locus-tag	class	description
ISU60_00010	COG0592	DNA-directed DNA polymerase activity
ISU60_00025	COG0187	DNA topoisomerase II activity
ISU60_00030	COG0561	phosphatase activity
ISU60_00040	COG2423	ornithine cyclodeaminase activity
ISU60_00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISU60_00055	COG5645	(Lipo)protein
ISU60_00075	COG3977	Valine--pyruvate aminotransferase
ISU60_00085	COG0366	Alpha amylase catalytic
ISU60_00100	COG2885	chlorophyll binding
ISU60_00110	COG2818	Glycosylase
ISU60_00135	COG2213	PTS system mannitol-specific
ISU60_00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU60_00145	COG3722	fumarate hydratase activity
ISU60_00170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ISU60_00185	COG0437	4 iron, 4 sulfur cluster binding
ISU60_00190	COG2864	formate dehydrogenase
ISU60_00205	COG3276	selenocysteine insertion sequence binding
ISU60_00250	COG3274	enterobacterial common antigen metabolic process
ISU60_00265	COG3121	Chaperone
ISU60_00275	COG1070	Carbohydrate kinase
ISU60_00285	COG4213	ABC transporter substrate-binding protein
ISU60_00295	COG4214	carbohydrate transport
ISU60_00300	COG2207	Transcriptional regulator
ISU60_00300	COG1609	Transcriptional regulator
ISU60_00310	COG0582	viral genome integration into host DNA
ISU60_00355	COG4604	ABC transporter, ATP-binding protein
ISU60_00360	COG4605	iron ion homeostasis
ISU60_00370	COG4607	ABC-type enterochelin transport system periplasmic component
ISU60_00400	COG2986	histidine ammonia-lyase
ISU60_00415	COG2194	sulfuric ester hydrolase activity
ISU60_00420	COG2197	response regulator
ISU60_00445	COG2271	Major facilitator Superfamily
ISU60_00460	COG2831	hemolysin activation secretion protein
ISU60_00465	COG0747	negative chemotaxis
ISU60_00470	COG0601	transmembrane transport
ISU60_00475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU60_00480	COG0444	Belongs to the ABC transporter superfamily
ISU60_00485	COG4608	Belongs to the ABC transporter superfamily
ISU60_00490	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ISU60_00495	COG2199	diguanylate cyclase activity
ISU60_00495	COG2200	EAL domain
ISU60_00500	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU60_00520	COG0612	Peptidase, M16
ISU60_00525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU60_00530	COG1942	4-Oxalocrotonate Tautomerase
ISU60_00535	COG2200	EAL domain
ISU60_00540	COG2982	Protein involved in outer membrane biogenesis
ISU60_00545	COG2134	cdp-diacylglycerol pyrophosphatase
ISU60_00550	COG1295	ribonuclease BN
ISU60_00575	COG1929	Belongs to the glycerate kinase type-1 family
ISU60_00580	COG2610	gluconate transmembrane transporter activity
ISU60_00590	COG3835	regulator
ISU60_00595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU60_00600	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ISU60_00605	COG0339	signal peptide processing
ISU60_00625	COG0589	response to stress
ISU60_00640	COG0306	phosphate transporter
ISU60_00645	COG2081	HI0933 family
ISU60_00660	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_00675	COG0191	fructose-bisphosphate aldolase activity
ISU60_00695	COG1741	Belongs to the pirin family
ISU60_00700	COG1609	Transcriptional regulator
ISU60_00705	COG2610	gluconate transmembrane transporter activity
ISU60_00710	COG3265	gluconokinase activity
ISU60_00725	COG2095	MarC family integral membrane protein
ISU60_00730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU60_00765	COG3275	phosphorelay sensor kinase activity
ISU60_00790	COG0058	SHG alpha-glucan phosphorylase activity
ISU60_00795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU60_00820	COG1349	DNA-binding transcription factor activity
ISU60_00840	COG0058	SHG alpha-glucan phosphorylase activity
ISU60_00845	COG0058	SHG alpha-glucan phosphorylase activity
ISU60_00850	COG1640	4-alpha-glucanotransferase
ISU60_00885	COG1918	ferrous iron import across plasma membrane
ISU60_00890	COG2183	response to ionizing radiation
ISU60_00895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU60_00920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ISU60_00925	COG1011	Hydrolase
ISU60_00935	COG0494	nUDIX hydrolase
ISU60_00940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ISU60_00965	COG4796	Type ii and iii secretion system protein
ISU60_00990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISU60_00995	COG0546	phosphoglycolate phosphatase activity
ISU60_01000	COG0180	Tryptophanyl-tRNA synthetase
ISU60_01020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISU60_01025	COG0402	S-adenosylhomocysteine deaminase activity
ISU60_01045	COG1486	melibiose metabolic process
ISU60_01050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU60_01055	COG0433	COG0433 Predicted ATPase
ISU60_01070	COG1289	transmembrane transporter activity
ISU60_01080	COG1765	OsmC-like protein
ISU60_01090	COG3954	Phosphoribulokinase
ISU60_01100	COG0429	hydrolase of the alpha beta-hydrolase fold
ISU60_01110	COG4521	taurine ABC transporter
ISU60_01120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU60_01125	COG2175	clavaminate synthase activity
ISU60_01135	COG1216	Glycosyl transferase, family 2
ISU60_01155	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ISU60_01160	COG1047	Peptidyl-prolyl cis-trans
ISU60_01170	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU60_01175	COG2964	Protein conserved in bacteria
ISU60_01195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ISU60_01200	COG0049	tRNA binding
ISU60_01240	COG0051	transcription antitermination factor activity, RNA binding
ISU60_01255	COG0089	rRNA binding
ISU60_01265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ISU60_01275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ISU60_01280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ISU60_01290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ISU60_01295	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ISU60_01335	COG1841	ribosomal large subunit assembly
ISU60_01345	COG0201	protein transport
ISU60_01350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU60_01365	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ISU60_01380	COG0789	Transcriptional regulator
ISU60_01385	COG3036	rescue of stalled ribosome
ISU60_01415	COG0758	DNA mediated transformation
ISU60_01425	COG0551	DNA topoisomerase type I activity
ISU60_01440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISU60_01490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ISU60_01495	COG2224	Isocitrate lyase
ISU60_01525	COG0527	aspartate kinase activity
ISU60_01540	COG3833	ABC-type maltose transport systems, permease component
ISU60_01545	COG1175	transmembrane transport
ISU60_01675	COG3501	Rhs element vgr protein
ISU60_01720	COG3501	Rhs element vgr protein
ISU60_01730	COG3209	COG3209 Rhs family protein
ISU60_01750	COG0673	inositol 2-dehydrogenase activity
ISU60_01755	COG1917	Cupin 2, conserved barrel domain protein
ISU60_01755	COG2207	Transcriptional regulator
ISU60_01760	COG1869	D-ribose catabolic process
ISU60_01765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU60_01770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ISU60_01775	COG0431	NADPH-dependent FMN reductase
ISU60_01780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISU60_01790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU60_01805	COG3077	Addiction module antitoxin, RelB DinJ family
ISU60_01810	COG2252	PERMEase
ISU60_01815	COG0025	NhaP-type Na H and K H
ISU60_01825	COG1560	Kdo2-lipid A biosynthetic process
ISU60_01835	COG1129	ABC transporter
ISU60_01840	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_01850	COG1069	ribulokinase activity
ISU60_01860	COG0625	glutathione transferase activity
ISU60_01880	COG1278	Cold shock
ISU60_01885	COG1278	Cold shock
ISU60_01890	COG3133	Outer membrane lipoprotein
ISU60_01895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU60_01905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU60_01935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ISU60_01940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU60_01950	COG4145	pantothenate transmembrane transporter activity
ISU60_01955	COG3924	membrane
ISU60_01965	COG0439	Biotin carboxylase
ISU60_01970	COG0511	ligase activity, forming carbon-carbon bonds
ISU60_01985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ISU60_01990	COG0604	alcohol dehydrogenase
ISU60_01995	COG2199	diguanylate cyclase activity
ISU60_01995	COG2200	EAL domain
ISU60_02000	COG1077	Cell shape determining protein MreB Mrl
ISU60_02005	COG1792	Involved in formation and maintenance of cell shape
ISU60_02010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ISU60_02015	COG0424	maF-like protein
ISU60_02020	COG1530	ribonuclease E activity
ISU60_02025	COG3164	Protein of unknown function
ISU60_02030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU60_02035	COG0312	modulator of DNA gyrase
ISU60_02085	COG0583	DNA-binding transcription factor activity
ISU60_02115	COG2732	(Barnase) inhibitor
ISU60_02125	COG0312	modulator of DNA gyrase
ISU60_02135	COG3783	Cytochrome b(562)
ISU60_02140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU60_02145	COG0366	Alpha amylase catalytic
ISU60_02150	COG1263	PTS System
ISU60_02150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU60_02155	COG1609	Transcriptional regulator
ISU60_02180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU60_02200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ISU60_02205	COG1137	ATPase activity
ISU60_02210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ISU60_02215	COG3117	lipopolysaccharide transmembrane transporter activity
ISU60_02220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ISU60_02225	COG0517	IMP dehydrogenase activity
ISU60_02225	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISU60_02230	COG0530	calcium, potassium:sodium antiporter activity
ISU60_02235	COG1127	ABC transporter
ISU60_02240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ISU60_02245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU60_02250	COG2854	intermembrane phospholipid transfer
ISU60_02255	COG3113	response to antibiotic
ISU60_02260	COG5007	Belongs to the BolA IbaG family
ISU60_02270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU60_02280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU60_02285	COG3105	Protein conserved in bacteria
ISU60_02290	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISU60_02310	COG0625	glutathione transferase activity
ISU60_02315	COG2969	positive regulation of protein catabolic process
ISU60_02325	COG0493	'glutamate synthase
ISU60_02330	COG0070	glutamate synthase
ISU60_02330	COG0069	glutamate synthase activity
ISU60_02330	COG0067	glutamate synthase
ISU60_02335	COG1242	4 iron, 4 sulfur cluster binding
ISU60_02340	COG2198	Histidine kinase
ISU60_02340	COG5002	protein histidine kinase activity
ISU60_02340	COG0784	Response regulator, receiver
ISU60_02345	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ISU60_02355	COG2823	Periplasmic or secreted lipoprotein
ISU60_02375	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ISU60_02385	COG1741	Belongs to the pirin family
ISU60_02390	COG0583	DNA-binding transcription factor activity
ISU60_02435	COG1459	type II secretion system
ISU60_02440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU60_02445	COG4969	Belongs to the N-Me-Phe pilin family
ISU60_02455	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU60_02460	COG3725	Membrane protein required for beta-lactamase induction
ISU60_02465	COG1113	amino acid transport
ISU60_02470	COG2186	Transcriptional regulator
