locus-tag	class	description
CH43_10	COG0671	phosphoesterase, PA-phosphatase related
CH43_10	COG2453	phosphatase
CH43_100	COG1555	photosystem II stabilization
CH43_1000	COG3650	response to hydrogen peroxide
CH43_1003	COG2194	sulfuric ester hydrolase activity
CH43_1004	COG2197	response regulator
CH43_1005	COG3851	Histidine kinase
CH43_1006	COG2271	Major facilitator Superfamily
CH43_101	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH43_1010	COG2831	hemolysin activation secretion protein
CH43_1012	COG0747	negative chemotaxis
CH43_1013	COG0601	transmembrane transport
CH43_1014	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH43_1015	COG0444	Belongs to the ABC transporter superfamily
CH43_1016	COG4608	Belongs to the ABC transporter superfamily
CH43_1017	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH43_1018	COG2199	diguanylate cyclase activity
CH43_1018	COG2200	EAL domain
CH43_1019	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH43_102	COG1943	Transposase
CH43_1024	COG0612	Peptidase, M16
CH43_1025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH43_1026	COG1942	4-Oxalocrotonate Tautomerase
CH43_1027	COG2200	EAL domain
CH43_1028	COG2982	Protein involved in outer membrane biogenesis
CH43_1029	COG2134	cdp-diacylglycerol pyrophosphatase
CH43_1030	COG1295	ribonuclease BN
CH43_1035	COG1929	Belongs to the glycerate kinase type-1 family
CH43_1036	COG2610	gluconate transmembrane transporter activity
CH43_1037	COG3835	regulator
CH43_1038	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH43_1039	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH43_104	COG0776	regulation of translation
CH43_1040	COG0339	signal peptide processing
CH43_1044	COG0589	response to stress
CH43_1047	COG0306	phosphate transporter
CH43_1048	COG2081	HI0933 family
CH43_105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH43_1051	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_1052	COG1879	ABC-type sugar transport system periplasmic component
CH43_1054	COG0191	fructose-bisphosphate aldolase activity
CH43_1056	COG0745	RESPONSE REGULATOR receiver
CH43_1058	COG1741	Belongs to the pirin family
CH43_1061	COG2610	gluconate transmembrane transporter activity
CH43_1062	COG3265	gluconokinase activity
CH43_1066	COG2095	MarC family integral membrane protein
CH43_1067	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH43_1073	COG3275	phosphorelay sensor kinase activity
CH43_1076	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CH43_1078	COG0058	SHG alpha-glucan phosphorylase activity
CH43_1079	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH43_1082	COG2801	Transposase and inactivated derivatives
CH43_1086	COG0513	Belongs to the DEAD box helicase family
CH43_1089	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH43_1092	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH43_1097	COG3153	acetyltransferase
CH43_11	COG2267	carboxylic ester hydrolase activity
CH43_110	COG0271	Belongs to the BolA IbaG family
CH43_1101	COG1653	transport
CH43_1103	COG0395	ABC-type sugar transport system, permease component
CH43_1104	COG3842	ATPase activity
CH43_1107	COG0702	epimerase
CH43_1108	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH43_1109	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH43_111	COG3056	Lipoprotein
CH43_1110	COG3454	Phosphonate metabolism
CH43_1111	COG4778	phosphonate C-P lyase system protein PhnL
CH43_1112	COG4107	phosphonate C-P lyase system protein PhnK
CH43_1113	COG3627	carbon phosphorus lyase activity
CH43_1114	COG3626	phosphonate metabolism
CH43_1115	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH43_1116	COG3624	Phosphonate C-P lyase system protein PhnG
CH43_1117	COG2188	Transcriptional regulator
CH43_112	COG2223	nitrite transmembrane transporter activity
CH43_1121	COG4608	Belongs to the ABC transporter superfamily
CH43_1122	COG0444	Belongs to the ABC transporter superfamily
CH43_1123	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH43_1124	COG0601	transmembrane transport
CH43_1127	COG2731	YhcH YjgK YiaL family protein
CH43_1128	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CH43_1129	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH43_1131	COG0525	valine-tRNA ligase activity
CH43_1132	COG2927	DNA polymerase III (CHI subunit)
CH43_1134	COG0795	lipopolysaccharide-transporting ATPase activity
CH43_1135	COG0795	lipopolysaccharide-transporting ATPase activity
CH43_1137	COG0582	viral genome integration into host DNA
CH43_114	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH43_1142	COG1401	restriction endodeoxyribonuclease activity
CH43_1144	COG2963	transposase activity
CH43_115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH43_1154	COG4269	membrane
CH43_1156	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH43_1157	COG2207	Transcriptional regulator
CH43_1158	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH43_1159	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH43_116	COG1845	cytochrome c oxidase, subunit III
CH43_1160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_1160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_1160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH43_1168	COG2390	Transcriptional regulator
CH43_117	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH43_1170	COG0859	PFAM glycosyl transferase family 9
CH43_1173	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH43_1174	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH43_1177	COG3706	GGDEF domain
CH43_1181	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH43_1182	COG0456	acetyltransferase
CH43_1184	COG2823	Periplasmic or secreted lipoprotein
CH43_1186	COG4667	esterase of the alpha-beta hydrolase superfamily
CH43_1187	COG0084	hydrolase, TatD family'
CH43_1188	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH43_1189	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH43_119	COG2814	Major facilitator Superfamily
CH43_1193	COG3726	membrane protein affecting hemolysin expression
CH43_1194	COG0560	Phosphoserine phosphatase
CH43_1199	COG0488	(ABC) transporter
CH43_1200	COG2885	chlorophyll binding
CH43_1201	COG2199	diguanylate cyclase activity
CH43_1204	COG0741	lytic transglycosylase activity
CH43_1206	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH43_1207	COG2207	Transcriptional regulator
CH43_1207	COG3708	Transcriptional regulator
CH43_121	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH43_1210	COG3045	CreA protein
CH43_1211	COG0745	RESPONSE REGULATOR receiver
CH43_1219	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH43_122	COG0693	protein deglycase activity
CH43_1222	COG1584	GPR1 FUN34 yaaH family protein
CH43_1226	COG0583	DNA-binding transcription factor activity
CH43_1228	COG0196	riboflavin kinase activity
CH43_1231	COG1047	Peptidyl-prolyl cis-trans
CH43_1234	COG0505	Belongs to the CarA family
CH43_1235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH43_1236	COG1280	lysine exporter protein (LysE YggA)
CH43_1237	COG2966	Psort location CytoplasmicMembrane, score
CH43_1239	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH43_1244	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH43_1245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH43_1247	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH43_1248	COG0564	pseudouridine synthase activity
CH43_125	COG0142	geranyltranstransferase activity
CH43_1258	COG3501	Rhs element vgr protein
CH43_1265	COG2885	chlorophyll binding
CH43_1265	COG3047	cAMP biosynthetic process
CH43_1269	COG0417	DNA replication proofreading
CH43_1270	COG0586	Pfam SNARE associated Golgi protein
CH43_1272	COG1178	ABC-type Fe3 transport system permease component
CH43_1273	COG4143	(ABC) transporter
CH43_1276	COG2814	Major facilitator Superfamily
CH43_1279	COG0473	3-isopropylmalate dehydrogenase activity
CH43_128	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH43_1283	COG1022	Amp-dependent synthetase and ligase
CH43_1284	COG3328	transposase activity
CH43_1285	COG0028	Belongs to the TPP enzyme family
CH43_1287	COG1943	Transposase
CH43_1288	COG1609	Transcriptional regulator
CH43_129	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH43_1293	COG3116	cell division
CH43_1294	COG0768	penicillin binding
CH43_1295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH43_1296	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH43_1299	COG0772	Belongs to the SEDS family
CH43_13	COG4589	Belongs to the CDS family
CH43_1303	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH43_1304	COG0849	cell division
CH43_1305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH43_1310	COG0494	nUDIX hydrolase
CH43_1315	COG0237	dephospho-CoA kinase activity
CH43_1317	COG1459	type II secretion system
CH43_1318	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH43_1319	COG4969	Belongs to the N-Me-Phe pilin family
CH43_132	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH43_132	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH43_1321	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH43_1322	COG3725	Membrane protein required for beta-lactamase induction
CH43_1323	COG1113	amino acid transport
CH43_1324	COG2186	Transcriptional regulator
CH43_1325	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH43_1326	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH43_1327	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH43_1328	COG1943	Transposase
CH43_1329	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH43_1331	COG0697	spore germination
CH43_1335	COG2132	Multicopper oxidase
CH43_1336	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH43_1337	COG0288	reversible hydration of carbon dioxide
CH43_1338	COG1131	(ABC) transporter
CH43_1339	COG0842	Transport permease protein
CH43_1341	COG0726	polysaccharide deacetylase
CH43_1345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH43_1346	COG0617	tRNA 3'-terminal CCA addition
CH43_1347	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH43_1348	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH43_1350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH43_1351	COG1643	Atp-dependent helicase
CH43_1352	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH43_1353	COG1120	ATPase activity
CH43_1354	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH43_1355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH43_1359	COG2860	membrane
CH43_1361	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH43_1363	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH43_1364	COG4999	Histidine kinase
CH43_1364	COG3850	Histidine kinase
CH43_1364	COG3437	response regulator, receiver
CH43_1364	COG2205	protein histidine kinase activity
CH43_1365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH43_1366	COG3956	TIGRFAM MazG family protein
CH43_137	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH43_1370	COG0602	queuosine metabolic process
CH43_1371	COG0720	synthase
CH43_138	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH43_1382	COG0529	Catalyzes the synthesis of activated sulfate
CH43_1385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CH43_139	COG1862	Preprotein translocase
CH43_1390	COG4942	peptidase
CH43_1390	COG1388	LysM domain
CH43_1391	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH43_1392	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH43_1393	COG0698	ribose 5-phosphate isomerase
CH43_1394	COG1063	alcohol dehydrogenase
CH43_1395	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_1396	COG2376	Dihydroxyacetone kinase
CH43_1399	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH43_14	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH43_1403	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH43_1404	COG1858	cytochrome C peroxidase
CH43_1406	COG4771	TonB-dependent receptor
CH43_1408	COG0024	Methionine aminopeptidase
CH43_141	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CH43_1410	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH43_1410	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH43_1411	COG1070	Carbohydrate kinase
CH43_1412	COG3623	hexulose-6-phosphate isomerase
CH43_1413	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_1414	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_1415	COG1129	ABC transporter
CH43_1417	COG1349	DNA-binding transcription factor activity
