locus-tag class description CH43_1 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CH43_10 ENOG41077RS Phosphatase CH43_100 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein CH43_1000 ENOG4105WSB biofilm stress and motility protein A CH43_1003 ENOG4105DIJ Phosphoethanolamine transferase CH43_1004 ENOG4108KX4 response regulator CH43_1005 ENOG4105BZU Histidine kinase CH43_1006 ENOG4105CXY transporter CH43_101 ENOG4105EIN peptidylprolyl cis-trans isomerase CH43_1010 ENOG4105D5K Hemolysin activator protein CH43_1012 ENOG4105DEF Extracellular solute-binding protein, family 5 CH43_1013 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH43_1014 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH43_1015 ENOG4105C3U ABC transporter CH43_1016 ENOG4108JQ7 (ABC) transporter CH43_1017 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) CH43_1018 ENOG4105BZU Histidine kinase CH43_1019 ENOG4108PU9 oligogalacturonate-specific porin CH43_102 ENOG4108RS6 transposase CH43_1024 ENOG4105CS0 peptidase CH43_1025 ENOG4107SS6 2-dehydro-3-deoxygluconokinase CH43_1026 ENOG4105VSH 4-oxalocrotonate tautomerase CH43_1027 ENOG4105CMB EAL domain-containing protein CH43_1028 ENOG41066T0 asmA family CH43_1029 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) CH43_1030 ENOG4107H3J ribonuclease CH43_1035 ENOG4105BZW Glycerate kinase CH43_1036 ENOG4107QQ0 gntp family CH43_1037 ENOG4107VHA regulatoR CH43_1038 ENOG4105DC8 reductase CH43_1039 ENOG4105D6S protein involved in catabolism of external DNA CH43_104 ENOG4105K70 DNA-binding protein CH43_1040 ENOG4105DGW oligopeptidase A CH43_1044 ENOG4108M6U Universal stress protein A CH43_1047 ENOG4105CJ3 phosphate transporter CH43_1048 ENOG4105CBX hi0933 family CH43_105 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) CH43_1051 ENOG4105CNN ABC, transporter CH43_1052 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH43_1054 ENOG4105D2N Aldolase CH43_1056 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH43_1058 ENOG4105C2I pirin domain protein CH43_1061 ENOG4105C6Z Gluconate CH43_1062 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CH43_1066 ENOG41076UM multiple antibiotic resistance (MarC)-related protein CH43_1067 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CH43_1073 ENOG4108HRK Histidine kinase CH43_1078 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CH43_1079 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CH43_1082 ENOG4105DQ6 Transposase CH43_1086 ENOG4105C1J atp-dependent rna helicase CH43_1089 ENOG4105DEN Luciferase family CH43_1092 ENOG4105BZS acriflavin resistance protein CH43_1093 ENOG4105ENJ RND efflux system, outer membrane lipoprotein CH43_1094 ENOG4106RZ4 Peptidase U32 CH43_1095 ENOG4105CFP Peptidase U32 CH43_1096 ENOG4105XPQ lipid carrier protein CH43_1097 ENOG4108YYD acetyltransferase CH43_11 ENOG4105E8V Alpha Beta Hydrolase Fold protein CH43_110 ENOG4105M85 Bola protein CH43_1102 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component CH43_1103 ENOG4105DRS transport system, permease CH43_1107 ENOG4105K4T epimerase CH43_1108 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein CH43_1109 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) CH43_111 ENOG4105IEY (LipO)protein CH43_1110 ENOG4105FD8 phosphonate metabolism protein PhnM CH43_1111 ENOG4105HRV phosphonate c-p lyase system protein phnl CH43_1112 ENOG4105ENV phosphonate C-P lyase system protein PhnK CH43_1113 ENOG4105FT8 Phosphonate metabolism CH43_1114 ENOG4105EKV Phosphonate metabolism protein CH43_1115 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH CH43_1116 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG CH43_1117 ENOG4107RJJ Transcriptional regulator CH43_1119 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) CH43_112 ENOG4105EYM Major Facilitator superfamily CH43_1120 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CH43_1121 ENOG4108JQ7 (ABC) transporter CH43_1122 ENOG4105C3U ABC transporter CH43_1123 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH43_1124 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH43_1127 ENOG4105XEP YhcH YjgK YiaL family protein CH43_1128 ENOG4105DBV ornithine carbamoyltransferase CH43_1129 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) CH43_113 ENOG4108NFH Sugar hydrolase CH43_1130 ENOG4108MJ3 acetyltransferase CH43_1131 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) CH43_1132 ENOG4105MYG DNA polymerase iii, chi subunit CH43_1134 ENOG4108M8S permease YjgP YjgQ family protein CH43_1135 ENOG4108K5H permease YjgP YjgQ family protein CH43_1139 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) CH43_114 ENOG4105E2S oxidase) subunit II CH43_1142 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 CH43_115 ENOG4105BZ9 Cytochrome C oxidase, subunit I CH43_1154 ENOG4108M3P Membrane CH43_1156 ENOG4108XCZ PTS System CH43_1157 ENOG4106R3P AraC family transcriptional regulator CH43_1158 ENOG4108YRF PTS System CH43_1159 ENOG4105DM4 PTS System CH43_116 ENOG4105CCU oxidase (Subunit III) CH43_1160 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CH43_1161 ENOG4105RI1 glycoprotein receptor CH43_1168 ENOG4105DKT Transcriptional regulator CH43_117 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) CH43_1170 ENOG4105DKP glycosyl transferase, family 9 CH43_1173 ENOG410624X efflux transporter, rnd family, mfp subunit CH43_1174 ENOG4105BZS acriflavin resistance protein CH43_1177 ENOG4105BZU Histidine kinase CH43_1178 ENOG4105YBH Protein of unknown function (DUF1435) CH43_1181 ENOG4108WPU DNA polymerase III subunit psi CH43_1182 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CH43_1184 ENOG4105K3G Periplasmic Protein CH43_1186 ENOG4108NRW Phospholipase, patatin family CH43_1187 ENOG4105EYA deoxyribonuclease CH43_1188 ENOG4105D9N nucleoside CH43_1189 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH43_119 ENOG4107RDB Major Facilitator CH43_1193 ENOG41062Z9 Membrane CH43_1194 ENOG4105EAC phosphoserine phosphatase CH43_1195 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CH43_1196 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase CH43_1199 ENOG4105C5H ABC transporter CH43_1200 ENOG41090EK ompa motb domain protein CH43_1201 ENOG4108KHX Diguanylate cyclase CH43_1204 ENOG4107SC1 transglycosylase CH43_1206 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) CH43_1207 ENOG4105UEI Transcriptional Regulator AraC Family CH43_121 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CH43_1210 ENOG4108RH0 Crea protein CH43_1211 ENOG41065U4 response regulator CH43_1219 ENOG4108RIR Molybdenum cofactor biosynthesis protein CH43_122 ENOG4107S0N DJ-1 family CH43_1222 ENOG4106HK8 GPR1 FUN34 yaaH family protein CH43_1226 ENOG41063Z6 transcriptional regulator, lysR family CH43_1228 ENOG4105DTN riboflavin biosynthesis protein ribF CH43_1231 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase CH43_1234 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CH43_1235 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CH43_1236 ENOG4105N14 lysine exporter protein LysE YggA CH43_1237 ENOG4105DWK Membrane CH43_1239 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) CH43_1244 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) CH43_1245 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) CH43_1247 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) CH43_1248 ENOG4105D3G Pseudouridine synthase CH43_125 ENOG4105CTB Polyprenyl synthetase CH43_1257 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH43_1258 ENOG4105CS6 Rhs element vgr protein CH43_1269 ENOG4105CQ2 DNA polymerase CH43_1270 ENOG4108KF1 Membrane CH43_1272 ENOG4106SMU thiamine transporter membrane protein CH43_1273 ENOG4105DP9 ABC transporter CH43_1276 ENOG4105S8Q sugar efflux transporter CH43_1279 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CH43_128 ENOG4108ZAI phosphatidylglycerophosphatase a CH43_1282 ENOG41064T2 transcriptional regulator, lysR family CH43_1283 ENOG4108IQE Amp-dependent synthetase and ligase CH43_1285 ENOG4105C7K acetolactate synthase CH43_1286 ENOG4108ZP8 Acetolactate synthase small subunit CH43_1287 ENOG4108RS6 transposase CH43_1288 ENOG4107B7Y DNA-binding transcriptional regulator FruR CH43_129 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CH43_1290 ENOG4108RNS Exports L-alanine (By similarity) CH43_1293 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) CH43_1294 ENOG4105CJN penicillin-binding protein CH43_1295 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CH43_1296 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) CH43_1299 ENOG4105CNI cell division protein FtsW CH43_13 ENOG4108HPI phosphatidate Cytidylyltransferase CH43_1303 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) CH43_1304 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CH43_1305 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CH43_1310 ENOG4105M6F mutator MutT protein CH43_1315 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CH43_1317 ENOG4105D7Q type ii secretion system CH43_1318 ENOG4107QHF type ii secretion system protein e CH43_1319 ENOG4108ZUW Major pilin subunit CH43_132 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CH43_1320 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CH43_1321 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH43_1322 ENOG4106A72 regulatory protein AmpE CH43_1323 ENOG4105C85 amino acid CH43_1324 ENOG41073TP transcriptional regulator CH43_1325 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CH43_1326 ENOG4107QSN dihydrolipoamide acetyltransferase CH43_1327 ENOG4107QN2 dihydrolipoyl dehydrogenase CH43_1328 ENOG4108RS6 transposase CH43_1329 ENOG4107QIJ Aconitate hydratase 2 CH43_1331 ENOG4105RPH Inner membrane protein YddG CH43_1334 ENOG4108ZRK uncharacterized protein yacC CH43_1335 ENOG4105E3B Multicopper oxidase CH43_1336 ENOG4108UGV hypoxanthine phosphoribosyltransferase CH43_1337 ENOG41077A9 carbonic anhydrase CH43_1338 ENOG4105DA5 (ABC) transporter CH43_1339 ENOG4105E3A (ABC) transporter CH43_1341 ENOG4107BJW polysaccharide deacetylase CH43_1345 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CH43_1346 ENOG4105DJ0 Poly(A) Polymerase CH43_1347 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) CH43_1348 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters CH43_1350 ENOG4107XID 2'-5' rna ligase CH43_1351 ENOG4105CQ7 ATP-dependent helicase CH43_1352 ENOG4105BZ4 penicillin-binding protein CH43_1353 ENOG4105E0A ABC, transporter CH43_1354 ENOG4105J76 Periplasmic binding protein CH43_1355 ENOG4105S6R Iron-hydroxamate transporter permease subunit CH43_1359 ENOG4105EN6 Membrane CH43_1361 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) CH43_1363 ENOG4105C0H protease CH43_1364 ENOG4105BZU Histidine kinase CH43_1365 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CH43_1366 ENOG4105DXN mazG family CH43_137 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CH43_1370 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CH43_1371 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CH43_138 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CH43_1382 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) CH43_1383 ENOG4105N0Z inner membrane protein ygbE CH43_1385 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) CH43_139 ENOG4105VIE preprotein translocase, subunit YajC CH43_1390 ENOG4108K5P (LipO)protein CH43_1391 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH43_1392 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) CH43_1393 ENOG4108YZG isomerase CH43_1394 ENOG4105CPQ Dehydrogenase CH43_1395 ENOG4105CHR reductase CH43_1396 ENOG4105CMT Dihydroxyacetone kinase CH43_1398 ENOG4105DKT Transcriptional regulator CH43_14 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase CH43_1403 ENOG4105E89 ABC transporter CH43_1404 ENOG4105CA0 peroxidase CH43_1406 ENOG4105D05 Receptor CH43_1408 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CH43_141 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) CH43_1410 ENOG4107GFK fumarate CH43_1411 ENOG4105CMG Carbohydrate kinase CH43_1412 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase CH43_1413 ENOG4105F5R ABC transporter CH43_1414 ENOG4105CNN ABC, transporter CH43_1415 ENOG4105C2J ABC transporter CH43_1417 ENOG4105E98 transcriptional regulator DeoR family CH43_1418 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CH43_1419 ENOG4107QY8 reductase CH43_142 ENOG4108ZYK Acyl carrier protein phosphodiesterase CH43_1420 ENOG4105QAX Iron-sulfur CH43_1421 ENOG4107KGK dmso reductase anchor subunit CH43_1422 ENOG4108NEM leader-binding protein dmsD CH43_1423 ENOG4105CPW cytochrome b561 CH43_1424 ENOG4108XVM Cytochrome b(562) CH43_1428 ENOG4105C2J ABC transporter CH43_1429 ENOG4105CNN ABC, transporter CH43_143 ENOG4105D3R alkyl hydroperoxide