locus-tag	class	description
GCK69_00010	COG0592	DNA-directed DNA polymerase activity
GCK69_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GCK69_00020	COG0187	DNA topoisomerase II activity
GCK69_00025	COG0561	phosphatase activity
GCK69_00045	COG2423	ornithine cyclodeaminase activity
GCK69_00050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCK69_00065	COG5645	(Lipo)protein
GCK69_00085	COG3977	Valine--pyruvate aminotransferase
GCK69_00105	COG0366	Alpha amylase catalytic
GCK69_00125	COG2885	chlorophyll binding
GCK69_00135	COG2818	Glycosylase
GCK69_00160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_00160	COG2213	PTS system mannitol-specific
GCK69_00170	COG3722	fumarate hydratase activity
GCK69_00195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK69_00210	COG0437	4 iron, 4 sulfur cluster binding
GCK69_00215	COG2864	formate dehydrogenase
GCK69_00230	COG3276	selenocysteine insertion sequence binding
GCK69_00275	COG3274	enterobacterial common antigen metabolic process
GCK69_00290	COG3121	Chaperone
GCK69_00300	COG1070	Carbohydrate kinase
GCK69_00310	COG4213	ABC transporter substrate-binding protein
GCK69_00320	COG4214	carbohydrate transport
GCK69_00325	COG1609	Transcriptional regulator
GCK69_00325	COG2207	Transcriptional regulator
GCK69_00335	COG0582	viral genome integration into host DNA
GCK69_00385	COG4604	ABC transporter, ATP-binding protein
GCK69_00390	COG4605	iron ion homeostasis
GCK69_00400	COG4607	ABC-type enterochelin transport system periplasmic component
GCK69_00415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GCK69_00430	COG2986	histidine ammonia-lyase
GCK69_00445	COG2194	sulfuric ester hydrolase activity
GCK69_00450	COG2197	response regulator
GCK69_00455	COG3851	Histidine kinase
GCK69_00460	COG2271	Major facilitator Superfamily
GCK69_00475	COG2831	hemolysin activation secretion protein
GCK69_00485	COG0747	negative chemotaxis
GCK69_00490	COG0601	transmembrane transport
GCK69_00495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK69_00500	COG0444	Belongs to the ABC transporter superfamily
GCK69_00505	COG4608	Belongs to the ABC transporter superfamily
GCK69_00510	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK69_00515	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK69_00520	COG2200	EAL domain
GCK69_00520	COG2199	diguanylate cyclase activity
GCK69_00525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK69_00545	COG0612	Peptidase, M16
GCK69_00550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK69_00555	COG1942	4-Oxalocrotonate Tautomerase
GCK69_00560	COG2200	EAL domain
GCK69_00565	COG2982	Protein involved in outer membrane biogenesis
GCK69_00570	COG2134	cdp-diacylglycerol pyrophosphatase
GCK69_00575	COG1295	ribonuclease BN
GCK69_00600	COG1929	Belongs to the glycerate kinase type-1 family
GCK69_00605	COG2610	gluconate transmembrane transporter activity
GCK69_00615	COG3835	regulator
GCK69_00620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK69_00625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GCK69_00630	COG0339	signal peptide processing
GCK69_00650	COG0589	response to stress
GCK69_00665	COG0306	phosphate transporter
GCK69_00670	COG2081	HI0933 family
GCK69_00685	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_00690	COG1879	ABC-type sugar transport system periplasmic component
GCK69_00700	COG0191	fructose-bisphosphate aldolase activity
GCK69_00710	COG0745	RESPONSE REGULATOR receiver
GCK69_00725	COG1741	Belongs to the pirin family
GCK69_00730	COG1609	Transcriptional regulator
GCK69_00735	COG2610	gluconate transmembrane transporter activity
GCK69_00740	COG3265	gluconokinase activity
GCK69_00760	COG2095	MarC family integral membrane protein
GCK69_00765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK69_00795	COG3275	phosphorelay sensor kinase activity
GCK69_00820	COG0058	SHG alpha-glucan phosphorylase activity
GCK69_00825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK69_00860	COG1349	DNA-binding transcription factor activity
GCK69_00880	COG0058	SHG alpha-glucan phosphorylase activity
GCK69_00885	COG0058	SHG alpha-glucan phosphorylase activity
GCK69_00890	COG1640	4-alpha-glucanotransferase
GCK69_00925	COG1918	ferrous iron import across plasma membrane
GCK69_00930	COG2183	response to ionizing radiation
GCK69_00935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK69_00940	COG0745	RESPONSE REGULATOR receiver
GCK69_00960	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GCK69_00965	COG1011	Hydrolase
GCK69_00975	COG0494	nUDIX hydrolase
GCK69_00980	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GCK69_01010	COG4796	Type ii and iii secretion system protein
GCK69_01035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCK69_01040	COG0546	phosphoglycolate phosphatase activity
GCK69_01045	COG0180	Tryptophanyl-tRNA synthetase
GCK69_01060	COG2146	nitrite reductase [NAD(P)H] activity
GCK69_01065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCK69_01070	COG0402	S-adenosylhomocysteine deaminase activity
GCK69_01090	COG1486	melibiose metabolic process
GCK69_01095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK69_01100	COG0433	COG0433 Predicted ATPase
GCK69_01115	COG1289	transmembrane transporter activity
GCK69_01125	COG1765	OsmC-like protein
GCK69_01135	COG3954	Phosphoribulokinase
GCK69_01145	COG0429	hydrolase of the alpha beta-hydrolase fold
GCK69_01155	COG4521	taurine ABC transporter
GCK69_01165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK69_01170	COG2175	clavaminate synthase activity
GCK69_01180	COG1216	Glycosyl transferase, family 2
GCK69_01190	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK69_01200	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GCK69_01205	COG1047	Peptidyl-prolyl cis-trans
GCK69_01220	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK69_01225	COG2964	Protein conserved in bacteria
GCK69_01245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GCK69_01250	COG0049	tRNA binding
GCK69_01265	COG1943	Transposase
GCK69_01285	COG0051	transcription antitermination factor activity, RNA binding
GCK69_01310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GCK69_01320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GCK69_01325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCK69_01335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GCK69_01340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GCK69_01380	COG1841	ribosomal large subunit assembly
GCK69_01390	COG0201	protein transport
GCK69_01395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK69_01410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GCK69_01425	COG0789	Transcriptional regulator
GCK69_01430	COG3036	rescue of stalled ribosome
GCK69_01440	COG0569	domain protein
GCK69_01460	COG0758	DNA mediated transformation
GCK69_01470	COG0551	DNA topoisomerase type I activity
GCK69_01485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCK69_01545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GCK69_01550	COG2224	Isocitrate lyase
GCK69_01580	COG0527	aspartate kinase activity
GCK69_01595	COG3833	ABC-type maltose transport systems, permease component
GCK69_01600	COG1175	transmembrane transport
GCK69_01730	COG3501	Rhs element vgr protein
GCK69_01775	COG3501	Rhs element vgr protein
GCK69_01790	COG3209	COG3209 Rhs family protein
GCK69_01810	COG0673	inositol 2-dehydrogenase activity
GCK69_01815	COG2207	Transcriptional regulator
GCK69_01815	COG1917	Cupin 2, conserved barrel domain protein
GCK69_01820	COG1869	D-ribose catabolic process
GCK69_01825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK69_01835	COG0431	NADPH-dependent FMN reductase
GCK69_01840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK69_01850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK69_01865	COG3077	Addiction module antitoxin, RelB DinJ family
GCK69_01870	COG2252	PERMEase
GCK69_01875	COG0025	NhaP-type Na H and K H
GCK69_01885	COG1560	Kdo2-lipid A biosynthetic process
GCK69_01895	COG1129	ABC transporter
GCK69_01900	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_01910	COG1069	ribulokinase activity
GCK69_01920	COG0625	glutathione transferase activity
GCK69_01940	COG1278	Cold shock
GCK69_01945	COG1278	Cold shock
GCK69_01955	COG3133	Outer membrane lipoprotein
GCK69_01960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK69_01970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK69_02000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GCK69_02005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK69_02015	COG4145	pantothenate transmembrane transporter activity
GCK69_02020	COG3924	membrane
GCK69_02025	COG0439	Biotin carboxylase
GCK69_02030	COG0511	ligase activity, forming carbon-carbon bonds
GCK69_02045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCK69_02050	COG0604	alcohol dehydrogenase
GCK69_02055	COG2199	diguanylate cyclase activity
GCK69_02055	COG2200	EAL domain
GCK69_02060	COG1077	Cell shape determining protein MreB Mrl
GCK69_02065	COG1792	Involved in formation and maintenance of cell shape
GCK69_02070	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GCK69_02080	COG1530	ribonuclease E activity
GCK69_02085	COG3164	Protein of unknown function
GCK69_02090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK69_02095	COG0312	modulator of DNA gyrase
GCK69_02150	COG0583	DNA-binding transcription factor activity
GCK69_02180	COG2732	(Barnase) inhibitor
GCK69_02190	COG0312	modulator of DNA gyrase
GCK69_02200	COG3783	Cytochrome b(562)
GCK69_02205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK69_02210	COG0366	Alpha amylase catalytic
GCK69_02215	COG1263	PTS System
GCK69_02215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK69_02220	COG1609	Transcriptional regulator
GCK69_02250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_02265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_02275	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GCK69_02280	COG1137	ATPase activity
GCK69_02285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GCK69_02290	COG3117	lipopolysaccharide transmembrane transporter activity
GCK69_02295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GCK69_02300	COG0517	IMP dehydrogenase activity
GCK69_02300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GCK69_02305	COG0530	calcium, potassium:sodium antiporter activity
GCK69_02310	COG1127	ABC transporter
GCK69_02315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCK69_02320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK69_02325	COG2854	intermembrane phospholipid transfer
GCK69_02330	COG3113	response to antibiotic
GCK69_02335	COG5007	Belongs to the BolA IbaG family
GCK69_02345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK69_02350	COG1943	Transposase
GCK69_02355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK69_02360	COG3105	Protein conserved in bacteria
GCK69_02365	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GCK69_02385	COG0625	glutathione transferase activity
GCK69_02390	COG2969	positive regulation of protein catabolic process
GCK69_02400	COG0493	'glutamate synthase
GCK69_02405	COG0067	glutamate synthase
GCK69_02405	COG0070	glutamate synthase
GCK69_02405	COG0069	glutamate synthase activity
GCK69_02410	COG1242	4 iron, 4 sulfur cluster binding
GCK69_02420	COG0784	Response regulator, receiver
GCK69_02420	COG2198	Histidine kinase
GCK69_02420	COG5002	protein histidine kinase activity
GCK69_02430	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GCK69_02440	COG2823	Periplasmic or secreted lipoprotein
GCK69_02460	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GCK69_02470	COG1741	Belongs to the pirin family
GCK69_02475	COG0583	DNA-binding transcription factor activity
GCK69_02505	COG3162	membrane
GCK69_02515	COG1301	dicarboxylic acid transport
GCK69_02625	COG2391	methyltransferase activity
GCK69_02630	COG0425	Belongs to the sulfur carrier protein TusA family
GCK69_02635	COG0583	DNA-binding transcription factor activity
GCK69_02640	COG0814	amino acid
GCK69_02645	COG0626	cystathionine gamma-synthase activity
GCK69_02655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK69_02660	COG4558	Periplasmic binding protein
GCK69_02665	COG3720	iron ion transport
GCK69_02670	COG4771	TonB-dependent receptor
GCK69_02680	COG0702	epimerase
GCK69_02685	COG3721	Heme iron utilization protein
GCK69_02710	COG1358	cellular component organization or biogenesis
GCK69_02770	COG3121	Chaperone
GCK69_02820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCK69_02830	COG0735	belongs to the Fur family