ISU60_02475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ISU60_02480	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU60_02485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU60_02495	COG1049	propionate catabolic process, 2-methylcitrate cycle
ISU60_02505	COG0697	spore germination
ISU60_02525	COG2132	Multicopper oxidase
ISU60_02530	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ISU60_02535	COG0288	reversible hydration of carbon dioxide
ISU60_02540	COG1131	(ABC) transporter
ISU60_02545	COG0842	Transport permease protein
ISU60_02570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ISU60_02575	COG0617	tRNA 3'-terminal CCA addition
ISU60_02580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ISU60_02595	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ISU60_02600	COG1643	Atp-dependent helicase
ISU60_02605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISU60_02610	COG1120	ATPase activity
ISU60_02615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU60_02620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU60_02640	COG2860	membrane
ISU60_02660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU60_02665	COG4999	Histidine kinase
ISU60_02665	COG3850	Histidine kinase
ISU60_02665	COG2205	protein histidine kinase activity
ISU60_02665	COG3437	response regulator, receiver
ISU60_02675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ISU60_02680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU60_02685	COG3956	TIGRFAM MazG family protein
ISU60_02705	COG0602	queuosine metabolic process
ISU60_02710	COG0720	synthase
ISU60_02765	COG0529	Catalyzes the synthesis of activated sulfate
ISU60_02805	COG4942	peptidase
ISU60_02805	COG1388	LysM domain
ISU60_02810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISU60_02820	COG0698	ribose 5-phosphate isomerase
ISU60_02825	COG1063	alcohol dehydrogenase
ISU60_02830	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_02835	COG2376	Dihydroxyacetone kinase
ISU60_02850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISU60_02870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_02875	COG1858	cytochrome C peroxidase
ISU60_02885	COG4771	TonB-dependent receptor
ISU60_02895	COG0024	Methionine aminopeptidase
ISU60_02905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU60_02905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU60_02910	COG1070	Carbohydrate kinase
ISU60_02915	COG3623	hexulose-6-phosphate isomerase
ISU60_02920	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_02925	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_02930	COG1129	ABC transporter
ISU60_02945	COG1349	DNA-binding transcription factor activity
ISU60_02950	COG0235	Class ii aldolase
ISU60_02955	COG0243	molybdopterin cofactor binding
ISU60_02960	COG0437	4 iron, 4 sulfur cluster binding
ISU60_02965	COG3302	dmso reductase anchor subunit
ISU60_02970	COG3381	protein complex oligomerization
ISU60_02975	COG3038	cytochrome b561
ISU60_02980	COG3783	Cytochrome b(562)
ISU60_02990	COG1879	ABC-type sugar transport system periplasmic component
ISU60_03000	COG1129	ABC transporter
ISU60_03005	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_03010	COG3959	Transketolase, thiamine diphosphate binding domain
ISU60_03015	COG3958	Transketolase
ISU60_03020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU60_03060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ISU60_03090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU60_03095	COG1238	metal cluster binding
ISU60_03100	COG2918	glutathione biosynthetic process
ISU60_03115	COG4536	flavin adenine dinucleotide binding
ISU60_03120	COG4137	Cytochrome C assembly protein
ISU60_03125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ISU60_03155	COG3137	Salt-induced outer membrane protein
ISU60_03165	COG3279	Response regulator of the LytR AlgR family
ISU60_03170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU60_03175	COG1605	Chorismate mutase
ISU60_03175	COG0287	Prephenate dehydrogenase
ISU60_03205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISU60_03210	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU60_03215	COG0564	pseudouridine synthase activity
ISU60_03225	COG0542	response to heat
ISU60_03255	COG5544	Lipoprotein
ISU60_03260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISU60_03265	COG1042	CoA-binding domain protein
ISU60_03265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU60_03265	COG0045	succinate-CoA ligase (ADP-forming) activity
ISU60_03270	COG3148	PFAM DTW domain containing protein
ISU60_03275	COG3118	belongs to the thioredoxin family
ISU60_03280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU60_03285	COG2814	Major facilitator Superfamily
ISU60_03290	COG1566	PFAM secretion protein HlyD family protein
ISU60_03295	COG1846	Transcriptional regulator
ISU60_03305	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ISU60_03310	COG2814	Major facilitator Superfamily
ISU60_03345	COG0765	amino acid transport
ISU60_03355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU60_03370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU60_03395	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ISU60_03405	COG1960	acyl-CoA dehydrogenase activity
ISU60_03415	COG0121	glutamine amidotransferase
ISU60_03420	COG3034	peptidoglycan biosynthetic process
ISU60_03430	COG1805	sodium ion transport
ISU60_03435	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU60_03455	COG1477	protein flavinylation
ISU60_03475	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU60_03480	COG0583	DNA-binding transcription factor activity
ISU60_03530	COG2226	methyltransferase
ISU60_03555	COG1940	carbohydrate kinase activity
ISU60_03560	COG0419	ATPase involved in DNA repair
ISU60_03565	COG0420	3'-5' exonuclease activity
ISU60_03570	COG0745	RESPONSE REGULATOR receiver
ISU60_03575	COG5002	protein histidine kinase activity
ISU60_03595	COG0366	Alpha amylase catalytic
ISU60_03620	COG0450	alkyl hydroperoxide reductase
ISU60_03640	COG1862	Preprotein translocase
ISU60_03645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU60_03650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU60_03680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU60_03680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU60_03695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ISU60_03700	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ISU60_03715	COG0142	geranyltranstransferase activity
ISU60_03730	COG0693	protein deglycase activity
ISU60_03735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISU60_03745	COG2814	Major facilitator Superfamily
ISU60_03755	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ISU60_03760	COG1845	cytochrome c oxidase, subunit III
ISU60_03765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ISU60_03770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ISU60_03780	COG2223	nitrite transmembrane transporter activity
ISU60_03785	COG3056	Lipoprotein
ISU60_03790	COG0271	Belongs to the BolA IbaG family
ISU60_03810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ISU60_03815	COG0776	regulation of translation
ISU60_03820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU60_03825	COG1555	photosystem II stabilization
ISU60_03830	COG0824	Thioesterase
ISU60_03840	COG4533	DNA binding
ISU60_03855	COG1522	sequence-specific DNA binding
ISU60_03860	COG1132	(ABC) transporter
ISU60_03865	COG1132	(ABC) transporter
ISU60_03870	COG0347	Belongs to the P(II) protein family
ISU60_03875	COG0004	ammonium transporteR
ISU60_03880	COG1946	Acyl-CoA thioesterase
ISU60_03885	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ISU60_03890	COG3695	enzyme binding
ISU60_03915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU60_03925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU60_03930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU60_03935	COG1309	transcriptional regulator
ISU60_03940	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ISU60_03945	COG3264	Mechanosensitive ion channel
ISU60_03945	COG1196	nuclear chromosome segregation
ISU60_03960	COG2832	Protein of unknown function (DUF454)
ISU60_03970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ISU60_04000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU60_04000	COG0543	2 iron, 2 sulfur cluster binding
ISU60_04020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU60_04060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU60_04080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU60_04085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU60_04090	COG4651	solute:proton antiporter activity
ISU60_04090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU60_04095	COG2223	nitrite transmembrane transporter activity
ISU60_04110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISU60_04115	COG3735	TraB family
ISU60_04120	COG2217	Heavy metal translocating P-type atpase
ISU60_04125	COG0789	Transcriptional regulator
ISU60_04130	COG1585	Membrane protein implicated in regulation of membrane protease activity
ISU60_04135	COG0330	HflC and HflK could
ISU60_04140	COG3118	belongs to the thioredoxin family
ISU60_04145	COG0300	oxidoreductase activity
ISU60_04150	COG2755	lipolytic protein G-D-S-L family
ISU60_04155	COG4181	ATPase activity
ISU60_04160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ISU60_04165	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ISU60_04170	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ISU60_04180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU60_04195	COG2501	S4 domain
ISU60_04230	COG0582	viral genome integration into host DNA
ISU60_04240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ISU60_04245	COG4589	Belongs to the CDS family
ISU60_04255	COG2267	carboxylic ester hydrolase activity
ISU60_04260	COG0671	phosphoesterase, PA-phosphatase related
ISU60_04260	COG2453	phosphatase
ISU60_04290	COG0667	Aldo Keto reductase
ISU60_04295	COG0656	L-ascorbic acid biosynthetic process
ISU60_04305	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU60_04320	COG3328	transposase activity
ISU60_04380	COG3423	Transcriptional regulator
ISU60_04385	COG4953	penicillin-binding protein 1C
ISU60_04395	COG2373	Large extracellular alpha-helical protein
ISU60_04415	COG3962	Belongs to the TPP enzyme family
ISU60_04430	COG1129	ABC transporter
ISU60_04435	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_04440	COG0673	inositol 2-dehydrogenase activity
ISU60_04445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU60_04455	COG3718	enzyme involved in inositol metabolism
ISU60_04465	COG5265	(ABC) transporter
ISU60_04490	COG2197	response regulator
ISU60_04495	COG1278	Cold shock
ISU60_04505	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU60_04510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU60_04530	COG1686	Belongs to the peptidase S11 family
ISU60_04535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU60_04540	COG0772	Belongs to the SEDS family
ISU60_04545	COG0768	penicillin binding
ISU60_04555	COG0799	negative regulation of ribosome biogenesis
ISU60_04565	COG1466	dna polymerase III delta subunit
ISU60_04580	COG2888	peptidyl-tyrosine sulfation
ISU60_04585	COG1126	abc transporter atp-binding protein
ISU60_04590	COG0765	amino acid transport
ISU60_04595	COG0765	amino acid transport
ISU60_04605	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ISU60_04610	COG4535	Mg2 and Co2 transporter CorC
ISU60_04620	COG1702	phosphate starvation-inducible protein PhoH
ISU60_04625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ISU60_04630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU60_04665	COG0367	asparagine synthase
ISU60_04670	COG0647	UMP catabolic process
ISU60_04675	COG1940	carbohydrate kinase activity
ISU60_04675	COG1846	Transcriptional regulator
