locus-tag	class	description
YPZ3_0001	COG0716	FMN binding
YPZ3_0002	COG1522	sequence-specific DNA binding
YPZ3_0008	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_0009	COG0477	Major facilitator Superfamily
YPZ3_0010	COG2186	Transcriptional regulator
YPZ3_0011	COG3328	transposase activity
YPZ3_0012	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPZ3_0014	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPZ3_0015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPZ3_0016	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPZ3_0016	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPZ3_0017	COG1943	Transposase
YPZ3_0020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPZ3_0022	COG3852	Histidine kinase
YPZ3_0023	COG0174	glutamine synthetase
YPZ3_0025	COG1011	Hydrolase
YPZ3_0026	COG1295	ribonuclease BN
YPZ3_0030	COG0456	acetyltransferase
YPZ3_0031	COG2982	Protein involved in outer membrane biogenesis
YPZ3_0032	COG2233	PERMEase
YPZ3_0033	COG0786	glutamate:sodium symporter activity
YPZ3_0034	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPZ3_0035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPZ3_0036	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPZ3_0038	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YPZ3_0039	COG2860	membrane
YPZ3_0040	COG1561	YicC-like family, N-terminal region
YPZ3_0045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPZ3_0050	COG1519	Transferase
YPZ3_0051	COG0859	PFAM glycosyl transferase family 9
YPZ3_0052	COG0859	PFAM glycosyl transferase family 9
YPZ3_0054	COG0156	8-amino-7-oxononanoate synthase activity
YPZ3_0056	COG2861	carbohydrate metabolic process
YPZ3_0057	COG2861	carbohydrate metabolic process
YPZ3_0058	COG4942	peptidase
YPZ3_0060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPZ3_0063	COG1045	serine acetyltransferase
YPZ3_0064	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPZ3_0065	COG2169	Transcriptional regulator
YPZ3_0065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPZ3_0066	COG2205	protein histidine kinase activity
YPZ3_0067	COG0745	RESPONSE REGULATOR receiver
YPZ3_0068	COG3678	ATP-independent chaperone mediated protein folding
YPZ3_0072	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPZ3_0074	COG0471	metal ion transport
YPZ3_0075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPZ3_0076	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPZ3_0077	COG0583	DNA-binding transcription factor activity
YPZ3_0080	COG3152	Membrane
YPZ3_0082	COG1494	fructose-1,6-bisphosphatase
YPZ3_0083	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPZ3_0084	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPZ3_0090	COG1575	Belongs to the MenA family. Type 1 subfamily
YPZ3_0093	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPZ3_0094	COG1609	Transcriptional regulator
YPZ3_0095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPZ3_0096	COG4682	membrane
YPZ3_0098	COG0626	cystathionine gamma-synthase activity
YPZ3_0099	COG0527	aspartate kinase activity
YPZ3_0099	COG0460	homoserine dehydrogenase
YPZ3_0101	COG2801	Transposase and inactivated derivatives
YPZ3_0103	COG1349	DNA-binding transcription factor activity
YPZ3_0105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPZ3_0107	COG0058	SHG alpha-glucan phosphorylase activity
YPZ3_0108	COG0058	SHG alpha-glucan phosphorylase activity
YPZ3_0109	COG1640	4-alpha-glucanotransferase
YPZ3_0114	COG2183	response to ionizing radiation
YPZ3_0115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPZ3_0116	COG0745	RESPONSE REGULATOR receiver
YPZ3_0120	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPZ3_0121	COG1011	Hydrolase
YPZ3_0123	COG0494	nUDIX hydrolase
YPZ3_0124	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPZ3_0129	COG4796	Type ii and iii secretion system protein
YPZ3_0134	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPZ3_0135	COG0546	phosphoglycolate phosphatase activity
YPZ3_0136	COG0180	Tryptophanyl-tRNA synthetase
YPZ3_0139	COG2146	nitrite reductase [NAD(P)H] activity