GCK69_02835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK69_02850	COG0305	Participates in initiation and elongation during chromosome replication
GCK69_02855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK69_02860	COG1448	Aminotransferase
GCK69_02865	COG2315	Protein conserved in bacteria
GCK69_02870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCK69_02875	COG0629	single-stranded DNA binding
GCK69_02885	COG1454	alcohol dehydrogenase
GCK69_02955	COG1309	transcriptional regulator
GCK69_02965	COG0493	'glutamate synthase
GCK69_02965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK69_02970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK69_02975	COG3383	formate dehydrogenase (NAD+) activity
GCK69_02990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GCK69_03035	COG2076	Multidrug Resistance protein
GCK69_03040	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GCK69_03050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCK69_03055	COG1053	succinate dehydrogenase
GCK69_03070	COG3264	Mechanosensitive ion channel
GCK69_03070	COG1511	domain protein
GCK69_03090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GCK69_03110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCK69_03115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCK69_03115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCK69_03120	COG0802	atpase or kinase
GCK69_03125	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK69_03145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCK69_03150	COG0330	HflC and HflK could
GCK69_03155	COG0330	HflC and HflK could
GCK69_03160	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GCK69_03175	COG0557	exoribonuclease II activity
GCK69_03180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK69_03185	COG1960	acyl-CoA dehydrogenase activity
GCK69_03190	COG3650	response to hydrogen peroxide
GCK69_03210	COG1073	alpha beta
GCK69_03220	COG0360	Binds together with S18 to 16S ribosomal RNA
GCK69_03230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCK69_03240	COG1943	Transposase
GCK69_03250	COG3061	Opacity-associated protein A
GCK69_03255	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK69_03265	COG0737	Belongs to the 5'-nucleotidase family
GCK69_03275	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GCK69_03285	COG1253	flavin adenine dinucleotide binding
GCK69_03295	COG0729	surface antigen
GCK69_03300	COG2911	Protein conserved in bacteria
GCK69_03305	COG2105	PFAM AIG2 family protein
GCK69_03310	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GCK69_03315	COG1943	Transposase
GCK69_03325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCK69_03350	COG3423	Transcriptional regulator
GCK69_03360	COG0142	geranyltranstransferase activity
GCK69_03375	COG0697	spore germination
GCK69_03385	COG0642	Histidine kinase
GCK69_03390	COG0745	RESPONSE REGULATOR receiver
GCK69_03395	COG2027	D-alanyl-D-alanine carboxypeptidase
GCK69_03400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK69_03405	COG1534	Rna-binding protein
GCK69_03415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GCK69_03420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GCK69_03430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK69_03450	COG0195	Participates in both transcription termination and antitermination
GCK69_03495	COG0513	Belongs to the DEAD box helicase family
GCK69_03520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCK69_03530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK69_03560	COG3153	acetyltransferase
GCK69_03580	COG1653	transport
GCK69_03590	COG0395	ABC-type sugar transport system, permease component
GCK69_03595	COG3842	ATPase activity
GCK69_03610	COG0702	epimerase
GCK69_03615	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCK69_03620	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GCK69_03625	COG3454	Phosphonate metabolism
GCK69_03630	COG4778	phosphonate C-P lyase system protein PhnL
GCK69_03635	COG4107	phosphonate C-P lyase system protein PhnK
GCK69_03640	COG3627	carbon phosphorus lyase activity
GCK69_03645	COG3626	phosphonate metabolism
GCK69_03650	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GCK69_03655	COG3624	Phosphonate C-P lyase system protein PhnG
GCK69_03660	COG2188	Transcriptional regulator
GCK69_03675	COG4608	Belongs to the ABC transporter superfamily
GCK69_03680	COG0444	Belongs to the ABC transporter superfamily
GCK69_03685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK69_03690	COG0601	transmembrane transport
GCK69_03700	COG2731	YhcH YjgK YiaL family protein
GCK69_03705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GCK69_03710	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GCK69_03720	COG0525	valine-tRNA ligase activity
GCK69_03725	COG2927	DNA polymerase III (CHI subunit)
GCK69_03735	COG0795	lipopolysaccharide-transporting ATPase activity
GCK69_03740	COG0795	lipopolysaccharide-transporting ATPase activity
GCK69_03750	COG0582	viral genome integration into host DNA
GCK69_03790	COG0237	dephospho-CoA kinase activity
GCK69_03805	COG1459	type II secretion system
GCK69_03810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCK69_03815	COG4969	Belongs to the N-Me-Phe pilin family
GCK69_03825	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK69_03830	COG3725	Membrane protein required for beta-lactamase induction
GCK69_03835	COG1113	amino acid transport
GCK69_03845	COG2186	Transcriptional regulator
GCK69_03850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GCK69_03855	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK69_03860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK69_03870	COG1049	propionate catabolic process, 2-methylcitrate cycle
GCK69_03880	COG0697	spore germination
GCK69_03900	COG2132	Multicopper oxidase
GCK69_03905	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GCK69_03910	COG0288	reversible hydration of carbon dioxide
GCK69_03915	COG1131	(ABC) transporter
GCK69_03920	COG0842	Transport permease protein
GCK69_03945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GCK69_03950	COG0617	tRNA 3'-terminal CCA addition
GCK69_03955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCK69_03965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GCK69_03975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GCK69_03980	COG1643	Atp-dependent helicase
GCK69_03985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCK69_03990	COG1120	ATPase activity
GCK69_03995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK69_04000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK69_04020	COG2860	membrane
GCK69_04030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK69_04040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK69_04045	COG4999	Histidine kinase
GCK69_04045	COG3437	response regulator, receiver
GCK69_04045	COG2205	protein histidine kinase activity
GCK69_04045	COG3850	Histidine kinase
GCK69_04055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCK69_04060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK69_04065	COG3956	TIGRFAM MazG family protein
GCK69_04085	COG0602	queuosine metabolic process
GCK69_04090	COG0720	synthase
GCK69_04145	COG0529	Catalyzes the synthesis of activated sulfate
GCK69_04160	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GCK69_04185	COG1388	LysM domain
GCK69_04185	COG4942	peptidase
GCK69_04195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GCK69_04200	COG0698	ribose 5-phosphate isomerase
GCK69_04205	COG1063	alcohol dehydrogenase
GCK69_04210	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_04215	COG2376	Dihydroxyacetone kinase
GCK69_04230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCK69_04250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK69_04255	COG1858	cytochrome C peroxidase
GCK69_04265	COG4771	TonB-dependent receptor
GCK69_04275	COG0024	Methionine aminopeptidase
GCK69_04285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK69_04285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK69_04290	COG1070	Carbohydrate kinase
GCK69_04295	COG3623	hexulose-6-phosphate isomerase
GCK69_04300	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_04305	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_04310	COG1129	ABC transporter
GCK69_04315	COG1943	Transposase
GCK69_04325	COG1349	DNA-binding transcription factor activity
GCK69_04330	COG0235	Class ii aldolase
GCK69_04335	COG0243	molybdopterin cofactor binding
GCK69_04340	COG0437	4 iron, 4 sulfur cluster binding
GCK69_04345	COG3302	dmso reductase anchor subunit
GCK69_04350	COG3381	protein complex oligomerization
GCK69_04355	COG3038	cytochrome b561
GCK69_04360	COG3783	Cytochrome b(562)
GCK69_04380	COG1129	ABC transporter
GCK69_04385	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_04390	COG3959	Transketolase, thiamine diphosphate binding domain
GCK69_04395	COG3958	Transketolase
GCK69_04400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK69_04440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GCK69_04445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GCK69_04480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK69_04485	COG1238	metal cluster binding
GCK69_04490	COG2918	glutathione biosynthetic process
GCK69_04500	COG4536	flavin adenine dinucleotide binding
GCK69_04505	COG4137	Cytochrome C assembly protein
GCK69_04510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCK69_04540	COG3137	Salt-induced outer membrane protein
GCK69_04550	COG3279	Response regulator of the LytR AlgR family
GCK69_04555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK69_04560	COG0287	Prephenate dehydrogenase
GCK69_04560	COG1605	Chorismate mutase
GCK69_04585	COG1943	Transposase
GCK69_04590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCK69_04595	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK69_04605	COG0564	pseudouridine synthase activity
GCK69_04615	COG0542	response to heat
GCK69_04655	COG5544	Lipoprotein
GCK69_04660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK69_04665	COG0045	succinate-CoA ligase (ADP-forming) activity
GCK69_04665	COG1042	CoA-binding domain protein
GCK69_04665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK69_04675	COG3118	belongs to the thioredoxin family
GCK69_04680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK69_04685	COG2814	Major facilitator Superfamily
GCK69_04690	COG1566	PFAM secretion protein HlyD family protein
GCK69_04695	COG1846	Transcriptional regulator
GCK69_04705	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GCK69_04710	COG2814	Major facilitator Superfamily
GCK69_04760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK69_04785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK69_04810	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
GCK69_04820	COG1960	acyl-CoA dehydrogenase activity
GCK69_04830	COG0121	glutamine amidotransferase
GCK69_04835	COG3034	peptidoglycan biosynthetic process
GCK69_04845	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK69_04850	COG1805	sodium ion transport
GCK69_04855	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK69_04875	COG1477	protein flavinylation
GCK69_04895	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK69_04900	COG0583	DNA-binding transcription factor activity
GCK69_04950	COG2226	methyltransferase
GCK69_04980	COG1940	carbohydrate kinase activity
GCK69_04985	COG0419	ATPase involved in DNA repair
GCK69_04990	COG0420	3'-5' exonuclease activity
GCK69_04995	COG0745	RESPONSE REGULATOR receiver
GCK69_05000	COG5002	protein histidine kinase activity
GCK69_05010	COG1114	Component of the transport system for branched-chain amino acids
GCK69_05020	COG0366	Alpha amylase catalytic
GCK69_05045	COG0450	alkyl hydroperoxide reductase
GCK69_05050	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GCK69_05055	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GCK69_05065	COG1862	Preprotein translocase
GCK69_05070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK69_05075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK69_05080	COG1943	Transposase
GCK69_05085	COG1943	Transposase
GCK69_05110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK69_05110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK69_05125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GCK69_05130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCK69_05145	COG0142	geranyltranstransferase activity
GCK69_05160	COG0693	protein deglycase activity
GCK69_05165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCK69_05180	COG2814	Major facilitator Superfamily
GCK69_05190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCK69_05195	COG1845	cytochrome c oxidase, subunit III
