase
ISU61_15490	COG2207	Transcriptional regulator
ISU61_15495	COG0586	Pfam SNARE associated Golgi protein
ISU61_15500	COG0626	cystathionine gamma-synthase activity
ISU61_15505	COG0811	peptide transport
ISU61_15510	COG0848	biopolymer transport protein
ISU61_15560	COG4964	Belongs to the GSP D family
ISU61_15565	COG4964	Belongs to the GSP D family
ISU61_15600	COG4592	Periplasmic binding protein
ISU61_15620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU61_15625	COG1684	flagellar biosynthetic protein fliR
ISU61_15630	COG1987	bacterial-type flagellum assembly
ISU61_15655	COG1677	Flagellar hook-basal body complex protein FliE
ISU61_15695	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ISU61_15700	COG1815	bacterial-type flagellum-dependent cell motility
ISU61_15705	COG1558	bacterial-type flagellum-dependent cell motility
ISU61_15710	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ISU61_15715	COG1749	Flagellar hook protein flgE
ISU61_15720	COG4787	bacterial-type flagellum-dependent cell motility
ISU61_15725	COG4786	Flagellar basal body rod
ISU61_15735	COG1706	bacterial-type flagellum-dependent cell motility
ISU61_15745	COG1256	bacterial-type flagellum assembly
ISU61_15765	COG3710	Transcriptional regulator
ISU61_15790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ISU61_15815	COG1191	sigma factor activity
ISU61_15820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ISU61_15915	COG1175	transmembrane transport
ISU61_15920	COG3833	ABC-type maltose transport systems, permease component
ISU61_15935	COG0527	aspartate kinase activity
ISU61_15955	COG1414	Transcriptional regulator
ISU61_15965	COG2224	Isocitrate lyase
ISU61_15970	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ISU61_15980	COG3328	transposase activity
ISU61_16020	COG0151	Belongs to the GarS family
ISU61_16040	COG1515	deoxyribonuclease V activity
ISU61_16075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISU61_16125	COG0250	Participates in transcription elongation, termination and antitermination
ISU61_16175	COG3119	arylsulfatase activity
ISU61_16180	COG1349	DNA-binding transcription factor activity
ISU61_16190	COG2222	sugar isomerase
ISU61_16195	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU61_16200	COG3715	PTS system
ISU61_16205	COG3716	PTS system mannose fructose sorbose family IID component
ISU61_16210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU61_16220	COG1028	Short-chain dehydrogenase reductase Sdr
ISU61_16230	COG0641	radical SAM
ISU61_16235	COG3119	arylsulfatase activity
ISU61_16260	COG2271	Major facilitator Superfamily
ISU61_16280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU61_16280	COG1263	PTS System
ISU61_16285	COG1874	Beta-galactosidase
ISU61_16290	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ISU61_16295	COG3833	ABC-type maltose transport systems, permease component
ISU61_16300	COG1175	transmembrane transport
ISU61_16305	COG2182	Extracellular solute-binding protein
ISU61_16315	COG1129	ABC transporter
ISU61_16320	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_16325	COG1879	ABC-type sugar transport system periplasmic component
ISU61_16335	COG0791	NLP P60 protein
ISU61_16340	COG1695	Transcriptional regulator
ISU61_16430	COG2944	sequence-specific DNA binding
ISU61_16455	COG0582	viral genome integration into host DNA
ISU61_16475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ISU61_16480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU61_16485	COG4974	Belongs to the 'phage' integrase family
ISU61_16490	COG0716	FMN binding
ISU61_16495	COG4452	Inner membrane protein CreD
ISU61_16500	COG2205	protein histidine kinase activity
ISU61_16505	COG0745	RESPONSE REGULATOR receiver
ISU61_16530	COG1272	protein, Hemolysin III
ISU61_16575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU61_16580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU61_16585	COG0006	proline dipeptidase activity
ISU61_16605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ISU61_16615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISU61_16650	COG0191	fructose-bisphosphate aldolase activity
ISU61_16670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISU61_16675	COG0501	Belongs to the peptidase M48B family
ISU61_16690	COG1166	arginine decarboxylase activity