ISU60_04680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ISU60_04690	COG1263	PTS System
ISU60_04690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU60_04690	COG2190	(PTS) system
ISU60_04715	COG0735	belongs to the Fur family
ISU60_04730	COG0596	Alpha beta hydrolase
ISU60_04740	COG0582	viral genome integration into host DNA
ISU60_04775	COG2113	Glycine betaine
ISU60_04780	COG4176	ABC-type proline glycine betaine transport system permease component
ISU60_04785	COG4175	Glycine betaine
ISU60_04790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ISU60_04830	COG1278	Cold shock
ISU60_04835	COG0747	negative chemotaxis
ISU60_04845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU60_04850	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ISU60_04855	COG1124	(ABC) transporter
ISU60_04860	COG0831	urea catabolic process
ISU60_04885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ISU60_04895	COG4413	Urea transporter
ISU60_04900	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU60_04910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU60_04920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU60_04930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU60_04935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU60_04940	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISU60_04945	COG1917	Cupin 2, conserved barrel domain protein
ISU60_04945	COG2169	Transcriptional regulator
ISU60_04960	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ISU60_04965	COG0033	Phosphoglucomutase
ISU60_04980	COG0745	RESPONSE REGULATOR receiver
ISU60_04985	COG2205	protein histidine kinase activity
ISU60_05020	COG3272	Protein of unknown function (DUF1722)
ISU60_05030	COG5212	phosphodiesterase
ISU60_05035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ISU60_05050	COG1984	allophanate hydrolase subunit 2
ISU60_05095	COG0513	Belongs to the DEAD box helicase family
ISU60_05105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ISU60_05120	COG3026	antisigma factor binding
ISU60_05125	COG3086	response to oxidative stress
ISU60_05160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ISU60_05175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU60_05180	COG1737	Transcriptional regulator
ISU60_05190	COG0560	Phosphoserine phosphatase
ISU60_05245	COG2205	protein histidine kinase activity
ISU60_05250	COG3170	Tfp pilus assembly protein FimV
ISU60_05255	COG2204	response regulator
ISU60_05260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU60_05260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ISU60_05265	COG0347	Belongs to the P(II) protein family
ISU60_05270	COG2188	Transcriptional regulator
ISU60_05275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU60_05275	COG1017	nitric oxide dioxygenase activity
ISU60_05295	COG2814	Major facilitator Superfamily
ISU60_05300	COG3711	transcriptional antiterminator
ISU60_05305	COG3683	transport system, periplasmic component
ISU60_05310	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU60_05330	COG1104	cysteine desulfurase activity
ISU60_05335	COG0822	iron-sulfur transferase activity
ISU60_05350	COG0443	Heat shock 70 kDa protein
ISU60_05355	COG0633	Ferredoxin
ISU60_05360	COG2975	iron-sulfur cluster assembly
ISU60_05385	COG3468	outer membrane autotransporter barrel domain protein
ISU60_05390	COG3468	outer membrane autotransporter barrel domain protein
ISU60_05430	COG2976	Protein conserved in bacteria
ISU60_05435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU60_05450	COG1645	bacterial-type flagellum-dependent swarming motility
ISU60_05460	COG0517	IMP dehydrogenase activity
ISU60_05460	COG0516	GMP reductase activity
ISU60_05505	COG3328	transposase activity
ISU60_05520	COG0351	phosphomethylpyrimidine kinase
ISU60_05545	COG0826	peptidase U32
ISU60_05550	COG3422	double-strand break repair
ISU60_05555	COG0745	RESPONSE REGULATOR receiver
ISU60_05585	COG3842	ATPase activity
ISU60_05595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISU60_05605	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU60_05610	COG1177	transmembrane transport
ISU60_05615	COG0443	Heat shock 70 kDa protein
ISU60_05620	COG2239	Acts as a magnesium transporter
ISU60_05635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ISU60_05645	COG0581	inorganic phosphate transmembrane transporter activity
ISU60_05660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU60_05665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ISU60_05690	COG1393	Belongs to the ArsC family
ISU60_05695	COG4783	chaperone-mediated protein folding
ISU60_05700	COG0628	permease
ISU60_05710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ISU60_05715	COG2716	regulation of RNA biosynthetic process
ISU60_05725	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ISU60_05740	COG2321	neutral zinc metallopeptidase
ISU60_05760	COG1876	peptidase activity
ISU60_05770	COG1393	Belongs to the ArsC family
ISU60_05785	COG1175	transmembrane transport
ISU60_05790	COG3842	ATPase activity
ISU60_05800	COG3119	arylsulfatase activity
ISU60_05805	COG0641	radical SAM
ISU60_05810	COG1988	membrane-bound metal-dependent
ISU60_05820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU60_05830	COG2197	response regulator
ISU60_05835	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU60_05835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU60_05840	COG3062	negative regulation of establishment of protein localization
ISU60_05850	COG3043	anaerobic respiration
ISU60_05855	COG3005	denitrification pathway
ISU60_05895	COG3111	PFAM Bacterial OB fold (BOF) protein
ISU60_05905	COG2837	iron assimilation
ISU60_05910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISU60_05920	COG4886	Leucine-rich repeat (LRR) protein
ISU60_05930	COG2731	YhcH YjgK YiaL family protein
ISU60_05935	COG1737	Transcriptional regulator
ISU60_05945	COG4150	thiosulfate binding
ISU60_05950	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ISU60_05955	COG4208	sulfate ABC transporter
ISU60_05960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ISU60_05975	COG0745	RESPONSE REGULATOR receiver
ISU60_05980	COG5002	protein histidine kinase activity
ISU60_05980	COG3850	Histidine kinase
ISU60_05990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISU60_06010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ISU60_06025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU60_06030	COG0745	RESPONSE REGULATOR receiver
ISU60_06035	COG2205	protein histidine kinase activity
ISU60_06055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU60_06065	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ISU60_06080	COG3530	Putative quorum-sensing-regulated virulence factor
ISU60_06145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU60_06160	COG0667	Aldo Keto reductase
ISU60_06185	COG0436	Aminotransferase
ISU60_06190	COG3038	cytochrome b561
ISU60_06220	COG3381	protein complex oligomerization
ISU60_06225	COG3302	dmso reductase anchor subunit
ISU60_06230	COG0437	4 iron, 4 sulfur cluster binding
ISU60_06235	COG0243	molybdopterin cofactor binding
ISU60_06270	COG2951	lytic endotransglycosylase activity
ISU60_06330	COG3121	Chaperone
ISU60_06335	COG3188	usher protein
ISU60_06340	COG3328	transposase activity
ISU60_06345	COG3188	usher protein
ISU60_06435	COG2824	Alkylphosphonate utilization operon protein PhnA
ISU60_06445	COG1704	LemA family
ISU60_06465	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU60_06470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU60_06475	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU60_06485	COG1138	Cytochrome C-type biogenesis protein
ISU60_06490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISU60_06495	COG3088	subunit of a heme lyase
ISU60_06495	COG4235	cytochrome complex assembly
ISU60_06500	COG4235	cytochrome complex assembly
ISU60_06500	COG3088	subunit of a heme lyase
ISU60_06515	COG3691	Protein conserved in bacteria
ISU60_06530	COG2062	phosphohistidine phosphatase, SixA
ISU60_06545	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU60_06560	COG0730	response to heat
ISU60_06565	COG3101	peptidyl-lysine hydroxylation
ISU60_06580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU60_06585	COG1794	racemase activity, acting on amino acids and derivatives
ISU60_06600	COG0697	spore germination
ISU60_06615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU60_06625	COG0586	Pfam SNARE associated Golgi protein
ISU60_06635	COG0285	dihydrofolate synthase activity
ISU60_06640	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ISU60_06645	COG1286	toxin biosynthetic process
ISU60_06650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ISU60_06660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_06665	COG4215	(ABC) transporter
ISU60_06670	COG4160	amino acid transport
ISU60_06675	COG4598	ABC transporter
ISU60_06680	COG1090	epimerase
ISU60_06690	COG0622	Phosphoesterase
ISU60_06695	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ISU60_06710	COG3328	transposase activity
ISU60_06725	COG1609	Transcriptional regulator
ISU60_06730	COG0857	belongs to the CobB CobQ family
ISU60_06730	COG0280	phosphate acetyltransferase
ISU60_06750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU60_06755	COG0490	domain, Protein
ISU60_06755	COG0471	metal ion transport
ISU60_06765	COG0436	Aminotransferase
ISU60_06770	COG0583	DNA-binding transcription factor activity
ISU60_06780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU60_06800	COG1034	ATP synthesis coupled electron transport
ISU60_06815	COG0839	Belongs to the complex I subunit 6 family
ISU60_06825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ISU60_06830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU60_06845	COG2731	YhcH YjgK YiaL family protein
ISU60_06850	COG3265	gluconokinase activity
ISU60_06855	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_06860	COG1649	PFAM Uncharacterised BCR, COG1649
ISU60_06865	COG1609	Transcriptional regulator
ISU60_06870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU60_06885	COG0129	dihydroxy-acid dehydratase activity
ISU60_06890	COG4575	ribosome binding
ISU60_06900	COG1169	isochorismate synthase
ISU60_06915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ISU60_06930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISU60_06965	COG1126	abc transporter atp-binding protein
ISU60_06970	COG0765	amino acid transport
ISU60_06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_07005	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ISU60_07025	COG1063	alcohol dehydrogenase
ISU60_07030	COG1879	ABC-type sugar transport system periplasmic component
ISU60_07035	COG1129	ABC transporter
ISU60_07040	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_07045	COG1609	Transcriptional regulator
ISU60_07050	COG0583	DNA-binding transcription factor activity
ISU60_07055	COG0473	3-isopropylmalate dehydrogenase activity
ISU60_07065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU60_07070	COG4638	Rieske (2fe-2S)
ISU60_07075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU60_07080	COG2831	hemolysin activation secretion protein
ISU60_07085	COG3210	domain, Protein
ISU60_07125	COG3210	domain, Protein
ISU60_07135	COG3842	ATPase activity
ISU60_07145	COG1609	Transcriptional regulator
ISU60_07160	COG0395	ABC-type sugar transport system, permease component
ISU60_07165	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ISU60_07185	COG0668	transmembrane transport
ISU60_07190	COG1518	maintenance of DNA repeat elements
ISU60_07195	COG1203	CRISPR-associated helicase, Cas3
ISU60_07220	COG0667	Aldo Keto reductase
ISU60_07230	COG0477	Major facilitator Superfamily
