locus-tag	class	description
BZ15_1	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BZ15_10	COG0697	spore germination
BZ15_100	COG3725	Membrane protein required for beta-lactamase induction
BZ15_1000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ15_1003	COG0129	dihydroxy-acid dehydratase activity
BZ15_1005	COG4575	ribosome binding
BZ15_1007	COG1169	isochorismate synthase
BZ15_101	COG1113	amino acid transport
BZ15_1010	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BZ15_1013	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZ15_1019	COG1126	abc transporter atp-binding protein
BZ15_102	COG2186	Transcriptional regulator
BZ15_1020	COG0765	amino acid transport
BZ15_1021	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ15_1027	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZ15_103	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BZ15_1031	COG1063	alcohol dehydrogenase
BZ15_1032	COG1879	ABC-type sugar transport system periplasmic component
BZ15_1033	COG1129	ABC transporter
BZ15_1034	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_1035	COG1609	Transcriptional regulator
BZ15_1036	COG0583	DNA-binding transcription factor activity
BZ15_1037	COG0473	3-isopropylmalate dehydrogenase activity
BZ15_1038	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ15_1039	COG4638	Rieske (2fe-2S)
BZ15_104	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ15_1040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ15_1041	COG2831	hemolysin activation secretion protein
BZ15_1042	COG3210	domain, Protein
BZ15_1045	COG3210	domain, Protein
BZ15_1048	COG3210	domain, Protein
BZ15_105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ15_1050	COG3842	ATPase activity
BZ15_1052	COG1609	Transcriptional regulator
BZ15_1055	COG0395	ABC-type sugar transport system, permease component
BZ15_1056	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BZ15_106	COG1943	Transposase
BZ15_1060	COG0668	transmembrane transport
BZ15_1061	COG1518	maintenance of DNA repeat elements
BZ15_1062	COG1203	CRISPR-associated helicase, Cas3
BZ15_1067	COG0667	Aldo Keto reductase
BZ15_1069	COG0477	Major facilitator Superfamily
BZ15_107	COG1049	propionate catabolic process, 2-methylcitrate cycle
BZ15_1071	COG0583	DNA-binding transcription factor activity
BZ15_1072	COG3916	Acyl-homoserine-lactone synthase
BZ15_1073	COG2771	luxR family
BZ15_1077	COG0628	permease
BZ15_1080	COG3328	transposase activity
BZ15_1081	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ15_1084	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ15_1085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ15_1086	COG1121	(ABC) transporter
BZ15_1087	COG0803	Belongs to the bacterial solute-binding protein 9 family
BZ15_109	COG0697	spore germination
BZ15_1091	COG4249	Peptidase C14 caspase catalytic subunit p20
BZ15_1096	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BZ15_1097	COG0072	phenylalanine-tRNA ligase activity
BZ15_1097	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZ15_1098	COG0776	regulation of translation
BZ15_1101	COG0386	Belongs to the glutathione peroxidase family
BZ15_1102	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BZ15_1110	COG0791	NLP P60 protein
BZ15_1116	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ15_1116	COG0574	Belongs to the PEP-utilizing enzyme family
BZ15_1117	COG0628	permease
BZ15_1118	COG0247	lactate metabolic process
BZ15_1118	COG0277	FAD linked oxidase domain protein
BZ15_1119	COG2050	protein possibly involved in aromatic compounds catabolism
BZ15_1120	COG0316	Belongs to the HesB IscA family
BZ15_1121	COG0719	Fe-S assembly protein
BZ15_1122	COG0396	ATPase activity
BZ15_1123	COG0719	Fe-S assembly protein
BZ15_1126	COG1376	ErfK ybiS ycfS ynhG family protein
BZ15_1126	COG1388	LysM domain
BZ15_1129	COG1943	Transposase
BZ15_113	COG2132	Multicopper oxidase
BZ15_1130	COG4238	major outer membrane lipoprotein
BZ15_1135	COG0307	riboflavin synthase, alpha
BZ15_1136	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BZ15_1137	COG2814	Major facilitator Superfamily
BZ15_1138	COG0583	DNA-binding transcription factor activity
BZ15_114	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BZ15_1141	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ15_1142	COG0791	NLP P60 protein
BZ15_1144	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZ15_1145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BZ15_1146	COG0346	lactoylglutathione lyase activity
BZ15_1148	COG1902	pentaerythritol trinitrate reductase activity
BZ15_1149	COG1309	transcriptional regulator
BZ15_115	COG0288	reversible hydration of carbon dioxide
BZ15_1150	COG2194	sulfuric ester hydrolase activity
BZ15_1151	COG3313	Fe-S protein
BZ15_1152	COG4989	oxidoreductase activity
BZ15_1154	COG3133	Outer membrane lipoprotein
BZ15_1156	COG3895	Periplasmic Protein
BZ15_116	COG1131	(ABC) transporter
BZ15_1160	COG0625	glutathione transferase activity
BZ15_1165	COG3104	oligopeptide transport
BZ15_1167	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ15_1167	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ15_1168	COG4172	Belongs to the ABC transporter superfamily
BZ15_117	COG0842	Transport permease protein
BZ15_1170	COG4171	peptide transport system, permease
BZ15_1171	COG4168	peptide transport system, permease
BZ15_1172	COG4166	transmembrane transport
BZ15_1173	COG1943	Transposase
BZ15_1174	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BZ15_1175	COG1842	Phage shock protein A
BZ15_1177	COG1983	PspC domain protein
BZ15_1179	COG3106	COG3106 Predicted ATPase
BZ15_118	COG0726	polysaccharide deacetylase
BZ15_1184	COG1943	Transposase
BZ15_1185	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BZ15_1186	COG4948	Mandelate Racemase Muconate Lactonizing
BZ15_1187	COG2866	Carboxypeptidase
BZ15_1188	COG4166	transmembrane transport
BZ15_1191	COG0657	acetylesterase activity
BZ15_1191	COG2755	lipolytic protein G-D-S-L family
BZ15_1194	COG0674	pyruvate-flavodoxin oxidoreductase activity
BZ15_1194	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ15_1194	COG1013	pyruvate-flavodoxin oxidoreductase activity
BZ15_1194	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BZ15_1196	COG1285	pathogenesis
BZ15_1197	COG3042	response to heat
BZ15_1198	COG3187	Heat shock protein
BZ15_1199	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ15_12	COG0642	Histidine kinase
BZ15_1200	COG2911	Protein conserved in bacteria
BZ15_1202	COG3784	Protein of unknown function (DUF1318)
BZ15_1203	COG0246	Mannitol dehydrogenase
BZ15_1204	COG2390	Transcriptional regulator
BZ15_1206	COG1643	Atp-dependent helicase
BZ15_1209	COG3591	Belongs to the peptidase S1B family
BZ15_1211	COG3038	cytochrome b561
BZ15_1215	COG1943	Transposase
BZ15_1216	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BZ15_1217	COG2205	protein histidine kinase activity
BZ15_1218	COG0745	RESPONSE REGULATOR receiver
BZ15_122	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BZ15_1220	COG0531	amino acid
BZ15_1222	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BZ15_1223	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BZ15_1224	COG0589	response to stress
BZ15_1225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZ15_1226	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ15_123	COG0617	tRNA 3'-terminal CCA addition
BZ15_1230	COG1011	Hydrolase
BZ15_1231	COG0440	acetolactate synthase activity
BZ15_1232	COG0028	Belongs to the TPP enzyme family
BZ15_1237	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BZ15_1238	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ15_1239	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ15_124	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BZ15_1240	COG1879	ABC-type sugar transport system periplasmic component
BZ15_1242	COG1609	Transcriptional regulator
BZ15_1246	COG4128	Pfam Zonular occludens toxin
BZ15_125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BZ15_1260	COG4128	Pfam Zonular occludens toxin
BZ15_127	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BZ15_1270	COG0038	chloride channel
BZ15_1271	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZ15_1273	COG1940	carbohydrate kinase activity
BZ15_1274	COG0583	DNA-binding transcription factor activity
BZ15_1275	COG2814	Major facilitator Superfamily
BZ15_1277	COG0114	fumarate hydratase activity
BZ15_1279	COG5339	Protein conserved in bacteria
BZ15_128	COG1643	Atp-dependent helicase
BZ15_1281	COG0385	Bile acid
BZ15_1282	COG0673	inositol 2-dehydrogenase activity
BZ15_1284	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_1286	COG1879	ABC-type sugar transport system periplasmic component
BZ15_129	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZ15_1290	COG2274	protein secretion by the type I secretion system
BZ15_1291	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ15_1298	COG2207	Transcriptional regulator
BZ15_1298	COG3708	Transcriptional regulator
BZ15_1299	COG4658	electron transport chain
BZ15_13	COG0745	RESPONSE REGULATOR receiver
BZ15_130	COG1120	ATPase activity
BZ15_1300	COG4659	FMN binding
BZ15_1302	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BZ15_1303	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ15_1304	COG2271	Major facilitator Superfamily
BZ15_1306	COG1966	Carbon starvation protein
BZ15_1307	COG2879	small protein
BZ15_1308	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZ15_131	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ15_1312	COG0023	Translation Initiation Factor
BZ15_1315	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BZ15_1316	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BZ15_1317	COG0671	phosphoesterase, PA-phosphatase related
BZ15_1318	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZ15_1319	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZ15_132	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ15_1321	COG0583	DNA-binding transcription factor activity
BZ15_1322	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZ15_1325	COG0616	signal peptide processing
BZ15_1326	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_1328	COG1187	pseudouridine synthase activity
BZ15_1329	COG0009	L-threonylcarbamoyladenylate synthase
BZ15_1332	COG0512	Glutamine amidotransferase of anthranilate synthase
BZ15_1334	COG0134	indole-3-glycerol-phosphate synthase activity
BZ15_1334	COG0135	phosphoribosylanthranilate isomerase activity
BZ15_1338	COG3047	cAMP biosynthetic process
BZ15_1343	COG1607	acyl-coa hydrolase
BZ15_1344	COG3328	transposase activity
BZ15_1345	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BZ15_1346	COG2350	Protein conserved in bacteria
BZ15_1353	COG4608	Belongs to the ABC transporter superfamily
BZ15_1354	COG0444	Belongs to the ABC transporter superfamily
BZ15_1355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ15_1356	COG0601	transmembrane transport
BZ15_1358	COG2095	MarC family integral membrane protein
BZ15_1359	COG1454	alcohol dehydrogenase
BZ15_1359	COG1012	belongs to the aldehyde dehydrogenase family
BZ15_136	COG2860	membrane
BZ15_1362	COG1435	thymidine kinase activity
BZ15_1365	COG0745	RESPONSE REGULATOR receiver
BZ15_1367	COG3328	transposase activity
BZ15_1368	COG0788	formyltetrahydrofolate deformylase activity
BZ15_1371	COG0583	DNA-binding transcription factor activity
BZ15_1372	COG0708	Exodeoxyribonuclease III
BZ15_1373	COG0494	nUDIX hydrolase
BZ15_1375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZ15_1376	COG0709	Synthesizes selenophosphate from selenide and ATP
BZ15_1377	COG0778	Nitroreductase
BZ15_1378	COG0616	signal peptide processing
BZ15_1379	COG0252	asparaginase activity
BZ15_138	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BZ15_1380	COG1335	isochorismatase
BZ15_1381	COG3139	Protein of unknown function (DUF1315)
BZ15_1385	COG3713	MltA-interacting MipA family protein
BZ15_1386	COG2766	serine protein kinase
BZ15_1389	COG0583	DNA-binding transcription factor activity
BZ15_1391	COG2814	Major facilitator Superfamily
BZ15_1393	COG2719	SpoVR family
BZ15_1399	COG1104	cysteine desulfurase activity
BZ15_14	COG2027	D-alanyl-D-alanine carboxypeptidase
BZ15_140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ15_1401	COG3328	transposase activity
BZ15_141	COG4999	Histidine kinase
BZ15_141	COG3850	Histidine kinase
BZ15_141	COG2205	protein histidine kinase activity
BZ15_141	COG3437	response regulator, receiver
BZ15_1417	COG1943	Transposase
BZ15_142	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ15_143	COG3956	TIGRFAM MazG family protein
BZ15_1433	COG3328	transposase activity
BZ15_1453	COG0582	viral genome integration into host DNA
BZ15_1455	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZ15_1456	COG2951	lytic endotransglycosylase activity
