locus-tag	class	description
GCK68_00010	COG0592	DNA-directed DNA polymerase activity
GCK68_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GCK68_00020	COG0187	DNA topoisomerase II activity
GCK68_00025	COG0561	phosphatase activity
GCK68_00040	COG2423	ornithine cyclodeaminase activity
GCK68_00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCK68_00060	COG5645	(Lipo)protein
GCK68_00080	COG3977	Valine--pyruvate aminotransferase
GCK68_00100	COG0366	Alpha amylase catalytic
GCK68_00120	COG2885	chlorophyll binding
GCK68_00130	COG2818	Glycosylase
GCK68_00155	COG2213	PTS system mannitol-specific
GCK68_00155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_00165	COG3722	fumarate hydratase activity
GCK68_00190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK68_00205	COG0437	4 iron, 4 sulfur cluster binding
GCK68_00210	COG2864	formate dehydrogenase
GCK68_00225	COG3276	selenocysteine insertion sequence binding
GCK68_00270	COG3274	enterobacterial common antigen metabolic process
GCK68_00285	COG3121	Chaperone
GCK68_00295	COG1070	Carbohydrate kinase
GCK68_00305	COG4213	ABC transporter substrate-binding protein
GCK68_00315	COG4214	carbohydrate transport
GCK68_00320	COG1609	Transcriptional regulator
GCK68_00320	COG2207	Transcriptional regulator
GCK68_00330	COG0582	viral genome integration into host DNA
GCK68_00380	COG4604	ABC transporter, ATP-binding protein
GCK68_00385	COG4605	iron ion homeostasis
GCK68_00395	COG4607	ABC-type enterochelin transport system periplasmic component
GCK68_00410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GCK68_00425	COG2986	histidine ammonia-lyase
GCK68_00440	COG2194	sulfuric ester hydrolase activity
GCK68_00445	COG2197	response regulator
GCK68_00465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCK68_00480	COG0551	DNA topoisomerase type I activity
GCK68_00490	COG0758	DNA mediated transformation
GCK68_00510	COG0569	domain protein
GCK68_00520	COG3036	rescue of stalled ribosome
GCK68_00525	COG0789	Transcriptional regulator
GCK68_00540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GCK68_00555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK68_00560	COG0201	protein transport
GCK68_00570	COG1841	ribosomal large subunit assembly
GCK68_00610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GCK68_00615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GCK68_00625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCK68_00630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GCK68_00640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GCK68_00665	COG0051	transcription antitermination factor activity, RNA binding
GCK68_00685	COG1943	Transposase
GCK68_00700	COG0049	tRNA binding
GCK68_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GCK68_00725	COG2964	Protein conserved in bacteria
GCK68_00730	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK68_00745	COG1047	Peptidyl-prolyl cis-trans
GCK68_00750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GCK68_00760	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK68_00770	COG1216	Glycosyl transferase, family 2
GCK68_00780	COG2175	clavaminate synthase activity
GCK68_00785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK68_00795	COG4521	taurine ABC transporter
GCK68_00805	COG0429	hydrolase of the alpha beta-hydrolase fold
GCK68_00815	COG3954	Phosphoribulokinase
GCK68_00825	COG1765	OsmC-like protein
GCK68_00835	COG1289	transmembrane transporter activity
GCK68_00850	COG0433	COG0433 Predicted ATPase
GCK68_00855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK68_00860	COG1486	melibiose metabolic process
GCK68_00880	COG0402	S-adenosylhomocysteine deaminase activity
GCK68_00885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCK68_00890	COG2146	nitrite reductase [NAD(P)H] activity
GCK68_00905	COG0180	Tryptophanyl-tRNA synthetase
GCK68_00910	COG0546	phosphoglycolate phosphatase activity
GCK68_00915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCK68_00940	COG4796	Type ii and iii secretion system protein
GCK68_00970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GCK68_00975	COG0494	nUDIX hydrolase
GCK68_00985	COG1011	Hydrolase
GCK68_00990	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GCK68_01010	COG0745	RESPONSE REGULATOR receiver
GCK68_01015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK68_01020	COG2183	response to ionizing radiation
GCK68_01025	COG1918	ferrous iron import across plasma membrane
GCK68_01060	COG1640	4-alpha-glucanotransferase
GCK68_01065	COG0058	SHG alpha-glucan phosphorylase activity
GCK68_01070	COG0058	SHG alpha-glucan phosphorylase activity
GCK68_01090	COG1349	DNA-binding transcription factor activity
GCK68_01125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK68_01130	COG0058	SHG alpha-glucan phosphorylase activity
GCK68_01155	COG3275	phosphorelay sensor kinase activity
GCK68_01185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK68_01190	COG2095	MarC family integral membrane protein
GCK68_01210	COG3265	gluconokinase activity
GCK68_01215	COG2610	gluconate transmembrane transporter activity
GCK68_01220	COG1609	Transcriptional regulator
GCK68_01225	COG1741	Belongs to the pirin family
GCK68_01240	COG0745	RESPONSE REGULATOR receiver
GCK68_01250	COG0191	fructose-bisphosphate aldolase activity
GCK68_01260	COG1879	ABC-type sugar transport system periplasmic component
GCK68_01265	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_01280	COG2081	HI0933 family
GCK68_01285	COG0306	phosphate transporter
GCK68_01290	COG1943	Transposase
GCK68_01300	COG0589	response to stress
GCK68_01320	COG0339	signal peptide processing
GCK68_01325	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GCK68_01330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK68_01335	COG3835	regulator
GCK68_01345	COG2610	gluconate transmembrane transporter activity
GCK68_01350	COG1929	Belongs to the glycerate kinase type-1 family
GCK68_01375	COG1295	ribonuclease BN
GCK68_01380	COG2134	cdp-diacylglycerol pyrophosphatase
GCK68_01385	COG2982	Protein involved in outer membrane biogenesis
GCK68_01390	COG2200	EAL domain
GCK68_01395	COG1942	4-Oxalocrotonate Tautomerase
GCK68_01400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK68_01405	COG0612	Peptidase, M16
GCK68_01425	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK68_01430	COG2199	diguanylate cyclase activity
GCK68_01430	COG2200	EAL domain
GCK68_01435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK68_01440	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK68_01445	COG4608	Belongs to the ABC transporter superfamily
GCK68_01450	COG0444	Belongs to the ABC transporter superfamily
GCK68_01455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK68_01460	COG0601	transmembrane transport
GCK68_01465	COG0747	negative chemotaxis
GCK68_01475	COG2831	hemolysin activation secretion protein
GCK68_01490	COG2271	Major facilitator Superfamily
GCK68_01540	COG3328	transposase activity
GCK68_01545	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCK68_01555	COG3084	Protein conserved in bacteria
GCK68_01560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCK68_01565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK68_01570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK68_01570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK68_01575	COG1943	Transposase
GCK68_01580	COG1943	Transposase
GCK68_01605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK68_01615	COG3852	Histidine kinase
GCK68_01620	COG0174	glutamine synthetase
GCK68_01630	COG1011	Hydrolase
GCK68_01635	COG1295	ribonuclease BN
GCK68_01655	COG1401	restriction endodeoxyribonuclease activity
GCK68_01715	COG4269	membrane
GCK68_01725	COG2207	Transcriptional regulator
GCK68_01730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK68_01735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK68_01740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK68_01745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK68_01745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_01745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_01800	COG0859	PFAM glycosyl transferase family 9
GCK68_01815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK68_01820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK68_01845	COG3706	GGDEF domain
GCK68_01865	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GCK68_01870	COG0456	acetyltransferase
GCK68_01880	COG2823	Periplasmic or secreted lipoprotein
GCK68_01890	COG4667	esterase of the alpha-beta hydrolase superfamily
GCK68_01895	COG0084	hydrolase, TatD family'
GCK68_01900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK68_01905	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK68_01925	COG3726	membrane protein affecting hemolysin expression
GCK68_01930	COG0560	Phosphoserine phosphatase
GCK68_01955	COG2885	chlorophyll binding
GCK68_01960	COG2199	diguanylate cyclase activity
GCK68_01975	COG0741	lytic transglycosylase activity
GCK68_01980	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GCK68_01995	COG3708	Transcriptional regulator
GCK68_01995	COG2207	Transcriptional regulator
GCK68_02005	COG3045	CreA protein
GCK68_02010	COG0745	RESPONSE REGULATOR receiver
GCK68_02050	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCK68_02065	COG1584	GPR1 FUN34 yaaH family protein
GCK68_02085	COG0583	DNA-binding transcription factor activity
GCK68_02105	COG0196	riboflavin kinase activity
GCK68_02120	COG1047	Peptidyl-prolyl cis-trans
GCK68_02130	COG1943	Transposase
GCK68_02140	COG0473	3-isopropylmalate dehydrogenase activity
GCK68_02155	COG2814	Major facilitator Superfamily
GCK68_02170	COG4143	(ABC) transporter
GCK68_02175	COG1178	ABC-type Fe3 transport system permease component
GCK68_02185	COG0586	Pfam SNARE associated Golgi protein
GCK68_02190	COG0417	DNA replication proofreading
GCK68_02210	COG3047	cAMP biosynthetic process
GCK68_02210	COG2885	chlorophyll binding
GCK68_02245	COG3501	Rhs element vgr protein
GCK68_02295	COG0564	pseudouridine synthase activity
GCK68_02300	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GCK68_02310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK68_02315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GCK68_02345	COG1943	Transposase
GCK68_02350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCK68_02360	COG2966	Psort location CytoplasmicMembrane, score
GCK68_02365	COG1280	lysine exporter protein (LysE YggA)
GCK68_02370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GCK68_02375	COG0505	Belongs to the CarA family
GCK68_02385	COG1943	Transposase
GCK68_02405	COG1022	Amp-dependent synthetase and ligase
GCK68_02415	COG0028	Belongs to the TPP enzyme family
GCK68_02425	COG1943	Transposase
GCK68_02435	COG1609	Transcriptional regulator
GCK68_02460	COG3116	cell division
GCK68_02465	COG0768	penicillin binding
GCK68_02470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCK68_02475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GCK68_02490	COG0772	Belongs to the SEDS family
GCK68_02510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GCK68_02515	COG0849	cell division
GCK68_02520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCK68_02550	COG0494	nUDIX hydrolase
GCK68_02570	COG2259	Doxx family
GCK68_02580	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GCK68_02585	COG4575	ribosome binding
GCK68_02605	COG0586	Pfam SNARE associated Golgi protein
GCK68_02620	COG2271	Major facilitator Superfamily
GCK68_02630	COG0246	Mannitol dehydrogenase
GCK68_02635	COG2721	sulfolactate sulfo-lyase activity
GCK68_02645	COG1943	Transposase
GCK68_02655	COG0673	inositol 2-dehydrogenase activity
GCK68_02660	COG1451	nucleotide metabolic process
GCK68_02675	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCK68_02675	COG1902	pentaerythritol trinitrate reductase activity
GCK68_02680	COG3247	response to pH
GCK68_02700	COG4245	von Willebrand factor, type A
GCK68_02715	COG4245	von Willebrand factor, type A
GCK68_02720	COG2831	hemolysin activation secretion protein
GCK68_02725	COG3210	domain, Protein
GCK68_02750	COG3210	domain, Protein
GCK68_02755	COG3210	domain, Protein
GCK68_02775	COG3842	ATPase activity
GCK68_02780	COG3459	Glycosyltransferase 36 associated