GCK69_05200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCK69_05205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCK69_05215	COG2223	nitrite transmembrane transporter activity
GCK69_05220	COG3056	Lipoprotein
GCK69_05225	COG0271	Belongs to the BolA IbaG family
GCK69_05250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GCK69_05255	COG0776	regulation of translation
GCK69_05260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK69_05265	COG1555	photosystem II stabilization
GCK69_05270	COG0824	Thioesterase
GCK69_05280	COG4533	DNA binding
GCK69_05295	COG1522	sequence-specific DNA binding
GCK69_05300	COG1132	(ABC) transporter
GCK69_05305	COG1132	(ABC) transporter
GCK69_05310	COG0347	Belongs to the P(II) protein family
GCK69_05315	COG0004	ammonium transporteR
GCK69_05320	COG1946	Acyl-CoA thioesterase
GCK69_05325	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GCK69_05330	COG3695	enzyme binding
GCK69_05355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK69_05365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK69_05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK69_05375	COG1309	transcriptional regulator
GCK69_05380	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GCK69_05385	COG1196	nuclear chromosome segregation
GCK69_05385	COG3264	Mechanosensitive ion channel
GCK69_05400	COG2832	Protein of unknown function (DUF454)
GCK69_05410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCK69_05440	COG0543	2 iron, 2 sulfur cluster binding
GCK69_05440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK69_05465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK69_05510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK69_05530	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK69_05535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK69_05540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK69_05540	COG4651	solute:proton antiporter activity
GCK69_05545	COG2223	nitrite transmembrane transporter activity
GCK69_05560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCK69_05565	COG3735	TraB family
GCK69_05570	COG2217	Heavy metal translocating P-type atpase
GCK69_05575	COG0789	Transcriptional regulator
GCK69_05580	COG1585	Membrane protein implicated in regulation of membrane protease activity
GCK69_05585	COG0330	HflC and HflK could
GCK69_05590	COG3118	belongs to the thioredoxin family
GCK69_05595	COG0300	oxidoreductase activity
GCK69_05600	COG2755	lipolytic protein G-D-S-L family
GCK69_05605	COG4181	ATPase activity
GCK69_05610	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GCK69_05615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GCK69_05620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCK69_05635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK69_05645	COG1943	Transposase
GCK69_05650	COG2501	S4 domain
GCK69_05670	COG3328	transposase activity
GCK69_05690	COG0582	viral genome integration into host DNA
GCK69_05705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCK69_05710	COG4589	Belongs to the CDS family
GCK69_05720	COG2267	carboxylic ester hydrolase activity
GCK69_05725	COG2453	phosphatase
GCK69_05725	COG0671	phosphoesterase, PA-phosphatase related
GCK69_05760	COG0667	Aldo Keto reductase
GCK69_05765	COG0656	L-ascorbic acid biosynthetic process
GCK69_05790	COG3328	transposase activity
GCK69_05845	COG3423	Transcriptional regulator
GCK69_05850	COG4953	penicillin-binding protein 1C
GCK69_05855	COG1943	Transposase
GCK69_05860	COG2373	Large extracellular alpha-helical protein
GCK69_05880	COG3962	Belongs to the TPP enzyme family
GCK69_05890	COG1879	ABC-type sugar transport system periplasmic component
GCK69_05895	COG1129	ABC transporter
GCK69_05900	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_05905	COG0673	inositol 2-dehydrogenase activity
GCK69_05910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK69_05920	COG3718	enzyme involved in inositol metabolism
GCK69_05930	COG5265	(ABC) transporter
GCK69_05955	COG2197	response regulator
GCK69_05960	COG3328	transposase activity
GCK69_05965	COG1278	Cold shock
GCK69_05970	COG1278	Cold shock
GCK69_05975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK69_05980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK69_06005	COG1686	Belongs to the peptidase S11 family
GCK69_06010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK69_06015	COG0772	Belongs to the SEDS family
GCK69_06020	COG0768	penicillin binding
GCK69_06030	COG0799	negative regulation of ribosome biogenesis
GCK69_06040	COG1466	dna polymerase III delta subunit
GCK69_06055	COG2888	peptidyl-tyrosine sulfation
GCK69_06060	COG1126	abc transporter atp-binding protein
GCK69_06065	COG0765	amino acid transport
GCK69_06070	COG0765	amino acid transport
GCK69_06080	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GCK69_06085	COG4535	Mg2 and Co2 transporter CorC
GCK69_06095	COG1702	phosphate starvation-inducible protein PhoH
GCK69_06105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK69_06145	COG0367	asparagine synthase
GCK69_06150	COG0647	UMP catabolic process
GCK69_06155	COG1940	carbohydrate kinase activity
GCK69_06155	COG1846	Transcriptional regulator
GCK69_06160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GCK69_06170	COG1263	PTS System
GCK69_06170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK69_06170	COG2190	(PTS) system
GCK69_06175	COG1943	Transposase
GCK69_06200	COG0735	belongs to the Fur family
GCK69_06220	COG0596	Alpha beta hydrolase
GCK69_06230	COG0582	viral genome integration into host DNA
GCK69_06260	COG2113	Glycine betaine
GCK69_06265	COG4176	ABC-type proline glycine betaine transport system permease component
GCK69_06270	COG4175	Glycine betaine
GCK69_06275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCK69_06315	COG1278	Cold shock
GCK69_06320	COG0747	negative chemotaxis
GCK69_06330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK69_06335	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GCK69_06340	COG1124	(ABC) transporter
GCK69_06370	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GCK69_06380	COG4413	Urea transporter
GCK69_06385	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK69_06395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK69_06400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK69_06405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK69_06415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK69_06420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK69_06425	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCK69_06430	COG2169	Transcriptional regulator
GCK69_06430	COG1917	Cupin 2, conserved barrel domain protein
GCK69_06450	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GCK69_06455	COG0033	Phosphoglucomutase
GCK69_06470	COG0745	RESPONSE REGULATOR receiver
GCK69_06475	COG2205	protein histidine kinase activity
GCK69_06515	COG3272	Protein of unknown function (DUF1722)
GCK69_06525	COG5212	phosphodiesterase
GCK69_06530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCK69_06540	COG1984	allophanate hydrolase subunit 2
GCK69_06590	COG0513	Belongs to the DEAD box helicase family
GCK69_06600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCK69_06610	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GCK69_06615	COG3026	antisigma factor binding
GCK69_06620	COG3086	response to oxidative stress
GCK69_06635	COG0681	Belongs to the peptidase S26 family
GCK69_06655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GCK69_06665	COG1943	Transposase
GCK69_06670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK69_06675	COG1737	Transcriptional regulator
GCK69_06685	COG0560	Phosphoserine phosphatase
GCK69_06690	COG0590	tRNA wobble adenosine to inosine editing
GCK69_06735	COG2205	protein histidine kinase activity
GCK69_06740	COG3170	Tfp pilus assembly protein FimV
GCK69_06745	COG2204	response regulator
GCK69_06750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK69_06750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCK69_06755	COG0347	Belongs to the P(II) protein family
GCK69_06765	COG1017	nitric oxide dioxygenase activity
GCK69_06765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK69_06785	COG2814	Major facilitator Superfamily
GCK69_06790	COG3711	transcriptional antiterminator
GCK69_06795	COG3683	transport system, periplasmic component
GCK69_06800	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK69_06805	COG0483	inositol monophosphate 1-phosphatase activity
GCK69_06820	COG1104	cysteine desulfurase activity
GCK69_06825	COG0822	iron-sulfur transferase activity
GCK69_06845	COG0443	Heat shock 70 kDa protein
GCK69_06850	COG0633	Ferredoxin
GCK69_06855	COG2975	iron-sulfur cluster assembly
GCK69_06880	COG3468	outer membrane autotransporter barrel domain protein
GCK69_06885	COG3468	outer membrane autotransporter barrel domain protein
GCK69_06930	COG2976	Protein conserved in bacteria
GCK69_06935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK69_06950	COG1645	bacterial-type flagellum-dependent swarming motility
GCK69_06960	COG0516	GMP reductase activity
GCK69_06960	COG0517	IMP dehydrogenase activity
GCK69_06970	COG1943	Transposase
GCK69_07010	COG3328	transposase activity
GCK69_07025	COG0351	phosphomethylpyrimidine kinase
GCK69_07055	COG3422	double-strand break repair
GCK69_07060	COG0745	RESPONSE REGULATOR receiver
GCK69_07090	COG3842	ATPase activity
GCK69_07100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCK69_07110	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK69_07115	COG1177	transmembrane transport
GCK69_07120	COG0443	Heat shock 70 kDa protein
GCK69_07125	COG2239	Acts as a magnesium transporter
GCK69_07135	COG0248	Ppx GppA phosphatase
GCK69_07140	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCK69_07150	COG0581	inorganic phosphate transmembrane transporter activity
GCK69_07165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK69_07170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCK69_07185	COG1943	Transposase
GCK69_07195	COG1393	Belongs to the ArsC family
GCK69_07200	COG4783	chaperone-mediated protein folding
GCK69_07205	COG0628	permease
GCK69_07220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCK69_07225	COG2716	regulation of RNA biosynthetic process
GCK69_07235	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GCK69_07240	COG1943	Transposase
GCK69_07255	COG2321	neutral zinc metallopeptidase
GCK69_07280	COG1876	peptidase activity
GCK69_07290	COG1393	Belongs to the ArsC family
GCK69_07300	COG1840	ABC-type Fe3 transport system, periplasmic component
GCK69_07305	COG1175	transmembrane transport
GCK69_07320	COG3119	arylsulfatase activity
GCK69_07325	COG0641	radical SAM
GCK69_07330	COG1988	membrane-bound metal-dependent
GCK69_07340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK69_07350	COG2197	response regulator
GCK69_07355	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK69_07355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK69_07360	COG3062	negative regulation of establishment of protein localization
GCK69_07370	COG3043	anaerobic respiration
GCK69_07375	COG3005	denitrification pathway
GCK69_07420	COG3111	PFAM Bacterial OB fold (BOF) protein
GCK69_07430	COG2837	iron assimilation
GCK69_07435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCK69_07445	COG4886	Leucine-rich repeat (LRR) protein
GCK69_07455	COG2731	YhcH YjgK YiaL family protein
GCK69_07465	COG1737	Transcriptional regulator
GCK69_07475	COG4150	thiosulfate binding
GCK69_07480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GCK69_07485	COG4208	sulfate ABC transporter
GCK69_07490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCK69_07505	COG0745	RESPONSE REGULATOR receiver
GCK69_07510	COG5002	protein histidine kinase activity
GCK69_07510	COG3850	Histidine kinase
GCK69_07520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GCK69_07530	COG0006	proline dipeptidase activity
GCK69_07540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GCK69_07555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK69_07560	COG0745	RESPONSE REGULATOR receiver
GCK69_07565	COG2205	protein histidine kinase activity
GCK69_07575	COG2190	(PTS) system
GCK69_07585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_07590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GCK69_07595	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GCK69_07610	COG3530	Putative quorum-sensing-regulated virulence factor
GCK69_07640	COG1943	Transposase
GCK69_07680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK69_07695	COG0667	Aldo Keto reductase