ISU61_16705	COG2356	endonuclease I
ISU61_16710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ISU61_16715	COG0189	ligase activity
ISU61_16730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU61_16740	COG2805	Type II/IV secretion system protein
ISU61_16745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ISU61_16750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISU61_16755	COG0762	integral membrane protein
ISU61_16765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ISU61_16770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU61_16775	COG3328	transposase activity
ISU61_16800	COG3171	Protein conserved in bacteria
ISU61_16810	COG1194	a g-specific adenine glycosylase
ISU61_16830	COG4774	siderophore transport
ISU61_16835	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_16840	COG1129	ABC transporter
ISU61_16845	COG1879	ABC-type sugar transport system periplasmic component
ISU61_16850	COG1982	Orn Lys Arg decarboxylase major
ISU61_16965	COG3916	Acyl-homoserine-lactone synthase
ISU61_16970	COG2771	luxR family
ISU61_17020	COG2211	Major facilitator Superfamily
ISU61_17035	COG0471	metal ion transport
ISU61_17050	COG3209	COG3209 Rhs family protein
ISU61_17060	COG3501	Rhs element vgr protein
ISU61_17075	COG2610	gluconate transmembrane transporter activity
ISU61_17090	COG1132	(ABC) transporter
ISU61_17135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU61_17135	COG3433	isochorismatase activity
ISU61_17135	COG2226	methyltransferase
ISU61_17145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU61_17145	COG2226	methyltransferase
ISU61_17145	COG3433	isochorismatase activity
ISU61_17150	COG4771	TonB-dependent receptor
ISU61_17155	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU61_17160	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ISU61_17205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU61_17210	COG5001	Diguanylate cyclase
ISU61_17285	COG3501	Rhs element vgr protein
ISU61_17330	COG3501	Rhs element vgr protein
ISU61_17340	COG3209	COG3209 Rhs family protein
ISU61_17360	COG0673	inositol 2-dehydrogenase activity
ISU61_17365	COG2207	Transcriptional regulator
ISU61_17365	COG1917	Cupin 2, conserved barrel domain protein
ISU61_17370	COG1869	D-ribose catabolic process
ISU61_17375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU61_17380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ISU61_17385	COG0431	NADPH-dependent FMN reductase
ISU61_17400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU61_17415	COG3077	Addiction module antitoxin, RelB DinJ family
ISU61_17420	COG2252	PERMEase
ISU61_17425	COG0025	NhaP-type Na H and K H
ISU61_17435	COG1560	Kdo2-lipid A biosynthetic process
ISU61_17445	COG1129	ABC transporter
ISU61_17450	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_17460	COG1069	ribulokinase activity
ISU61_17470	COG0625	glutathione transferase activity
ISU61_17490	COG1278	Cold shock
ISU61_17495	COG1278	Cold shock
ISU61_17500	COG3133	Outer membrane lipoprotein
ISU61_17505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU61_17515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU61_17545	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ISU61_17550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU61_17560	COG4145	pantothenate transmembrane transporter activity
ISU61_17565	COG3924	membrane
ISU61_17575	COG0439	Biotin carboxylase
ISU61_17580	COG0511	ligase activity, forming carbon-carbon bonds
ISU61_17595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ISU61_17600	COG0604	alcohol dehydrogenase
ISU61_17605	COG2200	EAL domain
ISU61_17605	COG2199	diguanylate cyclase activity
ISU61_17610	COG1077	Cell shape determining protein MreB Mrl
ISU61_17615	COG1792	Involved in formation and maintenance of cell shape
ISU61_17620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ISU61_17625	COG0424	maF-like protein
ISU61_17630	COG1530	ribonuclease E activity
ISU61_17635	COG3164	Protein of unknown function
ISU61_17640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU61_17645	COG0312	modulator of DNA gyrase
ISU61_17695	COG0583	DNA-binding transcription factor activity
ISU61_17725	COG2732	(Barnase) inhibitor
ISU61_17735	COG0312	modulator of DNA gyrase
ISU61_17745	COG3783	Cytochrome b(562)
