locus-tag	class	description
CH63_10	COG1737	Transcriptional regulator
CH63_1001	COG1953	Uracil, thiamine, allantoin
CH63_1003	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH63_1005	COG2226	methyltransferase
CH63_1007	COG0741	lytic transglycosylase activity
CH63_1007	COG1388	LysM domain
CH63_101	COG3139	Protein of unknown function (DUF1315)
CH63_1010	COG0656	L-ascorbic acid biosynthetic process
CH63_1016	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH63_1018	COG2011	ABC-type metal ion transport system permease component
CH63_1019	COG1464	Belongs to the NlpA lipoprotein family
CH63_102	COG1335	isochorismatase
CH63_1021	COG1720	tRNA m6t6A37 methyltransferase activity
CH63_1023	COG3015	lipoprotein NlpE involved in copper resistance
CH63_1025	COG4681	YaeQ
CH63_1027	COG4568	rho-dependent transcription termination
CH63_1029	COG0037	tRNA processing
CH63_103	COG0252	asparaginase activity
CH63_1030	COG0346	lactoylglutathione lyase activity
CH63_1032	COG0587	DNA-directed DNA polymerase activity
CH63_1034	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH63_1038	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH63_104	COG0616	signal peptide processing
CH63_1040	COG0750	zinc metalloprotease
CH63_1041	COG0575	Belongs to the CDS family
CH63_1042	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH63_1048	COG0024	Methionine aminopeptidase
CH63_105	COG0778	Nitroreductase
CH63_1051	COG1943	Transposase
CH63_1054	COG0564	pseudouridine synthase activity
CH63_1055	COG3098	single-species biofilm formation
CH63_1056	COG1943	Transposase
CH63_1059	COG1611	Belongs to the LOG family
CH63_106	COG0709	Synthesizes selenophosphate from selenide and ATP
CH63_1060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH63_1062	COG2363	Small membrane protein
CH63_1063	COG0583	DNA-binding transcription factor activity
CH63_1065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH63_1066	COG2166	iron-sulfur cluster assembly
CH63_1067	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH63_1068	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH63_107	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH63_1071	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH63_1073	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH63_1074	COG1074	ATP-dependent DNA helicase activity
CH63_1076	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH63_1088	COG0667	Aldo Keto reductase
CH63_109	COG0494	nUDIX hydrolase
CH63_1095	COG0019	diaminopimelate decarboxylase activity
CH63_1096	COG1609	Transcriptional regulator
CH63_1097	COG2814	Major facilitator Superfamily
CH63_1098	COG0583	DNA-binding transcription factor activity
CH63_1099	COG0583	DNA-binding transcription factor activity
CH63_11	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH63_110	COG0708	Exodeoxyribonuclease III
CH63_111	COG0583	DNA-binding transcription factor activity
CH63_1121	COG0288	reversible hydration of carbon dioxide
CH63_1129	COG3119	arylsulfatase activity
CH63_1130	COG1349	DNA-binding transcription factor activity
CH63_1132	COG2222	sugar isomerase
CH63_1133	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_1134	COG3715	PTS system
CH63_1135	COG3716	PTS system mannose fructose sorbose family IID component
CH63_1136	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_1138	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_1139	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_114	COG0788	formyltetrahydrofolate deformylase activity
CH63_1141	COG0641	radical SAM
CH63_1142	COG3119	arylsulfatase activity
CH63_1144	COG0191	fructose-bisphosphate aldolase activity
CH63_1148	COG2271	Major facilitator Superfamily
CH63_115	COG3328	transposase activity
CH63_1152	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_1152	COG1263	PTS System
CH63_1153	COG1874	Beta-galactosidase
CH63_1154	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH63_1155	COG3833	ABC-type maltose transport systems, permease component
CH63_1156	COG1175	transmembrane transport
CH63_1157	COG2182	Extracellular solute-binding protein
CH63_1159	COG1129	ABC transporter
CH63_1160	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_1161	COG1879	ABC-type sugar transport system periplasmic component
CH63_1163	COG0791	NLP P60 protein
CH63_1164	COG1695	Transcriptional regulator
CH63_117	COG0745	RESPONSE REGULATOR receiver
CH63_1181	COG2944	sequence-specific DNA binding
CH63_1186	COG0582	viral genome integration into host DNA
CH63_1190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH63_1191	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH63_1192	COG4974	Belongs to the 'phage' integrase family
CH63_1193	COG0716	FMN binding
CH63_1194	COG4452	Inner membrane protein CreD
CH63_1195	COG2205	protein histidine kinase activity
CH63_1196	COG0745	RESPONSE REGULATOR receiver
CH63_1197	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH63_120	COG1435	thymidine kinase activity
CH63_1200	COG1272	protein, Hemolysin III
CH63_1202	COG5295	Hep Hag repeat protein
CH63_1208	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH63_1209	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH63_1210	COG0006	proline dipeptidase activity
CH63_1213	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH63_1214	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH63_1215	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH63_1220	COG0191	fructose-bisphosphate aldolase activity
CH63_1224	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH63_1225	COG0501	Belongs to the peptidase M48B family
CH63_1227	COG1166	arginine decarboxylase activity
CH63_1231	COG2356	endonuclease I
CH63_1232	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH63_1233	COG0189	ligase activity
CH63_1236	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH63_1238	COG2805	Type II/IV secretion system protein
CH63_1239	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH63_1240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH63_1241	COG0762	integral membrane protein
CH63_1243	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH63_1244	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH63_1245	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH63_1245	COG1073	alpha beta
CH63_1245	COG3064	Membrane
CH63_1248	COG2066	Belongs to the glutaminase family
CH63_1249	COG3171	Protein conserved in bacteria
CH63_1251	COG1194	a g-specific adenine glycosylase
CH63_1255	COG4774	siderophore transport
CH63_1256	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_1257	COG1129	ABC transporter
CH63_1258	COG1879	ABC-type sugar transport system periplasmic component
CH63_1259	COG1982	Orn Lys Arg decarboxylase major
CH63_1263	COG1662	PFAM IS1 transposase
CH63_127	COG3121	Chaperone
CH63_1285	COG2771	luxR family
CH63_1286	COG3916	Acyl-homoserine-lactone synthase
CH63_1296	COG2211	Major facilitator Superfamily
CH63_1299	COG2801	Transposase and inactivated derivatives
CH63_13	COG0800	Aldolase
CH63_1301	COG0471	metal ion transport
CH63_1304	COG3209	COG3209 Rhs family protein
CH63_1306	COG3501	Rhs element vgr protein
CH63_1311	COG2610	gluconate transmembrane transporter activity
CH63_1315	COG1132	(ABC) transporter
CH63_1322	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH63_1322	COG2226	methyltransferase
CH63_1322	COG3433	isochorismatase activity
CH63_1323	COG3433	isochorismatase activity
CH63_1323	COG2226	methyltransferase
CH63_1323	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH63_1326	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH63_1326	COG2226	methyltransferase
CH63_1326	COG3433	isochorismatase activity
CH63_133	COG2995	paraquat-inducible protein a
CH63_1331	COG3162	membrane
CH63_1333	COG1301	dicarboxylic acid transport
CH63_134	COG1956	GAF domain-containing protein
CH63_1355	COG2391	methyltransferase activity
CH63_1356	COG0425	Belongs to the sulfur carrier protein TusA family
CH63_1357	COG0583	DNA-binding transcription factor activity
CH63_1358	COG0814	amino acid
CH63_1359	COG0626	cystathionine gamma-synthase activity
CH63_136	COG0793	Belongs to the peptidase S41A family
CH63_1361	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_1362	COG4558	Periplasmic binding protein
CH63_1363	COG3720	iron ion transport
CH63_1364	COG4771	TonB-dependent receptor
CH63_1365	COG0702	epimerase
CH63_1366	COG3721	Heme iron utilization protein
CH63_1371	COG1358	cellular component organization or biogenesis
CH63_1383	COG3121	Chaperone
CH63_139	COG3539	Fimbrial protein
CH63_1391	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH63_1393	COG0735	belongs to the Fur family
CH63_1394	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH63_1397	COG0305	Participates in initiation and elongation during chromosome replication
CH63_1398	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH63_1399	COG1448	Aminotransferase
CH63_140	COG3121	Chaperone
CH63_1400	COG2315	Protein conserved in bacteria
CH63_1401	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH63_1402	COG0629	single-stranded DNA binding
CH63_1404	COG1454	alcohol dehydrogenase
CH63_1417	COG1309	transcriptional regulator
CH63_1418	COG0493	'glutamate synthase
CH63_1418	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_1419	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_1420	COG3383	formate dehydrogenase (NAD+) activity
CH63_1421	COG3383	formate dehydrogenase (NAD+) activity
CH63_1424	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_143	COG3121	Chaperone
CH63_1432	COG2076	Multidrug Resistance protein
CH63_1433	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH63_1435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH63_1436	COG1053	succinate dehydrogenase
CH63_1438	COG1511	domain protein
CH63_1438	COG3264	Mechanosensitive ion channel
CH63_144	COG2814	Major facilitator Superfamily
CH63_1441	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH63_1445	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH63_1446	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH63_1446	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH63_1447	COG0802	atpase or kinase
CH63_1448	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH63_145	COG0823	Involved in the tonB-independent uptake of proteins
CH63_1452	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH63_1453	COG0330	HflC and HflK could
CH63_1454	COG0330	HflC and HflK could
CH63_1455	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH63_1458	COG0557	exoribonuclease II activity
CH63_1459	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH63_1460	COG1960	acyl-CoA dehydrogenase activity
CH63_1461	COG3650	response to hydrogen peroxide
CH63_1465	COG1073	alpha beta
CH63_1467	COG0360	Binds together with S18 to 16S ribosomal RNA
CH63_1468	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH63_147	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH63_1470	COG1943	Transposase
CH63_1472	COG3061	Opacity-associated protein A
CH63_1473	COG0545	Peptidyl-prolyl cis-trans isomerase
CH63_1475	COG0737	Belongs to the 5'-nucleotidase family
CH63_1477	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH63_1479	COG1253	flavin adenine dinucleotide binding
CH63_1481	COG0729	surface antigen
CH63_1484	COG2105	PFAM AIG2 family protein
CH63_1485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH63_1487	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH63_149	COG1988	membrane-bound metal-dependent
CH63_1491	COG3423	Transcriptional regulator
CH63_1493	COG0142	geranyltranstransferase activity
CH63_1496	COG0697	spore germination
CH63_1498	COG0642	Histidine kinase
CH63_1499	COG0745	RESPONSE REGULATOR receiver
CH63_150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH63_1500	COG2027	D-alanyl-D-alanine carboxypeptidase
CH63_1501	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH63_1502	COG1534	Rna-binding protein
CH63_1504	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH63_1505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH63_1507	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH63_151	COG1653	transport
CH63_1511	COG0195	Participates in both transcription termination and antitermination
CH63_1517	COG2801	Transposase and inactivated derivatives
CH63_1518	COG3300	MHYT domain
CH63_1518	COG5001	Diguanylate cyclase
CH63_152	COG3842	ATPase activity