GCK69_07720	COG0436	Aminotransferase
GCK69_07730	COG3038	cytochrome b561
GCK69_07760	COG3381	protein complex oligomerization
GCK69_07765	COG3302	dmso reductase anchor subunit
GCK69_07770	COG0437	4 iron, 4 sulfur cluster binding
GCK69_07775	COG0243	molybdopterin cofactor binding
GCK69_07810	COG2951	lytic endotransglycosylase activity
GCK69_07870	COG3121	Chaperone
GCK69_07875	COG3188	usher protein
GCK69_07885	COG3328	transposase activity
GCK69_07890	COG3188	usher protein
GCK69_07950	COG3501	Rhs element vgr protein
GCK69_07980	COG2824	Alkylphosphonate utilization operon protein PhnA
GCK69_07990	COG1704	LemA family
GCK69_08010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK69_08015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK69_08020	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK69_08030	COG1138	Cytochrome C-type biogenesis protein
GCK69_08035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCK69_08040	COG4235	cytochrome complex assembly
GCK69_08040	COG3088	subunit of a heme lyase
GCK69_08045	COG3088	subunit of a heme lyase
GCK69_08045	COG4235	cytochrome complex assembly
GCK69_08060	COG3691	Protein conserved in bacteria
GCK69_08075	COG2062	phosphohistidine phosphatase, SixA
GCK69_08090	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK69_08105	COG0730	response to heat
GCK69_08110	COG3101	peptidyl-lysine hydroxylation
GCK69_08125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK69_08130	COG1794	racemase activity, acting on amino acids and derivatives
GCK69_08145	COG0697	spore germination
GCK69_08160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK69_08170	COG0586	Pfam SNARE associated Golgi protein
GCK69_08180	COG0285	dihydrofolate synthase activity
GCK69_08185	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GCK69_08190	COG1286	toxin biosynthetic process
GCK69_08195	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GCK69_08200	COG0163	prenyltransferase activity
GCK69_08205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK69_08210	COG4215	(ABC) transporter
GCK69_08215	COG4160	amino acid transport
GCK69_08220	COG4598	ABC transporter
GCK69_08225	COG1090	epimerase
GCK69_08240	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GCK69_08245	COG3037	sugar-specific permease SgaT UlaA
GCK69_08260	COG1609	Transcriptional regulator
GCK69_08265	COG0280	phosphate acetyltransferase
GCK69_08265	COG0857	belongs to the CobB CobQ family
GCK69_08285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK69_08290	COG0471	metal ion transport
GCK69_08290	COG0490	domain, Protein
GCK69_08305	COG0436	Aminotransferase
GCK69_08310	COG0583	DNA-binding transcription factor activity
GCK69_08320	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK69_08330	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GCK69_08340	COG1034	ATP synthesis coupled electron transport
GCK69_08355	COG0839	Belongs to the complex I subunit 6 family
GCK69_08365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCK69_08370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK69_08385	COG2731	YhcH YjgK YiaL family protein
GCK69_08390	COG3265	gluconokinase activity
GCK69_08395	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_08405	COG1609	Transcriptional regulator
GCK69_08410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK69_08425	COG0129	dihydroxy-acid dehydratase activity
GCK69_08440	COG4575	ribosome binding
GCK69_08450	COG1169	isochorismate synthase
GCK69_08465	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GCK69_08480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCK69_08525	COG1126	abc transporter atp-binding protein
GCK69_08530	COG0765	amino acid transport
GCK69_08535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK69_08565	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK69_08585	COG1063	alcohol dehydrogenase
GCK69_08590	COG1879	ABC-type sugar transport system periplasmic component
GCK69_08595	COG1129	ABC transporter
GCK69_08600	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_08605	COG1609	Transcriptional regulator
GCK69_08610	COG0583	DNA-binding transcription factor activity
GCK69_08615	COG0473	3-isopropylmalate dehydrogenase activity
GCK69_08625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK69_08630	COG4638	Rieske (2fe-2S)
GCK69_08635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK69_08640	COG2831	hemolysin activation secretion protein
GCK69_08645	COG3210	domain, Protein
GCK69_08665	COG3210	domain, Protein
GCK69_08685	COG3210	domain, Protein
GCK69_08690	COG3210	domain, Protein
GCK69_08700	COG3842	ATPase activity
GCK69_08710	COG1609	Transcriptional regulator
GCK69_08725	COG0395	ABC-type sugar transport system, permease component
GCK69_08730	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCK69_08750	COG0668	transmembrane transport
GCK69_08755	COG1518	maintenance of DNA repeat elements
GCK69_08760	COG1203	CRISPR-associated helicase, Cas3
GCK69_08785	COG0667	Aldo Keto reductase
GCK69_08795	COG0477	Major facilitator Superfamily
GCK69_08805	COG0583	DNA-binding transcription factor activity
GCK69_08810	COG2771	luxR family
GCK69_08815	COG3916	Acyl-homoserine-lactone synthase
GCK69_08835	COG0628	permease
GCK69_08855	COG3328	transposase activity
GCK69_08880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GCK69_08890	COG3328	transposase activity
GCK69_08895	COG1530	ribonuclease E activity
GCK69_08900	COG0564	pseudouridine synthase activity
GCK69_08910	COG1399	metal-binding, possibly nucleic acid-binding protein
GCK69_08915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GCK69_08935	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_08945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK69_08955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK69_08960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCK69_08970	COG0470	DNA polymerase III
GCK69_08975	COG0084	hydrolase, TatD family'
GCK69_08980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK69_08980	COG1263	PTS System
GCK69_08990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCK69_08995	COG0537	adenosine 5'-monophosphoramidase activity
GCK69_09000	COG5633	Lipoprotein
GCK69_09015	COG1472	Belongs to the glycosyl hydrolase 3 family
GCK69_09025	COG1252	NADH dehydrogenase
GCK69_09045	COG3328	transposase activity
GCK69_09055	COG3134	Outer membrane lipoprotein
GCK69_09060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCK69_09065	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK69_09075	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK69_09090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GCK69_09105	COG2850	peptidyl-arginine hydroxylation
GCK69_09115	COG0745	RESPONSE REGULATOR receiver
GCK69_09125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GCK69_09145	COG1187	pseudouridine synthase activity
GCK69_09150	COG0538	isocitrate dehydrogenase activity
GCK69_09165	COG0840	transmembrane signaling receptor activity
GCK69_09170	COG0702	epimerase
GCK69_09175	COG1733	regulation of RNA biosynthetic process
GCK69_09195	COG1522	sequence-specific DNA binding
GCK69_09205	COG3321	synthase
GCK69_09205	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_09205	COG0604	alcohol dehydrogenase
GCK69_09215	COG1278	Cold shock
GCK69_09230	COG1285	pathogenesis
GCK69_09255	COG1360	Flagellar Motor Protein
GCK69_09260	COG2198	Histidine kinase
GCK69_09260	COG0643	Histidine kinase
GCK69_09265	COG0835	chemotaxis
GCK69_09270	COG2271	Major facilitator Superfamily
GCK69_09275	COG0251	oxidation-reduction process
GCK69_09285	COG2964	Protein conserved in bacteria
GCK69_09305	COG0840	transmembrane signaling receptor activity
GCK69_09310	COG0840	transmembrane signaling receptor activity
GCK69_09315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCK69_09325	COG0745	RESPONSE REGULATOR receiver
GCK69_09330	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GCK69_09340	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK69_09350	COG5295	Hep Hag repeat protein
GCK69_09360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK69_09415	COG3121	Chaperone
GCK69_09435	COG3008	intermembrane lipid transfer
GCK69_09440	COG2995	paraquat-inducible protein a
GCK69_09445	COG1956	GAF domain-containing protein
GCK69_09455	COG0793	Belongs to the peptidase S41A family
GCK69_09470	COG3539	Fimbrial protein
GCK69_09475	COG3121	Chaperone
GCK69_09490	COG3121	Chaperone
GCK69_09495	COG2814	Major facilitator Superfamily
GCK69_09500	COG0823	Involved in the tonB-independent uptake of proteins
GCK69_09510	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK69_09520	COG1988	membrane-bound metal-dependent
GCK69_09525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK69_09530	COG1653	transport
GCK69_09535	COG3842	ATPase activity
GCK69_09540	COG0395	ABC-type sugar transport system, permease component
GCK69_09545	COG1175	transmembrane transport
GCK69_09555	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_09565	COG1917	Cupin 2, conserved barrel domain protein
GCK69_09570	COG3328	transposase activity
GCK69_09575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK69_09595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK69_09600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK69_09605	COG1121	(ABC) transporter
GCK69_09610	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCK69_09635	COG4249	Peptidase C14 caspase catalytic subunit p20
GCK69_09665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GCK69_09670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCK69_09670	COG0072	phenylalanine-tRNA ligase activity
GCK69_09675	COG0776	regulation of translation
GCK69_09690	COG0386	Belongs to the glutathione peroxidase family
GCK69_09695	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GCK69_09740	COG0791	NLP P60 protein
GCK69_09765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK69_09765	COG0574	Belongs to the PEP-utilizing enzyme family
GCK69_09775	COG0628	permease
GCK69_09780	COG0247	lactate metabolic process
GCK69_09780	COG0277	FAD linked oxidase domain protein
GCK69_09785	COG2050	protein possibly involved in aromatic compounds catabolism
GCK69_09795	COG0316	Belongs to the HesB IscA family
GCK69_09800	COG0719	Fe-S assembly protein
GCK69_09805	COG0396	ATPase activity
GCK69_09810	COG0719	Fe-S assembly protein
GCK69_09825	COG1388	LysM domain
GCK69_09825	COG1376	ErfK ybiS ycfS ynhG family protein
GCK69_09845	COG4238	major outer membrane lipoprotein
GCK69_09875	COG0307	riboflavin synthase, alpha
GCK69_09880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCK69_09885	COG2814	Major facilitator Superfamily
GCK69_09890	COG0583	DNA-binding transcription factor activity
GCK69_09905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK69_09910	COG0791	NLP P60 protein
GCK69_09920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GCK69_09930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK69_09935	COG0346	lactoylglutathione lyase activity
GCK69_09945	COG1902	pentaerythritol trinitrate reductase activity
GCK69_09950	COG1309	transcriptional regulator
GCK69_09955	COG2194	sulfuric ester hydrolase activity
GCK69_09960	COG3313	Fe-S protein
GCK69_09965	COG4989	oxidoreductase activity
GCK69_09980	COG3133	Outer membrane lipoprotein
GCK69_09990	COG3895	Periplasmic Protein
GCK69_10010	COG0625	glutathione transferase activity
GCK69_10025	COG3104	oligopeptide transport
GCK69_10030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK69_10030	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK69_10035	COG4172	Belongs to the ABC transporter superfamily
GCK69_10045	COG4171	peptide transport system, permease
GCK69_10050	COG4168	peptide transport system, permease
GCK69_10055	COG4166	transmembrane transport
GCK69_10070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GCK69_10075	COG1842	Phage shock protein A
GCK69_10085	COG1983	PspC domain protein
GCK69_10095	COG3106	COG3106 Predicted ATPase
GCK69_10120	COG1943	Transposase
GCK69_10125	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GCK69_10130	COG4948	Mandelate Racemase Muconate Lactonizing
GCK69_10135	COG2866	Carboxypeptidase
GCK69_10140	COG4166	transmembrane transport
GCK69_10160	COG0657	acetylesterase activity
GCK69_10160	COG2755	lipolytic protein G-D-S-L family
GCK69_10170	COG1013	pyruvate-flavodoxin oxidoreductase activity
GCK69_10170	COG0674	pyruvate-flavodoxin oxidoreductase activity
GCK69_10170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK69_10170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GCK69_10180	COG1285	pathogenesis
