locus-tag	class	description
YPDSF_0002	COG0592	DNA-directed DNA polymerase activity
YPDSF_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YPDSF_0004	COG0187	DNA topoisomerase II activity
YPDSF_0005	COG0561	phosphatase activity
YPDSF_0006	COG2801	Transposase and inactivated derivatives
YPDSF_0007	COG2423	ornithine cyclodeaminase activity
YPDSF_0008	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPDSF_0009	COG0823	Involved in the tonB-independent uptake of proteins
YPDSF_0010	COG0823	Involved in the tonB-independent uptake of proteins
YPDSF_0011	COG5645	(Lipo)protein
YPDSF_0015	COG3977	Valine--pyruvate aminotransferase
YPDSF_0016	COG0366	Alpha amylase catalytic
YPDSF_0019	COG2885	chlorophyll binding
YPDSF_0021	COG2818	Glycosylase
YPDSF_0025	COG2213	PTS system mannitol-specific
YPDSF_0025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_0027	COG3722	fumarate hydratase activity
YPDSF_0032	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPDSF_0034	COG0243	molybdopterin cofactor binding
YPDSF_0034	COG3383	formate dehydrogenase (NAD+) activity
YPDSF_0035	COG3383	formate dehydrogenase (NAD+) activity
YPDSF_0035	COG0243	molybdopterin cofactor binding
YPDSF_0036	COG0437	4 iron, 4 sulfur cluster binding
YPDSF_0037	COG2864	formate dehydrogenase
YPDSF_0040	COG3276	selenocysteine insertion sequence binding
YPDSF_0043	COG3328	transposase activity
YPDSF_0047	COG2801	Transposase and inactivated derivatives
YPDSF_0048	COG1349	DNA-binding transcription factor activity
YPDSF_0052	COG0058	SHG alpha-glucan phosphorylase activity
YPDSF_0053	COG1640	4-alpha-glucanotransferase
YPDSF_0060	COG1918	ferrous iron import across plasma membrane
YPDSF_0061	COG2183	response to ionizing radiation
YPDSF_0062	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPDSF_0063	COG0745	RESPONSE REGULATOR receiver
YPDSF_0067	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPDSF_0068	COG1011	Hydrolase
YPDSF_0070	COG0494	nUDIX hydrolase
YPDSF_0071	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPDSF_0077	COG4796	Type ii and iii secretion system protein
YPDSF_0082	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPDSF_0083	COG0546	phosphoglycolate phosphatase activity
YPDSF_0084	COG0180	Tryptophanyl-tRNA synthetase
YPDSF_0087	COG2146	nitrite reductase [NAD(P)H] activity
YPDSF_0088	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPDSF_0089	COG0402	S-adenosylhomocysteine deaminase activity
YPDSF_0095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPDSF_0096	COG0433	COG0433 Predicted ATPase
YPDSF_0099	COG1289	transmembrane transporter activity
YPDSF_0101	COG1765	OsmC-like protein
YPDSF_0103	COG3954	Phosphoribulokinase
YPDSF_0105	COG0429	hydrolase of the alpha beta-hydrolase fold
YPDSF_0107	COG4521	taurine ABC transporter
YPDSF_0109	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPDSF_0110	COG2175	clavaminate synthase activity
YPDSF_0113	COG1216	Glycosyl transferase, family 2
YPDSF_0114	COG0488	(ABC) transporter
YPDSF_0117	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPDSF_0118	COG1047	Peptidyl-prolyl cis-trans
YPDSF_0120	COG0545	Peptidyl-prolyl cis-trans isomerase
YPDSF_0121	COG2964	Protein conserved in bacteria
YPDSF_0126	COG0049	tRNA binding
YPDSF_0129	COG1943	Transposase
YPDSF_0132	COG0051	transcription antitermination factor activity, RNA binding
YPDSF_0137	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPDSF_0139	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPDSF_0140	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPDSF_0142	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPDSF_0143	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPDSF_0152	COG0201	protein transport
YPDSF_0155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPDSF_0158	COG0789	Transcriptional regulator
YPDSF_0159	COG3036	rescue of stalled ribosome
YPDSF_0161	COG0569	domain protein
YPDSF_0165	COG0758	DNA mediated transformation
YPDSF_0167	COG0551	DNA topoisomerase type I activity
YPDSF_0170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPDSF_0173	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPDSF_0174	COG2224	Isocitrate lyase
YPDSF_0176	COG1414	Transcriptional regulator
YPDSF_0181	COG0527	aspartate kinase activity
YPDSF_0184	COG3833	ABC-type maltose transport systems, permease component
YPDSF_0185	COG1175	transmembrane transport
YPDSF_0197	COG2801	Transposase and inactivated derivatives
YPDSF_0212	COG3501	Rhs element vgr protein
YPDSF_0215	COG3209	COG3209 Rhs family protein
YPDSF_0220	COG3501	Rhs element vgr protein
YPDSF_0222	COG3209	COG3209 Rhs family protein
YPDSF_0225	COG0673	inositol 2-dehydrogenase activity
YPDSF_0226	COG1917	Cupin 2, conserved barrel domain protein
YPDSF_0226	COG2207	Transcriptional regulator
YPDSF_0227	COG1869	D-ribose catabolic process
YPDSF_0228	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_0230	COG0431	NADPH-dependent FMN reductase
YPDSF_0231	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPDSF_0233	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPDSF_0235	COG3077	Addiction module antitoxin, RelB DinJ family
YPDSF_0236	COG2252	PERMEase
YPDSF_0237	COG0025	NhaP-type Na H and K H
YPDSF_0239	COG1560	Kdo2-lipid A biosynthetic process
YPDSF_0241	COG1129	ABC transporter
YPDSF_0242	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_0244	COG1069	ribulokinase activity
YPDSF_0246	COG0625	glutathione transferase activity
YPDSF_0249	COG1943	Transposase
YPDSF_0250	COG1278	Cold shock
YPDSF_0251	COG1278	Cold shock
YPDSF_0253	COG3133	Outer membrane lipoprotein
YPDSF_0254	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPDSF_0256	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPDSF_0260	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPDSF_0261	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPDSF_0263	COG4145	pantothenate transmembrane transporter activity
YPDSF_0264	COG3924	membrane
YPDSF_0265	COG0439	Biotin carboxylase
YPDSF_0266	COG0511	ligase activity, forming carbon-carbon bonds
YPDSF_0269	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YPDSF_0270	COG0604	alcohol dehydrogenase
YPDSF_0271	COG2199	diguanylate cyclase activity
YPDSF_0271	COG2200	EAL domain
YPDSF_0272	COG1077	Cell shape determining protein MreB Mrl
YPDSF_0273	COG1792	Involved in formation and maintenance of cell shape
YPDSF_0274	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPDSF_0276	COG1530	ribonuclease E activity
YPDSF_0277	COG3164	Protein of unknown function
YPDSF_0278	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPDSF_0279	COG0312	modulator of DNA gyrase
YPDSF_0290	COG0583	DNA-binding transcription factor activity
YPDSF_0294	COG1012	belongs to the aldehyde dehydrogenase family
YPDSF_0297	COG2732	(Barnase) inhibitor
YPDSF_0299	COG0312	modulator of DNA gyrase
YPDSF_0301	COG3783	Cytochrome b(562)
YPDSF_0302	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPDSF_0303	COG0366	Alpha amylase catalytic
YPDSF_0304	COG1263	PTS System
YPDSF_0304	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_0305	COG1609	Transcriptional regulator
YPDSF_0310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_0312	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_0313	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPDSF_0315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPDSF_0316	COG1137	ATPase activity
YPDSF_0317	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPDSF_0318	COG3117	lipopolysaccharide transmembrane transporter activity
YPDSF_0319	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPDSF_0320	COG0517	IMP dehydrogenase activity
YPDSF_0320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPDSF_0321	COG0530	calcium, potassium:sodium antiporter activity
YPDSF_0322	COG1127	ABC transporter
YPDSF_0323	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPDSF_0324	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPDSF_0325	COG2854	intermembrane phospholipid transfer
YPDSF_0326	COG3113	response to antibiotic
YPDSF_0327	COG5007	Belongs to the BolA IbaG family
YPDSF_0329	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPDSF_0330	COG1943	Transposase
YPDSF_0331	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPDSF_0332	COG3105	Protein conserved in bacteria
YPDSF_0333	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPDSF_0336	COG0625	glutathione transferase activity
YPDSF_0337	COG2969	positive regulation of protein catabolic process
YPDSF_0339	COG0493	'glutamate synthase
YPDSF_0340	COG0067	glutamate synthase
YPDSF_0340	COG0070	glutamate synthase
YPDSF_0340	COG0069	glutamate synthase activity
YPDSF_0341	COG1242	4 iron, 4 sulfur cluster binding
YPDSF_0342	COG5002	protein histidine kinase activity
YPDSF_0342	COG2198	Histidine kinase
YPDSF_0342	COG0784	Response regulator, receiver
YPDSF_0346	COG2823	Periplasmic or secreted lipoprotein
YPDSF_0350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPDSF_0351	COG1741	Belongs to the pirin family
YPDSF_0352	COG0583	DNA-binding transcription factor activity
YPDSF_0353	COG0435	Glutathione S-transferase
YPDSF_0354	COG2259	Doxx family
YPDSF_0356	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPDSF_0357	COG4575	ribosome binding
YPDSF_0361	COG0586	Pfam SNARE associated Golgi protein
YPDSF_0367	COG0246	Mannitol dehydrogenase
YPDSF_0368	COG2721	sulfolactate sulfo-lyase activity
YPDSF_0370	COG1943	Transposase
YPDSF_0372	COG0673	inositol 2-dehydrogenase activity
YPDSF_0373	COG1451	nucleotide metabolic process
YPDSF_0376	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPDSF_0376	COG1902	pentaerythritol trinitrate reductase activity
YPDSF_0377	COG3247	response to pH
YPDSF_0384	COG4245	von Willebrand factor, type A
YPDSF_0385	COG2831	hemolysin activation secretion protein
YPDSF_0386	COG3210	domain, Protein
YPDSF_0387	COG3210	domain, Protein
YPDSF_0388	COG3210	domain, Protein
YPDSF_0389	COG3210	domain, Protein
YPDSF_0390	COG3210	domain, Protein
YPDSF_0394	COG3842	ATPase activity
YPDSF_0395	COG3459	Glycosyltransferase 36 associated
YPDSF_0396	COG1609	Transcriptional regulator
YPDSF_0397	COG1653	transport
YPDSF_0399	COG0395	ABC-type sugar transport system, permease component
YPDSF_0403	COG1289	transmembrane transporter activity
YPDSF_0412	COG0251	oxidation-reduction process
YPDSF_0427	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPDSF_0428	COG0358	DNA primase activity
YPDSF_0432	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPDSF_0435	COG4991	sh3 domain protein
YPDSF_0436	COG3025	triphosphatase activity
YPDSF_0439	COG0531	amino acid
YPDSF_0442	COG3384	dioxygenase
YPDSF_0443	COG0754	glutathionylspermidine amidase activity
YPDSF_0445	COG1538	Outer membrane efflux protein
YPDSF_0446	COG0494	nUDIX hydrolase
YPDSF_0447	COG3151	Protein conserved in bacteria
YPDSF_0448	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPDSF_0449	COG3150	esterase
YPDSF_0450	COG0187	DNA topoisomerase II activity
YPDSF_0451	COG0583	DNA-binding transcription factor activity
YPDSF_0452	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPDSF_0454	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPDSF_0455	COG0204	Acyl-transferase
YPDSF_0457	COG2132	Multicopper oxidase
YPDSF_0460	COG0656	L-ascorbic acid biosynthetic process
YPDSF_0462	COG1979	alcohol dehydrogenase
YPDSF_0463	COG2207	Transcriptional regulator
YPDSF_0464	COG0586	Pfam SNARE associated Golgi protein
YPDSF_0465	COG0626	cystathionine gamma-synthase activity
YPDSF_0466	COG0811	peptide transport
YPDSF_0467	COG0848	biopolymer transport protein
YPDSF_0476	COG4964	Belongs to the GSP D family
YPDSF_0477	COG4964	Belongs to the GSP D family
YPDSF_0485	COG4592	Periplasmic binding protein
YPDSF_0490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPDSF_0491	COG1684	flagellar biosynthetic protein fliR
YPDSF_0492	COG1987	bacterial-type flagellum assembly
YPDSF_0496	COG2204	response regulator
YPDSF_0505	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPDSF_0506	COG1815	bacterial-type flagellum-dependent cell motility
YPDSF_0507	COG1558	bacterial-type flagellum-dependent cell motility
YPDSF_0508	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPDSF_0509	COG1749	Flagellar hook protein flgE
YPDSF_0510	COG4787	bacterial-type flagellum-dependent cell motility
YPDSF_0511	COG4786	Flagellar basal body rod
YPDSF_0512	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YPDSF_0513	COG1706	bacterial-type flagellum-dependent cell motility
YPDSF_0515	COG1256	bacterial-type flagellum assembly
YPDSF_0519	COG3710	Transcriptional regulator