reductase CH43_1430 ENOG4108HHA Transketolase CH43_1431 ENOG4108IUS Transketolase CH43_1432 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CH43_1439 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CH43_1440 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) CH43_1444 ENOG4107VXZ Hydrolase CH43_1445 ENOG4105W39 Membrane CH43_1446 ENOG4105D9M gamma-glutamylcysteine synthetase CH43_1448 ENOG4108JU6 CBS domain protein CH43_1449 ENOG4106KVJ cytochrome C assembly protein CH43_1450 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CH43_1455 ENOG4108NE3 Salt-induced outer membrane protein CH43_1456 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH43_1457 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH43_1458 ENOG4108NEV two component transcriptional regulator, LytTR family CH43_1459 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH43_146 ENOG4105CHR reductase CH43_1463 ENOG4105EHE chorismate mutase- prephenate dehydrogenase CH43_1466 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA CH43_1467 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane CH43_1468 ENOG4105C34 Pseudouridine synthase CH43_1469 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CH43_147 ENOG4107R28 alpha amylase, catalytic region CH43_1470 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH43_148 ENOG4105C85 amino acid CH43_1481 ENOG4107QP3 malate synthase g CH43_1482 ENOG4108I9X Isocitrate lyase CH43_1484 ENOG41069M3 Transcriptional regulator CH43_1485 ENOG4105C3R Methionine synthase CH43_1489 ENOG4105CFH Aspartokinase CH43_149 ENOG4105CWM branched-chain amino acid transport system II carrier protein CH43_1492 ENOG4105EG2 ABC transporter, permease CH43_1493 ENOG4105D56 permease protein CH43_1494 ENOG4107FKK extracellular solute-binding protein family 1 CH43_1498 ENOG4107W52 maltose operon periplasmic protein CH43_1500 ENOG4108WC9 type VI secretion system effector, hcp1 family CH43_1504 ENOG4105DQ6 Transposase CH43_151 ENOG4105BZU Histidine kinase CH43_1513 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH43_152 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CH43_1520 ENOG4105CS6 Rhs element vgr protein CH43_1523 ENOG4105CNA YD repeat protein CH43_1529 ENOG4105CS6 Rhs element vgr protein CH43_153 ENOG4107RH8 nuclease SbcCD subunit D CH43_1531 ENOG4105CNA YD repeat protein CH43_1534 ENOG4107TYG Oxidoreductase domain-containing protein CH43_1535 ENOG4105W4W Transcriptional regulator CH43_1536 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) CH43_1537 ENOG4108RVA ribokinase CH43_1538 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH43_154 ENOG4105EYH Exonuclease CH43_1540 ENOG4105GVF (ABC) transporter CH43_1542 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CH43_1545 ENOG4105C7N Xanthine uracil vitamin C permease CH43_1546 ENOG4105EEQ Na H antiporter CH43_1548 ENOG4105D1S lipid A biosynthesis CH43_155 ENOG4105DKQ ROK family CH43_1550 ENOG4105C2J ABC transporter CH43_1551 ENOG4105CNN ABC, transporter CH43_1553 ENOG4105EF1 ribulokinase CH43_1554 ENOG4105C2X Arabinose 5-phosphate isomerase CH43_1555 ENOG4105CYM Glutathione S-transferase CH43_1558 ENOG4108RS6 transposase CH43_1559 ENOG4105VEQ Cold shock protein CH43_1560 ENOG4105VEQ Cold shock protein CH43_1561 ENOG4108XTF Outer Membrane Lipoprotein CH43_1564 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase CH43_1565 ENOG4105CSH Transporter CH43_1568 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) CH43_1569 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CH43_1571 ENOG4108IA2 Sodium pantothenate symporter CH43_1572 ENOG4105RG0 Membrane CH43_1574 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CH43_1575 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein CH43_1578 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) CH43_1579 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CH43_1580 ENOG41062P1 Diguanylate cyclase phosphodiesterase CH43_1581 ENOG4105DFF Rod shape-determining protein mreb CH43_1582 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CH43_1583 ENOG4105VQ7 Rod shape-determining protein MreD CH43_1585 ENOG4105C03 ribonuclease CH43_1586 ENOG4105QD6 exported protein CH43_1588 ENOG4105D1U peptidase U62 modulator of DNA gyrase CH43_1598 ENOG4105CR8 Transcriptional regulator CH43_160 ENOG4105F2W methyltransferase CH43_1602 ENOG4105C26 Dehydrogenase CH43_1605 ENOG4105UNR (Barnase) inhibitor CH43_1607 ENOG4105CMS peptidase U62, modulator of DNA gyrase CH43_1609 ENOG4108XVM Cytochrome b(562) CH43_1610 ENOG4105NXH GreA GreB family elongation factor CH43_1611 ENOG4105CG3 alpha amylase, catalytic region CH43_1612 ENOG4105C5Y PTS System CH43_1613 ENOG4105D4X repressor CH43_1615 ENOG4105KME endoribonuclease L-psp CH43_1618 ENOG41080Z8 PHOSPHOCARRIER protein CH43_1620 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN CH43_1621 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA CH43_1622 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH43_1623 ENOG4108IUZ ABC transporter CH43_1624 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA CH43_1625 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) CH43_1626 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase CH43_1627 ENOG4105C2X Arabinose 5-phosphate isomerase CH43_1628 ENOG4105FEU K -dependent Na -Ca exchanger CH43_1629 ENOG4105DHJ ABC, transporter CH43_1630 ENOG4105CY3 ABC transporter, permease CH43_1631 ENOG4107PE3 Mammalian cell entry related domain protein CH43_1632 ENOG4105E3I toluene tolerance CH43_1633 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane CH43_1634 ENOG4105VFK BolA family CH43_1636 ENOG4105C0H protease CH43_1637 ENOG4108RS6 transposase CH43_1638 ENOG4105C0H protease CH43_1639 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III CH43_1640 ENOG4105D6Z AFG1 family ATPase CH43_1643 ENOG4107MKT Stringent starvation protein a CH43_1644 ENOG4105KB2 stringent starvation protein b CH43_1646 ENOG4105BZ8 glutamate synthase CH43_1647 ENOG4105CBC glutamate synthase CH43_1648 ENOG4105N5T Radical SAM Protein CH43_1649 ENOG4105BZU Histidine kinase CH43_1650 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain CH43_1652 ENOG4105W4M Transport-associated protein CH43_1656 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CH43_1657 ENOG4108CNN domain protein CH43_1658 ENOG4105CWB LysR family transcriptional Regulator CH43_1659 ENOG4105CHF Glutathione S-transferase CH43_1660 ENOG4108VBZ doxx family CH43_1662 ENOG41090KG Inner membrane protein YqjE CH43_1663 ENOG4105NE1 Conserved Protein CH43_1666 ENOG4106W5V Membrane CH43_1672 ENOG4107QZW Altronate oxidoreductase CH43_1673 ENOG4105CTX dehydratase CH43_1674 ENOG4105P66 Membrane CH43_1675 ENOG4108RS6 transposase CH43_1678 ENOG4105EE0 oxidoreductase CH43_1679 ENOG4108VKG metal-dependent hydrolase CH43_1682 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CH43_1683 ENOG4108YK4 Acid-resistance membrane protein CH43_1686 ENOG4108M24 von Willebrand factor, type A CH43_1689 ENOG4108M24 von Willebrand factor, type A CH43_1690 ENOG4105D5K Hemolysin activator protein CH43_1691 ENOG4105CKT filamentous hemagglutinin CH43_1693 ENOG4105CKT filamentous hemagglutinin CH43_1695 ENOG4105CKT filamentous hemagglutinin CH43_1700 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 CH43_1701 ENOG4107KJX Transcriptional regulator CH43_1702 ENOG4108IJG ABC transporter substrate-binding protein CH43_1704 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component CH43_1706 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CH43_1708 ENOG4108MI0 Resistance protein CH43_1709 ENOG4105J12 Multidrug resistance protein mdtN CH43_171 ENOG4105CIN aminoacyl-histidine dipeptidase CH43_1712 ENOG4105CHM Aminotransferase CH43_1716 ENOG4105KME endoribonuclease L-psp CH43_1734 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH43_1735 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CH43_1736 ENOG4105VCC 30S ribosomal protein S21 CH43_1739 ENOG4107ZVW dihydroneopterin aldolase CH43_1742 ENOG4106MWK domain protein CH43_1743 ENOG4105I7R Adenylate cyclase CH43_1746 ENOG4105DVH amino acid CH43_1747 ENOG4105W0Z cytoplasmic protein CH43_175 ENOG4105CJ2 (LipO)protein CH43_1750 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CH43_1751 ENOG4106032 Glutathionylspermidine synthase CH43_1754 ENOG4105DFG type I secretion outer membrane protein CH43_1755 ENOG41087AY ADP-Ribose pyrophosphatase CH43_1756 ENOG4108SX3 cytoplasmic protein CH43_1757 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) CH43_1758 ENOG4105IPS esterase CH43_1759 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH43_1760 ENOG4105CR8 Transcriptional regulator CH43_1761 ENOG4105NF4 modulator of drug activity CH43_1762 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH43_1763 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase CH43_1764 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CH43_1767 ENOG4105CV8 reductase CH43_1768 ENOG4108I6A alcohol dehydrogenase CH43_1769 ENOG4105CF7 AraC family transcriptional regulator CH43_1770 ENOG4108K81 inner membrane protein YghB CH43_1771 ENOG4105C28 cystathionine CH43_1772 ENOG4105CWK Biopolymer transport protein, ExbB CH43_1774 ENOG4108ZZF transport protein (ExbD) CH43_1789 ENOG4106PG1 outer membrane usher protein CH43_179 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH43_1790 ENOG4106P2F Pfam:Pili_assembly_C CH43_1793 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein CH43_1797 ENOG4105D00 flagellar biosynthetic protein flhB CH43_1798 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CH43_1799 ENOG4105VS8 Flagellar biosynthetic protein fliq CH43_180 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH43_1800 ENOG4105CN7 Flagellar biosynthetic protein FliP CH43_1801 ENOG4105DD5 Flagellar motor switch protein CH43_1803 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH43_1805 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CH43_1808 ENOG4108JIR Flagellum-specific ATP synthase CH43_181 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH43_1812 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA CH43_1813 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CH43_1814 ENOG4108ZC9 flagellar basal-body rod protein flgc CH43_1815 ENOG4105W00 Flagellar hook capping protein CH43_1816 ENOG4105BZE flagellar hook protein, FlgE CH43_1817 ENOG4108KPB Flagellar basal-body rod protein FlgF CH43_1818 ENOG4105CGA flagellar basal-body rod protein FlgG CH43_1819 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CH43_182 ENOG4105E7A Glutamine amidotransferase CH43_1820 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CH43_1822 ENOG4105E1Q flagellar hook-associated protein CH43_1826 ENOG4108M3R transcriptional activator CadC CH43_183 ENOG4105F7V ErfK ybiS ycfS ynhG family protein CH43_1831 ENOG410804A Flagellar hook-associated 2 domain-containing protein CH43_1837 ENOG4107RD7 Flagellar Motor Protein, MotA CH43_1842 ENOG4108XTF Outer Membrane Lipoprotein CH43_1845 ENOG4105DQ6 Transposase CH43_1846 ENOG4105CT4 transporter CH43_1848 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CH43_1849 ENOG4105DUU IucA IucC family protein CH43_185 ENOG4107QPN acyl-Coa dehydrogenase CH43_1868 ENOG4105CDV Ompa motb domain protein CH43_1870 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH43_1879 ENOG4105CXN decarboxylase CH43_188 ENOG4106YJS accessory processing protein CH43_1880 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH43_1881 ENOG4105C2J ABC transporter CH43_1882 ENOG4105CNN ABC, transporter CH43_1887 ENOG4105CEN a g-specific adenine glycosylase CH43_1889 ENOG41090ED Protein with unknown function (DUF469) CH43_1890 ENOG4105CSV Glutaminase CH43_1891 ENOG4105K33 Periplasmic Protein CH43_1892 ENOG4105K33 Periplasmic Protein CH43_1893 ENOG4105EUK rtx toxin RtxA CH43_1894 ENOG4105CSA Coproporphyrinogen iii oxidase CH43_1895 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) CH43_1897 ENOG4108VIA integral membrane protein CH43_1898 ENOG4105II7 pyrroline-5-carboxylate reductase CH43_1899 ENOG4105DFA alanine racemase domain protein CH43_1900 ENOG4105CZX twitching motility protein CH43_1902 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) CH43_1905 ENOG4105D7Z glutathione synthase CH43_1906 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CH43_1907 ENOG4105RWS endonuclease I CH43_1911 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) CH43_1913 ENOG4108K0D peptidase, M48 CH43_1914 ENOG4105CV1 Transketolase (EC 2.2.1.1) CH43_1918 ENOG4105D2N Aldolase CH43_1919 ENOG4105D64 Mechanosensitive ion channel CH43_1921 ENOG4105MPN Membrane CH43_1923 ENOG4105E66 phosphoriboisomerase A CH43_1924 ENOG4108JQ1 Dehydrogenase CH43_1925 ENOG4108RS6 transposase CH43_1926 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CH43_1929 