GCK69_10185	COG3042	response to heat
GCK69_10190	COG3187	Heat shock protein
GCK69_10195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK69_10200	COG2911	Protein conserved in bacteria
GCK69_10210	COG3784	Protein of unknown function (DUF1318)
GCK69_10215	COG0246	Mannitol dehydrogenase
GCK69_10220	COG2390	Transcriptional regulator
GCK69_10230	COG1643	Atp-dependent helicase
GCK69_10245	COG3591	Belongs to the peptidase S1B family
GCK69_10260	COG3038	cytochrome b561
GCK69_10285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GCK69_10290	COG2205	protein histidine kinase activity
GCK69_10295	COG0745	RESPONSE REGULATOR receiver
GCK69_10305	COG0531	amino acid
GCK69_10320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GCK69_10325	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GCK69_10330	COG0589	response to stress
GCK69_10335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCK69_10340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK69_10355	COG1011	Hydrolase
GCK69_10360	COG0440	acetolactate synthase activity
GCK69_10365	COG0028	Belongs to the TPP enzyme family
GCK69_10395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK69_10405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK69_10410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK69_10425	COG1609	Transcriptional regulator
GCK69_10435	COG0038	chloride channel
GCK69_10440	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK69_10445	COG1940	carbohydrate kinase activity
GCK69_10450	COG0583	DNA-binding transcription factor activity
GCK69_10455	COG2814	Major facilitator Superfamily
GCK69_10465	COG0114	fumarate hydratase activity
GCK69_10475	COG5339	Protein conserved in bacteria
GCK69_10485	COG0385	Bile acid
GCK69_10490	COG0673	inositol 2-dehydrogenase activity
GCK69_10500	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_10510	COG1879	ABC-type sugar transport system periplasmic component
GCK69_10525	COG2274	protein secretion by the type I secretion system
GCK69_10530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK69_10565	COG2207	Transcriptional regulator
GCK69_10565	COG3708	Transcriptional regulator
GCK69_10570	COG4658	electron transport chain
GCK69_10575	COG4659	FMN binding
GCK69_10585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCK69_10590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK69_10595	COG2271	Major facilitator Superfamily
GCK69_10605	COG1966	Carbon starvation protein
GCK69_10610	COG2879	small protein
GCK69_10615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCK69_10635	COG0023	Translation Initiation Factor
GCK69_10650	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GCK69_10655	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GCK69_10660	COG0671	phosphoesterase, PA-phosphatase related
GCK69_10665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GCK69_10670	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCK69_10680	COG0583	DNA-binding transcription factor activity
GCK69_10685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK69_10700	COG0616	signal peptide processing
GCK69_10705	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_10715	COG1187	pseudouridine synthase activity
GCK69_10720	COG0009	L-threonylcarbamoyladenylate synthase
GCK69_10745	COG0512	Glutamine amidotransferase of anthranilate synthase
GCK69_10755	COG0135	phosphoribosylanthranilate isomerase activity
GCK69_10755	COG0134	indole-3-glycerol-phosphate synthase activity
GCK69_10775	COG3047	cAMP biosynthetic process
GCK69_10810	COG1607	acyl-coa hydrolase
GCK69_10815	COG3328	transposase activity
GCK69_10820	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GCK69_10825	COG2350	Protein conserved in bacteria
GCK69_10865	COG4608	Belongs to the ABC transporter superfamily
GCK69_10870	COG0444	Belongs to the ABC transporter superfamily
GCK69_10875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK69_10880	COG0601	transmembrane transport
GCK69_10890	COG2095	MarC family integral membrane protein
GCK69_10900	COG1454	alcohol dehydrogenase
GCK69_10900	COG1012	belongs to the aldehyde dehydrogenase family
GCK69_10920	COG1435	thymidine kinase activity
GCK69_10935	COG0745	RESPONSE REGULATOR receiver
GCK69_10950	COG0788	formyltetrahydrofolate deformylase activity
GCK69_10955	COG3328	transposase activity
GCK69_10975	COG0583	DNA-binding transcription factor activity
GCK69_10980	COG0708	Exodeoxyribonuclease III
GCK69_10985	COG0494	nUDIX hydrolase
GCK69_10995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK69_11000	COG0709	Synthesizes selenophosphate from selenide and ATP
GCK69_11005	COG0778	Nitroreductase
GCK69_11010	COG0616	signal peptide processing
GCK69_11015	COG0252	asparaginase activity
GCK69_11020	COG1335	isochorismatase
GCK69_11025	COG3139	Protein of unknown function (DUF1315)
GCK69_11045	COG3713	MltA-interacting MipA family protein
GCK69_11055	COG2766	serine protein kinase
GCK69_11070	COG0583	DNA-binding transcription factor activity
GCK69_11080	COG2814	Major facilitator Superfamily
GCK69_11090	COG2719	SpoVR family
GCK69_11125	COG1104	cysteine desulfurase activity
GCK69_11135	COG3328	transposase activity
GCK69_11305	COG3328	transposase activity
GCK69_11400	COG0582	viral genome integration into host DNA
GCK69_11410	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCK69_11415	COG2951	lytic endotransglycosylase activity
GCK69_11430	COG2894	cell division
GCK69_11435	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GCK69_11440	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GCK69_11445	COG0318	PFAM AMP-dependent synthetase and ligase
GCK69_11455	COG3065	identical protein binding
GCK69_11465	COG1199	ATP-dependent helicase activity
GCK69_11470	COG0251	oxidation-reduction process
GCK69_11485	COG0800	Aldolase
GCK69_11495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCK69_11500	COG1737	Transcriptional regulator
GCK69_11505	COG0469	pyruvate kinase activity
GCK69_11515	COG1560	Kdo2-lipid A biosynthetic process
GCK69_11520	COG0739	heme binding
GCK69_11525	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GCK69_11535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK69_11565	COG0494	nUDIX hydrolase
GCK69_11575	COG1801	Protein of unknown function DUF72
GCK69_11580	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GCK69_11600	COG3102	Protein conserved in bacteria
GCK69_11620	COG0728	peptidoglycan biosynthetic process
GCK69_11630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK69_11645	COG3381	protein complex oligomerization
GCK69_11660	COG1940	carbohydrate kinase activity
GCK69_11665	COG0584	glycerophosphoryl diester phosphodiesterase
GCK69_11685	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK69_11690	COG3833	ABC-type maltose transport systems, permease component
GCK69_11715	COG0659	secondary active sulfate transmembrane transporter activity
GCK69_11725	COG2912	Transglutaminase-like superfamily
GCK69_11730	COG3094	Invasion gene expression up-regulator, SirB
GCK69_11735	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK69_11760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GCK69_11775	COG0012	GTP binding
GCK69_11830	COG5002	protein histidine kinase activity
GCK69_11870	COG0500	methyltransferase
GCK69_11895	COG3328	transposase activity
GCK69_11940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK69_11960	COG0402	S-adenosylhomocysteine deaminase activity
GCK69_12025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCK69_12035	COG3850	Histidine kinase
GCK69_12040	COG0387	Pfam Sodium calcium exchanger
GCK69_12045	COG1702	phosphate starvation-inducible protein PhoH
GCK69_12060	COG3658	cytochrome
GCK69_12065	COG1215	transferase activity, transferring glycosyl groups
GCK69_12070	COG0726	polysaccharide deacetylase
GCK69_12070	COG1649	PFAM Uncharacterised BCR, COG1649
GCK69_12075	COG0457	Tetratricopeptide repeat
GCK69_12080	COG0006	proline dipeptidase activity
GCK69_12100	COG0577	efflux transmembrane transporter activity
GCK69_12100	COG1136	(ABC) transporter
GCK69_12110	COG1136	(ABC) transporter
GCK69_12110	COG0577	efflux transmembrane transporter activity
GCK69_12125	COG0672	)-iron permease
GCK69_12135	COG2066	Belongs to the glutaminase family
GCK69_12145	COG1349	DNA-binding transcription factor activity
GCK69_12155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCK69_12160	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK69_12200	COG2030	dehydratase
GCK69_12205	COG0427	acetyl-CoA hydrolase
GCK69_12215	COG2205	protein histidine kinase activity
GCK69_12215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK69_12230	COG3188	usher protein
GCK69_12240	COG3121	Chaperone
GCK69_12250	COG0582	viral genome integration into host DNA
GCK69_12255	COG1169	isochorismate synthase
GCK69_12260	COG2814	Major facilitator Superfamily
GCK69_12265	COG1132	(ABC) transporter
GCK69_12280	COG3433	isochorismatase activity
GCK69_12280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK69_12280	COG2226	methyltransferase
GCK69_12300	COG1021	2,3-dihydroxybenzoate-AMP ligase
GCK69_12305	COG4771	TonB-dependent receptor
GCK69_12385	COG0395	ABC-type sugar transport system, permease component
GCK69_12390	COG1175	transmembrane transport
GCK69_12400	COG0673	inositol 2-dehydrogenase activity
GCK69_12555	COG2197	response regulator
GCK69_12565	COG3136	membrane protein required for alginate biosynthesis
GCK69_12590	COG1113	amino acid transport
GCK69_12605	COG2837	iron assimilation
GCK69_12630	COG0506	proline dehydrogenase activity
GCK69_12630	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK69_12630	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK69_12660	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GCK69_12670	COG1191	sigma factor activity
GCK69_12705	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GCK69_12710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCK69_12715	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GCK69_12735	COG1677	Flagellar hook-basal body complex protein FliE
GCK69_12745	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCK69_12755	COG1157	protein secretion by the type III secretion system
GCK69_12760	COG2882	bacterial-type flagellum organization
GCK69_12770	COG1580	Controls the rotational direction of flagella during chemotaxis
GCK69_12795	COG1987	bacterial-type flagellum assembly
GCK69_12815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK69_12820	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_12825	COG1129	ABC transporter
GCK69_12835	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_12840	COG3347	Dehydrogenase
GCK69_12840	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_12845	COG2390	Transcriptional regulator
GCK69_12855	COG1256	bacterial-type flagellum assembly
GCK69_12875	COG4786	Flagellar basal body rod
GCK69_12885	COG1749	Flagellar hook protein flgE
GCK69_12890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK69_12895	COG1558	bacterial-type flagellum-dependent cell motility
GCK69_12900	COG1815	bacterial-type flagellum-dependent cell motility
GCK69_12910	COG2747	anti-sigma28 factor FlgM
GCK69_12915	COG3418	PFAM FlgN family protein
GCK69_12940	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK69_12945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK69_12975	COG2372	response to copper ion
GCK69_12980	COG1528	Iron-storage protein
GCK69_12995	COG1770	oligopeptidase
GCK69_13010	COG3141	response to X-ray
GCK69_13015	COG0513	Belongs to the DEAD box helicase family
GCK69_13040	COG1760	l-serine dehydratase
GCK69_13045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCK69_13050	COG2368	4-hydroxyphenylacetate
GCK69_13065	COG3971	2-oxopent-4-enoate hydratase activity
GCK69_13075	COG3384	dioxygenase
GCK69_13080	COG1012	belongs to the aldehyde dehydrogenase family
GCK69_13095	COG1846	Transcriptional regulator
GCK69_13105	COG1253	flavin adenine dinucleotide binding
GCK69_13110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK69_13110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_13115	COG3715	PTS system
GCK69_13120	COG3716	PTS system mannose fructose sorbose family IID component
GCK69_13140	COG3447	MASE1 domain protein
GCK69_13140	COG5001	Diguanylate cyclase
GCK69_13140	COG5002	protein histidine kinase activity
GCK69_13150	COG2226	methyltransferase
GCK69_13160	COG1278	Cold shock
GCK69_13180	COG1113	amino acid transport
GCK69_13220	COG2207	Transcriptional regulator
GCK69_13235	COG1132	(ABC) transporter
GCK69_13290	COG3328	transposase activity
GCK69_13295	COG2223	nitrite transmembrane transporter activity