YPZ3_0140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPZ3_0141	COG0402	S-adenosylhomocysteine deaminase activity
YPZ3_0145	COG1486	melibiose metabolic process
YPZ3_0146	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPZ3_0147	COG0433	COG0433 Predicted ATPase
YPZ3_0150	COG1289	transmembrane transporter activity
YPZ3_0152	COG1765	OsmC-like protein
YPZ3_0154	COG3954	Phosphoribulokinase
YPZ3_0155	COG0429	hydrolase of the alpha beta-hydrolase fold
YPZ3_0157	COG4521	taurine ABC transporter
YPZ3_0159	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPZ3_0160	COG2175	clavaminate synthase activity
YPZ3_0162	COG1216	Glycosyl transferase, family 2
YPZ3_0163	COG0488	(ABC) transporter
YPZ3_0164	COG0488	(ABC) transporter
YPZ3_0165	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPZ3_0167	COG1047	Peptidyl-prolyl cis-trans
YPZ3_0168	COG0545	Peptidyl-prolyl cis-trans isomerase
YPZ3_0169	COG2964	Protein conserved in bacteria
YPZ3_0172	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPZ3_0173	COG0049	tRNA binding
YPZ3_0176	COG1943	Transposase
YPZ3_0178	COG0051	transcription antitermination factor activity, RNA binding
YPZ3_0184	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPZ3_0185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPZ3_0186	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPZ3_0195	COG0201	protein transport
YPZ3_0198	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPZ3_0201	COG0789	Transcriptional regulator
YPZ3_0203	COG0569	domain protein
YPZ3_0207	COG0758	DNA mediated transformation
YPZ3_0209	COG0551	DNA topoisomerase type I activity
YPZ3_0212	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPZ3_0217	COG3162	membrane
YPZ3_0219	COG1301	dicarboxylic acid transport
YPZ3_0236	COG2391	methyltransferase activity
YPZ3_0237	COG0583	DNA-binding transcription factor activity
YPZ3_0238	COG0814	amino acid
YPZ3_0239	COG0626	cystathionine gamma-synthase activity
YPZ3_0241	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_0242	COG4558	Periplasmic binding protein
YPZ3_0243	COG3720	iron ion transport
YPZ3_0244	COG4771	TonB-dependent receptor
YPZ3_0245	COG0702	epimerase
YPZ3_0246	COG3721	Heme iron utilization protein
YPZ3_0251	COG1358	cellular component organization or biogenesis
YPZ3_0263	COG3121	Chaperone
YPZ3_0270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPZ3_0272	COG0735	belongs to the Fur family
YPZ3_0273	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPZ3_0275	COG0305	Participates in initiation and elongation during chromosome replication
YPZ3_0276	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPZ3_0277	COG1448	Aminotransferase
YPZ3_0278	COG2315	Protein conserved in bacteria
YPZ3_0279	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPZ3_0280	COG0629	single-stranded DNA binding
YPZ3_0282	COG1454	alcohol dehydrogenase
YPZ3_0292	COG0305	Participates in initiation and elongation during chromosome replication
YPZ3_0299	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPZ3_0336	COG3436	PFAM IS66 Orf2 family protein
YPZ3_0337	COG4372	Transposase
YPZ3_0338	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_0343	COG1309	transcriptional regulator
YPZ3_0344	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_0344	COG0493	'glutamate synthase
YPZ3_0345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_0346	COG3383	formate dehydrogenase (NAD+) activity
YPZ3_0349	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPZ3_0356	COG2076	Multidrug Resistance protein
YPZ3_0357	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPZ3_0359	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPZ3_0360	COG1053	succinate dehydrogenase
YPZ3_0362	COG1511	domain protein
YPZ3_0362	COG3264	Mechanosensitive ion channel
YPZ3_0365	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YPZ3_0366	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPZ3_0367	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPZ3_0367	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPZ3_0368	COG0802	atpase or kinase