CH43_1418	COG0235	Class ii aldolase
CH43_1419	COG0243	molybdopterin cofactor binding
CH43_142	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CH43_1420	COG0437	4 iron, 4 sulfur cluster binding
CH43_1421	COG3302	dmso reductase anchor subunit
CH43_1422	COG3381	protein complex oligomerization
CH43_1423	COG3038	cytochrome b561
CH43_1424	COG3783	Cytochrome b(562)
CH43_1428	COG1129	ABC transporter
CH43_1429	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_143	COG0450	alkyl hydroperoxide reductase
CH43_1430	COG3959	Transketolase, thiamine diphosphate binding domain
CH43_1431	COG3958	Transketolase
CH43_1432	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH43_1439	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH43_1440	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH43_1444	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH43_1445	COG1238	metal cluster binding
CH43_1446	COG2918	glutathione biosynthetic process
CH43_1448	COG4536	flavin adenine dinucleotide binding
CH43_1449	COG4137	Cytochrome C assembly protein
CH43_1450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH43_1455	COG3137	Salt-induced outer membrane protein
CH43_1456	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH43_1457	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH43_1458	COG3279	Response regulator of the LytR AlgR family
CH43_1459	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH43_1462	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH43_1463	COG1605	Chorismate mutase
CH43_1463	COG0287	Prephenate dehydrogenase
CH43_1464	COG0077	Prephenate dehydratase
CH43_1464	COG1605	Chorismate mutase
CH43_1466	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH43_1467	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH43_1468	COG0564	pseudouridine synthase activity
CH43_147	COG0366	Alpha amylase catalytic
CH43_1470	COG0542	response to heat
CH43_1481	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH43_1482	COG2224	Isocitrate lyase
CH43_1484	COG1414	Transcriptional regulator
CH43_1489	COG0527	aspartate kinase activity
CH43_149	COG1114	Component of the transport system for branched-chain amino acids
CH43_1492	COG3833	ABC-type maltose transport systems, permease component
CH43_1493	COG1175	transmembrane transport
CH43_1504	COG2801	Transposase and inactivated derivatives
CH43_151	COG5002	protein histidine kinase activity
CH43_152	COG0745	RESPONSE REGULATOR receiver
CH43_1520	COG3501	Rhs element vgr protein
CH43_1523	COG3209	COG3209 Rhs family protein
CH43_1529	COG3501	Rhs element vgr protein
CH43_153	COG0420	3'-5' exonuclease activity
CH43_1531	COG3209	COG3209 Rhs family protein
CH43_1534	COG0673	inositol 2-dehydrogenase activity
CH43_1535	COG2207	Transcriptional regulator
CH43_1535	COG1917	Cupin 2, conserved barrel domain protein
CH43_1536	COG1869	D-ribose catabolic process
CH43_1537	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH43_1539	COG0431	NADPH-dependent FMN reductase
CH43_154	COG0419	ATPase involved in DNA repair
CH43_1540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH43_1542	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH43_1544	COG3077	Addiction module antitoxin, RelB DinJ family
CH43_1545	COG2252	PERMEase
CH43_1546	COG0025	NhaP-type Na H and K H
CH43_1548	COG1560	Kdo2-lipid A biosynthetic process
CH43_155	COG1940	carbohydrate kinase activity
CH43_1550	COG1129	ABC transporter
CH43_1551	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_1553	COG1069	ribulokinase activity
CH43_1555	COG0625	glutathione transferase activity
CH43_1558	COG1943	Transposase
CH43_1559	COG1278	Cold shock
CH43_1560	COG1278	Cold shock
CH43_1561	COG3133	Outer membrane lipoprotein
CH43_1562	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH43_1564	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH43_1568	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH43_1569	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH43_1571	COG4145	pantothenate transmembrane transporter activity
CH43_1572	COG3924	membrane
CH43_1574	COG0439	Biotin carboxylase
CH43_1575	COG0511	ligase activity, forming carbon-carbon bonds
CH43_1578	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH43_1579	COG0604	alcohol dehydrogenase
CH43_1580	COG2199	diguanylate cyclase activity
CH43_1580	COG2200	EAL domain
CH43_1581	COG1077	Cell shape determining protein MreB Mrl
CH43_1582	COG1792	Involved in formation and maintenance of cell shape
CH43_1583	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH43_1585	COG1530	ribonuclease E activity
CH43_1586	COG3164	Protein of unknown function
CH43_1587	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH43_1588	COG0312	modulator of DNA gyrase
CH43_1598	COG0583	DNA-binding transcription factor activity
CH43_160	COG2226	methyltransferase
CH43_1602	COG1012	belongs to the aldehyde dehydrogenase family
CH43_1605	COG2732	(Barnase) inhibitor
CH43_1607	COG0312	modulator of DNA gyrase
CH43_1609	COG3783	Cytochrome b(562)
CH43_1610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH43_1611	COG0366	Alpha amylase catalytic
CH43_1612	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH43_1612	COG1263	PTS System
CH43_1613	COG1609	Transcriptional regulator
CH43_1618	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_1620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_1622	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH43_1623	COG1137	ATPase activity
CH43_1624	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH43_1625	COG3117	lipopolysaccharide transmembrane transporter activity
CH43_1626	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH43_1627	COG0517	IMP dehydrogenase activity
CH43_1627	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH43_1628	COG0530	calcium, potassium:sodium antiporter activity
CH43_1629	COG1127	ABC transporter
CH43_1630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH43_1631	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH43_1632	COG2854	intermembrane phospholipid transfer
CH43_1633	COG3113	response to antibiotic
CH43_1634	COG5007	Belongs to the BolA IbaG family
CH43_1636	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH43_1637	COG1943	Transposase
CH43_1638	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH43_1639	COG3105	Protein conserved in bacteria
CH43_1640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH43_1643	COG0625	glutathione transferase activity
CH43_1644	COG2969	positive regulation of protein catabolic process
CH43_1646	COG0493	'glutamate synthase
CH43_1647	COG0070	glutamate synthase
CH43_1647	COG0069	glutamate synthase activity
CH43_1647	COG0067	glutamate synthase
CH43_1648	COG1242	4 iron, 4 sulfur cluster binding
CH43_1649	COG5002	protein histidine kinase activity
CH43_1649	COG0784	Response regulator, receiver
CH43_1649	COG2198	Histidine kinase
CH43_1650	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH43_1652	COG2823	Periplasmic or secreted lipoprotein
CH43_1656	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH43_1657	COG1741	Belongs to the pirin family
CH43_1658	COG0583	DNA-binding transcription factor activity
CH43_1659	COG0435	Glutathione S-transferase
CH43_1660	COG2259	Doxx family
CH43_1662	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH43_1663	COG4575	ribosome binding
CH43_1666	COG0586	Pfam SNARE associated Golgi protein
CH43_1672	COG0246	Mannitol dehydrogenase
CH43_1673	COG2721	sulfolactate sulfo-lyase activity
CH43_1675	COG1943	Transposase
CH43_1678	COG0673	inositol 2-dehydrogenase activity
CH43_1679	COG1451	nucleotide metabolic process
CH43_1682	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH43_1682	COG1902	pentaerythritol trinitrate reductase activity
CH43_1683	COG3247	response to pH
CH43_1686	COG4245	von Willebrand factor, type A
CH43_1689	COG4245	von Willebrand factor, type A
CH43_1690	COG2831	hemolysin activation secretion protein
CH43_1691	COG3210	domain, Protein
CH43_1693	COG3210	domain, Protein
CH43_1695	COG3210	domain, Protein
CH43_1699	COG3842	ATPase activity
CH43_1700	COG3459	Glycosyltransferase 36 associated
CH43_1701	COG1609	Transcriptional regulator
CH43_1702	COG1653	transport
CH43_1704	COG0395	ABC-type sugar transport system, permease component
CH43_1708	COG1289	transmembrane transporter activity
CH43_171	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH43_1716	COG0251	oxidation-reduction process
CH43_1734	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH43_1735	COG0358	DNA primase activity
CH43_1739	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH43_1742	COG4991	sh3 domain protein
CH43_1743	COG3025	triphosphatase activity
CH43_1746	COG0531	amino acid
CH43_175	COG1477	protein flavinylation
CH43_1750	COG3384	dioxygenase
CH43_1751	COG0754	glutathionylspermidine amidase activity
CH43_1754	COG1538	Outer membrane efflux protein
CH43_1755	COG0494	nUDIX hydrolase
CH43_1756	COG3151	Protein conserved in bacteria
CH43_1757	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH43_1758	COG3150	esterase
CH43_1759	COG0187	DNA topoisomerase II activity
CH43_1760	COG0583	DNA-binding transcription factor activity
CH43_1761	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH43_1762	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH43_1763	COG0204	Acyl-transferase
CH43_1764	COG2132	Multicopper oxidase
CH43_1767	COG0656	L-ascorbic acid biosynthetic process
CH43_1768	COG1979	alcohol dehydrogenase
CH43_1769	COG2207	Transcriptional regulator
CH43_1770	COG0586	Pfam SNARE associated Golgi protein
CH43_1771	COG0626	cystathionine gamma-synthase activity
CH43_1772	COG0811	peptide transport
CH43_1774	COG0848	biopolymer transport protein
CH43_1784	COG4964	Belongs to the GSP D family
CH43_1785	COG4964	Belongs to the GSP D family
CH43_179	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH43_1793	COG4592	Periplasmic binding protein
CH43_1797	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH43_1798	COG1684	flagellar biosynthetic protein fliR
CH43_1799	COG1987	bacterial-type flagellum assembly
CH43_180	COG1805	sodium ion transport
CH43_1803	COG2204	response regulator
CH43_181	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH43_1812	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH43_1813	COG1815	bacterial-type flagellum-dependent cell motility
CH43_1814	COG1558	bacterial-type flagellum-dependent cell motility
CH43_1815	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH43_1816	COG1749	Flagellar hook protein flgE
CH43_1817	COG4787	bacterial-type flagellum-dependent cell motility
CH43_1818	COG4786	Flagellar basal body rod
CH43_1819	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH43_182	COG0121	glutamine amidotransferase
CH43_1820	COG1706	bacterial-type flagellum-dependent cell motility
CH43_1822	COG1256	bacterial-type flagellum assembly
CH43_1826	COG3710	Transcriptional regulator
CH43_183	COG3034	peptidoglycan biosynthetic process
CH43_1831	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH43_1836	COG1191	sigma factor activity
CH43_1837	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH43_1842	COG3133	Outer membrane lipoprotein
CH43_1845	COG2801	Transposase and inactivated derivatives
CH43_1846	COG2211	Major facilitator Superfamily
CH43_185	COG1960	acyl-CoA dehydrogenase activity
CH43_1856	COG3916	Acyl-homoserine-lactone synthase
CH43_1857	COG2771	luxR family
CH43_1875	COG1662	PFAM IS1 transposase
CH43_1879	COG1982	Orn Lys Arg decarboxylase major
CH43_188	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH43_1880	COG1879	ABC-type sugar transport system periplasmic component
CH43_1881	COG1129	ABC transporter
CH43_1882	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_1883	COG4774	siderophore transport
CH43_1887	COG1194	a g-specific adenine glycosylase
CH43_1889	COG3171	Protein conserved in bacteria
CH43_1890	COG2066	Belongs to the glutaminase family
CH43_1893	COG1073	alpha beta
CH43_1893	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH43_1893	COG3064	Membrane
CH43_1894	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH43_1895	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH43_1897	COG0762	integral membrane protein
CH43_1898	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH43_1899	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH43_1900	COG2805	Type II/IV secretion system protein