GCK69_13320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCK69_13345	COG3122	Protein conserved in bacteria
GCK69_13365	COG0534	Mate efflux family protein
GCK69_13385	COG4948	Mandelate Racemase Muconate Lactonizing
GCK69_13395	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_13400	COG3011	Protein conserved in bacteria
GCK69_13405	COG2271	Major facilitator Superfamily
GCK69_13410	COG1388	LysM domain
GCK69_13410	COG1470	cell adhesion involved in biofilm formation
GCK69_13415	COG3328	transposase activity
GCK69_13430	COG2925	Exonuclease
GCK69_13440	COG0531	amino acid
GCK69_13450	COG0371	Dehydrogenase
GCK69_13455	COG1129	ABC transporter
GCK69_13460	COG1129	ABC transporter
GCK69_13465	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_13470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK69_13485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCK69_13495	COG0131	Imidazoleglycerol-phosphate dehydratase
GCK69_13495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK69_13500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GCK69_13515	COG0140	phosphoribosyl-ATP diphosphatase activity
GCK69_13515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GCK69_13525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK69_13530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK69_13545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK69_13550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK69_13555	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK69_13560	COG1120	ATPase activity
GCK69_13575	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GCK69_13580	COG0076	glutamate decarboxylase activity
GCK69_13585	COG4114	ferric iron reductase
GCK69_13590	COG1253	flavin adenine dinucleotide binding
GCK69_13595	COG2982	Protein involved in outer membrane biogenesis
GCK69_13610	COG0489	protein tyrosine kinase activity
GCK69_13620	COG1943	Transposase
GCK69_13640	COG2814	Major facilitator Superfamily
GCK69_13650	COG1346	cytolysis
GCK69_13665	COG2949	membrane
GCK69_13670	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCK69_13685	COG2311	Membrane
GCK69_13695	COG0477	Major facilitator Superfamily
GCK69_13700	COG0583	DNA-binding transcription factor activity
GCK69_13730	COG1136	(ABC) transporter
GCK69_13740	COG0303	'Molybdopterin
GCK69_13750	COG3328	transposase activity
GCK69_13760	COG0488	(ABC) transporter
GCK69_13885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCK69_13890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCK69_13900	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_13905	COG1024	Enoyl-CoA hydratase
GCK69_13915	COG3425	synthase
GCK69_13920	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_13925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK69_13930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCK69_13940	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_13965	COG2920	part of a sulfur-relay system
GCK69_13985	COG1832	CoA-binding protein
GCK69_13990	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GCK69_14000	COG0210	DNA helicase
GCK69_14005	COG3304	Inner membrane component domain
GCK69_14010	COG1289	transmembrane transporter activity
GCK69_14015	COG3070	regulator of competence-specific genes
GCK69_14025	COG2885	chlorophyll binding
GCK69_14025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK69_14030	COG1943	Transposase
GCK69_14040	COG1067	ATP-dependent peptidase activity
GCK69_14075	COG1943	Transposase
GCK69_14080	COG3130	regulation of translation
GCK69_14090	COG3009	Protein conserved in bacteria
GCK69_14100	COG3008	intermembrane lipid transfer
GCK69_14100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK69_14105	COG2995	paraquat-inducible protein a
GCK69_14110	COG0488	(ABC) transporter
GCK69_14120	COG0633	Ferredoxin
GCK69_14120	COG3217	Mosc domain protein beta barrel domain protein
GCK69_14135	COG0308	aminopeptidase N
GCK69_14155	COG1448	Aminotransferase
GCK69_14165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK69_14170	COG3108	Peptidase M15
GCK69_14175	COG2989	Protein conserved in bacteria
GCK69_14180	COG1943	Transposase
GCK69_14190	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GCK69_14195	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GCK69_14200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCK69_14215	COG3173	Aminoglycoside phosphotransferase
GCK69_14230	COG2835	tetraacyldisaccharide 4'-kinase activity
GCK69_14235	COG1278	Cold shock
GCK69_14245	COG5383	Protein conserved in bacteria
GCK69_14260	COG0658	competence protein
GCK69_14260	COG2333	competence protein COMEC
GCK69_14275	COG0539	negative regulation of cytoplasmic translation
GCK69_14300	COG5295	Hep Hag repeat protein
GCK69_14300	COG5295	Hep Hag repeat protein
GCK69_14305	COG0252	asparaginase activity
GCK69_14310	COG1944	ATP diphosphatase activity
GCK69_14315	COG2116	formate transmembrane transporter activity
GCK69_14320	COG1882	Formate acetyltransferase
GCK69_14330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCK69_14335	COG2814	Major facilitator Superfamily
GCK69_14345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCK69_14355	COG1674	ftsk spoiiie
GCK69_14355	COG3107	peptidoglycan biosynthetic process
GCK69_14365	COG0492	ferredoxin-NADP+ reductase activity
GCK69_14375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCK69_14385	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCK69_14400	COG0542	response to heat
GCK69_14415	COG1278	Cold shock
GCK69_14425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK69_14430	COG2990	Protein conserved in bacteria
GCK69_14435	COG3593	DNA synthesis involved in DNA repair
GCK69_14440	COG2431	L-lysine efflux transmembrane transporter activity
GCK69_14450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK69_14455	COG0028	Belongs to the TPP enzyme family
GCK69_14465	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCK69_14470	COG0702	epimerase
GCK69_14475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK69_14485	COG1605	Chorismate mutase
GCK69_14490	COG1126	abc transporter atp-binding protein
GCK69_14495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK69_14500	COG4215	(ABC) transporter
GCK69_14505	COG4160	amino acid transport
GCK69_14525	COG1120	ATPase activity
GCK69_14530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK69_14535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK69_14560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK69_14575	COG1177	transmembrane transport
GCK69_14580	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK69_14585	COG3842	ATPase activity
GCK69_14590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCK69_14610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK69_14615	COG0569	domain protein
GCK69_14615	COG2985	domain, Protein
GCK69_14625	COG0671	phosphoesterase, PA-phosphatase related
GCK69_14630	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK69_14635	COG1349	DNA-binding transcription factor activity
GCK69_14640	COG0814	amino acid
GCK69_14645	COG1686	Belongs to the peptidase S11 family
GCK69_14650	COG2011	ABC-type metal ion transport system permease component
GCK69_14675	COG0625	glutathione transferase activity
GCK69_14685	COG4771	TonB-dependent receptor
GCK69_14695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK69_14705	COG0833	amino acid
GCK69_14710	COG0583	DNA-binding transcription factor activity
GCK69_14715	COG2855	membrane
GCK69_14725	COG3188	usher protein
GCK69_14730	COG3121	Chaperone
GCK69_14745	COG3710	Transcriptional regulator
GCK69_14750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK69_14750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK69_14750	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GCK69_14755	COG1105	Belongs to the carbohydrate kinase PfkB family
GCK69_14765	COG0494	nUDIX hydrolase
GCK69_14770	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_14775	COG1129	ABC transporter
GCK69_14785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCK69_14810	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_14830	COG1312	Catalyzes the dehydration of D-mannonate
GCK69_14835	COG0246	Mannitol dehydrogenase
GCK69_14840	COG2186	Transcriptional regulator
GCK69_14850	COG0523	cobalamin synthesis protein
GCK69_14855	COG0671	phosphoesterase, PA-phosphatase related
GCK69_14860	COG0791	NLP P60 protein
GCK69_14865	COG2200	EAL domain
GCK69_14870	COG4166	transmembrane transport
GCK69_14875	COG4174	ABC transporter (Permease)
GCK69_14880	COG4239	(ABC) transporter, permease
GCK69_14885	COG4172	Belongs to the ABC transporter superfamily
GCK69_14895	COG2814	Major facilitator Superfamily
GCK69_14900	COG1187	pseudouridine synthase activity
GCK69_14905	COG1061	Type III restriction enzyme res subunit
GCK69_14920	COG1943	Transposase
GCK69_14930	COG3082	Protein of unknown function (DUF1414)
GCK69_14935	COG3083	sulfuric ester hydrolase activity
GCK69_14955	COG3157	Type VI secretion system effector, Hcp
GCK69_14970	COG2723	6-phospho-beta-galactosidase activity
GCK69_14975	COG1737	Transcriptional regulator
GCK69_14995	COG3299	homolog of phage Mu protein gp47
GCK69_15035	COG4386	tail sheath protein
GCK69_15055	COG3622	Belongs to the hyi family
GCK69_15060	COG1349	DNA-binding transcription factor activity
GCK69_15065	COG0235	Class ii aldolase
GCK69_15070	COG3395	kinase activity
GCK69_15115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCK69_15140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCK69_15145	COG2223	nitrite transmembrane transporter activity
GCK69_15150	COG2198	Histidine kinase
GCK69_15150	COG0642	Histidine kinase
GCK69_15155	COG2198	Histidine kinase
GCK69_15155	COG0642	Histidine kinase
GCK69_15165	COG2205	protein histidine kinase activity
GCK69_15165	COG0784	Response regulator, receiver
GCK69_15190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK69_15205	COG0814	amino acid
GCK69_15235	COG0697	spore germination
GCK69_15245	COG1982	Orn Lys Arg decarboxylase major
GCK69_15250	COG0531	amino acid
GCK69_15255	COG1174	glycine betaine transport
GCK69_15260	COG1125	glycine betaine transport
GCK69_15265	COG1174	glycine betaine transport
GCK69_15275	COG2897	thiosulfate sulfurtransferase activity
GCK69_15295	COG0410	ABC transporter
GCK69_15300	COG1122	ATPase activity
GCK69_15320	COG4807	Protein conserved in bacteria
GCK69_15335	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GCK69_15345	COG2261	transglycosylase associated protein
GCK69_15355	COG1403	HNH endonuclease
GCK69_15365	COG0277	FAD linked oxidase domain protein
GCK69_15370	COG1686	Belongs to the peptidase S11 family
GCK69_15380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK69_15405	COG3328	transposase activity
GCK69_15440	COG0513	Belongs to the DEAD box helicase family
GCK69_15445	COG1309	transcriptional regulator
GCK69_15455	COG1131	(ABC) transporter
GCK69_15460	COG0842	Transport permease protein
GCK69_15465	COG0842	Transport permease protein
GCK69_15485	COG1902	pentaerythritol trinitrate reductase activity
GCK69_15520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GCK69_15530	COG0583	DNA-binding transcription factor activity
GCK69_15535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK69_15555	COG1943	Transposase
GCK69_15560	COG0670	Belongs to the BI1 family
GCK69_15565	COG0314	molybdopterin synthase activity
GCK69_15570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GCK69_15580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GCK69_15585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GCK69_15590	COG4628	conserved protein (DUF2132)
GCK69_15595	COG0556	nucleotide-excision repair
GCK69_15605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK69_15610	COG2226	methyltransferase
GCK69_15635	COG0561	phosphatase activity
GCK69_15645	COG4149	molybdate abc transporter
GCK69_15650	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCK69_15660	COG2005	Transcriptional regulator
GCK69_15660	COG3585	molybdate ion transport
GCK69_15670	COG1119	ATPase activity
GCK69_15680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCK69_15685	COG1085	galactose-1-phosphate uridylyltransferase
GCK69_15700	COG2017	converts alpha-aldose to the beta-anomer
GCK69_15715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK69_15720	COG1230	cation diffusion facilitator family transporter
GCK69_15750	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GCK69_15755	COG2885	chlorophyll binding
GCK69_15765	COG3064	Membrane
GCK69_15765	COG3064	Membrane
GCK69_15770	COG0848	biopolymer transport protein
GCK69_15775	COG0811	peptide transport
GCK69_15780	COG0824	Thioesterase
GCK69_15785	COG3790	cyd operon protein YbgE