CH63_1520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_1528	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH63_1529	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH63_153	COG0395	ABC-type sugar transport system, permease component
CH63_1530	COG4771	TonB-dependent receptor
CH63_1535	COG2801	Transposase and inactivated derivatives
CH63_154	COG1175	transmembrane transport
CH63_1544	COG0151	Belongs to the GarS family
CH63_1547	COG3068	Protein conserved in bacteria
CH63_1548	COG1515	deoxyribonuclease V activity
CH63_1553	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH63_1555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH63_1559	COG1943	Transposase
CH63_156	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_1567	COG0250	Participates in transcription elongation, termination and antitermination
CH63_1568	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH63_1579	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH63_158	COG1917	Cupin 2, conserved barrel domain protein
CH63_1585	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH63_1586	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH63_1587	COG1739	Uncharacterized protein family UPF0029
CH63_1589	COG1739	Uncharacterized protein family UPF0029
CH63_159	COG3328	transposase activity
CH63_16	COG0251	oxidation-reduction process
CH63_160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_1601	COG0805	protein transport
CH63_1603	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH63_1607	COG1322	Protein conserved in bacteria
CH63_1608	COG0586	Pfam SNARE associated Golgi protein
CH63_1609	COG1966	Carbon starvation protein
CH63_1611	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CH63_1612	COG0412	Dienelactone hydrolase
CH63_1615	COG0583	DNA-binding transcription factor activity
CH63_1616	COG0679	Auxin Efflux Carrier
CH63_1617	COG0584	glycerophosphoryl diester phosphodiesterase
CH63_1629	COG0410	ABC transporter
CH63_163	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH63_1630	COG0411	ABC transporter
CH63_1631	COG4177	L-phenylalanine transmembrane transporter activity
CH63_1632	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH63_1633	COG0683	leucine binding
CH63_1635	COG1943	Transposase
CH63_1637	COG2177	Part of the ABC transporter FtsEX involved in
CH63_1638	COG2884	Cell division ATP-binding protein ftsE
CH63_1639	COG0552	protein localization to endoplasmic reticulum
CH63_1639	COG0552	protein localization to endoplasmic reticulum
CH63_164	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH63_1640	COG0742	ribosomal rna small subunit methyltransferase
CH63_1641	COG3776	membrane
CH63_1644	COG3714	YhhN family
CH63_1648	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH63_165	COG1121	(ABC) transporter
CH63_1650	COG0247	lactate metabolic process
CH63_1652	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH63_1653	COG0584	glycerophosphoryl diester phosphodiesterase
CH63_1655	COG0561	phosphatase activity
CH63_1656	COG2267	carboxylic ester hydrolase activity
CH63_1657	COG1280	lysine exporter protein (LysE YggA)
CH63_1658	COG1280	lysine exporter protein (LysE YggA)
CH63_1659	COG0514	ATP-dependent DNA helicase (RecQ)
CH63_166	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH63_1660	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH63_1661	COG2050	protein possibly involved in aromatic compounds catabolism
CH63_1663	COG0598	Magnesium transport protein CorA
CH63_1664	COG5564	TIM-barrel signal transduction protein
CH63_1665	COG5441	Belongs to the UPF0261 family
CH63_1667	COG0210	DNA helicase
CH63_1668	COG1011	Hydrolase
CH63_1669	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH63_1670	COG3159	Protein conserved in bacteria
CH63_1672	COG5567	small periplasmic lipoprotein
CH63_1674	COG3072	Adenylate cyclase
CH63_1676	COG1587	Uroporphyrinogen-III synthase
CH63_1677	COG2959	enzyme of heme biosynthesis
CH63_1678	COG3071	HemY protein
CH63_1685	COG1113	amino acid transport
CH63_1689	COG2244	polysaccharide biosynthetic process
CH63_1690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH63_1691	COG0456	acetyltransferase
CH63_1692	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH63_1693	COG1088	dTDP-glucose 4,6-dehydratase activity
CH63_1694	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH63_1695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH63_1696	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH63_1697	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH63_1698	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH63_1699	COG3118	belongs to the thioredoxin family
CH63_17	COG1199	ATP-dependent helicase activity
CH63_170	COG4249	Peptidase C14 caspase catalytic subunit p20
CH63_1704	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH63_1706	COG3328	transposase activity
CH63_1708	COG3121	Chaperone
CH63_1711	COG3121	Chaperone
CH63_1718	COG0583	DNA-binding transcription factor activity
CH63_1727	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH63_1728	COG3978	acetolactate synthase activity
CH63_1731	COG3085	chromosome segregation
CH63_1732	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_1734	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_1735	COG1129	ABC transporter
CH63_1736	COG1879	ABC-type sugar transport system periplasmic component
CH63_175	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH63_1750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH63_1750	COG0678	peroxiredoxin activity
CH63_1751	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH63_176	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH63_176	COG0072	phenylalanine-tRNA ligase activity
CH63_1761	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH63_1765	COG2801	Transposase and inactivated derivatives
CH63_1767	COG0527	aspartate kinase activity
CH63_1767	COG0460	homoserine dehydrogenase
CH63_1768	COG0626	cystathionine gamma-synthase activity
CH63_1769	COG0626	cystathionine gamma-synthase activity
CH63_177	COG0776	regulation of translation
CH63_1771	COG4682	membrane
CH63_1773	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH63_1775	COG1609	Transcriptional regulator
CH63_1776	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH63_1779	COG1575	Belongs to the MenA family. Type 1 subfamily
CH63_1789	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH63_1790	COG1494	fructose-1,6-bisphosphatase
CH63_1792	COG3152	Membrane
CH63_1795	COG0583	DNA-binding transcription factor activity
CH63_1796	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH63_1797	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH63_1798	COG0471	metal ion transport
CH63_180	COG0386	Belongs to the glutathione peroxidase family
CH63_1800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH63_1805	COG3678	ATP-independent chaperone mediated protein folding
CH63_1806	COG0745	RESPONSE REGULATOR receiver
CH63_1807	COG2205	protein histidine kinase activity
CH63_1808	COG2169	Transcriptional regulator
CH63_1808	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH63_1809	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH63_181	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CH63_1810	COG1045	serine acetyltransferase
CH63_1813	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH63_1814	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH63_1816	COG4942	peptidase
CH63_1817	COG2861	carbohydrate metabolic process
CH63_1818	COG2861	carbohydrate metabolic process
CH63_1820	COG0156	8-amino-7-oxononanoate synthase activity
CH63_1822	COG0859	PFAM glycosyl transferase family 9
CH63_1823	COG0859	PFAM glycosyl transferase family 9
CH63_1824	COG1519	Transferase
CH63_1828	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH63_1831	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH63_1836	COG1561	YicC-like family, N-terminal region
CH63_1837	COG2860	membrane
CH63_1838	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH63_1841	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH63_1842	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH63_1843	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH63_1844	COG0786	glutamate:sodium symporter activity
CH63_1845	COG2233	PERMEase
CH63_1846	COG2982	Protein involved in outer membrane biogenesis
CH63_1847	COG0456	acetyltransferase
CH63_1851	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH63_1854	COG0551	DNA topoisomerase type I activity
CH63_1856	COG0758	DNA mediated transformation
CH63_1860	COG0569	domain protein
CH63_1862	COG3036	rescue of stalled ribosome
CH63_1863	COG0789	Transcriptional regulator
CH63_1866	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH63_1869	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH63_1870	COG0201	protein transport
CH63_1872	COG1841	ribosomal large subunit assembly
CH63_1880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH63_1881	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH63_1883	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH63_1884	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH63_1886	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH63_189	COG0791	NLP P60 protein
CH63_1891	COG0051	transcription antitermination factor activity, RNA binding
CH63_1894	COG1943	Transposase
CH63_1897	COG0049	tRNA binding
CH63_1898	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH63_19	COG3065	identical protein binding
CH63_1902	COG2964	Protein conserved in bacteria
CH63_1903	COG0545	Peptidyl-prolyl cis-trans isomerase
CH63_1905	COG1047	Peptidyl-prolyl cis-trans
CH63_1906	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH63_1909	COG0488	(ABC) transporter
CH63_1910	COG0488	(ABC) transporter
CH63_1911	COG1216	Glycosyl transferase, family 2
CH63_1913	COG2175	clavaminate synthase activity
CH63_1914	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH63_1916	COG4521	taurine ABC transporter
CH63_1918	COG0429	hydrolase of the alpha beta-hydrolase fold
CH63_1920	COG3954	Phosphoribulokinase
CH63_1922	COG1765	OsmC-like protein
CH63_1924	COG1289	transmembrane transporter activity
CH63_1927	COG0433	COG0433 Predicted ATPase
CH63_1928	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH63_1929	COG1486	melibiose metabolic process
CH63_1933	COG0402	S-adenosylhomocysteine deaminase activity
CH63_1934	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH63_1935	COG2146	nitrite reductase [NAD(P)H] activity
CH63_1938	COG0180	Tryptophanyl-tRNA synthetase
CH63_1939	COG0546	phosphoglycolate phosphatase activity
CH63_1940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH63_1945	COG4796	Type ii and iii secretion system protein
CH63_195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH63_195	COG0574	Belongs to the PEP-utilizing enzyme family
CH63_1950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH63_1951	COG0494	nUDIX hydrolase
CH63_1954	COG1011	Hydrolase
CH63_1955	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH63_1959	COG0745	RESPONSE REGULATOR receiver
CH63_196	COG0628	permease
CH63_1960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH63_1961	COG2183	response to ionizing radiation
CH63_1962	COG1918	ferrous iron import across plasma membrane
CH63_1969	COG1640	4-alpha-glucanotransferase
CH63_197	COG0277	FAD linked oxidase domain protein
CH63_197	COG0247	lactate metabolic process
CH63_1970	COG0058	SHG alpha-glucan phosphorylase activity
CH63_1971	COG0058	SHG alpha-glucan phosphorylase activity
CH63_1975	COG1349	DNA-binding transcription factor activity
CH63_1978	COG2801	Transposase and inactivated derivatives
CH63_198	COG2050	protein possibly involved in aromatic compounds catabolism
CH63_199	COG0316	Belongs to the HesB IscA family
CH63_1992	COG1175	transmembrane transport
CH63_1993	COG3833	ABC-type maltose transport systems, permease component
CH63_1996	COG0527	aspartate kinase activity
CH63_20	COG0318	PFAM AMP-dependent synthetase and ligase
CH63_200	COG0719	Fe-S assembly protein
CH63_2001	COG1414	Transcriptional regulator
CH63_2002	COG1414	Transcriptional regulator
CH63_2004	COG2224	Isocitrate lyase
CH63_2005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH63_201	COG0396	ATPase activity
CH63_2015	COG2186	Transcriptional regulator
CH63_2017	COG0477	Major facilitator Superfamily