YPZ3_0369	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPZ3_0373	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPZ3_0374	COG0330	HflC and HflK could
YPZ3_0375	COG0330	HflC and HflK could
YPZ3_0378	COG0557	exoribonuclease II activity
YPZ3_0379	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPZ3_0380	COG1960	acyl-CoA dehydrogenase activity
YPZ3_0381	COG3650	response to hydrogen peroxide
YPZ3_0384	COG1401	restriction endodeoxyribonuclease activity
YPZ3_0392	COG4269	membrane
YPZ3_0394	COG2207	Transcriptional regulator
YPZ3_0395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_0396	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_0397	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_0398	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPZ3_0398	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_0398	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_0406	COG2390	Transcriptional regulator
YPZ3_0408	COG0859	PFAM glycosyl transferase family 9
YPZ3_0410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_0411	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_0413	COG3706	GGDEF domain
YPZ3_0416	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPZ3_0417	COG0456	acetyltransferase
YPZ3_0419	COG2823	Periplasmic or secreted lipoprotein
YPZ3_0420	COG4667	esterase of the alpha-beta hydrolase superfamily
YPZ3_0421	COG0084	hydrolase, TatD family'
YPZ3_0422	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPZ3_0423	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPZ3_0428	COG3726	membrane protein affecting hemolysin expression
YPZ3_0429	COG0560	Phosphoserine phosphatase
YPZ3_0433	COG0488	(ABC) transporter
YPZ3_0434	COG0488	(ABC) transporter
YPZ3_0435	COG2885	chlorophyll binding
YPZ3_0436	COG2199	diguanylate cyclase activity
YPZ3_0439	COG0741	lytic transglycosylase activity
YPZ3_0440	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPZ3_0443	COG2207	Transcriptional regulator
YPZ3_0443	COG3708	Transcriptional regulator
YPZ3_0444	COG3045	CreA protein
YPZ3_0445	COG0745	RESPONSE REGULATOR receiver
YPZ3_0451	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPZ3_0454	COG1584	GPR1 FUN34 yaaH family protein
YPZ3_0458	COG0583	DNA-binding transcription factor activity
YPZ3_0459	COG0196	riboflavin kinase activity
YPZ3_0460	COG0196	riboflavin kinase activity
YPZ3_0463	COG1047	Peptidyl-prolyl cis-trans
YPZ3_0465	COG1943	Transposase
YPZ3_0467	COG0505	Belongs to the CarA family
YPZ3_0468	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPZ3_0469	COG1280	lysine exporter protein (LysE YggA)
YPZ3_0470	COG2966	Psort location CytoplasmicMembrane, score
YPZ3_0472	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPZ3_0478	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YPZ3_0479	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPZ3_0481	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPZ3_0482	COG0564	pseudouridine synthase activity
YPZ3_0492	COG3501	Rhs element vgr protein
YPZ3_0499	COG3047	cAMP biosynthetic process
YPZ3_0499	COG2885	chlorophyll binding
YPZ3_0503	COG0417	DNA replication proofreading
YPZ3_0504	COG0586	Pfam SNARE associated Golgi protein
YPZ3_0506	COG1178	ABC-type Fe3 transport system permease component
YPZ3_0507	COG4143	(ABC) transporter
YPZ3_0509	COG2814	Major facilitator Superfamily
YPZ3_0514	COG0473	3-isopropylmalate dehydrogenase activity
YPZ3_0516	COG1943	Transposase
YPZ3_0518	COG1022	Amp-dependent synthetase and ligase
YPZ3_0519	COG0028	Belongs to the TPP enzyme family
YPZ3_0522	COG1609	Transcriptional regulator
YPZ3_0526	COG3116	cell division
YPZ3_0527	COG0768	penicillin binding
YPZ3_0528	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPZ3_0529	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPZ3_0532	COG0772	Belongs to the SEDS family
YPZ3_0536	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPZ3_0537	COG0849	cell division