GCK69_15790	COG4890	Cyd operon protein YbgT
GCK69_15795	COG1294	oxidase, subunit
GCK69_15800	COG1271	oxidase subunit
GCK69_15805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCK69_15815	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK69_15820	COG0567	Dehydrogenase, E1 component
GCK69_15830	COG1053	succinate dehydrogenase
GCK69_15835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GCK69_15840	COG2009	succinate dehydrogenase
GCK69_15855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GCK69_15860	COG0497	DNA recombination
GCK69_15865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK69_15875	COG2867	negative regulation of translational initiation
GCK69_15900	COG0582	viral genome integration into host DNA
GCK69_15960	COG3657	addiction module killer protein
GCK69_15985	COG1953	Uracil, thiamine, allantoin
GCK69_15995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK69_16005	COG2226	methyltransferase
GCK69_16015	COG0741	lytic transglycosylase activity
GCK69_16015	COG1388	LysM domain
GCK69_16030	COG0656	L-ascorbic acid biosynthetic process
GCK69_16065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK69_16075	COG2011	ABC-type metal ion transport system permease component
GCK69_16080	COG1464	Belongs to the NlpA lipoprotein family
GCK69_16090	COG1720	tRNA m6t6A37 methyltransferase activity
GCK69_16100	COG3015	lipoprotein NlpE involved in copper resistance
GCK69_16110	COG4681	YaeQ
GCK69_16120	COG4568	rho-dependent transcription termination
GCK69_16130	COG0037	tRNA processing
GCK69_16135	COG0346	lactoylglutathione lyase activity
GCK69_16145	COG0587	DNA-directed DNA polymerase activity
GCK69_16155	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCK69_16175	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GCK69_16185	COG0750	zinc metalloprotease
GCK69_16190	COG0575	Belongs to the CDS family
GCK69_16195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GCK69_16230	COG0024	Methionine aminopeptidase
GCK69_16255	COG0564	pseudouridine synthase activity
GCK69_16260	COG3098	single-species biofilm formation
GCK69_16265	COG1943	Transposase
GCK69_16280	COG1611	Belongs to the LOG family
GCK69_16290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK69_16300	COG2363	Small membrane protein
GCK69_16305	COG0583	DNA-binding transcription factor activity
GCK69_16315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCK69_16320	COG2166	iron-sulfur cluster assembly
GCK69_16325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCK69_16330	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GCK69_16345	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK69_16355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GCK69_16360	COG1074	ATP-dependent DNA helicase activity
GCK69_16370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GCK69_16485	COG1609	Transcriptional regulator
GCK69_16490	COG0019	diaminopimelate decarboxylase activity
GCK69_16495	COG0583	DNA-binding transcription factor activity
GCK69_16500	COG2814	Major facilitator Superfamily
GCK69_16505	COG0583	DNA-binding transcription factor activity
GCK69_16520	COG0840	transmembrane signaling receptor activity
GCK69_16565	COG2165	general secretion pathway protein
GCK69_16615	COG0288	reversible hydration of carbon dioxide
GCK69_16655	COG1943	Transposase
GCK69_16660	COG3119	arylsulfatase activity
GCK69_16665	COG1349	DNA-binding transcription factor activity
GCK69_16675	COG2222	sugar isomerase
GCK69_16680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK69_16685	COG3715	PTS system
GCK69_16690	COG3716	PTS system mannose fructose sorbose family IID component
GCK69_16695	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_16705	COG1028	Short-chain dehydrogenase reductase Sdr
GCK69_16715	COG0641	radical SAM
GCK69_16720	COG3119	arylsulfatase activity
GCK69_16730	COG0191	fructose-bisphosphate aldolase activity
GCK69_16750	COG2271	Major facilitator Superfamily
GCK69_16770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK69_16770	COG1263	PTS System
GCK69_16775	COG1874	Beta-galactosidase
GCK69_16780	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GCK69_16785	COG3833	ABC-type maltose transport systems, permease component
GCK69_16790	COG1175	transmembrane transport
GCK69_16795	COG2182	Extracellular solute-binding protein
GCK69_16805	COG1129	ABC transporter
GCK69_16810	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_16815	COG1879	ABC-type sugar transport system periplasmic component
GCK69_16825	COG0791	NLP P60 protein
GCK69_16830	COG1695	Transcriptional regulator
GCK69_16920	COG2944	sequence-specific DNA binding
GCK69_16945	COG0582	viral genome integration into host DNA
GCK69_16965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GCK69_16970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK69_16975	COG4974	Belongs to the 'phage' integrase family
GCK69_16980	COG0716	FMN binding
GCK69_16985	COG4452	Inner membrane protein CreD
GCK69_16990	COG2205	protein histidine kinase activity
GCK69_16995	COG0745	RESPONSE REGULATOR receiver
GCK69_17005	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GCK69_17020	COG1272	protein, Hemolysin III
GCK69_17065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK69_17070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK69_17075	COG0006	proline dipeptidase activity
GCK69_17095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCK69_17100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCK69_17105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCK69_17135	COG0191	fructose-bisphosphate aldolase activity
GCK69_17155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCK69_17160	COG0501	Belongs to the peptidase M48B family
GCK69_17175	COG1943	Transposase
GCK69_17180	COG1166	arginine decarboxylase activity
GCK69_17195	COG2356	endonuclease I
GCK69_17200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCK69_17205	COG0189	ligase activity
GCK69_17220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK69_17230	COG2805	Type II/IV secretion system protein
GCK69_17235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCK69_17240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCK69_17250	COG0762	integral membrane protein
GCK69_17260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GCK69_17265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK69_17270	COG1073	alpha beta
GCK69_17270	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GCK69_17270	COG3064	Membrane
GCK69_17280	COG2066	Belongs to the glutaminase family
GCK69_17285	COG3171	Protein conserved in bacteria
GCK69_17295	COG1194	a g-specific adenine glycosylase
GCK69_17315	COG4774	siderophore transport
GCK69_17320	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_17325	COG1129	ABC transporter
GCK69_17330	COG1879	ABC-type sugar transport system periplasmic component
GCK69_17335	COG1982	Orn Lys Arg decarboxylase major
GCK69_17465	COG3916	Acyl-homoserine-lactone synthase
GCK69_17470	COG2771	luxR family
GCK69_17520	COG2211	Major facilitator Superfamily
GCK69_17540	COG0471	metal ion transport
GCK69_17560	COG3209	COG3209 Rhs family protein
GCK69_17570	COG3501	Rhs element vgr protein
GCK69_17585	COG2610	gluconate transmembrane transporter activity
GCK69_17600	COG1132	(ABC) transporter
GCK69_17635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK69_17640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK69_17640	COG3433	isochorismatase activity
GCK69_17640	COG2226	methyltransferase
GCK69_17660	COG4771	TonB-dependent receptor
GCK69_17665	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK69_17675	COG3328	transposase activity
GCK69_17730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GCK69_17735	COG1191	sigma factor activity
GCK69_17760	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GCK69_17780	COG3710	Transcriptional regulator
GCK69_17800	COG1256	bacterial-type flagellum assembly
GCK69_17810	COG1706	bacterial-type flagellum-dependent cell motility
GCK69_17815	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GCK69_17820	COG4786	Flagellar basal body rod
GCK69_17825	COG4787	bacterial-type flagellum-dependent cell motility
GCK69_17830	COG1749	Flagellar hook protein flgE
GCK69_17835	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK69_17840	COG1558	bacterial-type flagellum-dependent cell motility
GCK69_17845	COG1815	bacterial-type flagellum-dependent cell motility
GCK69_17850	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GCK69_17895	COG2204	response regulator
GCK69_17915	COG1987	bacterial-type flagellum assembly
GCK69_17920	COG1684	flagellar biosynthetic protein fliR
GCK69_17925	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK69_17945	COG4592	Periplasmic binding protein
GCK69_17980	COG4964	Belongs to the GSP D family
GCK69_17985	COG4964	Belongs to the GSP D family
GCK69_18040	COG0848	biopolymer transport protein
GCK69_18045	COG0811	peptide transport
GCK69_18050	COG0626	cystathionine gamma-synthase activity
GCK69_18055	COG0586	Pfam SNARE associated Golgi protein
GCK69_18060	COG2207	Transcriptional regulator
GCK69_18065	COG1979	alcohol dehydrogenase
GCK69_18075	COG0656	L-ascorbic acid biosynthetic process
GCK69_18090	COG2132	Multicopper oxidase
GCK69_18100	COG0204	Acyl-transferase
GCK69_18105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GCK69_18115	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK69_18120	COG0583	DNA-binding transcription factor activity
GCK69_18125	COG0187	DNA topoisomerase II activity
GCK69_18130	COG3150	esterase
GCK69_18135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCK69_18140	COG3151	Protein conserved in bacteria
GCK69_18145	COG0494	nUDIX hydrolase
GCK69_18150	COG1538	Outer membrane efflux protein
GCK69_18165	COG0754	glutathionylspermidine amidase activity
GCK69_18170	COG3384	dioxygenase
GCK69_18190	COG0531	amino acid
GCK69_18205	COG3025	triphosphatase activity
GCK69_18210	COG4991	sh3 domain protein
GCK69_18225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GCK69_18250	COG0358	DNA primase activity
GCK69_18255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCK69_18335	COG0251	oxidation-reduction process
GCK69_18380	COG1289	transmembrane transporter activity
GCK69_18400	COG0395	ABC-type sugar transport system, permease component
GCK69_18410	COG1653	transport
GCK69_18415	COG1609	Transcriptional regulator
GCK69_18420	COG3459	Glycosyltransferase 36 associated
GCK69_18425	COG3842	ATPase activity
GCK69_18445	COG3210	domain, Protein
GCK69_18450	COG3210	domain, Protein
GCK69_18475	COG3210	domain, Protein
GCK69_18480	COG2831	hemolysin activation secretion protein
GCK69_18485	COG4245	von Willebrand factor, type A
GCK69_18500	COG4245	von Willebrand factor, type A
GCK69_18520	COG3247	response to pH
GCK69_18525	COG1902	pentaerythritol trinitrate reductase activity
GCK69_18525	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCK69_18540	COG1451	nucleotide metabolic process
GCK69_18545	COG0673	inositol 2-dehydrogenase activity
GCK69_18555	COG1943	Transposase
GCK69_18565	COG2721	sulfolactate sulfo-lyase activity
GCK69_18570	COG0246	Mannitol dehydrogenase
GCK69_18580	COG2271	Major facilitator Superfamily
GCK69_18595	COG0586	Pfam SNARE associated Golgi protein
GCK69_18615	COG4575	ribosome binding
GCK69_18620	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GCK69_18630	COG2259	Doxx family
GCK69_18650	COG0494	nUDIX hydrolase
GCK69_18680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCK69_18685	COG0849	cell division
GCK69_18690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GCK69_18710	COG0772	Belongs to the SEDS family
GCK69_18725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GCK69_18730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCK69_18735	COG0768	penicillin binding
GCK69_18740	COG3116	cell division
GCK69_18765	COG1609	Transcriptional regulator
GCK69_18775	COG1943	Transposase
GCK69_18785	COG0028	Belongs to the TPP enzyme family
GCK69_18795	COG1022	Amp-dependent synthetase and ligase
GCK69_18815	COG1943	Transposase
GCK69_18825	COG0473	3-isopropylmalate dehydrogenase activity
GCK69_18840	COG2814	Major facilitator Superfamily
GCK69_18855	COG4143	(ABC) transporter
GCK69_18860	COG1178	ABC-type Fe3 transport system permease component
GCK69_18870	COG0586	Pfam SNARE associated Golgi protein
GCK69_18875	COG0417	DNA replication proofreading
GCK69_18895	COG2885	chlorophyll binding
GCK69_18895	COG3047	cAMP biosynthetic process
GCK69_18930	COG3501	Rhs element vgr protein
GCK69_18980	COG0564	pseudouridine synthase activity