CH43_1902	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH43_1905	COG0189	ligase activity
CH43_1906	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH43_1907	COG2356	endonuclease I
CH43_1911	COG1166	arginine decarboxylase activity
CH43_1913	COG0501	Belongs to the peptidase M48B family
CH43_1914	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH43_1918	COG0191	fructose-bisphosphate aldolase activity
CH43_1923	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH43_1924	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH43_1925	COG1943	Transposase
CH43_1926	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH43_1929	COG0006	proline dipeptidase activity
CH43_1930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH43_1931	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH43_1937	COG5295	Hep Hag repeat protein
CH43_1939	COG1272	protein, Hemolysin III
CH43_1942	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH43_1943	COG0745	RESPONSE REGULATOR receiver
CH43_1944	COG2205	protein histidine kinase activity
CH43_1945	COG4452	Inner membrane protein CreD
CH43_1946	COG0716	FMN binding
CH43_1947	COG4974	Belongs to the 'phage' integrase family
CH43_1948	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH43_1949	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH43_1953	COG0582	viral genome integration into host DNA
CH43_1958	COG2944	sequence-specific DNA binding
CH43_196	COG0436	Aminotransferase
CH43_1975	COG1695	Transcriptional regulator
CH43_1976	COG0791	NLP P60 protein
CH43_1978	COG1879	ABC-type sugar transport system periplasmic component
CH43_1979	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_1980	COG1129	ABC transporter
CH43_1982	COG2182	Extracellular solute-binding protein
CH43_1983	COG1175	transmembrane transport
CH43_1984	COG3833	ABC-type maltose transport systems, permease component
CH43_1985	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH43_1988	COG1263	PTS System
CH43_1988	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH43_199	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH43_1992	COG2271	Major facilitator Superfamily
CH43_1996	COG0191	fructose-bisphosphate aldolase activity
CH43_1998	COG3119	arylsulfatase activity
CH43_1999	COG0641	radical SAM
CH43_2001	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_2003	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_2004	COG3716	PTS system mannose fructose sorbose family IID component
CH43_2005	COG3715	PTS system
CH43_2006	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH43_2007	COG2222	sugar isomerase
CH43_2009	COG1349	DNA-binding transcription factor activity
CH43_2010	COG3119	arylsulfatase activity
CH43_2018	COG0288	reversible hydration of carbon dioxide
CH43_202	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH43_2035	COG3328	transposase activity
CH43_2036	COG3328	transposase activity
CH43_2040	COG0840	transmembrane signaling receptor activity
CH43_2042	COG0583	DNA-binding transcription factor activity
CH43_2043	COG0583	DNA-binding transcription factor activity
CH43_2044	COG2814	Major facilitator Superfamily
CH43_2045	COG1609	Transcriptional regulator
CH43_2046	COG0019	diaminopimelate decarboxylase activity
CH43_2052	COG0667	Aldo Keto reductase
CH43_2063	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH43_2065	COG1074	ATP-dependent DNA helicase activity
CH43_2066	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH43_2070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CH43_2070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CH43_2071	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH43_2075	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH43_2076	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH43_2077	COG2166	iron-sulfur cluster assembly
CH43_2078	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH43_2080	COG0583	DNA-binding transcription factor activity
CH43_2081	COG2363	Small membrane protein
CH43_2083	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH43_2084	COG1611	Belongs to the LOG family
CH43_2087	COG1943	Transposase
CH43_2088	COG3098	single-species biofilm formation
CH43_2089	COG0564	pseudouridine synthase activity
CH43_2094	COG0024	Methionine aminopeptidase
CH43_21	COG2501	S4 domain
CH43_2100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH43_2101	COG0575	Belongs to the CDS family
CH43_2102	COG0750	zinc metalloprotease
CH43_2104	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH43_2108	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH43_211	COG2814	Major facilitator Superfamily
CH43_2110	COG0587	DNA-directed DNA polymerase activity
CH43_2112	COG0346	lactoylglutathione lyase activity
CH43_2113	COG0037	tRNA processing
CH43_2115	COG4568	rho-dependent transcription termination
CH43_2117	COG4681	YaeQ
CH43_2119	COG3015	lipoprotein NlpE involved in copper resistance
CH43_212	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH43_2121	COG1720	tRNA m6t6A37 methyltransferase activity
CH43_2123	COG1464	Belongs to the NlpA lipoprotein family
CH43_2124	COG2011	ABC-type metal ion transport system permease component
CH43_2126	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH43_2132	COG0656	L-ascorbic acid biosynthetic process
CH43_2135	COG0741	lytic transglycosylase activity
CH43_2135	COG1388	LysM domain
CH43_2137	COG2226	methyltransferase
CH43_2139	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH43_214	COG1846	Transcriptional regulator
CH43_2141	COG1953	Uracil, thiamine, allantoin
CH43_2143	COG2113	Glycine betaine
CH43_2144	COG4176	ABC-type proline glycine betaine transport system permease component
CH43_2145	COG4175	Glycine betaine
CH43_2146	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH43_215	COG1566	PFAM secretion protein HlyD family protein
CH43_2154	COG1278	Cold shock
CH43_2155	COG0747	negative chemotaxis
CH43_2157	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH43_2158	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH43_2159	COG1124	(ABC) transporter
CH43_216	COG2814	Major facilitator Superfamily
CH43_2166	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH43_2168	COG4413	Urea transporter
CH43_2169	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH43_217	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH43_2171	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH43_2172	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH43_2173	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH43_2174	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH43_2175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH43_2176	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH43_2177	COG2169	Transcriptional regulator
CH43_2177	COG1917	Cupin 2, conserved barrel domain protein
CH43_218	COG3118	belongs to the thioredoxin family
CH43_2181	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH43_2182	COG0033	Phosphoglucomutase
CH43_2186	COG0745	RESPONSE REGULATOR receiver
CH43_2193	COG3272	Protein of unknown function (DUF1722)
CH43_2195	COG5212	phosphodiesterase
CH43_2196	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH43_2198	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH43_2199	COG1984	allophanate hydrolase subunit 2
CH43_22	COG1943	Transposase
CH43_220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH43_220	COG0045	succinate-CoA ligase (ADP-forming) activity
CH43_220	COG1042	CoA-binding domain protein
CH43_221	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH43_2210	COG0513	Belongs to the DEAD box helicase family
CH43_2212	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH43_2214	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH43_2215	COG3026	antisigma factor binding
CH43_2216	COG3086	response to oxidative stress
CH43_2219	COG0681	Belongs to the peptidase S26 family
CH43_222	COG5544	Lipoprotein
CH43_2223	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH43_2225	COG1943	Transposase
CH43_2226	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH43_2229	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH43_2232	COG1067	ATP-dependent peptidase activity
CH43_2235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH43_2235	COG2885	chlorophyll binding
CH43_2237	COG3070	regulator of competence-specific genes
CH43_2238	COG1289	transmembrane transporter activity
CH43_2239	COG3304	Inner membrane component domain
CH43_2240	COG0210	DNA helicase
CH43_2242	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CH43_2243	COG1832	CoA-binding protein
CH43_2247	COG2920	part of a sulfur-relay system
CH43_2254	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_2256	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH43_2257	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH43_2258	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_2259	COG3425	synthase
CH43_2261	COG1024	Enoyl-CoA hydratase
CH43_2262	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_2264	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH43_2265	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH43_2292	COG0488	(ABC) transporter
CH43_2295	COG0303	'Molybdopterin
CH43_2297	COG1136	(ABC) transporter
CH43_2303	COG0583	DNA-binding transcription factor activity
CH43_2304	COG0477	Major facilitator Superfamily
CH43_2306	COG2311	Membrane
CH43_2309	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH43_2314	COG2949	membrane
CH43_2317	COG1346	cytolysis
CH43_2319	COG2814	Major facilitator Superfamily
CH43_2323	COG1943	Transposase
CH43_2325	COG0489	protein tyrosine kinase activity
CH43_2328	COG2982	Protein involved in outer membrane biogenesis
CH43_2329	COG1253	flavin adenine dinucleotide binding
CH43_2330	COG4114	ferric iron reductase
CH43_2331	COG0076	glutamate decarboxylase activity
CH43_2332	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH43_2335	COG1120	ATPase activity
CH43_2336	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH43_2337	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH43_2338	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH43_2341	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH43_2342	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH43_2344	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH43_2344	COG0140	phosphoribosyl-ATP diphosphatase activity
CH43_2347	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CH43_2348	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH43_2348	COG0131	Imidazoleglycerol-phosphate dehydratase
CH43_235	COG0678	peroxiredoxin activity
CH43_235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH43_2350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH43_2352	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH43_2354	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_2356	COG1129	ABC transporter
CH43_2357	COG0371	Dehydrogenase
CH43_2359	COG0531	amino acid
CH43_236	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH43_2360	COG2925	Exonuclease
CH43_2363	COG1388	LysM domain
CH43_2363	COG1470	cell adhesion involved in biofilm formation
CH43_2364	COG3328	transposase activity
CH43_2365	COG2271	Major facilitator Superfamily
CH43_2366	COG3011	Protein conserved in bacteria
CH43_2367	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_2369	COG4948	Mandelate Racemase Muconate Lactonizing
CH43_2373	COG0534	Mate efflux family protein
CH43_2377	COG3122	Protein conserved in bacteria
CH43_2382	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH43_2387	COG2223	nitrite transmembrane transporter activity
CH43_2393	COG1943	Transposase
CH43_2394	COG1132	(ABC) transporter
CH43_2396	COG2207	Transcriptional regulator
CH43_2403	COG1113	amino acid transport
CH43_2406	COG1278	Cold shock
CH43_2408	COG2226	methyltransferase
CH43_241	COG1629	transport
CH43_2410	COG5001	Diguanylate cyclase
CH43_2410	COG3447	MASE1 domain protein
CH43_2410	COG5002	protein histidine kinase activity
CH43_2414	COG3716	PTS system mannose fructose sorbose family IID component
CH43_2415	COG3715	PTS system
CH43_2416	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH43_2416	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_2417	COG1253	flavin adenine dinucleotide binding
CH43_2418	COG1846	Transcriptional regulator
CH43_2421	COG1012	belongs to the aldehyde dehydrogenase family