ISU60_07240	COG0583	DNA-binding transcription factor activity
ISU60_07245	COG2771	luxR family
ISU60_07250	COG3916	Acyl-homoserine-lactone synthase
ISU60_07270	COG0628	permease
ISU60_07290	COG3328	transposase activity
ISU60_07310	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ISU60_07320	COG3328	transposase activity
ISU60_07325	COG1530	ribonuclease E activity
ISU60_07330	COG0564	pseudouridine synthase activity
ISU60_07335	COG0424	maF-like protein
ISU60_07340	COG1399	metal-binding, possibly nucleic acid-binding protein
ISU60_07345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ISU60_07375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU60_07385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU60_07390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ISU60_07400	COG0470	DNA polymerase III
ISU60_07405	COG0084	hydrolase, TatD family'
ISU60_07410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU60_07410	COG1263	PTS System
ISU60_07420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISU60_07425	COG0537	adenosine 5'-monophosphoramidase activity
ISU60_07430	COG5633	Lipoprotein
ISU60_07445	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU60_07455	COG1252	NADH dehydrogenase
ISU60_07470	COG3328	transposase activity
ISU60_07475	COG3134	Outer membrane lipoprotein
ISU60_07480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ISU60_07485	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU60_07495	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU60_07500	COG1940	carbohydrate kinase activity
ISU60_07520	COG2850	peptidyl-arginine hydroxylation
ISU60_07530	COG0745	RESPONSE REGULATOR receiver
ISU60_07540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISU60_07560	COG1187	pseudouridine synthase activity
ISU60_07565	COG0538	isocitrate dehydrogenase activity
ISU60_07580	COG0840	transmembrane signaling receptor activity
ISU60_07585	COG0702	epimerase
ISU60_07590	COG1733	regulation of RNA biosynthetic process
ISU60_07615	COG1522	sequence-specific DNA binding
ISU60_07630	COG0604	alcohol dehydrogenase
ISU60_07630	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_07630	COG3321	synthase
ISU60_07655	COG1285	pathogenesis
ISU60_07680	COG1360	Flagellar Motor Protein
ISU60_07685	COG2198	Histidine kinase
ISU60_07685	COG0643	Histidine kinase
ISU60_07690	COG0835	chemotaxis
ISU60_07695	COG2271	Major facilitator Superfamily
ISU60_07700	COG0251	oxidation-reduction process
ISU60_07710	COG2964	Protein conserved in bacteria
ISU60_07730	COG0840	transmembrane signaling receptor activity
ISU60_07735	COG0840	transmembrane signaling receptor activity
ISU60_07740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ISU60_07750	COG0745	RESPONSE REGULATOR receiver
ISU60_07755	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ISU60_07760	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU60_07770	COG5295	Hep Hag repeat protein
ISU60_07780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ISU60_07835	COG3121	Chaperone
ISU60_07855	COG3008	intermembrane lipid transfer
ISU60_07860	COG2995	paraquat-inducible protein a
ISU60_07865	COG1956	GAF domain-containing protein
ISU60_07875	COG0793	Belongs to the peptidase S41A family
ISU60_07885	COG3539	Fimbrial protein
ISU60_07890	COG3121	Chaperone
ISU60_07905	COG3121	Chaperone
ISU60_07910	COG2814	Major facilitator Superfamily
ISU60_07915	COG0823	Involved in the tonB-independent uptake of proteins
ISU60_07925	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU60_07930	COG1823	symporter activity
ISU60_07935	COG1988	membrane-bound metal-dependent
ISU60_07940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU60_07945	COG1653	transport
ISU60_07955	COG0395	ABC-type sugar transport system, permease component
ISU60_07960	COG1175	transmembrane transport
ISU60_07970	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_07980	COG1917	Cupin 2, conserved barrel domain protein
ISU60_07985	COG3328	transposase activity
ISU60_07990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU60_08000	COG3001	Fructosamine kinase
ISU60_08010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU60_08015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU60_08020	COG1121	(ABC) transporter
ISU60_08025	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISU60_08045	COG4249	Peptidase C14 caspase catalytic subunit p20
ISU60_08080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ISU60_08080	COG0072	phenylalanine-tRNA ligase activity
ISU60_08085	COG0776	regulation of translation
ISU60_08100	COG0386	Belongs to the glutathione peroxidase family
ISU60_08150	COG0791	NLP P60 protein
ISU60_08175	COG0574	Belongs to the PEP-utilizing enzyme family
ISU60_08175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU60_08185	COG0628	permease
ISU60_08190	COG0247	lactate metabolic process
ISU60_08190	COG0277	FAD linked oxidase domain protein
ISU60_08195	COG2050	protein possibly involved in aromatic compounds catabolism
ISU60_08200	COG0316	Belongs to the HesB IscA family
ISU60_08205	COG0719	Fe-S assembly protein
ISU60_08210	COG0396	ATPase activity
ISU60_08215	COG0719	Fe-S assembly protein
ISU60_08230	COG1388	LysM domain
ISU60_08230	COG1376	ErfK ybiS ycfS ynhG family protein
ISU60_08280	COG0307	riboflavin synthase, alpha
ISU60_08290	COG2814	Major facilitator Superfamily
ISU60_08295	COG0583	DNA-binding transcription factor activity
ISU60_08315	COG0791	NLP P60 protein
ISU60_08320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ISU60_08330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISU60_08335	COG0346	lactoylglutathione lyase activity
ISU60_08345	COG1902	pentaerythritol trinitrate reductase activity
ISU60_08350	COG1309	transcriptional regulator
ISU60_08355	COG2194	sulfuric ester hydrolase activity
ISU60_08360	COG3313	Fe-S protein
ISU60_08365	COG4989	oxidoreductase activity
ISU60_08375	COG3133	Outer membrane lipoprotein
ISU60_08385	COG3895	Periplasmic Protein
ISU60_08405	COG0625	glutathione transferase activity
ISU60_08420	COG3104	oligopeptide transport
ISU60_08425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU60_08425	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU60_08430	COG4172	Belongs to the ABC transporter superfamily
ISU60_08440	COG4171	peptide transport system, permease
ISU60_08445	COG4168	peptide transport system, permease
ISU60_08450	COG4166	transmembrane transport
ISU60_08460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISU60_08465	COG1842	Phage shock protein A
ISU60_08475	COG1983	PspC domain protein
ISU60_08485	COG3106	COG3106 Predicted ATPase
ISU60_08495	COG5654	RES domain protein
ISU60_08500	COG5642	Protein of unknown function (DUF2384)
ISU60_08515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ISU60_08520	COG4948	Mandelate Racemase Muconate Lactonizing
ISU60_08525	COG2866	Carboxypeptidase
ISU60_08530	COG4166	transmembrane transport
ISU60_08550	COG0657	acetylesterase activity
ISU60_08560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU60_08560	COG1013	pyruvate-flavodoxin oxidoreductase activity
ISU60_08560	COG0674	pyruvate-flavodoxin oxidoreductase activity
ISU60_08560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ISU60_08570	COG1285	pathogenesis
ISU60_08575	COG3042	response to heat
ISU60_08580	COG3187	Heat shock protein
ISU60_08585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU60_08590	COG2911	Protein conserved in bacteria
ISU60_08600	COG3784	Protein of unknown function (DUF1318)
ISU60_08605	COG0246	Mannitol dehydrogenase
ISU60_08610	COG2390	Transcriptional regulator
ISU60_08620	COG1643	Atp-dependent helicase
ISU60_08635	COG3591	Belongs to the peptidase S1B family
ISU60_08645	COG3038	cytochrome b561
ISU60_08670	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ISU60_08675	COG2205	protein histidine kinase activity
ISU60_08680	COG0745	RESPONSE REGULATOR receiver
ISU60_08690	COG0531	amino acid
ISU60_08700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ISU60_08705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ISU60_08710	COG0589	response to stress
ISU60_08715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISU60_08720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU60_08735	COG1011	Hydrolase
ISU60_08740	COG0440	acetolactate synthase activity
ISU60_08745	COG0028	Belongs to the TPP enzyme family
ISU60_08775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ISU60_08785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU60_08805	COG1609	Transcriptional regulator
ISU60_08810	COG0038	chloride channel
ISU60_08815	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ISU60_08820	COG1940	carbohydrate kinase activity
ISU60_08825	COG0583	DNA-binding transcription factor activity
ISU60_08830	COG2814	Major facilitator Superfamily
ISU60_08840	COG0114	fumarate hydratase activity
ISU60_08850	COG5339	Protein conserved in bacteria
ISU60_08860	COG0385	Bile acid
ISU60_08865	COG0673	inositol 2-dehydrogenase activity
ISU60_08875	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_08880	COG1129	ABC transporter
ISU60_08885	COG1879	ABC-type sugar transport system periplasmic component
ISU60_08900	COG2274	protein secretion by the type I secretion system
ISU60_08905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU60_08915	COG1132	(ABC) transporter
ISU60_08945	COG3708	Transcriptional regulator
ISU60_08945	COG2207	Transcriptional regulator
ISU60_08950	COG4658	electron transport chain
ISU60_08955	COG4659	FMN binding
ISU60_08965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ISU60_08970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU60_08975	COG2271	Major facilitator Superfamily
ISU60_08985	COG1966	Carbon starvation protein
ISU60_08990	COG2879	small protein
ISU60_08995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISU60_09015	COG0023	Translation Initiation Factor
ISU60_09030	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ISU60_09035	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ISU60_09040	COG0671	phosphoesterase, PA-phosphatase related
ISU60_09050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISU60_09060	COG0583	DNA-binding transcription factor activity
ISU60_09080	COG0616	signal peptide processing
ISU60_09085	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_09095	COG1187	pseudouridine synthase activity
ISU60_09100	COG0009	L-threonylcarbamoyladenylate synthase
ISU60_09120	COG0512	Glutamine amidotransferase of anthranilate synthase
ISU60_09130	COG0134	indole-3-glycerol-phosphate synthase activity
ISU60_09130	COG0135	phosphoribosylanthranilate isomerase activity
ISU60_09150	COG3047	cAMP biosynthetic process
ISU60_09185	COG3328	transposase activity
ISU60_09190	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ISU60_09195	COG2350	Protein conserved in bacteria
ISU60_09240	COG4608	Belongs to the ABC transporter superfamily
ISU60_09245	COG0444	Belongs to the ABC transporter superfamily
ISU60_09250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU60_09255	COG0601	transmembrane transport
ISU60_09265	COG2095	MarC family integral membrane protein
ISU60_09270	COG1454	alcohol dehydrogenase
ISU60_09270	COG1012	belongs to the aldehyde dehydrogenase family
ISU60_09300	COG0745	RESPONSE REGULATOR receiver
ISU60_09310	COG0788	formyltetrahydrofolate deformylase activity
ISU60_09315	COG3328	transposase activity
ISU60_09320	COG0583	DNA-binding transcription factor activity
ISU60_09325	COG0708	Exodeoxyribonuclease III
ISU60_09330	COG0494	nUDIX hydrolase
ISU60_09340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ISU60_09345	COG0709	Synthesizes selenophosphate from selenide and ATP
ISU60_09350	COG0778	Nitroreductase
ISU60_09355	COG0616	signal peptide processing
ISU60_09360	COG0252	asparaginase activity