GCK68_02785	COG1609	Transcriptional regulator
GCK68_02790	COG1653	transport
GCK68_02800	COG0395	ABC-type sugar transport system, permease component
GCK68_02820	COG1289	transmembrane transporter activity
GCK68_02865	COG0251	oxidation-reduction process
GCK68_02935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCK68_02940	COG0358	DNA primase activity
GCK68_02965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GCK68_02980	COG4991	sh3 domain protein
GCK68_02985	COG3025	triphosphatase activity
GCK68_03000	COG0531	amino acid
GCK68_03020	COG3384	dioxygenase
GCK68_03025	COG0754	glutathionylspermidine amidase activity
GCK68_03040	COG1538	Outer membrane efflux protein
GCK68_03045	COG0494	nUDIX hydrolase
GCK68_03050	COG3151	Protein conserved in bacteria
GCK68_03055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCK68_03060	COG3150	esterase
GCK68_03065	COG0187	DNA topoisomerase II activity
GCK68_03070	COG0583	DNA-binding transcription factor activity
GCK68_03075	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK68_03085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GCK68_03090	COG0204	Acyl-transferase
GCK68_03100	COG2132	Multicopper oxidase
GCK68_03115	COG0656	L-ascorbic acid biosynthetic process
GCK68_03125	COG1979	alcohol dehydrogenase
GCK68_03130	COG2207	Transcriptional regulator
GCK68_03135	COG0586	Pfam SNARE associated Golgi protein
GCK68_03140	COG0626	cystathionine gamma-synthase activity
GCK68_03145	COG0811	peptide transport
GCK68_03150	COG0848	biopolymer transport protein
GCK68_03205	COG4964	Belongs to the GSP D family
GCK68_03210	COG4964	Belongs to the GSP D family
GCK68_03225	COG1943	Transposase
GCK68_03245	COG4592	Periplasmic binding protein
GCK68_03270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK68_03275	COG1684	flagellar biosynthetic protein fliR
GCK68_03280	COG1987	bacterial-type flagellum assembly
GCK68_03300	COG2204	response regulator
GCK68_03345	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GCK68_03350	COG1815	bacterial-type flagellum-dependent cell motility
GCK68_03355	COG1558	bacterial-type flagellum-dependent cell motility
GCK68_03360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK68_03365	COG1749	Flagellar hook protein flgE
GCK68_03370	COG4787	bacterial-type flagellum-dependent cell motility
GCK68_03375	COG4786	Flagellar basal body rod
GCK68_03380	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GCK68_03385	COG1706	bacterial-type flagellum-dependent cell motility
GCK68_03395	COG1256	bacterial-type flagellum assembly
GCK68_03415	COG3710	Transcriptional regulator
GCK68_03440	COG0471	metal ion transport
GCK68_03460	COG3209	COG3209 Rhs family protein
GCK68_03470	COG3501	Rhs element vgr protein
GCK68_03485	COG2610	gluconate transmembrane transporter activity
GCK68_03500	COG1132	(ABC) transporter
GCK68_03535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK68_03540	COG3433	isochorismatase activity
GCK68_03540	COG2226	methyltransferase
GCK68_03540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK68_03555	COG1943	Transposase
GCK68_03560	COG3119	arylsulfatase activity
GCK68_03565	COG1349	DNA-binding transcription factor activity
GCK68_03575	COG2222	sugar isomerase
GCK68_03580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK68_03585	COG3715	PTS system
GCK68_03590	COG3716	PTS system mannose fructose sorbose family IID component
GCK68_03595	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_03605	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_03615	COG0641	radical SAM
GCK68_03620	COG3119	arylsulfatase activity
GCK68_03630	COG0191	fructose-bisphosphate aldolase activity
GCK68_03650	COG2271	Major facilitator Superfamily
GCK68_03670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK68_03670	COG1263	PTS System
GCK68_03675	COG1874	Beta-galactosidase
GCK68_03680	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GCK68_03685	COG3833	ABC-type maltose transport systems, permease component
GCK68_03690	COG1175	transmembrane transport
GCK68_03695	COG2182	Extracellular solute-binding protein
GCK68_03705	COG1129	ABC transporter
GCK68_03710	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_03715	COG1879	ABC-type sugar transport system periplasmic component
GCK68_03725	COG0791	NLP P60 protein
GCK68_03730	COG1695	Transcriptional regulator
GCK68_03820	COG2944	sequence-specific DNA binding
GCK68_03845	COG0582	viral genome integration into host DNA
GCK68_03865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GCK68_03870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK68_03875	COG4974	Belongs to the 'phage' integrase family
GCK68_03880	COG0716	FMN binding
GCK68_03885	COG4452	Inner membrane protein CreD
GCK68_03890	COG2205	protein histidine kinase activity
GCK68_03895	COG0745	RESPONSE REGULATOR receiver
GCK68_03905	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GCK68_03920	COG1272	protein, Hemolysin III
GCK68_03965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK68_03970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK68_03975	COG0006	proline dipeptidase activity
GCK68_03995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCK68_04000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCK68_04005	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCK68_04035	COG0191	fructose-bisphosphate aldolase activity
GCK68_04050	COG1943	Transposase
GCK68_04055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCK68_04060	COG0501	Belongs to the peptidase M48B family
GCK68_04075	COG1166	arginine decarboxylase activity
GCK68_04090	COG2356	endonuclease I
GCK68_04095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCK68_04100	COG0189	ligase activity
GCK68_04115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK68_04125	COG2805	Type II/IV secretion system protein
GCK68_04130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCK68_04135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCK68_04145	COG0762	integral membrane protein
GCK68_04155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GCK68_04160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK68_04165	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GCK68_04165	COG1073	alpha beta
GCK68_04165	COG3064	Membrane
GCK68_04175	COG2066	Belongs to the glutaminase family
GCK68_04180	COG3171	Protein conserved in bacteria
GCK68_04190	COG1194	a g-specific adenine glycosylase
GCK68_04210	COG4774	siderophore transport
GCK68_04215	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_04220	COG1129	ABC transporter
GCK68_04225	COG1879	ABC-type sugar transport system periplasmic component
GCK68_04230	COG1982	Orn Lys Arg decarboxylase major
GCK68_04360	COG3916	Acyl-homoserine-lactone synthase
GCK68_04365	COG2771	luxR family
GCK68_04415	COG2211	Major facilitator Superfamily
GCK68_04425	COG3300	MHYT domain
GCK68_04425	COG5001	Diguanylate cyclase
GCK68_04435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK68_04490	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GCK68_04495	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK68_04500	COG4771	TonB-dependent receptor
GCK68_04545	COG0288	reversible hydration of carbon dioxide
GCK68_04595	COG2165	general secretion pathway protein
GCK68_04640	COG0840	transmembrane signaling receptor activity
GCK68_04655	COG0583	DNA-binding transcription factor activity
GCK68_04660	COG2814	Major facilitator Superfamily
GCK68_04665	COG0583	DNA-binding transcription factor activity
GCK68_04670	COG0019	diaminopimelate decarboxylase activity
GCK68_04675	COG1609	Transcriptional regulator
GCK68_04705	COG0667	Aldo Keto reductase
GCK68_04770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GCK68_04780	COG1074	ATP-dependent DNA helicase activity
GCK68_04785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GCK68_04795	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK68_04810	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GCK68_04815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCK68_04820	COG2166	iron-sulfur cluster assembly
GCK68_04825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCK68_04835	COG0583	DNA-binding transcription factor activity
GCK68_04840	COG2363	Small membrane protein
GCK68_04850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK68_04870	COG1611	Belongs to the LOG family
GCK68_04885	COG1943	Transposase
GCK68_04890	COG3098	single-species biofilm formation
GCK68_04895	COG0564	pseudouridine synthase activity
GCK68_04920	COG0024	Methionine aminopeptidase
GCK68_04955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GCK68_04960	COG0575	Belongs to the CDS family
GCK68_04965	COG0750	zinc metalloprotease
GCK68_04975	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GCK68_04995	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCK68_05005	COG0587	DNA-directed DNA polymerase activity
GCK68_05015	COG0346	lactoylglutathione lyase activity
GCK68_05020	COG0037	tRNA processing
GCK68_05030	COG4568	rho-dependent transcription termination
GCK68_05040	COG4681	YaeQ
GCK68_05050	COG3015	lipoprotein NlpE involved in copper resistance
GCK68_05060	COG1720	tRNA m6t6A37 methyltransferase activity
GCK68_05070	COG1464	Belongs to the NlpA lipoprotein family
GCK68_05075	COG2011	ABC-type metal ion transport system permease component
GCK68_05085	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK68_05120	COG0656	L-ascorbic acid biosynthetic process
GCK68_05135	COG1388	LysM domain
GCK68_05135	COG0741	lytic transglycosylase activity
GCK68_05145	COG2226	methyltransferase
GCK68_05155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK68_05165	COG1953	Uracil, thiamine, allantoin
GCK68_05190	COG3657	addiction module killer protein
GCK68_05250	COG0582	viral genome integration into host DNA
GCK68_05260	COG1943	Transposase
GCK68_05275	COG2867	negative regulation of translational initiation
GCK68_05285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK68_05290	COG0497	DNA recombination
GCK68_05295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GCK68_05310	COG2009	succinate dehydrogenase
GCK68_05315	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GCK68_05320	COG1053	succinate dehydrogenase
GCK68_05330	COG0567	Dehydrogenase, E1 component
GCK68_05335	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK68_05345	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCK68_05350	COG1271	oxidase subunit
GCK68_05355	COG1294	oxidase, subunit
GCK68_05360	COG4890	Cyd operon protein YbgT
GCK68_05365	COG3790	cyd operon protein YbgE
GCK68_05370	COG0824	Thioesterase
GCK68_05375	COG0811	peptide transport
GCK68_05380	COG0848	biopolymer transport protein
GCK68_05385	COG3064	Membrane
GCK68_05385	COG3064	Membrane
GCK68_05395	COG2885	chlorophyll binding
GCK68_05400	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GCK68_05430	COG1230	cation diffusion facilitator family transporter
GCK68_05435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK68_05450	COG2017	converts alpha-aldose to the beta-anomer
GCK68_05465	COG1085	galactose-1-phosphate uridylyltransferase
GCK68_05470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCK68_05480	COG1119	ATPase activity
GCK68_05490	COG2005	Transcriptional regulator
GCK68_05490	COG3585	molybdate ion transport
GCK68_05500	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCK68_05505	COG4149	molybdate abc transporter
GCK68_05515	COG0561	phosphatase activity
GCK68_05540	COG2226	methyltransferase
GCK68_05545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK68_05555	COG0556	nucleotide-excision repair
GCK68_05560	COG4628	conserved protein (DUF2132)
GCK68_05565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GCK68_05570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GCK68_05580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GCK68_05585	COG0314	molybdopterin synthase activity
GCK68_05590	COG0670	Belongs to the BI1 family
GCK68_05595	COG1943	Transposase
GCK68_05605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK68_05615	COG1686	Belongs to the peptidase S11 family
GCK68_05620	COG0277	FAD linked oxidase domain protein
GCK68_05630	COG1403	HNH endonuclease
GCK68_05640	COG2261	transglycosylase associated protein
GCK68_05650	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GCK68_05665	COG4807	Protein conserved in bacteria
