locus-tag	class	description
GCK70_00010	COG0592	DNA-directed DNA polymerase activity
GCK70_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GCK70_00020	COG0187	DNA topoisomerase II activity
GCK70_00025	COG0561	phosphatase activity
GCK70_00045	COG2423	ornithine cyclodeaminase activity
GCK70_00050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCK70_00065	COG5645	(Lipo)protein
GCK70_00085	COG3977	Valine--pyruvate aminotransferase
GCK70_00105	COG0366	Alpha amylase catalytic
GCK70_00125	COG2885	chlorophyll binding
GCK70_00135	COG2818	Glycosylase
GCK70_00160	COG2213	PTS system mannitol-specific
GCK70_00160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_00170	COG3722	fumarate hydratase activity
GCK70_00195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK70_00210	COG0437	4 iron, 4 sulfur cluster binding
GCK70_00215	COG2864	formate dehydrogenase
GCK70_00230	COG3276	selenocysteine insertion sequence binding
GCK70_00290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCK70_00305	COG1629	transport
GCK70_00330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK70_00335	COG0678	peroxiredoxin activity
GCK70_00335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK70_00415	COG1879	ABC-type sugar transport system periplasmic component
GCK70_00420	COG1129	ABC transporter
GCK70_00425	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_00430	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_00440	COG3085	chromosome segregation
GCK70_00465	COG3978	acetolactate synthase activity
GCK70_00470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK70_00515	COG0583	DNA-binding transcription factor activity
GCK70_00555	COG3121	Chaperone
GCK70_00570	COG3121	Chaperone
GCK70_00585	COG3328	transposase activity
GCK70_00595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK70_00620	COG3118	belongs to the thioredoxin family
GCK70_00625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCK70_00630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCK70_00635	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK70_00640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCK70_00645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCK70_00650	COG1088	dTDP-glucose 4,6-dehydratase activity
GCK70_00655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GCK70_00660	COG0456	acetyltransferase
GCK70_00665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GCK70_00670	COG2244	polysaccharide biosynthetic process
GCK70_00690	COG1113	amino acid transport
GCK70_00725	COG3071	HemY protein
GCK70_00730	COG2959	enzyme of heme biosynthesis
GCK70_00735	COG1587	Uroporphyrinogen-III synthase
GCK70_00750	COG3072	Adenylate cyclase
GCK70_00760	COG5567	small periplasmic lipoprotein
GCK70_00770	COG3159	Protein conserved in bacteria
GCK70_00775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GCK70_00780	COG1011	Hydrolase
GCK70_00785	COG0210	DNA helicase
GCK70_00795	COG5441	Belongs to the UPF0261 family
GCK70_00800	COG5564	TIM-barrel signal transduction protein
GCK70_00805	COG0598	Magnesium transport protein CorA
GCK70_00815	COG2050	protein possibly involved in aromatic compounds catabolism
GCK70_00820	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GCK70_00825	COG0514	ATP-dependent DNA helicase (RecQ)
GCK70_00830	COG1280	lysine exporter protein (LysE YggA)
GCK70_00835	COG1280	lysine exporter protein (LysE YggA)
GCK70_00840	COG2267	carboxylic ester hydrolase activity
GCK70_00845	COG0561	phosphatase activity
GCK70_00855	COG0584	glycerophosphoryl diester phosphodiesterase
GCK70_00870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK70_00880	COG0247	lactate metabolic process
GCK70_00890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCK70_00905	COG3714	YhhN family
GCK70_00920	COG3776	membrane
GCK70_00925	COG0742	ribosomal rna small subunit methyltransferase
GCK70_00935	COG0552	protein localization to endoplasmic reticulum
GCK70_00935	COG0552	protein localization to endoplasmic reticulum
GCK70_00940	COG2884	Cell division ATP-binding protein ftsE
GCK70_00945	COG2177	Part of the ABC transporter FtsEX involved in
GCK70_00955	COG1943	Transposase
GCK70_00965	COG0683	leucine binding
GCK70_00970	COG0559	Belongs to the binding-protein-dependent transport system permease family
GCK70_00975	COG4177	L-phenylalanine transmembrane transporter activity
GCK70_00980	COG0411	ABC transporter
GCK70_00985	COG0410	ABC transporter
GCK70_01000	COG3328	transposase activity
GCK70_01050	COG0584	glycerophosphoryl diester phosphodiesterase
GCK70_01055	COG0679	Auxin Efflux Carrier
GCK70_01065	COG0583	DNA-binding transcription factor activity
GCK70_01075	COG0412	Dienelactone hydrolase
GCK70_01080	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GCK70_01090	COG1966	Carbon starvation protein
GCK70_01095	COG0586	Pfam SNARE associated Golgi protein
GCK70_01100	COG1322	Protein conserved in bacteria
GCK70_01120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK70_01130	COG0805	protein transport
GCK70_01190	COG1739	Uncharacterized protein family UPF0029
GCK70_01205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GCK70_01210	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GCK70_01245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCK70_01300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK70_01305	COG0250	Participates in transcription elongation, termination and antitermination
GCK70_01340	COG1943	Transposase
GCK70_01365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCK70_01375	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GCK70_01400	COG1515	deoxyribonuclease V activity
GCK70_01405	COG3068	Protein conserved in bacteria
GCK70_01420	COG0151	Belongs to the GarS family
GCK70_01495	COG3162	membrane
GCK70_01505	COG1301	dicarboxylic acid transport
GCK70_01615	COG2391	methyltransferase activity
GCK70_01620	COG0425	Belongs to the sulfur carrier protein TusA family
GCK70_01625	COG0583	DNA-binding transcription factor activity
GCK70_01630	COG0814	amino acid
GCK70_01635	COG0626	cystathionine gamma-synthase activity
GCK70_01645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_01650	COG4558	Periplasmic binding protein
GCK70_01655	COG3720	iron ion transport
GCK70_01670	COG0702	epimerase
GCK70_01675	COG3721	Heme iron utilization protein
GCK70_01700	COG1358	cellular component organization or biogenesis
GCK70_01760	COG3121	Chaperone
GCK70_01815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCK70_01825	COG0735	belongs to the Fur family
GCK70_01830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK70_01845	COG0305	Participates in initiation and elongation during chromosome replication
GCK70_01850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK70_01855	COG1448	Aminotransferase
GCK70_01860	COG2315	Protein conserved in bacteria
GCK70_01865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCK70_01870	COG0629	single-stranded DNA binding
GCK70_01880	COG1454	alcohol dehydrogenase
GCK70_01950	COG1309	transcriptional regulator
GCK70_01960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_01960	COG0493	'glutamate synthase
GCK70_01965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_01970	COG3383	formate dehydrogenase (NAD+) activity
GCK70_01985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GCK70_02030	COG2076	Multidrug Resistance protein
GCK70_02035	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GCK70_02045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCK70_02050	COG1053	succinate dehydrogenase
GCK70_02065	COG1511	domain protein
GCK70_02065	COG3264	Mechanosensitive ion channel
GCK70_02085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GCK70_02105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCK70_02110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCK70_02110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCK70_02115	COG0802	atpase or kinase
GCK70_02120	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK70_02140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCK70_02145	COG0330	HflC and HflK could
GCK70_02150	COG0330	HflC and HflK could
GCK70_02155	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GCK70_02170	COG0557	exoribonuclease II activity
GCK70_02175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK70_02180	COG1960	acyl-CoA dehydrogenase activity
GCK70_02185	COG3650	response to hydrogen peroxide
GCK70_02205	COG1073	alpha beta
GCK70_02215	COG0360	Binds together with S18 to 16S ribosomal RNA
GCK70_02225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCK70_02245	COG3061	Opacity-associated protein A
GCK70_02250	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK70_02260	COG0737	Belongs to the 5'-nucleotidase family
GCK70_02270	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GCK70_02280	COG1253	flavin adenine dinucleotide binding
GCK70_02290	COG0729	surface antigen
GCK70_02295	COG2911	Protein conserved in bacteria
GCK70_02300	COG2105	PFAM AIG2 family protein
GCK70_02305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GCK70_02315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCK70_02340	COG3423	Transcriptional regulator
GCK70_02350	COG0142	geranyltranstransferase activity
GCK70_02365	COG0697	spore germination
GCK70_02375	COG0642	Histidine kinase
GCK70_02380	COG0745	RESPONSE REGULATOR receiver
GCK70_02385	COG2027	D-alanyl-D-alanine carboxypeptidase
GCK70_02390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK70_02395	COG1534	Rna-binding protein
GCK70_02405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GCK70_02410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GCK70_02420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK70_02440	COG0195	Participates in both transcription termination and antitermination
GCK70_02485	COG0513	Belongs to the DEAD box helicase family
GCK70_02510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCK70_02520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_02550	COG3153	acetyltransferase
GCK70_02570	COG1653	transport
GCK70_02580	COG0395	ABC-type sugar transport system, permease component
GCK70_02585	COG3842	ATPase activity
GCK70_02600	COG0702	epimerase
GCK70_02605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCK70_02610	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GCK70_02615	COG3454	Phosphonate metabolism
GCK70_02620	COG4778	phosphonate C-P lyase system protein PhnL
GCK70_02625	COG4107	phosphonate C-P lyase system protein PhnK
GCK70_02630	COG3627	carbon phosphorus lyase activity
GCK70_02635	COG3626	phosphonate metabolism
GCK70_02640	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GCK70_02645	COG3624	Phosphonate C-P lyase system protein PhnG
GCK70_02650	COG2188	Transcriptional regulator
GCK70_02665	COG4608	Belongs to the ABC transporter superfamily
GCK70_02670	COG0444	Belongs to the ABC transporter superfamily
GCK70_02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_02680	COG0601	transmembrane transport
GCK70_02690	COG2731	YhcH YjgK YiaL family protein
GCK70_02695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GCK70_02700	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GCK70_02710	COG0525	valine-tRNA ligase activity
GCK70_02715	COG2927	DNA polymerase III (CHI subunit)
GCK70_02725	COG0795	lipopolysaccharide-transporting ATPase activity
GCK70_02730	COG0795	lipopolysaccharide-transporting ATPase activity
GCK70_02740	COG0582	viral genome integration into host DNA
GCK70_02780	COG0237	dephospho-CoA kinase activity
GCK70_02795	COG1459	type II secretion system
GCK70_02800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCK70_02805	COG4969	Belongs to the N-Me-Phe pilin family
GCK70_02815	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK70_02820	COG3725	Membrane protein required for beta-lactamase induction
GCK70_02825	COG1113	amino acid transport
GCK70_02835	COG2186	Transcriptional regulator
GCK70_02840	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GCK70_02845	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK70_02850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK70_02855	COG1943	Transposase
GCK70_02860	COG1049	propionate catabolic process, 2-methylcitrate cycle
GCK70_02870	COG0697	spore germination
GCK70_02890	COG2132	Multicopper oxidase
GCK70_02895	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GCK70_02900	COG0288	reversible hydration of carbon dioxide
GCK70_02905	COG1131	(ABC) transporter