ISU61_17750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU61_17755	COG0366	Alpha amylase catalytic
ISU61_17760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU61_17760	COG1263	PTS System
ISU61_17765	COG1609	Transcriptional regulator
ISU61_17790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU61_17810	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ISU61_17815	COG1137	ATPase activity
ISU61_17820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ISU61_17825	COG3117	lipopolysaccharide transmembrane transporter activity
ISU61_17830	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ISU61_17835	COG0517	IMP dehydrogenase activity
ISU61_17835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISU61_17840	COG0530	calcium, potassium:sodium antiporter activity
ISU61_17845	COG1127	ABC transporter
ISU61_17850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ISU61_17855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU61_17860	COG2854	intermembrane phospholipid transfer
ISU61_17865	COG3113	response to antibiotic
ISU61_17870	COG5007	Belongs to the BolA IbaG family
ISU61_17880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU61_17895	COG0473	3-isopropylmalate dehydrogenase activity
ISU61_17925	COG2814	Major facilitator Superfamily
ISU61_17935	COG4143	(ABC) transporter
ISU61_17940	COG1178	ABC-type Fe3 transport system permease component
ISU61_17945	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ISU61_17950	COG0586	Pfam SNARE associated Golgi protein
ISU61_17955	COG0417	DNA replication proofreading
ISU61_17975	COG2885	chlorophyll binding
ISU61_17975	COG3047	cAMP biosynthetic process
ISU61_18060	COG0564	pseudouridine synthase activity
ISU61_18065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ISU61_18110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ISU61_18120	COG2966	Psort location CytoplasmicMembrane, score
ISU61_18125	COG1280	lysine exporter protein (LysE YggA)
ISU61_18130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISU61_18155	COG1047	Peptidyl-prolyl cis-trans
ISU61_18170	COG0196	riboflavin kinase activity
ISU61_18180	COG0583	DNA-binding transcription factor activity
ISU61_18200	COG1584	GPR1 FUN34 yaaH family protein
ISU61_18215	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISU61_18255	COG0745	RESPONSE REGULATOR receiver
ISU61_18260	COG3045	CreA protein
ISU61_18265	COG3708	Transcriptional regulator
ISU61_18265	COG2207	Transcriptional regulator
ISU61_18280	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ISU61_18285	COG0741	lytic transglycosylase activity
ISU61_18300	COG2199	diguanylate cyclase activity
ISU61_18305	COG2885	chlorophyll binding
ISU61_18310	COG0488	(ABC) transporter
ISU61_18330	COG0560	Phosphoserine phosphatase
ISU61_18335	COG3726	membrane protein affecting hemolysin expression
ISU61_18360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU61_18365	COG0084	hydrolase, TatD family'
ISU61_18370	COG4667	esterase of the alpha-beta hydrolase superfamily
ISU61_18380	COG2823	Periplasmic or secreted lipoprotein
ISU61_18390	COG0456	acetyltransferase
ISU61_18395	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ISU61_18435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU61_18440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU61_18455	COG0859	PFAM glycosyl transferase family 9
ISU61_18465	COG2390	Transcriptional regulator
ISU61_18510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU61_18510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU61_18510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU61_18515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU61_18520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU61_18525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU61_18530	COG2207	Transcriptional regulator
ISU61_18540	COG4269	membrane
ISU61_18595	COG1401	restriction endodeoxyribonuclease activity
ISU61_18610	COG0494	nUDIX hydrolase
ISU61_18640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ISU61_18645	COG0849	cell division
ISU61_18650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ISU61_18670	COG0772	Belongs to the SEDS family
ISU61_18685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ISU61_18690	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ISU61_18695	COG0768	penicillin binding