YPDSF_0522	COG2801	Transposase and inactivated derivatives
YPDSF_0523	COG2211	Major facilitator Superfamily
YPDSF_0533	COG2771	luxR family
YPDSF_0534	COG3916	Acyl-homoserine-lactone synthase
YPDSF_0550	COG1662	PFAM IS1 transposase
YPDSF_0554	COG1982	Orn Lys Arg decarboxylase major
YPDSF_0555	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_0556	COG1129	ABC transporter
YPDSF_0557	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_0558	COG4774	siderophore transport
YPDSF_0562	COG1194	a g-specific adenine glycosylase
YPDSF_0564	COG3171	Protein conserved in bacteria
YPDSF_0565	COG2066	Belongs to the glutaminase family
YPDSF_0568	COG1073	alpha beta
YPDSF_0568	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPDSF_0568	COG3064	Membrane
YPDSF_0569	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPDSF_0570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPDSF_0572	COG0762	integral membrane protein
YPDSF_0573	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPDSF_0574	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPDSF_0575	COG2805	Type II/IV secretion system protein
YPDSF_0577	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPDSF_0580	COG0189	ligase activity
YPDSF_0581	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPDSF_0583	COG2356	endonuclease I
YPDSF_0586	COG1166	arginine decarboxylase activity
YPDSF_0588	COG0501	Belongs to the peptidase M48B family
YPDSF_0589	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPDSF_0593	COG0191	fructose-bisphosphate aldolase activity
YPDSF_0598	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPDSF_0599	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPDSF_0600	COG1943	Transposase
YPDSF_0601	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPDSF_0604	COG0006	proline dipeptidase activity
YPDSF_0605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPDSF_0606	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPDSF_0615	COG1272	protein, Hemolysin III
YPDSF_0618	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YPDSF_0620	COG0745	RESPONSE REGULATOR receiver
YPDSF_0621	COG2205	protein histidine kinase activity
YPDSF_0622	COG4452	Inner membrane protein CreD
YPDSF_0623	COG0716	FMN binding
YPDSF_0624	COG4974	Belongs to the 'phage' integrase family
YPDSF_0625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPDSF_0626	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPDSF_0629	COG0582	viral genome integration into host DNA
YPDSF_0634	COG2944	sequence-specific DNA binding
YPDSF_0649	COG1695	Transcriptional regulator
YPDSF_0650	COG0791	NLP P60 protein
YPDSF_0652	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_0653	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_0654	COG1129	ABC transporter
YPDSF_0656	COG2182	Extracellular solute-binding protein
YPDSF_0658	COG1175	transmembrane transport
YPDSF_0659	COG3833	ABC-type maltose transport systems, permease component
YPDSF_0660	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPDSF_0667	COG2271	Major facilitator Superfamily
YPDSF_0670	COG0191	fructose-bisphosphate aldolase activity
YPDSF_0672	COG3119	arylsulfatase activity
YPDSF_0673	COG0641	radical SAM
YPDSF_0675	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_0677	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_0678	COG3716	PTS system mannose fructose sorbose family IID component
YPDSF_0679	COG3715	PTS system
YPDSF_0680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_0681	COG2222	sugar isomerase
YPDSF_0683	COG1349	DNA-binding transcription factor activity
YPDSF_0684	COG3119	arylsulfatase activity
YPDSF_0685	COG1943	Transposase
YPDSF_0692	COG0288	reversible hydration of carbon dioxide
YPDSF_0705	COG3328	transposase activity
YPDSF_0706	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_0710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPDSF_0711	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPDSF_0712	COG1121	(ABC) transporter
YPDSF_0713	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPDSF_0716	COG4249	Peptidase C14 caspase catalytic subunit p20
YPDSF_0721	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YPDSF_0722	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YPDSF_0722	COG0072	phenylalanine-tRNA ligase activity
YPDSF_0723	COG0776	regulation of translation
YPDSF_0726	COG0386	Belongs to the glutathione peroxidase family
YPDSF_0727	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YPDSF_0735	COG0791	NLP P60 protein
YPDSF_0740	COG0574	Belongs to the PEP-utilizing enzyme family
YPDSF_0740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPDSF_0741	COG0628	permease
YPDSF_0742	COG0277	FAD linked oxidase domain protein
YPDSF_0742	COG0247	lactate metabolic process
YPDSF_0743	COG2050	protein possibly involved in aromatic compounds catabolism
YPDSF_0744	COG0316	Belongs to the HesB IscA family
YPDSF_0745	COG0719	Fe-S assembly protein
YPDSF_0746	COG0396	ATPase activity
YPDSF_0747	COG0719	Fe-S assembly protein
YPDSF_0750	COG1376	ErfK ybiS ycfS ynhG family protein
YPDSF_0750	COG1388	LysM domain
YPDSF_0756	COG0307	riboflavin synthase, alpha
YPDSF_0757	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPDSF_0758	COG2814	Major facilitator Superfamily
YPDSF_0759	COG0583	DNA-binding transcription factor activity
YPDSF_0761	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPDSF_0762	COG0791	NLP P60 protein
YPDSF_0763	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPDSF_0765	COG0346	lactoylglutathione lyase activity
YPDSF_0767	COG1902	pentaerythritol trinitrate reductase activity
YPDSF_0768	COG1309	transcriptional regulator
YPDSF_0769	COG2194	sulfuric ester hydrolase activity
YPDSF_0770	COG3313	Fe-S protein
YPDSF_0771	COG4989	oxidoreductase activity
YPDSF_0773	COG3133	Outer membrane lipoprotein
YPDSF_0775	COG3895	Periplasmic Protein
YPDSF_0779	COG0625	glutathione transferase activity
YPDSF_0782	COG3104	oligopeptide transport
YPDSF_0783	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPDSF_0783	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPDSF_0784	COG4172	Belongs to the ABC transporter superfamily
YPDSF_0786	COG4171	peptide transport system, permease
YPDSF_0787	COG4168	peptide transport system, permease
YPDSF_0788	COG4166	transmembrane transport
YPDSF_0790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPDSF_0791	COG1842	Phage shock protein A
YPDSF_0793	COG1983	PspC domain protein
YPDSF_0795	COG3106	COG3106 Predicted ATPase
YPDSF_0803	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPDSF_0804	COG4948	Mandelate Racemase Muconate Lactonizing
YPDSF_0805	COG2866	Carboxypeptidase
YPDSF_0806	COG4166	transmembrane transport
YPDSF_0810	COG0657	acetylesterase activity
YPDSF_0810	COG2755	lipolytic protein G-D-S-L family
YPDSF_0812	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPDSF_0812	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPDSF_0812	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPDSF_0812	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPDSF_0814	COG1285	pathogenesis
YPDSF_0815	COG3042	response to heat
YPDSF_0816	COG3187	Heat shock protein
YPDSF_0817	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPDSF_0818	COG2911	Protein conserved in bacteria
YPDSF_0820	COG3784	Protein of unknown function (DUF1318)
YPDSF_0821	COG0246	Mannitol dehydrogenase
YPDSF_0822	COG2390	Transcriptional regulator
YPDSF_0824	COG1643	Atp-dependent helicase
YPDSF_0826	COG3591	Belongs to the peptidase S1B family
YPDSF_0828	COG3038	cytochrome b561
YPDSF_0834	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPDSF_0835	COG2205	protein histidine kinase activity
YPDSF_0836	COG0745	RESPONSE REGULATOR receiver
YPDSF_0838	COG0531	amino acid
YPDSF_0840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPDSF_0841	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPDSF_0842	COG0589	response to stress
YPDSF_0843	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPDSF_0844	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPDSF_0847	COG1011	Hydrolase
YPDSF_0848	COG0440	acetolactate synthase activity
YPDSF_0849	COG0028	Belongs to the TPP enzyme family
YPDSF_0855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPDSF_0857	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPDSF_0858	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPDSF_0861	COG1609	Transcriptional regulator
YPDSF_0863	COG0038	chloride channel
YPDSF_0864	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPDSF_0865	COG1940	carbohydrate kinase activity
YPDSF_0866	COG0583	DNA-binding transcription factor activity
YPDSF_0867	COG2814	Major facilitator Superfamily
YPDSF_0869	COG0114	fumarate hydratase activity
YPDSF_0871	COG5339	Protein conserved in bacteria
YPDSF_0873	COG0385	Bile acid
YPDSF_0874	COG0673	inositol 2-dehydrogenase activity
YPDSF_0879	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_0882	COG2274	protein secretion by the type I secretion system
YPDSF_0883	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_0885	COG2274	protein secretion by the type I secretion system
YPDSF_0892	COG3708	Transcriptional regulator
YPDSF_0892	COG2207	Transcriptional regulator
YPDSF_0893	COG4658	electron transport chain
YPDSF_0894	COG4659	FMN binding
YPDSF_0896	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPDSF_0897	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_0898	COG2271	Major facilitator Superfamily
YPDSF_0900	COG1966	Carbon starvation protein
YPDSF_0901	COG2879	small protein
YPDSF_0902	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPDSF_0906	COG0023	Translation Initiation Factor
YPDSF_0909	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPDSF_0910	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPDSF_0911	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_0912	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YPDSF_0913	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPDSF_0915	COG0583	DNA-binding transcription factor activity
YPDSF_0916	COG1943	Transposase
YPDSF_0917	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPDSF_0919	COG0616	signal peptide processing
YPDSF_0920	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_0922	COG1187	pseudouridine synthase activity
YPDSF_0923	COG0009	L-threonylcarbamoyladenylate synthase
YPDSF_0926	COG0512	Glutamine amidotransferase of anthranilate synthase
YPDSF_0928	COG0135	phosphoribosylanthranilate isomerase activity
YPDSF_0928	COG0134	indole-3-glycerol-phosphate synthase activity
YPDSF_0933	COG3047	cAMP biosynthetic process
YPDSF_0939	COG1607	acyl-coa hydrolase
YPDSF_0940	COG3328	transposase activity
YPDSF_0941	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPDSF_0942	COG2350	Protein conserved in bacteria
YPDSF_0950	COG4608	Belongs to the ABC transporter superfamily
YPDSF_0951	COG0444	Belongs to the ABC transporter superfamily
YPDSF_0952	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPDSF_0953	COG0601	transmembrane transport
YPDSF_0955	COG2095	MarC family integral membrane protein
YPDSF_0956	COG1454	alcohol dehydrogenase
YPDSF_0956	COG1012	belongs to the aldehyde dehydrogenase family
YPDSF_0957	COG1435	thymidine kinase activity
YPDSF_0959	COG3328	transposase activity
YPDSF_0961	COG0745	RESPONSE REGULATOR receiver
YPDSF_0963	COG0788	formyltetrahydrofolate deformylase activity
YPDSF_0964	COG3328	transposase activity
YPDSF_0965	COG0583	DNA-binding transcription factor activity
YPDSF_0966	COG0708	Exodeoxyribonuclease III
YPDSF_0967	COG0494	nUDIX hydrolase
YPDSF_0969	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPDSF_0970	COG0709	Synthesizes selenophosphate from selenide and ATP
YPDSF_0971	COG0778	Nitroreductase
YPDSF_0972	COG0616	signal peptide processing
YPDSF_0973	COG0252	asparaginase activity
YPDSF_0974	COG1335	isochorismatase
YPDSF_0975	COG3139	Protein of unknown function (DUF1315)
YPDSF_0979	COG3713	MltA-interacting MipA family protein
YPDSF_0980	COG2766	serine protein kinase
YPDSF_0983	COG0583	DNA-binding transcription factor activity
YPDSF_0985	COG2814	Major facilitator Superfamily
YPDSF_0987	COG2719	SpoVR family
YPDSF_0993	COG1104	cysteine desulfurase activity
YPDSF_1008	COG1943	Transposase
YPDSF_1038	COG0582	viral genome integration into host DNA
YPDSF_1040	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPDSF_1041	COG2951	lytic endotransglycosylase activity
YPDSF_1044	COG2894	cell division
YPDSF_1045	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPDSF_1046	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPDSF_1047	COG0318	PFAM AMP-dependent synthetase and ligase