ENOG4107RAQ aminopeptidase CH43_1930 ENOG4105D0A hydroxylase CH43_1931 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CH43_1939 ENOG4108UT2 hemolysin iii CH43_1942 ENOG4105Y75 tpr repeat protein CH43_1943 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH43_1944 ENOG4105EB3 Histidine kinase CH43_1945 ENOG4105CT7 inner membrane cred family protein CH43_1946 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) CH43_1947 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CH43_1948 ENOG4105T95 Thiol disulfide interChange protein CH43_1949 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CH43_1953 ENOG4105DFP Integrase CH43_1957 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation CH43_1958 ENOG4105WJ3 XRE family Transcriptional regulator CH43_196 ENOG4105CHM Aminotransferase CH43_1975 ENOG4105NTW Transcriptional regulator CH43_1976 ENOG4108UY0 (LipO)protein CH43_1978 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH43_1979 ENOG4105CNN ABC, transporter CH43_1982 ENOG4107FKK extracellular solute-binding protein family 1 CH43_1984 ENOG4105EG2 ABC transporter, permease CH43_1988 ENOG4105CI1 PTS System CH43_199 ENOG4105C5R Aminotransferase CH43_1990 ENOG4105ETE Transcriptional regulator (LacI family CH43_1992 ENOG4105DPW Major facilitator superfamily MFS_1 CH43_1993 ENOG4105ETE Transcriptional regulator (LacI family CH43_1996 ENOG4105D2N Aldolase CH43_1998 ENOG4105ENH Sulfatase CH43_1999 ENOG4105C4X radical SAM domain protein CH43_2001 ENOG4105CHR reductase CH43_2002 ENOG4105CE4 GlcNAc 6-P deacetylase CH43_2003 ENOG4108YTN IIa component CH43_2004 ENOG4105F3R pts system mannose fructose sorbose family iid CH43_2005 ENOG4105ETZ PTS System CH43_2006 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB CH43_2007 ENOG4105E70 isomerase CH43_2008 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of CH43_2009 ENOG4105E98 transcriptional regulator DeoR family CH43_2010 ENOG4105CBG Sulfatase CH43_2018 ENOG4107B2H carbonic anhydrase CH43_202 ENOG4105C5R Aminotransferase CH43_2022 ENOG4107QHF type ii secretion system protein e CH43_2024 ENOG4105D7Q type ii secretion system CH43_204 ENOG4105E5Q amino acid AbC transporter CH43_2040 ENOG4105C8Q Methyl-accepting chemotaxis CH43_2042 ENOG4105EJC lysr family transcriptional regulator CH43_2043 ENOG4105RQF LysR family Transcriptional regulator CH43_2044 ENOG4105F27 Major Facilitator CH43_2045 ENOG41060NJ transcriptional regulator CH43_2046 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CH43_2052 ENOG4105CPC Aldo Keto reductase CH43_2055 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase CH43_2063 ENOG4105DSY exodeoxyribonuclease V, gamma CH43_2064 ENOG4107QXK peptidase CH43_2065 ENOG4107QKA exodeoxyribonuclease V beta CH43_2066 ENOG4107QYX exodeoxyribonuclease v alpha CH43_2070 ENOG4107QZM n-acetylglutamate synthase CH43_2071 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CH43_2075 ENOG4105CA3 membrane-bound lytic murein transglycosylase CH43_2076 ENOG4105CUZ uba thif-type nad fad binding protein CH43_2077 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) CH43_2078 ENOG4105C9B Cysteine desulfurase CH43_2080 ENOG4105ETT transcriptional Regulator, LysR family CH43_2081 ENOG4105M08 Membrane CH43_2083 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease CH43_2084 ENOG4105EWT decarboxylase family CH43_2087 ENOG4108RS6 transposase CH43_2088 ENOG4105WP7 tRNA pseudouridine synthase C CH43_2089 ENOG4105DR9 pseudouridine synthase CH43_2090 ENOG4105QDK Flavodoxin CH43_2094 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CH43_21 ENOG4105WQ3 Rna-binding protein CH43_2100 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) CH43_2101 ENOG4105KNE Phosphatidate cytidylyltransferase CH43_2102 ENOG4105DZP Membrane-associated zinc metalloprotease CH43_2104 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) CH43_2108 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) CH43_211 ENOG4105EQ0 Major Facilitator superfamily CH43_2110 ENOG4105C0B DNA polymerase III (alpha subunit) CH43_2112 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CH43_2113 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) CH43_2115 ENOG4105M1T rho-binding antiterminator CH43_2117 ENOG4108VWS Yaeq family CH43_2118 ENOG4108YZN class I peptide chain release factor CH43_2119 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion CH43_212 ENOG4108UMN azlc family CH43_2121 ENOG4108R96 Methyltransferase, YaeB family CH43_2122 ENOG4108R8X outer membrane lipoprotein CH43_2123 ENOG4105D01 (LipO)protein CH43_2124 ENOG4108UMI ABC transporter, permease CH43_2126 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CH43_213 ENOG4105ZED uncharacterized protein ygaH CH43_2132 ENOG4105CV8 reductase CH43_2135 ENOG4105E9H Lytic Murein transglycosylase CH43_2137 ENOG4105D1A Methyltransferase CH43_2139 ENOG4108JDX DNA polymerase iii, epsilon subunit CH43_214 ENOG4105NTK Transcriptional repressor Mpra CH43_2141 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease CH43_2143 ENOG4105GIJ Glycine betaine CH43_2144 ENOG4108HQS Glycine betaine CH43_2145 ENOG4108IJ7 Glycine betaine CH43_2146 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH43_215 ENOG4105CW7 secretion protein, HlyD family CH43_2151 ENOG4108WMJ Protein of unknown function (DUF2002) CH43_2152 ENOG4108SAJ Protein of unknown function (DUF1198) CH43_2154 ENOG4105VEQ Cold shock protein CH43_2155 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein CH43_2156 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH43_2157 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH43_2158 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) CH43_2159 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CH43_216 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH43_2166 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) CH43_217 ENOG4105EIB trna rrna methyltransferase CH43_2170 ENOG4105XXV Acid-resistance protein CH43_2171 ENOG4107SVH Potassium channel protein CH43_2172 ENOG41086WQ Protein CrcB homolog CH43_2173 ENOG41085Q9 Protein CrcB homolog CH43_2174 ENOG4105VZJ PTS System CH43_2175 ENOG4105CK1 PTS System CH43_2176 ENOG4105VCP PTS System CH43_2177 ENOG4105EZV Transcriptional regulator CH43_218 ENOG4105K63 Thioredoxin CH43_2182 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CH43_2186 ENOG4105EEX Two component transcriptional regulator (Winged helix family CH43_219 ENOG4106IUH DTW domain containing protein CH43_2192 ENOG4105XIQ Protein of unknown function (DUF2517) CH43_2193 ENOG4107SEY Conserved Protein CH43_2194 ENOG4105CVP deoxyribo-dipyrimidine photolyase CH43_2195 ENOG4107RF4 Phosphodiesterase CH43_2196 ENOG4107QNR UPF0135 protein CH43_2198 ENOG4105P4J Allophanate hydrolase, subunit 1 CH43_2199 ENOG4107R7A Allophanate hydrolase subunit 2 CH43_22 ENOG4108RS6 transposase CH43_220 ENOG4105CD5 CoA-binding domain protein CH43_221 ENOG4105JIM Phosphatidylserine synthase CH43_2210 ENOG4105C1J atp-dependent rna helicase CH43_2212 ENOG4108IYU L-aspartate oxidase CH43_2214 ENOG41069PW sigma-e factor negative regulatory protein CH43_2215 ENOG4105VQK sigma E regulatory protein, MucB RseB CH43_2216 ENOG4105WMJ Positive regulator of sigma E, RseC MucC CH43_2219 ENOG4105C3F Signal peptidase i CH43_222 ENOG4105T42 (LipO)protein CH43_2223 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) CH43_2225 ENOG4108RS6 transposase CH43_2226 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH43_2229 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH43_2232 ENOG4105DAN ATP-dependent protease CH43_2235 ENOG4105UYK outer membrane protein a CH43_2237 ENOG4108RZ1 DNA transformation protein CH43_2238 ENOG4105EM2 membrane CH43_2239 ENOG410901E Membrane CH43_2240 ENOG41088T4 Helicase IV CH43_2242 ENOG4108Q67 UPF0319 protein CH43_2243 ENOG4105K4P CoA-binding domain protein CH43_2247 ENOG4108Z0T Part of a sulfur-relay system (By similarity) CH43_2249 ENOG4108BUD transposase CH43_2256 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) CH43_2257 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH43_2258 ENOG4105CHR reductase CH43_2259 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase CH43_2261 ENOG4108KQ6 Enoyl-CoA hydratase CH43_2262 ENOG4105CHR reductase CH43_2264 ENOG41062T2 Acyl carrier protein CH43_2265 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CH43_2271 ENOG4105CDV Ompa motb domain protein CH43_2273 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH43_2292 ENOG4105C5H ABC transporter CH43_2294 ENOG4105D06 uba thif-type nad fad binding protein CH43_2295 ENOG4105CVM Molybdenum cofactor synthesis domain protein CH43_2297 ENOG4105C19 ABC transporter CH43_2298 ENOG4105ENT Efflux transporter rnd family, mfp subunit CH43_2303 ENOG4105EGI Transcriptional regulator CH43_2304 ENOG4105CBP Major Facilitator CH43_2306 ENOG4105DHF Membrane CH43_2309 ENOG4108HWV )-transporter CH43_231 ENOG4108Y73 Membrane CH43_2313 ENOG4107SDZ Galactoside transport system permease protein mglC CH43_2314 ENOG4107GZ4 SanA protein CH43_2317 ENOG41067MG lrgb family CH43_2319 ENOG4105E5W Transporter CH43_2323 ENOG4108RS6 transposase CH43_2325 ENOG4105D1F ATP-binding protein CH43_2328 ENOG4108GAE asmA family CH43_2329 ENOG4105EE5 Membrane protein terC CH43_233 ENOG4105C5Q Transcriptional regulator CH43_2330 ENOG4108819 ferric iron reductase CH43_2331 ENOG4105DY8 decarboxylase CH43_2332 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CH43_2334 ENOG4105DUU IucA IucC family protein CH43_2335 ENOG4105E0A ABC, transporter CH43_2336 ENOG4105TVJ transport system, permease CH43_2337 ENOG4105DQ5 transport system permease protein CH43_2338 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CH43_2339 ENOG4105CNM Receptor CH43_2340 ENOG4105DUU IucA IucC family protein CH43_2341 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CH43_2342 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CH43_2343 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CH43_2344 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase CH43_2347 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) CH43_2348 ENOG4105ECC imidazole-glycerol-phosphate dehydratase CH43_235 ENOG4105EHV domain protein CH43_2350 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) CH43_2352 ENOG4108535 NAD dependent epimerase/dehydratase family CH43_2354 ENOG4105CNN ABC, transporter CH43_2356 ENOG4105C2J ABC transporter CH43_2357 ENOG4107SCQ Iron-containing alcohol dehydrogenase CH43_2359 ENOG4105CUB amino acid CH43_236 ENOG4107QN2 dihydrolipoyl dehydrogenase CH43_2360 ENOG4105CJB Exodeoxyribonuclease I CH43_2363 ENOG4105TNG K13735 adhesin invasin CH43_2365 ENOG4105CSP Major Facilitator Superfamily CH43_2366 ENOG4105KIR Thiol-disulfide oxidoreductase dcc CH43_2367 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CH43_2369 ENOG4105DIA mandelate racemase muconate lactonizing CH43_237 ENOG4105YHG TonB family CH43_2373 ENOG4105UQX Mate efflux family protein CH43_2377 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme CH43_2379 ENOG4108KX4 response regulator CH43_238 ENOG4107QZV Type I secretion membrane fusion protein CH43_2380 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CH43_2382 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CH43_2383 ENOG4108TSE Transferase CH43_2387 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) CH43_2393 ENOG4108RS6 transposase CH43_2394 ENOG4105BZ1 (ABC) transporter CH43_2398 ENOG4105N4N Protein of unknown function (DUF2766) CH43_2399 ENOG4105TIK CH43_2400 ENOG41064PC CH43_2403 ENOG4105C85 amino acid CH43_2406 ENOG4105VEQ Cold shock protein CH43_2407 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CH43_2408 ENOG4105DHI Methyltransferase CH43_241 ENOG4105X58 receptor CH43_2410 ENOG4105BZU Histidine kinase CH43_2414 ENOG4105F3R pts system mannose fructose sorbose family iid CH43_2415 ENOG4105ETZ PTS System CH43_2416 ENOG4108EQA pts system CH43_2417 ENOG4105EE5 Membrane protein terC CH43_2418 ENOG4108V8F Transcriptional regulator, MarR family CH43_2421 ENOG4105C26 Dehydrogenase CH43_2422 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase CH43_2427 ENOG4105EFA 4-hydroxyphenylacetate CH43_2428 ENOG4107UWN reductase CH43_2429 ENOG4105EJQ L-serine dehydratase CH43_2431 ENOG4105CRQ synthase (Component I) CH43_2434 ENOG4105C1J atp-dependent rna helicase CH43_2435 ENOG4105X2V dna damage-inducible protein CH43_2438 ENOG4105CUG Oligopeptidase b CH43_2440 ENOG4105MPK DNA polymerase III subunit theta CH43_2441 ENOG41090A1 ferritin CH43_2442 ENOG4105FXM Copper resistance protein CH43_2444 ENOG4105NKT exported protein CH43_2447 ENOG4105D00 flagellar biosynthetic protein flhB CH43_2448 ENOG4105D7B Flagellar biosynthesis protein flha CH43_2449 ENOG4105W13 flagellar protein CH43_245 