GCK68_05685	COG1122	ATPase activity
GCK68_05690	COG0410	ABC transporter
GCK68_05705	COG2897	thiosulfate sulfurtransferase activity
GCK68_05710	COG1732	Glycine betaine
GCK68_05715	COG1732	Glycine betaine
GCK68_05720	COG1174	glycine betaine transport
GCK68_05725	COG1125	glycine betaine transport
GCK68_05730	COG1174	glycine betaine transport
GCK68_05735	COG0531	amino acid
GCK68_05740	COG1982	Orn Lys Arg decarboxylase major
GCK68_05750	COG0697	spore germination
GCK68_05775	COG0814	amino acid
GCK68_05790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK68_05815	COG0784	Response regulator, receiver
GCK68_05815	COG2205	protein histidine kinase activity
GCK68_05825	COG0642	Histidine kinase
GCK68_05825	COG2198	Histidine kinase
GCK68_05830	COG2198	Histidine kinase
GCK68_05830	COG0642	Histidine kinase
GCK68_05835	COG2223	nitrite transmembrane transporter activity
GCK68_05840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCK68_05845	COG1943	Transposase
GCK68_05865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCK68_05910	COG3395	kinase activity
GCK68_05915	COG0235	Class ii aldolase
GCK68_05920	COG1349	DNA-binding transcription factor activity
GCK68_05925	COG3622	Belongs to the hyi family
GCK68_05945	COG4386	tail sheath protein
GCK68_05985	COG3299	homolog of phage Mu protein gp47
GCK68_06005	COG1737	Transcriptional regulator
GCK68_06010	COG2723	6-phospho-beta-galactosidase activity
GCK68_06025	COG3157	Type VI secretion system effector, Hcp
GCK68_06045	COG3083	sulfuric ester hydrolase activity
GCK68_06050	COG3082	Protein of unknown function (DUF1414)
GCK68_06060	COG1943	Transposase
GCK68_06075	COG1061	Type III restriction enzyme res subunit
GCK68_06080	COG1187	pseudouridine synthase activity
GCK68_06085	COG2814	Major facilitator Superfamily
GCK68_06095	COG4172	Belongs to the ABC transporter superfamily
GCK68_06100	COG4239	(ABC) transporter, permease
GCK68_06105	COG4174	ABC transporter (Permease)
GCK68_06110	COG4166	transmembrane transport
GCK68_06115	COG2200	EAL domain
GCK68_06120	COG0791	NLP P60 protein
GCK68_06125	COG0671	phosphoesterase, PA-phosphatase related
GCK68_06130	COG0523	cobalamin synthesis protein
GCK68_06140	COG2186	Transcriptional regulator
GCK68_06145	COG0246	Mannitol dehydrogenase
GCK68_06150	COG1312	Catalyzes the dehydration of D-mannonate
GCK68_06170	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_06195	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCK68_06205	COG1129	ABC transporter
GCK68_06210	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_06215	COG0494	nUDIX hydrolase
GCK68_06225	COG1105	Belongs to the carbohydrate kinase PfkB family
GCK68_06230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GCK68_06230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK68_06230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK68_06235	COG3710	Transcriptional regulator
GCK68_06250	COG3121	Chaperone
GCK68_06255	COG3188	usher protein
GCK68_06265	COG2855	membrane
GCK68_06270	COG0583	DNA-binding transcription factor activity
GCK68_06275	COG0833	amino acid
GCK68_06285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK68_06295	COG4771	TonB-dependent receptor
GCK68_06305	COG0625	glutathione transferase activity
GCK68_06330	COG2011	ABC-type metal ion transport system permease component
GCK68_06335	COG1686	Belongs to the peptidase S11 family
GCK68_06340	COG0814	amino acid
GCK68_06345	COG1349	DNA-binding transcription factor activity
GCK68_06350	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK68_06355	COG0671	phosphoesterase, PA-phosphatase related
GCK68_06365	COG0569	domain protein
GCK68_06365	COG2985	domain, Protein
GCK68_06370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK68_06390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCK68_06395	COG3842	ATPase activity
GCK68_06400	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK68_06405	COG1177	transmembrane transport
GCK68_06420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK68_06445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK68_06450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK68_06455	COG1120	ATPase activity
GCK68_06475	COG4160	amino acid transport
GCK68_06480	COG4215	(ABC) transporter
GCK68_06485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK68_06490	COG1126	abc transporter atp-binding protein
GCK68_06495	COG1605	Chorismate mutase
GCK68_06505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK68_06510	COG0702	epimerase
GCK68_06515	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCK68_06525	COG0028	Belongs to the TPP enzyme family
GCK68_06530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK68_06545	COG3593	DNA synthesis involved in DNA repair
GCK68_06550	COG2990	Protein conserved in bacteria
GCK68_06555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK68_06565	COG1278	Cold shock
GCK68_06580	COG0542	response to heat
GCK68_06585	COG1943	Transposase
GCK68_06595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCK68_06605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCK68_06615	COG0492	ferredoxin-NADP+ reductase activity
GCK68_06625	COG3107	peptidoglycan biosynthetic process
GCK68_06625	COG1674	ftsk spoiiie
GCK68_06635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCK68_06665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCK68_06675	COG1882	Formate acetyltransferase
GCK68_06680	COG2116	formate transmembrane transporter activity
GCK68_06685	COG1944	ATP diphosphatase activity
GCK68_06690	COG0252	asparaginase activity
GCK68_06695	COG5295	Hep Hag repeat protein
GCK68_06695	COG5295	Hep Hag repeat protein
GCK68_06720	COG0539	negative regulation of cytoplasmic translation
GCK68_06735	COG2333	competence protein COMEC
GCK68_06735	COG0658	competence protein
GCK68_06750	COG5383	Protein conserved in bacteria
GCK68_06760	COG1278	Cold shock
GCK68_06765	COG2835	tetraacyldisaccharide 4'-kinase activity
GCK68_06780	COG3173	Aminoglycoside phosphotransferase
GCK68_06795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCK68_06800	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GCK68_06805	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GCK68_06815	COG1943	Transposase
GCK68_06820	COG2989	Protein conserved in bacteria
GCK68_06825	COG3108	Peptidase M15
GCK68_06830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK68_06840	COG1448	Aminotransferase
GCK68_06860	COG0308	aminopeptidase N
GCK68_06875	COG0633	Ferredoxin
GCK68_06875	COG3217	Mosc domain protein beta barrel domain protein
GCK68_06885	COG0488	(ABC) transporter
GCK68_06890	COG2995	paraquat-inducible protein a
GCK68_06895	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK68_06895	COG3008	intermembrane lipid transfer
GCK68_06900	COG3009	Protein conserved in bacteria
GCK68_06910	COG3130	regulation of translation
GCK68_06915	COG1943	Transposase
GCK68_06950	COG1067	ATP-dependent peptidase activity
GCK68_06960	COG1943	Transposase
GCK68_06965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK68_06965	COG2885	chlorophyll binding
GCK68_06975	COG3070	regulator of competence-specific genes
GCK68_06980	COG1289	transmembrane transporter activity
GCK68_06985	COG3304	Inner membrane component domain
GCK68_06990	COG0210	DNA helicase
GCK68_07000	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GCK68_07005	COG1832	CoA-binding protein
GCK68_07025	COG2920	part of a sulfur-relay system
GCK68_07050	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_07060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCK68_07065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK68_07070	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_07075	COG3425	synthase
GCK68_07085	COG1024	Enoyl-CoA hydratase
GCK68_07090	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_07100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCK68_07105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCK68_07235	COG0488	(ABC) transporter
GCK68_07245	COG3328	transposase activity
GCK68_07255	COG0303	'Molybdopterin
GCK68_07265	COG1136	(ABC) transporter
GCK68_07295	COG0583	DNA-binding transcription factor activity
GCK68_07300	COG0477	Major facilitator Superfamily
GCK68_07310	COG2311	Membrane
GCK68_07325	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCK68_07330	COG2949	membrane
GCK68_07345	COG1346	cytolysis
GCK68_07355	COG2814	Major facilitator Superfamily
GCK68_07375	COG1943	Transposase
GCK68_07385	COG0489	protein tyrosine kinase activity
GCK68_07400	COG2982	Protein involved in outer membrane biogenesis
GCK68_07405	COG1253	flavin adenine dinucleotide binding
GCK68_07410	COG4114	ferric iron reductase
GCK68_07415	COG0076	glutamate decarboxylase activity
GCK68_07420	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GCK68_07435	COG1120	ATPase activity
GCK68_07440	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK68_07445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK68_07450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK68_07465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK68_07470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK68_07480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GCK68_07480	COG0140	phosphoribosyl-ATP diphosphatase activity
GCK68_07495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GCK68_07500	COG0131	Imidazoleglycerol-phosphate dehydratase
GCK68_07500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK68_07510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCK68_07525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK68_07530	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_07535	COG1129	ABC transporter
GCK68_07540	COG1129	ABC transporter
GCK68_07545	COG0371	Dehydrogenase
GCK68_07555	COG0531	amino acid
GCK68_07565	COG2925	Exonuclease
GCK68_07580	COG3328	transposase activity
GCK68_07585	COG1388	LysM domain
GCK68_07585	COG1470	cell adhesion involved in biofilm formation
GCK68_07590	COG2271	Major facilitator Superfamily
GCK68_07595	COG3011	Protein conserved in bacteria
GCK68_07600	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_07610	COG4948	Mandelate Racemase Muconate Lactonizing
GCK68_07630	COG0534	Mate efflux family protein
GCK68_07650	COG3122	Protein conserved in bacteria
GCK68_07675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCK68_07695	COG2223	nitrite transmembrane transporter activity
GCK68_07700	COG3328	transposase activity
GCK68_07755	COG1132	(ABC) transporter
GCK68_07770	COG2207	Transcriptional regulator
GCK68_07810	COG1113	amino acid transport
GCK68_07830	COG1278	Cold shock
GCK68_07840	COG2226	methyltransferase
GCK68_07870	COG3716	PTS system mannose fructose sorbose family IID component
GCK68_07875	COG3715	PTS system
GCK68_07880	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_07880	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK68_07895	COG1846	Transcriptional regulator
GCK68_07910	COG1012	belongs to the aldehyde dehydrogenase family
GCK68_07915	COG3384	dioxygenase
GCK68_07925	COG3971	2-oxopent-4-enoate hydratase activity
GCK68_07940	COG2368	4-hydroxyphenylacetate
GCK68_07945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCK68_07950	COG1760	l-serine dehydratase
GCK68_07975	COG0513	Belongs to the DEAD box helicase family
GCK68_07980	COG3141	response to X-ray
GCK68_07995	COG1770	oligopeptidase
GCK68_08010	COG1528	Iron-storage protein
GCK68_08015	COG2372	response to copper ion
GCK68_08045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK68_08050	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK68_08065	COG1943	Transposase
GCK68_08075	COG3418	PFAM FlgN family protein
GCK68_08080	COG2747	anti-sigma28 factor FlgM
GCK68_08090	COG1815	bacterial-type flagellum-dependent cell motility
GCK68_08095	COG1558	bacterial-type flagellum-dependent cell motility
GCK68_08100	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK68_08105	COG1749	Flagellar hook protein flgE
GCK68_08115	COG4786	Flagellar basal body rod
GCK68_08135	COG1256	bacterial-type flagellum assembly
GCK68_08145	COG2390	Transcriptional regulator
GCK68_08150	COG3347	Dehydrogenase
GCK68_08150	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_08155	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_08165	COG1129	ABC transporter