BZ15_1459	COG2894	cell division
BZ15_1460	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BZ15_1461	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BZ15_1462	COG0318	PFAM AMP-dependent synthetase and ligase
BZ15_1463	COG3065	identical protein binding
BZ15_1465	COG1199	ATP-dependent helicase activity
BZ15_1466	COG0251	oxidation-reduction process
BZ15_1469	COG0800	Aldolase
BZ15_147	COG0602	queuosine metabolic process
BZ15_1471	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZ15_1472	COG1737	Transcriptional regulator
BZ15_1473	COG0469	pyruvate kinase activity
BZ15_1474	COG1560	Kdo2-lipid A biosynthetic process
BZ15_1475	COG0739	heme binding
BZ15_1476	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BZ15_1478	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ15_148	COG0720	synthase
BZ15_1483	COG0494	nUDIX hydrolase
BZ15_1485	COG1801	Protein of unknown function DUF72
BZ15_1486	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BZ15_1490	COG3102	Protein conserved in bacteria
BZ15_1494	COG0728	peptidoglycan biosynthetic process
BZ15_1495	COG0673	inositol 2-dehydrogenase activity
BZ15_1496	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ15_1499	COG3381	protein complex oligomerization
BZ15_15	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ15_1502	COG1940	carbohydrate kinase activity
BZ15_1503	COG0584	glycerophosphoryl diester phosphodiesterase
BZ15_1504	COG3842	ATPase activity
BZ15_1505	COG1943	Transposase
BZ15_1507	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ15_1508	COG3833	ABC-type maltose transport systems, permease component
BZ15_1512	COG0659	secondary active sulfate transmembrane transporter activity
BZ15_1515	COG0659	secondary active sulfate transmembrane transporter activity
BZ15_1516	COG1943	Transposase
BZ15_1518	COG2912	Transglutaminase-like superfamily
BZ15_1519	COG3094	Invasion gene expression up-regulator, SirB
BZ15_1520	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ15_1525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZ15_1528	COG0012	GTP binding
BZ15_1539	COG5002	protein histidine kinase activity
BZ15_1548	COG0500	methyltransferase
BZ15_1553	COG3328	transposase activity
BZ15_1562	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ15_1563	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BZ15_1564	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BZ15_1567	COG0402	S-adenosylhomocysteine deaminase activity
BZ15_1582	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ15_1583	COG3850	Histidine kinase
BZ15_1584	COG0387	Pfam Sodium calcium exchanger
BZ15_1585	COG1702	phosphate starvation-inducible protein PhoH
BZ15_1588	COG3658	cytochrome
BZ15_1589	COG1215	transferase activity, transferring glycosyl groups
BZ15_159	COG0529	Catalyzes the synthesis of activated sulfate
BZ15_1590	COG1649	PFAM Uncharacterised BCR, COG1649
BZ15_1590	COG0726	polysaccharide deacetylase
BZ15_1591	COG0457	Tetratricopeptide repeat
BZ15_1592	COG0006	proline dipeptidase activity
BZ15_1596	COG1136	(ABC) transporter
BZ15_1596	COG0577	efflux transmembrane transporter activity
BZ15_1598	COG0577	efflux transmembrane transporter activity
BZ15_1598	COG1136	(ABC) transporter
BZ15_16	COG1534	Rna-binding protein
BZ15_1601	COG0672	)-iron permease
BZ15_1603	COG2066	Belongs to the glutaminase family
BZ15_1604	COG1349	DNA-binding transcription factor activity
BZ15_1606	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ15_1607	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ15_1615	COG2030	dehydratase
BZ15_1616	COG0427	acetyl-CoA hydrolase
BZ15_162	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BZ15_1623	COG3188	usher protein
BZ15_1625	COG3121	Chaperone
BZ15_1627	COG0582	viral genome integration into host DNA
BZ15_1628	COG1169	isochorismate synthase
BZ15_1629	COG2814	Major facilitator Superfamily
BZ15_1630	COG1132	(ABC) transporter
BZ15_1633	COG3433	isochorismatase activity
BZ15_1633	COG2226	methyltransferase
BZ15_1633	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ15_1637	COG1021	2,3-dihydroxybenzoate-AMP ligase
BZ15_1638	COG4771	TonB-dependent receptor
BZ15_1651	COG0395	ABC-type sugar transport system, permease component
BZ15_1652	COG1175	transmembrane transport
BZ15_1654	COG0673	inositol 2-dehydrogenase activity
BZ15_1661	COG3328	transposase activity
BZ15_1662	COG3328	transposase activity
BZ15_167	COG4942	peptidase
BZ15_167	COG1388	LysM domain
BZ15_168	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ15_1685	COG2197	response regulator
BZ15_1687	COG3136	membrane protein required for alginate biosynthesis
BZ15_169	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BZ15_1691	COG1113	amino acid transport
BZ15_1694	COG2837	iron assimilation
BZ15_1699	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ15_1699	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ15_1699	COG0506	proline dehydrogenase activity
BZ15_170	COG0698	ribose 5-phosphate isomerase
BZ15_1705	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BZ15_1707	COG1191	sigma factor activity
BZ15_171	COG1063	alcohol dehydrogenase
BZ15_1713	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BZ15_1714	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BZ15_1715	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BZ15_1718	COG1677	Flagellar hook-basal body complex protein FliE
BZ15_172	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_1720	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZ15_1722	COG1157	protein secretion by the type III secretion system
BZ15_1723	COG2882	bacterial-type flagellum organization
BZ15_1725	COG1580	Controls the rotational direction of flagella during chemotaxis
BZ15_173	COG2376	Dihydroxyacetone kinase
BZ15_1730	COG1987	bacterial-type flagellum assembly
BZ15_1734	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ15_1735	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_1736	COG1129	ABC transporter
BZ15_1738	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_1739	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_1739	COG3347	Dehydrogenase
BZ15_1740	COG2390	Transcriptional regulator
BZ15_1742	COG1256	bacterial-type flagellum assembly
BZ15_1746	COG4786	Flagellar basal body rod
BZ15_1748	COG1749	Flagellar hook protein flgE
BZ15_1749	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZ15_1750	COG1558	bacterial-type flagellum-dependent cell motility
BZ15_1751	COG1815	bacterial-type flagellum-dependent cell motility
BZ15_1753	COG2747	anti-sigma28 factor FlgM
BZ15_1754	COG3418	PFAM FlgN family protein
BZ15_1756	COG1943	Transposase
BZ15_1759	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ15_176	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BZ15_1760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ15_1765	COG2372	response to copper ion
BZ15_1766	COG1528	Iron-storage protein
BZ15_1769	COG1770	oligopeptidase
BZ15_1772	COG3141	response to X-ray
BZ15_1773	COG0513	Belongs to the DEAD box helicase family
BZ15_1778	COG1760	l-serine dehydratase
BZ15_1779	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BZ15_1780	COG2368	4-hydroxyphenylacetate
BZ15_1783	COG3971	2-oxopent-4-enoate hydratase activity
BZ15_1785	COG3384	dioxygenase
BZ15_1786	COG1012	belongs to the aldehyde dehydrogenase family
BZ15_1789	COG1846	Transcriptional regulator
BZ15_1790	COG1253	flavin adenine dinucleotide binding
BZ15_1791	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ15_1791	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_1792	COG3715	PTS system
BZ15_1793	COG3716	PTS system mannose fructose sorbose family IID component
BZ15_1797	COG5002	protein histidine kinase activity
BZ15_1797	COG3447	MASE1 domain protein
BZ15_1797	COG5001	Diguanylate cyclase
BZ15_1799	COG2226	methyltransferase
BZ15_18	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZ15_180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ15_1801	COG1278	Cold shock
BZ15_1804	COG1113	amino acid transport
BZ15_181	COG1858	cytochrome C peroxidase
BZ15_1811	COG2207	Transcriptional regulator
BZ15_1813	COG1132	(ABC) transporter
BZ15_1822	COG3328	transposase activity
BZ15_1823	COG1917	Cupin 2, conserved barrel domain protein
BZ15_1825	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_1827	COG1175	transmembrane transport
BZ15_1828	COG0395	ABC-type sugar transport system, permease component
BZ15_1829	COG3842	ATPase activity
BZ15_183	COG4771	TonB-dependent receptor
BZ15_1830	COG1653	transport
BZ15_1831	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ15_1832	COG1988	membrane-bound metal-dependent
BZ15_1834	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ15_1836	COG0823	Involved in the tonB-independent uptake of proteins
BZ15_1837	COG2814	Major facilitator Superfamily
BZ15_1838	COG3121	Chaperone
BZ15_1841	COG3121	Chaperone
BZ15_1842	COG3539	Fimbrial protein
BZ15_1845	COG0793	Belongs to the peptidase S41A family
BZ15_1847	COG1956	GAF domain-containing protein
BZ15_1848	COG2995	paraquat-inducible protein a
BZ15_1849	COG3008	intermembrane lipid transfer
BZ15_1853	COG3121	Chaperone
BZ15_186	COG0024	Methionine aminopeptidase
BZ15_1865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZ15_1868	COG5295	Hep Hag repeat protein
BZ15_1870	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ15_1871	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BZ15_1872	COG0745	RESPONSE REGULATOR receiver
BZ15_1874	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BZ15_1877	COG0840	transmembrane signaling receptor activity
BZ15_188	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ15_188	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ15_1881	COG2964	Protein conserved in bacteria
BZ15_1883	COG0251	oxidation-reduction process
BZ15_1884	COG2271	Major facilitator Superfamily
BZ15_1885	COG0835	chemotaxis
BZ15_1886	COG2198	Histidine kinase
BZ15_1886	COG0643	Histidine kinase
BZ15_1887	COG1360	Flagellar Motor Protein
BZ15_189	COG1070	Carbohydrate kinase
BZ15_1892	COG1285	pathogenesis
BZ15_1893	COG0840	transmembrane signaling receptor activity
BZ15_1894	COG0840	transmembrane signaling receptor activity
BZ15_1896	COG1278	Cold shock
BZ15_1898	COG0604	alcohol dehydrogenase
BZ15_1898	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_1898	COG3321	synthase
BZ15_19	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BZ15_190	COG3623	hexulose-6-phosphate isomerase
BZ15_1900	COG1522	sequence-specific DNA binding
BZ15_1905	COG1733	regulation of RNA biosynthetic process
BZ15_1906	COG0702	epimerase
BZ15_1907	COG0840	transmembrane signaling receptor activity
BZ15_191	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_1910	COG0538	isocitrate dehydrogenase activity
BZ15_1911	COG1187	pseudouridine synthase activity
BZ15_1915	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BZ15_1917	COG0745	RESPONSE REGULATOR receiver
BZ15_1919	COG2850	peptidyl-arginine hydroxylation
BZ15_192	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_1921	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZ15_1923	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ15_1925	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ15_1926	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BZ15_1927	COG3134	Outer membrane lipoprotein
BZ15_193	COG1129	ABC transporter
BZ15_1930	COG3328	transposase activity
BZ15_1931	COG1530	ribonuclease E activity
BZ15_1932	COG0564	pseudouridine synthase activity
BZ15_1933	COG1943	Transposase
BZ15_1935	COG1399	metal-binding, possibly nucleic acid-binding protein
BZ15_1936	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BZ15_194	COG1943	Transposase
BZ15_1940	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_1942	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ15_1943	COG1943	Transposase
BZ15_1944	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ15_1945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BZ15_1947	COG0470	DNA polymerase III
BZ15_1948	COG0084	hydrolase, TatD family'
BZ15_1949	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ15_1949	COG1263	PTS System
BZ15_1950	COG1943	Transposase
BZ15_1951	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BZ15_1952	COG0537	adenosine 5'-monophosphoramidase activity
BZ15_1953	COG5633	Lipoprotein
BZ15_1956	COG1472	Belongs to the glycosyl hydrolase 3 family
BZ15_1958	COG1252	NADH dehydrogenase
BZ15_196	COG1349	DNA-binding transcription factor activity
BZ15_1961	COG3328	transposase activity
BZ15_1962	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BZ15_1965	COG3328	transposase activity
BZ15_1967	COG2223	nitrite transmembrane transporter activity
BZ15_197	COG0235	Class ii aldolase