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase CH43_2453 ENOG4105QVD Flagella synthesis protein FlgN CH43_2454 ENOG4105M9M anti-sigma28 factor FlgM CH43_2455 ENOG4105CKS Flagella basal body P-ring formation protein flgA CH43_2456 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CH43_2457 ENOG4108ZC9 flagellar basal-body rod protein flgc CH43_2458 ENOG4105W00 Flagellar hook capping protein CH43_2459 ENOG4105BZE flagellar hook protein, FlgE CH43_2460 ENOG4108KPB Flagellar basal-body rod protein FlgF CH43_2461 ENOG4105CGA flagellar basal-body rod protein FlgG CH43_2464 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CH43_2465 ENOG4105E1Q flagellar hook-associated protein CH43_2466 ENOG4105DTJ flagellar hook-associated protein CH43_2467 ENOG4105DKT Transcriptional regulator CH43_2469 ENOG4105CNN ABC, transporter CH43_2471 ENOG4105C2J ABC transporter CH43_2472 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CH43_2473 ENOG4108MGF sugar kinase CH43_2476 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CH43_2477 ENOG4105VS8 Flagellar biosynthetic protein fliq CH43_2478 ENOG4105CN7 Flagellar biosynthetic protein FliP CH43_2480 ENOG4105DD5 Flagellar motor switch protein CH43_2481 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CH43_2482 ENOG4107ZI8 flagellar basal body-associated protein flil CH43_2483 ENOG4105WF4 Flagellar hook-length control protein CH43_2484 ENOG4105GSA Flagellar export protein flij CH43_2485 ENOG4108JIR Flagellum-specific ATP synthase CH43_2486 ENOG41090PJ Flagellar assembly protein CH43_2487 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CH43_2488 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CH43_2489 ENOG4105VQ0 flagellar hook-basal body complex protein fliE CH43_249 ENOG4105DQ6 Transposase CH43_2493 ENOG4105DHT Metal Dependent Phosphohydrolase CH43_2496 ENOG4105MQ3 flagellar protein FliS CH43_2497 ENOG4105DTS flagellar hook-associated CH43_2498 ENOG4105I03 Flagellin CH43_2499 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH43_25 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CH43_2500 ENOG4108M9K flagella biosynthesis protein FliZ CH43_2501 ENOG4105K6H D-cysteine desulfhydrase CH43_2504 ENOG4105E5Q amino acid AbC transporter CH43_2505 ENOG4105CDA abc transporter atp-binding protein CH43_2508 ENOG4105C26 Dehydrogenase CH43_2510 ENOG4105CK7 Sodium proline symporter CH43_2513 ENOG4105DBE peroxidase CH43_2516 ENOG4105C85 amino acid CH43_2518 ENOG4108T1M outer membrane protein x CH43_2520 ENOG4105RA2 Membrane CH43_2521 ENOG4105XVG cytoplasmic protein CH43_2522 ENOG4105WH1 Two component transcriptional regulator luxr family CH43_2533 ENOG4108WC9 type VI secretion system effector, hcp1 family CH43_254 ENOG4105CHV Transcription elongation factor NusA CH43_2552 ENOG4105FDP GntR family transcriptional regulator CH43_2553 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) CH43_2556 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component CH43_2557 ENOG4108IJ9 (ABC) transporter CH43_2569 ENOG4107ZSV Receptor CH43_2570 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CH43_2574 ENOG4105C0W non-ribosomal peptide synthetase CH43_2577 ENOG4105BZ1 (ABC) transporter CH43_2578 ENOG4105EYM Major Facilitator superfamily CH43_2584 ENOG4108MQF Chaperone CH43_2586 ENOG4105CW0 outer membrane usher protein CH43_2589 ENOG4105BZU Histidine kinase CH43_2590 ENOG4108Q9V regulatoR CH43_2592 ENOG4105CYC Transferase CH43_2593 ENOG4105DJG MaoC domain protein dehydratase CH43_2598 ENOG4107RGD Major Facilitator superfamily CH43_260 ENOG4105EEI dihydropteroate synthase CH43_2601 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH43_2602 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CH43_2603 ENOG4105C85 amino acid CH43_2604 ENOG4105MVE transcriptional regulator CH43_2605 ENOG4105CSV Glutaminase CH43_261 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CH43_2611 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CH43_2613 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CH43_2617 ENOG4105H1N peptidase, M24 CH43_2618 ENOG4108TUY outer membrane protein PgaA CH43_2619 ENOG4107BJW polysaccharide deacetylase CH43_2620 ENOG4105CND Glycosyl transferase, family 2 CH43_2621 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD CH43_2624 ENOG4105D5M phosphate starvation-inducible protein CH43_2625 ENOG4105EWV Sodium calcium exchanger membrane region CH43_2627 ENOG4105BZU Histidine kinase CH43_2628 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CH43_263 ENOG4105HBR Rna-binding protein CH43_2637 ENOG4105D5G Transposase CH43_264 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) CH43_2644 ENOG4105CZE histidine utilization repressor CH43_2645 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) CH43_2646 ENOG41090B9 response to stress CH43_2648 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CH43_2649 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CH43_265 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase CH43_2650 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CH43_2664 ENOG4108WF3 methyltransferase CH43_2673 ENOG4105GR3 Histidine kinase CH43_2677 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CH43_2678 ENOG4105ENX hydrolase CH43_2687 ENOG4105C3G gtp-binding protein CH43_2689 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria CH43_269 ENOG4105QYV Membrane CH43_2690 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CH43_2695 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CH43_2696 ENOG4108YY7 Invasion gene expression up-regulator SirB CH43_2697 ENOG41063JG Transcriptional regulator CH43_2699 ENOG4105CHH sulfate transporter CH43_27 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CH43_2703 ENOG4105EG2 ABC transporter, permease CH43_2704 ENOG4105F38 ABC transporter, permease CH43_2707 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH43_2708 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CH43_2709 ENOG4105E2R ROK family CH43_2712 ENOG4107XHZ cytoplasmic chaperone TorD family protein CH43_2713 ENOG4105F3T (LipO)protein CH43_2715 ENOG4105D9U N-acetyltransferase CH43_2716 ENOG4105EP9 oxidoreductase CH43_2717 ENOG4105CJR Integral membrane protein (MviN CH43_272 ENOG4105EAH synthase CH43_2721 ENOG4106ZCM YecM protein CH43_2725 ENOG4105WJG Glutathione CH43_2726 ENOG41081XQ Conserved Protein CH43_2728 ENOG4108TIT dATP pyrophosphohydrolase CH43_2733 ENOG4105FAV ABC, transporter CH43_2735 ENOG4105NXV High-affinity zinc uptake system protein CH43_2736 ENOG4105DR5 peptidase CH43_2737 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CH43_2738 ENOG4105CA9 Pyruvate kinase CH43_2739 ENOG4106KNT transcriptional regulator CH43_274 ENOG4105HVQ Regulatory factor of maltose metabolism CH43_2740 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CH43_2742 ENOG4108UHU Aldolase CH43_2745 ENOG4105M4H endoribonuclease L-psp CH43_2746 ENOG4105DVT helicase CH43_2747 ENOG41072GX Peptidase M22 Glycoprotease CH43_2748 ENOG4105Y4Z Outer Membrane Lipoprotein CH43_2749 ENOG4105CEY Amp-dependent synthetase and ligase CH43_2750 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) CH43_2751 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) CH43_2752 ENOG4107QMS site-determining protein CH43_2755 ENOG4105CVE Lytic murein transglycosylase CH43_2756 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CH43_2758 ENOG4107R08 Integrase CH43_2763 ENOG4105NY2 NinB protein CH43_2765 ENOG4105HRS Antitermination protein CH43_278 ENOG4105DFU Cell wall formation (By similarity) CH43_2793 ENOG4108RS6 transposase CH43_28 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CH43_280 ENOG4105F0N pyrophosphate phospho-hydrolase CH43_2809 ENOG4105UZW Tail fiber assembly protein CH43_281 ENOG4108ZHD aig2 family CH43_2811 ENOG4105C3J Cysteine desulfurase CH43_2817 ENOG4105ED1 spovr family CH43_2819 ENOG4105CNH Multidrug resistance protein MdtL CH43_282 ENOG4105MA0 exported protein CH43_2820 ENOG4105EUB pirin domain protein CH43_2821 ENOG4105HEI LysR family (Transcriptional regulator CH43_2824 ENOG4105CYN Serine protein kinase CH43_2825 ENOG4105GNX MltA-interacting MipA family protein CH43_2826 ENOG4105DSB aldose 1-epimerase CH43_2829 ENOG4105VUT cytoplasmic protein CH43_283 ENOG4105CFU surface antigen CH43_2830 ENOG4108RWI nicotinamidase CH43_2831 ENOG4105HDK L-asparaginase CH43_2832 ENOG4105D07 Signal peptide peptidase, SppA CH43_2833 ENOG41069NU Nitroreductase CH43_2834 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) CH43_2835 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CH43_2836 ENOG4105MTM Protein of unknown function (DUF1496) CH43_2837 ENOG4105M6F mutator MutT protein CH43_2838 ENOG4105CGK Exodeoxyribonuclease III CH43_2839 ENOG4105SKE transcriptional Regulator LysR family CH43_2844 ENOG4105CIY formyltetrahydrofolate deformylase CH43_2846 ENOG4105I93 response regulator CH43_2847 ENOG4105C6Y Udp-glucose 6-dehydrogenase CH43_285 ENOG4105C37 (CBS) domain CH43_2850 ENOG4107104 thymidine kinase CH43_2851 ENOG4108EKI Dehydrogenase CH43_2852 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein CH43_2853 ENOG4107QSI ABC, transporter CH43_2855 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH43_2856 ENOG4105C3U ABC transporter CH43_2857 ENOG4108JQ7 (ABC) transporter CH43_286 ENOG41061GZ Protein of unknown function (DUF1107) CH43_2861 ENOG4108T1M outer membrane protein x CH43_2864 ENOG4105K9H YciI-like protein CH43_2866 ENOG410822N TonB family CH43_2868 ENOG4105NAU thioesterase Superfamily protein CH43_287 ENOG4108UUE Transcriptional regulator CH43_2873 ENOG4105EIF outer membrane protein W CH43_2877 ENOG4105DK0 Indole-3-glycerol phosphate synthase CH43_2879 ENOG4105DDQ anthranilate synthase CH43_288 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase CH43_2881 ENOG4105DB7 PHP domain protein CH43_2882 ENOG4107RTD sua5 ycio yrdc ywlc family protein CH43_2883 ENOG4105FE9 pseudouridine synthase CH43_2884 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CH43_2885 ENOG4105UBK short-chain dehydrogenase reductase CH43_2886 ENOG4105ERU peptidase CH43_2887 ENOG4105RKX Protein of unknown function (DUF2498) CH43_2889 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CH43_289 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic CH43_2890 ENOG4108RS6 transposase CH43_2891 ENOG4107R11 Transcriptional regulator CH43_2893 ENOG4107QM5 aconitate hydratase CH43_2894 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) CH43_2895 ENOG4105EYK Phosphatidylglycerophosphatase B CH43_2896 ENOG4105Q4A inner membrane protein yciS CH43_2897 ENOG4105CFV Tetratricopeptide repeat protein CH43_29 ENOG4105CV6 ABC transporter, permease CH43_2900 ENOG4108ZJT translation initiation factor, Sui1 CH43_2902 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CH43_2904 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CH43_2905 ENOG4105VCD cytoplasmic protein CH43_2906 ENOG4105D22 carbon starvation protein CH43_2908 ENOG4105CSP Major Facilitator Superfamily CH43_2909 ENOG4105EXW epimerase dehydratase CH43_291 ENOG4108V1T peptidylprolyl cis-trans isomerase CH43_2910 ENOG4105CSM endonuclease III CH43_2912 ENOG4108UQQ Electron transport complex CH43_2913 ENOG4105D6A Electron transport complex CH43_2914 ENOG4105UEI Transcriptional Regulator AraC Family CH43_2918 ENOG4105M9B inner membrane protein ydgK CH43_2919 ENOG4108JJA ABC, transporter CH43_292 ENOG4105FHY Opacity-associated protein A CH43_2920 ENOG4105BZ1 (ABC) transporter CH43_2922 ENOG4105C42 Type I secretion membrane fusion protein (HlyD CH43_2923 ENOG4108JJA ABC, transporter CH43_2927 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator CH43_2932 ENOG4105D9R oxidoreductase CH43_2933 ENOG4105DHU Bile acid CH43_2935 ENOG4106J39 exported protein CH43_2936 ENOG4105EIP mannose-6-phosphate isomerase CH43_2937 ENOG4105C9Q fumarate hydratase class II CH43_2938 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) CH43_2939 ENOG4105D94 Major Facilitator Superfamily CH43_294 ENOG4108RS6 transposase CH43_2940 ENOG4106NZI LysR family Transcriptional regulator CH43_2941 ENOG4105DAG ROK family CH43_2943 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CH43_2944 ENOG4105CMQ Chloride channel CH43_2945 ENOG4105KBG Protein of unknown function (DUF1161) CH43_2946 ENOG41060NJ transcriptional regulator CH43_2948 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH43_2949 ENOG4107UWC ABC, transporter CH43_2950 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CH43_2952 ENOG4105FYV Amp nucleosidase CH43_2958 ENOG4105C7K acetolactate synthase CH43_2959 ENOG4105M71 acetolactate synthase 1 regulatory subunit CH43_296 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) CH43_2960 ENOG4105PAD Hydrolase CH43_2963 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CH43_2964 ENOG4105DS0 Transcriptional