CH43_2422	COG3384	dioxygenase
CH43_2424	COG3971	2-oxopent-4-enoate hydratase activity
CH43_2427	COG2368	4-hydroxyphenylacetate
CH43_2428	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH43_2429	COG1760	l-serine dehydratase
CH43_2434	COG0513	Belongs to the DEAD box helicase family
CH43_2435	COG3141	response to X-ray
CH43_2438	COG1770	oligopeptidase
CH43_2441	COG1528	Iron-storage protein
CH43_2442	COG2372	response to copper ion
CH43_2447	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH43_2448	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH43_245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH43_2453	COG3418	PFAM FlgN family protein
CH43_2454	COG2747	anti-sigma28 factor FlgM
CH43_2456	COG1815	bacterial-type flagellum-dependent cell motility
CH43_2457	COG1558	bacterial-type flagellum-dependent cell motility
CH43_2458	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH43_2459	COG1749	Flagellar hook protein flgE
CH43_2461	COG4786	Flagellar basal body rod
CH43_2465	COG1256	bacterial-type flagellum assembly
CH43_2467	COG2390	Transcriptional regulator
CH43_2468	COG3347	Dehydrogenase
CH43_2468	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_2469	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_2471	COG1129	ABC transporter
CH43_2472	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_2473	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH43_2477	COG1987	bacterial-type flagellum assembly
CH43_2482	COG1580	Controls the rotational direction of flagella during chemotaxis
CH43_2484	COG2882	bacterial-type flagellum organization
CH43_2485	COG1157	protein secretion by the type III secretion system
CH43_2487	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH43_2489	COG1677	Flagellar hook-basal body complex protein FliE
CH43_249	COG2801	Transposase and inactivated derivatives
CH43_2492	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH43_2493	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH43_2499	COG1191	sigma factor activity
CH43_25	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH43_2501	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CH43_2508	COG0506	proline dehydrogenase activity
CH43_2508	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH43_2508	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH43_2513	COG2837	iron assimilation
CH43_2516	COG1113	amino acid transport
CH43_2520	COG3136	membrane protein required for alginate biosynthesis
CH43_2522	COG2197	response regulator
CH43_254	COG0195	Participates in both transcription termination and antitermination
CH43_2545	COG3328	transposase activity
CH43_2546	COG3328	transposase activity
CH43_2553	COG0673	inositol 2-dehydrogenase activity
CH43_2555	COG1175	transmembrane transport
CH43_2556	COG0395	ABC-type sugar transport system, permease component
CH43_2569	COG4771	TonB-dependent receptor
CH43_2570	COG1021	2,3-dihydroxybenzoate-AMP ligase
CH43_2574	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH43_2574	COG2226	methyltransferase
CH43_2574	COG3433	isochorismatase activity
CH43_2577	COG1132	(ABC) transporter
CH43_2578	COG2814	Major facilitator Superfamily
CH43_2579	COG1169	isochorismate synthase
CH43_258	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH43_2580	COG0582	viral genome integration into host DNA
CH43_2583	COG3328	transposase activity
CH43_2584	COG3121	Chaperone
CH43_2586	COG3188	usher protein
CH43_2589	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH43_2589	COG2205	protein histidine kinase activity
CH43_2592	COG0427	acetyl-CoA hydrolase
CH43_2593	COG2030	dehydratase
CH43_260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH43_2601	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH43_2602	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH43_2604	COG1349	DNA-binding transcription factor activity
CH43_2605	COG2066	Belongs to the glutaminase family
CH43_261	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH43_2611	COG0577	efflux transmembrane transporter activity
CH43_2611	COG1136	(ABC) transporter
CH43_2613	COG1136	(ABC) transporter
CH43_2613	COG0577	efflux transmembrane transporter activity
CH43_2617	COG0006	proline dipeptidase activity
CH43_2618	COG0457	Tetratricopeptide repeat
CH43_2619	COG1649	PFAM Uncharacterised BCR, COG1649
CH43_2619	COG0726	polysaccharide deacetylase
CH43_2620	COG1215	transferase activity, transferring glycosyl groups
CH43_2621	COG3658	cytochrome
CH43_2624	COG1702	phosphate starvation-inducible protein PhoH
CH43_2625	COG0387	Pfam Sodium calcium exchanger
CH43_2627	COG3850	Histidine kinase
CH43_2628	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH43_263	COG1534	Rna-binding protein
CH43_2637	COG3328	transposase activity
CH43_2638	COG3328	transposase activity
CH43_264	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH43_2645	COG0402	S-adenosylhomocysteine deaminase activity
CH43_2648	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH43_2649	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH43_265	COG2027	D-alanyl-D-alanine carboxypeptidase
CH43_2650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH43_2659	COG3328	transposase activity
CH43_266	COG0745	RESPONSE REGULATOR receiver
CH43_2664	COG0500	methyltransferase
CH43_267	COG0642	Histidine kinase
CH43_2673	COG5002	protein histidine kinase activity
CH43_2677	COG0745	RESPONSE REGULATOR receiver
CH43_2687	COG0012	GTP binding
CH43_269	COG0697	spore germination
CH43_2690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH43_2695	COG2890	protein-(glutamine-N5) methyltransferase activity
CH43_2696	COG3094	Invasion gene expression up-regulator, SirB
CH43_2697	COG2912	Transglutaminase-like superfamily
CH43_2699	COG0659	secondary active sulfate transmembrane transporter activity
CH43_27	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH43_2703	COG3833	ABC-type maltose transport systems, permease component
CH43_2704	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH43_2707	COG3842	ATPase activity
CH43_2708	COG0584	glycerophosphoryl diester phosphodiesterase
CH43_2709	COG1940	carbohydrate kinase activity
CH43_2712	COG3381	protein complex oligomerization
CH43_2715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH43_2716	COG0673	inositol 2-dehydrogenase activity
CH43_2717	COG0728	peptidoglycan biosynthetic process
CH43_272	COG0142	geranyltranstransferase activity
CH43_2721	COG3102	Protein conserved in bacteria
CH43_2725	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH43_2726	COG1801	Protein of unknown function DUF72
CH43_2728	COG0494	nUDIX hydrolase
CH43_2733	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH43_2735	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH43_2736	COG0739	heme binding
CH43_2737	COG1560	Kdo2-lipid A biosynthetic process
CH43_2738	COG0469	pyruvate kinase activity
CH43_2739	COG1737	Transcriptional regulator
CH43_274	COG3423	Transcriptional regulator
CH43_2740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH43_2742	COG0800	Aldolase
CH43_2745	COG0251	oxidation-reduction process
CH43_2746	COG1199	ATP-dependent helicase activity
CH43_2748	COG3065	identical protein binding
CH43_2749	COG0318	PFAM AMP-dependent synthetase and ligase
CH43_2750	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH43_2751	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH43_2752	COG2894	cell division
CH43_2755	COG2951	lytic endotransglycosylase activity
CH43_2756	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH43_2758	COG0582	viral genome integration into host DNA
CH43_278	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH43_2793	COG1943	Transposase
CH43_28	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH43_280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH43_281	COG2105	PFAM AIG2 family protein
CH43_2811	COG1104	cysteine desulfurase activity
CH43_2817	COG2719	SpoVR family
CH43_2819	COG2814	Major facilitator Superfamily
CH43_282	COG2911	Protein conserved in bacteria
CH43_2821	COG0583	DNA-binding transcription factor activity
CH43_2824	COG2766	serine protein kinase
CH43_2825	COG3713	MltA-interacting MipA family protein
CH43_2829	COG3139	Protein of unknown function (DUF1315)
CH43_283	COG0729	surface antigen
CH43_2830	COG1335	isochorismatase
CH43_2831	COG0252	asparaginase activity
CH43_2832	COG0616	signal peptide processing
CH43_2833	COG0778	Nitroreductase
CH43_2834	COG0709	Synthesizes selenophosphate from selenide and ATP
CH43_2835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH43_2837	COG0494	nUDIX hydrolase
CH43_2838	COG0708	Exodeoxyribonuclease III
CH43_2839	COG0583	DNA-binding transcription factor activity
CH43_2840	COG3328	transposase activity
CH43_2844	COG0788	formyltetrahydrofolate deformylase activity
CH43_2846	COG0745	RESPONSE REGULATOR receiver
CH43_2848	COG3328	transposase activity
CH43_285	COG1253	flavin adenine dinucleotide binding
CH43_2850	COG1435	thymidine kinase activity
CH43_2851	COG1012	belongs to the aldehyde dehydrogenase family
CH43_2851	COG1454	alcohol dehydrogenase
CH43_2852	COG2095	MarC family integral membrane protein
CH43_2854	COG0601	transmembrane transport
CH43_2855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH43_2856	COG0444	Belongs to the ABC transporter superfamily
CH43_2857	COG4608	Belongs to the ABC transporter superfamily
CH43_2864	COG2350	Protein conserved in bacteria
CH43_2866	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH43_2867	COG3328	transposase activity
CH43_2868	COG1607	acyl-coa hydrolase
CH43_287	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH43_2873	COG3047	cAMP biosynthetic process
CH43_2877	COG0134	indole-3-glycerol-phosphate synthase activity
CH43_2877	COG0135	phosphoribosylanthranilate isomerase activity
CH43_2879	COG0512	Glutamine amidotransferase of anthranilate synthase
CH43_2882	COG0009	L-threonylcarbamoyladenylate synthase
CH43_2883	COG1187	pseudouridine synthase activity
CH43_2885	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_2886	COG0616	signal peptide processing
CH43_2889	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH43_289	COG0737	Belongs to the 5'-nucleotidase family
CH43_2890	COG1943	Transposase
CH43_2891	COG0583	DNA-binding transcription factor activity
CH43_2893	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH43_2894	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH43_2895	COG0671	phosphoesterase, PA-phosphatase related
CH43_2896	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH43_2897	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH43_29	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH43_2900	COG0023	Translation Initiation Factor
CH43_2904	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH43_2905	COG2879	small protein
CH43_2906	COG1966	Carbon starvation protein
CH43_2908	COG2271	Major facilitator Superfamily
CH43_2909	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH43_291	COG0545	Peptidyl-prolyl cis-trans isomerase
CH43_2910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH43_2912	COG4659	FMN binding
CH43_2913	COG4658	electron transport chain
CH43_2914	COG3708	Transcriptional regulator
CH43_2914	COG2207	Transcriptional regulator
CH43_292	COG3061	Opacity-associated protein A
CH43_2920	COG1132	(ABC) transporter
CH43_2922	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH43_2923	COG2274	protein secretion by the type I secretion system
CH43_2927	COG1879	ABC-type sugar transport system periplasmic component
CH43_2932	COG0673	inositol 2-dehydrogenase activity
CH43_2933	COG0385	Bile acid
CH43_2935	COG5339	Protein conserved in bacteria
CH43_2937	COG0114	fumarate hydratase activity
CH43_2939	COG2814	Major facilitator Superfamily
CH43_294	COG1943	Transposase
CH43_2940	COG0583	DNA-binding transcription factor activity
CH43_2941	COG1940	carbohydrate kinase activity
CH43_2943	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH43_2944	COG0038	chloride channel
CH43_2946	COG1609	Transcriptional regulator
CH43_2948	COG1879	ABC-type sugar transport system periplasmic component
CH43_2949	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH43_2950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH43_2952	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH43_2958	COG0028	Belongs to the TPP enzyme family
CH43_2959	COG0440	acetolactate synthase activity