BZ15_1972	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BZ15_1977	COG3122	Protein conserved in bacteria
BZ15_198	COG0243	molybdopterin cofactor binding
BZ15_1981	COG0534	Mate efflux family protein
BZ15_1985	COG4948	Mandelate Racemase Muconate Lactonizing
BZ15_1987	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_1988	COG3011	Protein conserved in bacteria
BZ15_1989	COG2271	Major facilitator Superfamily
BZ15_199	COG0437	4 iron, 4 sulfur cluster binding
BZ15_1990	COG3328	transposase activity
BZ15_1991	COG1470	cell adhesion involved in biofilm formation
BZ15_1991	COG1388	LysM domain
BZ15_1994	COG2925	Exonuclease
BZ15_1995	COG0531	amino acid
BZ15_1997	COG0371	Dehydrogenase
BZ15_1998	COG1129	ABC transporter
BZ15_1999	COG1129	ABC transporter
BZ15_200	COG3302	dmso reductase anchor subunit
BZ15_2000	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_2002	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ15_2004	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BZ15_2006	COG0131	Imidazoleglycerol-phosphate dehydratase
BZ15_2006	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZ15_2007	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BZ15_201	COG3381	protein complex oligomerization
BZ15_2010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BZ15_2010	COG0140	phosphoribosyl-ATP diphosphatase activity
BZ15_2012	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ15_2013	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ15_2016	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ15_2017	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ15_2018	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ15_2019	COG1120	ATPase activity
BZ15_202	COG3038	cytochrome b561
BZ15_2022	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BZ15_2023	COG0076	glutamate decarboxylase activity
BZ15_2024	COG4114	ferric iron reductase
BZ15_2025	COG1253	flavin adenine dinucleotide binding
BZ15_2026	COG2982	Protein involved in outer membrane biogenesis
BZ15_2029	COG0489	protein tyrosine kinase activity
BZ15_203	COG3783	Cytochrome b(562)
BZ15_2031	COG1943	Transposase
BZ15_2038	COG2814	Major facilitator Superfamily
BZ15_2040	COG1346	cytolysis
BZ15_2043	COG2949	membrane
BZ15_2044	COG4211	Belongs to the binding-protein-dependent transport system permease family
BZ15_2047	COG2311	Membrane
BZ15_2049	COG0477	Major facilitator Superfamily
BZ15_2050	COG0583	DNA-binding transcription factor activity
BZ15_2056	COG1136	(ABC) transporter
BZ15_2058	COG0303	'Molybdopterin
BZ15_2060	COG3328	transposase activity
BZ15_2062	COG0488	(ABC) transporter
BZ15_207	COG1129	ABC transporter
BZ15_208	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_2089	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BZ15_209	COG3959	Transketolase, thiamine diphosphate binding domain
BZ15_2090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZ15_2092	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_2093	COG1024	Enoyl-CoA hydratase
BZ15_2095	COG3425	synthase
BZ15_2096	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_2097	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ15_2098	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BZ15_21	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ15_210	COG3958	Transketolase
BZ15_2100	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_2107	COG2920	part of a sulfur-relay system
BZ15_211	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ15_2111	COG1832	CoA-binding protein
BZ15_2112	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BZ15_2114	COG0210	DNA helicase
BZ15_2115	COG3304	Inner membrane component domain
BZ15_2116	COG1289	transmembrane transporter activity
BZ15_2117	COG3070	regulator of competence-specific genes
BZ15_2119	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZ15_2119	COG2885	chlorophyll binding
BZ15_2120	COG1943	Transposase
BZ15_2122	COG1067	ATP-dependent peptidase activity
BZ15_2125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ15_2128	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ15_2129	COG1943	Transposase
BZ15_2130	COG3009	Protein conserved in bacteria
BZ15_2131	COG3008	intermembrane lipid transfer
BZ15_2131	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ15_2132	COG2995	paraquat-inducible protein a
BZ15_2133	COG0488	(ABC) transporter
BZ15_2135	COG0633	Ferredoxin
BZ15_2135	COG3217	Mosc domain protein beta barrel domain protein
BZ15_2138	COG0308	aminopeptidase N
BZ15_2142	COG1448	Aminotransferase
BZ15_2143	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ15_2144	COG3108	Peptidase M15
BZ15_2145	COG2989	Protein conserved in bacteria
BZ15_2146	COG1943	Transposase
BZ15_2148	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BZ15_2149	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BZ15_2150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BZ15_2151	COG3173	Aminoglycoside phosphotransferase
BZ15_2153	COG2835	tetraacyldisaccharide 4'-kinase activity
BZ15_2154	COG1278	Cold shock
BZ15_2155	COG5383	Protein conserved in bacteria
BZ15_2158	COG2333	competence protein COMEC
BZ15_2158	COG0658	competence protein
BZ15_2161	COG0539	negative regulation of cytoplasmic translation
BZ15_2166	COG5295	Hep Hag repeat protein
BZ15_2166	COG5295	Hep Hag repeat protein
BZ15_2167	COG0252	asparaginase activity
BZ15_2168	COG1944	ATP diphosphatase activity
BZ15_2169	COG2116	formate transmembrane transporter activity
BZ15_2170	COG1882	Formate acetyltransferase
BZ15_2172	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZ15_2173	COG2814	Major facilitator Superfamily
BZ15_2175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZ15_2178	COG3107	peptidoglycan biosynthetic process
BZ15_2178	COG1674	ftsk spoiiie
BZ15_218	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BZ15_2180	COG0492	ferredoxin-NADP+ reductase activity
BZ15_2182	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BZ15_2184	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BZ15_2185	COG1943	Transposase
BZ15_2186	COG0542	response to heat
BZ15_2188	COG1278	Cold shock
BZ15_219	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BZ15_2190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ15_2191	COG2990	Protein conserved in bacteria
BZ15_2192	COG3593	DNA synthesis involved in DNA repair
BZ15_2193	COG2431	L-lysine efflux transmembrane transporter activity
BZ15_2195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ15_2196	COG0028	Belongs to the TPP enzyme family
BZ15_2197	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BZ15_2198	COG0702	epimerase
BZ15_2199	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ15_2201	COG1605	Chorismate mutase
BZ15_2202	COG1126	abc transporter atp-binding protein
BZ15_2203	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ15_2204	COG4215	(ABC) transporter
BZ15_2205	COG4160	amino acid transport
BZ15_2209	COG1120	ATPase activity
BZ15_2210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ15_2215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ15_2218	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ15_2221	COG1177	transmembrane transport
BZ15_2222	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ15_2223	COG3842	ATPase activity
BZ15_2224	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BZ15_2227	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ15_2228	COG2985	domain, Protein
BZ15_2228	COG0569	domain protein
BZ15_2230	COG0671	phosphoesterase, PA-phosphatase related
BZ15_2231	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ15_2232	COG1349	DNA-binding transcription factor activity
BZ15_2233	COG0814	amino acid
BZ15_2234	COG1686	Belongs to the peptidase S11 family
BZ15_2235	COG2011	ABC-type metal ion transport system permease component
BZ15_224	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ15_2240	COG0625	glutathione transferase activity
BZ15_2241	COG4771	TonB-dependent receptor
BZ15_2243	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ15_2245	COG0833	amino acid
BZ15_2247	COG0583	DNA-binding transcription factor activity
BZ15_2248	COG2855	membrane
BZ15_225	COG1238	metal cluster binding
BZ15_2250	COG3188	usher protein
BZ15_2251	COG3121	Chaperone
BZ15_2254	COG3710	Transcriptional regulator
BZ15_2255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ15_2255	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BZ15_2255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ15_2256	COG1105	Belongs to the carbohydrate kinase PfkB family
BZ15_2258	COG0494	nUDIX hydrolase
BZ15_2259	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_226	COG2918	glutathione biosynthetic process
BZ15_2260	COG1129	ABC transporter
BZ15_2262	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BZ15_2267	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_2271	COG1312	Catalyzes the dehydration of D-mannonate
BZ15_2272	COG0246	Mannitol dehydrogenase
BZ15_2273	COG2186	Transcriptional regulator
BZ15_2275	COG0523	cobalamin synthesis protein
BZ15_2276	COG0671	phosphoesterase, PA-phosphatase related
BZ15_2277	COG0791	NLP P60 protein
BZ15_2279	COG2200	EAL domain
BZ15_228	COG1943	Transposase
BZ15_2280	COG4166	transmembrane transport
BZ15_2281	COG4174	ABC transporter (Permease)
BZ15_2282	COG4239	(ABC) transporter, permease
BZ15_2283	COG4172	Belongs to the ABC transporter superfamily
BZ15_2285	COG2814	Major facilitator Superfamily
BZ15_2286	COG1187	pseudouridine synthase activity
BZ15_2287	COG1061	Type III restriction enzyme res subunit
BZ15_2289	COG1943	Transposase
BZ15_229	COG1943	Transposase
BZ15_2291	COG3082	Protein of unknown function (DUF1414)
BZ15_2292	COG3083	sulfuric ester hydrolase activity
BZ15_2295	COG3157	Type VI secretion system effector, Hcp
BZ15_2299	COG2723	6-phospho-beta-galactosidase activity
BZ15_230	COG4536	flavin adenine dinucleotide binding
BZ15_2301	COG1737	Transcriptional regulator
BZ15_2305	COG3299	homolog of phage Mu protein gp47
BZ15_231	COG4137	Cytochrome C assembly protein
BZ15_2313	COG4386	tail sheath protein
BZ15_2317	COG3622	Belongs to the hyi family
BZ15_2318	COG1349	DNA-binding transcription factor activity
BZ15_2319	COG0235	Class ii aldolase
BZ15_232	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZ15_2320	COG3395	kinase activity
BZ15_2329	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BZ15_2332	COG1943	Transposase
BZ15_2333	COG1943	Transposase
BZ15_2334	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZ15_2336	COG2223	nitrite transmembrane transporter activity
BZ15_2337	COG0642	Histidine kinase
BZ15_2337	COG2198	Histidine kinase
BZ15_2338	COG2198	Histidine kinase
BZ15_2338	COG0642	Histidine kinase
BZ15_2340	COG0784	Response regulator, receiver
BZ15_2340	COG2205	protein histidine kinase activity
BZ15_2345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ15_2348	COG0814	amino acid
BZ15_2353	COG0697	spore germination
BZ15_2355	COG1982	Orn Lys Arg decarboxylase major
BZ15_2356	COG0531	amino acid
BZ15_2357	COG1174	glycine betaine transport
BZ15_2358	COG1125	glycine betaine transport
BZ15_2359	COG1174	glycine betaine transport
BZ15_2362	COG2897	thiosulfate sulfurtransferase activity
BZ15_2365	COG0410	ABC transporter
BZ15_2366	COG1122	ATPase activity
BZ15_237	COG1943	Transposase
BZ15_2370	COG4807	Protein conserved in bacteria
BZ15_2373	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BZ15_2375	COG2261	transglycosylase associated protein
BZ15_2377	COG1403	HNH endonuclease
BZ15_2379	COG0277	FAD linked oxidase domain protein
BZ15_238	COG3137	Salt-induced outer membrane protein
BZ15_2380	COG1686	Belongs to the peptidase S11 family
BZ15_2382	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ15_2384	COG1943	Transposase
BZ15_2385	COG2211	Major facilitator Superfamily
BZ15_2386	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BZ15_2388	COG0583	DNA-binding transcription factor activity
BZ15_2389	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ15_239	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ15_2393	COG1943	Transposase
BZ15_2394	COG0670	Belongs to the BI1 family
BZ15_2395	COG0314	molybdopterin synthase activity
BZ15_2396	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BZ15_2398	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BZ15_240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ15_2400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BZ15_2401	COG4628	conserved protein (DUF2132)
BZ15_2402	COG0556	nucleotide-excision repair
BZ15_2404	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZ15_2405	COG2226	methyltransferase
BZ15_241	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ15_2410	COG0561	phosphatase activity
BZ15_2412	COG4149	molybdate abc transporter
BZ15_2413	COG0725	ABC transporter, periplasmic molybdate-binding protein