YPDSF_1051	COG1199	ATP-dependent helicase activity
YPDSF_1052	COG0251	oxidation-reduction process
YPDSF_1055	COG0800	Aldolase
YPDSF_1056	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPDSF_1057	COG1737	Transcriptional regulator
YPDSF_1058	COG0469	pyruvate kinase activity
YPDSF_1059	COG1560	Kdo2-lipid A biosynthetic process
YPDSF_1060	COG0739	heme binding
YPDSF_1061	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPDSF_1063	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPDSF_1068	COG0494	nUDIX hydrolase
YPDSF_1070	COG1801	Protein of unknown function DUF72
YPDSF_1071	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPDSF_1075	COG3102	Protein conserved in bacteria
YPDSF_1080	COG0728	peptidoglycan biosynthetic process
YPDSF_1082	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPDSF_1085	COG3381	protein complex oligomerization
YPDSF_1087	COG1940	carbohydrate kinase activity
YPDSF_1088	COG0584	glycerophosphoryl diester phosphodiesterase
YPDSF_1089	COG3842	ATPase activity
YPDSF_1092	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPDSF_1093	COG3833	ABC-type maltose transport systems, permease component
YPDSF_1096	COG0659	secondary active sulfate transmembrane transporter activity
YPDSF_1098	COG2912	Transglutaminase-like superfamily
YPDSF_1099	COG3094	Invasion gene expression up-regulator, SirB
YPDSF_1100	COG2890	protein-(glutamine-N5) methyltransferase activity
YPDSF_1106	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPDSF_1109	COG0012	GTP binding
YPDSF_1119	COG0745	RESPONSE REGULATOR receiver
YPDSF_1123	COG5002	protein histidine kinase activity
YPDSF_1131	COG0500	methyltransferase
YPDSF_1135	COG3328	transposase activity
YPDSF_1144	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_1145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPDSF_1146	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPDSF_1149	COG0402	S-adenosylhomocysteine deaminase activity
YPDSF_1155	COG3328	transposase activity
YPDSF_1162	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPDSF_1163	COG3850	Histidine kinase
YPDSF_1164	COG0387	Pfam Sodium calcium exchanger
YPDSF_1165	COG1702	phosphate starvation-inducible protein PhoH
YPDSF_1168	COG3658	cytochrome
YPDSF_1169	COG1215	transferase activity, transferring glycosyl groups
YPDSF_1170	COG1649	PFAM Uncharacterised BCR, COG1649
YPDSF_1170	COG0726	polysaccharide deacetylase
YPDSF_1171	COG0457	Tetratricopeptide repeat
YPDSF_1172	COG0006	proline dipeptidase activity
YPDSF_1176	COG0577	efflux transmembrane transporter activity
YPDSF_1176	COG1136	(ABC) transporter
YPDSF_1178	COG1136	(ABC) transporter
YPDSF_1178	COG0577	efflux transmembrane transporter activity
YPDSF_1184	COG2066	Belongs to the glutaminase family
YPDSF_1186	COG1349	DNA-binding transcription factor activity
YPDSF_1188	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPDSF_1189	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPDSF_1197	COG2030	dehydratase
YPDSF_1198	COG0427	acetyl-CoA hydrolase
YPDSF_1200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_1200	COG2205	protein histidine kinase activity
YPDSF_1203	COG3188	usher protein
YPDSF_1205	COG3121	Chaperone
YPDSF_1206	COG3328	transposase activity
YPDSF_1208	COG0582	viral genome integration into host DNA
YPDSF_1209	COG1169	isochorismate synthase
YPDSF_1210	COG2814	Major facilitator Superfamily
YPDSF_1211	COG1132	(ABC) transporter
YPDSF_1214	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPDSF_1214	COG2226	methyltransferase
YPDSF_1214	COG3433	isochorismatase activity
YPDSF_1218	COG1021	2,3-dihydroxybenzoate-AMP ligase
YPDSF_1219	COG4771	TonB-dependent receptor
YPDSF_1232	COG0395	ABC-type sugar transport system, permease component
YPDSF_1233	COG1175	transmembrane transport
YPDSF_1235	COG0673	inositol 2-dehydrogenase activity
YPDSF_1242	COG3328	transposase activity
YPDSF_1243	COG3328	transposase activity
YPDSF_1261	COG2197	response regulator
YPDSF_1263	COG3136	membrane protein required for alginate biosynthesis
YPDSF_1266	COG1113	amino acid transport
YPDSF_1269	COG2837	iron assimilation
YPDSF_1274	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPDSF_1274	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPDSF_1274	COG0506	proline dehydrogenase activity
YPDSF_1281	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YPDSF_1283	COG1191	sigma factor activity
YPDSF_1289	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPDSF_1290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPDSF_1293	COG1677	Flagellar hook-basal body complex protein FliE
YPDSF_1295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPDSF_1297	COG1157	protein secretion by the type III secretion system
YPDSF_1298	COG2882	bacterial-type flagellum organization
YPDSF_1300	COG1580	Controls the rotational direction of flagella during chemotaxis
YPDSF_1305	COG1987	bacterial-type flagellum assembly
YPDSF_1308	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_1309	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_1310	COG1129	ABC transporter
YPDSF_1312	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_1313	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1313	COG3347	Dehydrogenase
YPDSF_1314	COG2390	Transcriptional regulator
YPDSF_1316	COG1256	bacterial-type flagellum assembly
YPDSF_1320	COG4786	Flagellar basal body rod
YPDSF_1322	COG1749	Flagellar hook protein flgE
YPDSF_1323	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPDSF_1324	COG1558	bacterial-type flagellum-dependent cell motility
YPDSF_1325	COG1815	bacterial-type flagellum-dependent cell motility
YPDSF_1327	COG2747	anti-sigma28 factor FlgM
YPDSF_1328	COG3418	PFAM FlgN family protein
YPDSF_1333	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPDSF_1334	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPDSF_1339	COG2372	response to copper ion
YPDSF_1340	COG1528	Iron-storage protein
YPDSF_1343	COG1770	oligopeptidase
YPDSF_1346	COG3141	response to X-ray
YPDSF_1347	COG0513	Belongs to the DEAD box helicase family
YPDSF_1352	COG1760	l-serine dehydratase
YPDSF_1353	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPDSF_1354	COG2368	4-hydroxyphenylacetate
YPDSF_1357	COG3971	2-oxopent-4-enoate hydratase activity
YPDSF_1359	COG3384	dioxygenase
YPDSF_1360	COG1012	belongs to the aldehyde dehydrogenase family
YPDSF_1363	COG1846	Transcriptional regulator
YPDSF_1366	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_1366	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_1367	COG3715	PTS system
YPDSF_1368	COG3716	PTS system mannose fructose sorbose family IID component
YPDSF_1373	COG3447	MASE1 domain protein
YPDSF_1373	COG5002	protein histidine kinase activity
YPDSF_1373	COG5001	Diguanylate cyclase
YPDSF_1375	COG2226	methyltransferase
YPDSF_1377	COG1278	Cold shock
YPDSF_1379	COG1113	amino acid transport
YPDSF_1385	COG2207	Transcriptional regulator
YPDSF_1387	COG1132	(ABC) transporter
YPDSF_1388	COG1943	Transposase
YPDSF_1393	COG2223	nitrite transmembrane transporter activity
YPDSF_1397	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPDSF_1401	COG3122	Protein conserved in bacteria
YPDSF_1405	COG0534	Mate efflux family protein
YPDSF_1408	COG4948	Mandelate Racemase Muconate Lactonizing
YPDSF_1410	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1411	COG3011	Protein conserved in bacteria
YPDSF_1412	COG2271	Major facilitator Superfamily
YPDSF_1414	COG1470	cell adhesion involved in biofilm formation
YPDSF_1414	COG1388	LysM domain
YPDSF_1415	COG3328	transposase activity
YPDSF_1418	COG2925	Exonuclease
YPDSF_1419	COG0531	amino acid
YPDSF_1420	COG0371	Dehydrogenase
YPDSF_1423	COG1129	ABC transporter
YPDSF_1424	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_1426	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_1428	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPDSF_1430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPDSF_1430	COG0131	Imidazoleglycerol-phosphate dehydratase
YPDSF_1431	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YPDSF_1434	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPDSF_1434	COG0140	phosphoribosyl-ATP diphosphatase activity
YPDSF_1436	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPDSF_1437	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPDSF_1440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPDSF_1441	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_1442	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_1443	COG1120	ATPase activity
YPDSF_1446	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPDSF_1447	COG0076	glutamate decarboxylase activity
YPDSF_1448	COG4114	ferric iron reductase
YPDSF_1449	COG1253	flavin adenine dinucleotide binding
YPDSF_1450	COG2982	Protein involved in outer membrane biogenesis
YPDSF_1453	COG0489	protein tyrosine kinase activity
YPDSF_1455	COG1943	Transposase
YPDSF_1459	COG2814	Major facilitator Superfamily
YPDSF_1461	COG1346	cytolysis
YPDSF_1464	COG2949	membrane
YPDSF_1468	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPDSF_1471	COG2311	Membrane
YPDSF_1473	COG0477	Major facilitator Superfamily
YPDSF_1474	COG0583	DNA-binding transcription factor activity
YPDSF_1479	COG1136	(ABC) transporter
YPDSF_1481	COG0303	'Molybdopterin
YPDSF_1484	COG0488	(ABC) transporter
YPDSF_1512	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPDSF_1514	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1515	COG1024	Enoyl-CoA hydratase
YPDSF_1517	COG3425	synthase
YPDSF_1518	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1519	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_1520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPDSF_1522	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1527	COG2920	part of a sulfur-relay system
YPDSF_1531	COG1832	CoA-binding protein
YPDSF_1532	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YPDSF_1534	COG0210	DNA helicase
YPDSF_1535	COG3304	Inner membrane component domain
YPDSF_1536	COG1289	transmembrane transporter activity
YPDSF_1537	COG3070	regulator of competence-specific genes
YPDSF_1539	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPDSF_1539	COG2885	chlorophyll binding
YPDSF_1540	COG1943	Transposase
YPDSF_1542	COG1067	ATP-dependent peptidase activity
YPDSF_1544	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_1547	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_1548	COG1943	Transposase
YPDSF_1550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPDSF_1554	COG0681	Belongs to the peptidase S26 family
YPDSF_1557	COG3086	response to oxidative stress
YPDSF_1558	COG3026	antisigma factor binding
YPDSF_1559	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YPDSF_1561	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPDSF_1563	COG0513	Belongs to the DEAD box helicase family
YPDSF_1572	COG1984	allophanate hydrolase subunit 2
YPDSF_1573	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YPDSF_1574	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPDSF_1575	COG5212	phosphodiesterase
YPDSF_1577	COG3272	Protein of unknown function (DUF1722)
YPDSF_1585	COG0745	RESPONSE REGULATOR receiver
YPDSF_1589	COG0033	Phosphoglucomutase
YPDSF_1590	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPDSF_1593	COG2169	Transcriptional regulator
YPDSF_1593	COG1917	Cupin 2, conserved barrel domain protein
YPDSF_1594	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPDSF_1595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPDSF_1596	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPDSF_1598	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPDSF_1599	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPDSF_1600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPDSF_1602	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPDSF_1603	COG4413	Urea transporter
YPDSF_1606	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPDSF_1612	COG1124	(ABC) transporter
YPDSF_1613	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPDSF_1614	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPDSF_1616	COG0747	negative chemotaxis
YPDSF_1617	COG1278	Cold shock
YPDSF_1624	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPDSF_1625	COG4175	Glycine betaine
YPDSF_1626	COG4176	ABC-type proline glycine betaine transport system permease component
YPDSF_1627	COG2113	Glycine betaine
YPDSF_1629	COG1953	Uracil, thiamine, allantoin
YPDSF_1630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPDSF_1632	COG2226	methyltransferase