YPZ3_0538	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPZ3_0543	COG0494	nUDIX hydrolase
YPZ3_0546	COG2259	Doxx family
YPZ3_0547	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPZ3_0548	COG4575	ribosome binding
YPZ3_0551	COG0586	Pfam SNARE associated Golgi protein
YPZ3_0554	COG2271	Major facilitator Superfamily
YPZ3_0556	COG0246	Mannitol dehydrogenase
YPZ3_0557	COG2721	sulfolactate sulfo-lyase activity
YPZ3_0561	COG0673	inositol 2-dehydrogenase activity
YPZ3_0562	COG1451	nucleotide metabolic process
YPZ3_0565	COG1902	pentaerythritol trinitrate reductase activity
YPZ3_0565	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPZ3_0566	COG3247	response to pH
YPZ3_0569	COG4245	von Willebrand factor, type A
YPZ3_0572	COG4245	von Willebrand factor, type A
YPZ3_0573	COG2831	hemolysin activation secretion protein
YPZ3_0574	COG3210	domain, Protein
YPZ3_0575	COG3210	domain, Protein
YPZ3_0580	COG3842	ATPase activity
YPZ3_0581	COG3459	Glycosyltransferase 36 associated
YPZ3_0582	COG1609	Transcriptional regulator
YPZ3_0583	COG1653	transport
YPZ3_0585	COG0395	ABC-type sugar transport system, permease component
YPZ3_0589	COG1289	transmembrane transporter activity
YPZ3_0595	COG0251	oxidation-reduction process
YPZ3_0604	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPZ3_0605	COG0358	DNA primase activity
YPZ3_0608	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPZ3_0611	COG4991	sh3 domain protein
YPZ3_0612	COG3025	triphosphatase activity
YPZ3_0615	COG0531	amino acid
YPZ3_0617	COG3384	dioxygenase
YPZ3_0618	COG0754	glutathionylspermidine amidase activity
YPZ3_0620	COG1538	Outer membrane efflux protein
YPZ3_0621	COG0494	nUDIX hydrolase
YPZ3_0622	COG3151	Protein conserved in bacteria
YPZ3_0623	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPZ3_0624	COG3150	esterase
YPZ3_0625	COG0187	DNA topoisomerase II activity
YPZ3_0626	COG0583	DNA-binding transcription factor activity
YPZ3_0627	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPZ3_0628	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPZ3_0629	COG0204	Acyl-transferase
YPZ3_0630	COG2132	Multicopper oxidase
YPZ3_0633	COG0656	L-ascorbic acid biosynthetic process
YPZ3_0634	COG1979	alcohol dehydrogenase
YPZ3_0635	COG2207	Transcriptional regulator
YPZ3_0636	COG0586	Pfam SNARE associated Golgi protein
YPZ3_0637	COG0626	cystathionine gamma-synthase activity
YPZ3_0638	COG0811	peptide transport
YPZ3_0639	COG0848	biopolymer transport protein
YPZ3_0648	COG4964	Belongs to the GSP D family
YPZ3_0649	COG4964	Belongs to the GSP D family
YPZ3_0652	COG1943	Transposase
YPZ3_0653	COG1943	Transposase
YPZ3_0657	COG4592	Periplasmic binding protein
YPZ3_0661	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPZ3_0662	COG1684	flagellar biosynthetic protein fliR
YPZ3_0666	COG2204	response regulator
YPZ3_0674	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPZ3_0675	COG1815	bacterial-type flagellum-dependent cell motility
YPZ3_0676	COG1558	bacterial-type flagellum-dependent cell motility
YPZ3_0677	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPZ3_0678	COG1749	Flagellar hook protein flgE
YPZ3_0681	COG4786	Flagellar basal body rod
YPZ3_0682	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YPZ3_0683	COG1706	bacterial-type flagellum-dependent cell motility
YPZ3_0684	COG1256	bacterial-type flagellum assembly
YPZ3_0688	COG3710	Transcriptional regulator
YPZ3_0692	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YPZ3_0697	COG1191	sigma factor activity
YPZ3_0698	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPZ3_0703	COG2801	Transposase and inactivated derivatives
YPZ3_0704	COG3300	MHYT domain
YPZ3_0704	COG5001	Diguanylate cyclase
YPZ3_0705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_0713	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPZ3_0714	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPZ3_0715	COG4771	TonB-dependent receptor
YPZ3_0720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPZ3_0720	COG3433	isochorismatase activity
YPZ3_0720	COG2226	methyltransferase