GCK68_08170	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_08175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK68_08195	COG1987	bacterial-type flagellum assembly
GCK68_08220	COG1580	Controls the rotational direction of flagella during chemotaxis
GCK68_08230	COG2882	bacterial-type flagellum organization
GCK68_08235	COG1157	protein secretion by the type III secretion system
GCK68_08245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCK68_08255	COG1677	Flagellar hook-basal body complex protein FliE
GCK68_08275	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GCK68_08280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCK68_08285	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GCK68_08320	COG1191	sigma factor activity
GCK68_08330	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GCK68_08360	COG0506	proline dehydrogenase activity
GCK68_08360	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK68_08360	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK68_08385	COG2837	iron assimilation
GCK68_08400	COG1113	amino acid transport
GCK68_08425	COG3136	membrane protein required for alginate biosynthesis
GCK68_08435	COG2197	response regulator
GCK68_08590	COG0673	inositol 2-dehydrogenase activity
GCK68_08600	COG1175	transmembrane transport
GCK68_08605	COG0395	ABC-type sugar transport system, permease component
GCK68_08665	COG0402	S-adenosylhomocysteine deaminase activity
GCK68_08685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK68_08730	COG3328	transposase activity
GCK68_08755	COG0500	methyltransferase
GCK68_08795	COG5002	protein histidine kinase activity
GCK68_08850	COG0012	GTP binding
GCK68_08865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GCK68_08890	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK68_08895	COG3094	Invasion gene expression up-regulator, SirB
GCK68_08900	COG2912	Transglutaminase-like superfamily
GCK68_08910	COG0659	secondary active sulfate transmembrane transporter activity
GCK68_08935	COG3833	ABC-type maltose transport systems, permease component
GCK68_08940	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK68_08950	COG1943	Transposase
GCK68_08960	COG0584	glycerophosphoryl diester phosphodiesterase
GCK68_08965	COG1940	carbohydrate kinase activity
GCK68_08980	COG3381	protein complex oligomerization
GCK68_08995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK68_09005	COG0728	peptidoglycan biosynthetic process
GCK68_09025	COG3102	Protein conserved in bacteria
GCK68_09045	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GCK68_09050	COG1801	Protein of unknown function DUF72
GCK68_09060	COG0494	nUDIX hydrolase
GCK68_09090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK68_09100	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GCK68_09105	COG0739	heme binding
GCK68_09110	COG1560	Kdo2-lipid A biosynthetic process
GCK68_09120	COG0469	pyruvate kinase activity
GCK68_09125	COG1737	Transcriptional regulator
GCK68_09130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCK68_09140	COG0800	Aldolase
GCK68_09155	COG0251	oxidation-reduction process
GCK68_09160	COG1199	ATP-dependent helicase activity
GCK68_09180	COG0318	PFAM AMP-dependent synthetase and ligase
GCK68_09185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GCK68_09190	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GCK68_09195	COG2894	cell division
GCK68_09210	COG2951	lytic endotransglycosylase activity
GCK68_09215	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCK68_09225	COG0582	viral genome integration into host DNA
GCK68_09320	COG3328	transposase activity
GCK68_09485	COG3328	transposase activity
GCK68_09495	COG1104	cysteine desulfurase activity
GCK68_09530	COG2719	SpoVR family
GCK68_09540	COG2814	Major facilitator Superfamily
GCK68_09550	COG0583	DNA-binding transcription factor activity
GCK68_09565	COG2766	serine protein kinase
GCK68_09575	COG3713	MltA-interacting MipA family protein
GCK68_09595	COG3139	Protein of unknown function (DUF1315)
GCK68_09600	COG1335	isochorismatase
GCK68_09605	COG0252	asparaginase activity
GCK68_09610	COG0616	signal peptide processing
GCK68_09615	COG0778	Nitroreductase
GCK68_09620	COG0709	Synthesizes selenophosphate from selenide and ATP
GCK68_09625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK68_09635	COG0494	nUDIX hydrolase
GCK68_09640	COG0708	Exodeoxyribonuclease III
GCK68_09645	COG0583	DNA-binding transcription factor activity
GCK68_09665	COG3328	transposase activity
GCK68_09670	COG0788	formyltetrahydrofolate deformylase activity
GCK68_09680	COG0745	RESPONSE REGULATOR receiver
GCK68_09695	COG1435	thymidine kinase activity
GCK68_09710	COG1943	Transposase
GCK68_09715	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GCK68_09720	COG2205	protein histidine kinase activity
GCK68_09725	COG0745	RESPONSE REGULATOR receiver
GCK68_09735	COG0531	amino acid
GCK68_09750	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GCK68_09755	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GCK68_09760	COG0589	response to stress
GCK68_09765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCK68_09770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK68_09785	COG1011	Hydrolase
GCK68_09790	COG0440	acetolactate synthase activity
GCK68_09795	COG0028	Belongs to the TPP enzyme family
GCK68_09825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK68_09835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK68_09840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK68_09855	COG1609	Transcriptional regulator
GCK68_09865	COG0038	chloride channel
GCK68_09870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK68_09875	COG1940	carbohydrate kinase activity
GCK68_09880	COG0583	DNA-binding transcription factor activity
GCK68_09885	COG2814	Major facilitator Superfamily
GCK68_09895	COG0114	fumarate hydratase activity
GCK68_09905	COG5339	Protein conserved in bacteria
GCK68_09915	COG0385	Bile acid
GCK68_09920	COG0673	inositol 2-dehydrogenase activity
GCK68_09930	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_09940	COG1879	ABC-type sugar transport system periplasmic component
GCK68_09955	COG2274	protein secretion by the type I secretion system
GCK68_09960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK68_09995	COG2207	Transcriptional regulator
GCK68_09995	COG3708	Transcriptional regulator
GCK68_10000	COG4658	electron transport chain
GCK68_10005	COG4659	FMN binding
GCK68_10015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCK68_10020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK68_10025	COG2271	Major facilitator Superfamily
GCK68_10035	COG1966	Carbon starvation protein
GCK68_10040	COG2879	small protein
GCK68_10045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCK68_10065	COG0023	Translation Initiation Factor
GCK68_10080	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GCK68_10085	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GCK68_10090	COG0671	phosphoesterase, PA-phosphatase related
GCK68_10095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GCK68_10100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCK68_10110	COG0583	DNA-binding transcription factor activity
GCK68_10115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK68_10130	COG0616	signal peptide processing
GCK68_10135	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_10145	COG1187	pseudouridine synthase activity
GCK68_10150	COG0009	L-threonylcarbamoyladenylate synthase
GCK68_10175	COG0512	Glutamine amidotransferase of anthranilate synthase
GCK68_10185	COG0135	phosphoribosylanthranilate isomerase activity
GCK68_10185	COG0134	indole-3-glycerol-phosphate synthase activity
GCK68_10205	COG3047	cAMP biosynthetic process
GCK68_10240	COG1607	acyl-coa hydrolase
GCK68_10245	COG3328	transposase activity
GCK68_10250	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GCK68_10255	COG2350	Protein conserved in bacteria
GCK68_10295	COG4608	Belongs to the ABC transporter superfamily
GCK68_10300	COG0444	Belongs to the ABC transporter superfamily
GCK68_10305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK68_10310	COG0601	transmembrane transport
GCK68_10320	COG2095	MarC family integral membrane protein
GCK68_10330	COG1012	belongs to the aldehyde dehydrogenase family
GCK68_10330	COG1454	alcohol dehydrogenase
GCK68_10380	COG3591	Belongs to the peptidase S1B family
GCK68_10395	COG1643	Atp-dependent helicase
GCK68_10405	COG2390	Transcriptional regulator
GCK68_10410	COG0246	Mannitol dehydrogenase
GCK68_10415	COG3784	Protein of unknown function (DUF1318)
GCK68_10425	COG2911	Protein conserved in bacteria
GCK68_10430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK68_10435	COG3187	Heat shock protein
GCK68_10440	COG3042	response to heat
GCK68_10445	COG1285	pathogenesis
GCK68_10455	COG0674	pyruvate-flavodoxin oxidoreductase activity
GCK68_10455	COG1013	pyruvate-flavodoxin oxidoreductase activity
GCK68_10455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GCK68_10455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK68_10465	COG0657	acetylesterase activity
GCK68_10465	COG2755	lipolytic protein G-D-S-L family
GCK68_10485	COG4166	transmembrane transport
GCK68_10490	COG2866	Carboxypeptidase
GCK68_10495	COG4948	Mandelate Racemase Muconate Lactonizing
GCK68_10500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GCK68_10505	COG1943	Transposase
GCK68_10530	COG3106	COG3106 Predicted ATPase
GCK68_10540	COG1983	PspC domain protein
GCK68_10550	COG1842	Phage shock protein A
GCK68_10555	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GCK68_10560	COG1943	Transposase
GCK68_10570	COG4166	transmembrane transport
GCK68_10575	COG4168	peptide transport system, permease
GCK68_10580	COG4171	peptide transport system, permease
GCK68_10590	COG4172	Belongs to the ABC transporter superfamily
GCK68_10595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK68_10595	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK68_10600	COG3104	oligopeptide transport
GCK68_10615	COG0625	glutathione transferase activity
GCK68_10635	COG3895	Periplasmic Protein
GCK68_10645	COG3133	Outer membrane lipoprotein
GCK68_10660	COG2194	sulfuric ester hydrolase activity
GCK68_10665	COG1309	transcriptional regulator
GCK68_10675	COG0346	lactoylglutathione lyase activity
GCK68_10680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK68_10690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GCK68_10700	COG0791	NLP P60 protein
GCK68_10705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK68_10720	COG0583	DNA-binding transcription factor activity
GCK68_10725	COG2814	Major facilitator Superfamily
GCK68_10730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCK68_10735	COG0307	riboflavin synthase, alpha
GCK68_10765	COG4238	major outer membrane lipoprotein
GCK68_10770	COG1943	Transposase
GCK68_10785	COG1376	ErfK ybiS ycfS ynhG family protein
GCK68_10785	COG1388	LysM domain
GCK68_10800	COG0719	Fe-S assembly protein
GCK68_10805	COG0396	ATPase activity
GCK68_10810	COG0719	Fe-S assembly protein
GCK68_10815	COG0316	Belongs to the HesB IscA family
GCK68_10825	COG2050	protein possibly involved in aromatic compounds catabolism
GCK68_10830	COG0277	FAD linked oxidase domain protein
GCK68_10830	COG0247	lactate metabolic process
GCK68_10835	COG0628	permease
GCK68_10845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK68_10845	COG0574	Belongs to the PEP-utilizing enzyme family
GCK68_10870	COG0791	NLP P60 protein
GCK68_10915	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GCK68_10920	COG0386	Belongs to the glutathione peroxidase family
GCK68_10935	COG0776	regulation of translation
GCK68_10940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCK68_10940	COG0072	phenylalanine-tRNA ligase activity
GCK68_10945	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GCK68_10975	COG4249	Peptidase C14 caspase catalytic subunit p20
GCK68_11000	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCK68_11005	COG1121	(ABC) transporter
GCK68_11010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK68_11015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK68_11035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK68_11040	COG3328	transposase activity