regulator, Crp Fnr family CH43_2965 ENOG4105Q9Y Universal stress protein CH43_2966 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CH43_2967 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CH43_2968 ENOG4105C5D exported protein CH43_2969 ENOG4105D5Q Arginine ornithine antiporter CH43_2971 ENOG4107EXC regulatoR CH43_2972 ENOG4105JJR Histidine kinase CH43_2973 ENOG4105CTD carboxy-peptidase CH43_2978 ENOG4105DS1 cytochrome b561 CH43_2980 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap CH43_2983 ENOG4105CQ7 ATP-dependent helicase CH43_2985 ENOG4105DKT Transcriptional regulator CH43_2986 ENOG4105DEI Mannitol dehydrogenase CH43_2987 ENOG4105WXT Conserved Protein CH43_2988 ENOG410689M (LipO)protein CH43_2989 ENOG4107H52 Dicarboxylate transport CH43_299 ENOG4108MXZ Esterase CH43_2990 ENOG4105C5I Dehydrogenase CH43_2991 ENOG41090X5 Heat shock protein hslJ CH43_2993 ENOG4105KT7 mgtC SapB transporter CH43_2995 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) CH43_30 ENOG4108I0Y (ABC) transporter CH43_3001 ENOG4107QSI ABC, transporter CH43_3002 ENOG4105KXI murein peptide amidase A CH43_3003 ENOG4107S8C mandelate racemase muconate lactonizing CH43_3004 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CH43_3012 ENOG4105CM6 amino acid regulated cytosolic protein CH43_3014 ENOG4105FM1 phage shock protein C CH43_3015 ENOG4105YYT phage shock protein B CH43_3016 ENOG41087YS Phage shock protein A CH43_3017 ENOG4105E51 psp operon transcriptional activator CH43_3018 ENOG4108RS6 transposase CH43_3019 ENOG4108HIY periplasmic CH43_3020 ENOG4108I5W peptide transport system, permease protein CH43_3021 ENOG4108EU3 peptide transport system, permease CH43_3022 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein CH43_3023 ENOG4108JQ2 peptide transport system atp-binding protein CH43_3024 ENOG4105Q4T oxidoreductase CH43_3026 ENOG4105DUX Transporter CH43_3027 ENOG41069YE inner membrane protein yohC CH43_3028 ENOG4108ZR5 Conserved Protein CH43_3029 ENOG4108K3A Glutathione S-transferase CH43_3033 ENOG410642K Lysozyme inhibitor CH43_3035 ENOG4108XTF Outer Membrane Lipoprotein CH43_3037 ENOG4107RGM aldo keto reductase CH43_3038 ENOG4105XZD Fe-S protein CH43_3039 ENOG4105DIJ Phosphoethanolamine transferase CH43_304 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CH43_3040 ENOG4108WUH Transcriptional regulator, TetR family CH43_3041 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CH43_3043 ENOG4108UYE Lactoylglutathione lyase CH43_3045 ENOG4105M2J Glutaredoxin CH43_3047 ENOG4105K4H Nlp p60 protein CH43_3048 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CH43_305 ENOG4105D4A Cell wall formation (By similarity) CH43_3051 ENOG4105F52 Transcriptional regulator CH43_3052 ENOG4105CZQ inner membrane transport protein YdhC CH43_3053 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CH43_3054 ENOG4108R6K riboflavin synthase, subunit alpha CH43_3058 ENOG4105CA9 Pyruvate kinase CH43_3059 ENOG4105KMX major outer membrane lipoprotein CH43_3064 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CH43_3067 ENOG4105JRK feS assembly protein SufD CH43_3068 ENOG4105C3K feS assembly ATPase SufC CH43_3069 ENOG4105DIW FeS assembly protein SUFB CH43_3070 ENOG4108Z4V iron-sulfur cluster assembly CH43_3071 ENOG4105KA0 thioesterase Superfamily protein CH43_3072 ENOG4105CQB FAD linked oxidase domain protein CH43_3073 ENOG4105IPI Membrane CH43_3074 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CH43_3076 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH43_3079 ENOG4108QBX (LipO)protein CH43_3087 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) CH43_3088 ENOG4108V06 Glutathione peroxidase CH43_3091 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CH43_3092 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) CH43_3093 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) CH43_3098 ENOG41087WU CH43_31 ENOG4108UJV acyl-CoA thioesterase i CH43_3102 ENOG4105DSE periplasmic solute binding protein CH43_3103 ENOG4105DIK (ABC) transporter CH43_3104 ENOG4105CC5 ABC transporter CH43_3105 ENOG4105CC5 ABC transporter CH43_3106 ENOG4105FGM Fructosamine kinase CH43_3107 ENOG4107PN8 YfeABCD locus regulator CH43_3108 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 CH43_311 ENOG4108RR8 protoporphyrinogen oxidase CH43_3110 ENOG4105M5J Cupin 2, conserved barrel domain protein CH43_3112 ENOG4105CHR reductase CH43_3113 ENOG41061NF Pectate lyase CH43_3114 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component CH43_3115 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component CH43_3117 ENOG4105WEM extracellular solute-binding protein CH43_3118 ENOG4108PU9 oligogalacturonate-specific porin CH43_3119 ENOG4107K5X Membrane-bound metal-dependent hydrolase CH43_312 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CH43_3120 ENOG4108ETY sodium dicarboxylate symporter CH43_3121 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH43_3123 ENOG4105CAZ oligogalacturonide lyase CH43_3124 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH43_3125 ENOG4108VEV chaperone CH43_3128 ENOG4108VEV chaperone CH43_3129 ENOG4105H8W Fimbrial protein CH43_313 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CH43_3132 ENOG4105CN1 protease CH43_3134 ENOG4108ZGC gaf domain protein CH43_3135 ENOG4105H2K paraquat-inducible protein a CH43_3136 ENOG4105DY2 Paraquat-inducible protein b CH43_3140 ENOG4105GQR Chaperone CH43_3143 ENOG4105WT8 Protein of unknown function (DUF1480) CH43_3153 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CH43_3156 ENOG4105EUR Domain-Containing protein CH43_3157 ENOG4105EUR Domain-Containing protein CH43_3158 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH43_3159 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) CH43_3160 ENOG4108VYJ response regulator receiver protein CH43_3162 ENOG4105BZU Histidine kinase CH43_3163 ENOG4105C8Q Methyl-accepting chemotaxis CH43_3164 ENOG4105C8Q Methyl-accepting chemotaxis CH43_3168 ENOG4105WWK YheO domain protein CH43_317 ENOG4107QK7 reductase CH43_3170 ENOG4105KME endoribonuclease L-psp CH43_3171 ENOG4105R9B Major Facilitator CH43_3172 ENOG4108V3W Chemotaxis protein, CheW CH43_3173 ENOG4105CBS Chea signal transduction histidine kinase CH43_3174 ENOG4105ER2 Ompa motb domain protein CH43_3175 ENOG4107RD7 Flagellar Motor Protein, MotA CH43_3176 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region CH43_3177 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) CH43_3178 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CH43_3179 ENOG4105KT7 mgtC SapB transporter CH43_3180 ENOG4105C8Q Methyl-accepting chemotaxis CH43_3181 ENOG4105C8Q Methyl-accepting chemotaxis CH43_3183 ENOG4105VEQ Cold shock protein CH43_3186 ENOG4105GSJ Inner membrane protein ylaC CH43_3187 ENOG4108XM1 transcriptional regulator AsnC family CH43_3189 ENOG41061EV selenium-binding protein YdfZ CH43_319 ENOG4105MDZ Transcriptional activator rfaH CH43_3190 ENOG4105D6F Phosphatase CH43_3192 ENOG4105KVH Transcriptional regulator CH43_3193 ENOG4105ECR NmrA family CH43_3194 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor CH43_3196 ENOG4106NDP Transcriptional regulator CH43_3197 ENOG4108HMX isocitrate dehydrogenase (NADP) CH43_3198 ENOG4108R99 pseudouridine synthase CH43_32 ENOG4105E1F short-chain dehydrogenase reductase CH43_320 ENOG4105D52 delta-aminolevulinic acid dehydratase CH43_3202 ENOG4107QTF adenylosuccinate lyase CH43_3204 ENOG4105XJC Two component transcriptional regulator (Winged helix family CH43_3206 ENOG4105EZE Cupin 4 family protein CH43_3208 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CH43_3210 ENOG4105D60 lipoprotein releasing system transmembrane protein CH43_3212 ENOG4105D60 lipoprotein releasing system transmembrane protein CH43_3213 ENOG4108JA2 transcriptioN-repair coupling factor CH43_3214 ENOG4107MBR 17 kDa surface antigen CH43_3218 ENOG4105CEP NADH dehydrogenase CH43_322 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CH43_3220 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) CH43_3223 ENOG41090DQ Lipoprotein CH43_3224 ENOG4105K59 histidine triad (HIT) protein CH43_3225 ENOG4105F9E Shikimate 5-dehydrogenase CH43_3227 ENOG4105CI1 PTS System CH43_3228 ENOG4105F8V Hydrolase, tatD family CH43_3229 ENOG4107QRG dna polymerase iii CH43_3231 ENOG4105HHA aminodeoxychorismate lyase CH43_3232 ENOG4105YAZ 4-amino-4-deoxychorismate lyase CH43_3233 ENOG4108RS6 transposase CH43_3234 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH43_3236 ENOG4105CHR reductase CH43_3237 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CH43_324 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) CH43_3240 ENOG4105VGS 50s ribosomal protein l32 CH43_3241 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein CH43_3243 ENOG4105EI2 Pseudouridine synthase CH43_3244 ENOG4107QQB Ribonuclease E CH43_3245 ENOG41067V3 Antibiotic biosynthesis monooxygenase CH43_3249 ENOG4105PVA Biofilm formation regulatory protein BssS CH43_3252 ENOG4105DSF transport protein CH43_3256 ENOG4105VJY transcriptional regulator CH43_3257 ENOG4107YC3 synthase CH43_3258 ENOG4105ETT transcriptional Regulator, LysR family CH43_326 ENOG4105JC1 sterol-binding domain protein CH43_3260 ENOG4105C54 Major Facilitator superfamily CH43_3262 ENOG4105CPC Aldo Keto reductase CH43_3263 ENOG4108Y1S CRISPR-associated protein, Csy4 family CH43_3264 ENOG4105M6W Crispr-associated protein, Csy3 family CH43_3265 ENOG4105DZX CRISPR-associated protein, Csy2 family CH43_3266 ENOG4105ENG CRISPR-associated protein, Csy1 family CH43_3267 ENOG4107IIZ CRISPR-associated helicase, Cas3 CH43_3268 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CH43_3269 ENOG4105CUY Mechanosensitive ion channel CH43_3273 ENOG4105HY2 Glycosidase related protein CH43_3274 ENOG4105DRS transport system, permease CH43_3277 ENOG4105ETE Transcriptional regulator (LacI family CH43_3279 ENOG4108IJ9 (ABC) transporter CH43_328 ENOG4105CGY Dna recombination protein CH43_3282 ENOG4105CKT filamentous hemagglutinin CH43_3286 ENOG4105CKT filamentous hemagglutinin CH43_3289 ENOG4105CKT filamentous hemagglutinin CH43_329 ENOG4108KF1 Membrane CH43_3290 ENOG4105D5K Hemolysin activator protein CH43_3291 ENOG4105E3J oxidoreductase CH43_3292 ENOG4105DVW rieske (2Fe-2S) CH43_3293 ENOG4105C94 Transporter CH43_3294 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CH43_3295 ENOG4105EJC lysr family transcriptional regulator CH43_3296 ENOG4105FKQ transcriptional regulator CH43_3297 ENOG4105CNN ABC, transporter CH43_33 ENOG4107QR8 Thioredoxin CH43_3300 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH43_3301 ENOG4105CPQ Dehydrogenase CH43_3305 ENOG4108T1M outer membrane protein x CH43_3311 ENOG4107R0W ABC transporter CH43_3312 ENOG4105E5Q amino acid AbC transporter CH43_3313 ENOG4105CDA abc transporter atp-binding protein CH43_3314 ENOG4107SDU Methyl-accepting chemotaxis CH43_3316 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction CH43_3317 ENOG4108MTB glycosyl transferase family CH43_3318 ENOG4105CEY Amp-dependent synthetase and ligase CH43_332 ENOG4108I5U Uridine phosphorylase CH43_3320 ENOG4108IPT Naphthoate synthase CH43_3323 ENOG4105E4F Isochorismate synthase CH43_3325 ENOG4105TNS Conserved Protein CH43_3327 ENOG4105C01 Dihydroxy-acid dehydratase CH43_333 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) CH43_3330 ENOG4105C5I Dehydrogenase CH43_3331 ENOG4105K2J Transcriptional regulator CH43_3332 ENOG4105F32 YngK protein CH43_3333 ENOG4105CHR reductase CH43_3334 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CH43_3335 ENOG4108R66 Conserved Protein CH43_3338 ENOG4105C8S subunit m CH43_3339 ENOG4105D65 subunit l CH43_3341 ENOG4107UFS subunit j CH43_3344 ENOG4108IEH NADH dehydrogenase subunit g CH43_3345 ENOG4107QIZ NADH dehydrogenase CH43_3346 ENOG4105GKE subunit e CH43_3348 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CH43_335 ENOG4105EMK carboxylate amino acid amine transporter CH43_3350 ENOG4107NQ8 LysR family Transcriptional regulator CH43_3351 ENOG4105CHM Aminotransferase CH43_3353 ENOG4107QWE )-transporter CH43_3354 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 CH43_3358 ENOG4105C6K Malic enzyme CH43_3359 ENOG4107P2S Transcriptional regulator CH43_336 ENOG4105DZ2 Transcriptional regulator CH43_3362 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CH43_3363 ENOG4105PTV Nudix Hydrolase CH43_3367 ENOG4105ECP epimerase CH43_3368 ENOG4108JEH abc transporter atp-binding protein CH43_3369 ENOG4106YG3 ABC transporter CH43_337 ENOG4105RK9 auxin efflux carrier CH43_3370 ENOG4105DSP amino acid AbC transporter CH43_3371 ENOG4105E89 ABC transporter CH43_3372 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CH43_3373 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase CH43_3374 ENOG4105E96 