ISU60_09365	COG1335	isochorismatase
ISU60_09370	COG3139	Protein of unknown function (DUF1315)
ISU60_09390	COG3713	MltA-interacting MipA family protein
ISU60_09395	COG2766	serine protein kinase
ISU60_09410	COG0583	DNA-binding transcription factor activity
ISU60_09420	COG2814	Major facilitator Superfamily
ISU60_09430	COG2719	SpoVR family
ISU60_09460	COG1104	cysteine desulfurase activity
ISU60_09470	COG3328	transposase activity
ISU60_09630	COG3328	transposase activity
ISU60_09730	COG0582	viral genome integration into host DNA
ISU60_09740	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISU60_09745	COG2951	lytic endotransglycosylase activity
ISU60_09760	COG2894	cell division
ISU60_09765	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ISU60_09770	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ISU60_09775	COG0318	PFAM AMP-dependent synthetase and ligase
ISU60_09785	COG3065	identical protein binding
ISU60_09795	COG1199	ATP-dependent helicase activity
ISU60_09800	COG0251	oxidation-reduction process
ISU60_09815	COG0800	Aldolase
ISU60_09820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ISU60_09825	COG1737	Transcriptional regulator
ISU60_09830	COG0469	pyruvate kinase activity
ISU60_09840	COG1560	Kdo2-lipid A biosynthetic process
ISU60_09845	COG0739	heme binding
ISU60_09850	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ISU60_09860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU60_09885	COG0494	nUDIX hydrolase
ISU60_09895	COG1801	Protein of unknown function DUF72
ISU60_09900	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ISU60_09920	COG3102	Protein conserved in bacteria
ISU60_09940	COG0728	peptidoglycan biosynthetic process
ISU60_09950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU60_09965	COG3381	protein complex oligomerization
ISU60_09980	COG1940	carbohydrate kinase activity
ISU60_09985	COG0584	glycerophosphoryl diester phosphodiesterase
ISU60_10005	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU60_10010	COG3833	ABC-type maltose transport systems, permease component
ISU60_10030	COG0659	secondary active sulfate transmembrane transporter activity
ISU60_10050	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU60_10075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ISU60_10090	COG0012	GTP binding
ISU60_10140	COG5002	protein histidine kinase activity
ISU60_10185	COG0500	methyltransferase
ISU60_10205	COG3328	transposase activity
ISU60_10250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU60_10255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU60_10260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU60_10275	COG0402	S-adenosylhomocysteine deaminase activity
ISU60_10340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU60_10350	COG3850	Histidine kinase
ISU60_10355	COG0387	Pfam Sodium calcium exchanger
ISU60_10360	COG1702	phosphate starvation-inducible protein PhoH
ISU60_10375	COG3658	cytochrome
ISU60_10380	COG1215	transferase activity, transferring glycosyl groups
ISU60_10385	COG0726	polysaccharide deacetylase
ISU60_10385	COG1649	PFAM Uncharacterised BCR, COG1649
ISU60_10390	COG0457	Tetratricopeptide repeat
ISU60_10395	COG0006	proline dipeptidase activity
ISU60_10415	COG1136	(ABC) transporter
ISU60_10415	COG0577	efflux transmembrane transporter activity
ISU60_10425	COG0577	efflux transmembrane transporter activity
ISU60_10425	COG1136	(ABC) transporter
ISU60_10440	COG0672	)-iron permease
ISU60_10455	COG2066	Belongs to the glutaminase family
ISU60_10465	COG1349	DNA-binding transcription factor activity
ISU60_10475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU60_10480	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU60_10495	COG2814	Major facilitator Superfamily
ISU60_10520	COG2030	dehydratase
ISU60_10525	COG0427	acetyl-CoA hydrolase
ISU60_10535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_10535	COG2205	protein histidine kinase activity
ISU60_10550	COG3188	usher protein
ISU60_10560	COG3121	Chaperone
ISU60_10570	COG0582	viral genome integration into host DNA
ISU60_10575	COG1169	isochorismate synthase
ISU60_10580	COG2814	Major facilitator Superfamily
ISU60_10585	COG1132	(ABC) transporter
ISU60_10600	COG2226	methyltransferase
ISU60_10600	COG3433	isochorismatase activity
ISU60_10600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU60_10620	COG1021	2,3-dihydroxybenzoate-AMP ligase
ISU60_10625	COG4771	TonB-dependent receptor
ISU60_10685	COG3842	ATPase activity
ISU60_10690	COG0395	ABC-type sugar transport system, permease component
ISU60_10695	COG1175	transmembrane transport
ISU60_10705	COG0673	inositol 2-dehydrogenase activity
ISU60_10710	COG2188	Transcriptional regulator
ISU60_10835	COG2197	response regulator
ISU60_10845	COG3136	membrane protein required for alginate biosynthesis
ISU60_10865	COG1113	amino acid transport
ISU60_10885	COG2822	iron ion transport
ISU60_10890	COG0672	)-iron permease
ISU60_10905	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU60_10905	COG0506	proline dehydrogenase activity
ISU60_10905	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU60_10920	COG1126	abc transporter atp-binding protein
ISU60_10925	COG0765	amino acid transport
ISU60_10930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_10945	COG1191	sigma factor activity
ISU60_10975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ISU60_10980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ISU60_10985	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ISU60_11005	COG1677	Flagellar hook-basal body complex protein FliE
ISU60_11025	COG1157	protein secretion by the type III secretion system
ISU60_11040	COG1580	Controls the rotational direction of flagella during chemotaxis
ISU60_11065	COG1987	bacterial-type flagellum assembly
ISU60_11085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU60_11090	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_11095	COG1129	ABC transporter
ISU60_11105	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_11110	COG3347	Dehydrogenase
ISU60_11110	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_11115	COG2390	Transcriptional regulator
ISU60_11125	COG1256	bacterial-type flagellum assembly
ISU60_11165	COG1558	bacterial-type flagellum-dependent cell motility
ISU60_11170	COG1815	bacterial-type flagellum-dependent cell motility
ISU60_11180	COG2747	anti-sigma28 factor FlgM
ISU60_11185	COG3418	PFAM FlgN family protein
ISU60_11210	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU60_11215	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU60_11240	COG2372	response to copper ion
ISU60_11245	COG1528	Iron-storage protein
ISU60_11260	COG1770	oligopeptidase
ISU60_11275	COG3141	response to X-ray
ISU60_11280	COG0513	Belongs to the DEAD box helicase family
ISU60_11305	COG1760	l-serine dehydratase
ISU60_11310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISU60_11315	COG2368	4-hydroxyphenylacetate
ISU60_11330	COG3971	2-oxopent-4-enoate hydratase activity
ISU60_11340	COG3384	dioxygenase
ISU60_11345	COG1012	belongs to the aldehyde dehydrogenase family
ISU60_11360	COG1846	Transcriptional regulator
ISU60_11365	COG1253	flavin adenine dinucleotide binding
ISU60_11370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU60_11370	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU60_11375	COG3715	PTS system
ISU60_11380	COG3716	PTS system mannose fructose sorbose family IID component
ISU60_11400	COG5001	Diguanylate cyclase
ISU60_11400	COG5002	protein histidine kinase activity
ISU60_11400	COG3447	MASE1 domain protein
ISU60_11410	COG2226	methyltransferase
ISU60_11415	COG1496	oxidoreductase activity
ISU60_11435	COG1113	amino acid transport
ISU60_11470	COG2207	Transcriptional regulator
ISU60_11480	COG1132	(ABC) transporter
ISU60_11525	COG3328	transposase activity
ISU60_11530	COG2223	nitrite transmembrane transporter activity
ISU60_11550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ISU60_11575	COG3122	Protein conserved in bacteria
ISU60_11595	COG0534	Mate efflux family protein
ISU60_11610	COG4948	Mandelate Racemase Muconate Lactonizing
ISU60_11620	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_11625	COG3011	Protein conserved in bacteria
ISU60_11630	COG2271	Major facilitator Superfamily
ISU60_11640	COG1470	cell adhesion involved in biofilm formation
ISU60_11640	COG1388	LysM domain
ISU60_11645	COG3328	transposase activity
ISU60_11660	COG2925	Exonuclease
ISU60_11670	COG0531	amino acid
ISU60_11675	COG0371	Dehydrogenase
ISU60_11680	COG1129	ABC transporter
ISU60_11685	COG1129	ABC transporter
ISU60_11690	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_11705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU60_11720	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ISU60_11730	COG0131	Imidazoleglycerol-phosphate dehydratase
ISU60_11730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU60_11750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ISU60_11750	COG0140	phosphoribosyl-ATP diphosphatase activity
ISU60_11760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU60_11765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU60_11780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU60_11785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU60_11790	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU60_11795	COG1120	ATPase activity
ISU60_11810	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ISU60_11815	COG0076	glutamate decarboxylase activity
ISU60_11820	COG4114	ferric iron reductase
ISU60_11825	COG1253	flavin adenine dinucleotide binding
ISU60_11830	COG2982	Protein involved in outer membrane biogenesis
ISU60_11845	COG0489	protein tyrosine kinase activity
ISU60_11875	COG2814	Major facilitator Superfamily
ISU60_11885	COG1346	cytolysis
ISU60_11900	COG2949	membrane
ISU60_11905	COG4211	Belongs to the binding-protein-dependent transport system permease family
ISU60_11920	COG2311	Membrane
ISU60_11930	COG0477	Major facilitator Superfamily
ISU60_11935	COG0583	DNA-binding transcription factor activity
ISU60_11965	COG1136	(ABC) transporter
ISU60_11975	COG0303	'Molybdopterin
ISU60_11985	COG3328	transposase activity
ISU60_11995	COG0488	(ABC) transporter
ISU60_12125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISU60_12130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ISU60_12140	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_12145	COG1024	Enoyl-CoA hydratase
ISU60_12155	COG3425	synthase
ISU60_12160	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_12165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU60_12170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ISU60_12180	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_12205	COG2920	part of a sulfur-relay system
ISU60_12225	COG1832	CoA-binding protein
ISU60_12240	COG0210	DNA helicase
ISU60_12245	COG3304	Inner membrane component domain
ISU60_12250	COG1289	transmembrane transporter activity
ISU60_12255	COG3070	regulator of competence-specific genes
ISU60_12280	COG1067	ATP-dependent peptidase activity
ISU60_12320	COG3130	regulation of translation
ISU60_12325	COG3009	Protein conserved in bacteria
ISU60_12335	COG3008	intermembrane lipid transfer
ISU60_12335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU60_12340	COG2995	paraquat-inducible protein a
ISU60_12345	COG0488	(ABC) transporter
ISU60_12355	COG3217	Mosc domain protein beta barrel domain protein
ISU60_12355	COG0633	Ferredoxin
ISU60_12370	COG0308	aminopeptidase N
ISU60_12390	COG1448	Aminotransferase
ISU60_12400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU60_12405	COG3108	Peptidase M15
ISU60_12410	COG2989	Protein conserved in bacteria