GCK70_02910	COG0842	Transport permease protein
GCK70_02935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GCK70_02940	COG0617	tRNA 3'-terminal CCA addition
GCK70_02945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCK70_02955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GCK70_02965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GCK70_02970	COG1643	Atp-dependent helicase
GCK70_02975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCK70_02980	COG1120	ATPase activity
GCK70_02985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK70_02990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_03010	COG2860	membrane
GCK70_03020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK70_03030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK70_03035	COG2205	protein histidine kinase activity
GCK70_03035	COG4999	Histidine kinase
GCK70_03035	COG3437	response regulator, receiver
GCK70_03035	COG3850	Histidine kinase
GCK70_03045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCK70_03050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK70_03055	COG3956	TIGRFAM MazG family protein
GCK70_03075	COG0602	queuosine metabolic process
GCK70_03080	COG0720	synthase
GCK70_03135	COG0529	Catalyzes the synthesis of activated sulfate
GCK70_03150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GCK70_03175	COG4942	peptidase
GCK70_03175	COG1388	LysM domain
GCK70_03180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCK70_03185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GCK70_03190	COG0698	ribose 5-phosphate isomerase
GCK70_03195	COG1063	alcohol dehydrogenase
GCK70_03200	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_03205	COG2376	Dihydroxyacetone kinase
GCK70_03220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCK70_03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_03245	COG1858	cytochrome C peroxidase
GCK70_03255	COG4771	TonB-dependent receptor
GCK70_03265	COG0024	Methionine aminopeptidase
GCK70_03275	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK70_03275	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK70_03280	COG1070	Carbohydrate kinase
GCK70_03285	COG3623	hexulose-6-phosphate isomerase
GCK70_03290	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_03295	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_03300	COG1129	ABC transporter
GCK70_03305	COG1943	Transposase
GCK70_03315	COG1349	DNA-binding transcription factor activity
GCK70_03320	COG0235	Class ii aldolase
GCK70_03325	COG0243	molybdopterin cofactor binding
GCK70_03330	COG0437	4 iron, 4 sulfur cluster binding
GCK70_03335	COG3302	dmso reductase anchor subunit
GCK70_03340	COG3381	protein complex oligomerization
GCK70_03345	COG3038	cytochrome b561
GCK70_03350	COG3783	Cytochrome b(562)
GCK70_03370	COG1129	ABC transporter
GCK70_03375	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_03380	COG3959	Transketolase, thiamine diphosphate binding domain
GCK70_03385	COG3958	Transketolase
GCK70_03390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK70_03430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GCK70_03435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GCK70_03465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_03470	COG1238	metal cluster binding
GCK70_03475	COG2918	glutathione biosynthetic process
GCK70_03490	COG4536	flavin adenine dinucleotide binding
GCK70_03495	COG4137	Cytochrome C assembly protein
GCK70_03500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCK70_03530	COG3137	Salt-induced outer membrane protein
GCK70_03540	COG3279	Response regulator of the LytR AlgR family
GCK70_03545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK70_03550	COG0287	Prephenate dehydrogenase
GCK70_03550	COG1605	Chorismate mutase
GCK70_03575	COG1943	Transposase
GCK70_03580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCK70_03585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK70_03595	COG0564	pseudouridine synthase activity
GCK70_03605	COG0542	response to heat
GCK70_03645	COG5544	Lipoprotein
GCK70_03650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK70_03655	COG1042	CoA-binding domain protein
GCK70_03655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK70_03655	COG0045	succinate-CoA ligase (ADP-forming) activity
GCK70_03665	COG3118	belongs to the thioredoxin family
GCK70_03670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK70_03675	COG2814	Major facilitator Superfamily
GCK70_03680	COG1566	PFAM secretion protein HlyD family protein
GCK70_03685	COG1846	Transcriptional regulator
GCK70_03695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GCK70_03700	COG2814	Major facilitator Superfamily
GCK70_03750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK70_03765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK70_03790	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
GCK70_03800	COG1960	acyl-CoA dehydrogenase activity
GCK70_03810	COG0121	glutamine amidotransferase
GCK70_03815	COG3034	peptidoglycan biosynthetic process
GCK70_03825	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK70_03830	COG1805	sodium ion transport
GCK70_03835	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK70_03855	COG1477	protein flavinylation
GCK70_03875	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK70_03880	COG0583	DNA-binding transcription factor activity
GCK70_03930	COG2226	methyltransferase
GCK70_03960	COG1940	carbohydrate kinase activity
GCK70_03965	COG0419	ATPase involved in DNA repair
GCK70_03970	COG0420	3'-5' exonuclease activity
GCK70_03975	COG0745	RESPONSE REGULATOR receiver
GCK70_03980	COG5002	protein histidine kinase activity
GCK70_03990	COG1114	Component of the transport system for branched-chain amino acids
GCK70_04000	COG0366	Alpha amylase catalytic
GCK70_04025	COG1943	Transposase
GCK70_04030	COG0450	alkyl hydroperoxide reductase
GCK70_04035	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GCK70_04040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GCK70_04050	COG1862	Preprotein translocase
GCK70_04055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK70_04060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK70_04070	COG1943	Transposase
GCK70_04095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK70_04095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK70_04110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GCK70_04115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCK70_04130	COG0142	geranyltranstransferase activity
GCK70_04145	COG0693	protein deglycase activity
GCK70_04150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCK70_04165	COG2814	Major facilitator Superfamily
GCK70_04175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCK70_04180	COG1845	cytochrome c oxidase, subunit III
GCK70_04185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCK70_04190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCK70_04200	COG2223	nitrite transmembrane transporter activity
GCK70_04205	COG3056	Lipoprotein
GCK70_04210	COG0271	Belongs to the BolA IbaG family
GCK70_04235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GCK70_04240	COG0776	regulation of translation
GCK70_04245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK70_04250	COG1555	photosystem II stabilization
GCK70_04255	COG0824	Thioesterase
GCK70_04265	COG4533	DNA binding
GCK70_04280	COG1522	sequence-specific DNA binding
GCK70_04285	COG1132	(ABC) transporter
GCK70_04290	COG1132	(ABC) transporter
GCK70_04295	COG0347	Belongs to the P(II) protein family
GCK70_04300	COG0004	ammonium transporteR
GCK70_04305	COG1946	Acyl-CoA thioesterase
GCK70_04310	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GCK70_04315	COG3695	enzyme binding
GCK70_04340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK70_04350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_04355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_04360	COG1309	transcriptional regulator
GCK70_04365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GCK70_04370	COG3264	Mechanosensitive ion channel
GCK70_04370	COG1196	nuclear chromosome segregation
GCK70_04385	COG2832	Protein of unknown function (DUF454)
GCK70_04395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCK70_04425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_04425	COG0543	2 iron, 2 sulfur cluster binding
GCK70_04450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_04495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_04515	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK70_04520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_04525	COG4651	solute:proton antiporter activity
GCK70_04525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK70_04530	COG2223	nitrite transmembrane transporter activity
GCK70_04545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCK70_04550	COG3735	TraB family
GCK70_04555	COG2217	Heavy metal translocating P-type atpase
GCK70_04560	COG0789	Transcriptional regulator
GCK70_04565	COG1585	Membrane protein implicated in regulation of membrane protease activity
GCK70_04570	COG0330	HflC and HflK could
GCK70_04575	COG3118	belongs to the thioredoxin family
GCK70_04580	COG0300	oxidoreductase activity
GCK70_04585	COG2755	lipolytic protein G-D-S-L family
GCK70_04590	COG4181	ATPase activity
GCK70_04595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GCK70_04600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GCK70_04605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCK70_04620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK70_04630	COG1943	Transposase
GCK70_04635	COG2501	S4 domain
GCK70_04670	COG0582	viral genome integration into host DNA
GCK70_04685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCK70_04690	COG4589	Belongs to the CDS family
GCK70_04700	COG2267	carboxylic ester hydrolase activity
GCK70_04705	COG2453	phosphatase
GCK70_04705	COG0671	phosphoesterase, PA-phosphatase related
GCK70_04740	COG0667	Aldo Keto reductase
GCK70_04745	COG0656	L-ascorbic acid biosynthetic process
GCK70_04770	COG3328	transposase activity
GCK70_04825	COG3423	Transcriptional regulator
GCK70_04830	COG4953	penicillin-binding protein 1C
GCK70_04835	COG1943	Transposase
GCK70_04840	COG2373	Large extracellular alpha-helical protein
GCK70_04860	COG3962	Belongs to the TPP enzyme family
GCK70_04870	COG1879	ABC-type sugar transport system periplasmic component
GCK70_04875	COG1129	ABC transporter
GCK70_04880	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_04885	COG0673	inositol 2-dehydrogenase activity
GCK70_04890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_04900	COG3718	enzyme involved in inositol metabolism
GCK70_04910	COG5265	(ABC) transporter
GCK70_04935	COG2197	response regulator
GCK70_04940	COG1278	Cold shock
GCK70_04945	COG1278	Cold shock
GCK70_04950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK70_04955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK70_04980	COG1686	Belongs to the peptidase S11 family
GCK70_04985	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK70_04990	COG0772	Belongs to the SEDS family
GCK70_04995	COG0768	penicillin binding
GCK70_05005	COG0799	negative regulation of ribosome biogenesis
GCK70_05015	COG1466	dna polymerase III delta subunit
GCK70_05030	COG2888	peptidyl-tyrosine sulfation
GCK70_05035	COG1126	abc transporter atp-binding protein
GCK70_05040	COG0765	amino acid transport
GCK70_05045	COG0765	amino acid transport
GCK70_05055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GCK70_05060	COG4535	Mg2 and Co2 transporter CorC
GCK70_05070	COG1702	phosphate starvation-inducible protein PhoH
GCK70_05080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK70_05120	COG0367	asparagine synthase
GCK70_05125	COG0647	UMP catabolic process
GCK70_05130	COG1846	Transcriptional regulator
GCK70_05130	COG1940	carbohydrate kinase activity
GCK70_05135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GCK70_05145	COG2190	(PTS) system
GCK70_05145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_05145	COG1263	PTS System
GCK70_05150	COG1943	Transposase
GCK70_05175	COG0735	belongs to the Fur family
GCK70_05195	COG0596	Alpha beta hydrolase
GCK70_05205	COG0582	viral genome integration into host DNA
GCK70_05235	COG2113	Glycine betaine
GCK70_05240	COG4176	ABC-type proline glycine betaine transport system permease component
GCK70_05245	COG4175	Glycine betaine