CH43_296	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH43_2960	COG1011	Hydrolase
CH43_2963	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH43_2964	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH43_2965	COG0589	response to stress
CH43_2966	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH43_2967	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH43_2969	COG0531	amino acid
CH43_2971	COG0745	RESPONSE REGULATOR receiver
CH43_2972	COG2205	protein histidine kinase activity
CH43_2973	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH43_2978	COG3038	cytochrome b561
CH43_2980	COG3591	Belongs to the peptidase S1B family
CH43_2983	COG1643	Atp-dependent helicase
CH43_2985	COG2390	Transcriptional regulator
CH43_2986	COG0246	Mannitol dehydrogenase
CH43_2987	COG3784	Protein of unknown function (DUF1318)
CH43_2989	COG2911	Protein conserved in bacteria
CH43_299	COG1073	alpha beta
CH43_2990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH43_2991	COG3187	Heat shock protein
CH43_2992	COG3042	response to heat
CH43_2993	COG1285	pathogenesis
CH43_2995	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH43_2995	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH43_2995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH43_2995	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH43_2998	COG0657	acetylesterase activity
CH43_2998	COG2755	lipolytic protein G-D-S-L family
CH43_3	COG0656	L-ascorbic acid biosynthetic process
CH43_30	COG4181	ATPase activity
CH43_3001	COG4166	transmembrane transport
CH43_3002	COG2866	Carboxypeptidase
CH43_3003	COG4948	Mandelate Racemase Muconate Lactonizing
CH43_3004	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH43_3012	COG3106	COG3106 Predicted ATPase
CH43_3014	COG1983	PspC domain protein
CH43_3016	COG1842	Phage shock protein A
CH43_3017	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH43_3018	COG1943	Transposase
CH43_3019	COG4166	transmembrane transport
CH43_3020	COG4168	peptide transport system, permease
CH43_3021	COG4171	peptide transport system, permease
CH43_3023	COG4172	Belongs to the ABC transporter superfamily
CH43_3024	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH43_3024	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH43_3026	COG3104	oligopeptide transport
CH43_3029	COG0625	glutathione transferase activity
CH43_3033	COG3895	Periplasmic Protein
CH43_3035	COG3133	Outer membrane lipoprotein
CH43_3037	COG4989	oxidoreductase activity
CH43_3038	COG3313	Fe-S protein
CH43_3039	COG2194	sulfuric ester hydrolase activity
CH43_3040	COG1309	transcriptional regulator
CH43_3041	COG1902	pentaerythritol trinitrate reductase activity
CH43_3043	COG0346	lactoylglutathione lyase activity
CH43_3045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH43_3047	COG0791	NLP P60 protein
CH43_3048	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH43_305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH43_3051	COG0583	DNA-binding transcription factor activity
CH43_3052	COG2814	Major facilitator Superfamily
CH43_3053	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH43_3054	COG0307	riboflavin synthase, alpha
CH43_3059	COG4238	major outer membrane lipoprotein
CH43_3064	COG1388	LysM domain
CH43_3064	COG1376	ErfK ybiS ycfS ynhG family protein
CH43_3067	COG0719	Fe-S assembly protein
CH43_3068	COG0396	ATPase activity
CH43_3069	COG0719	Fe-S assembly protein
CH43_3070	COG0316	Belongs to the HesB IscA family
CH43_3071	COG2050	protein possibly involved in aromatic compounds catabolism
CH43_3072	COG0277	FAD linked oxidase domain protein
CH43_3072	COG0247	lactate metabolic process
CH43_3073	COG0628	permease
CH43_3074	COG0574	Belongs to the PEP-utilizing enzyme family
CH43_3074	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH43_3079	COG0791	NLP P60 protein
CH43_3087	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CH43_3088	COG0386	Belongs to the glutathione peroxidase family
CH43_3091	COG0776	regulation of translation
CH43_3092	COG0072	phenylalanine-tRNA ligase activity
CH43_3092	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH43_3093	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH43_3098	COG4249	Peptidase C14 caspase catalytic subunit p20
CH43_31	COG2755	lipolytic protein G-D-S-L family
CH43_3102	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH43_3103	COG1121	(ABC) transporter
CH43_3104	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH43_3105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH43_3108	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH43_3109	COG3328	transposase activity
CH43_311	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH43_3110	COG1917	Cupin 2, conserved barrel domain protein
CH43_3112	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_3114	COG1175	transmembrane transport
CH43_3115	COG0395	ABC-type sugar transport system, permease component
CH43_3116	COG3842	ATPase activity
CH43_3117	COG1653	transport
CH43_3118	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH43_3119	COG1988	membrane-bound metal-dependent
CH43_312	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH43_3121	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH43_3123	COG0823	Involved in the tonB-independent uptake of proteins
CH43_3124	COG2814	Major facilitator Superfamily
CH43_3125	COG3121	Chaperone
CH43_3128	COG3121	Chaperone
CH43_3129	COG3539	Fimbrial protein
CH43_313	COG1739	Uncharacterized protein family UPF0029
CH43_3132	COG0793	Belongs to the peptidase S41A family
CH43_3134	COG1956	GAF domain-containing protein
CH43_3135	COG2995	paraquat-inducible protein a
CH43_3136	COG3008	intermembrane lipid transfer
CH43_3140	COG3121	Chaperone
CH43_3153	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH43_3156	COG5295	Hep Hag repeat protein
CH43_3158	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH43_3159	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH43_3160	COG0745	RESPONSE REGULATOR receiver
CH43_3162	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH43_3163	COG0840	transmembrane signaling receptor activity
CH43_3164	COG0840	transmembrane signaling receptor activity
CH43_3168	COG2964	Protein conserved in bacteria
CH43_3170	COG0251	oxidation-reduction process
CH43_3171	COG2271	Major facilitator Superfamily
CH43_3172	COG0835	chemotaxis
CH43_3173	COG0643	Histidine kinase
CH43_3173	COG2198	Histidine kinase
CH43_3174	COG1360	Flagellar Motor Protein
CH43_3179	COG1285	pathogenesis
CH43_3180	COG0840	transmembrane signaling receptor activity
CH43_3181	COG0840	transmembrane signaling receptor activity
CH43_3183	COG1278	Cold shock
CH43_3185	COG0604	alcohol dehydrogenase
CH43_3185	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_3185	COG3321	synthase
CH43_3187	COG1522	sequence-specific DNA binding
CH43_3192	COG1733	regulation of RNA biosynthetic process
CH43_3193	COG0702	epimerase
CH43_3194	COG0840	transmembrane signaling receptor activity
CH43_3197	COG0538	isocitrate dehydrogenase activity
CH43_3198	COG1187	pseudouridine synthase activity
CH43_32	COG0300	oxidoreductase activity
CH43_3202	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH43_3204	COG0745	RESPONSE REGULATOR receiver
CH43_3206	COG2850	peptidyl-arginine hydroxylation
CH43_3208	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CH43_3210	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH43_3212	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH43_3213	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH43_3214	COG3134	Outer membrane lipoprotein
CH43_3215	COG3328	transposase activity
CH43_3218	COG1252	NADH dehydrogenase
CH43_322	COG0805	protein transport
CH43_3220	COG1472	Belongs to the glycosyl hydrolase 3 family
CH43_3223	COG5633	Lipoprotein
CH43_3224	COG0537	adenosine 5'-monophosphoramidase activity
CH43_3225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH43_3227	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH43_3227	COG1263	PTS System
CH43_3228	COG0084	hydrolase, TatD family'
CH43_3229	COG0470	DNA polymerase III
CH43_3231	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH43_3232	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH43_3233	COG1943	Transposase
CH43_3234	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH43_3236	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_324	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH43_3240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH43_3241	COG1399	metal-binding, possibly nucleic acid-binding protein
CH43_3243	COG0564	pseudouridine synthase activity
CH43_3244	COG1530	ribonuclease E activity
CH43_3245	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH43_3248	COG3328	transposase activity
CH43_3252	COG0628	permease
CH43_3256	COG2771	luxR family
CH43_3257	COG3916	Acyl-homoserine-lactone synthase
CH43_3258	COG0583	DNA-binding transcription factor activity
CH43_3260	COG0477	Major facilitator Superfamily
CH43_3262	COG0667	Aldo Keto reductase
CH43_3267	COG1203	CRISPR-associated helicase, Cas3
CH43_3268	COG1518	maintenance of DNA repeat elements
CH43_3269	COG0668	transmembrane transport
CH43_3273	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH43_3274	COG0395	ABC-type sugar transport system, permease component
CH43_3277	COG1609	Transcriptional regulator
CH43_3279	COG3842	ATPase activity
CH43_328	COG1322	Protein conserved in bacteria
CH43_3280	COG3328	transposase activity
CH43_3282	COG3210	domain, Protein
CH43_3286	COG3210	domain, Protein
CH43_3289	COG3210	domain, Protein
CH43_329	COG0586	Pfam SNARE associated Golgi protein
CH43_3290	COG2831	hemolysin activation secretion protein
CH43_3291	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH43_3292	COG4638	Rieske (2fe-2S)
CH43_3293	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH43_3294	COG0473	3-isopropylmalate dehydrogenase activity
CH43_3295	COG0583	DNA-binding transcription factor activity
CH43_3296	COG1609	Transcriptional regulator
CH43_3297	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_33	COG3118	belongs to the thioredoxin family
CH43_330	COG1966	Carbon starvation protein
CH43_3300	COG1879	ABC-type sugar transport system periplasmic component
CH43_3301	COG1063	alcohol dehydrogenase
CH43_3305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH43_3311	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH43_3312	COG0765	amino acid transport
CH43_3313	COG1126	abc transporter atp-binding protein
CH43_3317	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH43_332	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CH43_3320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH43_3323	COG1169	isochorismate synthase
CH43_3325	COG4575	ribosome binding
CH43_3327	COG0129	dihydroxy-acid dehydratase activity
CH43_333	COG0412	Dienelactone hydrolase
CH43_3330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH43_3331	COG1609	Transcriptional regulator
CH43_3333	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_3334	COG3265	gluconokinase activity
CH43_3335	COG2731	YhcH YjgK YiaL family protein
CH43_3338	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH43_3339	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH43_3341	COG0839	Belongs to the complex I subunit 6 family
CH43_3344	COG1034	ATP synthesis coupled electron transport
CH43_3346	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CH43_3348	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH43_3350	COG0583	DNA-binding transcription factor activity
CH43_3351	COG0436	Aminotransferase
CH43_3353	COG0490	domain, Protein
CH43_3353	COG0471	metal ion transport
CH43_3354	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH43_3358	COG0857	belongs to the CobB CobQ family
CH43_3358	COG0280	phosphate acetyltransferase
CH43_3359	COG1609	Transcriptional regulator
CH43_336	COG0583	DNA-binding transcription factor activity
CH43_3362	COG3037	sugar-specific permease SgaT UlaA
CH43_3363	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH43_3367	COG1090	epimerase
CH43_3368	COG4598	ABC transporter
CH43_3369	COG4160	amino acid transport
CH43_337	COG0679	Auxin Efflux Carrier
CH43_3370	COG4215	(ABC) transporter
CH43_3371	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH43_3372	COG0163	prenyltransferase activity
CH43_3373	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH43_3374	COG1286	toxin biosynthetic process