YPDSF_1634	COG1388	LysM domain
YPDSF_1634	COG0741	lytic transglycosylase activity
YPDSF_1636	COG0656	L-ascorbic acid biosynthetic process
YPDSF_1637	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPDSF_1639	COG2011	ABC-type metal ion transport system permease component
YPDSF_1640	COG1464	Belongs to the NlpA lipoprotein family
YPDSF_1642	COG1720	tRNA m6t6A37 methyltransferase activity
YPDSF_1644	COG3015	lipoprotein NlpE involved in copper resistance
YPDSF_1646	COG4681	YaeQ
YPDSF_1648	COG4568	rho-dependent transcription termination
YPDSF_1650	COG0037	tRNA processing
YPDSF_1651	COG0346	lactoylglutathione lyase activity
YPDSF_1653	COG0587	DNA-directed DNA polymerase activity
YPDSF_1655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPDSF_1659	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YPDSF_1661	COG0750	zinc metalloprotease
YPDSF_1662	COG0575	Belongs to the CDS family
YPDSF_1663	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YPDSF_1670	COG0024	Methionine aminopeptidase
YPDSF_1675	COG0564	pseudouridine synthase activity
YPDSF_1676	COG3098	single-species biofilm formation
YPDSF_1677	COG1943	Transposase
YPDSF_1680	COG1611	Belongs to the LOG family
YPDSF_1681	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPDSF_1683	COG2363	Small membrane protein
YPDSF_1684	COG0583	DNA-binding transcription factor activity
YPDSF_1685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPDSF_1686	COG2166	iron-sulfur cluster assembly
YPDSF_1687	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPDSF_1688	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPDSF_1689	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPDSF_1690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YPDSF_1690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YPDSF_1694	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPDSF_1695	COG1074	ATP-dependent DNA helicase activity
YPDSF_1697	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPDSF_1707	COG0667	Aldo Keto reductase
YPDSF_1712	COG1609	Transcriptional regulator
YPDSF_1713	COG0019	diaminopimelate decarboxylase activity
YPDSF_1714	COG0583	DNA-binding transcription factor activity
YPDSF_1715	COG2814	Major facilitator Superfamily
YPDSF_1716	COG0583	DNA-binding transcription factor activity
YPDSF_1719	COG0840	transmembrane signaling receptor activity
YPDSF_1721	COG3328	transposase activity
YPDSF_1722	COG1917	Cupin 2, conserved barrel domain protein
YPDSF_1724	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1726	COG1175	transmembrane transport
YPDSF_1727	COG0395	ABC-type sugar transport system, permease component
YPDSF_1728	COG3842	ATPase activity
YPDSF_1729	COG1653	transport
YPDSF_1730	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPDSF_1731	COG1988	membrane-bound metal-dependent
YPDSF_1733	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPDSF_1735	COG0823	Involved in the tonB-independent uptake of proteins
YPDSF_1736	COG2814	Major facilitator Superfamily
YPDSF_1737	COG3121	Chaperone
YPDSF_1740	COG3121	Chaperone
YPDSF_1741	COG3539	Fimbrial protein
YPDSF_1743	COG0793	Belongs to the peptidase S41A family
YPDSF_1745	COG1956	GAF domain-containing protein
YPDSF_1746	COG2995	paraquat-inducible protein a
YPDSF_1747	COG3008	intermembrane lipid transfer
YPDSF_1751	COG3121	Chaperone
YPDSF_1761	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPDSF_1763	COG5295	Hep Hag repeat protein
YPDSF_1765	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPDSF_1767	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPDSF_1768	COG0745	RESPONSE REGULATOR receiver
YPDSF_1770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPDSF_1771	COG0840	transmembrane signaling receptor activity
YPDSF_1772	COG0840	transmembrane signaling receptor activity
YPDSF_1776	COG2964	Protein conserved in bacteria
YPDSF_1778	COG0251	oxidation-reduction process
YPDSF_1779	COG2271	Major facilitator Superfamily
YPDSF_1780	COG0835	chemotaxis
YPDSF_1781	COG2198	Histidine kinase
YPDSF_1781	COG0643	Histidine kinase
YPDSF_1782	COG1360	Flagellar Motor Protein
YPDSF_1787	COG1285	pathogenesis
YPDSF_1788	COG0840	transmembrane signaling receptor activity
YPDSF_1789	COG0840	transmembrane signaling receptor activity
YPDSF_1791	COG1278	Cold shock
YPDSF_1793	COG3321	synthase
YPDSF_1793	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1793	COG0604	alcohol dehydrogenase
YPDSF_1796	COG1522	sequence-specific DNA binding
YPDSF_1802	COG1733	regulation of RNA biosynthetic process
YPDSF_1803	COG0702	epimerase
YPDSF_1804	COG0840	transmembrane signaling receptor activity
YPDSF_1807	COG0538	isocitrate dehydrogenase activity
YPDSF_1808	COG1187	pseudouridine synthase activity
YPDSF_1812	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPDSF_1814	COG0745	RESPONSE REGULATOR receiver
YPDSF_1816	COG2850	peptidyl-arginine hydroxylation
YPDSF_1818	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YPDSF_1821	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPDSF_1823	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPDSF_1824	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPDSF_1825	COG3134	Outer membrane lipoprotein
YPDSF_1826	COG3328	transposase activity
YPDSF_1830	COG1252	NADH dehydrogenase
YPDSF_1832	COG1472	Belongs to the glycosyl hydrolase 3 family
YPDSF_1835	COG5633	Lipoprotein
YPDSF_1836	COG0537	adenosine 5'-monophosphoramidase activity
YPDSF_1837	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPDSF_1839	COG1263	PTS System
YPDSF_1839	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_1840	COG0084	hydrolase, TatD family'
YPDSF_1841	COG0470	DNA polymerase III
YPDSF_1843	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPDSF_1844	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPDSF_1845	COG1943	Transposase
YPDSF_1846	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_1848	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1852	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPDSF_1853	COG1399	metal-binding, possibly nucleic acid-binding protein
YPDSF_1855	COG0564	pseudouridine synthase activity
YPDSF_1856	COG1530	ribonuclease E activity
YPDSF_1858	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPDSF_1862	COG3328	transposase activity
YPDSF_1865	COG0628	permease
YPDSF_1871	COG3916	Acyl-homoserine-lactone synthase
YPDSF_1872	COG2771	luxR family
YPDSF_1873	COG0583	DNA-binding transcription factor activity
YPDSF_1874	COG0477	Major facilitator Superfamily
YPDSF_1876	COG0667	Aldo Keto reductase
YPDSF_1881	COG1203	CRISPR-associated helicase, Cas3
YPDSF_1882	COG1518	maintenance of DNA repeat elements
YPDSF_1883	COG0668	transmembrane transport
YPDSF_1887	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPDSF_1888	COG0395	ABC-type sugar transport system, permease component
YPDSF_1891	COG1609	Transcriptional regulator
YPDSF_1893	COG3842	ATPase activity
YPDSF_1896	COG3210	domain, Protein
YPDSF_1899	COG3210	domain, Protein
YPDSF_1902	COG3210	domain, Protein
YPDSF_1903	COG2831	hemolysin activation secretion protein
YPDSF_1904	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_1905	COG4638	Rieske (2fe-2S)
YPDSF_1906	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPDSF_1907	COG0473	3-isopropylmalate dehydrogenase activity
YPDSF_1908	COG0583	DNA-binding transcription factor activity
YPDSF_1909	COG1609	Transcriptional regulator
YPDSF_1910	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_1913	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_1914	COG1063	alcohol dehydrogenase
YPDSF_1918	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPDSF_1924	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_1925	COG0765	amino acid transport
YPDSF_1926	COG1126	abc transporter atp-binding protein
YPDSF_1932	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPDSF_1935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPDSF_1938	COG1169	isochorismate synthase
YPDSF_1940	COG4575	ribosome binding
YPDSF_1943	COG0129	dihydroxy-acid dehydratase activity
YPDSF_1946	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPDSF_1947	COG1609	Transcriptional regulator
YPDSF_1949	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_1950	COG3265	gluconokinase activity
YPDSF_1951	COG2731	YhcH YjgK YiaL family protein
YPDSF_1954	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPDSF_1955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPDSF_1957	COG0839	Belongs to the complex I subunit 6 family
YPDSF_1960	COG1034	ATP synthesis coupled electron transport
YPDSF_1962	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
YPDSF_1964	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPDSF_1966	COG0583	DNA-binding transcription factor activity
YPDSF_1967	COG0436	Aminotransferase
YPDSF_1969	COG0490	domain, Protein
YPDSF_1969	COG0471	metal ion transport
YPDSF_1970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_1974	COG0280	phosphate acetyltransferase
YPDSF_1974	COG0857	belongs to the CobB CobQ family
YPDSF_1975	COG1609	Transcriptional regulator
YPDSF_1978	COG3037	sugar-specific permease SgaT UlaA
YPDSF_1979	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPDSF_1983	COG1090	epimerase
YPDSF_1984	COG4598	ABC transporter
YPDSF_1985	COG4160	amino acid transport
YPDSF_1986	COG4215	(ABC) transporter
YPDSF_1987	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_1988	COG0163	prenyltransferase activity
YPDSF_1989	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPDSF_1990	COG1286	toxin biosynthetic process
YPDSF_1991	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPDSF_1992	COG0285	dihydrofolate synthase activity
YPDSF_1994	COG0586	Pfam SNARE associated Golgi protein
YPDSF_1996	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPDSF_1999	COG0697	spore germination
YPDSF_2002	COG1794	racemase activity, acting on amino acids and derivatives
YPDSF_2003	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_2006	COG3101	peptidyl-lysine hydroxylation
YPDSF_2007	COG0730	response to heat
YPDSF_2010	COG2890	protein-(glutamine-N5) methyltransferase activity
YPDSF_2012	COG2062	phosphohistidine phosphatase, SixA
YPDSF_2015	COG3691	Protein conserved in bacteria
YPDSF_2018	COG3088	subunit of a heme lyase
YPDSF_2018	COG4235	cytochrome complex assembly
YPDSF_2019	COG4235	cytochrome complex assembly
YPDSF_2019	COG3088	subunit of a heme lyase
YPDSF_2020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPDSF_2021	COG1138	Cytochrome C-type biogenesis protein
YPDSF_2023	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPDSF_2024	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPDSF_2025	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPDSF_2028	COG1704	LemA family
YPDSF_2030	COG2824	Alkylphosphonate utilization operon protein PhnA
YPDSF_2036	COG3501	Rhs element vgr protein
YPDSF_2049	COG3188	usher protein
YPDSF_2050	COG3328	transposase activity
YPDSF_2051	COG3188	usher protein
YPDSF_2052	COG3121	Chaperone
YPDSF_2065	COG2951	lytic endotransglycosylase activity
YPDSF_2072	COG0243	molybdopterin cofactor binding
YPDSF_2073	COG0437	4 iron, 4 sulfur cluster binding
YPDSF_2074	COG3302	dmso reductase anchor subunit
YPDSF_2075	COG3381	protein complex oligomerization
YPDSF_2081	COG3038	cytochrome b561
YPDSF_2082	COG0436	Aminotransferase
YPDSF_2087	COG0667	Aldo Keto reductase
YPDSF_2090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPDSF_2091	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPDSF_2093	COG1943	Transposase
YPDSF_2096	COG3530	Putative quorum-sensing-regulated virulence factor
YPDSF_2099	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPDSF_2100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPDSF_2101	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_2103	COG2190	(PTS) system
YPDSF_2105	COG2205	protein histidine kinase activity
YPDSF_2106	COG0745	RESPONSE REGULATOR receiver
YPDSF_2107	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_2110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPDSF_2111	COG0006	proline dipeptidase activity
YPDSF_2113	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPDSF_2115	COG5002	protein histidine kinase activity
YPDSF_2115	COG3850	Histidine kinase
YPDSF_2116	COG0745	RESPONSE REGULATOR receiver
YPDSF_2119	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YPDSF_2120	COG4208	sulfate ABC transporter
YPDSF_2121	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPDSF_2122	COG4150	thiosulfate binding
YPDSF_2124	COG1737	Transcriptional regulator