ISU60_12435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISU60_12440	COG3173	Aminoglycoside phosphotransferase
ISU60_12455	COG1278	Cold shock
ISU60_12460	COG5383	Protein conserved in bacteria
ISU60_12475	COG0658	competence protein
ISU60_12475	COG2333	competence protein COMEC
ISU60_12485	COG0539	negative regulation of cytoplasmic translation
ISU60_12510	COG5295	Hep Hag repeat protein
ISU60_12510	COG5295	Hep Hag repeat protein
ISU60_12515	COG0252	asparaginase activity
ISU60_12520	COG1944	ATP diphosphatase activity
ISU60_12525	COG2116	formate transmembrane transporter activity
ISU60_12530	COG1882	Formate acetyltransferase
ISU60_12540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISU60_12555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ISU60_12565	COG3107	peptidoglycan biosynthetic process
ISU60_12565	COG1674	ftsk spoiiie
ISU60_12575	COG0492	ferredoxin-NADP+ reductase activity
ISU60_12585	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ISU60_12595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ISU60_12605	COG0542	response to heat
ISU60_12615	COG1278	Cold shock
ISU60_12625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU60_12630	COG2990	Protein conserved in bacteria
ISU60_12635	COG3593	DNA synthesis involved in DNA repair
ISU60_12640	COG2431	L-lysine efflux transmembrane transporter activity
ISU60_12650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU60_12655	COG0028	Belongs to the TPP enzyme family
ISU60_12665	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ISU60_12670	COG0702	epimerase
ISU60_12675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU60_12685	COG1605	Chorismate mutase
ISU60_12690	COG1126	abc transporter atp-binding protein
ISU60_12695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_12700	COG4215	(ABC) transporter
ISU60_12705	COG4160	amino acid transport
ISU60_12730	COG1120	ATPase activity
ISU60_12735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU60_12740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU60_12765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_12780	COG1177	transmembrane transport
ISU60_12785	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU60_12790	COG3842	ATPase activity
ISU60_12795	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISU60_12825	COG0671	phosphoesterase, PA-phosphatase related
ISU60_12835	COG1349	DNA-binding transcription factor activity
ISU60_12840	COG0814	amino acid
ISU60_12845	COG1686	Belongs to the peptidase S11 family
ISU60_12850	COG2011	ABC-type metal ion transport system permease component
ISU60_12875	COG0625	glutathione transferase activity
ISU60_12880	COG4771	TonB-dependent receptor
ISU60_12900	COG0833	amino acid
ISU60_12905	COG0583	DNA-binding transcription factor activity
ISU60_12910	COG2855	membrane
ISU60_12920	COG3188	usher protein
ISU60_12925	COG3121	Chaperone
ISU60_12940	COG3710	Transcriptional regulator
ISU60_12945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU60_12945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU60_12945	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ISU60_12950	COG1105	Belongs to the carbohydrate kinase PfkB family
ISU60_12960	COG0494	nUDIX hydrolase
ISU60_12970	COG1129	ABC transporter
ISU60_13010	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_13035	COG0246	Mannitol dehydrogenase
ISU60_13040	COG2186	Transcriptional regulator
ISU60_13045	COG0523	cobalamin synthesis protein
ISU60_13050	COG0671	phosphoesterase, PA-phosphatase related
ISU60_13055	COG0791	NLP P60 protein
ISU60_13060	COG2200	EAL domain
ISU60_13065	COG4166	transmembrane transport
ISU60_13070	COG4174	ABC transporter (Permease)
ISU60_13075	COG4239	(ABC) transporter, permease
ISU60_13080	COG4172	Belongs to the ABC transporter superfamily
ISU60_13090	COG2814	Major facilitator Superfamily
ISU60_13095	COG1187	pseudouridine synthase activity
ISU60_13100	COG1061	Type III restriction enzyme res subunit
ISU60_13120	COG3082	Protein of unknown function (DUF1414)
ISU60_13125	COG3083	sulfuric ester hydrolase activity
ISU60_13140	COG3157	Type VI secretion system effector, Hcp
ISU60_13160	COG2723	6-phospho-beta-galactosidase activity
ISU60_13165	COG1737	Transcriptional regulator
ISU60_13185	COG3299	homolog of phage Mu protein gp47
ISU60_13225	COG4386	tail sheath protein
ISU60_13245	COG3622	Belongs to the hyi family
ISU60_13250	COG1349	DNA-binding transcription factor activity
ISU60_13260	COG3395	kinase activity
ISU60_13300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISU60_13325	COG2223	nitrite transmembrane transporter activity
ISU60_13330	COG2198	Histidine kinase
ISU60_13330	COG0642	Histidine kinase
ISU60_13335	COG2198	Histidine kinase
ISU60_13335	COG0642	Histidine kinase
ISU60_13345	COG2205	protein histidine kinase activity
ISU60_13345	COG0784	Response regulator, receiver
ISU60_13370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU60_13385	COG0814	amino acid
ISU60_13410	COG0697	spore germination
ISU60_13420	COG1982	Orn Lys Arg decarboxylase major
ISU60_13425	COG0531	amino acid
ISU60_13430	COG1174	glycine betaine transport
ISU60_13435	COG1125	glycine betaine transport
ISU60_13440	COG1174	glycine betaine transport
ISU60_13450	COG2897	thiosulfate sulfurtransferase activity
ISU60_13470	COG1122	ATPase activity
ISU60_13490	COG4807	Protein conserved in bacteria
ISU60_13505	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ISU60_13515	COG2261	transglycosylase associated protein
ISU60_13535	COG0277	FAD linked oxidase domain protein
ISU60_13540	COG1686	Belongs to the peptidase S11 family
ISU60_13550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU60_13575	COG3328	transposase activity
ISU60_13610	COG0513	Belongs to the DEAD box helicase family
ISU60_13615	COG1309	transcriptional regulator
ISU60_13625	COG1131	(ABC) transporter
ISU60_13630	COG0842	Transport permease protein
ISU60_13635	COG0842	Transport permease protein
ISU60_13655	COG1902	pentaerythritol trinitrate reductase activity
ISU60_13685	COG0670	Belongs to the BI1 family
ISU60_13690	COG0314	molybdopterin synthase activity
ISU60_13695	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ISU60_13705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ISU60_13710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ISU60_13715	COG4628	conserved protein (DUF2132)
ISU60_13725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ISU60_13735	COG2226	methyltransferase
ISU60_13760	COG0561	phosphatase activity
ISU60_13770	COG4149	molybdate abc transporter
ISU60_13775	COG0725	ABC transporter, periplasmic molybdate-binding protein
ISU60_13785	COG3585	molybdate ion transport
ISU60_13785	COG2005	Transcriptional regulator
ISU60_13790	COG1119	ATPase activity
ISU60_13800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ISU60_13805	COG1085	galactose-1-phosphate uridylyltransferase
ISU60_13820	COG2017	converts alpha-aldose to the beta-anomer
ISU60_13835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU60_13840	COG1230	cation diffusion facilitator family transporter
ISU60_13870	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ISU60_13875	COG2885	chlorophyll binding
ISU60_13885	COG3064	Membrane
ISU60_13885	COG3064	Membrane
ISU60_13890	COG0848	biopolymer transport protein
ISU60_13895	COG0811	peptide transport
ISU60_13900	COG0824	Thioesterase
ISU60_13905	COG3790	cyd operon protein YbgE
ISU60_13910	COG4890	Cyd operon protein YbgT
ISU60_13915	COG1294	oxidase, subunit
ISU60_13920	COG1271	oxidase subunit
ISU60_13925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ISU60_13935	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU60_13950	COG1053	succinate dehydrogenase
ISU60_13955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ISU60_13960	COG2009	succinate dehydrogenase
ISU60_13975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ISU60_13980	COG0497	DNA recombination
ISU60_13985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU60_13995	COG2867	negative regulation of translational initiation
ISU60_14015	COG0582	viral genome integration into host DNA
ISU60_14065	COG3657	addiction module killer protein
ISU60_14085	COG3433	isochorismatase activity
ISU60_14085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU60_14085	COG2226	methyltransferase
ISU60_14095	COG3433	isochorismatase activity
ISU60_14095	COG2226	methyltransferase
ISU60_14095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU60_14120	COG2375	cellular response to nickel ion
ISU60_14120	COG1132	(ABC) transporter
ISU60_14125	COG1132	(ABC) transporter
ISU60_14140	COG2610	gluconate transmembrane transporter activity
ISU60_14155	COG3501	Rhs element vgr protein
ISU60_14165	COG3209	COG3209 Rhs family protein
ISU60_14180	COG0471	metal ion transport
ISU60_14200	COG2211	Major facilitator Superfamily
ISU60_14250	COG2771	luxR family
ISU60_14255	COG3916	Acyl-homoserine-lactone synthase
ISU60_14370	COG1982	Orn Lys Arg decarboxylase major
ISU60_14375	COG1879	ABC-type sugar transport system periplasmic component
ISU60_14380	COG1129	ABC transporter
ISU60_14385	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_14390	COG4774	siderophore transport
ISU60_14410	COG1194	a g-specific adenine glycosylase
ISU60_14420	COG3171	Protein conserved in bacteria
ISU60_14440	COG3064	Membrane
ISU60_14440	COG1073	alpha beta
ISU60_14440	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ISU60_14445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU60_14450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ISU60_14460	COG0762	integral membrane protein
ISU60_14465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISU60_14470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ISU60_14475	COG2805	Type II/IV secretion system protein
ISU60_14485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU60_14500	COG0189	ligase activity
ISU60_14505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ISU60_14510	COG2356	endonuclease I
ISU60_14525	COG1166	arginine decarboxylase activity
ISU60_14540	COG0501	Belongs to the peptidase M48B family
ISU60_14545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISU60_14580	COG0191	fructose-bisphosphate aldolase activity
ISU60_14615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISU60_14625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ISU60_14645	COG0006	proline dipeptidase activity
ISU60_14650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU60_14655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU60_14700	COG1272	protein, Hemolysin III
ISU60_14725	COG0745	RESPONSE REGULATOR receiver
ISU60_14730	COG2205	protein histidine kinase activity
ISU60_14735	COG4452	Inner membrane protein CreD
ISU60_14740	COG0716	FMN binding
ISU60_14745	COG4974	Belongs to the 'phage' integrase family
ISU60_14750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU60_14755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ISU60_14775	COG0582	viral genome integration into host DNA
ISU60_14800	COG2944	sequence-specific DNA binding
ISU60_14890	COG1695	Transcriptional regulator
ISU60_14895	COG0791	NLP P60 protein
ISU60_14905	COG1879	ABC-type sugar transport system periplasmic component
ISU60_14910	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_14915	COG1129	ABC transporter
ISU60_14925	COG2182	Extracellular solute-binding protein
ISU60_14930	COG1175	transmembrane transport
ISU60_14935	COG3833	ABC-type maltose transport systems, permease component
ISU60_14940	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ISU60_14945	COG1874	Beta-galactosidase
ISU60_14950	COG1263	PTS System
ISU60_14950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU60_14970	COG2271	Major facilitator Superfamily
ISU60_14995	COG3119	arylsulfatase activity
ISU60_15000	COG0641	radical SAM