CH63_2018	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_202	COG0719	Fe-S assembly protein
CH63_2024	COG1522	sequence-specific DNA binding
CH63_2025	COG0716	FMN binding
CH63_2028	COG3312	ion transport
CH63_2038	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH63_2039	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH63_2040	COG0573	inorganic phosphate transmembrane transporter activity
CH63_2041	COG0581	inorganic phosphate transmembrane transporter activity
CH63_2043	COG0704	Plays a role in the regulation of phosphate uptake
CH63_2045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_2046	COG0765	amino acid transport
CH63_2047	COG0765	amino acid transport
CH63_2048	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_2049	COG2252	PERMEase
CH63_205	COG1376	ErfK ybiS ycfS ynhG family protein
CH63_205	COG1388	LysM domain
CH63_2054	COG0706	membrane insertase activity
CH63_2057	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH63_2060	COG0592	DNA-directed DNA polymerase activity
CH63_2061	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH63_2062	COG0187	DNA topoisomerase II activity
CH63_2063	COG0561	phosphatase activity
CH63_2064	COG2801	Transposase and inactivated derivatives
CH63_2067	COG2423	ornithine cyclodeaminase activity
CH63_2068	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH63_2069	COG0823	Involved in the tonB-independent uptake of proteins
CH63_2070	COG0823	Involved in the tonB-independent uptake of proteins
CH63_2071	COG5645	(Lipo)protein
CH63_2075	COG3977	Valine--pyruvate aminotransferase
CH63_2077	COG0366	Alpha amylase catalytic
CH63_2080	COG2885	chlorophyll binding
CH63_2082	COG2818	Glycosylase
CH63_2087	COG2213	PTS system mannitol-specific
CH63_2087	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_2089	COG3722	fumarate hydratase activity
CH63_209	COG4238	major outer membrane lipoprotein
CH63_2096	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH63_2098	COG0243	molybdopterin cofactor binding
CH63_2098	COG3383	formate dehydrogenase (NAD+) activity
CH63_2099	COG3383	formate dehydrogenase (NAD+) activity
CH63_2099	COG0243	molybdopterin cofactor binding
CH63_21	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH63_2100	COG0437	4 iron, 4 sulfur cluster binding
CH63_2101	COG2864	formate dehydrogenase
CH63_2112	COG2801	Transposase and inactivated derivatives
CH63_2114	COG3274	enterobacterial common antigen metabolic process
CH63_2116	COG3188	usher protein
CH63_2117	COG3188	usher protein
CH63_2118	COG3121	Chaperone
CH63_2120	COG1070	Carbohydrate kinase
CH63_2122	COG4213	ABC transporter substrate-binding protein
CH63_2124	COG4214	carbohydrate transport
CH63_2125	COG1609	Transcriptional regulator
CH63_2125	COG2207	Transcriptional regulator
CH63_2127	COG0582	viral genome integration into host DNA
CH63_2134	COG4604	ABC transporter, ATP-binding protein
CH63_2136	COG4605	iron ion homeostasis
CH63_2138	COG4607	ABC-type enterochelin transport system periplasmic component
CH63_214	COG0307	riboflavin synthase, alpha
CH63_2141	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH63_2144	COG2986	histidine ammonia-lyase
CH63_2147	COG2194	sulfuric ester hydrolase activity
CH63_2148	COG2197	response regulator
CH63_215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH63_2150	COG2271	Major facilitator Superfamily
CH63_2154	COG2831	hemolysin activation secretion protein
CH63_2156	COG0747	negative chemotaxis
CH63_2157	COG0601	transmembrane transport
CH63_2158	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_2159	COG0444	Belongs to the ABC transporter superfamily
CH63_216	COG2814	Major facilitator Superfamily
CH63_2160	COG4608	Belongs to the ABC transporter superfamily
CH63_2161	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH63_2162	COG2200	EAL domain
CH63_2162	COG2199	diguanylate cyclase activity
CH63_2163	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH63_2167	COG0612	Peptidase, M16
CH63_2168	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_2169	COG1942	4-Oxalocrotonate Tautomerase
CH63_217	COG1609	Transcriptional regulator
CH63_2170	COG2200	EAL domain
CH63_2172	COG2134	cdp-diacylglycerol pyrophosphatase
CH63_2174	COG1295	ribonuclease BN
CH63_2179	COG1929	Belongs to the glycerate kinase type-1 family
CH63_218	COG0583	DNA-binding transcription factor activity
CH63_2180	COG2610	gluconate transmembrane transporter activity
CH63_2181	COG3835	regulator
CH63_2182	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH63_2183	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH63_2184	COG0339	signal peptide processing
CH63_2188	COG0589	response to stress
CH63_2191	COG0306	phosphate transporter
CH63_2192	COG2081	HI0933 family
CH63_2195	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_2196	COG1879	ABC-type sugar transport system periplasmic component
CH63_2198	COG0191	fructose-bisphosphate aldolase activity
CH63_22	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH63_220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH63_2200	COG0745	RESPONSE REGULATOR receiver
CH63_2202	COG1741	Belongs to the pirin family
CH63_2203	COG1609	Transcriptional regulator
CH63_2204	COG2610	gluconate transmembrane transporter activity
CH63_2205	COG3265	gluconokinase activity
CH63_2209	COG2095	MarC family integral membrane protein
CH63_221	COG0791	NLP P60 protein
CH63_2210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH63_2216	COG4932	domain protein
CH63_2216	COG1388	LysM domain
CH63_2216	COG2373	Large extracellular alpha-helical protein
CH63_2217	COG3275	phosphorelay sensor kinase activity
CH63_2222	COG0058	SHG alpha-glucan phosphorylase activity
CH63_2223	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH63_2226	COG2801	Transposase and inactivated derivatives
CH63_223	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH63_224	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH63_2241	COG3501	Rhs element vgr protein
CH63_2243	COG3209	COG3209 Rhs family protein
CH63_2246	COG0673	inositol 2-dehydrogenase activity
CH63_2247	COG2207	Transcriptional regulator
CH63_2247	COG1917	Cupin 2, conserved barrel domain protein
CH63_2248	COG1869	D-ribose catabolic process
CH63_2249	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_225	COG0346	lactoylglutathione lyase activity
CH63_2251	COG0431	NADPH-dependent FMN reductase
CH63_2252	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH63_2254	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH63_2256	COG3077	Addiction module antitoxin, RelB DinJ family
CH63_2257	COG2252	PERMEase
CH63_2258	COG0025	NhaP-type Na H and K H
CH63_2260	COG1560	Kdo2-lipid A biosynthetic process
CH63_2262	COG1129	ABC transporter
CH63_2263	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_2265	COG1069	ribulokinase activity
CH63_2267	COG0625	glutathione transferase activity
CH63_227	COG1902	pentaerythritol trinitrate reductase activity
CH63_2271	COG1278	Cold shock
CH63_2272	COG1278	Cold shock
CH63_2273	COG3133	Outer membrane lipoprotein
CH63_2274	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH63_2276	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH63_228	COG1309	transcriptional regulator
CH63_2280	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH63_2281	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH63_2283	COG4145	pantothenate transmembrane transporter activity
CH63_2284	COG3924	membrane
CH63_2286	COG0439	Biotin carboxylase
CH63_2287	COG0511	ligase activity, forming carbon-carbon bonds
CH63_229	COG2194	sulfuric ester hydrolase activity
CH63_2290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH63_2291	COG0604	alcohol dehydrogenase
CH63_2292	COG2200	EAL domain
CH63_2292	COG2199	diguanylate cyclase activity
CH63_2293	COG1077	Cell shape determining protein MreB Mrl
CH63_2294	COG1792	Involved in formation and maintenance of cell shape
CH63_2295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH63_2297	COG1530	ribonuclease E activity
CH63_2298	COG3164	Protein of unknown function
CH63_2299	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH63_23	COG2894	cell division
CH63_2300	COG0312	modulator of DNA gyrase
CH63_231	COG3133	Outer membrane lipoprotein
CH63_2310	COG0583	DNA-binding transcription factor activity
CH63_2314	COG1012	belongs to the aldehyde dehydrogenase family
CH63_2317	COG2732	(Barnase) inhibitor
CH63_2319	COG0312	modulator of DNA gyrase
CH63_2321	COG3783	Cytochrome b(562)
CH63_2322	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH63_2323	COG0366	Alpha amylase catalytic
CH63_2324	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_2324	COG1263	PTS System
CH63_2325	COG1609	Transcriptional regulator
CH63_233	COG3895	Periplasmic Protein
CH63_2330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_2332	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_2334	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH63_2335	COG1137	ATPase activity
CH63_2336	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH63_2337	COG3117	lipopolysaccharide transmembrane transporter activity
CH63_2338	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH63_2339	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH63_2339	COG0517	IMP dehydrogenase activity
CH63_2340	COG0530	calcium, potassium:sodium antiporter activity
CH63_2341	COG1127	ABC transporter
CH63_2342	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH63_2343	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH63_2344	COG2854	intermembrane phospholipid transfer
CH63_2345	COG3113	response to antibiotic
CH63_2346	COG5007	Belongs to the BolA IbaG family
CH63_2348	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH63_2349	COG1943	Transposase
CH63_2350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH63_2351	COG3105	Protein conserved in bacteria
CH63_2353	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH63_2356	COG0625	glutathione transferase activity
CH63_2357	COG2969	positive regulation of protein catabolic process
CH63_2359	COG0493	'glutamate synthase
CH63_2360	COG0069	glutamate synthase activity
CH63_2360	COG0067	glutamate synthase
CH63_2360	COG0070	glutamate synthase
CH63_2361	COG1242	4 iron, 4 sulfur cluster binding
CH63_2362	COG5002	protein histidine kinase activity
CH63_2362	COG2198	Histidine kinase
CH63_2362	COG0784	Response regulator, receiver
CH63_2363	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH63_2365	COG2823	Periplasmic or secreted lipoprotein
CH63_2369	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH63_237	COG0625	glutathione transferase activity
CH63_2370	COG1741	Belongs to the pirin family
CH63_2371	COG0583	DNA-binding transcription factor activity
CH63_2372	COG0435	Glutathione S-transferase
CH63_2381	COG3328	transposase activity
CH63_2382	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH63_2384	COG3084	Protein conserved in bacteria
CH63_2385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH63_2386	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH63_2387	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH63_2387	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH63_2389	COG1943	Transposase
CH63_2392	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH63_2394	COG3852	Histidine kinase
CH63_2395	COG0174	glutamine synthetase
CH63_2397	COG1011	Hydrolase
CH63_2398	COG1295	ribonuclease BN
CH63_240	COG3104	oligopeptide transport
CH63_2402	COG1401	restriction endodeoxyribonuclease activity
CH63_2404	COG2963	transposase activity
CH63_2414	COG4269	membrane
CH63_2416	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH63_2417	COG2207	Transcriptional regulator
CH63_2418	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH63_2419	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH63_242	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH63_242	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH63_2420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_2420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH63_2420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_2429	COG2390	Transcriptional regulator
CH63_243	COG4172	Belongs to the ABC transporter superfamily
CH63_2430	COG2390	Transcriptional regulator
CH63_2432	COG0859	PFAM glycosyl transferase family 9