YPDSF_2125	COG2731	YhcH YjgK YiaL family protein
YPDSF_2127	COG4886	Leucine-rich repeat (LRR) protein
YPDSF_2129	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPDSF_2130	COG2837	iron assimilation
YPDSF_2133	COG3111	PFAM Bacterial OB fold (BOF) protein
YPDSF_2141	COG3005	denitrification pathway
YPDSF_2142	COG3043	anaerobic respiration
YPDSF_2144	COG3062	negative regulation of establishment of protein localization
YPDSF_2145	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_2145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_2146	COG2197	response regulator
YPDSF_2148	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_2150	COG1988	membrane-bound metal-dependent
YPDSF_2151	COG0641	radical SAM
YPDSF_2152	COG3119	arylsulfatase activity
YPDSF_2153	COG3842	ATPase activity
YPDSF_2154	COG1175	transmembrane transport
YPDSF_2155	COG1840	ABC-type Fe3 transport system, periplasmic component
YPDSF_2157	COG1393	Belongs to the ArsC family
YPDSF_2159	COG1876	peptidase activity
YPDSF_2163	COG2321	neutral zinc metallopeptidase
YPDSF_2165	COG1943	Transposase
YPDSF_2166	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPDSF_2168	COG2716	regulation of RNA biosynthetic process
YPDSF_2169	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPDSF_2172	COG0628	permease
YPDSF_2173	COG4783	chaperone-mediated protein folding
YPDSF_2174	COG1393	Belongs to the ArsC family
YPDSF_2176	COG1943	Transposase
YPDSF_2179	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPDSF_2180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPDSF_2184	COG0581	inorganic phosphate transmembrane transporter activity
YPDSF_2186	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPDSF_2187	COG0248	Ppx GppA phosphatase
YPDSF_2189	COG2239	Acts as a magnesium transporter
YPDSF_2190	COG0443	Heat shock 70 kDa protein
YPDSF_2191	COG1177	transmembrane transport
YPDSF_2192	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPDSF_2194	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPDSF_2196	COG3842	ATPase activity
YPDSF_2202	COG2205	protein histidine kinase activity
YPDSF_2203	COG0745	RESPONSE REGULATOR receiver
YPDSF_2204	COG3422	double-strand break repair
YPDSF_2209	COG0351	phosphomethylpyrimidine kinase
YPDSF_2212	COG3328	transposase activity
YPDSF_2214	COG1943	Transposase
YPDSF_2216	COG0516	GMP reductase activity
YPDSF_2216	COG0517	IMP dehydrogenase activity
YPDSF_2218	COG1645	bacterial-type flagellum-dependent swarming motility
YPDSF_2221	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPDSF_2222	COG2976	Protein conserved in bacteria
YPDSF_2230	COG3468	outer membrane autotransporter barrel domain protein
YPDSF_2231	COG3468	outer membrane autotransporter barrel domain protein
YPDSF_2235	COG2975	iron-sulfur cluster assembly
YPDSF_2236	COG0633	Ferredoxin
YPDSF_2237	COG0443	Heat shock 70 kDa protein
YPDSF_2240	COG0822	iron-sulfur transferase activity
YPDSF_2241	COG1104	cysteine desulfurase activity
YPDSF_2244	COG0483	inositol monophosphate 1-phosphatase activity
YPDSF_2245	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPDSF_2246	COG3683	transport system, periplasmic component
YPDSF_2247	COG3711	transcriptional antiterminator
YPDSF_2248	COG2814	Major facilitator Superfamily
YPDSF_2252	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_2252	COG1017	nitric oxide dioxygenase activity
YPDSF_2255	COG2188	Transcriptional regulator
YPDSF_2256	COG0347	Belongs to the P(II) protein family
YPDSF_2257	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPDSF_2257	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPDSF_2258	COG2204	response regulator
YPDSF_2259	COG3170	Tfp pilus assembly protein FimV
YPDSF_2260	COG2205	protein histidine kinase activity
YPDSF_2266	COG0590	tRNA wobble adenosine to inosine editing
YPDSF_2267	COG0560	Phosphoserine phosphatase
YPDSF_2269	COG1737	Transcriptional regulator
YPDSF_2270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_2271	COG1943	Transposase
YPDSF_2272	COG3130	regulation of translation
YPDSF_2273	COG3009	Protein conserved in bacteria
YPDSF_2274	COG3008	intermembrane lipid transfer
YPDSF_2274	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPDSF_2275	COG2995	paraquat-inducible protein a
YPDSF_2276	COG0488	(ABC) transporter
YPDSF_2278	COG0633	Ferredoxin
YPDSF_2278	COG3217	Mosc domain protein beta barrel domain protein
YPDSF_2281	COG0308	aminopeptidase N
YPDSF_2285	COG1448	Aminotransferase
YPDSF_2286	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPDSF_2287	COG3108	Peptidase M15
YPDSF_2288	COG2989	Protein conserved in bacteria
YPDSF_2291	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YPDSF_2292	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YPDSF_2293	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPDSF_2294	COG3173	Aminoglycoside phosphotransferase
YPDSF_2296	COG2835	tetraacyldisaccharide 4'-kinase activity
YPDSF_2297	COG1278	Cold shock
YPDSF_2298	COG5383	Protein conserved in bacteria
YPDSF_2301	COG2333	competence protein COMEC
YPDSF_2301	COG0658	competence protein
YPDSF_2303	COG0539	negative regulation of cytoplasmic translation
YPDSF_2308	COG5295	Hep Hag repeat protein
YPDSF_2308	COG5295	Hep Hag repeat protein
YPDSF_2309	COG0252	asparaginase activity
YPDSF_2310	COG1944	ATP diphosphatase activity
YPDSF_2311	COG2116	formate transmembrane transporter activity
YPDSF_2312	COG1882	Formate acetyltransferase
YPDSF_2314	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPDSF_2315	COG2814	Major facilitator Superfamily
YPDSF_2317	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPDSF_2319	COG1674	ftsk spoiiie
YPDSF_2319	COG3107	peptidoglycan biosynthetic process
YPDSF_2321	COG0492	ferredoxin-NADP+ reductase activity
YPDSF_2323	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPDSF_2325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPDSF_2327	COG0542	response to heat
YPDSF_2330	COG1278	Cold shock
YPDSF_2332	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_2334	COG2990	Protein conserved in bacteria
YPDSF_2335	COG3593	DNA synthesis involved in DNA repair
YPDSF_2336	COG2431	L-lysine efflux transmembrane transporter activity
YPDSF_2338	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_2339	COG0028	Belongs to the TPP enzyme family
YPDSF_2340	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPDSF_2341	COG0702	epimerase
YPDSF_2342	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_2345	COG1605	Chorismate mutase
YPDSF_2346	COG1126	abc transporter atp-binding protein
YPDSF_2347	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_2348	COG4215	(ABC) transporter
YPDSF_2349	COG4160	amino acid transport
YPDSF_2354	COG1120	ATPase activity
YPDSF_2355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_2359	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_2362	COG1177	transmembrane transport
YPDSF_2363	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPDSF_2364	COG3842	ATPase activity
YPDSF_2366	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPDSF_2369	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPDSF_2370	COG2985	domain, Protein
YPDSF_2370	COG0569	domain protein
YPDSF_2372	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_2373	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPDSF_2374	COG1349	DNA-binding transcription factor activity
YPDSF_2375	COG0814	amino acid
YPDSF_2376	COG1686	Belongs to the peptidase S11 family
YPDSF_2377	COG2011	ABC-type metal ion transport system permease component
YPDSF_2382	COG0625	glutathione transferase activity
YPDSF_2383	COG4771	TonB-dependent receptor
YPDSF_2385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_2388	COG0833	amino acid
YPDSF_2389	COG0583	DNA-binding transcription factor activity
YPDSF_2390	COG2855	membrane
YPDSF_2392	COG3188	usher protein
YPDSF_2393	COG3121	Chaperone
YPDSF_2396	COG3710	Transcriptional regulator
YPDSF_2397	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPDSF_2397	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_2397	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_2398	COG1105	Belongs to the carbohydrate kinase PfkB family
YPDSF_2400	COG0494	nUDIX hydrolase
YPDSF_2401	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_2402	COG1129	ABC transporter
YPDSF_2404	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPDSF_2409	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_2413	COG1312	Catalyzes the dehydration of D-mannonate
YPDSF_2414	COG0246	Mannitol dehydrogenase
YPDSF_2415	COG2186	Transcriptional regulator
YPDSF_2417	COG0523	cobalamin synthesis protein
YPDSF_2418	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_2419	COG0791	NLP P60 protein
YPDSF_2420	COG2200	EAL domain
YPDSF_2421	COG4166	transmembrane transport
YPDSF_2422	COG4174	ABC transporter (Permease)
YPDSF_2423	COG4239	(ABC) transporter, permease
YPDSF_2424	COG4172	Belongs to the ABC transporter superfamily
YPDSF_2427	COG2814	Major facilitator Superfamily
YPDSF_2428	COG1187	pseudouridine synthase activity
YPDSF_2429	COG1061	Type III restriction enzyme res subunit
YPDSF_2431	COG1943	Transposase
YPDSF_2433	COG3082	Protein of unknown function (DUF1414)
YPDSF_2434	COG3083	sulfuric ester hydrolase activity
YPDSF_2436	COG3157	Type VI secretion system effector, Hcp
YPDSF_2439	COG2723	6-phospho-beta-galactosidase activity
YPDSF_2440	COG1737	Transcriptional regulator
YPDSF_2444	COG3299	homolog of phage Mu protein gp47
YPDSF_2453	COG4386	tail sheath protein
YPDSF_2457	COG3622	Belongs to the hyi family
YPDSF_2458	COG1349	DNA-binding transcription factor activity
YPDSF_2459	COG0235	Class ii aldolase
YPDSF_2460	COG3395	kinase activity
YPDSF_2469	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPDSF_2470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPDSF_2473	COG0642	Histidine kinase
YPDSF_2473	COG2198	Histidine kinase
YPDSF_2474	COG2198	Histidine kinase
YPDSF_2474	COG0642	Histidine kinase
YPDSF_2476	COG2205	protein histidine kinase activity
YPDSF_2476	COG0784	Response regulator, receiver
YPDSF_2481	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_2484	COG0814	amino acid
YPDSF_2490	COG0697	spore germination
YPDSF_2492	COG1982	Orn Lys Arg decarboxylase major
YPDSF_2493	COG3328	transposase activity
YPDSF_2494	COG1982	Orn Lys Arg decarboxylase major
YPDSF_2495	COG0531	amino acid
YPDSF_2497	COG1174	glycine betaine transport
YPDSF_2498	COG1125	glycine betaine transport
YPDSF_2499	COG1174	glycine betaine transport
YPDSF_2500	COG1732	Glycine betaine
YPDSF_2501	COG2897	thiosulfate sulfurtransferase activity
YPDSF_2504	COG0410	ABC transporter
YPDSF_2505	COG1122	ATPase activity
YPDSF_2509	COG4807	Protein conserved in bacteria
YPDSF_2512	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPDSF_2514	COG2261	transglycosylase associated protein
YPDSF_2517	COG1403	HNH endonuclease
YPDSF_2519	COG0277	FAD linked oxidase domain protein
YPDSF_2520	COG1686	Belongs to the peptidase S11 family
YPDSF_2522	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPDSF_2525	COG2211	Major facilitator Superfamily
YPDSF_2526	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPDSF_2528	COG0583	DNA-binding transcription factor activity
YPDSF_2529	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPDSF_2533	COG1943	Transposase
YPDSF_2534	COG0670	Belongs to the BI1 family
YPDSF_2535	COG0314	molybdopterin synthase activity
YPDSF_2536	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPDSF_2538	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPDSF_2539	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPDSF_2540	COG4628	conserved protein (DUF2132)
YPDSF_2541	COG0556	nucleotide-excision repair
YPDSF_2543	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPDSF_2544	COG2226	methyltransferase
YPDSF_2549	COG0561	phosphatase activity
YPDSF_2551	COG4149	molybdate abc transporter
YPDSF_2552	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPDSF_2554	COG2005	Transcriptional regulator
YPDSF_2554	COG3585	molybdate ion transport
YPDSF_2555	COG1119	ATPase activity
YPDSF_2558	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPDSF_2559	COG1085	galactose-1-phosphate uridylyltransferase
YPDSF_2562	COG2017	converts alpha-aldose to the beta-anomer
YPDSF_2567	COG1230	cation diffusion facilitator family transporter
YPDSF_2570	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPDSF_2571	COG2885	chlorophyll binding
YPDSF_2573	COG3064	Membrane
YPDSF_2573	COG3064	Membrane
YPDSF_2574	COG0848	biopolymer transport protein
YPDSF_2575	COG0811	peptide transport
YPDSF_2576	COG0824	Thioesterase