GCK68_11045	COG1917	Cupin 2, conserved barrel domain protein
GCK68_11055	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_11065	COG1175	transmembrane transport
GCK68_11070	COG0395	ABC-type sugar transport system, permease component
GCK68_11075	COG3842	ATPase activity
GCK68_11080	COG1653	transport
GCK68_11085	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK68_11090	COG1988	membrane-bound metal-dependent
GCK68_11100	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK68_11110	COG0823	Involved in the tonB-independent uptake of proteins
GCK68_11115	COG2814	Major facilitator Superfamily
GCK68_11120	COG3121	Chaperone
GCK68_11135	COG3121	Chaperone
GCK68_11140	COG3539	Fimbrial protein
GCK68_11155	COG0793	Belongs to the peptidase S41A family
GCK68_11165	COG1956	GAF domain-containing protein
GCK68_11170	COG2995	paraquat-inducible protein a
GCK68_11175	COG3008	intermembrane lipid transfer
GCK68_11195	COG3121	Chaperone
GCK68_11250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK68_11260	COG5295	Hep Hag repeat protein
GCK68_11270	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK68_11280	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GCK68_11285	COG0745	RESPONSE REGULATOR receiver
GCK68_11295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCK68_11300	COG0840	transmembrane signaling receptor activity
GCK68_11305	COG0840	transmembrane signaling receptor activity
GCK68_11325	COG2964	Protein conserved in bacteria
GCK68_11335	COG0251	oxidation-reduction process
GCK68_11340	COG2271	Major facilitator Superfamily
GCK68_11345	COG0835	chemotaxis
GCK68_11350	COG0643	Histidine kinase
GCK68_11350	COG2198	Histidine kinase
GCK68_11355	COG1360	Flagellar Motor Protein
GCK68_11380	COG1285	pathogenesis
GCK68_11395	COG1278	Cold shock
GCK68_11405	COG3321	synthase
GCK68_11405	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_11405	COG0604	alcohol dehydrogenase
GCK68_11415	COG1522	sequence-specific DNA binding
GCK68_11435	COG1733	regulation of RNA biosynthetic process
GCK68_11440	COG0702	epimerase
GCK68_11445	COG0840	transmembrane signaling receptor activity
GCK68_11460	COG0538	isocitrate dehydrogenase activity
GCK68_11465	COG1187	pseudouridine synthase activity
GCK68_11485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GCK68_11495	COG0745	RESPONSE REGULATOR receiver
GCK68_11505	COG2850	peptidyl-arginine hydroxylation
GCK68_11520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GCK68_11535	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK68_11545	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK68_11550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCK68_11555	COG3134	Outer membrane lipoprotein
GCK68_11565	COG3328	transposase activity
GCK68_11585	COG1252	NADH dehydrogenase
GCK68_11595	COG1472	Belongs to the glycosyl hydrolase 3 family
GCK68_11610	COG5633	Lipoprotein
GCK68_11615	COG0537	adenosine 5'-monophosphoramidase activity
GCK68_11620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCK68_11640	COG1943	Transposase
GCK68_11645	COG1263	PTS System
GCK68_11645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK68_11650	COG0084	hydrolase, TatD family'
GCK68_11655	COG0470	DNA polymerase III
GCK68_11665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCK68_11670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK68_11675	COG1943	Transposase
GCK68_11680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK68_11690	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_11710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GCK68_11715	COG1399	metal-binding, possibly nucleic acid-binding protein
GCK68_11725	COG0564	pseudouridine synthase activity
GCK68_11730	COG1530	ribonuclease E activity
GCK68_11735	COG3328	transposase activity
GCK68_11760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GCK68_11770	COG3328	transposase activity
GCK68_11790	COG0628	permease
GCK68_11810	COG3916	Acyl-homoserine-lactone synthase
GCK68_11815	COG2771	luxR family
GCK68_11820	COG0583	DNA-binding transcription factor activity
GCK68_11830	COG0477	Major facilitator Superfamily
GCK68_11840	COG0667	Aldo Keto reductase
GCK68_11865	COG1203	CRISPR-associated helicase, Cas3
GCK68_11870	COG1518	maintenance of DNA repeat elements
GCK68_11875	COG0668	transmembrane transport
GCK68_11895	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCK68_11900	COG0395	ABC-type sugar transport system, permease component
GCK68_11915	COG1609	Transcriptional regulator
GCK68_11925	COG3842	ATPase activity
GCK68_11935	COG3210	domain, Protein
GCK68_11940	COG3210	domain, Protein
GCK68_11960	COG3210	domain, Protein
GCK68_11980	COG3210	domain, Protein
GCK68_11985	COG2831	hemolysin activation secretion protein
GCK68_11990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK68_12000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK68_12010	COG0473	3-isopropylmalate dehydrogenase activity
GCK68_12015	COG0583	DNA-binding transcription factor activity
GCK68_12020	COG1609	Transcriptional regulator
GCK68_12025	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_12030	COG1129	ABC transporter
GCK68_12035	COG1879	ABC-type sugar transport system periplasmic component
GCK68_12040	COG1063	alcohol dehydrogenase
GCK68_12060	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK68_12090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK68_12095	COG0765	amino acid transport
GCK68_12100	COG1126	abc transporter atp-binding protein
GCK68_12145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCK68_12160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GCK68_12175	COG1169	isochorismate synthase
GCK68_12185	COG4575	ribosome binding
GCK68_12200	COG0129	dihydroxy-acid dehydratase activity
GCK68_12215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK68_12220	COG1609	Transcriptional regulator
GCK68_12240	COG3265	gluconokinase activity
GCK68_12245	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_12265	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK68_12270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCK68_12280	COG0839	Belongs to the complex I subunit 6 family
GCK68_12295	COG1034	ATP synthesis coupled electron transport
GCK68_12305	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GCK68_12315	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK68_12325	COG0583	DNA-binding transcription factor activity
GCK68_12330	COG0436	Aminotransferase
GCK68_12345	COG0471	metal ion transport
GCK68_12345	COG0490	domain, Protein
GCK68_12350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK68_12370	COG0857	belongs to the CobB CobQ family
GCK68_12370	COG0280	phosphate acetyltransferase
GCK68_12375	COG1609	Transcriptional regulator
GCK68_12395	COG3328	transposase activity
GCK68_12400	COG3037	sugar-specific permease SgaT UlaA
GCK68_12405	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GCK68_12420	COG1090	epimerase
GCK68_12425	COG4598	ABC transporter
GCK68_12430	COG4160	amino acid transport
GCK68_12435	COG4215	(ABC) transporter
GCK68_12440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK68_12445	COG0163	prenyltransferase activity
GCK68_12450	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GCK68_12455	COG1286	toxin biosynthetic process
GCK68_12460	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GCK68_12465	COG0285	dihydrofolate synthase activity
GCK68_12475	COG0586	Pfam SNARE associated Golgi protein
GCK68_12485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK68_12500	COG0697	spore germination
GCK68_12515	COG1794	racemase activity, acting on amino acids and derivatives
GCK68_12520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK68_12535	COG3101	peptidyl-lysine hydroxylation
GCK68_12540	COG0730	response to heat
GCK68_12555	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK68_12565	COG2062	phosphohistidine phosphatase, SixA
GCK68_12580	COG3691	Protein conserved in bacteria
GCK68_12595	COG3088	subunit of a heme lyase
GCK68_12595	COG4235	cytochrome complex assembly
GCK68_12600	COG3088	subunit of a heme lyase
GCK68_12600	COG4235	cytochrome complex assembly
GCK68_12605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCK68_12610	COG1138	Cytochrome C-type biogenesis protein
GCK68_12620	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK68_12625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK68_12630	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK68_12650	COG1704	LemA family
GCK68_12660	COG2824	Alkylphosphonate utilization operon protein PhnA
GCK68_12690	COG3501	Rhs element vgr protein
GCK68_12750	COG3188	usher protein
GCK68_12755	COG3328	transposase activity
GCK68_12765	COG3188	usher protein
GCK68_12770	COG3121	Chaperone
GCK68_12830	COG2951	lytic endotransglycosylase activity
GCK68_12865	COG0243	molybdopterin cofactor binding
GCK68_12870	COG0437	4 iron, 4 sulfur cluster binding
GCK68_12875	COG3302	dmso reductase anchor subunit
GCK68_12880	COG3381	protein complex oligomerization
GCK68_12910	COG3038	cytochrome b561
GCK68_12920	COG0436	Aminotransferase
GCK68_12945	COG0667	Aldo Keto reductase
GCK68_12960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK68_13000	COG1943	Transposase
GCK68_13030	COG3530	Putative quorum-sensing-regulated virulence factor
GCK68_13045	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GCK68_13050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GCK68_13055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_13065	COG2190	(PTS) system
GCK68_13070	COG1943	Transposase
GCK68_13075	COG2205	protein histidine kinase activity
GCK68_13080	COG0745	RESPONSE REGULATOR receiver
GCK68_13085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK68_13100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GCK68_13110	COG0006	proline dipeptidase activity
GCK68_13120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GCK68_13130	COG5002	protein histidine kinase activity
GCK68_13130	COG3850	Histidine kinase
GCK68_13135	COG0745	RESPONSE REGULATOR receiver
GCK68_13150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCK68_13155	COG4208	sulfate ABC transporter
GCK68_13160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GCK68_13165	COG4150	thiosulfate binding
GCK68_13175	COG1737	Transcriptional regulator
GCK68_13185	COG2731	YhcH YjgK YiaL family protein
GCK68_13195	COG4886	Leucine-rich repeat (LRR) protein
GCK68_13205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCK68_13210	COG2837	iron assimilation
GCK68_13220	COG3111	PFAM Bacterial OB fold (BOF) protein
GCK68_13265	COG3005	denitrification pathway
GCK68_13270	COG3043	anaerobic respiration
GCK68_13280	COG3062	negative regulation of establishment of protein localization
GCK68_13285	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK68_13285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK68_13290	COG2197	response regulator
GCK68_13300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK68_13310	COG1988	membrane-bound metal-dependent
GCK68_13315	COG0641	radical SAM
GCK68_13320	COG3119	arylsulfatase activity
GCK68_13335	COG1175	transmembrane transport
GCK68_13340	COG1840	ABC-type Fe3 transport system, periplasmic component
GCK68_13350	COG1393	Belongs to the ArsC family
GCK68_13360	COG1876	peptidase activity
GCK68_13385	COG2321	neutral zinc metallopeptidase
GCK68_13400	COG1943	Transposase
GCK68_13405	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GCK68_13415	COG2716	regulation of RNA biosynthetic process
GCK68_13420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCK68_13435	COG0628	permease
GCK68_13440	COG4783	chaperone-mediated protein folding
GCK68_13445	COG1393	Belongs to the ArsC family
GCK68_13455	COG1943	Transposase
GCK68_13470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCK68_13475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK68_13490	COG0581	inorganic phosphate transmembrane transporter activity
GCK68_13500	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCK68_13505	COG0248	Ppx GppA phosphatase
GCK68_13515	COG2239	Acts as a magnesium transporter
GCK68_13520	COG0443	Heat shock 70 kDa protein
GCK68_13525	COG1177	transmembrane transport
GCK68_13530	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK68_13540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCK68_13550	COG3842	ATPase activity