CH63_2435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_2436	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_2439	COG3706	GGDEF domain
CH63_2443	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH63_2444	COG0456	acetyltransferase
CH63_2446	COG2823	Periplasmic or secreted lipoprotein
CH63_2448	COG4667	esterase of the alpha-beta hydrolase superfamily
CH63_2449	COG0084	hydrolase, TatD family'
CH63_245	COG4171	peptide transport system, permease
CH63_2450	COG0084	hydrolase, TatD family'
CH63_2451	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH63_2452	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH63_2457	COG3726	membrane protein affecting hemolysin expression
CH63_2458	COG0560	Phosphoserine phosphatase
CH63_246	COG4168	peptide transport system, permease
CH63_2462	COG0488	(ABC) transporter
CH63_2463	COG0488	(ABC) transporter
CH63_2464	COG2885	chlorophyll binding
CH63_2465	COG2199	diguanylate cyclase activity
CH63_2468	COG0741	lytic transglycosylase activity
CH63_247	COG4166	transmembrane transport
CH63_2470	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH63_2471	COG3708	Transcriptional regulator
CH63_2471	COG2207	Transcriptional regulator
CH63_2474	COG3045	CreA protein
CH63_2475	COG0745	RESPONSE REGULATOR receiver
CH63_2484	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH63_2487	COG1584	GPR1 FUN34 yaaH family protein
CH63_249	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH63_2491	COG0583	DNA-binding transcription factor activity
CH63_2493	COG0196	riboflavin kinase activity
CH63_2496	COG1047	Peptidyl-prolyl cis-trans
CH63_2498	COG1943	Transposase
CH63_250	COG1842	Phage shock protein A
CH63_2500	COG0505	Belongs to the CarA family
CH63_2501	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH63_2502	COG1280	lysine exporter protein (LysE YggA)
CH63_2503	COG2966	Psort location CytoplasmicMembrane, score
CH63_2505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH63_2506	COG1943	Transposase
CH63_2508	COG2721	sulfolactate sulfo-lyase activity
CH63_2509	COG0246	Mannitol dehydrogenase
CH63_2511	COG2271	Major facilitator Superfamily
CH63_2514	COG0586	Pfam SNARE associated Golgi protein
CH63_2517	COG4575	ribosome binding
CH63_2518	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH63_252	COG1983	PspC domain protein
CH63_2520	COG2259	Doxx family
CH63_2521	COG0435	Glutathione S-transferase
CH63_2524	COG0494	nUDIX hydrolase
CH63_2529	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH63_2530	COG0849	cell division
CH63_2531	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH63_2535	COG0772	Belongs to the SEDS family
CH63_2538	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH63_2539	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH63_254	COG3106	COG3106 Predicted ATPase
CH63_2540	COG0768	penicillin binding
CH63_2541	COG3116	cell division
CH63_2545	COG1609	Transcriptional regulator
CH63_2546	COG1943	Transposase
CH63_2548	COG0028	Belongs to the TPP enzyme family
CH63_2549	COG1022	Amp-dependent synthetase and ligase
CH63_2552	COG1943	Transposase
CH63_2554	COG0473	3-isopropylmalate dehydrogenase activity
CH63_2557	COG2814	Major facilitator Superfamily
CH63_2560	COG4143	(ABC) transporter
CH63_2561	COG1178	ABC-type Fe3 transport system permease component
CH63_2563	COG0586	Pfam SNARE associated Golgi protein
CH63_2564	COG0417	DNA replication proofreading
CH63_2576	COG3501	Rhs element vgr protein
CH63_2586	COG0564	pseudouridine synthase activity
CH63_2587	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH63_2589	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH63_259	COG1943	Transposase
CH63_2590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH63_2595	COG1943	Transposase
CH63_2598	COG0673	inositol 2-dehydrogenase activity
CH63_2599	COG1451	nucleotide metabolic process
CH63_260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH63_2602	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH63_2602	COG1902	pentaerythritol trinitrate reductase activity
CH63_2603	COG3247	response to pH
CH63_2606	COG4245	von Willebrand factor, type A
CH63_2609	COG4245	von Willebrand factor, type A
CH63_261	COG4948	Mandelate Racemase Muconate Lactonizing
CH63_2610	COG2831	hemolysin activation secretion protein
CH63_2611	COG3210	domain, Protein
CH63_2612	COG3210	domain, Protein
CH63_2614	COG3210	domain, Protein
CH63_2616	COG3210	domain, Protein
CH63_262	COG2866	Carboxypeptidase
CH63_2620	COG3842	ATPase activity
CH63_2621	COG3459	Glycosyltransferase 36 associated
CH63_2622	COG1609	Transcriptional regulator
CH63_2623	COG1653	transport
CH63_2625	COG0395	ABC-type sugar transport system, permease component
CH63_2629	COG1289	transmembrane transporter activity
CH63_263	COG4166	transmembrane transport
CH63_2638	COG0251	oxidation-reduction process
CH63_2653	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH63_2654	COG0358	DNA primase activity
CH63_2658	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH63_266	COG0657	acetylesterase activity
CH63_266	COG2755	lipolytic protein G-D-S-L family
CH63_2661	COG4991	sh3 domain protein
CH63_2662	COG3025	triphosphatase activity
CH63_2665	COG0531	amino acid
CH63_2669	COG3384	dioxygenase
CH63_2670	COG0754	glutathionylspermidine amidase activity
CH63_2673	COG1538	Outer membrane efflux protein
CH63_2674	COG0494	nUDIX hydrolase
CH63_2675	COG3151	Protein conserved in bacteria
CH63_2676	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH63_2677	COG3150	esterase
CH63_2678	COG0187	DNA topoisomerase II activity
CH63_2679	COG0583	DNA-binding transcription factor activity
CH63_2680	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH63_2681	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH63_2682	COG0204	Acyl-transferase
CH63_2683	COG2132	Multicopper oxidase
CH63_2686	COG0656	L-ascorbic acid biosynthetic process
CH63_2687	COG1979	alcohol dehydrogenase
CH63_2688	COG2207	Transcriptional regulator
CH63_2689	COG0586	Pfam SNARE associated Golgi protein
CH63_269	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH63_269	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH63_269	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH63_269	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH63_2690	COG0626	cystathionine gamma-synthase activity
CH63_2691	COG0811	peptide transport
CH63_2693	COG0848	biopolymer transport protein
CH63_27	COG2951	lytic endotransglycosylase activity
CH63_2703	COG4964	Belongs to the GSP D family
CH63_2704	COG4964	Belongs to the GSP D family
CH63_271	COG1285	pathogenesis
CH63_2711	COG4592	Periplasmic binding protein
CH63_2715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH63_2716	COG1684	flagellar biosynthetic protein fliR
CH63_2717	COG1987	bacterial-type flagellum assembly
CH63_272	COG3042	response to heat
CH63_2721	COG2204	response regulator
CH63_273	COG3187	Heat shock protein
CH63_2730	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH63_2731	COG1815	bacterial-type flagellum-dependent cell motility
CH63_2732	COG1558	bacterial-type flagellum-dependent cell motility
CH63_2733	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH63_2734	COG1749	Flagellar hook protein flgE
CH63_2735	COG4787	bacterial-type flagellum-dependent cell motility
CH63_2736	COG4786	Flagellar basal body rod
CH63_2737	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH63_2738	COG1706	bacterial-type flagellum-dependent cell motility
CH63_274	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH63_2740	COG1256	bacterial-type flagellum assembly
CH63_2744	COG3710	Transcriptional regulator
CH63_2747	COG2801	Transposase and inactivated derivatives
CH63_275	COG2911	Protein conserved in bacteria
CH63_2750	COG0513	Belongs to the DEAD box helicase family
CH63_2753	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH63_2757	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_2762	COG3153	acetyltransferase
CH63_2766	COG1653	transport
CH63_2768	COG0395	ABC-type sugar transport system, permease component
CH63_2769	COG3842	ATPase activity
CH63_277	COG3784	Protein of unknown function (DUF1318)
CH63_2772	COG0702	epimerase
CH63_2773	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH63_2774	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH63_2775	COG3454	Phosphonate metabolism
CH63_2776	COG4778	phosphonate C-P lyase system protein PhnL
CH63_2777	COG4107	phosphonate C-P lyase system protein PhnK
CH63_2778	COG3627	carbon phosphorus lyase activity
CH63_2779	COG3626	phosphonate metabolism
CH63_278	COG0246	Mannitol dehydrogenase
CH63_2780	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH63_2781	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH63_2782	COG3624	Phosphonate C-P lyase system protein PhnG
CH63_2783	COG2188	Transcriptional regulator
CH63_2787	COG4608	Belongs to the ABC transporter superfamily
CH63_2788	COG0444	Belongs to the ABC transporter superfamily
CH63_2789	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_279	COG2390	Transcriptional regulator
CH63_2790	COG0601	transmembrane transport
CH63_2792	COG2731	YhcH YjgK YiaL family protein
CH63_2793	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CH63_2794	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH63_2796	COG0525	valine-tRNA ligase activity
CH63_2797	COG2927	DNA polymerase III (CHI subunit)
CH63_2799	COG0795	lipopolysaccharide-transporting ATPase activity
CH63_28	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH63_2800	COG0795	lipopolysaccharide-transporting ATPase activity
CH63_2802	COG0582	viral genome integration into host DNA
CH63_281	COG1643	Atp-dependent helicase
CH63_2810	COG0237	dephospho-CoA kinase activity
CH63_2812	COG1459	type II secretion system
CH63_2813	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH63_2814	COG4969	Belongs to the N-Me-Phe pilin family
CH63_2816	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH63_2817	COG3725	Membrane protein required for beta-lactamase induction
CH63_2818	COG3725	Membrane protein required for beta-lactamase induction
CH63_2819	COG1113	amino acid transport
CH63_2820	COG2186	Transcriptional regulator
CH63_2821	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH63_2822	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH63_2823	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH63_2824	COG1943	Transposase
CH63_2825	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH63_2827	COG0697	spore germination
CH63_2831	COG2132	Multicopper oxidase
CH63_2832	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH63_2833	COG0288	reversible hydration of carbon dioxide
CH63_2834	COG1131	(ABC) transporter
CH63_2835	COG0842	Transport permease protein
CH63_2837	COG0726	polysaccharide deacetylase
CH63_284	COG3591	Belongs to the peptidase S1B family
CH63_2841	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH63_2842	COG0617	tRNA 3'-terminal CCA addition
CH63_2843	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH63_2844	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH63_2846	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH63_2847	COG1643	Atp-dependent helicase
CH63_2848	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH63_2849	COG1120	ATPase activity
CH63_2850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH63_2851	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_2855	COG2860	membrane
CH63_2857	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH63_2859	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH63_286	COG3038	cytochrome b561
CH63_2860	COG2205	protein histidine kinase activity
CH63_2860	COG3437	response regulator, receiver
CH63_2860	COG3850	Histidine kinase
CH63_2860	COG4999	Histidine kinase
CH63_2861	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH63_2862	COG3956	TIGRFAM MazG family protein
CH63_2866	COG0602	queuosine metabolic process
CH63_2867	COG0720	synthase
CH63_2878	COG0529	Catalyzes the synthesis of activated sulfate
CH63_2881	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CH63_2886	COG1388	LysM domain
CH63_2886	COG4942	peptidase
CH63_2887	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH63_2888	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH63_2889	COG0698	ribose 5-phosphate isomerase
CH63_2890	COG1063	alcohol dehydrogenase
CH63_2891	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_2892	COG2376	Dihydroxyacetone kinase