BZ15_2415	COG3585	molybdate ion transport
BZ15_2415	COG2005	Transcriptional regulator
BZ15_2416	COG1119	ATPase activity
BZ15_2419	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BZ15_242	COG3279	Response regulator of the LytR AlgR family
BZ15_2420	COG1085	galactose-1-phosphate uridylyltransferase
BZ15_2423	COG2017	converts alpha-aldose to the beta-anomer
BZ15_2428	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ15_243	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ15_2430	COG1230	cation diffusion facilitator family transporter
BZ15_2436	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BZ15_2437	COG2885	chlorophyll binding
BZ15_2439	COG3064	Membrane
BZ15_2439	COG3064	Membrane
BZ15_244	COG1605	Chorismate mutase
BZ15_244	COG0287	Prephenate dehydrogenase
BZ15_2440	COG0848	biopolymer transport protein
BZ15_2441	COG0811	peptide transport
BZ15_2442	COG0824	Thioesterase
BZ15_2443	COG3790	cyd operon protein YbgE
BZ15_2444	COG4890	Cyd operon protein YbgT
BZ15_2445	COG1294	oxidase, subunit
BZ15_2446	COG1271	oxidase subunit
BZ15_2447	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZ15_2449	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ15_245	COG0077	Prephenate dehydratase
BZ15_245	COG1605	Chorismate mutase
BZ15_2450	COG0567	Dehydrogenase, E1 component
BZ15_2452	COG1053	succinate dehydrogenase
BZ15_2453	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BZ15_2454	COG2009	succinate dehydrogenase
BZ15_2457	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BZ15_2458	COG0497	DNA recombination
BZ15_2459	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ15_2461	COG2867	negative regulation of translational initiation
BZ15_2463	COG1943	Transposase
BZ15_2464	COG0582	viral genome integration into host DNA
BZ15_2474	COG3657	addiction module killer protein
BZ15_248	COG0077	Prephenate dehydratase
BZ15_248	COG1605	Chorismate mutase
BZ15_2480	COG1953	Uracil, thiamine, allantoin
BZ15_2482	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BZ15_2484	COG2226	methyltransferase
BZ15_2486	COG0741	lytic transglycosylase activity
BZ15_2486	COG1388	LysM domain
BZ15_2489	COG0656	L-ascorbic acid biosynthetic process
BZ15_249	COG1943	Transposase
BZ15_2495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZ15_2497	COG2011	ABC-type metal ion transport system permease component
BZ15_2498	COG1464	Belongs to the NlpA lipoprotein family
BZ15_25	COG0195	Participates in both transcription termination and antitermination
BZ15_250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BZ15_2500	COG1720	tRNA m6t6A37 methyltransferase activity
BZ15_2502	COG3015	lipoprotein NlpE involved in copper resistance
BZ15_2504	COG4681	YaeQ
BZ15_2506	COG4568	rho-dependent transcription termination
BZ15_2508	COG0037	tRNA processing
BZ15_2509	COG0346	lactoylglutathione lyase activity
BZ15_251	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ15_2511	COG0587	DNA-directed DNA polymerase activity
BZ15_2513	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BZ15_2517	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BZ15_2519	COG0750	zinc metalloprotease
BZ15_252	COG0564	pseudouridine synthase activity
BZ15_2520	COG0575	Belongs to the CDS family
BZ15_2521	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZ15_2527	COG0024	Methionine aminopeptidase
BZ15_2532	COG0564	pseudouridine synthase activity
BZ15_2533	COG3098	single-species biofilm formation
BZ15_2534	COG1943	Transposase
BZ15_2537	COG1611	Belongs to the LOG family
BZ15_2538	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ15_254	COG0542	response to heat
BZ15_2540	COG2363	Small membrane protein
BZ15_2541	COG0583	DNA-binding transcription factor activity
BZ15_2543	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BZ15_2544	COG2166	iron-sulfur cluster assembly
BZ15_2545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BZ15_2546	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BZ15_2549	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ15_2551	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZ15_2552	COG1074	ATP-dependent DNA helicase activity
BZ15_2554	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BZ15_2563	COG4771	TonB-dependent receptor
BZ15_2564	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ15_2565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BZ15_2573	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ15_2575	COG5001	Diguanylate cyclase
BZ15_2575	COG3300	MHYT domain
BZ15_2576	COG2801	Transposase and inactivated derivatives
BZ15_2578	COG2211	Major facilitator Superfamily
BZ15_2588	COG3916	Acyl-homoserine-lactone synthase
BZ15_2589	COG2771	luxR family
BZ15_261	COG5544	Lipoprotein
BZ15_2610	COG1662	PFAM IS1 transposase
BZ15_2614	COG1982	Orn Lys Arg decarboxylase major
BZ15_2615	COG1879	ABC-type sugar transport system periplasmic component
BZ15_2616	COG1129	ABC transporter
BZ15_2617	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_2618	COG4774	siderophore transport
BZ15_262	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZ15_2622	COG1194	a g-specific adenine glycosylase
BZ15_2624	COG3171	Protein conserved in bacteria
BZ15_2625	COG2066	Belongs to the glutaminase family
BZ15_2628	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BZ15_2628	COG1073	alpha beta
BZ15_2628	COG3064	Membrane
BZ15_2629	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ15_263	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ15_263	COG0045	succinate-CoA ligase (ADP-forming) activity
BZ15_263	COG1042	CoA-binding domain protein
BZ15_2630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BZ15_2632	COG0762	integral membrane protein
BZ15_2633	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BZ15_2634	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BZ15_2635	COG2805	Type II/IV secretion system protein
BZ15_2637	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ15_2640	COG0189	ligase activity
BZ15_2641	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BZ15_2642	COG2356	endonuclease I
BZ15_2643	COG3091	SprT-like family
BZ15_2646	COG1166	arginine decarboxylase activity
BZ15_2648	COG0501	Belongs to the peptidase M48B family
BZ15_2649	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZ15_265	COG3118	belongs to the thioredoxin family
BZ15_2656	COG0191	fructose-bisphosphate aldolase activity
BZ15_266	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ15_2661	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BZ15_2662	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BZ15_2663	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZ15_2666	COG0006	proline dipeptidase activity
BZ15_2667	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ15_2668	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ15_267	COG2814	Major facilitator Superfamily
BZ15_2674	COG5295	Hep Hag repeat protein
BZ15_2676	COG1272	protein, Hemolysin III
BZ15_2679	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BZ15_268	COG1566	PFAM secretion protein HlyD family protein
BZ15_2680	COG0745	RESPONSE REGULATOR receiver
BZ15_2681	COG2205	protein histidine kinase activity
BZ15_2682	COG4452	Inner membrane protein CreD
BZ15_2683	COG0716	FMN binding
BZ15_2684	COG4974	Belongs to the 'phage' integrase family
BZ15_2685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ15_2686	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BZ15_269	COG1846	Transcriptional regulator
BZ15_2690	COG0582	viral genome integration into host DNA
BZ15_2695	COG2944	sequence-specific DNA binding
BZ15_271	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BZ15_2712	COG1695	Transcriptional regulator
BZ15_2713	COG0791	NLP P60 protein
BZ15_2715	COG1879	ABC-type sugar transport system periplasmic component
BZ15_2716	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_2717	COG1129	ABC transporter
BZ15_2719	COG2182	Extracellular solute-binding protein
BZ15_272	COG2814	Major facilitator Superfamily
BZ15_2720	COG1175	transmembrane transport
BZ15_2721	COG3833	ABC-type maltose transport systems, permease component
BZ15_2722	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BZ15_2723	COG1874	Beta-galactosidase
BZ15_2724	COG1263	PTS System
BZ15_2724	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ15_2728	COG2271	Major facilitator Superfamily
BZ15_2732	COG0191	fructose-bisphosphate aldolase activity
BZ15_2734	COG3119	arylsulfatase activity
BZ15_2735	COG0641	radical SAM
BZ15_2737	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_2739	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_2740	COG3716	PTS system mannose fructose sorbose family IID component
BZ15_2741	COG3715	PTS system
BZ15_2742	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ15_2743	COG2222	sugar isomerase
BZ15_2745	COG1349	DNA-binding transcription factor activity
BZ15_2746	COG3119	arylsulfatase activity
BZ15_2754	COG0288	reversible hydration of carbon dioxide
BZ15_2773	COG0840	transmembrane signaling receptor activity
BZ15_2775	COG0583	DNA-binding transcription factor activity
BZ15_2776	COG0583	DNA-binding transcription factor activity
BZ15_2777	COG2814	Major facilitator Superfamily
BZ15_2778	COG1609	Transcriptional regulator
BZ15_2779	COG0019	diaminopimelate decarboxylase activity
BZ15_2785	COG0667	Aldo Keto reductase
BZ15_2796	COG2226	methyltransferase
BZ15_2796	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ15_2796	COG3433	isochorismatase activity
BZ15_2797	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ15_2798	COG3433	isochorismatase activity
BZ15_2798	COG2226	methyltransferase
BZ15_2798	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ15_2804	COG1132	(ABC) transporter
BZ15_2808	COG2610	gluconate transmembrane transporter activity
BZ15_281	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BZ15_2811	COG3501	Rhs element vgr protein
BZ15_2813	COG3209	COG3209 Rhs family protein
BZ15_2816	COG0471	metal ion transport
BZ15_2818	COG2801	Transposase and inactivated derivatives
BZ15_2821	COG3133	Outer membrane lipoprotein
BZ15_2822	COG3133	Outer membrane lipoprotein
BZ15_2827	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BZ15_2828	COG1191	sigma factor activity
BZ15_2833	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BZ15_2837	COG3710	Transcriptional regulator
BZ15_284	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BZ15_2841	COG1256	bacterial-type flagellum assembly
BZ15_2843	COG1706	bacterial-type flagellum-dependent cell motility
BZ15_2844	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BZ15_2845	COG4786	Flagellar basal body rod
BZ15_2847	COG1943	Transposase
BZ15_2849	COG1749	Flagellar hook protein flgE
BZ15_2850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZ15_2851	COG1558	bacterial-type flagellum-dependent cell motility
BZ15_2852	COG1815	bacterial-type flagellum-dependent cell motility
BZ15_2853	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BZ15_2862	COG2204	response regulator
BZ15_2866	COG1987	bacterial-type flagellum assembly
BZ15_2867	COG1684	flagellar biosynthetic protein fliR
BZ15_2868	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ15_2873	COG4592	Periplasmic binding protein
BZ15_2877	COG1943	Transposase
BZ15_2878	COG1943	Transposase
BZ15_288	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BZ15_2881	COG4964	Belongs to the GSP D family
BZ15_2882	COG4964	Belongs to the GSP D family
BZ15_2892	COG0848	biopolymer transport protein
BZ15_2894	COG0811	peptide transport
BZ15_2895	COG0626	cystathionine gamma-synthase activity
BZ15_2896	COG0586	Pfam SNARE associated Golgi protein
BZ15_2897	COG2207	Transcriptional regulator
BZ15_2898	COG1979	alcohol dehydrogenase
BZ15_2899	COG0656	L-ascorbic acid biosynthetic process
BZ15_290	COG1960	acyl-CoA dehydrogenase activity
BZ15_2902	COG2132	Multicopper oxidase
BZ15_2903	COG0204	Acyl-transferase
BZ15_2904	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZ15_2905	COG2249	NAD(P)H dehydrogenase (quinone) activity
BZ15_2906	COG0583	DNA-binding transcription factor activity
BZ15_2907	COG0187	DNA topoisomerase II activity
BZ15_2908	COG3150	esterase
BZ15_2909	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BZ15_2910	COG3151	Protein conserved in bacteria
BZ15_2911	COG0494	nUDIX hydrolase
BZ15_2912	COG1538	Outer membrane efflux protein
BZ15_2915	COG0754	glutathionylspermidine amidase activity
BZ15_2916	COG3384	dioxygenase
BZ15_292	COG3034	peptidoglycan biosynthetic process
BZ15_2920	COG0531	amino acid
BZ15_2923	COG3025	triphosphatase activity
BZ15_2924	COG4991	sh3 domain protein
BZ15_2927	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BZ15_293	COG0121	glutamine amidotransferase
BZ15_2931	COG0358	DNA primase activity