Colicin v production protein CH43_3375 ENOG4108S3P Sporulation domain protein CH43_3376 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CH43_3378 ENOG4105DQR SNARE associated Golgi CH43_338 ENOG4107T6V glycerophosphoryl diester phosphodiesterase CH43_3380 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CH43_3383 ENOG410631K Membrane CH43_3384 ENOG4106WZ1 flagella biosynthesis regulator CH43_3387 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH43_3389 ENOG4105MH2 YfcL protein CH43_3390 ENOG4108BPE -transporting atpase CH43_3391 ENOG4105EJ9 Membrane CH43_3394 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) CH43_3396 ENOG4108BY2 phosphohistidine phosphatase CH43_3399 ENOG4105KZW UPF0381 protein CH43_34 ENOG4107QX8 SPFH domain, Band 7 family protein CH43_3400 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation CH43_3401 ENOG410903C (LipO)protein CH43_3402 ENOG4105KWW Biogenesis protein CH43_3403 ENOG4105KWW Biogenesis protein CH43_3404 ENOG4107QX9 Thiol disulfide interChange protein CH43_3405 ENOG4105DA4 cytochrome c-type biogenesis protein CH43_3407 ENOG4105X3C heme exporter protein CH43_3408 ENOG41060IM Heme exporter protein CH43_3409 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CH43_3413 ENOG4108V0P LemA family CH43_3415 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CH43_3421 ENOG4105CS6 Rhs element vgr protein CH43_3434 ENOG4105CW0 outer membrane usher protein CH43_3436 ENOG4105CW0 outer membrane usher protein CH43_3437 ENOG4105GQR Chaperone CH43_3439 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH43_3449 ENOG4105CVE Lytic murein transglycosylase CH43_3454 ENOG4108WC9 type VI secretion system effector, hcp1 family CH43_3456 ENOG4107QY8 reductase CH43_3457 ENOG4105QAX Iron-sulfur CH43_3458 ENOG4107KGK dmso reductase anchor subunit CH43_3459 ENOG4108NEM leader-binding protein dmsD CH43_3461 ENOG4107Y60 (LipO)protein CH43_3463 ENOG4106B0W Curli production assembly transport component CsgG CH43_3465 ENOG4108VKM cytochrome b561 CH43_3466 ENOG4105CHM Aminotransferase CH43_3467 ENOG41072TH Protein of unknown function (DUF1479) CH43_3470 ENOG4105C5Q Transcriptional regulator CH43_3471 ENOG4105CPC Aldo Keto reductase CH43_3474 ENOG4105D9N nucleoside CH43_3481 ENOG4108RS6 transposase CH43_3484 ENOG4105VRT cytoplasmic protein CH43_3487 ENOG4105EXN Sulfate transport protein CysZ CH43_3488 ENOG4105C6T cysteine synthase CH43_3489 ENOG4105KZ7 phosphocarrier protein hpr CH43_3491 ENOG4105C5Y PTS System CH43_3493 ENOG4108RS6 transposase CH43_3495 ENOG4105E0F Histidine kinase CH43_3496 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH43_3497 ENOG4105DJY efflux transporter, rnd family, mfp subunit CH43_35 ENOG4105G5H Membrane CH43_350 ENOG4108IV0 ABC, transporter CH43_3500 ENOG4105E1V na solute symporter CH43_3502 ENOG4107RAQ aminopeptidase CH43_3504 ENOG4105C87 Aminotransferase class I and II CH43_3506 ENOG41062D9 Histidine kinase CH43_3507 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH43_3509 ENOG4105C6T cysteine synthase CH43_351 ENOG4105C0Z ABC transporter CH43_3510 ENOG4108IJ6 ABC transporter CH43_3511 ENOG4105ECW sulfate abc transporter CH43_3512 ENOG4108I5D sulfate abc transporter CH43_3513 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein CH43_3515 ENOG4105QEK Transcriptional regulator CH43_3516 ENOG4108R66 Conserved Protein CH43_352 ENOG4105CF8 branched-chain amino acid ABC transporter, permease CH43_3521 ENOG4105EZR dyp-type peroxidase family protein CH43_3524 ENOG4105H4F exported protein CH43_353 ENOG4105C32 Amino acid ABC transporter (Permease) CH43_3531 ENOG4105C6K Malic enzyme CH43_3533 ENOG4105CUW cytochrome C-TYPE protein CH43_3534 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) CH43_3536 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase CH43_3537 ENOG4108ZNS ferredoxin-type protein NapF CH43_3538 ENOG4105WH1 Two component transcriptional regulator luxr family CH43_354 ENOG4105CP9 extracellular ligand-binding receptor CH43_3540 ENOG4105BZS acriflavin resistance protein CH43_3542 ENOG4105S2T inner membrane protein YbcI CH43_3543 ENOG4105C4X radical SAM domain protein CH43_3544 ENOG4105ENH Sulfatase CH43_3545 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH43_3546 ENOG4107Z33 ABC transporter, permease CH43_3547 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC CH43_3549 ENOG4105KUZ arsenate reductase CH43_355 ENOG4105U59 -acetyltransferase CH43_3555 ENOG4105CGZ zinc metallopeptidase CH43_3557 ENOG4108RS6 transposase CH43_3558 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH43_356 ENOG4108RS6 transposase CH43_3560 ENOG4105RH4 Glycine cleavage system transcriptional repressor CH43_3561 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CH43_3564 ENOG4105C02 permease CH43_3565 ENOG4105ERG peptidase m48, ste24p CH43_3566 ENOG4105K89 arsenate reductase CH43_3568 ENOG4108RS6 transposase CH43_3571 ENOG4108V3E phosphoribosylglycinamide formyltransferase CH43_3572 ENOG4108MK9 spermidine N(1)-acetyltransferase CH43_3573 ENOG4108C80 FliB family CH43_3574 ENOG4108C80 FliB family CH43_3576 ENOG4105E2Z phosphate ABC transporter (Permease CH43_3577 ENOG4105C8U phosphate abc transporter CH43_3578 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CH43_3579 ENOG4105C9X ppx gppa phosphatase CH43_358 ENOG4105CRP Part of the ABC transporter FtsEX involved in CH43_3580 ENOG4105CJW magnesium transporter CH43_3581 ENOG4105R8A Heat shock protein CH43_3582 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component CH43_3583 ENOG4105F38 ABC transporter, permease CH43_3585 ENOG4108JPW Aminotransferase CH43_3587 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH43_359 ENOG4105CAK Cell division ATP-binding protein ftsE CH43_3593 ENOG4105EB3 Histidine kinase CH43_3594 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH43_3595 ENOG4105KWI UPF0339 protein CH43_3596 ENOG4105CFP Peptidase U32 CH43_3598 ENOG4108ZGU inhibitor of vertebrate lysozyme CH43_36 ENOG4108Z6Z Transcriptional regulator CH43_360 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CH43_360 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CH43_3600 ENOG4105DWF phosphomethylpyrimidine kinase CH43_3609 ENOG4108WC9 type VI secretion system effector, hcp1 family CH43_361 ENOG4106H78 methyltransferase CH43_3610 ENOG4108RS6 transposase CH43_3612 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CH43_3614 ENOG4105VPD cellular component movement CH43_3617 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH43_3618 ENOG4105N21 Membrane CH43_362 ENOG4105MG3 Membrane CH43_3626 ENOG4108MGN ATP-binding component of a transport system CH43_3627 ENOG4108MGN ATP-binding component of a transport system CH43_3629 ENOG4105YYA enhanced serine sensitivity protein SseB CH43_3631 ENOG4105WVQ Fe-S assembly protein IscX CH43_3632 ENOG4108ZIT Ferredoxin, 2FE-2S CH43_3633 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB CH43_3636 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins CH43_3637 ENOG4105C3J Cysteine desulfurase CH43_3641 ENOG4105D7X high-affinity nickel-transporter CH43_3642 ENOG41065CD Exported protein CH43_3643 ENOG4105D8G Major Facilitator superfamily CH43_3644 ENOG4108MN2 Stationary phase inducible protein CsiE CH43_3647 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CH43_365 ENOG4107FS9 Membrane CH43_3650 ENOG4108M21 CH43_3651 ENOG4108YZA Nitrogen regulatory protein pii CH43_3652 ENOG4105C4K Nad synthetase CH43_3653 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH43_3654 ENOG4108SKK alpha helix protein CH43_3655 ENOG4107WP9 Histidine kinase CH43_3662 ENOG4108Z6B deaminase CH43_3663 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB CH43_3665 ENOG4106G6Q Transcriptional regulator CH43_3666 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding CH43_3667 ENOG4108RS6 transposase CH43_3668 ENOG4108Q2G (LipO)protein CH43_3669 ENOG4105DY2 Paraquat-inducible protein b CH43_3670 ENOG4105F1S paraquat-inducible protein a CH43_3671 ENOG4105C5H ABC transporter CH43_3673 ENOG4105QVC MOSC domain-containing protein CH43_3674 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) CH43_3676 ENOG4105CD8 aminopeptidase N CH43_368 ENOG4105EX9 Membrane CH43_3680 ENOG4105CGF Aromatic amino acid aminotransferase CH43_3681 ENOG4105C5X domain protein CH43_3682 ENOG4105EAQ (twin-arginine translocation) pathway signal CH43_3683 ENOG4105DIT ErfK YbiS YcfS YnhG family protein CH43_3686 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) CH43_3687 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) CH43_3688 ENOG4106371 Methyltransferase CH43_3689 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups CH43_369 ENOG4108W1V Lipoprotein CH43_3691 ENOG4105W49 UPF0434 protein CH43_3692 ENOG4105VEQ Cold shock protein CH43_3693 ENOG4105E32 cytoplasmic protein CH43_3696 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 CH43_3699 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CH43_37 ENOG4105C59 p-type ATPase CH43_370 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CH43_3704 ENOG4105EUR Domain-Containing protein CH43_3704 ENOG4105EUR Domain-Containing protein CH43_3705 ENOG4105HDK L-asparaginase CH43_3706 ENOG4105DDY UPF0142 protein ycaO CH43_3707 ENOG4105TMB Formate nitrite transporter CH43_3708 ENOG4105C6N Formate acetyltransferase CH43_3710 ENOG4105F1A Pyruvate formate-lyase CH43_3711 ENOG4108ISG Major Facilitator CH43_3713 ENOG4105D1H recombination factor protein RarA CH43_3716 ENOG4105CNU cell division protein FtsK CH43_3717 ENOG4105EW9 transcriptional regulator AsnC family CH43_3718 ENOG4105C3M thioredoxin reductase CH43_3719 ENOG4108JJ9 ABC, transporter CH43_372 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A CH43_3720 ENOG4108JJ8 (ABC) transporter CH43_3722 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) CH43_3724 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH43_3726 ENOG4105VEQ Cold shock protein CH43_3728 ENOG4105DJY efflux transporter, rnd family, mfp subunit CH43_3729 ENOG4108MJ5 VirK protein CH43_373 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase CH43_3730 ENOG4105CPB ATP-dependent endonuclease of the OLD family CH43_3731 ENOG4105DWU Membrane CH43_3733 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CH43_3734 ENOG4105C7K acetolactate synthase CH43_3735 ENOG4105C5W Aldolase CH43_3736 ENOG4105CGD Nad-dependent epimerase dehydratase CH43_3737 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CH43_3738 ENOG41064MM (LipO)protein CH43_3739 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) CH43_3740 ENOG4105E5Z arginine transporter ATP-binding subunit CH43_3741 ENOG4106PMH Extracellular solute-binding protein family 3 CH43_3742 ENOG4105GBT ABC transporter CH43_3743 ENOG4105DMR ABC, transporter CH43_3744 ENOG4108I0N Transporter, RarD family, DMT superfamily protein CH43_3745 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) CH43_3746 ENOG410642S Nicotianamine synthase protein CH43_3747 ENOG4105E0A ABC, transporter CH43_3748 ENOG4105DQ5 transport system permease protein CH43_375 ENOG4105DQF Hydrolase CH43_3754 ENOG4105RBQ inner membrane protein ybjO CH43_3755 ENOG4105D38 putrescine abc transporter CH43_3756 ENOG4105F38 ABC transporter, permease CH43_3757 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH43_3758 ENOG4107RUE extracellular solute-binding protein family 1 CH43_3759 ENOG4108RMJ sensory transduction regulator CH43_376 ENOG4108EUD Lysophospholipase CH43_3760 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress CH43_3761 ENOG41090BQ Glutaredoxin CH43_3762 ENOG4105D0C transport protein CH43_3764 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CH43_3765 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH43_3766 ENOG4107FB0 transcriptional regulator DeoR family CH43_3767 ENOG4105C44 Serine transporter CH43_3768 ENOG4105DZ1 carboxypeptidase CH43_3769 ENOG4108UMI ABC transporter, permease CH43_3771 ENOG4105D01 (LipO)protein CH43_3774 ENOG4108TGY Glutathione S-transferase CH43_3775 ENOG4105D05 Receptor CH43_3777 ENOG4105EHG Permease protein CH43_378 ENOG4105CCF Lysine exporter protein (Lyse ygga) CH43_3780 ENOG4108IQI permease CH43_3782 ENOG4105DUM transcriptional regulator, lysR family CH43_3783 ENOG4105HMI Membrane CH43_3785 ENOG4108D1K outer membrane usher protein CH43_3786 ENOG4108UIF Chaperone CH43_3789 ENOG4108SGD regulatory protein CH43_379 ENOG4105C9U ATP-dependent DNA helicase RecQ CH43_3790 ENOG4105DM4 PTS System CH43_3791 ENOG4105DE4 1-phosphofructokinase CH43_3792 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein CH43_3794 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CH43_3795 ENOG4105C2J ABC transporter CH43_3797 ENOG4105E66 phosphoriboisomerase A CH43_3799 ENOG4105C26 Dehydrogenase CH43_38 ENOG4105MBR gumn family CH43_380 ENOG4105HDD