CH63_2895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH63_2899	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_290	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH63_2900	COG1858	cytochrome C peroxidase
CH63_2902	COG4771	TonB-dependent receptor
CH63_2904	COG0024	Methionine aminopeptidase
CH63_2906	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH63_2906	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH63_2907	COG1070	Carbohydrate kinase
CH63_2908	COG3623	hexulose-6-phosphate isomerase
CH63_2909	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_291	COG2205	protein histidine kinase activity
CH63_2910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_2911	COG1129	ABC transporter
CH63_2912	COG1943	Transposase
CH63_2914	COG1349	DNA-binding transcription factor activity
CH63_2915	COG0235	Class ii aldolase
CH63_2916	COG0243	molybdopterin cofactor binding
CH63_2917	COG0437	4 iron, 4 sulfur cluster binding
CH63_2918	COG3302	dmso reductase anchor subunit
CH63_2919	COG3381	protein complex oligomerization
CH63_292	COG0745	RESPONSE REGULATOR receiver
CH63_2920	COG3038	cytochrome b561
CH63_2921	COG3783	Cytochrome b(562)
CH63_2925	COG1129	ABC transporter
CH63_2926	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_2927	COG3959	Transketolase, thiamine diphosphate binding domain
CH63_2928	COG3958	Transketolase
CH63_2929	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH63_2936	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH63_2937	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH63_294	COG0531	amino acid
CH63_2942	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_2943	COG1238	metal cluster binding
CH63_2944	COG2918	glutathione biosynthetic process
CH63_2947	COG4536	flavin adenine dinucleotide binding
CH63_2948	COG4137	Cytochrome C assembly protein
CH63_2949	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH63_2954	COG1943	Transposase
CH63_2955	COG3137	Salt-induced outer membrane protein
CH63_2956	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_2957	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_2958	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_2959	COG3279	Response regulator of the LytR AlgR family
CH63_296	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH63_2960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH63_2961	COG0287	Prephenate dehydrogenase
CH63_2961	COG1605	Chorismate mutase
CH63_2962	COG0077	Prephenate dehydratase
CH63_2962	COG1605	Chorismate mutase
CH63_2966	COG1605	Chorismate mutase
CH63_2966	COG0077	Prephenate dehydratase
CH63_2967	COG1943	Transposase
CH63_2968	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH63_2969	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH63_297	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH63_2970	COG0564	pseudouridine synthase activity
CH63_2972	COG0542	response to heat
CH63_2979	COG5544	Lipoprotein
CH63_298	COG0589	response to stress
CH63_2980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH63_2981	COG1042	CoA-binding domain protein
CH63_2981	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH63_2981	COG0045	succinate-CoA ligase (ADP-forming) activity
CH63_2983	COG3118	belongs to the thioredoxin family
CH63_2984	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH63_2985	COG2814	Major facilitator Superfamily
CH63_2986	COG1566	PFAM secretion protein HlyD family protein
CH63_2987	COG1846	Transcriptional regulator
CH63_2989	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH63_299	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH63_2990	COG2814	Major facilitator Superfamily
CH63_2999	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH63_30	COG0582	viral genome integration into host DNA
CH63_300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH63_3005	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH63_3007	COG1960	acyl-CoA dehydrogenase activity
CH63_3009	COG3034	peptidoglycan biosynthetic process
CH63_3010	COG0121	glutamine amidotransferase
CH63_3011	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH63_3012	COG1805	sodium ion transport
CH63_3013	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH63_3017	COG1477	protein flavinylation
CH63_3021	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH63_3023	COG1943	Transposase
CH63_303	COG1011	Hydrolase
CH63_3031	COG1943	Transposase
CH63_3034	COG2226	methyltransferase
CH63_304	COG0440	acetolactate synthase activity
CH63_3042	COG1940	carbohydrate kinase activity
CH63_3043	COG0419	ATPase involved in DNA repair
CH63_3044	COG0420	3'-5' exonuclease activity
CH63_3045	COG0745	RESPONSE REGULATOR receiver
CH63_3046	COG5002	protein histidine kinase activity
CH63_3048	COG1114	Component of the transport system for branched-chain amino acids
CH63_3050	COG0366	Alpha amylase catalytic
CH63_3054	COG0450	alkyl hydroperoxide reductase
CH63_3055	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CH63_3056	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CH63_3058	COG1862	Preprotein translocase
CH63_3059	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH63_3060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH63_3065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH63_3065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH63_3068	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH63_3069	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH63_3072	COG0142	geranyltranstransferase activity
CH63_3075	COG0693	protein deglycase activity
CH63_3076	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH63_3078	COG2814	Major facilitator Superfamily
CH63_3080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH63_3081	COG1845	cytochrome c oxidase, subunit III
CH63_3082	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH63_3083	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH63_3086	COG2223	nitrite transmembrane transporter activity
CH63_3087	COG3056	Lipoprotein
CH63_3088	COG0271	Belongs to the BolA IbaG family
CH63_3093	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH63_3094	COG0776	regulation of translation
CH63_3095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH63_3096	COG1555	photosystem II stabilization
CH63_3097	COG0824	Thioesterase
CH63_3099	COG4533	DNA binding
CH63_3102	COG1522	sequence-specific DNA binding
CH63_3103	COG1132	(ABC) transporter
CH63_3104	COG1132	(ABC) transporter
CH63_3105	COG0347	Belongs to the P(II) protein family
CH63_3106	COG0004	ammonium transporteR
CH63_3107	COG1946	Acyl-CoA thioesterase
CH63_3108	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH63_3109	COG3695	enzyme binding
CH63_3113	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH63_3115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_3116	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_3117	COG1309	transcriptional regulator
CH63_3118	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH63_3119	COG3264	Mechanosensitive ion channel
CH63_3119	COG1196	nuclear chromosome segregation
CH63_312	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH63_3121	COG2832	Protein of unknown function (DUF454)
CH63_3123	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH63_3129	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_3129	COG0543	2 iron, 2 sulfur cluster binding
CH63_3130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_3130	COG0543	2 iron, 2 sulfur cluster binding
CH63_3134	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_314	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH63_3143	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH63_3144	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH63_3145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_3149	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH63_315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH63_3150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_3151	COG4651	solute:proton antiporter activity
CH63_3151	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH63_3152	COG2223	nitrite transmembrane transporter activity
CH63_3153	COG0737	Belongs to the 5'-nucleotidase family
CH63_3156	COG0737	Belongs to the 5'-nucleotidase family
CH63_3159	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH63_316	COG1879	ABC-type sugar transport system periplasmic component
CH63_3160	COG3735	TraB family
CH63_3161	COG2217	Heavy metal translocating P-type atpase
CH63_3162	COG0789	Transcriptional regulator
CH63_3163	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH63_3164	COG0330	HflC and HflK could
CH63_3165	COG3118	belongs to the thioredoxin family
CH63_3166	COG0300	oxidoreductase activity
CH63_3167	COG2755	lipolytic protein G-D-S-L family
CH63_3168	COG4181	ATPase activity
CH63_3169	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH63_3170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH63_3171	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH63_3173	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH63_3176	COG1943	Transposase
CH63_3177	COG2501	S4 domain
CH63_318	COG1609	Transcriptional regulator
CH63_3185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH63_3186	COG4589	Belongs to the CDS family
CH63_3188	COG2267	carboxylic ester hydrolase activity
CH63_3189	COG2453	phosphatase
CH63_3189	COG0671	phosphoesterase, PA-phosphatase related
CH63_319	COG0038	chloride channel
CH63_3196	COG0667	Aldo Keto reductase
CH63_3197	COG0656	L-ascorbic acid biosynthetic process
CH63_320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH63_3202	COG3328	transposase activity
CH63_3203	COG2850	peptidyl-arginine hydroxylation
CH63_3214	COG3423	Transcriptional regulator
CH63_3215	COG4953	penicillin-binding protein 1C
CH63_3217	COG1943	Transposase
CH63_3218	COG2373	Large extracellular alpha-helical protein
CH63_322	COG1940	carbohydrate kinase activity
CH63_3224	COG3962	Belongs to the TPP enzyme family
CH63_3225	COG0673	inositol 2-dehydrogenase activity
CH63_3226	COG0673	inositol 2-dehydrogenase activity
CH63_3227	COG1879	ABC-type sugar transport system periplasmic component
CH63_3228	COG1129	ABC transporter
CH63_3229	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_323	COG0583	DNA-binding transcription factor activity
CH63_3230	COG0673	inositol 2-dehydrogenase activity
CH63_3231	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_3233	COG3718	enzyme involved in inositol metabolism
CH63_3235	COG5265	(ABC) transporter
CH63_324	COG2814	Major facilitator Superfamily
CH63_3240	COG2197	response regulator
CH63_3241	COG1278	Cold shock
CH63_3242	COG1278	Cold shock
CH63_3243	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH63_3244	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH63_3248	COG1686	Belongs to the peptidase S11 family
CH63_3249	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH63_3250	COG0772	Belongs to the SEDS family
CH63_3251	COG0768	penicillin binding
CH63_3253	COG0799	negative regulation of ribosome biogenesis
CH63_3255	COG1466	dna polymerase III delta subunit
CH63_3258	COG2888	peptidyl-tyrosine sulfation
CH63_3259	COG1126	abc transporter atp-binding protein
CH63_326	COG0114	fumarate hydratase activity
CH63_3260	COG0765	amino acid transport
CH63_3261	COG0765	amino acid transport
CH63_3263	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH63_3264	COG4535	Mg2 and Co2 transporter CorC
CH63_3266	COG1702	phosphate starvation-inducible protein PhoH
CH63_3268	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH63_3275	COG0367	asparagine synthase
CH63_3276	COG0647	UMP catabolic process
CH63_3277	COG1846	Transcriptional regulator
CH63_3277	COG1940	carbohydrate kinase activity
CH63_3278	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH63_328	COG5339	Protein conserved in bacteria
CH63_3280	COG2190	(PTS) system
CH63_3280	COG1263	PTS System
CH63_3280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_3281	COG1943	Transposase
CH63_3287	COG0735	belongs to the Fur family
CH63_3291	COG0596	Alpha beta hydrolase
CH63_3293	COG2963	transposase activity
CH63_3294	COG0582	viral genome integration into host DNA
CH63_3298	COG2113	Glycine betaine
CH63_3299	COG4176	ABC-type proline glycine betaine transport system permease component
CH63_330	COG0385	Bile acid
CH63_3300	COG4175	Glycine betaine