GCK68_13580	COG0745	RESPONSE REGULATOR receiver
GCK68_13585	COG3422	double-strand break repair
GCK68_13615	COG0351	phosphomethylpyrimidine kinase
GCK68_13630	COG3328	transposase activity
GCK68_13670	COG1943	Transposase
GCK68_13680	COG0517	IMP dehydrogenase activity
GCK68_13680	COG0516	GMP reductase activity
GCK68_13690	COG1645	bacterial-type flagellum-dependent swarming motility
GCK68_13705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK68_13710	COG2976	Protein conserved in bacteria
GCK68_13755	COG3468	outer membrane autotransporter barrel domain protein
GCK68_13760	COG3468	outer membrane autotransporter barrel domain protein
GCK68_13785	COG2975	iron-sulfur cluster assembly
GCK68_13790	COG0633	Ferredoxin
GCK68_13815	COG0822	iron-sulfur transferase activity
GCK68_13820	COG1104	cysteine desulfurase activity
GCK68_13835	COG0483	inositol monophosphate 1-phosphatase activity
GCK68_13840	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK68_13845	COG3683	transport system, periplasmic component
GCK68_13850	COG3711	transcriptional antiterminator
GCK68_13855	COG2814	Major facilitator Superfamily
GCK68_13875	COG1017	nitric oxide dioxygenase activity
GCK68_13875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK68_13905	COG0347	Belongs to the P(II) protein family
GCK68_13910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK68_13910	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCK68_13915	COG2204	response regulator
GCK68_13920	COG3170	Tfp pilus assembly protein FimV
GCK68_13925	COG2205	protein histidine kinase activity
GCK68_13935	COG1943	Transposase
GCK68_13970	COG0590	tRNA wobble adenosine to inosine editing
GCK68_13975	COG0560	Phosphoserine phosphatase
GCK68_13985	COG1737	Transcriptional regulator
GCK68_13990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK68_13995	COG1943	Transposase
GCK68_14005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GCK68_14025	COG0681	Belongs to the peptidase S26 family
GCK68_14040	COG3086	response to oxidative stress
GCK68_14045	COG3026	antisigma factor binding
GCK68_14050	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GCK68_14060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCK68_14070	COG0513	Belongs to the DEAD box helicase family
GCK68_14115	COG1984	allophanate hydrolase subunit 2
GCK68_14125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCK68_14130	COG5212	phosphodiesterase
GCK68_14140	COG3272	Protein of unknown function (DUF1722)
GCK68_14180	COG2205	protein histidine kinase activity
GCK68_14185	COG0745	RESPONSE REGULATOR receiver
GCK68_14200	COG0033	Phosphoglucomutase
GCK68_14205	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GCK68_14225	COG2169	Transcriptional regulator
GCK68_14225	COG1917	Cupin 2, conserved barrel domain protein
GCK68_14230	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCK68_14235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK68_14240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK68_14250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK68_14255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK68_14260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK68_14270	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK68_14275	COG4413	Urea transporter
GCK68_14285	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GCK68_14315	COG1124	(ABC) transporter
GCK68_14320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GCK68_14325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK68_14335	COG0747	negative chemotaxis
GCK68_14340	COG1278	Cold shock
GCK68_14380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCK68_14385	COG4175	Glycine betaine
GCK68_14390	COG4176	ABC-type proline glycine betaine transport system permease component
GCK68_14395	COG2113	Glycine betaine
GCK68_14425	COG0582	viral genome integration into host DNA
GCK68_14435	COG0596	Alpha beta hydrolase
GCK68_14455	COG0735	belongs to the Fur family
GCK68_14480	COG1943	Transposase
GCK68_14485	COG1263	PTS System
GCK68_14485	COG2190	(PTS) system
GCK68_14485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK68_14495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GCK68_14500	COG1846	Transcriptional regulator
GCK68_14500	COG1940	carbohydrate kinase activity
GCK68_14505	COG0647	UMP catabolic process
GCK68_14510	COG0367	asparagine synthase
GCK68_14550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK68_14560	COG1702	phosphate starvation-inducible protein PhoH
GCK68_14570	COG4535	Mg2 and Co2 transporter CorC
GCK68_14575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GCK68_14585	COG0765	amino acid transport
GCK68_14590	COG0765	amino acid transport
GCK68_14595	COG1126	abc transporter atp-binding protein
GCK68_14600	COG2888	peptidyl-tyrosine sulfation
GCK68_14615	COG1466	dna polymerase III delta subunit
GCK68_14625	COG0799	negative regulation of ribosome biogenesis
GCK68_14635	COG0768	penicillin binding
GCK68_14640	COG0772	Belongs to the SEDS family
GCK68_14645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK68_14650	COG1686	Belongs to the peptidase S11 family
GCK68_14675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK68_14680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK68_14685	COG1278	Cold shock
GCK68_14690	COG1278	Cold shock
GCK68_14695	COG2197	response regulator
GCK68_14720	COG5265	(ABC) transporter
GCK68_14730	COG3718	enzyme involved in inositol metabolism
GCK68_14740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK68_14745	COG0673	inositol 2-dehydrogenase activity
GCK68_14750	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_14755	COG1129	ABC transporter
GCK68_14760	COG1879	ABC-type sugar transport system periplasmic component
GCK68_14770	COG3962	Belongs to the TPP enzyme family
GCK68_14790	COG2373	Large extracellular alpha-helical protein
GCK68_14795	COG1943	Transposase
GCK68_14800	COG4953	penicillin-binding protein 1C
GCK68_14805	COG3423	Transcriptional regulator
GCK68_14860	COG3328	transposase activity
GCK68_14885	COG0656	L-ascorbic acid biosynthetic process
GCK68_14890	COG0667	Aldo Keto reductase
GCK68_14925	COG2453	phosphatase
GCK68_14925	COG0671	phosphoesterase, PA-phosphatase related
GCK68_14930	COG2267	carboxylic ester hydrolase activity
GCK68_14940	COG4589	Belongs to the CDS family
GCK68_14945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCK68_14960	COG0582	viral genome integration into host DNA
GCK68_14995	COG2501	S4 domain
GCK68_15000	COG1943	Transposase
GCK68_15010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK68_15025	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCK68_15030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GCK68_15035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GCK68_15040	COG4181	ATPase activity
GCK68_15045	COG2755	lipolytic protein G-D-S-L family
GCK68_15050	COG0300	oxidoreductase activity
GCK68_15055	COG3118	belongs to the thioredoxin family
GCK68_15060	COG0330	HflC and HflK could
GCK68_15065	COG1585	Membrane protein implicated in regulation of membrane protease activity
GCK68_15070	COG0789	Transcriptional regulator
GCK68_15075	COG2217	Heavy metal translocating P-type atpase
GCK68_15080	COG3735	TraB family
GCK68_15085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCK68_15100	COG2223	nitrite transmembrane transporter activity
GCK68_15105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK68_15105	COG4651	solute:proton antiporter activity
GCK68_15110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK68_15115	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK68_15135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK68_15185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK68_15210	COG0543	2 iron, 2 sulfur cluster binding
GCK68_15210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK68_15240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCK68_15250	COG2832	Protein of unknown function (DUF454)
GCK68_15265	COG1196	nuclear chromosome segregation
GCK68_15265	COG3264	Mechanosensitive ion channel
GCK68_15270	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GCK68_15275	COG1309	transcriptional regulator
GCK68_15280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK68_15285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK68_15295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK68_15320	COG3695	enzyme binding
GCK68_15325	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GCK68_15330	COG1946	Acyl-CoA thioesterase
GCK68_15335	COG0004	ammonium transporteR
GCK68_15340	COG0347	Belongs to the P(II) protein family
GCK68_15345	COG1132	(ABC) transporter
GCK68_15350	COG1132	(ABC) transporter
GCK68_15355	COG1522	sequence-specific DNA binding
GCK68_15370	COG4533	DNA binding
GCK68_15380	COG0824	Thioesterase
GCK68_15385	COG1555	photosystem II stabilization
GCK68_15390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK68_15395	COG0776	regulation of translation
GCK68_15400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GCK68_15425	COG0271	Belongs to the BolA IbaG family
GCK68_15430	COG3056	Lipoprotein
GCK68_15435	COG2223	nitrite transmembrane transporter activity
GCK68_15445	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCK68_15450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCK68_15455	COG1845	cytochrome c oxidase, subunit III
GCK68_15460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCK68_15470	COG2814	Major facilitator Superfamily
GCK68_15485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCK68_15490	COG0693	protein deglycase activity
GCK68_15505	COG0142	geranyltranstransferase activity
GCK68_15515	COG1943	Transposase
GCK68_15520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCK68_15525	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GCK68_15540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK68_15540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK68_15565	COG1943	Transposase
GCK68_15570	COG1943	Transposase
GCK68_15575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK68_15580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK68_15585	COG1862	Preprotein translocase
GCK68_15595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GCK68_15600	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GCK68_15605	COG0450	alkyl hydroperoxide reductase
GCK68_15630	COG0366	Alpha amylase catalytic
GCK68_15640	COG1114	Component of the transport system for branched-chain amino acids
GCK68_15650	COG5002	protein histidine kinase activity
GCK68_15655	COG0745	RESPONSE REGULATOR receiver
GCK68_15660	COG0420	3'-5' exonuclease activity
GCK68_15665	COG0419	ATPase involved in DNA repair
GCK68_15670	COG1940	carbohydrate kinase activity
GCK68_15700	COG2226	methyltransferase
GCK68_15750	COG0583	DNA-binding transcription factor activity
GCK68_15755	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK68_15775	COG1477	protein flavinylation
GCK68_15795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK68_15800	COG1805	sodium ion transport
GCK68_15805	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK68_15815	COG3034	peptidoglycan biosynthetic process
GCK68_15820	COG0121	glutamine amidotransferase
GCK68_15830	COG1960	acyl-CoA dehydrogenase activity
GCK68_15840	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
GCK68_15865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK68_15880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK68_15930	COG2814	Major facilitator Superfamily
GCK68_15935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GCK68_15945	COG1846	Transcriptional regulator
GCK68_15950	COG1566	PFAM secretion protein HlyD family protein
GCK68_15955	COG2814	Major facilitator Superfamily
GCK68_15960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK68_15965	COG3118	belongs to the thioredoxin family
GCK68_15975	COG1042	CoA-binding domain protein
GCK68_15975	COG0045	succinate-CoA ligase (ADP-forming) activity
GCK68_15975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK68_15980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK68_15985	COG5544	Lipoprotein
GCK68_16025	COG0542	response to heat
GCK68_16035	COG0564	pseudouridine synthase activity