GCK70_05250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCK70_05290	COG1278	Cold shock
GCK70_05295	COG0747	negative chemotaxis
GCK70_05305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_05310	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GCK70_05315	COG1124	(ABC) transporter
GCK70_05345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GCK70_05355	COG4413	Urea transporter
GCK70_05360	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK70_05370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK70_05375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK70_05380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK70_05390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK70_05395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK70_05400	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCK70_05405	COG2169	Transcriptional regulator
GCK70_05405	COG1917	Cupin 2, conserved barrel domain protein
GCK70_05425	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GCK70_05430	COG0033	Phosphoglucomutase
GCK70_05445	COG0745	RESPONSE REGULATOR receiver
GCK70_05450	COG2205	protein histidine kinase activity
GCK70_05490	COG3272	Protein of unknown function (DUF1722)
GCK70_05500	COG5212	phosphodiesterase
GCK70_05505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCK70_05515	COG1984	allophanate hydrolase subunit 2
GCK70_05565	COG0513	Belongs to the DEAD box helicase family
GCK70_05575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCK70_05585	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GCK70_05590	COG3026	antisigma factor binding
GCK70_05595	COG3086	response to oxidative stress
GCK70_05610	COG0681	Belongs to the peptidase S26 family
GCK70_05630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GCK70_05640	COG1943	Transposase
GCK70_05645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_05650	COG1737	Transcriptional regulator
GCK70_05660	COG0560	Phosphoserine phosphatase
GCK70_05665	COG0590	tRNA wobble adenosine to inosine editing
GCK70_05710	COG2205	protein histidine kinase activity
GCK70_05715	COG3170	Tfp pilus assembly protein FimV
GCK70_05720	COG2204	response regulator
GCK70_05725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCK70_05725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK70_05730	COG0347	Belongs to the P(II) protein family
GCK70_05740	COG1017	nitric oxide dioxygenase activity
GCK70_05740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_05760	COG2814	Major facilitator Superfamily
GCK70_05765	COG3711	transcriptional antiterminator
GCK70_05770	COG3683	transport system, periplasmic component
GCK70_05775	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK70_05780	COG0483	inositol monophosphate 1-phosphatase activity
GCK70_05795	COG1104	cysteine desulfurase activity
GCK70_05800	COG0822	iron-sulfur transferase activity
GCK70_05820	COG0443	Heat shock 70 kDa protein
GCK70_05825	COG0633	Ferredoxin
GCK70_05830	COG2975	iron-sulfur cluster assembly
GCK70_05855	COG3468	outer membrane autotransporter barrel domain protein
GCK70_05860	COG3468	outer membrane autotransporter barrel domain protein
GCK70_05905	COG2976	Protein conserved in bacteria
GCK70_05910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK70_05925	COG1645	bacterial-type flagellum-dependent swarming motility
GCK70_05935	COG0516	GMP reductase activity
GCK70_05935	COG0517	IMP dehydrogenase activity
GCK70_05945	COG1943	Transposase
GCK70_05985	COG3328	transposase activity
GCK70_06000	COG0351	phosphomethylpyrimidine kinase
GCK70_06030	COG3422	double-strand break repair
GCK70_06035	COG0745	RESPONSE REGULATOR receiver
GCK70_06065	COG3842	ATPase activity
GCK70_06075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCK70_06085	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK70_06090	COG1177	transmembrane transport
GCK70_06095	COG0443	Heat shock 70 kDa protein
GCK70_06100	COG2239	Acts as a magnesium transporter
GCK70_06110	COG0248	Ppx GppA phosphatase
GCK70_06115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCK70_06125	COG0581	inorganic phosphate transmembrane transporter activity
GCK70_06140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK70_06145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCK70_06160	COG1943	Transposase
GCK70_06170	COG1393	Belongs to the ArsC family
GCK70_06175	COG4783	chaperone-mediated protein folding
GCK70_06180	COG0628	permease
GCK70_06195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCK70_06200	COG2716	regulation of RNA biosynthetic process
GCK70_06210	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GCK70_06215	COG1943	Transposase
GCK70_06230	COG2321	neutral zinc metallopeptidase
GCK70_06255	COG1876	peptidase activity
GCK70_06265	COG1393	Belongs to the ArsC family
GCK70_06275	COG1840	ABC-type Fe3 transport system, periplasmic component
GCK70_06280	COG1175	transmembrane transport
GCK70_06295	COG3119	arylsulfatase activity
GCK70_06300	COG0641	radical SAM
GCK70_06305	COG1988	membrane-bound metal-dependent
GCK70_06315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_06325	COG2197	response regulator
GCK70_06330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_06330	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_06335	COG3062	negative regulation of establishment of protein localization
GCK70_06345	COG3043	anaerobic respiration
GCK70_06350	COG3005	denitrification pathway
GCK70_06395	COG3111	PFAM Bacterial OB fold (BOF) protein
GCK70_06405	COG2837	iron assimilation
GCK70_06410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCK70_06420	COG4886	Leucine-rich repeat (LRR) protein
GCK70_06430	COG2731	YhcH YjgK YiaL family protein
GCK70_06440	COG1737	Transcriptional regulator
GCK70_06450	COG4150	thiosulfate binding
GCK70_06455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GCK70_06460	COG4208	sulfate ABC transporter
GCK70_06465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCK70_06480	COG0745	RESPONSE REGULATOR receiver
GCK70_06485	COG3850	Histidine kinase
GCK70_06485	COG5002	protein histidine kinase activity
GCK70_06495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GCK70_06505	COG0006	proline dipeptidase activity
GCK70_06515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GCK70_06530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_06535	COG0745	RESPONSE REGULATOR receiver
GCK70_06540	COG2205	protein histidine kinase activity
GCK70_06550	COG2190	(PTS) system
GCK70_06560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_06565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GCK70_06570	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GCK70_06585	COG3530	Putative quorum-sensing-regulated virulence factor
GCK70_06610	COG1943	Transposase
GCK70_06650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK70_06665	COG0667	Aldo Keto reductase
GCK70_06690	COG0436	Aminotransferase
GCK70_06700	COG3038	cytochrome b561
GCK70_06730	COG3381	protein complex oligomerization
GCK70_06735	COG3302	dmso reductase anchor subunit
GCK70_06740	COG0437	4 iron, 4 sulfur cluster binding
GCK70_06745	COG0243	molybdopterin cofactor binding
GCK70_06780	COG2951	lytic endotransglycosylase activity
GCK70_06840	COG3121	Chaperone
GCK70_06845	COG3188	usher protein
GCK70_06855	COG3328	transposase activity
GCK70_06860	COG3188	usher protein
GCK70_06920	COG3501	Rhs element vgr protein
GCK70_06950	COG2824	Alkylphosphonate utilization operon protein PhnA
GCK70_06960	COG1704	LemA family
GCK70_06980	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK70_06985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK70_06990	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK70_07000	COG1138	Cytochrome C-type biogenesis protein
GCK70_07005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCK70_07010	COG3088	subunit of a heme lyase
GCK70_07010	COG4235	cytochrome complex assembly
GCK70_07015	COG3088	subunit of a heme lyase
GCK70_07015	COG4235	cytochrome complex assembly
GCK70_07030	COG3691	Protein conserved in bacteria
GCK70_07045	COG2062	phosphohistidine phosphatase, SixA
GCK70_07055	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK70_07070	COG0730	response to heat
GCK70_07075	COG3101	peptidyl-lysine hydroxylation
GCK70_07090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK70_07095	COG1794	racemase activity, acting on amino acids and derivatives
GCK70_07110	COG0697	spore germination
GCK70_07125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK70_07135	COG0586	Pfam SNARE associated Golgi protein
GCK70_07145	COG0285	dihydrofolate synthase activity
GCK70_07150	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GCK70_07155	COG1286	toxin biosynthetic process
GCK70_07160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GCK70_07165	COG0163	prenyltransferase activity
GCK70_07170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_07175	COG4215	(ABC) transporter
GCK70_07180	COG4160	amino acid transport
GCK70_07185	COG4598	ABC transporter
GCK70_07190	COG1090	epimerase
GCK70_07205	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GCK70_07210	COG3037	sugar-specific permease SgaT UlaA
GCK70_07215	COG3328	transposase activity
GCK70_07235	COG1609	Transcriptional regulator
GCK70_07240	COG0857	belongs to the CobB CobQ family
GCK70_07240	COG0280	phosphate acetyltransferase
GCK70_07260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_07265	COG0471	metal ion transport
GCK70_07265	COG0490	domain, Protein
GCK70_07280	COG0436	Aminotransferase
GCK70_07285	COG0583	DNA-binding transcription factor activity
GCK70_07295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK70_07305	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GCK70_07315	COG1034	ATP synthesis coupled electron transport
GCK70_07330	COG0839	Belongs to the complex I subunit 6 family
GCK70_07340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCK70_07345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK70_07360	COG2731	YhcH YjgK YiaL family protein
GCK70_07365	COG3265	gluconokinase activity
GCK70_07370	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_07380	COG1609	Transcriptional regulator
GCK70_07385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK70_07400	COG0129	dihydroxy-acid dehydratase activity
GCK70_07415	COG4575	ribosome binding
GCK70_07425	COG1169	isochorismate synthase
GCK70_07440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GCK70_07455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCK70_07500	COG1126	abc transporter atp-binding protein
GCK70_07505	COG0765	amino acid transport
GCK70_07510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_07540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK70_07560	COG1063	alcohol dehydrogenase
GCK70_07565	COG1879	ABC-type sugar transport system periplasmic component
GCK70_07570	COG1129	ABC transporter
GCK70_07575	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_07580	COG1609	Transcriptional regulator
GCK70_07585	COG0583	DNA-binding transcription factor activity
GCK70_07590	COG0473	3-isopropylmalate dehydrogenase activity
GCK70_07600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK70_07605	COG4638	Rieske (2fe-2S)
GCK70_07610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_07615	COG2831	hemolysin activation secretion protein
GCK70_07620	COG3210	domain, Protein
GCK70_07640	COG3210	domain, Protein
GCK70_07660	COG3210	domain, Protein
GCK70_07665	COG3210	domain, Protein
GCK70_07675	COG3842	ATPase activity
GCK70_07685	COG1609	Transcriptional regulator
GCK70_07700	COG0395	ABC-type sugar transport system, permease component
GCK70_07705	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCK70_07725	COG0668	transmembrane transport
GCK70_07730	COG1518	maintenance of DNA repeat elements
GCK70_07735	COG1203	CRISPR-associated helicase, Cas3
GCK70_07760	COG0667	Aldo Keto reductase
GCK70_07770	COG0477	Major facilitator Superfamily
GCK70_07780	COG0583	DNA-binding transcription factor activity
GCK70_07785	COG2771	luxR family
GCK70_07790	COG3916	Acyl-homoserine-lactone synthase
GCK70_07810	COG0628	permease
GCK70_07830	COG3328	transposase activity
GCK70_07855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GCK70_07870	COG3328	transposase activity
GCK70_07875	COG1530	ribonuclease E activity
GCK70_07880	COG0564	pseudouridine synthase activity
GCK70_07890	COG1399	metal-binding, possibly nucleic acid-binding protein