CH43_3375	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH43_3376	COG0285	dihydrofolate synthase activity
CH43_3378	COG0586	Pfam SNARE associated Golgi protein
CH43_338	COG0584	glycerophosphoryl diester phosphodiesterase
CH43_3380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH43_3383	COG0697	spore germination
CH43_3386	COG1794	racemase activity, acting on amino acids and derivatives
CH43_3387	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH43_3390	COG3101	peptidyl-lysine hydroxylation
CH43_3391	COG0730	response to heat
CH43_3394	COG2890	protein-(glutamine-N5) methyltransferase activity
CH43_3396	COG2062	phosphohistidine phosphatase, SixA
CH43_3399	COG3691	Protein conserved in bacteria
CH43_34	COG0330	HflC and HflK could
CH43_3402	COG3088	subunit of a heme lyase
CH43_3402	COG4235	cytochrome complex assembly
CH43_3403	COG4235	cytochrome complex assembly
CH43_3403	COG3088	subunit of a heme lyase
CH43_3404	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH43_3405	COG1138	Cytochrome C-type biogenesis protein
CH43_3407	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH43_3408	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH43_3409	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH43_3413	COG1704	LemA family
CH43_3415	COG2824	Alkylphosphonate utilization operon protein PhnA
CH43_3421	COG3501	Rhs element vgr protein
CH43_3434	COG3188	usher protein
CH43_3435	COG3328	transposase activity
CH43_3436	COG3188	usher protein
CH43_3437	COG3121	Chaperone
CH43_3449	COG2951	lytic endotransglycosylase activity
CH43_3456	COG0243	molybdopterin cofactor binding
CH43_3457	COG0437	4 iron, 4 sulfur cluster binding
CH43_3458	COG3302	dmso reductase anchor subunit
CH43_3459	COG3381	protein complex oligomerization
CH43_3465	COG3038	cytochrome b561
CH43_3466	COG0436	Aminotransferase
CH43_3471	COG0667	Aldo Keto reductase
CH43_3474	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH43_3481	COG1943	Transposase
CH43_3484	COG3530	Putative quorum-sensing-regulated virulence factor
CH43_3487	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH43_3488	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH43_3489	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_3491	COG2190	(PTS) system
CH43_3493	COG1943	Transposase
CH43_3495	COG2205	protein histidine kinase activity
CH43_3496	COG0745	RESPONSE REGULATOR receiver
CH43_3497	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH43_35	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH43_350	COG0410	ABC transporter
CH43_3500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH43_3502	COG0006	proline dipeptidase activity
CH43_3504	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH43_3506	COG5002	protein histidine kinase activity
CH43_3506	COG3850	Histidine kinase
CH43_3507	COG0745	RESPONSE REGULATOR receiver
CH43_351	COG0411	ABC transporter
CH43_3510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH43_3511	COG4208	sulfate ABC transporter
CH43_3512	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH43_3513	COG4150	thiosulfate binding
CH43_3515	COG1737	Transcriptional regulator
CH43_3516	COG2731	YhcH YjgK YiaL family protein
CH43_3518	COG4886	Leucine-rich repeat (LRR) protein
CH43_352	COG4177	L-phenylalanine transmembrane transporter activity
CH43_3520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH43_3521	COG2837	iron assimilation
CH43_3524	COG3111	PFAM Bacterial OB fold (BOF) protein
CH43_353	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH43_3533	COG3005	denitrification pathway
CH43_3534	COG3043	anaerobic respiration
CH43_3536	COG3062	negative regulation of establishment of protein localization
CH43_3537	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH43_3537	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH43_3538	COG2197	response regulator
CH43_354	COG0683	leucine binding
CH43_3540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH43_3542	COG1988	membrane-bound metal-dependent
CH43_3543	COG0641	radical SAM
CH43_3544	COG3119	arylsulfatase activity
CH43_3545	COG3842	ATPase activity
CH43_3546	COG1175	transmembrane transport
CH43_3547	COG1840	ABC-type Fe3 transport system, periplasmic component
CH43_3549	COG1393	Belongs to the ArsC family
CH43_3551	COG1876	peptidase activity
CH43_3555	COG2321	neutral zinc metallopeptidase
CH43_3557	COG1943	Transposase
CH43_3558	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH43_356	COG1943	Transposase
CH43_3560	COG2716	regulation of RNA biosynthetic process
CH43_3561	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH43_3564	COG0628	permease
CH43_3565	COG4783	chaperone-mediated protein folding
CH43_3566	COG1393	Belongs to the ArsC family
CH43_3568	COG1943	Transposase
CH43_3571	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH43_3572	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH43_3576	COG0581	inorganic phosphate transmembrane transporter activity
CH43_3578	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH43_3579	COG0248	Ppx GppA phosphatase
CH43_358	COG2177	Part of the ABC transporter FtsEX involved in
CH43_3580	COG2239	Acts as a magnesium transporter
CH43_3581	COG0443	Heat shock 70 kDa protein
CH43_3582	COG1177	transmembrane transport
CH43_3583	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH43_3585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH43_3587	COG3842	ATPase activity
CH43_359	COG2884	Cell division ATP-binding protein ftsE
CH43_3593	COG2205	protein histidine kinase activity
CH43_3594	COG0745	RESPONSE REGULATOR receiver
CH43_3595	COG3422	double-strand break repair
CH43_36	COG0789	Transcriptional regulator
CH43_360	COG0552	protein localization to endoplasmic reticulum
CH43_360	COG0552	protein localization to endoplasmic reticulum
CH43_3600	COG0351	phosphomethylpyrimidine kinase
CH43_3603	COG3328	transposase activity
CH43_361	COG0742	ribosomal rna small subunit methyltransferase
CH43_3610	COG1943	Transposase
CH43_3612	COG0516	GMP reductase activity
CH43_3612	COG0517	IMP dehydrogenase activity
CH43_3614	COG1645	bacterial-type flagellum-dependent swarming motility
CH43_3617	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH43_3618	COG2976	Protein conserved in bacteria
CH43_362	COG3776	membrane
CH43_3626	COG3468	outer membrane autotransporter barrel domain protein
CH43_3627	COG3468	outer membrane autotransporter barrel domain protein
CH43_3631	COG2975	iron-sulfur cluster assembly
CH43_3632	COG0633	Ferredoxin
CH43_3633	COG0443	Heat shock 70 kDa protein
CH43_3636	COG0822	iron-sulfur transferase activity
CH43_3637	COG1104	cysteine desulfurase activity
CH43_3640	COG0483	inositol monophosphate 1-phosphatase activity
CH43_3641	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH43_3642	COG3683	transport system, periplasmic component
CH43_3643	COG2814	Major facilitator Superfamily
CH43_3644	COG3711	transcriptional antiterminator
CH43_3647	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH43_3647	COG1017	nitric oxide dioxygenase activity
CH43_365	COG3714	YhhN family
CH43_3650	COG2188	Transcriptional regulator
CH43_3651	COG0347	Belongs to the P(II) protein family
CH43_3652	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH43_3652	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH43_3653	COG2204	response regulator
CH43_3654	COG3170	Tfp pilus assembly protein FimV
CH43_3655	COG2205	protein histidine kinase activity
CH43_3662	COG0590	tRNA wobble adenosine to inosine editing
CH43_3663	COG0560	Phosphoserine phosphatase
CH43_3665	COG1737	Transcriptional regulator
CH43_3666	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH43_3667	COG1943	Transposase
CH43_3668	COG3009	Protein conserved in bacteria
CH43_3669	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH43_3669	COG3008	intermembrane lipid transfer
CH43_3670	COG2995	paraquat-inducible protein a
CH43_3671	COG0488	(ABC) transporter
CH43_3673	COG3217	Mosc domain protein beta barrel domain protein
CH43_3673	COG0633	Ferredoxin
CH43_3676	COG0308	aminopeptidase N
CH43_368	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH43_3680	COG1448	Aminotransferase
CH43_3681	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH43_3682	COG3108	Peptidase M15
CH43_3683	COG2989	Protein conserved in bacteria
CH43_3686	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CH43_3687	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH43_3688	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH43_3689	COG3173	Aminoglycoside phosphotransferase
CH43_3691	COG2835	tetraacyldisaccharide 4'-kinase activity
CH43_3692	COG1278	Cold shock
CH43_3693	COG5383	Protein conserved in bacteria
CH43_3696	COG2333	competence protein COMEC
CH43_3696	COG0658	competence protein
CH43_3699	COG0539	negative regulation of cytoplasmic translation
CH43_37	COG2217	Heavy metal translocating P-type atpase
CH43_370	COG0247	lactate metabolic process
CH43_3704	COG5295	Hep Hag repeat protein
CH43_3704	COG5295	Hep Hag repeat protein
CH43_3705	COG0252	asparaginase activity
CH43_3706	COG1944	ATP diphosphatase activity
CH43_3707	COG2116	formate transmembrane transporter activity
CH43_3708	COG1882	Formate acetyltransferase
CH43_3710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH43_3711	COG2814	Major facilitator Superfamily
CH43_3713	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH43_3716	COG3107	peptidoglycan biosynthetic process
CH43_3716	COG1674	ftsk spoiiie
CH43_3718	COG0492	ferredoxin-NADP+ reductase activity
CH43_372	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH43_3720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH43_3722	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH43_3724	COG0542	response to heat
CH43_3726	COG1278	Cold shock
CH43_3728	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH43_3729	COG2990	Protein conserved in bacteria
CH43_373	COG0584	glycerophosphoryl diester phosphodiesterase
CH43_3730	COG3593	DNA synthesis involved in DNA repair
CH43_3731	COG2431	L-lysine efflux transmembrane transporter activity
CH43_3733	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH43_3734	COG0028	Belongs to the TPP enzyme family
CH43_3735	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH43_3736	COG0702	epimerase
CH43_3737	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH43_3739	COG1605	Chorismate mutase
CH43_3740	COG1126	abc transporter atp-binding protein
CH43_3741	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH43_3742	COG4215	(ABC) transporter
CH43_3743	COG4160	amino acid transport
CH43_3747	COG1120	ATPase activity
CH43_3748	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH43_375	COG0561	phosphatase activity
CH43_3755	COG1177	transmembrane transport
CH43_3756	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH43_3757	COG3842	ATPase activity
CH43_3758	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH43_376	COG2267	carboxylic ester hydrolase activity
CH43_3761	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH43_3762	COG2985	domain, Protein
CH43_3762	COG0569	domain protein
CH43_3764	COG0671	phosphoesterase, PA-phosphatase related
CH43_3765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH43_3766	COG1349	DNA-binding transcription factor activity
CH43_3767	COG0814	amino acid
CH43_3768	COG1686	Belongs to the peptidase S11 family
CH43_3769	COG2011	ABC-type metal ion transport system permease component
CH43_377	COG1280	lysine exporter protein (LysE YggA)
CH43_3774	COG0625	glutathione transferase activity
CH43_3775	COG4771	TonB-dependent receptor
CH43_3777	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH43_378	COG1280	lysine exporter protein (LysE YggA)
CH43_3780	COG0833	amino acid
CH43_3782	COG0583	DNA-binding transcription factor activity
CH43_3783	COG2855	membrane
CH43_3785	COG3188	usher protein
CH43_3786	COG3121	Chaperone
CH43_3789	COG3710	Transcriptional regulator
CH43_379	COG0514	ATP-dependent DNA helicase (RecQ)
CH43_3790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH43_3790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH43_3790	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH43_3791	COG1105	Belongs to the carbohydrate kinase PfkB family
CH43_3793	COG0494	nUDIX hydrolase
CH43_3794	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_3795	COG1129	ABC transporter