GCK68_16045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK68_16050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCK68_16055	COG1943	Transposase
GCK68_16080	COG1605	Chorismate mutase
GCK68_16080	COG0287	Prephenate dehydrogenase
GCK68_16085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK68_16090	COG3279	Response regulator of the LytR AlgR family
GCK68_16100	COG3137	Salt-induced outer membrane protein
GCK68_16105	COG1943	Transposase
GCK68_16130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCK68_16135	COG4137	Cytochrome C assembly protein
GCK68_16140	COG4536	flavin adenine dinucleotide binding
GCK68_16145	COG1943	Transposase
GCK68_16155	COG2918	glutathione biosynthetic process
GCK68_16160	COG1238	metal cluster binding
GCK68_16165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK68_16195	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GCK68_16200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GCK68_16240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK68_16245	COG3958	Transketolase
GCK68_16250	COG3959	Transketolase, thiamine diphosphate binding domain
GCK68_16255	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_16260	COG1129	ABC transporter
GCK68_16280	COG3783	Cytochrome b(562)
GCK68_16285	COG3038	cytochrome b561
GCK68_16290	COG3381	protein complex oligomerization
GCK68_16295	COG3302	dmso reductase anchor subunit
GCK68_16300	COG0437	4 iron, 4 sulfur cluster binding
GCK68_16305	COG0243	molybdopterin cofactor binding
GCK68_16310	COG0235	Class ii aldolase
GCK68_16315	COG1349	DNA-binding transcription factor activity
GCK68_16325	COG1943	Transposase
GCK68_16330	COG1129	ABC transporter
GCK68_16335	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_16340	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_16345	COG3623	hexulose-6-phosphate isomerase
GCK68_16350	COG1070	Carbohydrate kinase
GCK68_16355	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK68_16355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK68_16365	COG0024	Methionine aminopeptidase
GCK68_16375	COG4771	TonB-dependent receptor
GCK68_16385	COG1858	cytochrome C peroxidase
GCK68_16390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK68_16410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCK68_16425	COG2376	Dihydroxyacetone kinase
GCK68_16430	COG1028	Short-chain dehydrogenase reductase Sdr
GCK68_16435	COG1063	alcohol dehydrogenase
GCK68_16440	COG0698	ribose 5-phosphate isomerase
GCK68_16445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GCK68_16450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCK68_16455	COG4942	peptidase
GCK68_16455	COG1388	LysM domain
GCK68_16480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GCK68_16495	COG0529	Catalyzes the synthesis of activated sulfate
GCK68_16550	COG0720	synthase
GCK68_16555	COG0602	queuosine metabolic process
GCK68_16575	COG3956	TIGRFAM MazG family protein
GCK68_16580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK68_16585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCK68_16595	COG4999	Histidine kinase
GCK68_16595	COG3850	Histidine kinase
GCK68_16595	COG3437	response regulator, receiver
GCK68_16595	COG2205	protein histidine kinase activity
GCK68_16600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK68_16610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK68_16620	COG2860	membrane
GCK68_16640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK68_16645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK68_16650	COG1120	ATPase activity
GCK68_16655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCK68_16660	COG1643	Atp-dependent helicase
GCK68_16665	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GCK68_16675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GCK68_16685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCK68_16690	COG0617	tRNA 3'-terminal CCA addition
GCK68_16695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GCK68_16720	COG0842	Transport permease protein
GCK68_16725	COG1131	(ABC) transporter
GCK68_16730	COG0288	reversible hydration of carbon dioxide
GCK68_16735	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GCK68_16740	COG2132	Multicopper oxidase
GCK68_16760	COG0697	spore germination
GCK68_16770	COG1049	propionate catabolic process, 2-methylcitrate cycle
GCK68_16775	COG1943	Transposase
GCK68_16780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK68_16785	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK68_16790	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GCK68_16795	COG2186	Transcriptional regulator
GCK68_16805	COG1113	amino acid transport
GCK68_16810	COG3725	Membrane protein required for beta-lactamase induction
GCK68_16815	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK68_16825	COG4969	Belongs to the N-Me-Phe pilin family
GCK68_16830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCK68_16835	COG1459	type II secretion system
GCK68_16850	COG0237	dephospho-CoA kinase activity
GCK68_16865	COG1943	Transposase
GCK68_16890	COG0582	viral genome integration into host DNA
GCK68_16900	COG0795	lipopolysaccharide-transporting ATPase activity
GCK68_16905	COG0795	lipopolysaccharide-transporting ATPase activity
GCK68_16915	COG2927	DNA polymerase III (CHI subunit)
GCK68_16920	COG0525	valine-tRNA ligase activity
GCK68_16930	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GCK68_16935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GCK68_16940	COG2731	YhcH YjgK YiaL family protein
GCK68_16950	COG0601	transmembrane transport
GCK68_16955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK68_16960	COG0444	Belongs to the ABC transporter superfamily
GCK68_16965	COG4608	Belongs to the ABC transporter superfamily
GCK68_16980	COG2188	Transcriptional regulator
GCK68_16985	COG3624	Phosphonate C-P lyase system protein PhnG
GCK68_16990	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GCK68_16995	COG3626	phosphonate metabolism
GCK68_17000	COG3627	carbon phosphorus lyase activity
GCK68_17005	COG4107	phosphonate C-P lyase system protein PhnK
GCK68_17010	COG4778	phosphonate C-P lyase system protein PhnL
GCK68_17015	COG3454	Phosphonate metabolism
GCK68_17020	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GCK68_17025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCK68_17030	COG0702	epimerase
GCK68_17045	COG3842	ATPase activity
GCK68_17050	COG0395	ABC-type sugar transport system, permease component
GCK68_17060	COG1653	transport
GCK68_17080	COG3153	acetyltransferase
GCK68_17110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK68_17120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCK68_17145	COG0513	Belongs to the DEAD box helicase family
GCK68_17190	COG0195	Participates in both transcription termination and antitermination
GCK68_17210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK68_17220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GCK68_17225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GCK68_17235	COG1534	Rna-binding protein
GCK68_17240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK68_17245	COG2027	D-alanyl-D-alanine carboxypeptidase
GCK68_17250	COG0745	RESPONSE REGULATOR receiver
GCK68_17255	COG0642	Histidine kinase
GCK68_17265	COG0697	spore germination
GCK68_17280	COG0142	geranyltranstransferase activity
GCK68_17290	COG3423	Transcriptional regulator
GCK68_17315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCK68_17325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GCK68_17330	COG2105	PFAM AIG2 family protein
GCK68_17335	COG2911	Protein conserved in bacteria
GCK68_17340	COG0729	surface antigen
GCK68_17350	COG1253	flavin adenine dinucleotide binding
GCK68_17360	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GCK68_17370	COG0737	Belongs to the 5'-nucleotidase family
GCK68_17380	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK68_17385	COG3061	Opacity-associated protein A
GCK68_17395	COG1943	Transposase
GCK68_17405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCK68_17415	COG0360	Binds together with S18 to 16S ribosomal RNA
GCK68_17425	COG1073	alpha beta
GCK68_17445	COG3650	response to hydrogen peroxide
GCK68_17450	COG1960	acyl-CoA dehydrogenase activity
GCK68_17455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK68_17460	COG0557	exoribonuclease II activity
GCK68_17475	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GCK68_17480	COG0330	HflC and HflK could
GCK68_17485	COG0330	HflC and HflK could
GCK68_17490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCK68_17510	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK68_17515	COG0802	atpase or kinase
GCK68_17520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCK68_17520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCK68_17525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCK68_17545	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GCK68_17565	COG1511	domain protein
GCK68_17565	COG3264	Mechanosensitive ion channel
GCK68_17580	COG1053	succinate dehydrogenase
GCK68_17585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCK68_17595	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GCK68_17600	COG2076	Multidrug Resistance protein
GCK68_17660	COG3383	formate dehydrogenase (NAD+) activity
GCK68_17665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK68_17670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK68_17670	COG0493	'glutamate synthase
GCK68_17680	COG1309	transcriptional regulator
GCK68_17750	COG1454	alcohol dehydrogenase
GCK68_17760	COG0629	single-stranded DNA binding
GCK68_17765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCK68_17770	COG2315	Protein conserved in bacteria
GCK68_17775	COG1448	Aminotransferase
GCK68_17780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK68_17785	COG0305	Participates in initiation and elongation during chromosome replication
GCK68_17800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK68_17805	COG0735	belongs to the Fur family
GCK68_17815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCK68_17870	COG3121	Chaperone
GCK68_17930	COG1358	cellular component organization or biogenesis
GCK68_17955	COG3721	Heme iron utilization protein
GCK68_17960	COG0702	epimerase
GCK68_17970	COG4771	TonB-dependent receptor
GCK68_17975	COG3720	iron ion transport
GCK68_17980	COG4558	Periplasmic binding protein
GCK68_17985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK68_17995	COG0626	cystathionine gamma-synthase activity
GCK68_18000	COG0814	amino acid
GCK68_18005	COG0583	DNA-binding transcription factor activity
GCK68_18010	COG0425	Belongs to the sulfur carrier protein TusA family
GCK68_18015	COG2391	methyltransferase activity
GCK68_18125	COG1301	dicarboxylic acid transport
GCK68_18135	COG3162	membrane
GCK68_18210	COG0151	Belongs to the GarS family
GCK68_18225	COG3068	Protein conserved in bacteria
GCK68_18230	COG1515	deoxyribonuclease V activity
GCK68_18255	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GCK68_18265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCK68_18290	COG1943	Transposase
GCK68_18325	COG0250	Participates in transcription elongation, termination and antitermination
GCK68_18330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK68_18385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCK68_18420	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GCK68_18425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GCK68_18435	COG1943	Transposase
GCK68_18440	COG1739	Uncharacterized protein family UPF0029
GCK68_18500	COG0805	protein transport
GCK68_18510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK68_18530	COG1322	Protein conserved in bacteria
GCK68_18535	COG0586	Pfam SNARE associated Golgi protein
GCK68_18540	COG1966	Carbon starvation protein
GCK68_18550	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GCK68_18555	COG0412	Dienelactone hydrolase
GCK68_18565	COG0583	DNA-binding transcription factor activity
GCK68_18575	COG0679	Auxin Efflux Carrier
GCK68_18580	COG0584	glycerophosphoryl diester phosphodiesterase
GCK68_18640	COG0410	ABC transporter
GCK68_18645	COG0411	ABC transporter
GCK68_18650	COG4177	L-phenylalanine transmembrane transporter activity
GCK68_18655	COG0559	Belongs to the binding-protein-dependent transport system permease family