BZ15_2932	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ15_294	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ15_295	COG1805	sodium ion transport
BZ15_2950	COG0251	oxidation-reduction process
BZ15_2958	COG1289	transmembrane transporter activity
BZ15_296	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ15_2962	COG0395	ABC-type sugar transport system, permease component
BZ15_2964	COG1653	transport
BZ15_2965	COG1609	Transcriptional regulator
BZ15_2966	COG3459	Glycosyltransferase 36 associated
BZ15_2967	COG3842	ATPase activity
BZ15_2971	COG3210	domain, Protein
BZ15_2973	COG3210	domain, Protein
BZ15_2975	COG3210	domain, Protein
BZ15_2976	COG2831	hemolysin activation secretion protein
BZ15_2977	COG4245	von Willebrand factor, type A
BZ15_2980	COG4245	von Willebrand factor, type A
BZ15_2983	COG3247	response to pH
BZ15_2984	COG0446	pyridine nucleotide-disulphide oxidoreductase
BZ15_2984	COG1902	pentaerythritol trinitrate reductase activity
BZ15_2987	COG1451	nucleotide metabolic process
BZ15_2988	COG0673	inositol 2-dehydrogenase activity
BZ15_2991	COG1943	Transposase
BZ15_2993	COG2721	sulfolactate sulfo-lyase activity
BZ15_2994	COG0246	Mannitol dehydrogenase
BZ15_2996	COG2271	Major facilitator Superfamily
BZ15_2999	COG0586	Pfam SNARE associated Golgi protein
BZ15_300	COG1477	protein flavinylation
BZ15_3002	COG4575	ribosome binding
BZ15_3003	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BZ15_3005	COG2259	Doxx family
BZ15_3006	COG0435	Glutathione S-transferase
BZ15_3009	COG0494	nUDIX hydrolase
BZ15_3014	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BZ15_3015	COG0849	cell division
BZ15_3016	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BZ15_3020	COG0772	Belongs to the SEDS family
BZ15_3023	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BZ15_3024	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BZ15_3025	COG0768	penicillin binding
BZ15_3026	COG3116	cell division
BZ15_3030	COG1609	Transcriptional regulator
BZ15_3032	COG0028	Belongs to the TPP enzyme family
BZ15_3033	COG1022	Amp-dependent synthetase and ligase
BZ15_3036	COG1943	Transposase
BZ15_3038	COG0473	3-isopropylmalate dehydrogenase activity
BZ15_304	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ15_3041	COG2814	Major facilitator Superfamily
BZ15_3045	COG2814	Major facilitator Superfamily
BZ15_3048	COG4143	(ABC) transporter
BZ15_3049	COG1178	ABC-type Fe3 transport system permease component
BZ15_3051	COG0586	Pfam SNARE associated Golgi protein
BZ15_3052	COG0417	DNA replication proofreading
BZ15_3056	COG2885	chlorophyll binding
BZ15_3056	COG3047	cAMP biosynthetic process
BZ15_3064	COG3501	Rhs element vgr protein
BZ15_3074	COG0564	pseudouridine synthase activity
BZ15_3075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BZ15_3077	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ15_3078	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BZ15_3083	COG1943	Transposase
BZ15_3084	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BZ15_3086	COG2966	Psort location CytoplasmicMembrane, score
BZ15_3087	COG1280	lysine exporter protein (LysE YggA)
BZ15_3088	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BZ15_3089	COG0505	Belongs to the CarA family
BZ15_3091	COG1943	Transposase
BZ15_3093	COG1047	Peptidyl-prolyl cis-trans
BZ15_3096	COG0196	riboflavin kinase activity
BZ15_3098	COG0583	DNA-binding transcription factor activity
BZ15_31	COG2801	Transposase and inactivated derivatives
BZ15_3102	COG1584	GPR1 FUN34 yaaH family protein
BZ15_3105	COG0521	Mo-molybdopterin cofactor biosynthetic process
BZ15_3113	COG0745	RESPONSE REGULATOR receiver
BZ15_3114	COG3045	CreA protein
BZ15_3117	COG3708	Transcriptional regulator
BZ15_3117	COG2207	Transcriptional regulator
BZ15_3118	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BZ15_3120	COG0741	lytic transglycosylase activity
BZ15_3123	COG2199	diguanylate cyclase activity
BZ15_3124	COG2885	chlorophyll binding
BZ15_3125	COG0488	(ABC) transporter
BZ15_3126	COG0488	(ABC) transporter
BZ15_3130	COG0560	Phosphoserine phosphatase
BZ15_3131	COG3726	membrane protein affecting hemolysin expression
BZ15_3136	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ15_3137	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ15_3138	COG0084	hydrolase, TatD family'
BZ15_3139	COG4667	esterase of the alpha-beta hydrolase superfamily
BZ15_3141	COG2823	Periplasmic or secreted lipoprotein
BZ15_3143	COG0456	acetyltransferase
BZ15_3144	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BZ15_3148	COG3706	GGDEF domain
BZ15_315	COG2226	methyltransferase
BZ15_3151	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ15_3152	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ15_3155	COG0859	PFAM glycosyl transferase family 9
BZ15_3157	COG2390	Transcriptional regulator
BZ15_3158	COG2390	Transcriptional regulator
BZ15_3166	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_3166	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_3166	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ15_3167	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ15_3168	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ15_3169	COG2207	Transcriptional regulator
BZ15_3170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ15_3172	COG4269	membrane
BZ15_3182	COG2963	transposase activity
BZ15_3184	COG1401	restriction endodeoxyribonuclease activity
BZ15_3188	COG3650	response to hydrogen peroxide
BZ15_3189	COG1960	acyl-CoA dehydrogenase activity
BZ15_3190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ15_3191	COG0557	exoribonuclease II activity
BZ15_3194	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BZ15_3195	COG0330	HflC and HflK could
BZ15_3196	COG0330	HflC and HflK could
BZ15_3197	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BZ15_320	COG1940	carbohydrate kinase activity
BZ15_3201	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ15_3202	COG0802	atpase or kinase
BZ15_3203	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BZ15_3203	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZ15_3204	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BZ15_3207	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BZ15_3210	COG3264	Mechanosensitive ion channel
BZ15_3210	COG1511	domain protein
BZ15_3212	COG1053	succinate dehydrogenase
BZ15_3213	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZ15_3215	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BZ15_3216	COG1943	Transposase
BZ15_3217	COG2076	Multidrug Resistance protein
BZ15_3225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ15_3228	COG3383	formate dehydrogenase (NAD+) activity
BZ15_3229	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ15_323	COG0419	ATPase involved in DNA repair
BZ15_3230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ15_3230	COG0493	'glutamate synthase
BZ15_3231	COG1309	transcriptional regulator
BZ15_324	COG0420	3'-5' exonuclease activity
BZ15_3246	COG1454	alcohol dehydrogenase
BZ15_3248	COG0629	single-stranded DNA binding
BZ15_3249	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BZ15_325	COG0745	RESPONSE REGULATOR receiver
BZ15_3250	COG2315	Protein conserved in bacteria
BZ15_3251	COG1448	Aminotransferase
BZ15_3252	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZ15_3253	COG0305	Participates in initiation and elongation during chromosome replication
BZ15_3256	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ15_3257	COG0735	belongs to the Fur family
BZ15_3259	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BZ15_326	COG5002	protein histidine kinase activity
BZ15_3267	COG3121	Chaperone
BZ15_3279	COG1358	cellular component organization or biogenesis
BZ15_328	COG1114	Component of the transport system for branched-chain amino acids
BZ15_3284	COG3721	Heme iron utilization protein
BZ15_3285	COG0702	epimerase
BZ15_3286	COG4771	TonB-dependent receptor
BZ15_3287	COG3720	iron ion transport
BZ15_3288	COG4558	Periplasmic binding protein
BZ15_3289	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ15_3291	COG0626	cystathionine gamma-synthase activity
BZ15_3292	COG0814	amino acid
BZ15_3293	COG0583	DNA-binding transcription factor activity
BZ15_3294	COG0425	Belongs to the sulfur carrier protein TusA family
BZ15_3295	COG2391	methyltransferase activity
BZ15_330	COG0366	Alpha amylase catalytic
BZ15_3317	COG1301	dicarboxylic acid transport
BZ15_3319	COG3162	membrane
BZ15_3324	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BZ15_3327	COG0551	DNA topoisomerase type I activity
BZ15_3329	COG0758	DNA mediated transformation
BZ15_3333	COG0569	domain protein
BZ15_3335	COG3036	rescue of stalled ribosome
BZ15_3336	COG0789	Transcriptional regulator
BZ15_3339	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BZ15_334	COG1943	Transposase
BZ15_3342	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ15_3343	COG0201	protein transport
BZ15_3345	COG1841	ribosomal large subunit assembly
BZ15_335	COG0450	alkyl hydroperoxide reductase
BZ15_3353	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BZ15_3354	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BZ15_3356	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BZ15_3357	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BZ15_3359	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZ15_336	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BZ15_3364	COG0051	transcription antitermination factor activity, RNA binding
BZ15_3367	COG1943	Transposase
BZ15_337	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BZ15_3370	COG0049	tRNA binding
BZ15_3371	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BZ15_3375	COG2964	Protein conserved in bacteria
BZ15_3376	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ15_3378	COG1047	Peptidyl-prolyl cis-trans
BZ15_3379	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BZ15_3382	COG0488	(ABC) transporter
BZ15_3383	COG0488	(ABC) transporter
BZ15_3384	COG1216	Glycosyl transferase, family 2
BZ15_3386	COG2175	clavaminate synthase activity
BZ15_3387	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ15_3389	COG4521	taurine ABC transporter
BZ15_339	COG1862	Preprotein translocase
BZ15_3391	COG0429	hydrolase of the alpha beta-hydrolase fold
BZ15_3393	COG3954	Phosphoribulokinase
BZ15_3395	COG1765	OsmC-like protein
BZ15_3397	COG1289	transmembrane transporter activity
BZ15_34	COG0513	Belongs to the DEAD box helicase family
BZ15_340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ15_3400	COG0433	COG0433 Predicted ATPase
BZ15_3401	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ15_3402	COG1486	melibiose metabolic process
BZ15_3406	COG0402	S-adenosylhomocysteine deaminase activity
BZ15_3407	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BZ15_3408	COG2146	nitrite reductase [NAD(P)H] activity
BZ15_341	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ15_3411	COG0180	Tryptophanyl-tRNA synthetase
BZ15_3412	COG0546	phosphoglycolate phosphatase activity
BZ15_3413	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BZ15_3418	COG4796	Type ii and iii secretion system protein
BZ15_342	COG1943	Transposase
BZ15_3423	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BZ15_3424	COG0494	nUDIX hydrolase
BZ15_3427	COG1011	Hydrolase
BZ15_3428	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BZ15_3432	COG0745	RESPONSE REGULATOR receiver
BZ15_3433	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ15_3434	COG2183	response to ionizing radiation
BZ15_3435	COG1918	ferrous iron import across plasma membrane
BZ15_3442	COG1640	4-alpha-glucanotransferase
BZ15_3443	COG0058	SHG alpha-glucan phosphorylase activity
BZ15_3444	COG0058	SHG alpha-glucan phosphorylase activity
BZ15_3446	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZ15_3448	COG1349	DNA-binding transcription factor activity
BZ15_3450	COG2801	Transposase and inactivated derivatives
BZ15_3452	COG0460	homoserine dehydrogenase
BZ15_3452	COG0527	aspartate kinase activity
BZ15_3453	COG0626	cystathionine gamma-synthase activity
BZ15_3454	COG0626	cystathionine gamma-synthase activity
BZ15_3456	COG4682	membrane
BZ15_3458	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BZ15_346	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ15_346	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ15_3460	COG1609	Transcriptional regulator
BZ15_3461	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ15_3464	COG1575	Belongs to the MenA family. Type 1 subfamily
BZ15_3475	COG1943	Transposase
BZ15_3477	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZ15_3478	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ15_3479	COG1494	fructose-1,6-bisphosphatase
BZ15_3481	COG3152	Membrane
BZ15_3484	COG0583	DNA-binding transcription factor activity