CH43_3797	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH43_38	COG3735	TraB family
CH43_380	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH43_3802	COG1028	Short-chain dehydrogenase reductase Sdr
CH43_3806	COG1312	Catalyzes the dehydration of D-mannonate
CH43_3807	COG0246	Mannitol dehydrogenase
CH43_3808	COG2186	Transcriptional regulator
CH43_381	COG2050	protein possibly involved in aromatic compounds catabolism
CH43_3810	COG0523	cobalamin synthesis protein
CH43_3811	COG0671	phosphoesterase, PA-phosphatase related
CH43_3812	COG0791	NLP P60 protein
CH43_3814	COG2200	EAL domain
CH43_3815	COG4166	transmembrane transport
CH43_3816	COG4174	ABC transporter (Permease)
CH43_3817	COG4239	(ABC) transporter, permease
CH43_3818	COG4172	Belongs to the ABC transporter superfamily
CH43_3820	COG2814	Major facilitator Superfamily
CH43_3821	COG1187	pseudouridine synthase activity
CH43_3822	COG1061	Type III restriction enzyme res subunit
CH43_3824	COG1943	Transposase
CH43_3826	COG3082	Protein of unknown function (DUF1414)
CH43_3827	COG3083	sulfuric ester hydrolase activity
CH43_383	COG0598	Magnesium transport protein CorA
CH43_3830	COG3157	Type VI secretion system effector, Hcp
CH43_3834	COG2723	6-phospho-beta-galactosidase activity
CH43_3836	COG1737	Transcriptional regulator
CH43_384	COG5564	TIM-barrel signal transduction protein
CH43_3840	COG3299	homolog of phage Mu protein gp47
CH43_3849	COG4386	tail sheath protein
CH43_385	COG5441	Belongs to the UPF0261 family
CH43_3853	COG3622	Belongs to the hyi family
CH43_3854	COG1349	DNA-binding transcription factor activity
CH43_3855	COG0235	Class ii aldolase
CH43_3856	COG3395	kinase activity
CH43_3865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH43_3868	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CH43_387	COG0210	DNA helicase
CH43_3872	COG0642	Histidine kinase
CH43_3872	COG2198	Histidine kinase
CH43_3873	COG0642	Histidine kinase
CH43_3873	COG2198	Histidine kinase
CH43_3875	COG0784	Response regulator, receiver
CH43_3875	COG2205	protein histidine kinase activity
CH43_388	COG1011	Hydrolase
CH43_3880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH43_3883	COG0814	amino acid
CH43_3888	COG0697	spore germination
CH43_389	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH43_3890	COG1982	Orn Lys Arg decarboxylase major
CH43_3891	COG3328	transposase activity
CH43_3892	COG1982	Orn Lys Arg decarboxylase major
CH43_3893	COG0531	amino acid
CH43_3894	COG1174	glycine betaine transport
CH43_3895	COG1125	glycine betaine transport
CH43_3896	COG1174	glycine betaine transport
CH43_3897	COG1732	Glycine betaine
CH43_3898	COG2897	thiosulfate sulfurtransferase activity
CH43_39	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH43_390	COG3159	Protein conserved in bacteria
CH43_3901	COG0410	ABC transporter
CH43_3902	COG1122	ATPase activity
CH43_3906	COG4807	Protein conserved in bacteria
CH43_3909	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH43_3911	COG2261	transglycosylase associated protein
CH43_3913	COG1403	HNH endonuclease
CH43_3915	COG0277	FAD linked oxidase domain protein
CH43_3916	COG1686	Belongs to the peptidase S11 family
CH43_3918	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH43_392	COG5567	small periplasmic lipoprotein
CH43_3921	COG2211	Major facilitator Superfamily
CH43_3922	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH43_3924	COG0583	DNA-binding transcription factor activity
CH43_3925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH43_3929	COG1943	Transposase
CH43_3930	COG0670	Belongs to the BI1 family
CH43_3931	COG0314	molybdopterin synthase activity
CH43_3932	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH43_3934	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH43_3936	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH43_3937	COG4628	conserved protein (DUF2132)
CH43_3938	COG0556	nucleotide-excision repair
CH43_394	COG3072	Adenylate cyclase
CH43_3940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH43_3941	COG2226	methyltransferase
CH43_3946	COG0561	phosphatase activity
CH43_3948	COG4149	molybdate abc transporter
CH43_3949	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH43_3951	COG3585	molybdate ion transport
CH43_3951	COG2005	Transcriptional regulator
CH43_3952	COG1119	ATPase activity
CH43_3956	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH43_3957	COG1085	galactose-1-phosphate uridylyltransferase
CH43_396	COG1587	Uroporphyrinogen-III synthase
CH43_3960	COG2017	converts alpha-aldose to the beta-anomer
CH43_3965	COG1230	cation diffusion facilitator family transporter
CH43_397	COG2959	enzyme of heme biosynthesis
CH43_3972	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH43_3973	COG2885	chlorophyll binding
CH43_3975	COG3064	Membrane
CH43_3975	COG3064	Membrane
CH43_3976	COG0848	biopolymer transport protein
CH43_3977	COG0811	peptide transport
CH43_3978	COG0824	Thioesterase
CH43_3979	COG3790	cyd operon protein YbgE
CH43_398	COG3071	HemY protein
CH43_3980	COG4890	Cyd operon protein YbgT
CH43_3981	COG1294	oxidase, subunit
CH43_3982	COG1271	oxidase subunit
CH43_3983	COG1943	Transposase
CH43_3984	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH43_3986	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH43_3987	COG0567	Dehydrogenase, E1 component
CH43_3989	COG1053	succinate dehydrogenase
CH43_3990	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH43_3991	COG2009	succinate dehydrogenase
CH43_3994	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH43_3995	COG0497	DNA recombination
CH43_3996	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH43_3998	COG2867	negative regulation of translational initiation
CH43_4	COG0667	Aldo Keto reductase
CH43_4001	COG0582	viral genome integration into host DNA
CH43_4011	COG3657	addiction module killer protein
CH43_4015	COG0582	viral genome integration into host DNA
CH43_4016	COG2963	transposase activity
CH43_4018	COG0596	Alpha beta hydrolase
CH43_4022	COG0735	belongs to the Fur family
CH43_4027	COG1263	PTS System
CH43_4027	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH43_4027	COG2190	(PTS) system
CH43_4029	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH43_4030	COG1846	Transcriptional regulator
CH43_4030	COG1940	carbohydrate kinase activity
CH43_4031	COG0647	UMP catabolic process
CH43_4032	COG0367	asparagine synthase
CH43_4039	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH43_4041	COG1702	phosphate starvation-inducible protein PhoH
CH43_4043	COG4535	Mg2 and Co2 transporter CorC
CH43_4044	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH43_4046	COG0765	amino acid transport
CH43_4047	COG0765	amino acid transport
CH43_4048	COG1126	abc transporter atp-binding protein
CH43_4049	COG2888	peptidyl-tyrosine sulfation
CH43_405	COG1113	amino acid transport
CH43_4052	COG1466	dna polymerase III delta subunit
CH43_4054	COG0799	negative regulation of ribosome biogenesis
CH43_4056	COG0768	penicillin binding
CH43_4057	COG0772	Belongs to the SEDS family
CH43_4058	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH43_4059	COG1686	Belongs to the peptidase S11 family
CH43_4063	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH43_4064	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH43_4065	COG1278	Cold shock
CH43_4066	COG1278	Cold shock
CH43_4067	COG2197	response regulator
CH43_4072	COG5265	(ABC) transporter
CH43_4074	COG3718	enzyme involved in inositol metabolism
CH43_4076	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH43_4077	COG0673	inositol 2-dehydrogenase activity
CH43_4078	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_4079	COG1129	ABC transporter
CH43_4080	COG1879	ABC-type sugar transport system periplasmic component
CH43_4081	COG0673	inositol 2-dehydrogenase activity
CH43_4082	COG0673	inositol 2-dehydrogenase activity
CH43_4083	COG3962	Belongs to the TPP enzyme family
CH43_4089	COG2373	Large extracellular alpha-helical protein
CH43_409	COG2244	polysaccharide biosynthetic process
CH43_4090	COG4953	penicillin-binding protein 1C
CH43_4091	COG3423	Transcriptional regulator
CH43_410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH43_4101	COG2850	peptidyl-arginine hydroxylation
CH43_4102	COG3328	transposase activity
CH43_411	COG0456	acetyltransferase
CH43_412	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH43_4120	COG1475	DNA binding
CH43_4123	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH43_4124	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH43_4124	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH43_413	COG1088	dTDP-glucose 4,6-dehydratase activity
CH43_4131	COG3941	tape measure
CH43_414	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH43_415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH43_4150	COG1475	DNA binding
CH43_4151	COG1475	DNA binding
CH43_4152	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH43_416	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH43_4163	COG1943	Transposase
CH43_4165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH43_4166	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH43_417	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH43_4172	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH43_418	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH43_4182	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH43_4184	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH43_419	COG3118	belongs to the thioredoxin family
CH43_42	COG0737	Belongs to the 5'-nucleotidase family
CH43_4209	COG3328	transposase activity
CH43_423	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH43_4232	COG3328	transposase activity
CH43_4237	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH43_4237	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CH43_4244	COG3177	Filamentation induced by cAMP protein fic
CH43_4249	COG4886	Leucine-rich repeat (LRR) protein
CH43_4251	COG3328	transposase activity
CH43_4254	COG0457	Tetratricopeptide repeat
CH43_4258	COG4789	Type iii secretion
CH43_426	COG3121	Chaperone
CH43_4267	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CH43_4268	COG4790	Type iii secretion
CH43_4269	COG4794	Type iii secretion
CH43_4270	COG4791	protein targeting
CH43_4271	COG4792	protein secretion
CH43_4273	COG2207	Transcriptional regulator
CH43_4282	COG4669	(LipO)protein
CH43_4284	COG1317	bacterial-type flagellum organization
CH43_4285	COG5599	Phosphatase
CH43_4286	COG2963	transposase activity
CH43_4287	COG2801	Transposase and inactivated derivatives
CH43_429	COG3121	Chaperone
CH43_4292	COG2801	Transposase and inactivated derivatives
CH43_4294	COG0515	serine threonine protein kinase
CH43_43	COG0737	Belongs to the 5'-nucleotidase family
CH43_4311	COG2801	Transposase and inactivated derivatives
CH43_4316	COG2801	Transposase and inactivated derivatives
CH43_4320	COG2801	Transposase and inactivated derivatives
CH43_4322	COG5599	Phosphatase
CH43_4324	COG3609	addiction module antidote protein, CC2985 family
CH43_4326	COG1475	DNA binding
CH43_4327	COG1192	Involved in chromosome partitioning
CH43_4329	COG2801	Transposase and inactivated derivatives
CH43_436	COG0583	DNA-binding transcription factor activity
CH43_44	COG0737	Belongs to the 5'-nucleotidase family
CH43_443	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH43_444	COG3978	acetolactate synthase activity
CH43_447	COG3085	chromosome segregation
CH43_448	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_450	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH43_451	COG1129	ABC transporter
CH43_452	COG1879	ABC-type sugar transport system periplasmic component
CH43_462	COG0151	Belongs to the GarS family
CH43_465	COG3068	Protein conserved in bacteria
CH43_466	COG1515	deoxyribonuclease V activity
CH43_47	COG4651	solute:proton antiporter activity
CH43_47	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH43_471	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH43_473	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH43_48	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH43_486	COG0250	Participates in transcription elongation, termination and antitermination
CH43_487	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH43_49	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH43_498	COG2986	histidine ammonia-lyase