ISU60_15010	COG1028	Short-chain dehydrogenase reductase Sdr
ISU60_15020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU60_15025	COG3716	PTS system mannose fructose sorbose family IID component
ISU60_15030	COG3715	PTS system
ISU60_15035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU60_15040	COG2222	sugar isomerase
ISU60_15050	COG1349	DNA-binding transcription factor activity
ISU60_15055	COG3119	arylsulfatase activity
ISU60_15085	COG1953	Uracil, thiamine, allantoin
ISU60_15105	COG2226	methyltransferase
ISU60_15110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU60_15115	COG0741	lytic transglycosylase activity
ISU60_15115	COG1388	LysM domain
ISU60_15130	COG0656	L-ascorbic acid biosynthetic process
ISU60_15160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU60_15170	COG2011	ABC-type metal ion transport system permease component
ISU60_15175	COG1464	Belongs to the NlpA lipoprotein family
ISU60_15185	COG1720	tRNA m6t6A37 methyltransferase activity
ISU60_15195	COG3015	lipoprotein NlpE involved in copper resistance
ISU60_15205	COG4681	YaeQ
ISU60_15215	COG4568	rho-dependent transcription termination
ISU60_15225	COG0037	tRNA processing
ISU60_15230	COG0346	lactoylglutathione lyase activity
ISU60_15240	COG0587	DNA-directed DNA polymerase activity
ISU60_15265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ISU60_15280	COG0750	zinc metalloprotease
ISU60_15285	COG0575	Belongs to the CDS family
ISU60_15345	COG0564	pseudouridine synthase activity
ISU60_15350	COG3098	single-species biofilm formation
ISU60_15370	COG1611	Belongs to the LOG family
ISU60_15385	COG2363	Small membrane protein
ISU60_15390	COG0583	DNA-binding transcription factor activity
ISU60_15400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISU60_15405	COG2166	iron-sulfur cluster assembly
ISU60_15410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ISU60_15415	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ISU60_15430	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU60_15440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ISU60_15445	COG1074	ATP-dependent DNA helicase activity
ISU60_15455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ISU60_15505	COG0667	Aldo Keto reductase
ISU60_15535	COG1609	Transcriptional regulator
ISU60_15545	COG0583	DNA-binding transcription factor activity
ISU60_15550	COG2814	Major facilitator Superfamily
ISU60_15555	COG0583	DNA-binding transcription factor activity
ISU60_15570	COG0840	transmembrane signaling receptor activity
ISU60_15615	COG2165	general secretion pathway protein
ISU60_15635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU60_15655	COG0288	reversible hydration of carbon dioxide
ISU60_15695	COG4771	TonB-dependent receptor
ISU60_15700	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU60_15705	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ISU60_15750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU60_15760	COG5001	Diguanylate cyclase
ISU60_15800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ISU60_15805	COG1191	sigma factor activity
ISU60_15830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ISU60_15850	COG3710	Transcriptional regulator
ISU60_15870	COG1256	bacterial-type flagellum assembly
ISU60_15880	COG1706	bacterial-type flagellum-dependent cell motility
ISU60_15890	COG4786	Flagellar basal body rod
ISU60_15895	COG4787	bacterial-type flagellum-dependent cell motility
ISU60_15900	COG1749	Flagellar hook protein flgE
ISU60_15905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ISU60_15910	COG1558	bacterial-type flagellum-dependent cell motility
ISU60_15915	COG1815	bacterial-type flagellum-dependent cell motility
ISU60_15920	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ISU60_15960	COG1677	Flagellar hook-basal body complex protein FliE
ISU60_15985	COG1987	bacterial-type flagellum assembly
ISU60_15990	COG1684	flagellar biosynthetic protein fliR
ISU60_15995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU60_16015	COG4592	Periplasmic binding protein
ISU60_16050	COG4964	Belongs to the GSP D family
ISU60_16055	COG4964	Belongs to the GSP D family
ISU60_16105	COG0848	biopolymer transport protein
ISU60_16110	COG0811	peptide transport
ISU60_16115	COG0626	cystathionine gamma-synthase activity
ISU60_16120	COG0586	Pfam SNARE associated Golgi protein
ISU60_16125	COG2207	Transcriptional regulator
ISU60_16130	COG1979	alcohol dehydrogenase
ISU60_16140	COG0656	L-ascorbic acid biosynthetic process
ISU60_16150	COG2132	Multicopper oxidase
ISU60_16160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ISU60_16170	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISU60_16175	COG0583	DNA-binding transcription factor activity
ISU60_16185	COG3150	esterase
ISU60_16190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ISU60_16195	COG3151	Protein conserved in bacteria
ISU60_16200	COG0494	nUDIX hydrolase
ISU60_16205	COG1538	Outer membrane efflux protein
ISU60_16215	COG0754	glutathionylspermidine amidase activity
ISU60_16220	COG3384	dioxygenase
ISU60_16240	COG0531	amino acid
ISU60_16255	COG3025	triphosphatase activity
ISU60_16260	COG4991	sh3 domain protein
ISU60_16275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISU60_16290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ISU60_16295	COG0358	DNA primase activity
ISU60_16365	COG0251	oxidation-reduction process
ISU60_16385	COG0436	Aminotransferase
ISU60_16405	COG1289	transmembrane transporter activity
ISU60_16425	COG0395	ABC-type sugar transport system, permease component
ISU60_16435	COG2182	Extracellular solute-binding protein
ISU60_16440	COG1609	Transcriptional regulator
ISU60_16445	COG3459	Glycosyltransferase 36 associated
ISU60_16450	COG3842	ATPase activity
ISU60_16470	COG3210	domain, Protein
ISU60_16475	COG3210	domain, Protein
ISU60_16505	COG3210	domain, Protein
ISU60_16510	COG2831	hemolysin activation secretion protein
ISU60_16515	COG4245	von Willebrand factor, type A
ISU60_16530	COG4245	von Willebrand factor, type A
ISU60_16545	COG3247	response to pH
ISU60_16550	COG1902	pentaerythritol trinitrate reductase activity
ISU60_16550	COG0446	pyridine nucleotide-disulphide oxidoreductase
ISU60_16565	COG1451	nucleotide metabolic process
ISU60_16570	COG0673	inositol 2-dehydrogenase activity
ISU60_16590	COG2721	sulfolactate sulfo-lyase activity
ISU60_16610	COG2271	Major facilitator Superfamily
ISU60_16625	COG0586	Pfam SNARE associated Golgi protein
ISU60_16640	COG4575	ribosome binding
ISU60_16645	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ISU60_16655	COG2259	Doxx family
ISU60_16675	COG0494	nUDIX hydrolase
ISU60_16705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ISU60_16710	COG0849	cell division
ISU60_16715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ISU60_16735	COG0772	Belongs to the SEDS family
ISU60_16750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ISU60_16755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ISU60_16760	COG0768	penicillin binding
ISU60_16765	COG3116	cell division
ISU60_16790	COG1609	Transcriptional regulator
ISU60_16805	COG0028	Belongs to the TPP enzyme family
ISU60_16810	COG1022	Amp-dependent synthetase and ligase
ISU60_16835	COG0473	3-isopropylmalate dehydrogenase activity
ISU60_16850	COG2814	Major facilitator Superfamily
ISU60_16860	COG4143	(ABC) transporter
ISU60_16865	COG1178	ABC-type Fe3 transport system permease component
ISU60_16870	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ISU60_16875	COG0586	Pfam SNARE associated Golgi protein
ISU60_16880	COG0417	DNA replication proofreading
ISU60_16900	COG3047	cAMP biosynthetic process
ISU60_16900	COG2885	chlorophyll binding
ISU60_16995	COG0564	pseudouridine synthase activity
ISU60_17000	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ISU60_17050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ISU60_17060	COG2966	Psort location CytoplasmicMembrane, score
ISU60_17065	COG1280	lysine exporter protein (LysE YggA)
ISU60_17070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISU60_17095	COG1047	Peptidyl-prolyl cis-trans
ISU60_17110	COG0196	riboflavin kinase activity
ISU60_17120	COG0583	DNA-binding transcription factor activity
ISU60_17140	COG1584	GPR1 FUN34 yaaH family protein
ISU60_17155	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISU60_17200	COG0745	RESPONSE REGULATOR receiver
ISU60_17205	COG3045	CreA protein
ISU60_17210	COG2207	Transcriptional regulator
ISU60_17210	COG3708	Transcriptional regulator
ISU60_17225	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ISU60_17230	COG0741	lytic transglycosylase activity
ISU60_17245	COG2199	diguanylate cyclase activity
ISU60_17250	COG2885	chlorophyll binding
ISU60_17275	COG0560	Phosphoserine phosphatase
ISU60_17280	COG3726	membrane protein affecting hemolysin expression
ISU60_17305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU60_17310	COG0084	hydrolase, TatD family'
ISU60_17315	COG4667	esterase of the alpha-beta hydrolase superfamily
ISU60_17325	COG2823	Periplasmic or secreted lipoprotein
ISU60_17335	COG0456	acetyltransferase
ISU60_17340	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ISU60_17380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU60_17385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU60_17400	COG0859	PFAM glycosyl transferase family 9
ISU60_17405	COG1070	Carbohydrate kinase
ISU60_17455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU60_17455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU60_17455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU60_17460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU60_17465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU60_17470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU60_17475	COG2207	Transcriptional regulator
ISU60_17485	COG4269	membrane
ISU60_17540	COG1401	restriction endodeoxyribonuclease activity
ISU60_17565	COG0582	viral genome integration into host DNA
ISU60_17575	COG0795	lipopolysaccharide-transporting ATPase activity
ISU60_17580	COG0795	lipopolysaccharide-transporting ATPase activity
ISU60_17590	COG2927	DNA polymerase III (CHI subunit)
ISU60_17595	COG0525	valine-tRNA ligase activity
ISU60_17605	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ISU60_17615	COG2731	YhcH YjgK YiaL family protein
ISU60_17625	COG0601	transmembrane transport
ISU60_17630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU60_17635	COG0444	Belongs to the ABC transporter superfamily
ISU60_17640	COG4608	Belongs to the ABC transporter superfamily
ISU60_17655	COG2188	Transcriptional regulator
ISU60_17660	COG3624	Phosphonate C-P lyase system protein PhnG
ISU60_17665	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ISU60_17670	COG3626	phosphonate metabolism
ISU60_17675	COG3627	carbon phosphorus lyase activity
ISU60_17680	COG4107	phosphonate C-P lyase system protein PhnK
ISU60_17685	COG4778	phosphonate C-P lyase system protein PhnL
ISU60_17690	COG3454	Phosphonate metabolism
ISU60_17695	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ISU60_17700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ISU60_17705	COG0702	epimerase
ISU60_17720	COG3842	ATPase activity
ISU60_17725	COG0395	ABC-type sugar transport system, permease component
ISU60_17730	COG1175	transmembrane transport
ISU60_17735	COG1653	transport
ISU60_17755	COG3153	acetyltransferase
ISU60_17760	COG3154	lipid carrier protein
ISU60_17765	COG0826	peptidase U32
ISU60_17770	COG0826	peptidase U32
ISU60_17780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU60_17790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISU60_17810	COG0513	Belongs to the DEAD box helicase family
ISU60_17855	COG0195	Participates in both transcription termination and antitermination