GCK70_07895	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GCK70_07915	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_07925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK70_07935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK70_07940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCK70_07950	COG0470	DNA polymerase III
GCK70_07955	COG0084	hydrolase, TatD family'
GCK70_07960	COG1263	PTS System
GCK70_07960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_07970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCK70_07975	COG0537	adenosine 5'-monophosphoramidase activity
GCK70_07980	COG5633	Lipoprotein
GCK70_07995	COG1472	Belongs to the glycosyl hydrolase 3 family
GCK70_08005	COG1252	NADH dehydrogenase
GCK70_08025	COG3328	transposase activity
GCK70_08035	COG3134	Outer membrane lipoprotein
GCK70_08040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCK70_08045	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK70_08055	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK70_08070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GCK70_08085	COG2850	peptidyl-arginine hydroxylation
GCK70_08095	COG0745	RESPONSE REGULATOR receiver
GCK70_08105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GCK70_08125	COG1187	pseudouridine synthase activity
GCK70_08130	COG0538	isocitrate dehydrogenase activity
GCK70_08145	COG0840	transmembrane signaling receptor activity
GCK70_08150	COG0702	epimerase
GCK70_08155	COG1733	regulation of RNA biosynthetic process
GCK70_08175	COG1522	sequence-specific DNA binding
GCK70_08185	COG0604	alcohol dehydrogenase
GCK70_08185	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_08185	COG3321	synthase
GCK70_08195	COG1278	Cold shock
GCK70_08210	COG1285	pathogenesis
GCK70_08235	COG1360	Flagellar Motor Protein
GCK70_08240	COG0643	Histidine kinase
GCK70_08240	COG2198	Histidine kinase
GCK70_08245	COG0835	chemotaxis
GCK70_08250	COG2271	Major facilitator Superfamily
GCK70_08255	COG0251	oxidation-reduction process
GCK70_08265	COG2964	Protein conserved in bacteria
GCK70_08285	COG0840	transmembrane signaling receptor activity
GCK70_08290	COG0840	transmembrane signaling receptor activity
GCK70_08295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCK70_08305	COG0745	RESPONSE REGULATOR receiver
GCK70_08310	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GCK70_08320	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK70_08330	COG5295	Hep Hag repeat protein
GCK70_08340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK70_08395	COG3121	Chaperone
GCK70_08415	COG3008	intermembrane lipid transfer
GCK70_08420	COG2995	paraquat-inducible protein a
GCK70_08425	COG1956	GAF domain-containing protein
GCK70_08435	COG0793	Belongs to the peptidase S41A family
GCK70_08450	COG3539	Fimbrial protein
GCK70_08455	COG3121	Chaperone
GCK70_08470	COG3121	Chaperone
GCK70_08475	COG2814	Major facilitator Superfamily
GCK70_08480	COG0823	Involved in the tonB-independent uptake of proteins
GCK70_08490	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK70_08500	COG1988	membrane-bound metal-dependent
GCK70_08505	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK70_08510	COG1653	transport
GCK70_08515	COG3842	ATPase activity
GCK70_08520	COG0395	ABC-type sugar transport system, permease component
GCK70_08525	COG1175	transmembrane transport
GCK70_08535	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_08545	COG1917	Cupin 2, conserved barrel domain protein
GCK70_08550	COG3328	transposase activity
GCK70_08555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_08575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK70_08580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK70_08585	COG1121	(ABC) transporter
GCK70_08590	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCK70_08615	COG4249	Peptidase C14 caspase catalytic subunit p20
GCK70_08645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GCK70_08650	COG0072	phenylalanine-tRNA ligase activity
GCK70_08650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCK70_08655	COG0776	regulation of translation
GCK70_08670	COG0386	Belongs to the glutathione peroxidase family
GCK70_08675	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GCK70_08720	COG0791	NLP P60 protein
GCK70_08745	COG0574	Belongs to the PEP-utilizing enzyme family
GCK70_08745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK70_08755	COG0628	permease
GCK70_08760	COG0277	FAD linked oxidase domain protein
GCK70_08760	COG0247	lactate metabolic process
GCK70_08765	COG2050	protein possibly involved in aromatic compounds catabolism
GCK70_08775	COG0316	Belongs to the HesB IscA family
GCK70_08780	COG0719	Fe-S assembly protein
GCK70_08785	COG0396	ATPase activity
GCK70_08790	COG0719	Fe-S assembly protein
GCK70_08805	COG1388	LysM domain
GCK70_08805	COG1376	ErfK ybiS ycfS ynhG family protein
GCK70_08825	COG4238	major outer membrane lipoprotein
GCK70_08855	COG0307	riboflavin synthase, alpha
GCK70_08860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCK70_08865	COG2814	Major facilitator Superfamily
GCK70_08870	COG0583	DNA-binding transcription factor activity
GCK70_08885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK70_08890	COG0791	NLP P60 protein
GCK70_08900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GCK70_08910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK70_08915	COG0346	lactoylglutathione lyase activity
GCK70_08925	COG1902	pentaerythritol trinitrate reductase activity
GCK70_08930	COG1309	transcriptional regulator
GCK70_08935	COG2194	sulfuric ester hydrolase activity
GCK70_08940	COG3313	Fe-S protein
GCK70_08945	COG4989	oxidoreductase activity
GCK70_08960	COG3133	Outer membrane lipoprotein
GCK70_08970	COG3895	Periplasmic Protein
GCK70_08990	COG0625	glutathione transferase activity
GCK70_09005	COG3104	oligopeptide transport
GCK70_09010	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK70_09010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK70_09015	COG4172	Belongs to the ABC transporter superfamily
GCK70_09025	COG4171	peptide transport system, permease
GCK70_09030	COG4168	peptide transport system, permease
GCK70_09035	COG4166	transmembrane transport
GCK70_09050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GCK70_09055	COG1842	Phage shock protein A
GCK70_09065	COG1983	PspC domain protein
GCK70_09075	COG3106	COG3106 Predicted ATPase
GCK70_09100	COG1943	Transposase
GCK70_09105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GCK70_09110	COG4948	Mandelate Racemase Muconate Lactonizing
GCK70_09115	COG2866	Carboxypeptidase
GCK70_09120	COG4166	transmembrane transport
GCK70_09140	COG0657	acetylesterase activity
GCK70_09140	COG2755	lipolytic protein G-D-S-L family
GCK70_09150	COG0674	pyruvate-flavodoxin oxidoreductase activity
GCK70_09150	COG1013	pyruvate-flavodoxin oxidoreductase activity
GCK70_09150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GCK70_09150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK70_09160	COG1285	pathogenesis
GCK70_09165	COG3042	response to heat
GCK70_09170	COG3187	Heat shock protein
GCK70_09175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK70_09180	COG2911	Protein conserved in bacteria
GCK70_09190	COG3784	Protein of unknown function (DUF1318)
GCK70_09195	COG0246	Mannitol dehydrogenase
GCK70_09200	COG2390	Transcriptional regulator
GCK70_09210	COG1643	Atp-dependent helicase
GCK70_09225	COG3591	Belongs to the peptidase S1B family
GCK70_09240	COG3038	cytochrome b561
GCK70_09265	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GCK70_09270	COG2205	protein histidine kinase activity
GCK70_09275	COG0745	RESPONSE REGULATOR receiver
GCK70_09285	COG0531	amino acid
GCK70_09300	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GCK70_09305	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GCK70_09310	COG0589	response to stress
GCK70_09315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCK70_09320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK70_09335	COG1011	Hydrolase
GCK70_09340	COG0440	acetolactate synthase activity
GCK70_09345	COG0028	Belongs to the TPP enzyme family
GCK70_09375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK70_09385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK70_09390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK70_09405	COG1609	Transcriptional regulator
GCK70_09415	COG0038	chloride channel
GCK70_09420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK70_09425	COG1940	carbohydrate kinase activity
GCK70_09430	COG0583	DNA-binding transcription factor activity
GCK70_09435	COG2814	Major facilitator Superfamily
GCK70_09445	COG0114	fumarate hydratase activity
GCK70_09455	COG5339	Protein conserved in bacteria
GCK70_09465	COG0385	Bile acid
GCK70_09470	COG0673	inositol 2-dehydrogenase activity
GCK70_09480	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_09490	COG1879	ABC-type sugar transport system periplasmic component
GCK70_09505	COG2274	protein secretion by the type I secretion system
GCK70_09510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_09545	COG3708	Transcriptional regulator
GCK70_09545	COG2207	Transcriptional regulator
GCK70_09550	COG4658	electron transport chain
GCK70_09555	COG4659	FMN binding
GCK70_09565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCK70_09570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_09575	COG2271	Major facilitator Superfamily
GCK70_09585	COG1966	Carbon starvation protein
GCK70_09590	COG2879	small protein
GCK70_09595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCK70_09615	COG0023	Translation Initiation Factor
GCK70_09630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GCK70_09635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GCK70_09640	COG0671	phosphoesterase, PA-phosphatase related
GCK70_09645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GCK70_09650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCK70_09660	COG0583	DNA-binding transcription factor activity
GCK70_09665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK70_09680	COG0616	signal peptide processing
GCK70_09685	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_09695	COG1187	pseudouridine synthase activity
GCK70_09700	COG0009	L-threonylcarbamoyladenylate synthase
GCK70_09725	COG0512	Glutamine amidotransferase of anthranilate synthase
GCK70_09735	COG0134	indole-3-glycerol-phosphate synthase activity
GCK70_09735	COG0135	phosphoribosylanthranilate isomerase activity
GCK70_09755	COG3047	cAMP biosynthetic process
GCK70_09790	COG1607	acyl-coa hydrolase
GCK70_09795	COG3328	transposase activity
GCK70_09800	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GCK70_09805	COG2350	Protein conserved in bacteria
GCK70_09845	COG4608	Belongs to the ABC transporter superfamily
GCK70_09850	COG0444	Belongs to the ABC transporter superfamily
GCK70_09855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_09860	COG0601	transmembrane transport
GCK70_09870	COG2095	MarC family integral membrane protein
GCK70_09880	COG1454	alcohol dehydrogenase
GCK70_09880	COG1012	belongs to the aldehyde dehydrogenase family
GCK70_09900	COG1435	thymidine kinase activity
GCK70_09915	COG0745	RESPONSE REGULATOR receiver
GCK70_09925	COG0788	formyltetrahydrofolate deformylase activity
GCK70_09930	COG3328	transposase activity
GCK70_09950	COG3328	transposase activity
GCK70_09955	COG0583	DNA-binding transcription factor activity
GCK70_09960	COG0708	Exodeoxyribonuclease III
GCK70_09965	COG0494	nUDIX hydrolase
GCK70_09975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK70_09980	COG0709	Synthesizes selenophosphate from selenide and ATP
GCK70_09985	COG0778	Nitroreductase
GCK70_09990	COG0616	signal peptide processing
GCK70_09995	COG0252	asparaginase activity
GCK70_10000	COG1335	isochorismatase
GCK70_10005	COG3139	Protein of unknown function (DUF1315)
GCK70_10025	COG3713	MltA-interacting MipA family protein
GCK70_10035	COG2766	serine protein kinase
GCK70_10050	COG0583	DNA-binding transcription factor activity
GCK70_10060	COG2814	Major facilitator Superfamily
GCK70_10070	COG2719	SpoVR family
GCK70_10105	COG1104	cysteine desulfurase activity
GCK70_10115	COG3328	transposase activity
GCK70_10285	COG3328	transposase activity
GCK70_10380	COG0582	viral genome integration into host DNA
GCK70_10390	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCK70_10395	COG2951	lytic endotransglycosylase activity