BZ15_3485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BZ15_3486	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BZ15_3487	COG0471	metal ion transport
BZ15_3489	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BZ15_349	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BZ15_3494	COG3678	ATP-independent chaperone mediated protein folding
BZ15_3495	COG0745	RESPONSE REGULATOR receiver
BZ15_3496	COG2205	protein histidine kinase activity
BZ15_3497	COG2169	Transcriptional regulator
BZ15_3497	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ15_3498	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BZ15_3499	COG1045	serine acetyltransferase
BZ15_350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BZ15_3502	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ15_3503	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZ15_3505	COG4942	peptidase
BZ15_3506	COG2861	carbohydrate metabolic process
BZ15_3507	COG2861	carbohydrate metabolic process
BZ15_3509	COG0156	8-amino-7-oxononanoate synthase activity
BZ15_351	COG1943	Transposase
BZ15_3511	COG0859	PFAM glycosyl transferase family 9
BZ15_3512	COG0859	PFAM glycosyl transferase family 9
BZ15_3513	COG1519	Transferase
BZ15_3517	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BZ15_3520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZ15_3525	COG1561	YicC-like family, N-terminal region
BZ15_3526	COG2860	membrane
BZ15_3527	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BZ15_353	COG0142	geranyltranstransferase activity
BZ15_3530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ15_3531	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ15_3532	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZ15_3533	COG0786	glutamate:sodium symporter activity
BZ15_3534	COG2233	PERMEase
BZ15_3535	COG2982	Protein involved in outer membrane biogenesis
BZ15_3536	COG0456	acetyltransferase
BZ15_3540	COG1295	ribonuclease BN
BZ15_3541	COG1011	Hydrolase
BZ15_3543	COG0174	glutamine synthetase
BZ15_3544	COG3852	Histidine kinase
BZ15_3546	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ15_3549	COG1943	Transposase
BZ15_3550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ15_3550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ15_3551	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ15_3552	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BZ15_3553	COG3084	Protein conserved in bacteria
BZ15_3555	COG1763	Mo-molybdopterin cofactor biosynthetic process
BZ15_3556	COG3328	transposase activity
BZ15_356	COG0693	protein deglycase activity
BZ15_3561	COG2186	Transcriptional regulator
BZ15_3563	COG0477	Major facilitator Superfamily
BZ15_3564	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ15_357	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BZ15_3570	COG1522	sequence-specific DNA binding
BZ15_3571	COG0716	FMN binding
BZ15_3574	COG3312	ion transport
BZ15_3584	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BZ15_3585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BZ15_3586	COG0573	inorganic phosphate transmembrane transporter activity
BZ15_3587	COG0581	inorganic phosphate transmembrane transporter activity
BZ15_3589	COG0704	Plays a role in the regulation of phosphate uptake
BZ15_359	COG2814	Major facilitator Superfamily
BZ15_3591	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ15_3592	COG0765	amino acid transport
BZ15_3593	COG0765	amino acid transport
BZ15_3594	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ15_3595	COG2252	PERMEase
BZ15_3600	COG0706	membrane insertase activity
BZ15_3603	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BZ15_3606	COG0592	DNA-directed DNA polymerase activity
BZ15_3607	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BZ15_3608	COG0187	DNA topoisomerase II activity
BZ15_3609	COG0561	phosphatase activity
BZ15_361	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BZ15_3610	COG2801	Transposase and inactivated derivatives
BZ15_3613	COG2423	ornithine cyclodeaminase activity
BZ15_3614	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZ15_3615	COG0823	Involved in the tonB-independent uptake of proteins
BZ15_3616	COG0823	Involved in the tonB-independent uptake of proteins
BZ15_3617	COG5645	(Lipo)protein
BZ15_362	COG1845	cytochrome c oxidase, subunit III
BZ15_3621	COG3977	Valine--pyruvate aminotransferase
BZ15_3623	COG0366	Alpha amylase catalytic
BZ15_3626	COG2885	chlorophyll binding
BZ15_3628	COG2818	Glycosylase
BZ15_363	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BZ15_3633	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_3633	COG2213	PTS system mannitol-specific
BZ15_3635	COG3722	fumarate hydratase activity
BZ15_364	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BZ15_3642	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ15_3644	COG3383	formate dehydrogenase (NAD+) activity
BZ15_3644	COG0243	molybdopterin cofactor binding
BZ15_3645	COG3383	formate dehydrogenase (NAD+) activity
BZ15_3645	COG0243	molybdopterin cofactor binding
BZ15_3646	COG0437	4 iron, 4 sulfur cluster binding
BZ15_3647	COG2864	formate dehydrogenase
BZ15_3658	COG2801	Transposase and inactivated derivatives
BZ15_366	COG2223	nitrite transmembrane transporter activity
BZ15_3660	COG3274	enterobacterial common antigen metabolic process
BZ15_3662	COG3188	usher protein
BZ15_3663	COG3188	usher protein
BZ15_3664	COG3121	Chaperone
BZ15_3666	COG1070	Carbohydrate kinase
BZ15_3668	COG4213	ABC transporter substrate-binding protein
BZ15_367	COG3056	Lipoprotein
BZ15_3670	COG4214	carbohydrate transport
BZ15_3671	COG1609	Transcriptional regulator
BZ15_3671	COG2207	Transcriptional regulator
BZ15_3673	COG0582	viral genome integration into host DNA
BZ15_368	COG0271	Belongs to the BolA IbaG family
BZ15_3680	COG4604	ABC transporter, ATP-binding protein
BZ15_3682	COG4605	iron ion homeostasis
BZ15_3684	COG4607	ABC-type enterochelin transport system periplasmic component
BZ15_3687	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BZ15_3690	COG2986	histidine ammonia-lyase
BZ15_3693	COG2194	sulfuric ester hydrolase activity
BZ15_3694	COG2197	response regulator
BZ15_3695	COG3851	Histidine kinase
BZ15_3696	COG2271	Major facilitator Superfamily
BZ15_37	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ15_3700	COG2831	hemolysin activation secretion protein
BZ15_3702	COG0747	negative chemotaxis
BZ15_3703	COG0601	transmembrane transport
BZ15_3704	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ15_3705	COG0444	Belongs to the ABC transporter superfamily
BZ15_3706	COG4608	Belongs to the ABC transporter superfamily
BZ15_3707	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BZ15_3708	COG2200	EAL domain
BZ15_3708	COG2199	diguanylate cyclase activity
BZ15_3709	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ15_3714	COG0612	Peptidase, M16
BZ15_3715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ15_3716	COG1942	4-Oxalocrotonate Tautomerase
BZ15_3717	COG2200	EAL domain
BZ15_3718	COG2134	cdp-diacylglycerol pyrophosphatase
BZ15_3719	COG2982	Protein involved in outer membrane biogenesis
BZ15_3720	COG1295	ribonuclease BN
BZ15_3725	COG1929	Belongs to the glycerate kinase type-1 family
BZ15_3726	COG2610	gluconate transmembrane transporter activity
BZ15_3727	COG3835	regulator
BZ15_3728	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ15_3729	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BZ15_373	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZ15_3730	COG0339	signal peptide processing
BZ15_3734	COG0589	response to stress
BZ15_3736	COG1943	Transposase
BZ15_3737	COG0306	phosphate transporter
BZ15_3738	COG2081	HI0933 family
BZ15_374	COG0776	regulation of translation
BZ15_3741	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_3742	COG1879	ABC-type sugar transport system periplasmic component
BZ15_3744	COG0191	fructose-bisphosphate aldolase activity
BZ15_3746	COG0745	RESPONSE REGULATOR receiver
BZ15_3748	COG1741	Belongs to the pirin family
BZ15_3749	COG1609	Transcriptional regulator
BZ15_375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ15_3750	COG2610	gluconate transmembrane transporter activity
BZ15_3751	COG3265	gluconokinase activity
BZ15_3755	COG2095	MarC family integral membrane protein
BZ15_3756	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ15_376	COG1555	photosystem II stabilization
BZ15_3762	COG3275	phosphorelay sensor kinase activity
BZ15_3765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BZ15_3767	COG0058	SHG alpha-glucan phosphorylase activity
BZ15_3768	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ15_377	COG0824	Thioesterase
BZ15_3771	COG2801	Transposase and inactivated derivatives
BZ15_3779	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BZ15_3783	COG1629	transport
BZ15_3788	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ15_3789	COG0678	peroxiredoxin activity
BZ15_3789	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ15_379	COG4533	DNA binding
BZ15_3804	COG1879	ABC-type sugar transport system periplasmic component
BZ15_3805	COG1129	ABC transporter
BZ15_3806	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_3808	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_3809	COG3085	chromosome segregation
BZ15_3812	COG3978	acetolactate synthase activity
BZ15_3813	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ15_382	COG1522	sequence-specific DNA binding
BZ15_3822	COG0583	DNA-binding transcription factor activity
BZ15_3828	COG3121	Chaperone
BZ15_383	COG1132	(ABC) transporter
BZ15_3831	COG3121	Chaperone
BZ15_3833	COG3328	transposase activity
BZ15_3835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ15_384	COG1132	(ABC) transporter
BZ15_3840	COG3118	belongs to the thioredoxin family
BZ15_3841	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BZ15_3842	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BZ15_3843	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ15_3844	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BZ15_3845	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BZ15_3846	COG1088	dTDP-glucose 4,6-dehydratase activity
BZ15_3847	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BZ15_3848	COG0456	acetyltransferase
BZ15_3849	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BZ15_385	COG0347	Belongs to the P(II) protein family
BZ15_3850	COG2244	polysaccharide biosynthetic process
BZ15_3854	COG1113	amino acid transport
BZ15_386	COG0004	ammonium transporteR
BZ15_3860	COG1943	Transposase
BZ15_3861	COG3071	HemY protein
BZ15_3862	COG2959	enzyme of heme biosynthesis
BZ15_3863	COG1587	Uroporphyrinogen-III synthase
BZ15_3865	COG3072	Adenylate cyclase
BZ15_3867	COG5567	small periplasmic lipoprotein
BZ15_3869	COG3159	Protein conserved in bacteria
BZ15_387	COG1946	Acyl-CoA thioesterase
BZ15_3870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BZ15_3871	COG1011	Hydrolase
BZ15_3872	COG0210	DNA helicase
BZ15_3874	COG5441	Belongs to the UPF0261 family
BZ15_3877	COG5441	Belongs to the UPF0261 family
BZ15_3878	COG5564	TIM-barrel signal transduction protein
BZ15_3879	COG0598	Magnesium transport protein CorA
BZ15_388	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BZ15_3881	COG2050	protein possibly involved in aromatic compounds catabolism
BZ15_3882	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BZ15_3883	COG0514	ATP-dependent DNA helicase (RecQ)
BZ15_3884	COG1280	lysine exporter protein (LysE YggA)
BZ15_3885	COG1280	lysine exporter protein (LysE YggA)
BZ15_3886	COG2267	carboxylic ester hydrolase activity
BZ15_3887	COG0561	phosphatase activity
BZ15_3889	COG0584	glycerophosphoryl diester phosphodiesterase
BZ15_389	COG3695	enzyme binding
BZ15_3890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ15_3892	COG0247	lactate metabolic process
BZ15_3894	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BZ15_3897	COG3714	YhhN family
BZ15_3900	COG3776	membrane
BZ15_3901	COG0742	ribosomal rna small subunit methyltransferase
BZ15_3902	COG0552	protein localization to endoplasmic reticulum
BZ15_3902	COG0552	protein localization to endoplasmic reticulum
BZ15_3903	COG2884	Cell division ATP-binding protein ftsE
BZ15_3904	COG2177	Part of the ABC transporter FtsEX involved in
BZ15_3906	COG1943	Transposase
BZ15_3908	COG0683	leucine binding
BZ15_3909	COG0559	Belongs to the binding-protein-dependent transport system permease family
BZ15_3910	COG4177	L-phenylalanine transmembrane transporter activity
BZ15_3911	COG0411	ABC transporter
BZ15_3912	COG0410	ABC transporter
BZ15_3924	COG0584	glycerophosphoryl diester phosphodiesterase
BZ15_3925	COG0679	Auxin Efflux Carrier
BZ15_3926	COG0583	DNA-binding transcription factor activity