CH63_3301	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH63_3309	COG1278	Cold shock
CH63_331	COG0673	inositol 2-dehydrogenase activity
CH63_3310	COG0747	negative chemotaxis
CH63_3312	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_3313	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH63_3314	COG1124	(ABC) transporter
CH63_3321	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH63_3323	COG4413	Urea transporter
CH63_3324	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH63_3326	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH63_3327	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH63_3328	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH63_3329	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH63_333	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_3330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH63_3331	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH63_3332	COG1917	Cupin 2, conserved barrel domain protein
CH63_3332	COG2169	Transcriptional regulator
CH63_3336	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH63_3337	COG0033	Phosphoglucomutase
CH63_3341	COG0745	RESPONSE REGULATOR receiver
CH63_3342	COG2205	protein histidine kinase activity
CH63_3347	COG3272	Protein of unknown function (DUF1722)
CH63_3349	COG5212	phosphodiesterase
CH63_335	COG1879	ABC-type sugar transport system periplasmic component
CH63_3350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH63_3352	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH63_3353	COG1984	allophanate hydrolase subunit 2
CH63_3366	COG0513	Belongs to the DEAD box helicase family
CH63_3368	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH63_3370	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH63_3371	COG3026	antisigma factor binding
CH63_3372	COG3086	response to oxidative stress
CH63_3375	COG0681	Belongs to the peptidase S26 family
CH63_3379	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH63_3381	COG1943	Transposase
CH63_3382	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_3383	COG1737	Transcriptional regulator
CH63_3386	COG0560	Phosphoserine phosphatase
CH63_3387	COG0590	tRNA wobble adenosine to inosine editing
CH63_339	COG2274	protein secretion by the type I secretion system
CH63_3394	COG2205	protein histidine kinase activity
CH63_3395	COG3170	Tfp pilus assembly protein FimV
CH63_3396	COG2204	response regulator
CH63_3397	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH63_3397	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH63_3398	COG0347	Belongs to the P(II) protein family
CH63_3399	COG2188	Transcriptional regulator
CH63_340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_3400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_3400	COG1017	nitric oxide dioxygenase activity
CH63_3403	COG3711	transcriptional antiterminator
CH63_3404	COG2814	Major facilitator Superfamily
CH63_3405	COG3683	transport system, periplasmic component
CH63_3406	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH63_3407	COG1943	Transposase
CH63_3408	COG0483	inositol monophosphate 1-phosphatase activity
CH63_3411	COG1104	cysteine desulfurase activity
CH63_3412	COG0822	iron-sulfur transferase activity
CH63_3415	COG0443	Heat shock 70 kDa protein
CH63_3416	COG0633	Ferredoxin
CH63_3417	COG2975	iron-sulfur cluster assembly
CH63_3421	COG3468	outer membrane autotransporter barrel domain protein
CH63_3422	COG3468	outer membrane autotransporter barrel domain protein
CH63_3431	COG2976	Protein conserved in bacteria
CH63_3432	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH63_3435	COG1645	bacterial-type flagellum-dependent swarming motility
CH63_3437	COG0517	IMP dehydrogenase activity
CH63_3437	COG0516	GMP reductase activity
CH63_3439	COG1943	Transposase
CH63_3446	COG3328	transposase activity
CH63_3447	COG0513	Belongs to the DEAD box helicase family
CH63_3450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH63_3452	COG1686	Belongs to the peptidase S11 family
CH63_3453	COG0277	FAD linked oxidase domain protein
CH63_3457	COG2261	transglycosylase associated protein
CH63_3459	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH63_3463	COG4807	Protein conserved in bacteria
CH63_3466	COG1122	ATPase activity
CH63_3467	COG0410	ABC transporter
CH63_347	COG3708	Transcriptional regulator
CH63_347	COG2207	Transcriptional regulator
CH63_3470	COG2897	thiosulfate sulfurtransferase activity
CH63_3473	COG1174	glycine betaine transport
CH63_3474	COG1125	glycine betaine transport
CH63_3475	COG1174	glycine betaine transport
CH63_3476	COG0531	amino acid
CH63_3477	COG1982	Orn Lys Arg decarboxylase major
CH63_3479	COG0697	spore germination
CH63_348	COG4658	electron transport chain
CH63_3481	COG1199	ATP-dependent helicase activity
CH63_3484	COG0814	amino acid
CH63_3487	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_349	COG4659	FMN binding
CH63_3492	COG2205	protein histidine kinase activity
CH63_3492	COG0784	Response regulator, receiver
CH63_3494	COG2198	Histidine kinase
CH63_3494	COG0642	Histidine kinase
CH63_3495	COG2198	Histidine kinase
CH63_3495	COG0642	Histidine kinase
CH63_3496	COG2223	nitrite transmembrane transporter activity
CH63_3498	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CH63_3502	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH63_351	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH63_3510	COG3395	kinase activity
CH63_3511	COG0235	Class ii aldolase
CH63_3512	COG1349	DNA-binding transcription factor activity
CH63_3513	COG3622	Belongs to the hyi family
CH63_3517	COG4386	tail sheath protein
CH63_352	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_3526	COG3299	homolog of phage Mu protein gp47
CH63_353	COG2271	Major facilitator Superfamily
CH63_3530	COG1737	Transcriptional regulator
CH63_3532	COG2723	6-phospho-beta-galactosidase activity
CH63_3536	COG3157	Type VI secretion system effector, Hcp
CH63_3539	COG3083	sulfuric ester hydrolase activity
CH63_3540	COG3082	Protein of unknown function (DUF1414)
CH63_3542	COG1943	Transposase
CH63_3544	COG1061	Type III restriction enzyme res subunit
CH63_3545	COG1187	pseudouridine synthase activity
CH63_3546	COG2814	Major facilitator Superfamily
CH63_3548	COG4172	Belongs to the ABC transporter superfamily
CH63_3549	COG4239	(ABC) transporter, permease
CH63_355	COG1966	Carbon starvation protein
CH63_3550	COG4174	ABC transporter (Permease)
CH63_3551	COG4166	transmembrane transport
CH63_3552	COG2200	EAL domain
CH63_3554	COG0791	NLP P60 protein
CH63_3555	COG0671	phosphoesterase, PA-phosphatase related
CH63_3556	COG0523	cobalamin synthesis protein
CH63_3558	COG2186	Transcriptional regulator
CH63_3559	COG0246	Mannitol dehydrogenase
CH63_356	COG2879	small protein
CH63_3560	COG1312	Catalyzes the dehydration of D-mannonate
CH63_3564	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_3569	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH63_357	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH63_3571	COG1129	ABC transporter
CH63_3572	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_3573	COG0494	nUDIX hydrolase
CH63_3575	COG1105	Belongs to the carbohydrate kinase PfkB family
CH63_3578	COG3710	Transcriptional regulator
CH63_3581	COG3121	Chaperone
CH63_3582	COG3188	usher protein
CH63_3584	COG2855	membrane
CH63_3585	COG0583	DNA-binding transcription factor activity
CH63_3590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_3592	COG4771	TonB-dependent receptor
CH63_3593	COG0625	glutathione transferase activity
CH63_3599	COG2011	ABC-type metal ion transport system permease component
CH63_3600	COG1686	Belongs to the peptidase S11 family
CH63_3603	COG1349	DNA-binding transcription factor activity
CH63_3604	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH63_3605	COG0671	phosphoesterase, PA-phosphatase related
CH63_3607	COG2985	domain, Protein
CH63_3607	COG0569	domain protein
CH63_3608	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH63_361	COG0023	Translation Initiation Factor
CH63_3611	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH63_3612	COG3842	ATPase activity
CH63_3613	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH63_3614	COG1177	transmembrane transport
CH63_3617	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_3622	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_3623	COG1120	ATPase activity
CH63_3627	COG4160	amino acid transport
CH63_3628	COG4215	(ABC) transporter
CH63_3629	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_3630	COG1126	abc transporter atp-binding protein
CH63_3631	COG1605	Chorismate mutase
CH63_3633	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_3634	COG0702	epimerase
CH63_3635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH63_3636	COG0028	Belongs to the TPP enzyme family
CH63_3637	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_3639	COG2431	L-lysine efflux transmembrane transporter activity
CH63_364	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH63_3640	COG3593	DNA synthesis involved in DNA repair
CH63_3641	COG2990	Protein conserved in bacteria
CH63_3642	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_3644	COG1278	Cold shock
CH63_3646	COG0542	response to heat
CH63_3648	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH63_365	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH63_3651	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH63_3653	COG0492	ferredoxin-NADP+ reductase activity
CH63_3655	COG1674	ftsk spoiiie
CH63_3655	COG3107	peptidoglycan biosynthetic process
CH63_3658	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH63_366	COG0671	phosphoesterase, PA-phosphatase related
CH63_3660	COG2814	Major facilitator Superfamily
CH63_3664	COG2814	Major facilitator Superfamily
CH63_3665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH63_3667	COG1882	Formate acetyltransferase
CH63_3668	COG2116	formate transmembrane transporter activity
CH63_3669	COG1944	ATP diphosphatase activity
CH63_367	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH63_3670	COG0252	asparaginase activity
CH63_3671	COG5295	Hep Hag repeat protein
CH63_3671	COG5295	Hep Hag repeat protein
CH63_3676	COG0539	negative regulation of cytoplasmic translation
CH63_368	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH63_3683	COG5383	Protein conserved in bacteria
CH63_3684	COG1278	Cold shock
CH63_3685	COG2835	tetraacyldisaccharide 4'-kinase activity
CH63_3687	COG3173	Aminoglycoside phosphotransferase
CH63_3688	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH63_3689	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH63_3690	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CH63_3693	COG2989	Protein conserved in bacteria
CH63_3694	COG3108	Peptidase M15
CH63_3695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH63_3696	COG1448	Aminotransferase
CH63_370	COG0583	DNA-binding transcription factor activity
CH63_3700	COG0308	aminopeptidase N
CH63_3703	COG0633	Ferredoxin
CH63_3703	COG3217	Mosc domain protein beta barrel domain protein
CH63_3705	COG0488	(ABC) transporter
CH63_3706	COG2995	paraquat-inducible protein a
CH63_3707	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH63_3707	COG3008	intermembrane lipid transfer
CH63_3708	COG3009	Protein conserved in bacteria
CH63_3709	COG1943	Transposase
CH63_371	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH63_3710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_3713	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_3716	COG1067	ATP-dependent peptidase activity
CH63_3718	COG1943	Transposase
CH63_3719	COG2885	chlorophyll binding
CH63_3719	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH63_3721	COG3070	regulator of competence-specific genes
CH63_3722	COG1289	transmembrane transporter activity
CH63_3723	COG3304	Inner membrane component domain
CH63_3724	COG0210	DNA helicase
CH63_3726	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CH63_3727	COG1832	CoA-binding protein
CH63_3731	COG2920	part of a sulfur-relay system
CH63_3738	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_374	COG0616	signal peptide processing
CH63_3740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH63_3741	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_3742	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_3743	COG3425	synthase