GCK70_10410	COG2894	cell division
GCK70_10415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GCK70_10420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GCK70_10425	COG0318	PFAM AMP-dependent synthetase and ligase
GCK70_10435	COG3065	identical protein binding
GCK70_10445	COG1199	ATP-dependent helicase activity
GCK70_10450	COG0251	oxidation-reduction process
GCK70_10465	COG0800	Aldolase
GCK70_10475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCK70_10480	COG1737	Transcriptional regulator
GCK70_10485	COG0469	pyruvate kinase activity
GCK70_10495	COG1560	Kdo2-lipid A biosynthetic process
GCK70_10500	COG0739	heme binding
GCK70_10505	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GCK70_10515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK70_10545	COG0494	nUDIX hydrolase
GCK70_10555	COG1801	Protein of unknown function DUF72
GCK70_10560	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GCK70_10580	COG3102	Protein conserved in bacteria
GCK70_10600	COG0728	peptidoglycan biosynthetic process
GCK70_10610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK70_10625	COG3381	protein complex oligomerization
GCK70_10640	COG1940	carbohydrate kinase activity
GCK70_10645	COG0584	glycerophosphoryl diester phosphodiesterase
GCK70_10675	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK70_10680	COG3833	ABC-type maltose transport systems, permease component
GCK70_10705	COG0659	secondary active sulfate transmembrane transporter activity
GCK70_10715	COG2912	Transglutaminase-like superfamily
GCK70_10720	COG3094	Invasion gene expression up-regulator, SirB
GCK70_10725	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK70_10750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GCK70_10765	COG0012	GTP binding
GCK70_10820	COG5002	protein histidine kinase activity
GCK70_10860	COG0500	methyltransferase
GCK70_10885	COG3328	transposase activity
GCK70_10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_10950	COG0402	S-adenosylhomocysteine deaminase activity
GCK70_11010	COG0395	ABC-type sugar transport system, permease component
GCK70_11015	COG1175	transmembrane transport
GCK70_11025	COG0673	inositol 2-dehydrogenase activity
GCK70_11180	COG2197	response regulator
GCK70_11190	COG3136	membrane protein required for alginate biosynthesis
GCK70_11215	COG1113	amino acid transport
GCK70_11230	COG2837	iron assimilation
GCK70_11255	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK70_11255	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK70_11255	COG0506	proline dehydrogenase activity
GCK70_11285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GCK70_11295	COG1191	sigma factor activity
GCK70_11330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GCK70_11335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCK70_11340	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GCK70_11360	COG1677	Flagellar hook-basal body complex protein FliE
GCK70_11370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCK70_11380	COG1157	protein secretion by the type III secretion system
GCK70_11385	COG2882	bacterial-type flagellum organization
GCK70_11395	COG1580	Controls the rotational direction of flagella during chemotaxis
GCK70_11420	COG1987	bacterial-type flagellum assembly
GCK70_11440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_11445	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_11450	COG1129	ABC transporter
GCK70_11460	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_11465	COG3347	Dehydrogenase
GCK70_11465	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_11470	COG2390	Transcriptional regulator
GCK70_11480	COG1256	bacterial-type flagellum assembly
GCK70_11500	COG4786	Flagellar basal body rod
GCK70_11510	COG1749	Flagellar hook protein flgE
GCK70_11515	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK70_11520	COG1558	bacterial-type flagellum-dependent cell motility
GCK70_11525	COG1815	bacterial-type flagellum-dependent cell motility
GCK70_11535	COG2747	anti-sigma28 factor FlgM
GCK70_11540	COG3418	PFAM FlgN family protein
GCK70_11565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK70_11570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK70_11600	COG2372	response to copper ion
GCK70_11605	COG1528	Iron-storage protein
GCK70_11620	COG1770	oligopeptidase
GCK70_11635	COG3141	response to X-ray
GCK70_11640	COG0513	Belongs to the DEAD box helicase family
GCK70_11665	COG1760	l-serine dehydratase
GCK70_11670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCK70_11675	COG2368	4-hydroxyphenylacetate
GCK70_11690	COG3971	2-oxopent-4-enoate hydratase activity
GCK70_11700	COG3384	dioxygenase
GCK70_11705	COG1012	belongs to the aldehyde dehydrogenase family
GCK70_11720	COG1846	Transcriptional regulator
GCK70_11730	COG1253	flavin adenine dinucleotide binding
GCK70_11735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_11735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_11740	COG3715	PTS system
GCK70_11745	COG3716	PTS system mannose fructose sorbose family IID component
GCK70_11765	COG5001	Diguanylate cyclase
GCK70_11765	COG5002	protein histidine kinase activity
GCK70_11765	COG3447	MASE1 domain protein
GCK70_11775	COG2226	methyltransferase
GCK70_11785	COG1278	Cold shock
GCK70_11805	COG1113	amino acid transport
GCK70_11845	COG2207	Transcriptional regulator
GCK70_11860	COG1132	(ABC) transporter
GCK70_11915	COG3328	transposase activity
GCK70_11920	COG2223	nitrite transmembrane transporter activity
GCK70_11945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCK70_11970	COG3122	Protein conserved in bacteria
GCK70_11990	COG0534	Mate efflux family protein
GCK70_12010	COG4948	Mandelate Racemase Muconate Lactonizing
GCK70_12020	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_12025	COG3011	Protein conserved in bacteria
GCK70_12030	COG2271	Major facilitator Superfamily
GCK70_12035	COG1388	LysM domain
GCK70_12035	COG1470	cell adhesion involved in biofilm formation
GCK70_12040	COG3328	transposase activity
GCK70_12055	COG2925	Exonuclease
GCK70_12065	COG0531	amino acid
GCK70_12075	COG0371	Dehydrogenase
GCK70_12080	COG1129	ABC transporter
GCK70_12085	COG1129	ABC transporter
GCK70_12090	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_12095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_12110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCK70_12120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK70_12120	COG0131	Imidazoleglycerol-phosphate dehydratase
GCK70_12125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GCK70_12140	COG0140	phosphoribosyl-ATP diphosphatase activity
GCK70_12140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GCK70_12150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK70_12155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK70_12170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK70_12175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_12180	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_12185	COG1120	ATPase activity
GCK70_12200	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GCK70_12205	COG0076	glutamate decarboxylase activity
GCK70_12210	COG4114	ferric iron reductase
GCK70_12215	COG1253	flavin adenine dinucleotide binding
GCK70_12220	COG2982	Protein involved in outer membrane biogenesis
GCK70_12235	COG0489	protein tyrosine kinase activity
GCK70_12245	COG1943	Transposase
GCK70_12265	COG2814	Major facilitator Superfamily
GCK70_12275	COG1346	cytolysis
GCK70_12290	COG2949	membrane
GCK70_12295	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCK70_12310	COG2311	Membrane
GCK70_12320	COG0477	Major facilitator Superfamily
GCK70_12325	COG0583	DNA-binding transcription factor activity
GCK70_12355	COG1136	(ABC) transporter
GCK70_12365	COG0303	'Molybdopterin
GCK70_12375	COG3328	transposase activity
GCK70_12385	COG0488	(ABC) transporter
GCK70_12515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCK70_12520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCK70_12530	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_12535	COG1024	Enoyl-CoA hydratase
GCK70_12545	COG3425	synthase
GCK70_12550	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_12555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK70_12560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCK70_12570	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_12595	COG2920	part of a sulfur-relay system
GCK70_12615	COG1832	CoA-binding protein
GCK70_12620	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GCK70_12630	COG0210	DNA helicase
GCK70_12635	COG3304	Inner membrane component domain
GCK70_12640	COG1289	transmembrane transporter activity
GCK70_12645	COG3070	regulator of competence-specific genes
GCK70_12655	COG2885	chlorophyll binding
GCK70_12655	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK70_12660	COG1943	Transposase
GCK70_12670	COG1067	ATP-dependent peptidase activity
GCK70_12705	COG1943	Transposase
GCK70_12715	COG3130	regulation of translation
GCK70_12725	COG3009	Protein conserved in bacteria
GCK70_12735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK70_12735	COG3008	intermembrane lipid transfer
GCK70_12740	COG2995	paraquat-inducible protein a
GCK70_12755	COG3217	Mosc domain protein beta barrel domain protein
GCK70_12755	COG0633	Ferredoxin
GCK70_12770	COG0308	aminopeptidase N
GCK70_12790	COG1448	Aminotransferase
GCK70_12800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK70_12805	COG3108	Peptidase M15
GCK70_12810	COG2989	Protein conserved in bacteria
GCK70_12815	COG1943	Transposase
GCK70_12825	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GCK70_12830	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GCK70_12835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCK70_12850	COG3173	Aminoglycoside phosphotransferase
GCK70_12865	COG2835	tetraacyldisaccharide 4'-kinase activity
GCK70_12870	COG1278	Cold shock
GCK70_12880	COG5383	Protein conserved in bacteria
GCK70_12895	COG2333	competence protein COMEC
GCK70_12895	COG0658	competence protein
GCK70_12910	COG0539	negative regulation of cytoplasmic translation
GCK70_12935	COG5295	Hep Hag repeat protein
GCK70_12935	COG5295	Hep Hag repeat protein
GCK70_12940	COG0252	asparaginase activity
GCK70_12945	COG1944	ATP diphosphatase activity
GCK70_12950	COG2116	formate transmembrane transporter activity
GCK70_12955	COG1882	Formate acetyltransferase
GCK70_12965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCK70_12970	COG2814	Major facilitator Superfamily
GCK70_12980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCK70_12990	COG1674	ftsk spoiiie
GCK70_12990	COG3107	peptidoglycan biosynthetic process
GCK70_13000	COG0492	ferredoxin-NADP+ reductase activity
GCK70_13010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCK70_13020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCK70_13035	COG0542	response to heat
GCK70_13050	COG1278	Cold shock
GCK70_13060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_13065	COG2990	Protein conserved in bacteria
GCK70_13070	COG3593	DNA synthesis involved in DNA repair
GCK70_13075	COG2431	L-lysine efflux transmembrane transporter activity
GCK70_13085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_13090	COG0028	Belongs to the TPP enzyme family
GCK70_13100	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCK70_13105	COG0702	epimerase
GCK70_13110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_13120	COG1605	Chorismate mutase
GCK70_13125	COG1126	abc transporter atp-binding protein
GCK70_13130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_13135	COG4215	(ABC) transporter
GCK70_13140	COG4160	amino acid transport
GCK70_13160	COG1120	ATPase activity
GCK70_13165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_13170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_13195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_13210	COG1177	transmembrane transport
GCK70_13215	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK70_13220	COG3842	ATPase activity
GCK70_13225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCK70_13245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK70_13250	COG0569	domain protein
GCK70_13250	COG2985	domain, Protein
GCK70_13260	COG0671	phosphoesterase, PA-phosphatase related
GCK70_13265	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK70_13270	COG1349	DNA-binding transcription factor activity