YPZ3_0721	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPZ3_0722	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPZ3_0722	COG2226	methyltransferase
YPZ3_0722	COG3433	isochorismatase activity
YPZ3_0728	COG1132	(ABC) transporter
YPZ3_0731	COG2610	gluconate transmembrane transporter activity
YPZ3_0735	COG3501	Rhs element vgr protein
YPZ3_0737	COG3209	COG3209 Rhs family protein
YPZ3_0739	COG0471	metal ion transport
YPZ3_0741	COG2801	Transposase and inactivated derivatives
YPZ3_0743	COG2211	Major facilitator Superfamily
YPZ3_0753	COG2771	luxR family
YPZ3_0754	COG3916	Acyl-homoserine-lactone synthase
YPZ3_0766	COG1662	PFAM IS1 transposase
YPZ3_0768	COG1982	Orn Lys Arg decarboxylase major
YPZ3_0769	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_0770	COG1129	ABC transporter
YPZ3_0771	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_0772	COG4774	siderophore transport
YPZ3_0775	COG1194	a g-specific adenine glycosylase
YPZ3_0777	COG3171	Protein conserved in bacteria
YPZ3_0778	COG2066	Belongs to the glutaminase family
YPZ3_0780	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPZ3_0780	COG1073	alpha beta
YPZ3_0780	COG3064	Membrane
YPZ3_0781	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPZ3_0782	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPZ3_0784	COG0762	integral membrane protein
YPZ3_0785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPZ3_0786	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPZ3_0787	COG2805	Type II/IV secretion system protein
YPZ3_0789	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPZ3_0792	COG0189	ligase activity
YPZ3_0793	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPZ3_0794	COG2356	endonuclease I
YPZ3_0797	COG1166	arginine decarboxylase activity
YPZ3_0799	COG0501	Belongs to the peptidase M48B family
YPZ3_0800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPZ3_0804	COG0191	fructose-bisphosphate aldolase activity
YPZ3_0809	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPZ3_0810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPZ3_0811	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPZ3_0814	COG0006	proline dipeptidase activity
YPZ3_0815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPZ3_0816	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPZ3_0821	COG5295	Hep Hag repeat protein
YPZ3_0823	COG1272	protein, Hemolysin III
YPZ3_0827	COG0745	RESPONSE REGULATOR receiver
YPZ3_0828	COG2205	protein histidine kinase activity
YPZ3_0829	COG4452	Inner membrane protein CreD
YPZ3_0830	COG0716	FMN binding
YPZ3_0831	COG4974	Belongs to the 'phage' integrase family
YPZ3_0832	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPZ3_0833	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPZ3_0836	COG0582	viral genome integration into host DNA
YPZ3_0838	COG2944	sequence-specific DNA binding
YPZ3_0850	COG1695	Transcriptional regulator
YPZ3_0851	COG0791	NLP P60 protein
YPZ3_0853	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_0854	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_0855	COG1129	ABC transporter
YPZ3_0857	COG2182	Extracellular solute-binding protein
YPZ3_0858	COG1175	transmembrane transport
YPZ3_0859	COG3833	ABC-type maltose transport systems, permease component
YPZ3_0860	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPZ3_0861	COG1874	Beta-galactosidase
YPZ3_0862	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_0862	COG1263	PTS System
YPZ3_0866	COG2271	Major facilitator Superfamily
YPZ3_0869	COG0191	fructose-bisphosphate aldolase activity
YPZ3_0871	COG3119	arylsulfatase activity
YPZ3_0872	COG0641	radical SAM
YPZ3_0874	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_0876	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_0877	COG3716	PTS system mannose fructose sorbose family IID component
YPZ3_0878	COG3715	PTS system
YPZ3_0879	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_0880	COG2222	sugar isomerase
YPZ3_0882	COG1349	DNA-binding transcription factor activity