phospholipase CH43_3802 ENOG4105CHR reductase CH43_3803 ENOG4105KRS Proteinase inhibitor CH43_3806 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) CH43_3807 ENOG4105DEI Mannitol dehydrogenase CH43_3808 ENOG4107YCY Transcriptional regulator CH43_381 ENOG4108VUY thioesterase Superfamily protein CH43_3810 ENOG4105CKI cobalamin synthesis protein CH43_3811 ENOG41076MN Phosphoesterase, PA-phosphatase related CH43_3812 ENOG4107TT5 NLP P60 protein CH43_3814 ENOG4105CXC rtn protein CH43_3815 ENOG4105E43 Extracellular solute-binding protein, family 5 CH43_3816 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component CH43_3817 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component CH43_3818 ENOG4108JQ5 ABC transporter CH43_3819 ENOG4105HG6 CH43_382 ENOG4105FR1 rard protein CH43_3820 ENOG4105C2C drug resistance transporter, Bcr CflA CH43_3821 ENOG4105I08 Pseudouridine synthase CH43_3822 ENOG4105CFI type iii restriction protein res subunit CH43_3824 ENOG4108RS6 transposase CH43_3826 ENOG4105PAN UPF0352 protein CH43_3827 ENOG4105E68 Sulfatase CH43_383 ENOG4107QUT magnesium and cobalt transport protein CorA CH43_3830 ENOG4105GMB type VI secretion system effector, hcp1 family CH43_3834 ENOG4105CS2 ec 3.2.1.21 CH43_3836 ENOG4108Q3X Transcriptional regulator CH43_3840 ENOG4108T86 baseplate J family protein CH43_3849 ENOG4105TKZ Tail Sheath CH43_385 ENOG4105EQN UPF0261 protein CH43_3853 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CH43_3854 ENOG4105MVE transcriptional regulator CH43_3856 ENOG4105G63 Type III effector Hrp-dependent CH43_3857 ENOG4105HRS Antitermination protein CH43_3859 ENOG4105Y50 Virulence Protein CH43_3862 ENOG4105C8Q Methyl-accepting chemotaxis CH43_3864 ENOG4105CT4 transporter CH43_3865 ENOG4107R6D beta-lactam binding protein AmpH CH43_3868 ENOG4105FCK Membrane CH43_387 ENOG4105C4R Atp-dependent dna helicase CH43_3872 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CH43_3873 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CH43_3874 ENOG41068CG regulatoR CH43_3875 ENOG4105BZU Histidine kinase CH43_3876 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH43_3878 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH43_3879 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH43_388 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant CH43_3880 ENOG4105XPH Ferredoxin CH43_3883 ENOG4105E0U tyrosine-specific transport protein CH43_3884 ENOG4108UII YfaZ family CH43_3885 ENOG4105CH6 catalase CH43_3886 ENOG4105DVT helicase CH43_3888 ENOG4105FDR Membrane CH43_389 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CH43_3890 ENOG4105CXN decarboxylase CH43_3892 ENOG4105CXN decarboxylase CH43_3893 ENOG4105D5Q Arginine ornithine antiporter CH43_3894 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component CH43_3895 ENOG4108IJ8 ABC transporter CH43_3896 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component CH43_3897 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system CH43_3898 ENOG4105KHC sulfurtransferase CH43_39 ENOG4108Z66 YbaK ebsC protein CH43_390 ENOG4105CT0 Protein of unknown function, DUF484 CH43_3901 ENOG4108IV0 ABC, transporter CH43_3902 ENOG4108JJB ABC transporter CH43_3903 ENOG4105CNN ABC, transporter CH43_3904 ENOG4105C32 Amino acid ABC transporter (Permease) CH43_3906 ENOG4108W15 Protein of unknown function (DUF1456) CH43_3909 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein CH43_3911 ENOG4105Y3U Transglycosylase-associated protein CH43_3913 ENOG4105N1F Hnh endonuclease CH43_3915 ENOG4105CXG d-lactate dehydrogenase CH43_3916 ENOG41061WM D-Alanyl-D-Alanine CH43_3918 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) CH43_392 ENOG4105S7Z (LipO)protein CH43_3921 ENOG4105EAA nucleoside CH43_3922 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) CH43_3924 ENOG4105CN8 Transcriptional regulator CH43_3925 ENOG4105C94 Transporter CH43_3929 ENOG4108RS6 transposase CH43_3930 ENOG4105HFZ Membrane CH43_3931 ENOG4108ZAF Molybdopterin CH43_3932 ENOG4105M00 molybdopterin converting factor, subunit 1 CH43_3934 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CH43_3936 ENOG4105CHW UPF0052 protein CH43_3937 ENOG4105VYA Uncharacterized conserved protein (DUF2132) CH43_3938 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) CH43_3939 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CH43_394 ENOG4107T0K Adenylate cyclase CH43_3940 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CH43_3941 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CH43_3946 ENOG4108K4B hydrolase CH43_3948 ENOG4105E0C molybdate abc transporter CH43_3949 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CH43_3950 ENOG410680R Protein of unknown function (DUF2592) CH43_3951 ENOG4105F4R Transcriptional regulator mode CH43_3952 ENOG4105DKW ABC transporter CH43_3956 ENOG4105CMR udp-glucose 4-epimerase CH43_3957 ENOG4105F0Z galactose-1-phosphate uridylyltransferase CH43_396 ENOG41076E6 Uroporphyrinogen-III Synthase CH43_3960 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) CH43_3965 ENOG4105PGM cation diffusion facilitator family transporter CH43_3966 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CH43_397 ENOG4105ECF c-methyltransferase CH43_3972 ENOG4105UFD tol-pal system protein YbgF CH43_3973 ENOG4105KCK Peptidoglycan-associated lipoprotein CH43_3975 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CH43_3975 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CH43_3976 ENOG4105M8F Biopolymer transport protein exbD tolR CH43_3977 ENOG4105E02 MotA TolQ exbB proton channel CH43_3978 ENOG4107YD3 Thioesterase CH43_3979 ENOG4105KJB cyd operon protein YbgE CH43_398 ENOG410601J HemY protein CH43_3981 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CH43_3982 ENOG4105C4M (Ubiquinol oxidase) subunit I CH43_3983 ENOG4108RS6 transposase CH43_3984 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CH43_3986 ENOG4105C7S Dehydrogenase CH43_3987 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CH43_3988 ENOG4105E33 succinate dehydrogenase CH43_3990 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein CH43_3991 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit CH43_3992 ENOG4105BZN citrate synthase CH43_3994 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) CH43_3995 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CH43_3996 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH43_3998 ENOG4108Z1B Cyclase dehydrase CH43_4 ENOG4107SET aldo keto reductase CH43_4001 ENOG4105DFP Integrase CH43_4011 ENOG4105VUH addiction module killer protein CH43_4015 ENOG4105DFP Integrase CH43_4018 ENOG4105EV9 Alpha Beta Hydrolase CH43_4020 ENOG4105NNH LexA regulated protein CH43_4021 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) CH43_4022 ENOG41090R7 Ferric uptake CH43_4027 ENOG4105CI1 PTS System CH43_4029 ENOG4105CE4 GlcNAc 6-P deacetylase CH43_4030 ENOG4105E2R ROK family CH43_4031 ENOG4105D4U had-superfamily hydrolase, subfamily iia CH43_4032 ENOG4105CAQ asparagine synthetase CH43_4039 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CH43_4041 ENOG4105C9A Phoh family CH43_4043 ENOG4108JU5 Magnesium and cobalt efflux protein CH43_4044 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) CH43_4045 ENOG4107RP9 extracellular solute-binding protein, family 3 CH43_4046 ENOG4105EAD ABC transporter CH43_4047 ENOG4105DRP amino acid AbC transporter CH43_4048 ENOG4105CDA abc transporter atp-binding protein CH43_4049 ENOG4107PAI alpha helical protein CH43_405 ENOG4105C85 amino acid CH43_4052 ENOG4105DJF DNA polymerase III, delta' subunit CH43_4054 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) CH43_4056 ENOG4105CJN penicillin-binding protein CH43_4057 ENOG4105CNI cell division protein FtsW CH43_4058 ENOG4105K6T rare lipoprotein A CH43_4059 ENOG4105DZ1 carboxypeptidase CH43_4063 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) CH43_4064 ENOG4107Z6W Protein CrcB homolog CH43_4065 ENOG4105VEQ Cold shock protein CH43_4067 ENOG4108N8T regulatoR CH43_4072 ENOG4108JJ7 ABC transporter CH43_4074 ENOG4105DH8 myo-inositol catabolism CH43_4076 ENOG4105EDK PfkB domain protein CH43_4077 ENOG4105CK5 oxidoreductase CH43_4078 ENOG4105CNN ABC, transporter CH43_4079 ENOG4105C2J ABC transporter CH43_4080 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH43_4081 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) CH43_4083 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) CH43_4084 ENOG4105C26 Dehydrogenase CH43_4089 ENOG4105DN3 alpha-2-macroglobulin domain protein CH43_409 ENOG4105EGZ biosynthesis protein CH43_4090 ENOG4108JQB penicillin-binding protein 1C CH43_4091 ENOG4105HVQ Regulatory factor of maltose metabolism CH43_4096 ENOG4108WC9 type VI secretion system effector, hcp1 family CH43_410 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CH43_4101 ENOG4105EZE Cupin 4 family protein CH43_411 ENOG4108WJ1 acetyltransferase CH43_4111 ENOG4106RMF ParB family CH43_4116 ENOG41073YN Protein of unknown function (DUF1380) CH43_412 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CH43_4120 ENOG4105FEQ ParB domain protein nuclease CH43_4123 ENOG4105UZW Tail fiber assembly protein CH43_4124 ENOG4108X9F tail fiber protein CH43_4124 ENOG4108X9F tail fiber protein CH43_413 ENOG4105C1B dTDP-glucose 4-6-dehydratase CH43_4131 ENOG4108NYK Tape measure protein CH43_414 ENOG4108IJ1 Dehydrogenase CH43_415 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CH43_4150 ENOG4105FA0 parb-like partition protein CH43_4151 ENOG4105FA0 parb-like partition protein CH43_4152 ENOG4105CB5 ATP-dependent DNA helicase recG CH43_416 ENOG4105SFE lipopolysaccharide biosynthesis protein CH43_4163 ENOG4108RS6 transposase CH43_4165 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH43_4166 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH43_417 ENOG4105ESV Glycosyl transferase, family 4 CH43_4172 ENOG4105D2X ABC transporter substrate-binding protein CH43_4174 ENOG4106JVB Replication Protein CH43_4182 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) CH43_4184 ENOG4105C2M dna polymerase I CH43_419 ENOG4105K63 Thioredoxin CH43_4190 ENOG4106J5W DNA polymerase III (alpha subunit) CH43_4197 ENOG4108D1K outer membrane usher protein CH43_4198 ENOG4108UIF Chaperone CH43_4199 ENOG4106PHM regulatory protein CH43_42 ENOG4105CGH 5'-nucleotidase CH43_4209 ENOG4105D5G Transposase CH43_422 ENOG4105C4R Atp-dependent dna helicase CH43_423 ENOG4105KQ5 peptidylprolyl cis-trans isomerase CH43_4237 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) CH43_4239 ENOG4106CQM replication CH43_4241 ENOG4105EQR Transposase IS116 IS110 IS902 CH43_426 ENOG4105GQR Chaperone CH43_427 ENOG4105CW0 outer membrane usher protein CH43_429 ENOG4108VEV chaperone CH43_4290 ENOG4105CMM transposase CH43_4292 ENOG4105CMM transposase CH43_43 ENOG4105CGH 5'-nucleotidase CH43_4300 ENOG4106CQM replication CH43_4301 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) CH43_4310 ENOG4105D13 transposase CH43_4312 ENOG4108C33 Resolvase CH43_4316 ENOG4105CMM transposase CH43_4320 ENOG4105CMM transposase CH43_4326 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB CH43_4327 ENOG4105EZN Cobyrinic acid ac-diamide synthase CH43_436 ENOG4105EMY transcriptional regulator CH43_44 ENOG4105CGH 5'-nucleotidase CH43_441 ENOG4105C7B Threonine dehydratase CH43_443 ENOG4105CM2 brancheD-chain amino acid aminotransferase CH43_444 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit CH43_446 ENOG4105C0P Mg chelatase subunit ChlI CH43_447 ENOG4108WFC UPF0438 protein yifE CH43_448 ENOG41062B0 ABC transporter, permease CH43_450 ENOG4107R9N ABC transporter CH43_451 ENOG4105C2J ABC transporter CH43_452 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator CH43_462 ENOG4105C12 Phosphoribosylglycinamide synthetase CH43_463 ENOG4108T8B Protein of unknown function (DUF1481) CH43_465 ENOG4105R2J Conserved Protein CH43_466 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) CH43_47 ENOG4105CKD glutathione-regulated potassium-efflux system protein CH43_471 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) CH43_473 ENOG4105D06 uba thif-type nad fad binding protein CH43_48 ENOG4107RE1 Inosine-guanosine kinase CH43_486 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CH43_487 ENOG4105PM1 preprotein translocase subunit SecE CH43_49 ENOG4108QY5 Ferric enterobactin transport protein CH43_497 ENOG4105C85 amino acid CH43_498 ENOG4105C84 Histidine ammonia-lyase CH43_5 ENOG4105EQ2 LysR family Transcriptional regulator CH43_500 ENOG4105C6T cysteine synthase CH43_506 ENOG4105CM4 permease protein CH43_508 ENOG4108IPW abc transporter atp-binding protein CH43_513 ENOG4105ZTC transcriptional activator, Ogr delta CH43_515 ENOG4105DFP Integrase CH43_517 ENOG4105T16 Transcriptional regulator (AraC family) CH43_518 