BZ15_3929	COG0412	Dienelactone hydrolase
BZ15_393	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ15_3930	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BZ15_3932	COG1966	Carbon starvation protein
BZ15_3933	COG0586	Pfam SNARE associated Golgi protein
BZ15_3934	COG1322	Protein conserved in bacteria
BZ15_3938	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ15_3940	COG0805	protein transport
BZ15_395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ15_3952	COG1739	Uncharacterized protein family UPF0029
BZ15_3953	COG1943	Transposase
BZ15_3954	COG1739	Uncharacterized protein family UPF0029
BZ15_3955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BZ15_3956	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BZ15_396	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ15_3962	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BZ15_397	COG1309	transcriptional regulator
BZ15_3973	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ15_3974	COG0250	Participates in transcription elongation, termination and antitermination
BZ15_398	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BZ15_3981	COG1943	Transposase
BZ15_3983	COG2022	thiamine diphosphate biosynthetic process
BZ15_3985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZ15_3987	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BZ15_399	COG1196	nuclear chromosome segregation
BZ15_399	COG3264	Mechanosensitive ion channel
BZ15_3992	COG1515	deoxyribonuclease V activity
BZ15_3993	COG3068	Protein conserved in bacteria
BZ15_3996	COG0151	Belongs to the GarS family
BZ15_40	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ15_4009	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BZ15_401	COG2832	Protein of unknown function (DUF454)
BZ15_4010	COG2224	Isocitrate lyase
BZ15_4012	COG1414	Transcriptional regulator
BZ15_4013	COG1414	Transcriptional regulator
BZ15_4017	COG0527	aspartate kinase activity
BZ15_4020	COG3833	ABC-type maltose transport systems, permease component
BZ15_4021	COG1175	transmembrane transport
BZ15_4032	COG2801	Transposase and inactivated derivatives
BZ15_4048	COG3501	Rhs element vgr protein
BZ15_405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BZ15_4051	COG3209	COG3209 Rhs family protein
BZ15_4057	COG3501	Rhs element vgr protein
BZ15_4059	COG3209	COG3209 Rhs family protein
BZ15_4062	COG0673	inositol 2-dehydrogenase activity
BZ15_4063	COG1917	Cupin 2, conserved barrel domain protein
BZ15_4063	COG2207	Transcriptional regulator
BZ15_4064	COG1869	D-ribose catabolic process
BZ15_4065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ15_4067	COG0431	NADPH-dependent FMN reductase
BZ15_4068	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ15_4070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ15_4072	COG3077	Addiction module antitoxin, RelB DinJ family
BZ15_4073	COG2252	PERMEase
BZ15_4074	COG0025	NhaP-type Na H and K H
BZ15_4076	COG1560	Kdo2-lipid A biosynthetic process
BZ15_4078	COG1129	ABC transporter
BZ15_4079	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_4081	COG1069	ribulokinase activity
BZ15_4083	COG0625	glutathione transferase activity
BZ15_4086	COG1943	Transposase
BZ15_4087	COG1278	Cold shock
BZ15_4088	COG1278	Cold shock
BZ15_4089	COG3133	Outer membrane lipoprotein
BZ15_4090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ15_4092	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ15_4096	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BZ15_4097	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ15_4099	COG4145	pantothenate transmembrane transporter activity
BZ15_4100	COG3924	membrane
BZ15_4102	COG0439	Biotin carboxylase
BZ15_4103	COG0511	ligase activity, forming carbon-carbon bonds
BZ15_4106	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BZ15_4107	COG0604	alcohol dehydrogenase
BZ15_4108	COG2200	EAL domain
BZ15_4108	COG2199	diguanylate cyclase activity
BZ15_4109	COG1077	Cell shape determining protein MreB Mrl
BZ15_411	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ15_411	COG0543	2 iron, 2 sulfur cluster binding
BZ15_4110	COG1792	Involved in formation and maintenance of cell shape
BZ15_4111	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BZ15_4113	COG1530	ribonuclease E activity
BZ15_4114	COG3164	Protein of unknown function
BZ15_4115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ15_4116	COG0312	modulator of DNA gyrase
BZ15_4127	COG0583	DNA-binding transcription factor activity
BZ15_4131	COG1012	belongs to the aldehyde dehydrogenase family
BZ15_4134	COG2732	(Barnase) inhibitor
BZ15_4136	COG0312	modulator of DNA gyrase
BZ15_4138	COG3783	Cytochrome b(562)
BZ15_4139	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ15_4140	COG0366	Alpha amylase catalytic
BZ15_4141	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ15_4141	COG1263	PTS System
BZ15_4142	COG1609	Transcriptional regulator
BZ15_4149	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ15_4151	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_4153	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BZ15_4154	COG1137	ATPase activity
BZ15_4155	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BZ15_4156	COG3117	lipopolysaccharide transmembrane transporter activity
BZ15_4157	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BZ15_4158	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZ15_4158	COG0517	IMP dehydrogenase activity
BZ15_4159	COG0530	calcium, potassium:sodium antiporter activity
BZ15_4160	COG1127	ABC transporter
BZ15_4161	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BZ15_4162	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ15_4163	COG2854	intermembrane phospholipid transfer
BZ15_4164	COG3113	response to antibiotic
BZ15_4165	COG5007	Belongs to the BolA IbaG family
BZ15_4167	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ15_4168	COG1943	Transposase
BZ15_4169	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ15_4170	COG3105	Protein conserved in bacteria
BZ15_4171	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BZ15_4174	COG0625	glutathione transferase activity
BZ15_4175	COG2969	positive regulation of protein catabolic process
BZ15_4177	COG0493	'glutamate synthase
BZ15_4178	COG0067	glutamate synthase
BZ15_4178	COG0069	glutamate synthase activity
BZ15_4178	COG0070	glutamate synthase
BZ15_4179	COG1242	4 iron, 4 sulfur cluster binding
BZ15_4180	COG5002	protein histidine kinase activity
BZ15_4180	COG2198	Histidine kinase
BZ15_4180	COG0784	Response regulator, receiver
BZ15_4181	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BZ15_4183	COG2823	Periplasmic or secreted lipoprotein
BZ15_4187	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BZ15_4188	COG1741	Belongs to the pirin family
BZ15_4189	COG0583	DNA-binding transcription factor activity
BZ15_4190	COG0435	Glutathione S-transferase
BZ15_4194	COG1073	alpha beta
BZ15_4196	COG0360	Binds together with S18 to 16S ribosomal RNA
BZ15_4197	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZ15_4199	COG1943	Transposase
BZ15_4201	COG3061	Opacity-associated protein A
BZ15_4202	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ15_4204	COG0737	Belongs to the 5'-nucleotidase family
BZ15_4206	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BZ15_4208	COG1253	flavin adenine dinucleotide binding
BZ15_4210	COG0729	surface antigen
BZ15_4211	COG2911	Protein conserved in bacteria
BZ15_4212	COG2105	PFAM AIG2 family protein
BZ15_4213	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BZ15_4222	COG1475	DNA binding
BZ15_4223	COG1475	DNA binding
BZ15_4224	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZ15_4233	COG1943	Transposase
BZ15_4239	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ15_424	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BZ15_425	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BZ15_4250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BZ15_4252	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ15_4271	COG3328	transposase activity
BZ15_4273	COG3344	reverse transcriptase
BZ15_4275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZ15_4291	COG1475	DNA binding
BZ15_4294	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BZ15_4296	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZ15_4296	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZ15_4303	COG3941	tape measure
BZ15_431	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ15_432	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ15_4321	COG4669	(LipO)protein
BZ15_4323	COG1317	bacterial-type flagellum organization
BZ15_4324	COG5599	Phosphatase
BZ15_4325	COG2963	transposase activity
BZ15_4326	COG2801	Transposase and inactivated derivatives
BZ15_433	COG4651	solute:proton antiporter activity
BZ15_433	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ15_4330	COG2801	Transposase and inactivated derivatives
BZ15_4332	COG0515	serine threonine protein kinase
BZ15_434	COG2223	nitrite transmembrane transporter activity
BZ15_435	COG0737	Belongs to the 5'-nucleotidase family
BZ15_4350	COG2801	Transposase and inactivated derivatives
BZ15_4355	COG2801	Transposase and inactivated derivatives
BZ15_436	COG0737	Belongs to the 5'-nucleotidase family
BZ15_4363	COG2801	Transposase and inactivated derivatives
BZ15_4365	COG5599	Phosphatase
BZ15_4367	COG3609	addiction module antidote protein, CC2985 family
BZ15_4369	COG1475	DNA binding
BZ15_437	COG0737	Belongs to the 5'-nucleotidase family
BZ15_4370	COG1192	Involved in chromosome partitioning
BZ15_4372	COG2801	Transposase and inactivated derivatives
BZ15_4376	COG3177	Filamentation induced by cAMP protein fic
BZ15_4381	COG4886	Leucine-rich repeat (LRR) protein
BZ15_4385	COG0457	Tetratricopeptide repeat
BZ15_4389	COG4789	Type iii secretion
BZ15_4398	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZ15_4399	COG4790	Type iii secretion
BZ15_440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BZ15_4400	COG4794	Type iii secretion
BZ15_4401	COG4791	protein targeting
BZ15_4402	COG4792	protein secretion
BZ15_4404	COG2207	Transcriptional regulator
BZ15_441	COG3735	TraB family
BZ15_4411	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BZ15_442	COG2217	Heavy metal translocating P-type atpase
BZ15_443	COG0789	Transcriptional regulator
BZ15_444	COG1585	Membrane protein implicated in regulation of membrane protease activity
BZ15_445	COG0330	HflC and HflK could
BZ15_446	COG3118	belongs to the thioredoxin family
BZ15_447	COG0300	oxidoreductase activity
BZ15_448	COG2755	lipolytic protein G-D-S-L family
BZ15_449	COG4181	ATPase activity
BZ15_45	COG3153	acetyltransferase
BZ15_450	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BZ15_451	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BZ15_452	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZ15_454	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ15_457	COG1943	Transposase
BZ15_459	COG1393	Belongs to the ArsC family
BZ15_460	COG4783	chaperone-mediated protein folding
BZ15_461	COG0628	permease
BZ15_464	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZ15_465	COG2716	regulation of RNA biosynthetic process
BZ15_467	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BZ15_468	COG1943	Transposase
BZ15_470	COG2321	neutral zinc metallopeptidase
BZ15_474	COG1876	peptidase activity
BZ15_476	COG1393	Belongs to the ArsC family
BZ15_478	COG1840	ABC-type Fe3 transport system, periplasmic component
BZ15_479	COG1175	transmembrane transport
BZ15_480	COG3842	ATPase activity
BZ15_481	COG3119	arylsulfatase activity
BZ15_482	COG0641	radical SAM
BZ15_483	COG1988	membrane-bound metal-dependent
BZ15_485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ15_487	COG2197	response regulator
BZ15_488	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ15_488	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ15_489	COG3062	negative regulation of establishment of protein localization
BZ15_49	COG1653	transport
BZ15_491	COG3043	anaerobic respiration
BZ15_492	COG3005	denitrification pathway
BZ15_5	COG3423	Transcriptional regulator
BZ15_501	COG3111	PFAM Bacterial OB fold (BOF) protein
BZ15_503	COG2837	iron assimilation
BZ15_504	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BZ15_506	COG4886	Leucine-rich repeat (LRR) protein
BZ15_508	COG2731	YhcH YjgK YiaL family protein
BZ15_509	COG1737	Transcriptional regulator
BZ15_51	COG0395	ABC-type sugar transport system, permease component
BZ15_511	COG4150	thiosulfate binding
BZ15_512	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BZ15_513	COG4208	sulfate ABC transporter
BZ15_514	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BZ15_517	COG0745	RESPONSE REGULATOR receiver
BZ15_518	COG5002	protein histidine kinase activity