CH63_3745	COG1024	Enoyl-CoA hydratase
CH63_3746	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_3748	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH63_3749	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH63_375	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_377	COG1187	pseudouridine synthase activity
CH63_3776	COG0488	(ABC) transporter
CH63_3778	COG3328	transposase activity
CH63_378	COG0009	L-threonylcarbamoyladenylate synthase
CH63_3780	COG0303	'Molybdopterin
CH63_3782	COG1136	(ABC) transporter
CH63_3788	COG0583	DNA-binding transcription factor activity
CH63_3789	COG0477	Major facilitator Superfamily
CH63_3791	COG2311	Membrane
CH63_3794	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH63_3795	COG2949	membrane
CH63_3798	COG1346	cytolysis
CH63_3800	COG2814	Major facilitator Superfamily
CH63_3805	COG1943	Transposase
CH63_3807	COG0489	protein tyrosine kinase activity
CH63_381	COG0512	Glutamine amidotransferase of anthranilate synthase
CH63_3810	COG2982	Protein involved in outer membrane biogenesis
CH63_3811	COG1253	flavin adenine dinucleotide binding
CH63_3812	COG4114	ferric iron reductase
CH63_3813	COG0076	glutamate decarboxylase activity
CH63_3814	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH63_3817	COG1120	ATPase activity
CH63_3818	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_3819	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_3820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH63_3823	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH63_3824	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH63_3826	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH63_3826	COG0140	phosphoribosyl-ATP diphosphatase activity
CH63_3829	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CH63_383	COG0135	phosphoribosylanthranilate isomerase activity
CH63_383	COG0134	indole-3-glycerol-phosphate synthase activity
CH63_3830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH63_3830	COG0131	Imidazoleglycerol-phosphate dehydratase
CH63_3832	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH63_3834	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_3836	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_3837	COG1129	ABC transporter
CH63_3838	COG1129	ABC transporter
CH63_3839	COG0371	Dehydrogenase
CH63_3841	COG0531	amino acid
CH63_3842	COG2925	Exonuclease
CH63_3845	COG1388	LysM domain
CH63_3845	COG1470	cell adhesion involved in biofilm formation
CH63_3846	COG3328	transposase activity
CH63_3847	COG2271	Major facilitator Superfamily
CH63_3848	COG3011	Protein conserved in bacteria
CH63_3849	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_3851	COG4948	Mandelate Racemase Muconate Lactonizing
CH63_3855	COG0534	Mate efflux family protein
CH63_3859	COG3122	Protein conserved in bacteria
CH63_3864	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH63_3869	COG2223	nitrite transmembrane transporter activity
CH63_387	COG3047	cAMP biosynthetic process
CH63_3870	COG3328	transposase activity
CH63_3880	COG1132	(ABC) transporter
CH63_3882	COG2207	Transcriptional regulator
CH63_3889	COG1113	amino acid transport
CH63_3892	COG1278	Cold shock
CH63_3894	COG2226	methyltransferase
CH63_3896	COG5002	protein histidine kinase activity
CH63_3896	COG5001	Diguanylate cyclase
CH63_3896	COG3447	MASE1 domain protein
CH63_3901	COG3716	PTS system mannose fructose sorbose family IID component
CH63_3902	COG3715	PTS system
CH63_3903	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_3903	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_3904	COG1253	flavin adenine dinucleotide binding
CH63_3905	COG1846	Transcriptional regulator
CH63_3908	COG1012	belongs to the aldehyde dehydrogenase family
CH63_3909	COG3384	dioxygenase
CH63_3911	COG3971	2-oxopent-4-enoate hydratase activity
CH63_3915	COG2368	4-hydroxyphenylacetate
CH63_3916	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH63_3917	COG1760	l-serine dehydratase
CH63_392	COG1607	acyl-coa hydrolase
CH63_3922	COG0513	Belongs to the DEAD box helicase family
CH63_3923	COG3141	response to X-ray
CH63_3926	COG1770	oligopeptidase
CH63_393	COG3328	transposase activity
CH63_3930	COG1528	Iron-storage protein
CH63_3931	COG2372	response to copper ion
CH63_3936	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH63_3937	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH63_394	COG3328	transposase activity
CH63_3942	COG3418	PFAM FlgN family protein
CH63_3943	COG2747	anti-sigma28 factor FlgM
CH63_3945	COG1815	bacterial-type flagellum-dependent cell motility
CH63_3946	COG1558	bacterial-type flagellum-dependent cell motility
CH63_3947	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH63_3948	COG1749	Flagellar hook protein flgE
CH63_395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH63_3950	COG4786	Flagellar basal body rod
CH63_3954	COG1256	bacterial-type flagellum assembly
CH63_3956	COG2390	Transcriptional regulator
CH63_3957	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_3957	COG3347	Dehydrogenase
CH63_3959	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_3961	COG1129	ABC transporter
CH63_3962	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_3963	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_3964	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_3968	COG1987	bacterial-type flagellum assembly
CH63_397	COG2350	Protein conserved in bacteria
CH63_3973	COG1580	Controls the rotational direction of flagella during chemotaxis
CH63_3975	COG2882	bacterial-type flagellum organization
CH63_3976	COG1157	protein secretion by the type III secretion system
CH63_3978	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH63_3980	COG1677	Flagellar hook-basal body complex protein FliE
CH63_3983	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH63_3984	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH63_3986	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH63_3992	COG1191	sigma factor activity
CH63_3994	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CH63_4	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH63_4000	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH63_4000	COG0506	proline dehydrogenase activity
CH63_4000	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH63_4005	COG2837	iron assimilation
CH63_4008	COG1113	amino acid transport
CH63_4012	COG3136	membrane protein required for alginate biosynthesis
CH63_4014	COG2197	response regulator
CH63_4038	COG3328	transposase activity
CH63_4039	COG3328	transposase activity
CH63_404	COG4608	Belongs to the ABC transporter superfamily
CH63_4046	COG0673	inositol 2-dehydrogenase activity
CH63_4048	COG1175	transmembrane transport
CH63_4049	COG0395	ABC-type sugar transport system, permease component
CH63_405	COG0444	Belongs to the ABC transporter superfamily
CH63_4059	COG0402	S-adenosylhomocysteine deaminase activity
CH63_406	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_4062	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH63_4063	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH63_4064	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_407	COG0601	transmembrane transport
CH63_4073	COG3328	transposase activity
CH63_4078	COG0500	methyltransferase
CH63_4087	COG5002	protein histidine kinase activity
CH63_409	COG2095	MarC family integral membrane protein
CH63_4098	COG0012	GTP binding
CH63_410	COG1012	belongs to the aldehyde dehydrogenase family
CH63_410	COG1454	alcohol dehydrogenase
CH63_4101	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH63_4106	COG2890	protein-(glutamine-N5) methyltransferase activity
CH63_4107	COG3094	Invasion gene expression up-regulator, SirB
CH63_4108	COG2912	Transglutaminase-like superfamily
CH63_4110	COG0659	secondary active sulfate transmembrane transporter activity
CH63_4115	COG3833	ABC-type maltose transport systems, permease component
CH63_4116	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH63_4118	COG0584	glycerophosphoryl diester phosphodiesterase
CH63_4119	COG1940	carbohydrate kinase activity
CH63_4122	COG3381	protein complex oligomerization
CH63_4125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH63_4128	COG0728	peptidoglycan biosynthetic process
CH63_4132	COG3102	Protein conserved in bacteria
CH63_4136	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH63_4137	COG1801	Protein of unknown function DUF72
CH63_4139	COG0494	nUDIX hydrolase
CH63_4147	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH63_4150	COG3328	transposase activity
CH63_4157	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH63_4159	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH63_4159	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH63_4166	COG3941	tape measure
CH63_4186	COG1475	DNA binding
CH63_4187	COG1475	DNA binding
CH63_4188	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH63_420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH63_4200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH63_4210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH63_4212	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH63_423	COG5295	Hep Hag repeat protein
CH63_4235	COG1475	DNA binding
CH63_4246	COG3609	addiction module antidote protein, CC2985 family
CH63_4248	COG1475	DNA binding
CH63_4249	COG1192	Involved in chromosome partitioning
CH63_425	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH63_4252	COG2801	Transposase and inactivated derivatives
CH63_4256	COG3177	Filamentation induced by cAMP protein fic
CH63_426	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH63_4261	COG4886	Leucine-rich repeat (LRR) protein
CH63_4265	COG0457	Tetratricopeptide repeat
CH63_4269	COG4789	Type iii secretion
CH63_427	COG0745	RESPONSE REGULATOR receiver
CH63_4278	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH63_4279	COG4790	Type iii secretion
CH63_4280	COG4794	Type iii secretion
CH63_4281	COG4791	protein targeting
CH63_4282	COG4792	protein secretion
CH63_4284	COG2207	Transcriptional regulator
CH63_429	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH63_4294	COG4669	(LipO)protein
CH63_4296	COG1317	bacterial-type flagellum organization
CH63_4297	COG5599	Phosphatase
CH63_4298	COG2963	transposase activity
CH63_4299	COG2801	Transposase and inactivated derivatives
CH63_430	COG0840	transmembrane signaling receptor activity
CH63_4303	COG2801	Transposase and inactivated derivatives
CH63_4305	COG0515	serine threonine protein kinase
CH63_4306	COG0515	serine threonine protein kinase
CH63_431	COG0840	transmembrane signaling receptor activity
CH63_4323	COG2801	Transposase and inactivated derivatives
CH63_4328	COG2801	Transposase and inactivated derivatives
CH63_4333	COG2801	Transposase and inactivated derivatives
CH63_4341	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CH63_435	COG2964	Protein conserved in bacteria
CH63_437	COG0251	oxidation-reduction process
CH63_438	COG2271	Major facilitator Superfamily
CH63_439	COG0835	chemotaxis
CH63_440	COG2198	Histidine kinase
CH63_440	COG0643	Histidine kinase
CH63_441	COG1360	Flagellar Motor Protein
CH63_447	COG1285	pathogenesis
CH63_448	COG0840	transmembrane signaling receptor activity
CH63_449	COG0840	transmembrane signaling receptor activity
CH63_451	COG1278	Cold shock
CH63_453	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_453	COG0604	alcohol dehydrogenase
CH63_453	COG3321	synthase
CH63_455	COG1522	sequence-specific DNA binding
CH63_461	COG1733	regulation of RNA biosynthetic process
CH63_462	COG0702	epimerase
CH63_463	COG0840	transmembrane signaling receptor activity
CH63_466	COG0538	isocitrate dehydrogenase activity
CH63_467	COG1187	pseudouridine synthase activity
CH63_471	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH63_473	COG0745	RESPONSE REGULATOR receiver
CH63_475	COG2850	peptidyl-arginine hydroxylation
CH63_477	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH63_479	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH63_481	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH63_482	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH63_483	COG3134	Outer membrane lipoprotein
CH63_484	COG3328	transposase activity
CH63_487	COG1252	NADH dehydrogenase
CH63_49	COG3328	transposase activity