YPDSF_2577	COG3790	cyd operon protein YbgE
YPDSF_2578	COG1294	oxidase, subunit
YPDSF_2579	COG1271	oxidase subunit
YPDSF_2580	COG1943	Transposase
YPDSF_2581	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPDSF_2583	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPDSF_2584	COG0567	Dehydrogenase, E1 component
YPDSF_2586	COG1053	succinate dehydrogenase
YPDSF_2587	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPDSF_2588	COG2009	succinate dehydrogenase
YPDSF_2591	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPDSF_2592	COG0497	DNA recombination
YPDSF_2593	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPDSF_2595	COG2867	negative regulation of translational initiation
YPDSF_2598	COG0582	viral genome integration into host DNA
YPDSF_2609	COG3657	addiction module killer protein
YPDSF_2614	COG2963	transposase activity
YPDSF_2616	COG0596	Alpha beta hydrolase
YPDSF_2620	COG0735	belongs to the Fur family
YPDSF_2625	COG2190	(PTS) system
YPDSF_2625	COG1263	PTS System
YPDSF_2625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_2627	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPDSF_2628	COG1940	carbohydrate kinase activity
YPDSF_2628	COG1846	Transcriptional regulator
YPDSF_2629	COG0647	UMP catabolic process
YPDSF_2630	COG0367	asparagine synthase
YPDSF_2631	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPDSF_2633	COG1702	phosphate starvation-inducible protein PhoH
YPDSF_2636	COG4535	Mg2 and Co2 transporter CorC
YPDSF_2637	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPDSF_2639	COG0765	amino acid transport
YPDSF_2640	COG0765	amino acid transport
YPDSF_2641	COG1126	abc transporter atp-binding protein
YPDSF_2642	COG2888	peptidyl-tyrosine sulfation
YPDSF_2645	COG1466	dna polymerase III delta subunit
YPDSF_2647	COG0799	negative regulation of ribosome biogenesis
YPDSF_2649	COG0768	penicillin binding
YPDSF_2650	COG0772	Belongs to the SEDS family
YPDSF_2651	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPDSF_2652	COG1686	Belongs to the peptidase S11 family
YPDSF_2656	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPDSF_2658	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPDSF_2659	COG1278	Cold shock
YPDSF_2660	COG1278	Cold shock
YPDSF_2661	COG2197	response regulator
YPDSF_2666	COG5265	(ABC) transporter
YPDSF_2667	COG3718	enzyme involved in inositol metabolism
YPDSF_2669	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_2670	COG0673	inositol 2-dehydrogenase activity
YPDSF_2671	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_2672	COG1129	ABC transporter
YPDSF_2673	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_2674	COG0673	inositol 2-dehydrogenase activity
YPDSF_2675	COG0673	inositol 2-dehydrogenase activity
YPDSF_2676	COG3962	Belongs to the TPP enzyme family
YPDSF_2679	COG2373	Large extracellular alpha-helical protein
YPDSF_2680	COG4953	penicillin-binding protein 1C
YPDSF_2681	COG3423	Transcriptional regulator
YPDSF_2689	COG3328	transposase activity
YPDSF_2695	COG0656	L-ascorbic acid biosynthetic process
YPDSF_2696	COG0667	Aldo Keto reductase
YPDSF_2701	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_2701	COG2453	phosphatase
YPDSF_2702	COG2267	carboxylic ester hydrolase activity
YPDSF_2704	COG4589	Belongs to the CDS family
YPDSF_2705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPDSF_2709	COG2501	S4 domain
YPDSF_2710	COG1943	Transposase
YPDSF_2712	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPDSF_2714	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPDSF_2715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPDSF_2716	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPDSF_2717	COG4181	ATPase activity
YPDSF_2718	COG2755	lipolytic protein G-D-S-L family
YPDSF_2719	COG0300	oxidoreductase activity
YPDSF_2720	COG3118	belongs to the thioredoxin family
YPDSF_2721	COG0330	HflC and HflK could
YPDSF_2722	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPDSF_2723	COG0789	Transcriptional regulator
YPDSF_2724	COG2217	Heavy metal translocating P-type atpase
YPDSF_2725	COG3735	TraB family
YPDSF_2726	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPDSF_2728	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_2729	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_2730	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_2733	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPDSF_2733	COG4651	solute:proton antiporter activity
YPDSF_2734	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_2735	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPDSF_2739	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_2740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YPDSF_2741	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YPDSF_2748	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_2752	COG0543	2 iron, 2 sulfur cluster binding
YPDSF_2752	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_2759	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPDSF_2761	COG2832	Protein of unknown function (DUF454)
YPDSF_2764	COG3264	Mechanosensitive ion channel
YPDSF_2764	COG1196	nuclear chromosome segregation
YPDSF_2765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPDSF_2766	COG1309	transcriptional regulator
YPDSF_2767	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_2768	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_2770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPDSF_2774	COG3695	enzyme binding
YPDSF_2775	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPDSF_2776	COG1946	Acyl-CoA thioesterase
YPDSF_2777	COG0004	ammonium transporteR
YPDSF_2778	COG0347	Belongs to the P(II) protein family
YPDSF_2779	COG1132	(ABC) transporter
YPDSF_2780	COG1132	(ABC) transporter
YPDSF_2781	COG1522	sequence-specific DNA binding
YPDSF_2784	COG4533	DNA binding
YPDSF_2786	COG0824	Thioesterase
YPDSF_2787	COG1555	photosystem II stabilization
YPDSF_2788	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPDSF_2789	COG1943	Transposase
YPDSF_2790	COG0776	regulation of translation
YPDSF_2791	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPDSF_2795	COG0271	Belongs to the BolA IbaG family
YPDSF_2796	COG3056	Lipoprotein
YPDSF_2797	COG2223	nitrite transmembrane transporter activity
YPDSF_2799	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPDSF_2800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPDSF_2801	COG1845	cytochrome c oxidase, subunit III
YPDSF_2802	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPDSF_2804	COG2814	Major facilitator Superfamily
YPDSF_2806	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPDSF_2807	COG0693	protein deglycase activity
YPDSF_2811	COG0142	geranyltranstransferase activity
YPDSF_2814	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPDSF_2815	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPDSF_2818	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPDSF_2818	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPDSF_2823	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPDSF_2824	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPDSF_2825	COG1862	Preprotein translocase
YPDSF_2827	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YPDSF_2828	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YPDSF_2829	COG0450	alkyl hydroperoxide reductase
YPDSF_2833	COG0366	Alpha amylase catalytic
YPDSF_2835	COG1114	Component of the transport system for branched-chain amino acids
YPDSF_2837	COG5002	protein histidine kinase activity
YPDSF_2838	COG0745	RESPONSE REGULATOR receiver
YPDSF_2839	COG0420	3'-5' exonuclease activity
YPDSF_2840	COG0419	ATPase involved in DNA repair
YPDSF_2841	COG1940	carbohydrate kinase activity
YPDSF_2846	COG2226	methyltransferase
YPDSF_2856	COG0583	DNA-binding transcription factor activity
YPDSF_2857	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPDSF_2861	COG1477	protein flavinylation
YPDSF_2865	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPDSF_2866	COG1805	sodium ion transport
YPDSF_2867	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPDSF_2869	COG3034	peptidoglycan biosynthetic process
YPDSF_2870	COG0121	glutamine amidotransferase
YPDSF_2872	COG1960	acyl-CoA dehydrogenase activity
YPDSF_2875	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPDSF_2883	COG0436	Aminotransferase
YPDSF_2886	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPDSF_2889	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPDSF_2899	COG2814	Major facilitator Superfamily
YPDSF_2900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPDSF_2902	COG1846	Transcriptional regulator
YPDSF_2903	COG1566	PFAM secretion protein HlyD family protein
YPDSF_2904	COG2814	Major facilitator Superfamily
YPDSF_2905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPDSF_2906	COG3118	belongs to the thioredoxin family
YPDSF_2908	COG1042	CoA-binding domain protein
YPDSF_2908	COG0045	succinate-CoA ligase (ADP-forming) activity
YPDSF_2908	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPDSF_2909	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPDSF_2910	COG5544	Lipoprotein
YPDSF_2911	COG0542	response to heat
YPDSF_2913	COG0564	pseudouridine synthase activity
YPDSF_2914	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPDSF_2915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPDSF_2917	COG1605	Chorismate mutase
YPDSF_2917	COG0077	Prephenate dehydratase
YPDSF_2918	COG1605	Chorismate mutase
YPDSF_2918	COG0287	Prephenate dehydrogenase
YPDSF_2919	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPDSF_2925	COG0237	dephospho-CoA kinase activity
YPDSF_2927	COG1459	type II secretion system
YPDSF_2928	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPDSF_2929	COG4969	Belongs to the N-Me-Phe pilin family
YPDSF_2931	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPDSF_2932	COG3725	Membrane protein required for beta-lactamase induction
YPDSF_2933	COG1113	amino acid transport
YPDSF_2934	COG2186	Transcriptional regulator
YPDSF_2935	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPDSF_2936	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPDSF_2938	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPDSF_2939	COG1943	Transposase
YPDSF_2940	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPDSF_2942	COG0697	spore germination
YPDSF_2946	COG2132	Multicopper oxidase
YPDSF_2947	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPDSF_2948	COG0288	reversible hydration of carbon dioxide
YPDSF_2949	COG1131	(ABC) transporter
YPDSF_2950	COG0842	Transport permease protein
YPDSF_2952	COG0726	polysaccharide deacetylase
YPDSF_2956	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPDSF_2957	COG0617	tRNA 3'-terminal CCA addition
YPDSF_2958	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YPDSF_2959	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YPDSF_2961	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPDSF_2962	COG1643	Atp-dependent helicase
YPDSF_2963	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPDSF_2966	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPDSF_2967	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_2972	COG2860	membrane
YPDSF_2974	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPDSF_2976	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPDSF_2977	COG3850	Histidine kinase
YPDSF_2977	COG3437	response regulator, receiver
YPDSF_2977	COG2205	protein histidine kinase activity
YPDSF_2977	COG4999	Histidine kinase
YPDSF_2979	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YPDSF_2980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPDSF_2981	COG3956	TIGRFAM MazG family protein
YPDSF_2985	COG0602	queuosine metabolic process
YPDSF_2986	COG0720	synthase
YPDSF_2996	COG0529	Catalyzes the synthesis of activated sulfate
YPDSF_2999	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YPDSF_3004	COG1388	LysM domain
YPDSF_3004	COG4942	peptidase
YPDSF_3005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPDSF_3006	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YPDSF_3008	COG0698	ribose 5-phosphate isomerase
YPDSF_3009	COG1063	alcohol dehydrogenase
YPDSF_3010	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_3011	COG2376	Dihydroxyacetone kinase
YPDSF_3014	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPDSF_3017	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_3018	COG1858	cytochrome C peroxidase
YPDSF_3020	COG4771	TonB-dependent receptor
YPDSF_3026	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPDSF_3026	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPDSF_3027	COG1070	Carbohydrate kinase