GCK70_13275	COG0814	amino acid
GCK70_13280	COG1686	Belongs to the peptidase S11 family
GCK70_13285	COG2011	ABC-type metal ion transport system permease component
GCK70_13310	COG0625	glutathione transferase activity
GCK70_13320	COG4771	TonB-dependent receptor
GCK70_13330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_13340	COG0833	amino acid
GCK70_13345	COG0583	DNA-binding transcription factor activity
GCK70_13350	COG2855	membrane
GCK70_13360	COG3188	usher protein
GCK70_13365	COG3121	Chaperone
GCK70_13380	COG3710	Transcriptional regulator
GCK70_13385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_13385	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GCK70_13385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_13390	COG1105	Belongs to the carbohydrate kinase PfkB family
GCK70_13400	COG0494	nUDIX hydrolase
GCK70_13405	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_13410	COG1129	ABC transporter
GCK70_13420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCK70_13445	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_13465	COG1312	Catalyzes the dehydration of D-mannonate
GCK70_13470	COG0246	Mannitol dehydrogenase
GCK70_13475	COG2186	Transcriptional regulator
GCK70_13485	COG0523	cobalamin synthesis protein
GCK70_13490	COG0671	phosphoesterase, PA-phosphatase related
GCK70_13495	COG0791	NLP P60 protein
GCK70_13500	COG2200	EAL domain
GCK70_13505	COG4166	transmembrane transport
GCK70_13510	COG4174	ABC transporter (Permease)
GCK70_13515	COG4239	(ABC) transporter, permease
GCK70_13520	COG4172	Belongs to the ABC transporter superfamily
GCK70_13530	COG2814	Major facilitator Superfamily
GCK70_13535	COG1187	pseudouridine synthase activity
GCK70_13540	COG1061	Type III restriction enzyme res subunit
GCK70_13555	COG1943	Transposase
GCK70_13565	COG3082	Protein of unknown function (DUF1414)
GCK70_13570	COG3083	sulfuric ester hydrolase activity
GCK70_13590	COG3157	Type VI secretion system effector, Hcp
GCK70_13605	COG2723	6-phospho-beta-galactosidase activity
GCK70_13610	COG1737	Transcriptional regulator
GCK70_13630	COG3299	homolog of phage Mu protein gp47
GCK70_13670	COG4386	tail sheath protein
GCK70_13690	COG3622	Belongs to the hyi family
GCK70_13695	COG1349	DNA-binding transcription factor activity
GCK70_13700	COG0235	Class ii aldolase
GCK70_13705	COG3395	kinase activity
GCK70_13750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCK70_13775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GCK70_13780	COG2223	nitrite transmembrane transporter activity
GCK70_13785	COG2198	Histidine kinase
GCK70_13785	COG0642	Histidine kinase
GCK70_13790	COG0642	Histidine kinase
GCK70_13790	COG2198	Histidine kinase
GCK70_13800	COG2205	protein histidine kinase activity
GCK70_13800	COG0784	Response regulator, receiver
GCK70_13825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_13840	COG0814	amino acid
GCK70_13870	COG0697	spore germination
GCK70_13880	COG1982	Orn Lys Arg decarboxylase major
GCK70_13885	COG0531	amino acid
GCK70_13890	COG1174	glycine betaine transport
GCK70_13895	COG1125	glycine betaine transport
GCK70_13900	COG1174	glycine betaine transport
GCK70_13910	COG2897	thiosulfate sulfurtransferase activity
GCK70_13925	COG0410	ABC transporter
GCK70_13930	COG1122	ATPase activity
GCK70_13950	COG4807	Protein conserved in bacteria
GCK70_13965	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GCK70_13975	COG2261	transglycosylase associated protein
GCK70_13985	COG1403	HNH endonuclease
GCK70_13995	COG0277	FAD linked oxidase domain protein
GCK70_14000	COG1686	Belongs to the peptidase S11 family
GCK70_14010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK70_14035	COG3328	transposase activity
GCK70_14070	COG0513	Belongs to the DEAD box helicase family
GCK70_14075	COG1309	transcriptional regulator
GCK70_14085	COG1131	(ABC) transporter
GCK70_14090	COG0842	Transport permease protein
GCK70_14095	COG0842	Transport permease protein
GCK70_14115	COG1902	pentaerythritol trinitrate reductase activity
GCK70_14150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GCK70_14160	COG0583	DNA-binding transcription factor activity
GCK70_14165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK70_14185	COG1943	Transposase
GCK70_14190	COG0670	Belongs to the BI1 family
GCK70_14195	COG0314	molybdopterin synthase activity
GCK70_14200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GCK70_14210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GCK70_14215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GCK70_14220	COG4628	conserved protein (DUF2132)
GCK70_14225	COG0556	nucleotide-excision repair
GCK70_14235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK70_14240	COG2226	methyltransferase
GCK70_14265	COG0561	phosphatase activity
GCK70_14275	COG4149	molybdate abc transporter
GCK70_14280	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCK70_14290	COG2005	Transcriptional regulator
GCK70_14290	COG3585	molybdate ion transport
GCK70_14300	COG1119	ATPase activity
GCK70_14310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCK70_14315	COG1085	galactose-1-phosphate uridylyltransferase
GCK70_14330	COG2017	converts alpha-aldose to the beta-anomer
GCK70_14345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK70_14350	COG1230	cation diffusion facilitator family transporter
GCK70_14380	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GCK70_14385	COG2885	chlorophyll binding
GCK70_14395	COG3064	Membrane
GCK70_14395	COG3064	Membrane
GCK70_14400	COG0848	biopolymer transport protein
GCK70_14405	COG0811	peptide transport
GCK70_14410	COG0824	Thioesterase
GCK70_14415	COG3790	cyd operon protein YbgE
GCK70_14420	COG4890	Cyd operon protein YbgT
GCK70_14425	COG1294	oxidase, subunit
GCK70_14430	COG1271	oxidase subunit
GCK70_14435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCK70_14445	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK70_14450	COG0567	Dehydrogenase, E1 component
GCK70_14460	COG1053	succinate dehydrogenase
GCK70_14465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GCK70_14470	COG2009	succinate dehydrogenase
GCK70_14485	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GCK70_14490	COG0497	DNA recombination
GCK70_14495	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK70_14505	COG2867	negative regulation of translational initiation
GCK70_14530	COG0582	viral genome integration into host DNA
GCK70_14590	COG3657	addiction module killer protein
GCK70_14615	COG1953	Uracil, thiamine, allantoin
GCK70_14625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK70_14635	COG2226	methyltransferase
GCK70_14645	COG0741	lytic transglycosylase activity
GCK70_14645	COG1388	LysM domain
GCK70_14660	COG0656	L-ascorbic acid biosynthetic process
GCK70_14695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK70_14705	COG2011	ABC-type metal ion transport system permease component
GCK70_14710	COG1464	Belongs to the NlpA lipoprotein family
GCK70_14720	COG1720	tRNA m6t6A37 methyltransferase activity
GCK70_14730	COG3015	lipoprotein NlpE involved in copper resistance
GCK70_14740	COG4681	YaeQ
GCK70_14750	COG4568	rho-dependent transcription termination
GCK70_14760	COG0037	tRNA processing
GCK70_14765	COG0346	lactoylglutathione lyase activity
GCK70_14775	COG0587	DNA-directed DNA polymerase activity
GCK70_14785	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCK70_14805	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GCK70_14815	COG0750	zinc metalloprotease
GCK70_14820	COG0575	Belongs to the CDS family
GCK70_14825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GCK70_14860	COG0024	Methionine aminopeptidase
GCK70_14885	COG0564	pseudouridine synthase activity
GCK70_14890	COG3098	single-species biofilm formation
GCK70_14895	COG1943	Transposase
GCK70_14910	COG1611	Belongs to the LOG family
GCK70_14920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK70_14930	COG2363	Small membrane protein
GCK70_14935	COG0583	DNA-binding transcription factor activity
GCK70_14945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCK70_14950	COG2166	iron-sulfur cluster assembly
GCK70_14955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCK70_14960	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GCK70_14975	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK70_14985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GCK70_14990	COG1074	ATP-dependent DNA helicase activity
GCK70_15000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GCK70_15070	COG0667	Aldo Keto reductase
GCK70_15100	COG1609	Transcriptional regulator
GCK70_15105	COG0019	diaminopimelate decarboxylase activity
GCK70_15110	COG0583	DNA-binding transcription factor activity
GCK70_15115	COG2814	Major facilitator Superfamily
GCK70_15120	COG0583	DNA-binding transcription factor activity
GCK70_15135	COG0840	transmembrane signaling receptor activity
GCK70_15180	COG2165	general secretion pathway protein
GCK70_15230	COG0288	reversible hydration of carbon dioxide
GCK70_15270	COG1943	Transposase
GCK70_15275	COG3119	arylsulfatase activity
GCK70_15280	COG1349	DNA-binding transcription factor activity
GCK70_15290	COG2222	sugar isomerase
GCK70_15295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_15300	COG3715	PTS system
GCK70_15305	COG3716	PTS system mannose fructose sorbose family IID component
GCK70_15310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_15320	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_15330	COG0641	radical SAM
GCK70_15335	COG3119	arylsulfatase activity
GCK70_15345	COG0191	fructose-bisphosphate aldolase activity
GCK70_15365	COG2271	Major facilitator Superfamily
GCK70_15385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_15385	COG1263	PTS System
GCK70_15390	COG1874	Beta-galactosidase
GCK70_15395	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GCK70_15400	COG3833	ABC-type maltose transport systems, permease component
GCK70_15405	COG1175	transmembrane transport
GCK70_15410	COG2182	Extracellular solute-binding protein
GCK70_15420	COG1129	ABC transporter
GCK70_15425	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_15430	COG1879	ABC-type sugar transport system periplasmic component
GCK70_15440	COG0791	NLP P60 protein
GCK70_15445	COG1695	Transcriptional regulator
GCK70_15535	COG2944	sequence-specific DNA binding
GCK70_15560	COG0582	viral genome integration into host DNA
GCK70_15580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GCK70_15585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK70_15590	COG4974	Belongs to the 'phage' integrase family
GCK70_15595	COG0716	FMN binding
GCK70_15600	COG4452	Inner membrane protein CreD
GCK70_15605	COG2205	protein histidine kinase activity
GCK70_15610	COG0745	RESPONSE REGULATOR receiver
GCK70_15620	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GCK70_15635	COG1272	protein, Hemolysin III
GCK70_15680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK70_15685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK70_15690	COG0006	proline dipeptidase activity
GCK70_15710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCK70_15715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCK70_15720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GCK70_15750	COG0191	fructose-bisphosphate aldolase activity
GCK70_15785	COG2259	Doxx family
GCK70_15795	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GCK70_15800	COG4575	ribosome binding
GCK70_15820	COG0586	Pfam SNARE associated Golgi protein
GCK70_15835	COG2271	Major facilitator Superfamily
GCK70_15845	COG0246	Mannitol dehydrogenase
GCK70_15850	COG2721	sulfolactate sulfo-lyase activity
GCK70_15860	COG1943	Transposase
GCK70_15870	COG0673	inositol 2-dehydrogenase activity
GCK70_15875	COG1451	nucleotide metabolic process
GCK70_15890	COG1902	pentaerythritol trinitrate reductase activity
GCK70_15890	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCK70_15895	COG3247	response to pH
GCK70_15915	COG4245	von Willebrand factor, type A
GCK70_15930	COG4245	von Willebrand factor, type A
GCK70_15935	COG2831	hemolysin activation secretion protein
GCK70_15940	COG3210	domain, Protein
GCK70_15965	COG3210	domain, Protein
GCK70_15970	COG3210	domain, Protein
GCK70_15990	COG3842	ATPase activity
GCK70_15995	COG3459	Glycosyltransferase 36 associated
GCK70_16000	COG1609	Transcriptional regulator
GCK70_16005	COG1653	transport