CH43_501	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH43_504	COG4607	ABC-type enterochelin transport system periplasmic component
CH43_506	COG4605	iron ion homeostasis
CH43_508	COG4604	ABC transporter, ATP-binding protein
CH43_515	COG0582	viral genome integration into host DNA
CH43_517	COG2207	Transcriptional regulator
CH43_517	COG1609	Transcriptional regulator
CH43_518	COG4214	carbohydrate transport
CH43_520	COG4213	ABC transporter substrate-binding protein
CH43_522	COG1070	Carbohydrate kinase
CH43_524	COG3121	Chaperone
CH43_525	COG3188	usher protein
CH43_526	COG3188	usher protein
CH43_528	COG3274	enterobacterial common antigen metabolic process
CH43_53	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH43_530	COG2801	Transposase and inactivated derivatives
CH43_532	COG0527	aspartate kinase activity
CH43_532	COG0460	homoserine dehydrogenase
CH43_533	COG0626	cystathionine gamma-synthase activity
CH43_535	COG4682	membrane
CH43_537	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH43_539	COG1609	Transcriptional regulator
CH43_54	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH43_540	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH43_543	COG1575	Belongs to the MenA family. Type 1 subfamily
CH43_55	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH43_551	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH43_552	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH43_553	COG1494	fructose-1,6-bisphosphatase
CH43_555	COG3152	Membrane
CH43_558	COG0583	DNA-binding transcription factor activity
CH43_559	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH43_560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH43_564	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH43_569	COG3678	ATP-independent chaperone mediated protein folding
CH43_570	COG0745	RESPONSE REGULATOR receiver
CH43_571	COG2205	protein histidine kinase activity
CH43_572	COG2169	Transcriptional regulator
CH43_572	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH43_573	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH43_574	COG1045	serine acetyltransferase
CH43_577	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH43_578	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH43_580	COG4942	peptidase
CH43_581	COG2861	carbohydrate metabolic process
CH43_582	COG2861	carbohydrate metabolic process
CH43_584	COG0156	8-amino-7-oxononanoate synthase activity
CH43_586	COG0859	PFAM glycosyl transferase family 9
CH43_587	COG0859	PFAM glycosyl transferase family 9
CH43_588	COG1519	Transferase
CH43_592	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH43_595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH43_600	COG1561	YicC-like family, N-terminal region
CH43_601	COG2860	membrane
CH43_602	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH43_605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH43_606	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH43_607	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH43_608	COG0786	glutamate:sodium symporter activity
CH43_609	COG2233	PERMEase
CH43_610	COG2982	Protein involved in outer membrane biogenesis
CH43_611	COG0456	acetyltransferase
CH43_615	COG1295	ribonuclease BN
CH43_616	COG1011	Hydrolase
CH43_618	COG0174	glutamine synthetase
CH43_619	COG3852	Histidine kinase
CH43_621	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH43_624	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH43_624	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH43_625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH43_626	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH43_627	COG3084	Protein conserved in bacteria
CH43_629	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH43_63	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH43_630	COG3328	transposase activity
CH43_635	COG2186	Transcriptional regulator
CH43_637	COG0477	Major facilitator Superfamily
CH43_645	COG1522	sequence-specific DNA binding
CH43_646	COG0716	FMN binding
CH43_649	COG3312	ion transport
CH43_659	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH43_660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH43_661	COG0573	inorganic phosphate transmembrane transporter activity
CH43_662	COG0581	inorganic phosphate transmembrane transporter activity
CH43_664	COG0704	Plays a role in the regulation of phosphate uptake
CH43_666	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH43_667	COG0765	amino acid transport
CH43_668	COG0765	amino acid transport
CH43_669	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH43_67	COG0543	2 iron, 2 sulfur cluster binding
CH43_67	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH43_670	COG2252	PERMEase
CH43_675	COG0706	membrane insertase activity
CH43_678	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH43_681	COG0592	DNA-directed DNA polymerase activity
CH43_682	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH43_683	COG0187	DNA topoisomerase II activity
CH43_684	COG0561	phosphatase activity
CH43_685	COG2801	Transposase and inactivated derivatives
CH43_687	COG2423	ornithine cyclodeaminase activity
CH43_688	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH43_689	COG0823	Involved in the tonB-independent uptake of proteins
CH43_690	COG0823	Involved in the tonB-independent uptake of proteins
CH43_691	COG5645	(Lipo)protein
CH43_695	COG3977	Valine--pyruvate aminotransferase
CH43_697	COG0366	Alpha amylase catalytic
CH43_700	COG2885	chlorophyll binding
CH43_702	COG2818	Glycosylase
CH43_707	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH43_707	COG2213	PTS system mannitol-specific
CH43_709	COG3722	fumarate hydratase activity
CH43_716	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH43_718	COG3383	formate dehydrogenase (NAD+) activity
CH43_718	COG0243	molybdopterin cofactor binding
CH43_719	COG3383	formate dehydrogenase (NAD+) activity
CH43_719	COG0243	molybdopterin cofactor binding
CH43_720	COG0437	4 iron, 4 sulfur cluster binding
CH43_721	COG2864	formate dehydrogenase
CH43_724	COG3276	selenocysteine insertion sequence binding
CH43_726	COG3328	transposase activity
CH43_73	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH43_731	COG2801	Transposase and inactivated derivatives
CH43_733	COG1349	DNA-binding transcription factor activity
CH43_737	COG0058	SHG alpha-glucan phosphorylase activity
CH43_738	COG1640	4-alpha-glucanotransferase
CH43_745	COG1918	ferrous iron import across plasma membrane
CH43_746	COG2183	response to ionizing radiation
CH43_747	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH43_748	COG0745	RESPONSE REGULATOR receiver
CH43_75	COG2832	Protein of unknown function (DUF454)
CH43_752	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH43_753	COG1011	Hydrolase
CH43_756	COG0494	nUDIX hydrolase
CH43_757	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH43_762	COG4796	Type ii and iii secretion system protein
CH43_767	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH43_768	COG0546	phosphoglycolate phosphatase activity
CH43_769	COG0180	Tryptophanyl-tRNA synthetase
CH43_77	COG1196	nuclear chromosome segregation
CH43_77	COG3264	Mechanosensitive ion channel
CH43_772	COG2146	nitrite reductase [NAD(P)H] activity
CH43_773	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH43_774	COG0402	S-adenosylhomocysteine deaminase activity
CH43_778	COG1486	melibiose metabolic process
CH43_779	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH43_78	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH43_780	COG0433	COG0433 Predicted ATPase
CH43_783	COG1289	transmembrane transporter activity
CH43_785	COG1765	OsmC-like protein
CH43_787	COG3954	Phosphoribulokinase
CH43_789	COG0429	hydrolase of the alpha beta-hydrolase fold
CH43_79	COG1309	transcriptional regulator
CH43_791	COG4521	taurine ABC transporter
CH43_793	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH43_794	COG2175	clavaminate synthase activity
CH43_797	COG1216	Glycosyl transferase, family 2
CH43_798	COG0488	(ABC) transporter
CH43_80	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH43_801	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH43_802	COG1047	Peptidyl-prolyl cis-trans
CH43_804	COG0545	Peptidyl-prolyl cis-trans isomerase
CH43_805	COG2964	Protein conserved in bacteria
CH43_81	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH43_810	COG0049	tRNA binding
CH43_813	COG1943	Transposase
CH43_816	COG0051	transcription antitermination factor activity, RNA binding
CH43_821	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH43_823	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH43_824	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH43_826	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH43_827	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH43_83	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH43_835	COG1841	ribosomal large subunit assembly
CH43_837	COG0201	protein transport
CH43_838	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH43_841	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH43_844	COG0789	Transcriptional regulator
CH43_845	COG3036	rescue of stalled ribosome
CH43_847	COG0569	domain protein
CH43_851	COG0758	DNA mediated transformation
CH43_853	COG0551	DNA topoisomerase type I activity
CH43_856	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH43_863	COG2801	Transposase and inactivated derivatives
CH43_869	COG3162	membrane
CH43_87	COG3695	enzyme binding
CH43_871	COG1301	dicarboxylic acid transport
CH43_88	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH43_89	COG1946	Acyl-CoA thioesterase
CH43_893	COG2391	methyltransferase activity
CH43_894	COG0425	Belongs to the sulfur carrier protein TusA family
CH43_895	COG0583	DNA-binding transcription factor activity
CH43_896	COG0814	amino acid
CH43_897	COG0626	cystathionine gamma-synthase activity
CH43_899	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH43_90	COG0004	ammonium transporteR
CH43_900	COG4558	Periplasmic binding protein
CH43_901	COG3720	iron ion transport
CH43_902	COG4771	TonB-dependent receptor
CH43_904	COG0702	epimerase
CH43_905	COG3721	Heme iron utilization protein
CH43_91	COG0347	Belongs to the P(II) protein family
CH43_910	COG1358	cellular component organization or biogenesis
CH43_92	COG1132	(ABC) transporter
CH43_922	COG3121	Chaperone
CH43_93	COG1132	(ABC) transporter
CH43_931	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH43_933	COG0735	belongs to the Fur family
CH43_934	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH43_937	COG0305	Participates in initiation and elongation during chromosome replication
CH43_938	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH43_939	COG1448	Aminotransferase
CH43_94	COG1522	sequence-specific DNA binding
CH43_940	COG2315	Protein conserved in bacteria
CH43_941	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH43_942	COG0629	single-stranded DNA binding
CH43_944	COG1454	alcohol dehydrogenase
CH43_958	COG1309	transcriptional regulator
CH43_959	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH43_959	COG0493	'glutamate synthase
CH43_960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH43_961	COG3383	formate dehydrogenase (NAD+) activity
CH43_964	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH43_97	COG4533	DNA binding
CH43_972	COG2076	Multidrug Resistance protein
CH43_973	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH43_975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH43_976	COG1053	succinate dehydrogenase
CH43_978	COG1511	domain protein
CH43_978	COG3264	Mechanosensitive ion channel
CH43_981	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH43_984	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH43_985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH43_985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH43_986	COG0802	atpase or kinase
CH43_987	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH43_99	COG0824	Thioesterase
CH43_991	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH43_992	COG0330	HflC and HflK could
CH43_993	COG0330	HflC and HflK could
CH43_994	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH43_997	COG0557	exoribonuclease II activity
CH43_998	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH43_999	COG1960	acyl-CoA dehydrogenase activity