ISU61_18700	COG3116	cell division
ISU61_18725	COG1609	Transcriptional regulator
ISU61_18740	COG0028	Belongs to the TPP enzyme family
ISU61_18745	COG1022	Amp-dependent synthetase and ligase
ISU61_18765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU61_18770	COG3105	Protein conserved in bacteria
ISU61_18775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISU61_18795	COG0625	glutathione transferase activity
ISU61_18800	COG2969	positive regulation of protein catabolic process
ISU61_18810	COG0493	'glutamate synthase
ISU61_18815	COG0069	glutamate synthase activity
ISU61_18815	COG0067	glutamate synthase
ISU61_18815	COG0070	glutamate synthase
ISU61_18820	COG1242	4 iron, 4 sulfur cluster binding
ISU61_18825	COG5002	protein histidine kinase activity
ISU61_18825	COG2198	Histidine kinase
ISU61_18825	COG0784	Response regulator, receiver
ISU61_18830	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ISU61_18840	COG2823	Periplasmic or secreted lipoprotein
ISU61_18860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ISU61_18870	COG1741	Belongs to the pirin family
ISU61_18875	COG0583	DNA-binding transcription factor activity
ISU61_18900	COG0805	protein transport
ISU61_18910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU61_18930	COG1322	Protein conserved in bacteria
ISU61_18935	COG0586	Pfam SNARE associated Golgi protein
ISU61_18940	COG1966	Carbon starvation protein
ISU61_18955	COG0412	Dienelactone hydrolase
ISU61_18965	COG0583	DNA-binding transcription factor activity
ISU61_18970	COG0697	spore germination
ISU61_18975	COG0679	Auxin Efflux Carrier
ISU61_18980	COG0584	glycerophosphoryl diester phosphodiesterase
ISU61_19040	COG0410	ABC transporter
ISU61_19050	COG4177	L-phenylalanine transmembrane transporter activity
ISU61_19060	COG0683	leucine binding
ISU61_19080	COG2177	Part of the ABC transporter FtsEX involved in
ISU61_19085	COG2884	Cell division ATP-binding protein ftsE
ISU61_19090	COG0552	protein localization to endoplasmic reticulum
ISU61_19090	COG0552	protein localization to endoplasmic reticulum
ISU61_19095	COG0742	ribosomal rna small subunit methyltransferase
ISU61_19100	COG3776	membrane
ISU61_19115	COG3714	YhhN family
ISU61_19130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ISU61_19140	COG0247	lactate metabolic process
ISU61_19150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU61_19155	COG0584	glycerophosphoryl diester phosphodiesterase
ISU61_19165	COG0561	phosphatase activity
ISU61_19170	COG2267	carboxylic ester hydrolase activity
ISU61_19175	COG1280	lysine exporter protein (LysE YggA)
ISU61_19180	COG1280	lysine exporter protein (LysE YggA)
ISU61_19185	COG0514	ATP-dependent DNA helicase (RecQ)
ISU61_19190	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ISU61_19195	COG2050	protein possibly involved in aromatic compounds catabolism
ISU61_19210	COG5564	TIM-barrel signal transduction protein
ISU61_19215	COG5441	Belongs to the UPF0261 family
ISU61_19225	COG0210	DNA helicase
ISU61_19230	COG1011	Hydrolase
ISU61_19235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ISU61_19240	COG3159	Protein conserved in bacteria
ISU61_19260	COG3072	Adenylate cyclase
ISU61_19275	COG1587	Uroporphyrinogen-III synthase
ISU61_19280	COG2959	enzyme of heme biosynthesis
ISU61_19285	COG3071	HemY protein
ISU61_19315	COG1113	amino acid transport
ISU61_19335	COG2244	polysaccharide biosynthetic process
ISU61_19340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ISU61_19345	COG0456	acetyltransferase
ISU61_19350	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ISU61_19355	COG1088	dTDP-glucose 4,6-dehydratase activity
ISU61_19360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ISU61_19365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ISU61_19370	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU61_19375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ISU61_19380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ISU61_19385	COG3118	belongs to the thioredoxin family
ISU61_19410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU61_19425	COG3121	Chaperone
ISU61_19440	COG3121	Chaperone
ISU61_19490	COG0583	DNA-binding transcription factor activity
ISU61_19530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU61_19535	COG3978	acetolactate synthase activity