YPZ3_0883	COG3119	arylsulfatase activity
YPZ3_0884	COG1943	Transposase
YPZ3_0890	COG0288	reversible hydration of carbon dioxide
YPZ3_0903	COG0840	transmembrane signaling receptor activity
YPZ3_0906	COG0583	DNA-binding transcription factor activity
YPZ3_0907	COG2814	Major facilitator Superfamily
YPZ3_0908	COG0583	DNA-binding transcription factor activity
YPZ3_0909	COG0019	diaminopimelate decarboxylase activity
YPZ3_0910	COG1609	Transcriptional regulator
YPZ3_0914	COG0667	Aldo Keto reductase
YPZ3_0926	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPZ3_0928	COG1074	ATP-dependent DNA helicase activity
YPZ3_0929	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPZ3_0931	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPZ3_0932	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPZ3_0933	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPZ3_0934	COG2166	iron-sulfur cluster assembly
YPZ3_0935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPZ3_0936	COG0583	DNA-binding transcription factor activity
YPZ3_0937	COG2363	Small membrane protein
YPZ3_0939	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPZ3_0940	COG1611	Belongs to the LOG family
YPZ3_0943	COG1943	Transposase
YPZ3_0944	COG3098	single-species biofilm formation
YPZ3_0945	COG0564	pseudouridine synthase activity
YPZ3_0950	COG0024	Methionine aminopeptidase
YPZ3_0956	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YPZ3_0957	COG0575	Belongs to the CDS family
YPZ3_0958	COG0750	zinc metalloprotease
YPZ3_0960	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YPZ3_0964	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPZ3_0966	COG0587	DNA-directed DNA polymerase activity
YPZ3_0968	COG0346	lactoylglutathione lyase activity
YPZ3_0969	COG0037	tRNA processing
YPZ3_0971	COG4681	YaeQ
YPZ3_0973	COG3015	lipoprotein NlpE involved in copper resistance
YPZ3_0975	COG1720	tRNA m6t6A37 methyltransferase activity
YPZ3_0977	COG1464	Belongs to the NlpA lipoprotein family
YPZ3_0978	COG2011	ABC-type metal ion transport system permease component
YPZ3_0980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPZ3_0981	COG0656	L-ascorbic acid biosynthetic process
YPZ3_0984	COG0741	lytic transglycosylase activity
YPZ3_0984	COG1388	LysM domain
YPZ3_0986	COG2226	methyltransferase
YPZ3_0988	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPZ3_0989	COG1953	Uracil, thiamine, allantoin
YPZ3_0998	COG0582	viral genome integration into host DNA
YPZ3_1001	COG2867	negative regulation of translational initiation
YPZ3_1002	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPZ3_1003	COG0497	DNA recombination
YPZ3_1004	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPZ3_1007	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPZ3_1008	COG1053	succinate dehydrogenase
YPZ3_1010	COG0567	Dehydrogenase, E1 component
YPZ3_1011	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPZ3_1013	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPZ3_1014	COG1271	oxidase subunit
YPZ3_1015	COG1294	oxidase, subunit
YPZ3_1016	COG0811	peptide transport
YPZ3_1017	COG0848	biopolymer transport protein
YPZ3_1018	COG3064	Membrane
YPZ3_1018	COG3064	Membrane
YPZ3_1020	COG2885	chlorophyll binding
YPZ3_1021	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPZ3_1024	COG1230	cation diffusion facilitator family transporter
YPZ3_1025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPZ3_1030	COG2017	converts alpha-aldose to the beta-anomer
YPZ3_1032	COG1085	galactose-1-phosphate uridylyltransferase
YPZ3_1033	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPZ3_1035	COG1119	ATPase activity
YPZ3_1036	COG2005	Transcriptional regulator
YPZ3_1036	COG3585	molybdate ion transport
YPZ3_1037	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPZ3_1038	COG4149	molybdate abc transporter
YPZ3_1040	COG0561	phosphatase activity
YPZ3_1045	COG2226	methyltransferase
YPZ3_1046	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPZ3_1048	COG0556	nucleotide-excision repair