GCK68_18660	COG0683	leucine binding
GCK68_18670	COG1943	Transposase
GCK68_18680	COG2177	Part of the ABC transporter FtsEX involved in
GCK68_18685	COG2884	Cell division ATP-binding protein ftsE
GCK68_18690	COG0552	protein localization to endoplasmic reticulum
GCK68_18690	COG0552	protein localization to endoplasmic reticulum
GCK68_18700	COG0742	ribosomal rna small subunit methyltransferase
GCK68_18705	COG3776	membrane
GCK68_18720	COG3714	YhhN family
GCK68_18735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCK68_18745	COG0247	lactate metabolic process
GCK68_18755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK68_18770	COG0584	glycerophosphoryl diester phosphodiesterase
GCK68_18780	COG0561	phosphatase activity
GCK68_18785	COG2267	carboxylic ester hydrolase activity
GCK68_18790	COG1280	lysine exporter protein (LysE YggA)
GCK68_18795	COG1280	lysine exporter protein (LysE YggA)
GCK68_18800	COG0514	ATP-dependent DNA helicase (RecQ)
GCK68_18805	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GCK68_18810	COG2050	protein possibly involved in aromatic compounds catabolism
GCK68_18820	COG0598	Magnesium transport protein CorA
GCK68_18825	COG5564	TIM-barrel signal transduction protein
GCK68_18830	COG5441	Belongs to the UPF0261 family
GCK68_18840	COG0210	DNA helicase
GCK68_18845	COG1011	Hydrolase
GCK68_18850	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GCK68_18855	COG3159	Protein conserved in bacteria
GCK68_18865	COG5567	small periplasmic lipoprotein
GCK68_18875	COG3072	Adenylate cyclase
GCK68_18890	COG1587	Uroporphyrinogen-III synthase
GCK68_18895	COG2959	enzyme of heme biosynthesis
GCK68_18900	COG3071	HemY protein
GCK68_18910	COG1943	Transposase
GCK68_18935	COG1113	amino acid transport
GCK68_18955	COG2244	polysaccharide biosynthetic process
GCK68_18960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GCK68_18965	COG0456	acetyltransferase
GCK68_18970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GCK68_18975	COG1088	dTDP-glucose 4,6-dehydratase activity
GCK68_18980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCK68_18985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCK68_18990	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK68_18995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCK68_19000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCK68_19005	COG3118	belongs to the thioredoxin family
GCK68_19030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK68_19040	COG3328	transposase activity
GCK68_19055	COG3121	Chaperone
GCK68_19070	COG3121	Chaperone
GCK68_19110	COG0583	DNA-binding transcription factor activity
GCK68_19155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK68_19160	COG3978	acetolactate synthase activity
GCK68_19185	COG3085	chromosome segregation
GCK68_19195	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_19200	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_19205	COG1129	ABC transporter
GCK68_19210	COG1879	ABC-type sugar transport system periplasmic component
GCK68_19290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK68_19290	COG0678	peroxiredoxin activity
GCK68_19295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK68_19320	COG1629	transport
GCK68_19335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCK68_19375	COG0460	homoserine dehydrogenase
GCK68_19375	COG0527	aspartate kinase activity
GCK68_19390	COG4682	membrane
GCK68_19400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCK68_19415	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK68_19430	COG1575	Belongs to the MenA family. Type 1 subfamily
GCK68_19485	COG1943	Transposase
GCK68_19505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GCK68_19510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK68_19515	COG1494	fructose-1,6-bisphosphatase
GCK68_19525	COG3152	Membrane
GCK68_19540	COG0583	DNA-binding transcription factor activity
GCK68_19545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCK68_19550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCK68_19555	COG0471	metal ion transport
GCK68_19565	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GCK68_19595	COG3678	ATP-independent chaperone mediated protein folding
GCK68_19600	COG0745	RESPONSE REGULATOR receiver
GCK68_19605	COG2205	protein histidine kinase activity
GCK68_19610	COG2169	Transcriptional regulator
GCK68_19610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK68_19615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCK68_19620	COG1045	serine acetyltransferase
GCK68_19640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK68_19645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCK68_19655	COG4942	peptidase
GCK68_19670	COG0156	8-amino-7-oxononanoate synthase activity
GCK68_19680	COG0859	PFAM glycosyl transferase family 9
GCK68_19685	COG0859	PFAM glycosyl transferase family 9
GCK68_19690	COG1519	Transferase
GCK68_19710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GCK68_19730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCK68_19755	COG1561	YicC-like family, N-terminal region
GCK68_19760	COG2860	membrane
GCK68_19765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GCK68_19780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK68_19785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK68_19790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK68_19800	COG0786	glutamate:sodium symporter activity
GCK68_19805	COG2233	PERMEase
GCK68_19810	COG2982	Protein involved in outer membrane biogenesis
GCK68_19815	COG0456	acetyltransferase
GCK68_19835	COG0583	DNA-binding transcription factor activity
GCK68_19840	COG1741	Belongs to the pirin family
GCK68_19850	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GCK68_19870	COG2823	Periplasmic or secreted lipoprotein
GCK68_19880	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GCK68_19890	COG5002	protein histidine kinase activity
GCK68_19890	COG0784	Response regulator, receiver
GCK68_19890	COG2198	Histidine kinase
GCK68_19900	COG1242	4 iron, 4 sulfur cluster binding
GCK68_19905	COG0069	glutamate synthase activity
GCK68_19905	COG0070	glutamate synthase
GCK68_19905	COG0067	glutamate synthase
GCK68_19910	COG0493	'glutamate synthase
GCK68_19920	COG2969	positive regulation of protein catabolic process
GCK68_19925	COG0625	glutathione transferase activity
GCK68_19945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GCK68_19950	COG3105	Protein conserved in bacteria
GCK68_19955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK68_19960	COG1943	Transposase
GCK68_19965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK68_19975	COG5007	Belongs to the BolA IbaG family
GCK68_19980	COG3113	response to antibiotic
GCK68_19985	COG2854	intermembrane phospholipid transfer
GCK68_19990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK68_19995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCK68_20000	COG1127	ABC transporter
GCK68_20005	COG0530	calcium, potassium:sodium antiporter activity
GCK68_20010	COG0517	IMP dehydrogenase activity
GCK68_20010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GCK68_20015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GCK68_20020	COG3117	lipopolysaccharide transmembrane transporter activity
GCK68_20025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GCK68_20030	COG1137	ATPase activity
GCK68_20035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GCK68_20045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_20060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK68_20090	COG1609	Transcriptional regulator
GCK68_20095	COG1263	PTS System
GCK68_20095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK68_20100	COG0366	Alpha amylase catalytic
GCK68_20105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK68_20110	COG3783	Cytochrome b(562)
GCK68_20120	COG0312	modulator of DNA gyrase
GCK68_20130	COG2732	(Barnase) inhibitor
GCK68_20160	COG0583	DNA-binding transcription factor activity
GCK68_20210	COG0312	modulator of DNA gyrase
GCK68_20215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK68_20220	COG3164	Protein of unknown function
GCK68_20225	COG1530	ribonuclease E activity
GCK68_20235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GCK68_20240	COG1792	Involved in formation and maintenance of cell shape
GCK68_20245	COG1077	Cell shape determining protein MreB Mrl
GCK68_20250	COG2199	diguanylate cyclase activity
GCK68_20250	COG2200	EAL domain
GCK68_20255	COG0604	alcohol dehydrogenase
GCK68_20260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCK68_20275	COG0511	ligase activity, forming carbon-carbon bonds
GCK68_20280	COG0439	Biotin carboxylase
GCK68_20285	COG3924	membrane
GCK68_20290	COG4145	pantothenate transmembrane transporter activity
GCK68_20300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK68_20305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GCK68_20335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK68_20345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK68_20350	COG3133	Outer membrane lipoprotein
GCK68_20360	COG1278	Cold shock
GCK68_20365	COG1278	Cold shock
GCK68_20370	COG1943	Transposase
GCK68_20385	COG0625	glutathione transferase activity
GCK68_20395	COG1069	ribulokinase activity
GCK68_20405	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK68_20410	COG1129	ABC transporter
GCK68_20420	COG1560	Kdo2-lipid A biosynthetic process
GCK68_20430	COG0025	NhaP-type Na H and K H
GCK68_20435	COG2252	PERMEase
GCK68_20440	COG3077	Addiction module antitoxin, RelB DinJ family
GCK68_20455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK68_20465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK68_20470	COG0431	NADPH-dependent FMN reductase
GCK68_20480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK68_20485	COG1869	D-ribose catabolic process
GCK68_20490	COG1917	Cupin 2, conserved barrel domain protein
GCK68_20490	COG2207	Transcriptional regulator
GCK68_20495	COG0673	inositol 2-dehydrogenase activity
GCK68_20515	COG3209	COG3209 Rhs family protein
GCK68_20530	COG3501	Rhs element vgr protein
GCK68_20560	COG3209	COG3209 Rhs family protein
GCK68_20575	COG3501	Rhs element vgr protein
GCK68_20720	COG1175	transmembrane transport
GCK68_20725	COG3833	ABC-type maltose transport systems, permease component
GCK68_20740	COG0527	aspartate kinase activity
GCK68_20770	COG2224	Isocitrate lyase
GCK68_20775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GCK68_20825	COG2186	Transcriptional regulator
GCK68_20830	COG0477	Major facilitator Superfamily
GCK68_20845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK68_20875	COG1522	sequence-specific DNA binding
GCK68_20880	COG0716	FMN binding
GCK68_20900	COG3312	ion transport
GCK68_20955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GCK68_20960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCK68_20965	COG0573	inorganic phosphate transmembrane transporter activity
GCK68_20970	COG0581	inorganic phosphate transmembrane transporter activity
GCK68_20980	COG0704	Plays a role in the regulation of phosphate uptake
GCK68_20990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK68_20995	COG0765	amino acid transport
GCK68_21000	COG0765	amino acid transport
GCK68_21005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK68_21015	COG2252	PERMEase
GCK68_21045	COG0706	membrane insertase activity
GCK68_21060	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GCK68_21125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GCK68_21135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK68_21280	COG3328	transposase activity
GCK68_21305	COG3344	reverse transcriptase
GCK68_21315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK68_21415	COG1475	DNA binding
GCK68_21430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GCK68_21440	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK68_21440	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK68_21475	COG3941	tape measure
GCK68_21570	COG1475	DNA binding
GCK68_21575	COG1475	DNA binding
GCK68_21580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK68_21630	COG1943	Transposase
GCK68_21670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK68_21730	COG4683	PFAM Phage derived protein Gp49-like (DUF891)