ISU61_19555	COG3085	chromosome segregation
ISU61_19565	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_19570	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU61_19575	COG1129	ABC transporter
ISU61_19580	COG1879	ABC-type sugar transport system periplasmic component
ISU61_19650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU61_19650	COG0678	peroxiredoxin activity
ISU61_19655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU61_19680	COG1629	transport
ISU61_19695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ISU61_19720	COG0527	aspartate kinase activity
ISU61_19720	COG0460	homoserine dehydrogenase
ISU61_19725	COG0626	cystathionine gamma-synthase activity
ISU61_19735	COG4682	membrane
ISU61_19745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ISU61_19750	COG1609	Transcriptional regulator
ISU61_19755	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU61_19770	COG1575	Belongs to the MenA family. Type 1 subfamily
ISU61_19810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ISU61_19815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU61_19820	COG1494	fructose-1,6-bisphosphatase
ISU61_19830	COG3152	Membrane
ISU61_19845	COG0583	DNA-binding transcription factor activity
ISU61_19850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ISU61_19855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISU61_19860	COG0471	metal ion transport
ISU61_19870	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ISU61_19895	COG3678	ATP-independent chaperone mediated protein folding
ISU61_19900	COG0745	RESPONSE REGULATOR receiver
ISU61_19905	COG2205	protein histidine kinase activity
ISU61_19910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU61_19910	COG2169	Transcriptional regulator
ISU61_19915	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ISU61_19920	COG1045	serine acetyltransferase
ISU61_19935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU61_19940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISU61_19950	COG4942	peptidase
ISU61_19965	COG0156	8-amino-7-oxononanoate synthase activity
ISU61_19975	COG0859	PFAM glycosyl transferase family 9
ISU61_19980	COG0859	PFAM glycosyl transferase family 9
ISU61_19985	COG1519	Transferase
ISU61_20020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ISU61_20045	COG1561	YicC-like family, N-terminal region
ISU61_20050	COG2860	membrane
ISU61_20070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU61_20075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU61_20080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ISU61_20090	COG0786	glutamate:sodium symporter activity
ISU61_20095	COG2233	PERMEase
ISU61_20100	COG2982	Protein involved in outer membrane biogenesis
ISU61_20105	COG0456	acetyltransferase
ISU61_20130	COG1011	Hydrolase
ISU61_20140	COG0174	glutamine synthetase
ISU61_20145	COG3852	Histidine kinase
ISU61_20155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU61_20170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU61_20170	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU61_20175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU61_20180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ISU61_20185	COG3084	Protein conserved in bacteria
ISU61_20195	COG1763	Mo-molybdopterin cofactor biosynthetic process
ISU61_20200	COG3328	transposase activity
ISU61_20225	COG2186	Transcriptional regulator
ISU61_20230	COG0477	Major facilitator Superfamily
ISU61_20245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU61_20275	COG1522	sequence-specific DNA binding
ISU61_20280	COG0716	FMN binding
ISU61_20295	COG3312	ion transport
ISU61_20350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ISU61_20355	COG0573	inorganic phosphate transmembrane transporter activity
ISU61_20360	COG0581	inorganic phosphate transmembrane transporter activity
ISU61_20370	COG0704	Plays a role in the regulation of phosphate uptake
ISU61_20380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU61_20385	COG0765	amino acid transport
ISU61_20390	COG0765	amino acid transport
ISU61_20395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU61_20405	COG2252	PERMEase
ISU61_20435	COG0706	membrane insertase activity
ISU61_20450	COG0230	Belongs to the bacterial ribosomal protein bL34 family