YPZ3_1049	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPZ3_1050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPZ3_1052	COG0314	molybdopterin synthase activity
YPZ3_1053	COG0670	Belongs to the BI1 family
YPZ3_1054	COG1943	Transposase
YPZ3_1058	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPZ3_1059	COG0583	DNA-binding transcription factor activity
YPZ3_1061	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPZ3_1062	COG2211	Major facilitator Superfamily
YPZ3_1064	COG2211	Major facilitator Superfamily
YPZ3_1068	COG1902	pentaerythritol trinitrate reductase activity
YPZ3_1071	COG0842	Transport permease protein
YPZ3_1072	COG0842	Transport permease protein
YPZ3_1073	COG1131	(ABC) transporter
YPZ3_1075	COG1309	transcriptional regulator
YPZ3_1076	COG0513	Belongs to the DEAD box helicase family
YPZ3_1078	COG3328	transposase activity
YPZ3_1080	COG0513	Belongs to the DEAD box helicase family
YPZ3_1083	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPZ3_1084	COG1686	Belongs to the peptidase S11 family
YPZ3_1085	COG0277	FAD linked oxidase domain protein
YPZ3_1087	COG1403	HNH endonuclease
YPZ3_1090	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPZ3_1093	COG4807	Protein conserved in bacteria
YPZ3_1097	COG1122	ATPase activity
YPZ3_1098	COG0410	ABC transporter
YPZ3_1101	COG2897	thiosulfate sulfurtransferase activity
YPZ3_1102	COG1732	Glycine betaine
YPZ3_1103	COG1732	Glycine betaine
YPZ3_1104	COG1174	glycine betaine transport
YPZ3_1105	COG1125	glycine betaine transport
YPZ3_1106	COG1174	glycine betaine transport
YPZ3_1107	COG0531	amino acid
YPZ3_1108	COG1982	Orn Lys Arg decarboxylase major
YPZ3_1109	COG0697	spore germination
YPZ3_1114	COG0814	amino acid
YPZ3_1121	COG2205	protein histidine kinase activity
YPZ3_1121	COG0784	Response regulator, receiver
YPZ3_1123	COG0642	Histidine kinase
YPZ3_1123	COG2198	Histidine kinase
YPZ3_1124	COG2198	Histidine kinase
YPZ3_1124	COG0642	Histidine kinase
YPZ3_1125	COG2223	nitrite transmembrane transporter activity
YPZ3_1126	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPZ3_1128	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPZ3_1135	COG3395	kinase activity
YPZ3_1136	COG0235	Class ii aldolase
YPZ3_1137	COG1349	DNA-binding transcription factor activity
YPZ3_1138	COG3622	Belongs to the hyi family
YPZ3_1140	COG4386	tail sheath protein
YPZ3_1147	COG3299	homolog of phage Mu protein gp47
YPZ3_1150	COG1737	Transcriptional regulator
YPZ3_1151	COG2723	6-phospho-beta-galactosidase activity
YPZ3_1154	COG3157	Type VI secretion system effector, Hcp
YPZ3_1156	COG3083	sulfuric ester hydrolase activity
YPZ3_1158	COG1943	Transposase
YPZ3_1159	COG1061	Type III restriction enzyme res subunit
YPZ3_1160	COG1187	pseudouridine synthase activity
YPZ3_1161	COG2814	Major facilitator Superfamily
YPZ3_1163	COG4172	Belongs to the ABC transporter superfamily
YPZ3_1164	COG4239	(ABC) transporter, permease
YPZ3_1165	COG4174	ABC transporter (Permease)
YPZ3_1166	COG4166	transmembrane transport
YPZ3_1167	COG2200	EAL domain
YPZ3_1168	COG0791	NLP P60 protein
YPZ3_1169	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_1170	COG0523	cobalamin synthesis protein
YPZ3_1171	COG2186	Transcriptional regulator
YPZ3_1172	COG0246	Mannitol dehydrogenase
YPZ3_1173	COG1312	Catalyzes the dehydration of D-mannonate
YPZ3_1176	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1181	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPZ3_1183	COG1129	ABC transporter
YPZ3_1184	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_1185	COG0494	nUDIX hydrolase
YPZ3_1187	COG1105	Belongs to the carbohydrate kinase PfkB family
YPZ3_1188	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_1188	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_1188	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPZ3_1189	COG3710	Transcriptional regulator
YPZ3_1192	COG3121	Chaperone
YPZ3_1193	COG3188	usher protein
YPZ3_1195	COG2855	membrane
YPZ3_1196	COG0583	DNA-binding transcription factor activity
YPZ3_1197	COG0833	amino acid