CH63_490	COG1472	Belongs to the glycosyl hydrolase 3 family
CH63_493	COG5633	Lipoprotein
CH63_494	COG0537	adenosine 5'-monophosphoramidase activity
CH63_495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH63_497	COG1263	PTS System
CH63_497	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_498	COG0084	hydrolase, TatD family'
CH63_499	COG0470	DNA polymerase III
CH63_501	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH63_502	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH63_503	COG1943	Transposase
CH63_504	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_506	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH63_511	COG1399	metal-binding, possibly nucleic acid-binding protein
CH63_513	COG0564	pseudouridine synthase activity
CH63_514	COG1530	ribonuclease E activity
CH63_515	COG3328	transposase activity
CH63_516	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH63_519	COG3328	transposase activity
CH63_523	COG0628	permease
CH63_527	COG2771	luxR family
CH63_528	COG3916	Acyl-homoserine-lactone synthase
CH63_529	COG0583	DNA-binding transcription factor activity
CH63_531	COG0477	Major facilitator Superfamily
CH63_534	COG0667	Aldo Keto reductase
CH63_539	COG1203	CRISPR-associated helicase, Cas3
CH63_540	COG1518	maintenance of DNA repeat elements
CH63_541	COG0668	transmembrane transport
CH63_545	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH63_546	COG0395	ABC-type sugar transport system, permease component
CH63_549	COG1609	Transcriptional regulator
CH63_551	COG3842	ATPase activity
CH63_553	COG3210	domain, Protein
CH63_556	COG3210	domain, Protein
CH63_559	COG3210	domain, Protein
CH63_560	COG3210	domain, Protein
CH63_561	COG2831	hemolysin activation secretion protein
CH63_562	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH63_566	COG0473	3-isopropylmalate dehydrogenase activity
CH63_567	COG0583	DNA-binding transcription factor activity
CH63_568	COG1609	Transcriptional regulator
CH63_569	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_570	COG1129	ABC transporter
CH63_571	COG1879	ABC-type sugar transport system periplasmic component
CH63_572	COG1063	alcohol dehydrogenase
CH63_576	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH63_582	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_583	COG0765	amino acid transport
CH63_584	COG1126	abc transporter atp-binding protein
CH63_591	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH63_594	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH63_598	COG1169	isochorismate synthase
CH63_6	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH63_600	COG4575	ribosome binding
CH63_602	COG0129	dihydroxy-acid dehydratase activity
CH63_605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH63_606	COG1609	Transcriptional regulator
CH63_608	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_609	COG3265	gluconokinase activity
CH63_610	COG2731	YhcH YjgK YiaL family protein
CH63_613	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH63_614	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH63_616	COG0839	Belongs to the complex I subunit 6 family
CH63_619	COG1034	ATP synthesis coupled electron transport
CH63_621	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CH63_623	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH63_625	COG0583	DNA-binding transcription factor activity
CH63_626	COG0436	Aminotransferase
CH63_628	COG0471	metal ion transport
CH63_628	COG0490	domain, Protein
CH63_629	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_633	COG0857	belongs to the CobB CobQ family
CH63_633	COG0280	phosphate acetyltransferase
CH63_634	COG1609	Transcriptional regulator
CH63_637	COG3328	transposase activity
CH63_638	COG3037	sugar-specific permease SgaT UlaA
CH63_639	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH63_640	COG0622	Phosphoesterase
CH63_642	COG1090	epimerase
CH63_643	COG4598	ABC transporter
CH63_644	COG4160	amino acid transport
CH63_645	COG4215	(ABC) transporter
CH63_646	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_647	COG0163	prenyltransferase activity
CH63_648	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH63_649	COG1286	toxin biosynthetic process
CH63_650	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH63_651	COG0285	dihydrofolate synthase activity
CH63_653	COG0586	Pfam SNARE associated Golgi protein
CH63_655	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH63_658	COG0697	spore germination
CH63_661	COG1794	racemase activity, acting on amino acids and derivatives
CH63_662	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_665	COG3101	peptidyl-lysine hydroxylation
CH63_666	COG0730	response to heat
CH63_669	COG2890	protein-(glutamine-N5) methyltransferase activity
CH63_671	COG2062	phosphohistidine phosphatase, SixA
CH63_674	COG3691	Protein conserved in bacteria
CH63_677	COG4235	cytochrome complex assembly
CH63_677	COG3088	subunit of a heme lyase
CH63_679	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH63_680	COG1138	Cytochrome C-type biogenesis protein
CH63_682	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH63_683	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH63_684	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH63_688	COG1704	LemA family
CH63_690	COG2824	Alkylphosphonate utilization operon protein PhnA
CH63_696	COG3501	Rhs element vgr protein
CH63_7	COG0739	heme binding
CH63_709	COG3188	usher protein
CH63_710	COG3328	transposase activity
CH63_711	COG3188	usher protein
CH63_712	COG3121	Chaperone
CH63_724	COG2951	lytic endotransglycosylase activity
CH63_732	COG0243	molybdopterin cofactor binding
CH63_733	COG0437	4 iron, 4 sulfur cluster binding
CH63_734	COG3302	dmso reductase anchor subunit
CH63_735	COG3381	protein complex oligomerization
CH63_741	COG3038	cytochrome b561
CH63_742	COG0436	Aminotransferase
CH63_747	COG0667	Aldo Keto reductase
CH63_750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH63_755	COG1943	Transposase
CH63_761	COG3530	Putative quorum-sensing-regulated virulence factor
CH63_764	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH63_765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH63_766	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_768	COG2190	(PTS) system
CH63_774	COG2205	protein histidine kinase activity
CH63_775	COG0745	RESPONSE REGULATOR receiver
CH63_776	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_779	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH63_781	COG0006	proline dipeptidase activity
CH63_783	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH63_785	COG5002	protein histidine kinase activity
CH63_785	COG3850	Histidine kinase
CH63_786	COG0745	RESPONSE REGULATOR receiver
CH63_789	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH63_790	COG4208	sulfate ABC transporter
CH63_791	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH63_792	COG4150	thiosulfate binding
CH63_793	COG4150	thiosulfate binding
CH63_795	COG1737	Transcriptional regulator
CH63_796	COG2731	YhcH YjgK YiaL family protein
CH63_798	COG4886	Leucine-rich repeat (LRR) protein
CH63_8	COG1560	Kdo2-lipid A biosynthetic process
CH63_800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH63_801	COG2837	iron assimilation
CH63_803	COG3111	PFAM Bacterial OB fold (BOF) protein
CH63_81	COG3328	transposase activity
CH63_812	COG3005	denitrification pathway
CH63_813	COG3043	anaerobic respiration
CH63_815	COG3062	negative regulation of establishment of protein localization
CH63_816	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_816	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_817	COG2197	response regulator
CH63_819	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_821	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_823	COG1988	membrane-bound metal-dependent
CH63_824	COG0641	radical SAM
CH63_825	COG3119	arylsulfatase activity
CH63_826	COG3842	ATPase activity
CH63_827	COG1175	transmembrane transport
CH63_828	COG1840	ABC-type Fe3 transport system, periplasmic component
CH63_83	COG1104	cysteine desulfurase activity
CH63_830	COG1393	Belongs to the ArsC family
CH63_832	COG1876	peptidase activity
CH63_836	COG2321	neutral zinc metallopeptidase
CH63_838	COG1943	Transposase
CH63_839	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH63_841	COG2716	regulation of RNA biosynthetic process
CH63_842	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH63_845	COG0628	permease
CH63_846	COG4783	chaperone-mediated protein folding
CH63_847	COG1393	Belongs to the ArsC family
CH63_849	COG1943	Transposase
CH63_852	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH63_853	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH63_858	COG0581	inorganic phosphate transmembrane transporter activity
CH63_861	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH63_862	COG0248	Ppx GppA phosphatase
CH63_863	COG2239	Acts as a magnesium transporter
CH63_864	COG0443	Heat shock 70 kDa protein
CH63_865	COG1177	transmembrane transport
CH63_866	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH63_868	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH63_870	COG3842	ATPase activity
CH63_875	COG2205	protein histidine kinase activity
CH63_876	COG0745	RESPONSE REGULATOR receiver
CH63_877	COG3422	double-strand break repair
CH63_884	COG0351	phosphomethylpyrimidine kinase
CH63_887	COG3328	transposase activity
CH63_89	COG2719	SpoVR family
CH63_894	COG0513	Belongs to the DEAD box helicase family
CH63_895	COG1309	transcriptional regulator
CH63_897	COG1131	(ABC) transporter
CH63_898	COG0842	Transport permease protein
CH63_899	COG0842	Transport permease protein
CH63_9	COG0469	pyruvate kinase activity
CH63_901	COG1902	pentaerythritol trinitrate reductase activity
CH63_906	COG2211	Major facilitator Superfamily
CH63_908	COG2211	Major facilitator Superfamily
CH63_909	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH63_91	COG2814	Major facilitator Superfamily
CH63_911	COG0583	DNA-binding transcription factor activity
CH63_912	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH63_916	COG1943	Transposase
CH63_917	COG0670	Belongs to the BI1 family
CH63_918	COG0314	molybdopterin synthase activity
CH63_919	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH63_921	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH63_923	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH63_924	COG4628	conserved protein (DUF2132)
CH63_925	COG0556	nucleotide-excision repair
CH63_927	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH63_928	COG2226	methyltransferase
CH63_93	COG0583	DNA-binding transcription factor activity
CH63_933	COG0561	phosphatase activity
CH63_935	COG4149	molybdate abc transporter
CH63_936	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH63_938	COG2005	Transcriptional regulator
CH63_938	COG3585	molybdate ion transport
CH63_939	COG1119	ATPase activity
CH63_942	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH63_943	COG1085	galactose-1-phosphate uridylyltransferase
CH63_946	COG2017	converts alpha-aldose to the beta-anomer
CH63_949	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH63_951	COG1230	cation diffusion facilitator family transporter
CH63_957	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH63_958	COG2885	chlorophyll binding
CH63_96	COG2766	serine protein kinase
CH63_960	COG3064	Membrane
CH63_960	COG3064	Membrane
CH63_961	COG0848	biopolymer transport protein
CH63_962	COG0811	peptide transport
CH63_963	COG0824	Thioesterase
CH63_964	COG3790	cyd operon protein YbgE
CH63_965	COG4890	Cyd operon protein YbgT
CH63_966	COG1294	oxidase, subunit
CH63_967	COG1271	oxidase subunit
CH63_968	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH63_97	COG3713	MltA-interacting MipA family protein
CH63_970	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH63_971	COG0567	Dehydrogenase, E1 component
CH63_973	COG1053	succinate dehydrogenase
CH63_974	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH63_975	COG2009	succinate dehydrogenase
CH63_978	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH63_979	COG0497	DNA recombination
CH63_980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH63_982	COG2867	negative regulation of translational initiation
CH63_985	COG0582	viral genome integration into host DNA
CH63_995	COG3657	addiction module killer protein