BZ15_518	COG3850	Histidine kinase
BZ15_52	COG3842	ATPase activity
BZ15_520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZ15_522	COG0006	proline dipeptidase activity
BZ15_524	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BZ15_527	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ15_528	COG0745	RESPONSE REGULATOR receiver
BZ15_529	COG2205	protein histidine kinase activity
BZ15_531	COG1943	Transposase
BZ15_532	COG2190	(PTS) system
BZ15_534	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ15_535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZ15_536	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BZ15_539	COG3530	Putative quorum-sensing-regulated virulence factor
BZ15_545	COG1943	Transposase
BZ15_55	COG0702	epimerase
BZ15_550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ15_553	COG0667	Aldo Keto reductase
BZ15_558	COG0436	Aminotransferase
BZ15_559	COG3038	cytochrome b561
BZ15_56	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BZ15_565	COG3381	protein complex oligomerization
BZ15_566	COG3302	dmso reductase anchor subunit
BZ15_567	COG0437	4 iron, 4 sulfur cluster binding
BZ15_568	COG0243	molybdopterin cofactor binding
BZ15_57	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BZ15_575	COG2951	lytic endotransglycosylase activity
BZ15_58	COG3454	Phosphonate metabolism
BZ15_587	COG3121	Chaperone
BZ15_588	COG3188	usher protein
BZ15_589	COG3328	transposase activity
BZ15_59	COG4778	phosphonate C-P lyase system protein PhnL
BZ15_590	COG3188	usher protein
BZ15_60	COG4107	phosphonate C-P lyase system protein PhnK
BZ15_601	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BZ15_603	COG1943	Transposase
BZ15_604	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ15_605	COG1737	Transcriptional regulator
BZ15_607	COG0560	Phosphoserine phosphatase
BZ15_608	COG0590	tRNA wobble adenosine to inosine editing
BZ15_61	COG3627	carbon phosphorus lyase activity
BZ15_614	COG1943	Transposase
BZ15_615	COG2205	protein histidine kinase activity
BZ15_616	COG3170	Tfp pilus assembly protein FimV
BZ15_617	COG2204	response regulator
BZ15_618	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BZ15_618	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ15_619	COG0347	Belongs to the P(II) protein family
BZ15_62	COG3626	phosphonate metabolism
BZ15_622	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ15_622	COG1017	nitric oxide dioxygenase activity
BZ15_625	COG3711	transcriptional antiterminator
BZ15_626	COG2814	Major facilitator Superfamily
BZ15_627	COG3683	transport system, periplasmic component
BZ15_628	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ15_629	COG1943	Transposase
BZ15_63	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BZ15_630	COG0483	inositol monophosphate 1-phosphatase activity
BZ15_633	COG1104	cysteine desulfurase activity
BZ15_634	COG0822	iron-sulfur transferase activity
BZ15_637	COG0443	Heat shock 70 kDa protein
BZ15_638	COG0633	Ferredoxin
BZ15_639	COG2975	iron-sulfur cluster assembly
BZ15_64	COG3624	Phosphonate C-P lyase system protein PhnG
BZ15_643	COG3468	outer membrane autotransporter barrel domain protein
BZ15_644	COG3468	outer membrane autotransporter barrel domain protein
BZ15_65	COG2188	Transcriptional regulator
BZ15_652	COG2976	Protein conserved in bacteria
BZ15_653	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ15_656	COG1645	bacterial-type flagellum-dependent swarming motility
BZ15_658	COG0517	IMP dehydrogenase activity
BZ15_658	COG0516	GMP reductase activity
BZ15_660	COG1943	Transposase
BZ15_668	COG3328	transposase activity
BZ15_671	COG0351	phosphomethylpyrimidine kinase
BZ15_677	COG3422	double-strand break repair
BZ15_678	COG0745	RESPONSE REGULATOR receiver
BZ15_679	COG2205	protein histidine kinase activity
BZ15_684	COG3842	ATPase activity
BZ15_686	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZ15_688	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ15_689	COG1177	transmembrane transport
BZ15_69	COG4608	Belongs to the ABC transporter superfamily
BZ15_690	COG0443	Heat shock 70 kDa protein
BZ15_691	COG2239	Acts as a magnesium transporter
BZ15_692	COG0248	Ppx GppA phosphatase
BZ15_693	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BZ15_695	COG0581	inorganic phosphate transmembrane transporter activity
BZ15_699	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ15_7	COG0142	geranyltranstransferase activity
BZ15_70	COG0444	Belongs to the ABC transporter superfamily
BZ15_700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BZ15_703	COG1943	Transposase
BZ15_704	COG2501	S4 domain
BZ15_71	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ15_712	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZ15_713	COG4589	Belongs to the CDS family
BZ15_715	COG2267	carboxylic ester hydrolase activity
BZ15_716	COG2453	phosphatase
BZ15_716	COG0671	phosphoesterase, PA-phosphatase related
BZ15_72	COG0601	transmembrane transport
BZ15_722	COG0667	Aldo Keto reductase
BZ15_723	COG0656	L-ascorbic acid biosynthetic process
BZ15_728	COG3328	transposase activity
BZ15_729	COG2850	peptidyl-arginine hydroxylation
BZ15_739	COG3423	Transcriptional regulator
BZ15_740	COG4953	penicillin-binding protein 1C
BZ15_741	COG3328	transposase activity
BZ15_743	COG3037	sugar-specific permease SgaT UlaA
BZ15_744	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BZ15_745	COG0622	Phosphoesterase
BZ15_747	COG1090	epimerase
BZ15_748	COG4598	ABC transporter
BZ15_749	COG4160	amino acid transport
BZ15_75	COG2731	YhcH YjgK YiaL family protein
BZ15_750	COG4215	(ABC) transporter
BZ15_751	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ15_752	COG0163	prenyltransferase activity
BZ15_753	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BZ15_754	COG1286	toxin biosynthetic process
BZ15_755	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BZ15_756	COG0285	dihydrofolate synthase activity
BZ15_758	COG0586	Pfam SNARE associated Golgi protein
BZ15_76	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BZ15_760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ15_761	COG1943	Transposase
BZ15_764	COG0697	spore germination
BZ15_767	COG1794	racemase activity, acting on amino acids and derivatives
BZ15_768	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ15_77	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BZ15_771	COG3101	peptidyl-lysine hydroxylation
BZ15_772	COG0730	response to heat
BZ15_773	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BZ15_775	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ15_777	COG2062	phosphohistidine phosphatase, SixA
BZ15_780	COG3691	Protein conserved in bacteria
BZ15_783	COG3088	subunit of a heme lyase
BZ15_783	COG4235	cytochrome complex assembly
BZ15_784	COG3088	subunit of a heme lyase
BZ15_784	COG4235	cytochrome complex assembly
BZ15_785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZ15_786	COG1138	Cytochrome C-type biogenesis protein
BZ15_788	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ15_789	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ15_79	COG0525	valine-tRNA ligase activity
BZ15_790	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ15_794	COG1704	LemA family
BZ15_796	COG2824	Alkylphosphonate utilization operon protein PhnA
BZ15_80	COG2927	DNA polymerase III (CHI subunit)
BZ15_802	COG3501	Rhs element vgr protein
BZ15_810	COG0681	Belongs to the peptidase S26 family
BZ15_813	COG3086	response to oxidative stress
BZ15_816	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BZ15_818	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BZ15_82	COG0795	lipopolysaccharide-transporting ATPase activity
BZ15_820	COG0513	Belongs to the DEAD box helicase family
BZ15_83	COG0795	lipopolysaccharide-transporting ATPase activity
BZ15_831	COG1984	allophanate hydrolase subunit 2
BZ15_832	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BZ15_834	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BZ15_835	COG5212	phosphodiesterase
BZ15_837	COG3272	Protein of unknown function (DUF1722)
BZ15_842	COG2205	protein histidine kinase activity
BZ15_843	COG0745	RESPONSE REGULATOR receiver
BZ15_847	COG0033	Phosphoglucomutase
BZ15_848	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BZ15_85	COG0582	viral genome integration into host DNA
BZ15_852	COG2169	Transcriptional regulator
BZ15_852	COG1917	Cupin 2, conserved barrel domain protein
BZ15_853	COG1447	Phosphotransferase system cellobiose-specific component IIA
BZ15_854	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ15_855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ15_856	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ15_857	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ15_858	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ15_860	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ15_861	COG4413	Urea transporter
BZ15_863	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BZ15_870	COG1124	(ABC) transporter
BZ15_871	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BZ15_872	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ15_874	COG0747	negative chemotaxis
BZ15_875	COG1278	Cold shock
BZ15_877	COG3328	transposase activity
BZ15_885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZ15_886	COG4175	Glycine betaine
BZ15_887	COG4176	ABC-type proline glycine betaine transport system permease component
BZ15_888	COG2113	Glycine betaine
BZ15_892	COG0582	viral genome integration into host DNA
BZ15_893	COG2963	transposase activity
BZ15_895	COG0596	Alpha beta hydrolase
BZ15_899	COG0735	belongs to the Fur family
BZ15_90	COG1943	Transposase
BZ15_904	COG1943	Transposase
BZ15_905	COG1263	PTS System
BZ15_905	COG2190	(PTS) system
BZ15_905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ15_907	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BZ15_908	COG1846	Transcriptional regulator
BZ15_908	COG1940	carbohydrate kinase activity
BZ15_909	COG0647	UMP catabolic process
BZ15_910	COG0367	asparagine synthase
BZ15_916	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ15_918	COG1702	phosphate starvation-inducible protein PhoH
BZ15_920	COG4535	Mg2 and Co2 transporter CorC
BZ15_921	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BZ15_923	COG0765	amino acid transport
BZ15_924	COG0765	amino acid transport
BZ15_925	COG1126	abc transporter atp-binding protein
BZ15_926	COG2888	peptidyl-tyrosine sulfation
BZ15_929	COG1466	dna polymerase III delta subunit
BZ15_93	COG0237	dephospho-CoA kinase activity
BZ15_931	COG0799	negative regulation of ribosome biogenesis
BZ15_933	COG0768	penicillin binding
BZ15_934	COG0772	Belongs to the SEDS family
BZ15_935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ15_936	COG1686	Belongs to the peptidase S11 family
BZ15_940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ15_941	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ15_942	COG1278	Cold shock
BZ15_944	COG2197	response regulator
BZ15_949	COG5265	(ABC) transporter
BZ15_95	COG1459	type II secretion system
BZ15_951	COG3718	enzyme involved in inositol metabolism
BZ15_953	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ15_954	COG0673	inositol 2-dehydrogenase activity
BZ15_955	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ15_956	COG1129	ABC transporter
BZ15_957	COG1879	ABC-type sugar transport system periplasmic component
BZ15_958	COG0673	inositol 2-dehydrogenase activity
BZ15_959	COG0673	inositol 2-dehydrogenase activity
BZ15_96	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZ15_960	COG3962	Belongs to the TPP enzyme family
BZ15_966	COG2373	Large extracellular alpha-helical protein
BZ15_967	COG4953	penicillin-binding protein 1C
BZ15_968	COG3328	transposase activity
BZ15_97	COG4969	Belongs to the N-Me-Phe pilin family
BZ15_971	COG1609	Transcriptional regulator
BZ15_972	COG0857	belongs to the CobB CobQ family
BZ15_972	COG0280	phosphate acetyltransferase
BZ15_976	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ15_977	COG0471	metal ion transport
BZ15_977	COG0490	domain, Protein
BZ15_979	COG0436	Aminotransferase
BZ15_980	COG0583	DNA-binding transcription factor activity
BZ15_982	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ15_984	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BZ15_986	COG1034	ATP synthesis coupled electron transport
BZ15_989	COG0839	Belongs to the complex I subunit 6 family
BZ15_99	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ15_991	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BZ15_992	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ15_995	COG2731	YhcH YjgK YiaL family protein
BZ15_996	COG3265	gluconokinase activity
BZ15_997	COG1028	Short-chain dehydrogenase reductase Sdr
BZ15_999	COG1609	Transcriptional regulator