YPDSF_3028	COG3623	hexulose-6-phosphate isomerase
YPDSF_3029	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_3030	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_3031	COG1129	ABC transporter
YPDSF_3033	COG1349	DNA-binding transcription factor activity
YPDSF_3034	COG0235	Class ii aldolase
YPDSF_3035	COG0243	molybdopterin cofactor binding
YPDSF_3036	COG0437	4 iron, 4 sulfur cluster binding
YPDSF_3037	COG3302	dmso reductase anchor subunit
YPDSF_3038	COG3381	protein complex oligomerization
YPDSF_3039	COG3038	cytochrome b561
YPDSF_3040	COG3783	Cytochrome b(562)
YPDSF_3044	COG1129	ABC transporter
YPDSF_3045	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_3046	COG3959	Transketolase, thiamine diphosphate binding domain
YPDSF_3047	COG3958	Transketolase
YPDSF_3048	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPDSF_3056	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YPDSF_3057	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPDSF_3058	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_3059	COG1238	metal cluster binding
YPDSF_3060	COG2918	glutathione biosynthetic process
YPDSF_3062	COG4536	flavin adenine dinucleotide binding
YPDSF_3063	COG4137	Cytochrome C assembly protein
YPDSF_3064	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPDSF_3070	COG3137	Salt-induced outer membrane protein
YPDSF_3071	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPDSF_3072	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPDSF_3073	COG3279	Response regulator of the LytR AlgR family
YPDSF_3074	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPDSF_3077	COG0494	nUDIX hydrolase
YPDSF_3082	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPDSF_3083	COG0849	cell division
YPDSF_3084	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPDSF_3088	COG0772	Belongs to the SEDS family
YPDSF_3091	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPDSF_3092	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPDSF_3093	COG0768	penicillin binding
YPDSF_3094	COG3116	cell division
YPDSF_3099	COG1609	Transcriptional regulator
YPDSF_3100	COG1943	Transposase
YPDSF_3102	COG0028	Belongs to the TPP enzyme family
YPDSF_3103	COG3328	transposase activity
YPDSF_3104	COG1022	Amp-dependent synthetase and ligase
YPDSF_3107	COG0473	3-isopropylmalate dehydrogenase activity
YPDSF_3110	COG2814	Major facilitator Superfamily
YPDSF_3112	COG4143	(ABC) transporter
YPDSF_3113	COG1178	ABC-type Fe3 transport system permease component
YPDSF_3115	COG0586	Pfam SNARE associated Golgi protein
YPDSF_3116	COG0417	DNA replication proofreading
YPDSF_3120	COG2885	chlorophyll binding
YPDSF_3120	COG3047	cAMP biosynthetic process
YPDSF_3127	COG3501	Rhs element vgr protein
YPDSF_3137	COG0564	pseudouridine synthase activity
YPDSF_3138	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPDSF_3140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPDSF_3141	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YPDSF_3147	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPDSF_3149	COG2966	Psort location CytoplasmicMembrane, score
YPDSF_3150	COG1280	lysine exporter protein (LysE YggA)
YPDSF_3151	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPDSF_3152	COG0505	Belongs to the CarA family
YPDSF_3155	COG1047	Peptidyl-prolyl cis-trans
YPDSF_3158	COG0196	riboflavin kinase activity
YPDSF_3160	COG0583	DNA-binding transcription factor activity
YPDSF_3164	COG1584	GPR1 FUN34 yaaH family protein
YPDSF_3167	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPDSF_3176	COG0745	RESPONSE REGULATOR receiver
YPDSF_3177	COG3045	CreA protein
YPDSF_3178	COG3708	Transcriptional regulator
YPDSF_3178	COG2207	Transcriptional regulator
YPDSF_3181	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPDSF_3182	COG0741	lytic transglycosylase activity
YPDSF_3185	COG2199	diguanylate cyclase activity
YPDSF_3186	COG2885	chlorophyll binding
YPDSF_3187	COG0488	(ABC) transporter
YPDSF_3192	COG0560	Phosphoserine phosphatase
YPDSF_3193	COG3726	membrane protein affecting hemolysin expression
YPDSF_3197	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPDSF_3198	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPDSF_3199	COG0084	hydrolase, TatD family'
YPDSF_3200	COG4667	esterase of the alpha-beta hydrolase superfamily
YPDSF_3202	COG2823	Periplasmic or secreted lipoprotein
YPDSF_3204	COG0456	acetyltransferase
YPDSF_3207	COG3706	GGDEF domain
YPDSF_3211	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_3212	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_3215	COG0859	PFAM glycosyl transferase family 9
YPDSF_3217	COG2390	Transcriptional regulator
YPDSF_3226	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_3226	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPDSF_3226	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_3227	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_3228	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_3229	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_3230	COG2207	Transcriptional regulator
YPDSF_3232	COG4269	membrane
YPDSF_3241	COG2963	transposase activity
YPDSF_3243	COG1401	restriction endodeoxyribonuclease activity
YPDSF_3248	COG0582	viral genome integration into host DNA
YPDSF_3249	COG0795	lipopolysaccharide-transporting ATPase activity
YPDSF_3250	COG0795	lipopolysaccharide-transporting ATPase activity
YPDSF_3252	COG2927	DNA polymerase III (CHI subunit)
YPDSF_3253	COG0525	valine-tRNA ligase activity
YPDSF_3255	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPDSF_3256	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YPDSF_3257	COG2731	YhcH YjgK YiaL family protein
YPDSF_3260	COG0601	transmembrane transport
YPDSF_3261	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPDSF_3262	COG0444	Belongs to the ABC transporter superfamily
YPDSF_3263	COG4608	Belongs to the ABC transporter superfamily
YPDSF_3266	COG2188	Transcriptional regulator
YPDSF_3267	COG3624	Phosphonate C-P lyase system protein PhnG
YPDSF_3268	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPDSF_3269	COG3626	phosphonate metabolism
YPDSF_3270	COG3627	carbon phosphorus lyase activity
YPDSF_3271	COG4107	phosphonate C-P lyase system protein PhnK
YPDSF_3272	COG4778	phosphonate C-P lyase system protein PhnL
YPDSF_3273	COG3454	Phosphonate metabolism
YPDSF_3274	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPDSF_3275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPDSF_3276	COG0702	epimerase
YPDSF_3279	COG3842	ATPase activity
YPDSF_3280	COG0395	ABC-type sugar transport system, permease component
YPDSF_3282	COG1653	transport
YPDSF_3286	COG3153	acetyltransferase
YPDSF_3292	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_3294	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPDSF_3297	COG0513	Belongs to the DEAD box helicase family
YPDSF_3300	COG2801	Transposase and inactivated derivatives
YPDSF_3302	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPDSF_3303	COG0058	SHG alpha-glucan phosphorylase activity
YPDSF_3305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
YPDSF_3308	COG3275	phosphorelay sensor kinase activity
YPDSF_3313	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPDSF_3314	COG2095	MarC family integral membrane protein
YPDSF_3318	COG3265	gluconokinase activity
YPDSF_3319	COG2610	gluconate transmembrane transporter activity
YPDSF_3320	COG1609	Transcriptional regulator
YPDSF_3321	COG1741	Belongs to the pirin family
YPDSF_3322	COG0745	RESPONSE REGULATOR receiver
YPDSF_3324	COG0191	fructose-bisphosphate aldolase activity
YPDSF_3326	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_3327	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_3331	COG2081	HI0933 family
YPDSF_3332	COG0306	phosphate transporter
YPDSF_3335	COG0589	response to stress
YPDSF_3339	COG0339	signal peptide processing
YPDSF_3341	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPDSF_3342	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPDSF_3343	COG3835	regulator
YPDSF_3345	COG2610	gluconate transmembrane transporter activity
YPDSF_3346	COG1929	Belongs to the glycerate kinase type-1 family
YPDSF_3351	COG1295	ribonuclease BN
YPDSF_3352	COG2134	cdp-diacylglycerol pyrophosphatase
YPDSF_3353	COG2982	Protein involved in outer membrane biogenesis
YPDSF_3354	COG2200	EAL domain
YPDSF_3355	COG1942	4-Oxalocrotonate Tautomerase
YPDSF_3356	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_3357	COG0612	Peptidase, M16
YPDSF_3362	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPDSF_3363	COG2200	EAL domain
YPDSF_3363	COG2199	diguanylate cyclase activity
YPDSF_3364	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPDSF_3365	COG4608	Belongs to the ABC transporter superfamily
YPDSF_3366	COG0444	Belongs to the ABC transporter superfamily
YPDSF_3367	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPDSF_3368	COG0601	transmembrane transport
YPDSF_3369	COG0747	negative chemotaxis
YPDSF_3370	COG2831	hemolysin activation secretion protein
YPDSF_3372	COG2271	Major facilitator Superfamily
YPDSF_3373	COG3851	Histidine kinase
YPDSF_3374	COG2197	response regulator
YPDSF_3375	COG2194	sulfuric ester hydrolase activity
YPDSF_3381	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YPDSF_3382	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPDSF_3383	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPDSF_3384	COG1739	Uncharacterized protein family UPF0029
YPDSF_3393	COG0805	protein transport
YPDSF_3395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPDSF_3399	COG1322	Protein conserved in bacteria
YPDSF_3400	COG0586	Pfam SNARE associated Golgi protein
YPDSF_3401	COG1966	Carbon starvation protein
YPDSF_3403	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YPDSF_3404	COG0412	Dienelactone hydrolase
YPDSF_3406	COG0583	DNA-binding transcription factor activity
YPDSF_3408	COG0679	Auxin Efflux Carrier
YPDSF_3409	COG0584	glycerophosphoryl diester phosphodiesterase
YPDSF_3421	COG0410	ABC transporter
YPDSF_3422	COG0411	ABC transporter
YPDSF_3423	COG4177	L-phenylalanine transmembrane transporter activity
YPDSF_3424	COG0559	Belongs to the binding-protein-dependent transport system permease family
YPDSF_3425	COG0683	leucine binding
YPDSF_3429	COG2177	Part of the ABC transporter FtsEX involved in
YPDSF_3430	COG2884	Cell division ATP-binding protein ftsE
YPDSF_3431	COG0552	protein localization to endoplasmic reticulum
YPDSF_3431	COG0552	protein localization to endoplasmic reticulum
YPDSF_3432	COG0742	ribosomal rna small subunit methyltransferase
YPDSF_3433	COG3776	membrane
YPDSF_3436	COG3714	YhhN family
YPDSF_3439	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPDSF_3441	COG0247	lactate metabolic process
YPDSF_3443	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPDSF_3444	COG0584	glycerophosphoryl diester phosphodiesterase
YPDSF_3446	COG0561	phosphatase activity
YPDSF_3447	COG2267	carboxylic ester hydrolase activity
YPDSF_3448	COG1280	lysine exporter protein (LysE YggA)
YPDSF_3449	COG1280	lysine exporter protein (LysE YggA)
YPDSF_3450	COG0514	ATP-dependent DNA helicase (RecQ)
YPDSF_3451	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPDSF_3452	COG2050	protein possibly involved in aromatic compounds catabolism
YPDSF_3454	COG0598	Magnesium transport protein CorA
YPDSF_3455	COG5564	TIM-barrel signal transduction protein
YPDSF_3456	COG5441	Belongs to the UPF0261 family
YPDSF_3458	COG0210	DNA helicase
YPDSF_3459	COG1011	Hydrolase
YPDSF_3460	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPDSF_3461	COG3159	Protein conserved in bacteria
YPDSF_3463	COG5567	small periplasmic lipoprotein
YPDSF_3465	COG3072	Adenylate cyclase
YPDSF_3468	COG1587	Uroporphyrinogen-III synthase
YPDSF_3469	COG2959	enzyme of heme biosynthesis
YPDSF_3470	COG3071	HemY protein
YPDSF_3472	COG1113	amino acid transport
YPDSF_3476	COG2244	polysaccharide biosynthetic process
YPDSF_3477	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPDSF_3478	COG0456	acetyltransferase
YPDSF_3479	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPDSF_3480	COG1088	dTDP-glucose 4,6-dehydratase activity
YPDSF_3481	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPDSF_3482	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPDSF_3483	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPDSF_3484	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPDSF_3485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPDSF_3486	COG3118	belongs to the thioredoxin family