GCK70_16015	COG0395	ABC-type sugar transport system, permease component
GCK70_16035	COG1289	transmembrane transporter activity
GCK70_16080	COG0251	oxidation-reduction process
GCK70_16150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCK70_16155	COG0358	DNA primase activity
GCK70_16180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GCK70_16195	COG4991	sh3 domain protein
GCK70_16200	COG3025	triphosphatase activity
GCK70_16215	COG0531	amino acid
GCK70_16235	COG3384	dioxygenase
GCK70_16240	COG0754	glutathionylspermidine amidase activity
GCK70_16255	COG1538	Outer membrane efflux protein
GCK70_16260	COG0494	nUDIX hydrolase
GCK70_16265	COG3151	Protein conserved in bacteria
GCK70_16270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCK70_16275	COG3150	esterase
GCK70_16280	COG0187	DNA topoisomerase II activity
GCK70_16285	COG0583	DNA-binding transcription factor activity
GCK70_16290	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK70_16300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GCK70_16305	COG0204	Acyl-transferase
GCK70_16315	COG2132	Multicopper oxidase
GCK70_16330	COG0656	L-ascorbic acid biosynthetic process
GCK70_16340	COG1979	alcohol dehydrogenase
GCK70_16345	COG2207	Transcriptional regulator
GCK70_16350	COG0586	Pfam SNARE associated Golgi protein
GCK70_16355	COG0626	cystathionine gamma-synthase activity
GCK70_16360	COG0811	peptide transport
GCK70_16365	COG0848	biopolymer transport protein
GCK70_16420	COG4964	Belongs to the GSP D family
GCK70_16425	COG4964	Belongs to the GSP D family
GCK70_16460	COG4592	Periplasmic binding protein
GCK70_16480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK70_16485	COG1684	flagellar biosynthetic protein fliR
GCK70_16490	COG1987	bacterial-type flagellum assembly
GCK70_16510	COG2204	response regulator
GCK70_16555	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GCK70_16560	COG1815	bacterial-type flagellum-dependent cell motility
GCK70_16565	COG1558	bacterial-type flagellum-dependent cell motility
GCK70_16570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK70_16575	COG1749	Flagellar hook protein flgE
GCK70_16580	COG4787	bacterial-type flagellum-dependent cell motility
GCK70_16585	COG4786	Flagellar basal body rod
GCK70_16590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GCK70_16595	COG1706	bacterial-type flagellum-dependent cell motility
GCK70_16605	COG1256	bacterial-type flagellum assembly
GCK70_16625	COG3710	Transcriptional regulator
GCK70_16645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GCK70_16670	COG1191	sigma factor activity
GCK70_16675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GCK70_16745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_16800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GCK70_16805	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK70_16810	COG4771	TonB-dependent receptor
GCK70_16830	COG2226	methyltransferase
GCK70_16830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK70_16830	COG3433	isochorismatase activity
GCK70_16835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK70_16870	COG1132	(ABC) transporter
GCK70_16885	COG2610	gluconate transmembrane transporter activity
GCK70_16895	COG3501	Rhs element vgr protein
GCK70_16905	COG3209	COG3209 Rhs family protein
GCK70_16925	COG0471	metal ion transport
GCK70_16945	COG2211	Major facilitator Superfamily
GCK70_16995	COG2771	luxR family
GCK70_17000	COG3916	Acyl-homoserine-lactone synthase
GCK70_17130	COG1982	Orn Lys Arg decarboxylase major
GCK70_17135	COG1879	ABC-type sugar transport system periplasmic component
GCK70_17140	COG1129	ABC transporter
GCK70_17145	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_17150	COG4774	siderophore transport
GCK70_17170	COG1194	a g-specific adenine glycosylase
GCK70_17180	COG3171	Protein conserved in bacteria
GCK70_17185	COG2066	Belongs to the glutaminase family
GCK70_17195	COG3064	Membrane
GCK70_17195	COG1073	alpha beta
GCK70_17195	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GCK70_17200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK70_17205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GCK70_17215	COG0762	integral membrane protein
GCK70_17225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCK70_17230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCK70_17235	COG2805	Type II/IV secretion system protein
GCK70_17245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK70_17260	COG0189	ligase activity
GCK70_17265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCK70_17270	COG2356	endonuclease I
GCK70_17285	COG1166	arginine decarboxylase activity
GCK70_17300	COG0501	Belongs to the peptidase M48B family
GCK70_17305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCK70_17325	COG0494	nUDIX hydrolase
GCK70_17355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCK70_17360	COG0849	cell division
GCK70_17365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GCK70_17385	COG0772	Belongs to the SEDS family
GCK70_17400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GCK70_17405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCK70_17410	COG0768	penicillin binding
GCK70_17415	COG3116	cell division
GCK70_17440	COG1609	Transcriptional regulator
GCK70_17450	COG1943	Transposase
GCK70_17460	COG0028	Belongs to the TPP enzyme family
GCK70_17470	COG1022	Amp-dependent synthetase and ligase
GCK70_17490	COG1943	Transposase
GCK70_17500	COG0473	3-isopropylmalate dehydrogenase activity
GCK70_17515	COG2814	Major facilitator Superfamily
GCK70_17530	COG4143	(ABC) transporter
GCK70_17535	COG1178	ABC-type Fe3 transport system permease component
GCK70_17545	COG0586	Pfam SNARE associated Golgi protein
GCK70_17550	COG0417	DNA replication proofreading
GCK70_17570	COG3047	cAMP biosynthetic process
GCK70_17570	COG2885	chlorophyll binding
GCK70_17605	COG3501	Rhs element vgr protein
GCK70_17655	COG0564	pseudouridine synthase activity
GCK70_17660	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GCK70_17670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK70_17675	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GCK70_17705	COG1943	Transposase
GCK70_17710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCK70_17720	COG2966	Psort location CytoplasmicMembrane, score
GCK70_17725	COG1280	lysine exporter protein (LysE YggA)
GCK70_17730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GCK70_17735	COG0505	Belongs to the CarA family
GCK70_17745	COG1943	Transposase
GCK70_17755	COG1047	Peptidyl-prolyl cis-trans
GCK70_17770	COG0196	riboflavin kinase activity
GCK70_17790	COG0583	DNA-binding transcription factor activity
GCK70_17810	COG1584	GPR1 FUN34 yaaH family protein
GCK70_17825	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCK70_17865	COG0745	RESPONSE REGULATOR receiver
GCK70_17870	COG3045	CreA protein
GCK70_17880	COG3708	Transcriptional regulator
GCK70_17880	COG2207	Transcriptional regulator
GCK70_17895	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GCK70_17900	COG0741	lytic transglycosylase activity
GCK70_17915	COG2199	diguanylate cyclase activity
GCK70_17920	COG2885	chlorophyll binding
GCK70_17945	COG0560	Phosphoserine phosphatase
GCK70_17950	COG3726	membrane protein affecting hemolysin expression
GCK70_17970	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK70_17975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK70_17980	COG0084	hydrolase, TatD family'
GCK70_17985	COG4667	esterase of the alpha-beta hydrolase superfamily
GCK70_17995	COG2823	Periplasmic or secreted lipoprotein
GCK70_18005	COG0456	acetyltransferase
GCK70_18010	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GCK70_18030	COG3706	GGDEF domain
GCK70_18055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_18060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_18075	COG0859	PFAM glycosyl transferase family 9
GCK70_18130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_18130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_18130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK70_18135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_18140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_18145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_18150	COG2207	Transcriptional regulator
GCK70_18160	COG4269	membrane
GCK70_18220	COG1401	restriction endodeoxyribonuclease activity
GCK70_18240	COG0583	DNA-binding transcription factor activity
GCK70_18245	COG1741	Belongs to the pirin family
GCK70_18255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GCK70_18275	COG2823	Periplasmic or secreted lipoprotein
GCK70_18285	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GCK70_18295	COG5002	protein histidine kinase activity
GCK70_18295	COG2198	Histidine kinase
GCK70_18295	COG0784	Response regulator, receiver
GCK70_18305	COG1242	4 iron, 4 sulfur cluster binding
GCK70_18310	COG0070	glutamate synthase
GCK70_18310	COG0069	glutamate synthase activity
GCK70_18310	COG0067	glutamate synthase
GCK70_18315	COG0493	'glutamate synthase
GCK70_18325	COG2969	positive regulation of protein catabolic process
GCK70_18330	COG0625	glutathione transferase activity
GCK70_18350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GCK70_18355	COG3105	Protein conserved in bacteria
GCK70_18360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK70_18365	COG1943	Transposase
GCK70_18370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK70_18380	COG5007	Belongs to the BolA IbaG family
GCK70_18385	COG3113	response to antibiotic
GCK70_18390	COG2854	intermembrane phospholipid transfer
GCK70_18395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK70_18400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCK70_18405	COG1127	ABC transporter
GCK70_18410	COG0530	calcium, potassium:sodium antiporter activity
GCK70_18415	COG0517	IMP dehydrogenase activity
GCK70_18415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GCK70_18420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GCK70_18425	COG3117	lipopolysaccharide transmembrane transporter activity
GCK70_18430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GCK70_18435	COG1137	ATPase activity
GCK70_18440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GCK70_18450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_18465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_18495	COG1609	Transcriptional regulator
GCK70_18500	COG1263	PTS System
GCK70_18500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_18505	COG0366	Alpha amylase catalytic
GCK70_18510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK70_18515	COG3783	Cytochrome b(562)
GCK70_18525	COG0312	modulator of DNA gyrase
GCK70_18535	COG2732	(Barnase) inhibitor
GCK70_18565	COG0583	DNA-binding transcription factor activity
GCK70_18615	COG0312	modulator of DNA gyrase
GCK70_18620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK70_18625	COG3164	Protein of unknown function
GCK70_18630	COG1530	ribonuclease E activity
GCK70_18640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GCK70_18645	COG1792	Involved in formation and maintenance of cell shape
GCK70_18650	COG1077	Cell shape determining protein MreB Mrl
GCK70_18655	COG2200	EAL domain
GCK70_18655	COG2199	diguanylate cyclase activity
GCK70_18660	COG0604	alcohol dehydrogenase
GCK70_18665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCK70_18680	COG0511	ligase activity, forming carbon-carbon bonds
GCK70_18685	COG0439	Biotin carboxylase
GCK70_18690	COG3924	membrane
GCK70_18695	COG4145	pantothenate transmembrane transporter activity
GCK70_18705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK70_18710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GCK70_18740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK70_18750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK70_18755	COG3133	Outer membrane lipoprotein
GCK70_18765	COG1278	Cold shock
GCK70_18770	COG1278	Cold shock
GCK70_18790	COG0625	glutathione transferase activity
GCK70_18800	COG1069	ribulokinase activity
GCK70_18810	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_18815	COG1129	ABC transporter
GCK70_18825	COG1560	Kdo2-lipid A biosynthetic process
GCK70_18835	COG0025	NhaP-type Na H and K H
GCK70_18840	COG2252	PERMEase
GCK70_18845	COG3077	Addiction module antitoxin, RelB DinJ family
GCK70_18860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK70_18870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK70_18875	COG0431	NADPH-dependent FMN reductase