ENOG4107RNG ABC transporter CH43_52 ENOG4105CJT Mannose-1-phosphate guanylyltransferase CH43_520 ENOG4105DFW ABC transporter CH43_522 ENOG4105CMG Carbohydrate kinase CH43_524 ENOG4108TTM chaperone CH43_527 ENOG4106EAR Fimbrial protein CH43_528 ENOG4105MEV Acyl-transferase CH43_53 ENOG4105C30 Nad-dependent epimerase dehydratase CH43_530 ENOG4105DQ6 Transposase CH43_531 ENOG4105SYT Methylenetetrahydrofolate reductase CH43_532 ENOG4105CFH Aspartokinase CH43_533 ENOG4105C28 cystathionine CH43_535 ENOG4108Z12 YiaAB two helix domain-containing protein CH43_537 ENOG4105C25 Primosomal protein n' CH43_539 ENOG4105ETE Transcriptional regulator (LacI family CH43_54 ENOG4105C0K Gdp-mannose 4,6-dehydratase CH43_540 ENOG41063M6 Cell Division Protein CH43_543 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CH43_547 ENOG4108MBX Secretion Protein CH43_548 ENOG4108JJA ABC, transporter CH43_55 ENOG4105C0K Gdp-mannose 4,6-dehydratase CH43_551 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CH43_552 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CH43_553 ENOG4105CBT Fructose-1,6-bisphosphatase CH43_554 ENOG4105DP0 ferredoxin-NADP reductase CH43_555 ENOG4108VTS Membrane CH43_556 ENOG4105EBK exported protein CH43_558 ENOG4107F9Y LysR family transcriptional regulator CH43_56 ENOG4108TJN glycosyl transferase group 1 CH43_560 ENOG4105JSC dimethylmenaquinone methyltransferase CH43_564 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein CH43_569 ENOG4105FMW periplasmic CH43_570 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH43_571 ENOG4105E0F Histidine kinase CH43_572 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CH43_573 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CH43_574 ENOG4105D7W serine acetyltransferase CH43_577 ENOG4105VW4 glutaredoxin 3 CH43_578 ENOG4107YZP Rhodanese domain protein CH43_580 ENOG41063SB peptidase CH43_581 ENOG4105PXI polysaccharide deacetylase CH43_582 ENOG4105PXI polysaccharide deacetylase CH43_584 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CH43_586 ENOG4105XA0 heptosyltransferase ii CH43_587 ENOG4105D16 lipopolysaccharide heptosyltransferase i CH43_588 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase CH43_592 ENOG4105W0E 50S ribosomal protein L33 CH43_595 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CH43_600 ENOG4105DSJ YicC domain protein CH43_601 ENOG4105EN6 Membrane CH43_602 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) CH43_605 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CH43_606 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase CH43_607 ENOG4105CB5 ATP-dependent DNA helicase recG CH43_608 ENOG4105D6U Sodium Glutamate Symporter CH43_609 ENOG4105C2W permease CH43_610 ENOG4105JV1 AsmA family CH43_611 ENOG4105SUU thioesterase domain CH43_615 ENOG4107S2Z UPF0761 membrane protein CH43_616 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 CH43_618 ENOG4105C5F glutamine synthetase CH43_619 ENOG4105CUX Signal transduction histidine kinase CH43_620 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH43_621 ENOG4105D4P Coproporphyrinogen iii oxidase CH43_624 ENOG4105C2M dna polymerase I CH43_625 ENOG4108Z33 Thiol disulfide Interchange Protein CH43_626 ENOG4105E27 serine threonine protein kinase CH43_627 ENOG4105PC1 Conserved Protein CH43_629 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b CH43_63 ENOG4108SMP Nad-dependent epimerase dehydratase CH43_635 ENOG4107EJG GntR family transcriptional regulator CH43_637 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH43_64 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CH43_645 ENOG4108VVK transcriptional Regulator, AsnC CH43_646 ENOG4105QTB Flavodoxin CH43_649 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation CH43_65 ENOG4105FAW cDP-glucose 4,6-dehydratase CH43_651 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) CH43_659 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CH43_66 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase CH43_660 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) CH43_661 ENOG4105C8U phosphate abc transporter CH43_662 ENOG4105E2Z phosphate ABC transporter (Permease CH43_666 ENOG4106PMH Extracellular solute-binding protein family 3 CH43_667 ENOG4105EAD ABC transporter CH43_668 ENOG4105DRP amino acid AbC transporter CH43_669 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 CH43_67 ENOG4108EX3 reductase CH43_670 ENOG4105C7N Xanthine uracil vitamin C permease CH43_675 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CH43_678 ENOG4105VG0 50S ribosomal protein l34 CH43_681 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CH43_682 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) CH43_683 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH43_684 ENOG410667J hydrolase CH43_685 ENOG4105DQ6 Transposase CH43_688 ENOG4105C7B Threonine dehydratase CH43_689 ENOG4105D99 atp gtp-binding protein CH43_690 ENOG4105D99 atp gtp-binding protein CH43_691 ENOG4105R2A (LipO)protein CH43_695 ENOG4105JKW Valine--pyruvate aminotransferase CH43_697 ENOG4107T9C Alpha amylase catalytic region CH43_700 ENOG4108ZG0 Ompa motb domain protein CH43_702 ENOG4108R3E Dna-3-methyladenine glycosylase i CH43_706 ENOG4106JH6 (LipO)protein CH43_707 ENOG4105CTS PTS system mannitol-specific CH43_709 ENOG4105E61 Mannitol repressor protein CH43_711 ENOG4108YYI Protein of unknown function (DUF2810) CH43_715 ENOG4105C8Q Methyl-accepting chemotaxis CH43_716 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CH43_718 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH43_719 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH43_720 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CH43_721 ENOG4108MG3 formate dehydrogenase CH43_724 ENOG4105EM7 Selenocysteine-specific translation elongation factor CH43_725 ENOG4105D13 transposase CH43_73 ENOG4107QMP dna polymerase iii subunits gamma and tau CH43_731 ENOG4105DQ6 Transposase CH43_733 ENOG4105E98 transcriptional regulator DeoR family CH43_737 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CH43_738 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) CH43_740 ENOG4105MJ2 Competence protein CH43_742 ENOG4105RID UPF0379 protein yhcN CH43_744 ENOG4105CE1 Ferrous iron transport protein b CH43_745 ENOG4105XFK Ferrous iron transport protein A CH43_746 ENOG4105BZM domain protein CH43_747 ENOG4108RRZ Transcription elongation factor GreB CH43_748 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH43_749 ENOG4105E0F Histidine kinase CH43_75 ENOG4105WD1 Membrane CH43_752 ENOG4105VEJ Heat shock protein CH43_753 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 CH43_754 ENOG4105DQY intracellular growth attenuator CH43_756 ENOG4107RK2 ADP-ribose diphosphatase NudE CH43_757 ENOG4108JQC penicillin-binding protein 1A CH43_762 ENOG4105E4G Type IV pilus CH43_767 ENOG4105DJV ribulose-phosphate 3-epimerase CH43_768 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) CH43_769 ENOG4105C31 Tryptophanyl-tRNA synthetase CH43_77 ENOG4105EGS Mechanosensitive ion channel CH43_771 ENOG4107V9H nitrite transporter CH43_772 ENOG4105WZK nitrite reductase NADPH small subunit CH43_773 ENOG4107QZF nitrite reductase NADPH large subunit CH43_774 ENOG4105DZC cytosine deaminase CH43_777 ENOG41060NJ transcriptional regulator CH43_778 ENOG4105F8D glycoside hydrolase family 4 CH43_779 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CH43_78 ENOG41090EX DsrE family CH43_780 ENOG4105D7A ATP-binding protein CH43_782 ENOG4105C8Y Acetylornithine aminotransferase CH43_783 ENOG410613R integral membrane protein, YccS YhfK family CH43_785 ENOG4108UKZ OsmC family CH43_787 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) CH43_789 ENOG4105DNZ Alpha Beta Hydrolase CH43_79 ENOG4108IG5 Transcriptional regulator CH43_791 ENOG4106FTQ Taurine ABC transporter, periplasmic CH43_793 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CH43_794 ENOG4105E2B Taurine dioxygenase CH43_797 ENOG4105K64 Glycosyl transferase, family 2 CH43_798 ENOG4105C5H ABC transporter CH43_80 ENOG4105C1P efflux transporter, rnd family, mfp subunit CH43_801 ENOG4105VKU nucleicacid-binding protein CH43_802 ENOG4108YZY peptidylprolyl cis-trans isomerase CH43_804 ENOG4108V1T peptidylprolyl cis-trans isomerase CH43_805 ENOG4105WWK YheO domain protein CH43_81 ENOG4105BZS acriflavin resistance protein CH43_810 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) CH43_813 ENOG4108RS6 transposase CH43_821 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) CH43_823 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) CH43_824 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) CH43_826 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal CH43_83 ENOG4105YK5 50S ribosomal protein L36 CH43_835 ENOG4105VPB 50S ribosomal protein L30 CH43_837 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CH43_838 ENOG41067V7 50S ribosomal protein L36 CH43_841 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) CH43_844 ENOG4105W1Y Transcriptional regulator CH43_845 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system CH43_847 ENOG4105C1A potassium transporter peripheral membrane CH43_85 ENOG4108UKR Biofilm formation regulator YbaJ CH43_851 ENOG4105C79 DNA protecting protein DprA CH43_853 ENOG4108WI1 Dna topoisomerase CH43_856 ENOG4108Z0R Transferase CH43_86 ENOG4105KF5 hemolysin expression-modulating protein CH43_863 ENOG4105CMM transposase CH43_869 ENOG41062QD Membrane CH43_87 ENOG41080UX Methyltransferase CH43_871 ENOG4105CK2 sodium dicarboxylate symporter CH43_872 ENOG4105WH1 Two component transcriptional regulator luxr family CH43_873 ENOG4105BZU Histidine kinase CH43_88 ENOG4108MNP Glycoprotein polysaccharide metabolism CH43_885 ENOG4108JIR Flagellum-specific ATP synthase CH43_888 ENOG41063Q7 Type III secretion system protein CH43_889 ENOG4108HHI Type III secretion system protein CH43_89 ENOG4105C29 acyl-CoA thioesterase CH43_890 ENOG41083GP type iii secretion CH43_891 ENOG4108TN6 type iii secretion CH43_892 ENOG4108IUF type iii secretion CH43_893 ENOG41066VF YeeE YedE family protein CH43_894 ENOG4105KSU Redox protein CH43_895 ENOG4105EQ2 LysR family Transcriptional regulator CH43_896 ENOG4105C44 Serine transporter CH43_897 ENOG4105C28 cystathionine CH43_899 ENOG4105EHG Permease protein CH43_90 ENOG4105BZU Histidine kinase CH43_900 ENOG4107R4I Periplasmic binding protein CH43_901 ENOG4106QJH hemin transport protein CH43_902 ENOG4107ENK receptor CH43_903 ENOG4107F3C Hemin uptake protein CH43_905 ENOG41090JE Utilization Protein CH43_906 ENOG4105D4P Coproporphyrinogen iii oxidase CH43_91 ENOG4108YZA Nitrogen regulatory protein pii CH43_910 ENOG4105DAX Pfam:DUF2983 CH43_92 ENOG4105BZ1 (ABC) transporter CH43_922 ENOG4108S1B Periplasmic chaperone protein CH43_93 ENOG4105BZ1 (ABC) transporter CH43_931 ENOG41080IJ Diacylglycerol kinase CH43_933 ENOG4105MYN Zinc uptake regulation protein CH43_934 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CH43_935 ENOG4105P4Z Phage shock protein G CH43_936 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CH43_937 ENOG4105CDU Replicative dna helicase CH43_938 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CH43_939 ENOG4105CGF Aromatic amino acid aminotransferase CH43_94 ENOG4108XM1 transcriptional regulator AsnC family CH43_940 ENOG4105MSB protein, conserved in bacteria CH43_941 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CH43_942 ENOG4108UUM single-stranded DNA-binding protein CH43_944 ENOG4105C0A alcohol dehydrogenase CH43_95 ENOG4105C6T cysteine synthase CH43_958 ENOG4108SIC Transcriptional regulator CH43_959 ENOG4105BZ8 glutamate synthase CH43_960 ENOG4108RC0 Electron transport protein CH43_961 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH43_964 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH43_969 ENOG4108ZVF (LipO)protein CH43_97 ENOG4108NFA extracellular solute-binding protein CH43_970 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CH43_972 ENOG4105KPY Small multidrug resistance protein CH43_973 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) CH43_978 ENOG4105EGS Mechanosensitive ion channel CH43_981 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) CH43_984 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CH43_985 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) CH43_986 ENOG4105K8N protein family UPF0079, ATPase CH43_987 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CH43_99 ENOG4108TGP Thioesterase superfamily protein CH43_991 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CH43_992 ENOG4107QJR hflk protein CH43_993 ENOG4105EPW hflc protein CH43_997 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CH43_998 ENOG4105C2N RNA methyltransferase TrmH family group 3 CH43_999 ENOG4105CSU acyl-Coa dehydrogenase