GCK69_18985	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GCK69_18995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK69_19000	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GCK69_19030	COG1943	Transposase
GCK69_19035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCK69_19045	COG2966	Psort location CytoplasmicMembrane, score
GCK69_19050	COG1280	lysine exporter protein (LysE YggA)
GCK69_19055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GCK69_19060	COG0505	Belongs to the CarA family
GCK69_19080	COG1047	Peptidyl-prolyl cis-trans
GCK69_19095	COG0196	riboflavin kinase activity
GCK69_19115	COG0583	DNA-binding transcription factor activity
GCK69_19135	COG1584	GPR1 FUN34 yaaH family protein
GCK69_19150	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCK69_19190	COG0745	RESPONSE REGULATOR receiver
GCK69_19195	COG3045	CreA protein
GCK69_19205	COG2207	Transcriptional regulator
GCK69_19205	COG3708	Transcriptional regulator
GCK69_19220	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GCK69_19225	COG0741	lytic transglycosylase activity
GCK69_19240	COG2199	diguanylate cyclase activity
GCK69_19245	COG2885	chlorophyll binding
GCK69_19270	COG0560	Phosphoserine phosphatase
GCK69_19275	COG3726	membrane protein affecting hemolysin expression
GCK69_19295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK69_19300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK69_19305	COG0084	hydrolase, TatD family'
GCK69_19310	COG4667	esterase of the alpha-beta hydrolase superfamily
GCK69_19320	COG2823	Periplasmic or secreted lipoprotein
GCK69_19330	COG0456	acetyltransferase
GCK69_19335	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GCK69_19355	COG3706	GGDEF domain
GCK69_19380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK69_19385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK69_19400	COG0859	PFAM glycosyl transferase family 9
GCK69_19455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_19455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK69_19455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK69_19460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK69_19465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK69_19470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK69_19475	COG2207	Transcriptional regulator
GCK69_19485	COG4269	membrane
GCK69_19545	COG1401	restriction endodeoxyribonuclease activity
GCK69_19610	COG0151	Belongs to the GarS family
GCK69_19625	COG3068	Protein conserved in bacteria
GCK69_19630	COG1515	deoxyribonuclease V activity
GCK69_19655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GCK69_19665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCK69_19690	COG1943	Transposase
GCK69_19725	COG0250	Participates in transcription elongation, termination and antitermination
GCK69_19730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK69_19785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCK69_19820	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GCK69_19825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GCK69_19840	COG1739	Uncharacterized protein family UPF0029
GCK69_19900	COG0805	protein transport
GCK69_19910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK69_19930	COG1322	Protein conserved in bacteria
GCK69_19935	COG0586	Pfam SNARE associated Golgi protein
GCK69_19940	COG1966	Carbon starvation protein
GCK69_19950	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GCK69_19955	COG0412	Dienelactone hydrolase
GCK69_19965	COG0583	DNA-binding transcription factor activity
GCK69_19975	COG0679	Auxin Efflux Carrier
GCK69_19980	COG0584	glycerophosphoryl diester phosphodiesterase
GCK69_20040	COG0410	ABC transporter
GCK69_20045	COG0411	ABC transporter
GCK69_20050	COG4177	L-phenylalanine transmembrane transporter activity
GCK69_20060	COG0683	leucine binding
GCK69_20070	COG1943	Transposase
GCK69_20080	COG2177	Part of the ABC transporter FtsEX involved in
GCK69_20085	COG2884	Cell division ATP-binding protein ftsE
GCK69_20090	COG0552	protein localization to endoplasmic reticulum
GCK69_20090	COG0552	protein localization to endoplasmic reticulum
GCK69_20100	COG0742	ribosomal rna small subunit methyltransferase
GCK69_20105	COG3776	membrane
GCK69_20120	COG3714	YhhN family
GCK69_20135	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCK69_20145	COG0247	lactate metabolic process
GCK69_20155	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK69_20170	COG0584	glycerophosphoryl diester phosphodiesterase
GCK69_20180	COG0561	phosphatase activity
GCK69_20185	COG2267	carboxylic ester hydrolase activity
GCK69_20190	COG1280	lysine exporter protein (LysE YggA)
GCK69_20195	COG1280	lysine exporter protein (LysE YggA)
GCK69_20200	COG0514	ATP-dependent DNA helicase (RecQ)
GCK69_20205	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GCK69_20210	COG2050	protein possibly involved in aromatic compounds catabolism
GCK69_20220	COG0598	Magnesium transport protein CorA
GCK69_20225	COG5564	TIM-barrel signal transduction protein
GCK69_20230	COG5441	Belongs to the UPF0261 family
GCK69_20240	COG0210	DNA helicase
GCK69_20245	COG1011	Hydrolase
GCK69_20250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GCK69_20255	COG3159	Protein conserved in bacteria
GCK69_20265	COG5567	small periplasmic lipoprotein
GCK69_20275	COG3072	Adenylate cyclase
GCK69_20290	COG1587	Uroporphyrinogen-III synthase
GCK69_20295	COG2959	enzyme of heme biosynthesis
GCK69_20300	COG3071	HemY protein
GCK69_20335	COG1113	amino acid transport
GCK69_20355	COG2244	polysaccharide biosynthetic process
GCK69_20360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GCK69_20365	COG0456	acetyltransferase
GCK69_20370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GCK69_20375	COG1088	dTDP-glucose 4,6-dehydratase activity
GCK69_20380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCK69_20385	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCK69_20390	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK69_20395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCK69_20400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCK69_20405	COG3118	belongs to the thioredoxin family
GCK69_20430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK69_20440	COG3328	transposase activity
GCK69_20455	COG3121	Chaperone
GCK69_20470	COG3121	Chaperone
GCK69_20510	COG0583	DNA-binding transcription factor activity
GCK69_20555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK69_20560	COG3978	acetolactate synthase activity
GCK69_20585	COG3085	chromosome segregation
GCK69_20595	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_20600	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK69_20605	COG1129	ABC transporter
GCK69_20610	COG1879	ABC-type sugar transport system periplasmic component
GCK69_20690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK69_20690	COG0678	peroxiredoxin activity
GCK69_20695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK69_20720	COG1629	transport
GCK69_20735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCK69_20775	COG0527	aspartate kinase activity
GCK69_20775	COG0460	homoserine dehydrogenase
GCK69_20790	COG4682	membrane
GCK69_20800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCK69_20810	COG1609	Transcriptional regulator
GCK69_20815	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK69_20830	COG1575	Belongs to the MenA family. Type 1 subfamily
GCK69_20890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GCK69_20895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK69_20900	COG1494	fructose-1,6-bisphosphatase
GCK69_20910	COG3152	Membrane
GCK69_20925	COG0583	DNA-binding transcription factor activity
GCK69_20930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCK69_20935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCK69_20940	COG0471	metal ion transport
GCK69_20950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GCK69_20980	COG3678	ATP-independent chaperone mediated protein folding
GCK69_20985	COG0745	RESPONSE REGULATOR receiver
GCK69_20990	COG2205	protein histidine kinase activity
GCK69_20995	COG2169	Transcriptional regulator
GCK69_20995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK69_21000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCK69_21005	COG1045	serine acetyltransferase
GCK69_21025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK69_21030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCK69_21040	COG4942	peptidase
GCK69_21055	COG0156	8-amino-7-oxononanoate synthase activity
GCK69_21065	COG0859	PFAM glycosyl transferase family 9
GCK69_21070	COG0859	PFAM glycosyl transferase family 9
GCK69_21075	COG1519	Transferase
GCK69_21095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GCK69_21115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCK69_21140	COG1561	YicC-like family, N-terminal region
GCK69_21145	COG2860	membrane
GCK69_21150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GCK69_21165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK69_21170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK69_21175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK69_21185	COG0786	glutamate:sodium symporter activity
GCK69_21190	COG2233	PERMEase
GCK69_21195	COG2982	Protein involved in outer membrane biogenesis
GCK69_21200	COG0456	acetyltransferase
GCK69_21220	COG1295	ribonuclease BN
GCK69_21225	COG1011	Hydrolase
GCK69_21235	COG0174	glutamine synthetase
GCK69_21240	COG3852	Histidine kinase
GCK69_21250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK69_21275	COG1943	Transposase
GCK69_21280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK69_21280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK69_21285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK69_21290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCK69_21295	COG3084	Protein conserved in bacteria
GCK69_21305	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCK69_21310	COG3328	transposase activity
GCK69_21345	COG2186	Transcriptional regulator
GCK69_21350	COG0477	Major facilitator Superfamily
GCK69_21365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK69_21395	COG1522	sequence-specific DNA binding
GCK69_21400	COG0716	FMN binding
GCK69_21420	COG3312	ion transport
GCK69_21475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GCK69_21480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCK69_21485	COG0573	inorganic phosphate transmembrane transporter activity
GCK69_21490	COG0581	inorganic phosphate transmembrane transporter activity
GCK69_21500	COG0704	Plays a role in the regulation of phosphate uptake
GCK69_21510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK69_21515	COG0765	amino acid transport
GCK69_21520	COG0765	amino acid transport
GCK69_21525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK69_21535	COG2252	PERMEase
GCK69_21565	COG0706	membrane insertase activity
GCK69_21580	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GCK69_21645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GCK69_21655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK69_21780	COG1475	DNA binding
GCK69_21880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK69_21890	COG3344	reverse transcriptase
GCK69_21915	COG3328	transposase activity
GCK69_21955	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GCK69_21965	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK69_21965	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK69_22000	COG3941	tape measure
GCK69_22095	COG1475	DNA binding
GCK69_22100	COG1475	DNA binding
GCK69_22105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK69_22195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK69_22245	COG0515	serine threonine protein kinase
GCK69_22295	COG5599	Phosphatase
GCK69_22300	COG1317	bacterial-type flagellum organization
GCK69_22310	COG4669	(LipO)protein
GCK69_22360	COG2207	Transcriptional regulator
GCK69_22370	COG4792	protein secretion
GCK69_22375	COG4791	protein targeting
GCK69_22380	COG4794	Type iii secretion
GCK69_22385	COG4790	Type iii secretion
GCK69_22390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCK69_22435	COG4789	Type iii secretion
GCK69_22455	COG0457	Tetratricopeptide repeat
GCK69_22480	COG4886	Leucine-rich repeat (LRR) protein
GCK69_22490	COG3328	transposase activity
GCK69_22515	COG3177	Filamentation induced by cAMP protein fic
GCK69_22550	COG1192	Involved in chromosome partitioning
GCK69_22555	COG1475	DNA binding
GCK69_22570	COG3609	addiction module antidote protein, CC2985 family
GCK69_22580	COG5599	Phosphatase
GCK69_22715	COG4683	PFAM Phage derived protein Gp49-like (DUF891)