GCK70_18885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_18890	COG1869	D-ribose catabolic process
GCK70_18895	COG2207	Transcriptional regulator
GCK70_18895	COG1917	Cupin 2, conserved barrel domain protein
GCK70_18900	COG0673	inositol 2-dehydrogenase activity
GCK70_18920	COG3209	COG3209 Rhs family protein
GCK70_18935	COG3501	Rhs element vgr protein
GCK70_18965	COG3209	COG3209 Rhs family protein
GCK70_19080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK70_19085	COG0058	SHG alpha-glucan phosphorylase activity
GCK70_19110	COG3275	phosphorelay sensor kinase activity
GCK70_19140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK70_19145	COG2095	MarC family integral membrane protein
GCK70_19165	COG3265	gluconokinase activity
GCK70_19170	COG2610	gluconate transmembrane transporter activity
GCK70_19175	COG1609	Transcriptional regulator
GCK70_19180	COG1741	Belongs to the pirin family
GCK70_19195	COG0745	RESPONSE REGULATOR receiver
GCK70_19205	COG0191	fructose-bisphosphate aldolase activity
GCK70_19215	COG1879	ABC-type sugar transport system periplasmic component
GCK70_19220	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_19235	COG2081	HI0933 family
GCK70_19240	COG0306	phosphate transporter
GCK70_19255	COG0589	response to stress
GCK70_19275	COG0339	signal peptide processing
GCK70_19280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GCK70_19285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK70_19290	COG3835	regulator
GCK70_19300	COG2610	gluconate transmembrane transporter activity
GCK70_19305	COG1929	Belongs to the glycerate kinase type-1 family
GCK70_19330	COG1295	ribonuclease BN
GCK70_19335	COG2134	cdp-diacylglycerol pyrophosphatase
GCK70_19340	COG2982	Protein involved in outer membrane biogenesis
GCK70_19345	COG2200	EAL domain
GCK70_19350	COG1942	4-Oxalocrotonate Tautomerase
GCK70_19355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_19360	COG0612	Peptidase, M16
GCK70_19380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK70_19385	COG2199	diguanylate cyclase activity
GCK70_19385	COG2200	EAL domain
GCK70_19390	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK70_19395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK70_19400	COG4608	Belongs to the ABC transporter superfamily
GCK70_19405	COG0444	Belongs to the ABC transporter superfamily
GCK70_19410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_19415	COG0601	transmembrane transport
GCK70_19420	COG0747	negative chemotaxis
GCK70_19430	COG2831	hemolysin activation secretion protein
GCK70_19445	COG2271	Major facilitator Superfamily
GCK70_19470	COG2197	response regulator
GCK70_19475	COG2194	sulfuric ester hydrolase activity
GCK70_19490	COG2986	histidine ammonia-lyase
GCK70_19505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GCK70_19520	COG4607	ABC-type enterochelin transport system periplasmic component
GCK70_19530	COG4605	iron ion homeostasis
GCK70_19535	COG4604	ABC transporter, ATP-binding protein
GCK70_19585	COG0582	viral genome integration into host DNA
GCK70_19595	COG2207	Transcriptional regulator
GCK70_19595	COG1609	Transcriptional regulator
GCK70_19600	COG4214	carbohydrate transport
GCK70_19610	COG4213	ABC transporter substrate-binding protein
GCK70_19620	COG1070	Carbohydrate kinase
GCK70_19630	COG3121	Chaperone
GCK70_19645	COG3274	enterobacterial common antigen metabolic process
GCK70_19715	COG1175	transmembrane transport
GCK70_19720	COG3833	ABC-type maltose transport systems, permease component
GCK70_19735	COG0527	aspartate kinase activity
GCK70_19765	COG2224	Isocitrate lyase
GCK70_19770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GCK70_19830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCK70_19845	COG0551	DNA topoisomerase type I activity
GCK70_19855	COG0758	DNA mediated transformation
GCK70_19875	COG0569	domain protein
GCK70_19885	COG3036	rescue of stalled ribosome
GCK70_19890	COG0789	Transcriptional regulator
GCK70_19905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GCK70_19920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK70_19925	COG0201	protein transport
GCK70_19935	COG1841	ribosomal large subunit assembly
GCK70_19975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GCK70_19980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GCK70_19990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCK70_19995	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GCK70_20005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GCK70_20030	COG0051	transcription antitermination factor activity, RNA binding
GCK70_20050	COG1943	Transposase
GCK70_20065	COG0049	tRNA binding
GCK70_20070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GCK70_20090	COG2964	Protein conserved in bacteria
GCK70_20095	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK70_20110	COG1047	Peptidyl-prolyl cis-trans
GCK70_20115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GCK70_20125	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK70_20135	COG1216	Glycosyl transferase, family 2
GCK70_20145	COG2175	clavaminate synthase activity
GCK70_20150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK70_20160	COG4521	taurine ABC transporter
GCK70_20170	COG0429	hydrolase of the alpha beta-hydrolase fold
GCK70_20180	COG3954	Phosphoribulokinase
GCK70_20190	COG1765	OsmC-like protein
GCK70_20200	COG1289	transmembrane transporter activity
GCK70_20215	COG0433	COG0433 Predicted ATPase
GCK70_20220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK70_20225	COG1486	melibiose metabolic process
GCK70_20245	COG0402	S-adenosylhomocysteine deaminase activity
GCK70_20250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCK70_20255	COG2146	nitrite reductase [NAD(P)H] activity
GCK70_20270	COG0180	Tryptophanyl-tRNA synthetase
GCK70_20275	COG0546	phosphoglycolate phosphatase activity
GCK70_20280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCK70_20305	COG4796	Type ii and iii secretion system protein
GCK70_20335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GCK70_20340	COG0494	nUDIX hydrolase
GCK70_20350	COG1011	Hydrolase
GCK70_20355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GCK70_20375	COG0745	RESPONSE REGULATOR receiver
GCK70_20380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK70_20385	COG2183	response to ionizing radiation
GCK70_20390	COG1918	ferrous iron import across plasma membrane
GCK70_20425	COG1640	4-alpha-glucanotransferase
GCK70_20430	COG0058	SHG alpha-glucan phosphorylase activity
GCK70_20435	COG0058	SHG alpha-glucan phosphorylase activity
GCK70_20455	COG1349	DNA-binding transcription factor activity
GCK70_20475	COG0527	aspartate kinase activity
GCK70_20475	COG0460	homoserine dehydrogenase
GCK70_20490	COG4682	membrane
GCK70_20500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCK70_20510	COG1609	Transcriptional regulator
GCK70_20515	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK70_20530	COG1575	Belongs to the MenA family. Type 1 subfamily
GCK70_20590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GCK70_20595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK70_20600	COG1494	fructose-1,6-bisphosphatase
GCK70_20610	COG3152	Membrane
GCK70_20625	COG0583	DNA-binding transcription factor activity
GCK70_20630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCK70_20635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCK70_20640	COG0471	metal ion transport
GCK70_20650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GCK70_20680	COG3678	ATP-independent chaperone mediated protein folding
GCK70_20685	COG0745	RESPONSE REGULATOR receiver
GCK70_20690	COG2205	protein histidine kinase activity
GCK70_20695	COG2169	Transcriptional regulator
GCK70_20695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK70_20700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCK70_20705	COG1045	serine acetyltransferase
GCK70_20725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK70_20730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCK70_20740	COG4942	peptidase
GCK70_20755	COG0156	8-amino-7-oxononanoate synthase activity
GCK70_20765	COG0859	PFAM glycosyl transferase family 9
GCK70_20770	COG0859	PFAM glycosyl transferase family 9
GCK70_20775	COG1519	Transferase
GCK70_20795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GCK70_20815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCK70_20840	COG1561	YicC-like family, N-terminal region
GCK70_20845	COG2860	membrane
GCK70_20850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GCK70_20865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK70_20870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK70_20875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK70_20885	COG0786	glutamate:sodium symporter activity
GCK70_20890	COG2233	PERMEase
GCK70_20895	COG2982	Protein involved in outer membrane biogenesis
GCK70_20900	COG0456	acetyltransferase
GCK70_20920	COG1295	ribonuclease BN
GCK70_20925	COG1011	Hydrolase
GCK70_20935	COG0174	glutamine synthetase
GCK70_20940	COG3852	Histidine kinase
GCK70_20950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK70_20975	COG1943	Transposase
GCK70_20980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK70_20980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK70_20985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK70_20990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCK70_20995	COG3084	Protein conserved in bacteria
GCK70_21005	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCK70_21010	COG3328	transposase activity
GCK70_21040	COG2186	Transcriptional regulator
GCK70_21045	COG0477	Major facilitator Superfamily
GCK70_21060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_21090	COG1522	sequence-specific DNA binding
GCK70_21095	COG0716	FMN binding
GCK70_21115	COG3312	ion transport
GCK70_21170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GCK70_21175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCK70_21180	COG0573	inorganic phosphate transmembrane transporter activity
GCK70_21185	COG0581	inorganic phosphate transmembrane transporter activity
GCK70_21195	COG0704	Plays a role in the regulation of phosphate uptake
GCK70_21205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_21210	COG0765	amino acid transport
GCK70_21215	COG0765	amino acid transport
GCK70_21220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_21230	COG2252	PERMEase
GCK70_21260	COG0706	membrane insertase activity
GCK70_21275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GCK70_21340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GCK70_21350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK70_21470	COG1475	DNA binding
GCK70_21570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK70_21580	COG3344	reverse transcriptase
GCK70_21605	COG3328	transposase activity
GCK70_21645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GCK70_21690	COG3941	tape measure
GCK70_21785	COG1475	DNA binding
GCK70_21790	COG1475	DNA binding
GCK70_21795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK70_21885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK70_21935	COG0515	serine threonine protein kinase
GCK70_21975	COG5599	Phosphatase
GCK70_21980	COG1317	bacterial-type flagellum organization
GCK70_21990	COG4669	(LipO)protein
GCK70_22040	COG2207	Transcriptional regulator
GCK70_22050	COG4792	protein secretion
GCK70_22055	COG4791	protein targeting
GCK70_22060	COG4794	Type iii secretion
GCK70_22065	COG4790	Type iii secretion
GCK70_22070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GCK70_22115	COG4789	Type iii secretion
GCK70_22135	COG0457	Tetratricopeptide repeat
GCK70_22160	COG4886	Leucine-rich repeat (LRR) protein
GCK70_22170	COG3328	transposase activity
GCK70_22195	COG3177	Filamentation induced by cAMP protein fic
GCK70_22230	COG1192	Involved in chromosome partitioning
GCK70_22235	COG1475	DNA binding
GCK70_22250	COG3609	addiction module antidote protein, CC2985 family
GCK70_22260	COG5599	Phosphatase
GCK70_22470	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK70_22480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GCK70_22530	COG2161	toxin-antitoxin pair type II binding
GCK70_22535	COG4115	mRNA cleavage
GCK70_22600	COG3567	Phage-associated protein, HI1409 family
GCK70_22645	COG4683	PFAM Phage derived protein Gp49-like (DUF891)