ISU60_17875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ISU60_17885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ISU60_17900	COG1534	Rna-binding protein
ISU60_17910	COG2027	D-alanyl-D-alanine carboxypeptidase
ISU60_17915	COG0745	RESPONSE REGULATOR receiver
ISU60_17920	COG0642	Histidine kinase
ISU60_17930	COG0697	spore germination
ISU60_17945	COG0142	geranyltranstransferase activity
ISU60_17955	COG3423	Transcriptional regulator
ISU60_17975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ISU60_17980	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ISU60_17985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ISU60_17990	COG2105	PFAM AIG2 family protein
ISU60_17995	COG2911	Protein conserved in bacteria
ISU60_18000	COG0729	surface antigen
ISU60_18010	COG1253	flavin adenine dinucleotide binding
ISU60_18020	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ISU60_18030	COG0737	Belongs to the 5'-nucleotidase family
ISU60_18040	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU60_18045	COG3061	Opacity-associated protein A
ISU60_18065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ISU60_18075	COG0360	Binds together with S18 to 16S ribosomal RNA
ISU60_18080	COG1073	alpha beta
ISU60_18100	COG3650	response to hydrogen peroxide
ISU60_18105	COG1960	acyl-CoA dehydrogenase activity
ISU60_18110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU60_18115	COG0557	exoribonuclease II activity
ISU60_18130	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ISU60_18135	COG0330	HflC and HflK could
ISU60_18140	COG0330	HflC and HflK could
ISU60_18145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ISU60_18165	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU60_18170	COG0802	atpase or kinase
ISU60_18175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ISU60_18175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ISU60_18180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ISU60_18195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ISU60_18210	COG1511	domain protein
ISU60_18210	COG3264	Mechanosensitive ion channel
ISU60_18225	COG1053	succinate dehydrogenase
ISU60_18230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISU60_18240	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ISU60_18285	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISU60_18300	COG3383	formate dehydrogenase (NAD+) activity
ISU60_18305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU60_18310	COG0493	'glutamate synthase
ISU60_18310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU60_18315	COG1309	transcriptional regulator
ISU60_18375	COG1454	alcohol dehydrogenase
ISU60_18385	COG0629	single-stranded DNA binding
ISU60_18390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ISU60_18395	COG2315	Protein conserved in bacteria
ISU60_18400	COG1448	Aminotransferase
ISU60_18425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU60_18430	COG0735	belongs to the Fur family
ISU60_18440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ISU60_18480	COG3121	Chaperone
ISU60_18540	COG1358	cellular component organization or biogenesis
ISU60_18565	COG3721	Heme iron utilization protein
ISU60_18570	COG0702	epimerase
ISU60_18580	COG4771	TonB-dependent receptor
ISU60_18585	COG3720	iron ion transport
ISU60_18590	COG4558	Periplasmic binding protein
ISU60_18595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU60_18605	COG0626	cystathionine gamma-synthase activity
ISU60_18610	COG0814	amino acid
ISU60_18615	COG0583	DNA-binding transcription factor activity
ISU60_18620	COG0425	Belongs to the sulfur carrier protein TusA family
ISU60_18625	COG2391	methyltransferase activity
ISU60_18735	COG1301	dicarboxylic acid transport
ISU60_18745	COG3162	membrane
ISU60_18805	COG0151	Belongs to the GarS family
ISU60_18825	COG1515	deoxyribonuclease V activity
ISU60_18860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISU60_18915	COG0250	Participates in transcription elongation, termination and antitermination
ISU60_18975	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ISU60_19005	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ISU60_19010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ISU60_19025	COG1739	Uncharacterized protein family UPF0029
ISU60_19050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISU60_19085	COG0805	protein transport
ISU60_19095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU60_19115	COG1322	Protein conserved in bacteria
ISU60_19120	COG0586	Pfam SNARE associated Golgi protein
ISU60_19125	COG1966	Carbon starvation protein
ISU60_19140	COG0412	Dienelactone hydrolase
ISU60_19150	COG0583	DNA-binding transcription factor activity
ISU60_19155	COG0697	spore germination
ISU60_19160	COG0679	Auxin Efflux Carrier
ISU60_19225	COG0410	ABC transporter
ISU60_19235	COG4177	L-phenylalanine transmembrane transporter activity
ISU60_19245	COG0683	leucine binding
ISU60_19265	COG2177	Part of the ABC transporter FtsEX involved in
ISU60_19270	COG2884	Cell division ATP-binding protein ftsE
ISU60_19275	COG0552	protein localization to endoplasmic reticulum
ISU60_19275	COG0552	protein localization to endoplasmic reticulum
ISU60_19280	COG0742	ribosomal rna small subunit methyltransferase
ISU60_19285	COG3776	membrane
ISU60_19300	COG3714	YhhN family
ISU60_19315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ISU60_19325	COG0247	lactate metabolic process
ISU60_19335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU60_19340	COG0584	glycerophosphoryl diester phosphodiesterase
ISU60_19350	COG0561	phosphatase activity
ISU60_19355	COG2267	carboxylic ester hydrolase activity
ISU60_19360	COG1280	lysine exporter protein (LysE YggA)
ISU60_19365	COG1280	lysine exporter protein (LysE YggA)
ISU60_19370	COG0514	ATP-dependent DNA helicase (RecQ)
ISU60_19375	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ISU60_19380	COG2050	protein possibly involved in aromatic compounds catabolism
ISU60_19395	COG5564	TIM-barrel signal transduction protein
ISU60_19400	COG5441	Belongs to the UPF0261 family
ISU60_19410	COG0210	DNA helicase
ISU60_19415	COG1011	Hydrolase
ISU60_19420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ISU60_19425	COG3159	Protein conserved in bacteria
ISU60_19445	COG3072	Adenylate cyclase
ISU60_19460	COG1587	Uroporphyrinogen-III synthase
ISU60_19465	COG2959	enzyme of heme biosynthesis
ISU60_19470	COG3071	HemY protein
ISU60_19500	COG1113	amino acid transport
ISU60_19520	COG2244	polysaccharide biosynthetic process
ISU60_19525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ISU60_19530	COG0456	acetyltransferase
ISU60_19535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ISU60_19540	COG1088	dTDP-glucose 4,6-dehydratase activity
ISU60_19545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ISU60_19550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ISU60_19555	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU60_19560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ISU60_19565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ISU60_19570	COG3118	belongs to the thioredoxin family
ISU60_19595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU60_19605	COG3328	transposase activity
ISU60_19615	COG3121	Chaperone
ISU60_19630	COG3121	Chaperone
ISU60_19665	COG0583	DNA-binding transcription factor activity
ISU60_19710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU60_19715	COG3978	acetolactate synthase activity
ISU60_19735	COG3085	chromosome segregation
ISU60_19745	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_19750	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU60_19755	COG1129	ABC transporter
ISU60_19760	COG1879	ABC-type sugar transport system periplasmic component
ISU60_19830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU60_19830	COG0678	peroxiredoxin activity
ISU60_19835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU60_19860	COG1629	transport
ISU60_19875	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ISU60_19900	COG0527	aspartate kinase activity
ISU60_19900	COG0460	homoserine dehydrogenase
ISU60_19915	COG4682	membrane
ISU60_19925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ISU60_19930	COG1609	Transcriptional regulator
ISU60_19935	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU60_19950	COG1575	Belongs to the MenA family. Type 1 subfamily
ISU60_19990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ISU60_19995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU60_20000	COG1494	fructose-1,6-bisphosphatase
ISU60_20010	COG3152	Membrane
ISU60_20025	COG0583	DNA-binding transcription factor activity
ISU60_20030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ISU60_20035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISU60_20040	COG0471	metal ion transport
ISU60_20050	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ISU60_20075	COG3678	ATP-independent chaperone mediated protein folding
ISU60_20080	COG0745	RESPONSE REGULATOR receiver
ISU60_20085	COG2205	protein histidine kinase activity
ISU60_20090	COG2169	Transcriptional regulator
ISU60_20090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU60_20095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ISU60_20100	COG1045	serine acetyltransferase
ISU60_20115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU60_20120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISU60_20130	COG4942	peptidase
ISU60_20145	COG0156	8-amino-7-oxononanoate synthase activity
ISU60_20155	COG0859	PFAM glycosyl transferase family 9
ISU60_20160	COG0859	PFAM glycosyl transferase family 9
ISU60_20165	COG1519	Transferase
ISU60_20200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ISU60_20225	COG1561	YicC-like family, N-terminal region
ISU60_20230	COG2860	membrane
ISU60_20250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU60_20255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU60_20260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ISU60_20270	COG0786	glutamate:sodium symporter activity
ISU60_20275	COG2233	PERMEase
ISU60_20280	COG2982	Protein involved in outer membrane biogenesis
ISU60_20285	COG0456	acetyltransferase
ISU60_20310	COG1011	Hydrolase
ISU60_20320	COG0174	glutamine synthetase
ISU60_20325	COG3852	Histidine kinase
ISU60_20335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU60_20355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU60_20355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU60_20360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU60_20365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ISU60_20370	COG3084	Protein conserved in bacteria
ISU60_20380	COG1763	Mo-molybdopterin cofactor biosynthetic process
ISU60_20385	COG3328	transposase activity
ISU60_20410	COG2186	Transcriptional regulator
ISU60_20415	COG0477	Major facilitator Superfamily
ISU60_20430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU60_20460	COG1522	sequence-specific DNA binding
ISU60_20465	COG0716	FMN binding
ISU60_20480	COG3312	ion transport
ISU60_20535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ISU60_20540	COG0573	inorganic phosphate transmembrane transporter activity
ISU60_20545	COG0581	inorganic phosphate transmembrane transporter activity
ISU60_20555	COG0704	Plays a role in the regulation of phosphate uptake
ISU60_20565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU60_20570	COG0765	amino acid transport
ISU60_20575	COG0765	amino acid transport
ISU60_20580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU60_20590	COG2252	PERMEase
ISU60_20620	COG0706	membrane insertase activity
ISU60_20635	COG0230	Belongs to the bacterial ribosomal protein bL34 family