YPDSF_3490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPDSF_3493	COG3121	Chaperone
YPDSF_3496	COG3121	Chaperone
YPDSF_3502	COG0583	DNA-binding transcription factor activity
YPDSF_3511	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPDSF_3512	COG3978	acetolactate synthase activity
YPDSF_3515	COG3085	chromosome segregation
YPDSF_3517	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_3518	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_3519	COG1129	ABC transporter
YPDSF_3520	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_3528	COG0678	peroxiredoxin activity
YPDSF_3528	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPDSF_3529	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPDSF_3534	COG1629	transport
YPDSF_3537	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YPDSF_3541	COG2801	Transposase and inactivated derivatives
YPDSF_3546	COG0195	Participates in both transcription termination and antitermination
YPDSF_3548	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPDSF_3550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPDSF_3551	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YPDSF_3553	COG1534	Rna-binding protein
YPDSF_3554	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPDSF_3555	COG2027	D-alanyl-D-alanine carboxypeptidase
YPDSF_3556	COG0745	RESPONSE REGULATOR receiver
YPDSF_3557	COG0642	Histidine kinase
YPDSF_3559	COG0697	spore germination
YPDSF_3562	COG0142	geranyltranstransferase activity
YPDSF_3564	COG3423	Transcriptional regulator
YPDSF_3568	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPDSF_3570	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPDSF_3571	COG2105	PFAM AIG2 family protein
YPDSF_3572	COG2911	Protein conserved in bacteria
YPDSF_3573	COG0729	surface antigen
YPDSF_3575	COG1253	flavin adenine dinucleotide binding
YPDSF_3577	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPDSF_3579	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_3581	COG0545	Peptidyl-prolyl cis-trans isomerase
YPDSF_3582	COG3061	Opacity-associated protein A
YPDSF_3584	COG1943	Transposase
YPDSF_3586	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPDSF_3588	COG1073	alpha beta
YPDSF_3591	COG3650	response to hydrogen peroxide
YPDSF_3592	COG1960	acyl-CoA dehydrogenase activity
YPDSF_3593	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPDSF_3594	COG0557	exoribonuclease II activity
YPDSF_3597	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPDSF_3598	COG0330	HflC and HflK could
YPDSF_3599	COG0330	HflC and HflK could
YPDSF_3600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPDSF_3604	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPDSF_3605	COG0802	atpase or kinase
YPDSF_3606	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPDSF_3606	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPDSF_3607	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPDSF_3608	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YPDSF_3612	COG1511	domain protein
YPDSF_3612	COG3264	Mechanosensitive ion channel
YPDSF_3614	COG1053	succinate dehydrogenase
YPDSF_3615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPDSF_3617	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPDSF_3618	COG2076	Multidrug Resistance protein
YPDSF_3626	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPDSF_3629	COG3383	formate dehydrogenase (NAD+) activity
YPDSF_3630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_3631	COG0493	'glutamate synthase
YPDSF_3631	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_3632	COG1309	transcriptional regulator
YPDSF_3645	COG1454	alcohol dehydrogenase
YPDSF_3647	COG0629	single-stranded DNA binding
YPDSF_3648	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPDSF_3649	COG2315	Protein conserved in bacteria
YPDSF_3650	COG1448	Aminotransferase
YPDSF_3651	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPDSF_3652	COG0305	Participates in initiation and elongation during chromosome replication
YPDSF_3655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPDSF_3656	COG0735	belongs to the Fur family
YPDSF_3658	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPDSF_3667	COG3121	Chaperone
YPDSF_3679	COG1358	cellular component organization or biogenesis
YPDSF_3684	COG3721	Heme iron utilization protein
YPDSF_3685	COG0702	epimerase
YPDSF_3687	COG4771	TonB-dependent receptor
YPDSF_3688	COG3720	iron ion transport
YPDSF_3689	COG4558	Periplasmic binding protein
YPDSF_3690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_3692	COG0626	cystathionine gamma-synthase activity
YPDSF_3693	COG0814	amino acid
YPDSF_3694	COG0583	DNA-binding transcription factor activity
YPDSF_3695	COG0425	Belongs to the sulfur carrier protein TusA family
YPDSF_3696	COG2391	methyltransferase activity
YPDSF_3717	COG1301	dicarboxylic acid transport
YPDSF_3719	COG3162	membrane
YPDSF_3724	COG2801	Transposase and inactivated derivatives
YPDSF_3727	COG0151	Belongs to the GarS family
YPDSF_3730	COG3068	Protein conserved in bacteria
YPDSF_3731	COG1515	deoxyribonuclease V activity
YPDSF_3736	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YPDSF_3738	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPDSF_3750	COG0250	Participates in transcription elongation, termination and antitermination
YPDSF_3751	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPDSF_3759	COG2986	histidine ammonia-lyase
YPDSF_3762	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YPDSF_3765	COG4607	ABC-type enterochelin transport system periplasmic component
YPDSF_3767	COG4605	iron ion homeostasis
YPDSF_3768	COG4604	ABC transporter, ATP-binding protein
YPDSF_3775	COG0582	viral genome integration into host DNA
YPDSF_3776	COG2207	Transcriptional regulator
YPDSF_3776	COG1609	Transcriptional regulator
YPDSF_3777	COG4214	carbohydrate transport
YPDSF_3779	COG4213	ABC transporter substrate-binding protein
YPDSF_3781	COG1070	Carbohydrate kinase
YPDSF_3783	COG3121	Chaperone
YPDSF_3784	COG3188	usher protein
YPDSF_3785	COG3188	usher protein
YPDSF_3787	COG3274	enterobacterial common antigen metabolic process
YPDSF_3789	COG2801	Transposase and inactivated derivatives
YPDSF_3791	COG0527	aspartate kinase activity
YPDSF_3791	COG0460	homoserine dehydrogenase
YPDSF_3792	COG0626	cystathionine gamma-synthase activity
YPDSF_3795	COG4682	membrane
YPDSF_3797	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPDSF_3798	COG1609	Transcriptional regulator
YPDSF_3799	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPDSF_3802	COG1575	Belongs to the MenA family. Type 1 subfamily
YPDSF_3812	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPDSF_3813	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPDSF_3814	COG1494	fructose-1,6-bisphosphatase
YPDSF_3816	COG3152	Membrane
YPDSF_3819	COG0583	DNA-binding transcription factor activity
YPDSF_3820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPDSF_3821	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPDSF_3825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPDSF_3830	COG4974	Belongs to the 'phage' integrase family
YPDSF_3831	COG3678	ATP-independent chaperone mediated protein folding
YPDSF_3832	COG0745	RESPONSE REGULATOR receiver
YPDSF_3833	COG2205	protein histidine kinase activity
YPDSF_3834	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPDSF_3834	COG2169	Transcriptional regulator
YPDSF_3835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPDSF_3836	COG1045	serine acetyltransferase
YPDSF_3839	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPDSF_3840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPDSF_3842	COG4942	peptidase
YPDSF_3843	COG2861	carbohydrate metabolic process
YPDSF_3844	COG2861	carbohydrate metabolic process
YPDSF_3846	COG0156	8-amino-7-oxononanoate synthase activity
YPDSF_3848	COG0859	PFAM glycosyl transferase family 9
YPDSF_3849	COG0859	PFAM glycosyl transferase family 9
YPDSF_3850	COG1519	Transferase
YPDSF_3854	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YPDSF_3857	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPDSF_3862	COG1561	YicC-like family, N-terminal region
YPDSF_3863	COG2860	membrane
YPDSF_3864	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YPDSF_3867	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPDSF_3868	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPDSF_3869	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPDSF_3870	COG0786	glutamate:sodium symporter activity
YPDSF_3871	COG2233	PERMEase
YPDSF_3872	COG2982	Protein involved in outer membrane biogenesis
YPDSF_3873	COG0456	acetyltransferase
YPDSF_3877	COG1295	ribonuclease BN
YPDSF_3878	COG1011	Hydrolase
YPDSF_3880	COG0174	glutamine synthetase
YPDSF_3881	COG3852	Histidine kinase
YPDSF_3883	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPDSF_3886	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPDSF_3886	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPDSF_3887	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPDSF_3888	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPDSF_3889	COG3084	Protein conserved in bacteria
YPDSF_3891	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPDSF_3892	COG3328	transposase activity
YPDSF_3893	COG2186	Transcriptional regulator
YPDSF_3894	COG0477	Major facilitator Superfamily
YPDSF_3903	COG1522	sequence-specific DNA binding
YPDSF_3904	COG0716	FMN binding
YPDSF_3907	COG3312	ion transport
YPDSF_3917	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YPDSF_3918	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPDSF_3919	COG0573	inorganic phosphate transmembrane transporter activity
YPDSF_3920	COG0581	inorganic phosphate transmembrane transporter activity
YPDSF_3922	COG0704	Plays a role in the regulation of phosphate uptake
YPDSF_3924	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_3925	COG0765	amino acid transport
YPDSF_3926	COG0765	amino acid transport
YPDSF_3927	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_3928	COG2252	PERMEase
YPDSF_3932	COG0706	membrane insertase activity
YPDSF_3935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPDSF_3944	COG0515	serine threonine protein kinase
YPDSF_3947	COG2801	Transposase and inactivated derivatives
YPDSF_3948	COG4372	Transposase
YPDSF_3955	COG2801	Transposase and inactivated derivatives
YPDSF_3956	COG2963	transposase activity
YPDSF_3957	COG5599	Phosphatase
YPDSF_3958	COG1317	bacterial-type flagellum organization
YPDSF_3960	COG4669	(LipO)protein
YPDSF_3969	COG2207	Transcriptional regulator
YPDSF_3970	COG4792	protein secretion
YPDSF_3971	COG4791	protein targeting
YPDSF_3972	COG4794	Type iii secretion
YPDSF_3973	COG4790	Type iii secretion
YPDSF_3974	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPDSF_3983	COG4789	Type iii secretion
YPDSF_3987	COG0457	Tetratricopeptide repeat
YPDSF_3990	COG3328	transposase activity
YPDSF_3996	COG4886	Leucine-rich repeat (LRR) protein
YPDSF_4001	COG3177	Filamentation induced by cAMP protein fic
YPDSF_4002	COG2801	Transposase and inactivated derivatives
YPDSF_4005	COG2801	Transposase and inactivated derivatives
YPDSF_4008	COG1192	Involved in chromosome partitioning
YPDSF_4009	COG1475	DNA binding
YPDSF_4011	COG3609	addiction module antidote protein, CC2985 family
YPDSF_4013	COG5599	Phosphatase
YPDSF_4015	COG2801	Transposase and inactivated derivatives
YPDSF_4019	COG2801	Transposase and inactivated derivatives
YPDSF_4023	COG2801	Transposase and inactivated derivatives
YPDSF_4031	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
YPDSF_4032	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPDSF_4032	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPDSF_4039	COG3941	tape measure
YPDSF_4058	COG1475	DNA binding
YPDSF_4059	COG1475	DNA binding
YPDSF_4060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPDSF_4068	COG1943	Transposase
YPDSF_4070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPDSF_4071	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPDSF_4075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPDSF_4084	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YPDSF_4086	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPDSF_4104	COG3328	transposase activity
YPDSF_4123	COG3328	transposase activity
YPDSF_4128	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YPDSF_4128	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPDSF_4133	COG3344	reverse transcriptase
YPDSF_4135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPDSF_4149	COG1475	DNA binding