YPZ3_1199	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_1201	COG4771	TonB-dependent receptor
YPZ3_1202	COG0625	glutathione transferase activity
YPZ3_1207	COG2011	ABC-type metal ion transport system permease component
YPZ3_1208	COG1686	Belongs to the peptidase S11 family
YPZ3_1209	COG0814	amino acid
YPZ3_1210	COG1349	DNA-binding transcription factor activity
YPZ3_1211	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPZ3_1212	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_1214	COG2985	domain, Protein
YPZ3_1214	COG0569	domain protein
YPZ3_1216	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPZ3_1217	COG3842	ATPase activity
YPZ3_1218	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPZ3_1219	COG1177	transmembrane transport
YPZ3_1222	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_1225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_1226	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_1227	COG1120	ATPase activity
YPZ3_1231	COG4160	amino acid transport
YPZ3_1232	COG4215	(ABC) transporter
YPZ3_1233	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_1234	COG1126	abc transporter atp-binding protein
YPZ3_1235	COG1605	Chorismate mutase
YPZ3_1237	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_1238	COG0702	epimerase
YPZ3_1239	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPZ3_1240	COG0028	Belongs to the TPP enzyme family
YPZ3_1241	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_1243	COG2431	L-lysine efflux transmembrane transporter activity
YPZ3_1244	COG3593	DNA synthesis involved in DNA repair
YPZ3_1245	COG2990	Protein conserved in bacteria
YPZ3_1246	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_1249	COG0542	response to heat
YPZ3_1250	COG1943	Transposase
YPZ3_1252	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPZ3_1254	COG0492	ferredoxin-NADP+ reductase activity
YPZ3_1256	COG3107	peptidoglycan biosynthetic process
YPZ3_1256	COG1674	ftsk spoiiie
YPZ3_1258	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPZ3_1260	COG2814	Major facilitator Superfamily
YPZ3_1261	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPZ3_1263	COG1882	Formate acetyltransferase
YPZ3_1264	COG2116	formate transmembrane transporter activity
YPZ3_1265	COG1944	ATP diphosphatase activity
YPZ3_1266	COG0252	asparaginase activity
YPZ3_1267	COG5295	Hep Hag repeat protein
YPZ3_1267	COG5295	Hep Hag repeat protein
YPZ3_1272	COG0539	negative regulation of cytoplasmic translation
YPZ3_1273	COG2333	competence protein COMEC
YPZ3_1273	COG0658	competence protein
YPZ3_1276	COG5383	Protein conserved in bacteria
YPZ3_1278	COG3173	Aminoglycoside phosphotransferase
YPZ3_1279	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPZ3_1280	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YPZ3_1281	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YPZ3_1284	COG2989	Protein conserved in bacteria
YPZ3_1285	COG3108	Peptidase M15
YPZ3_1286	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPZ3_1287	COG1448	Aminotransferase
YPZ3_1291	COG0308	aminopeptidase N
YPZ3_1294	COG3217	Mosc domain protein beta barrel domain protein
YPZ3_1294	COG0633	Ferredoxin
YPZ3_1296	COG0488	(ABC) transporter
YPZ3_1297	COG2995	paraquat-inducible protein a
YPZ3_1298	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPZ3_1298	COG3008	intermembrane lipid transfer
YPZ3_1299	COG3009	Protein conserved in bacteria
YPZ3_1300	COG1943	Transposase
YPZ3_1301	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_1304	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_1306	COG1067	ATP-dependent peptidase activity
YPZ3_1308	COG1943	Transposase
YPZ3_1309	COG2885	chlorophyll binding
YPZ3_1309	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPZ3_1311	COG3070	regulator of competence-specific genes
YPZ3_1312	COG1289	transmembrane transporter activity
YPZ3_1313	COG3304	Inner membrane component domain
YPZ3_1314	COG0210	DNA helicase
YPZ3_1316	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YPZ3_1317	COG1832	CoA-binding protein
YPZ3_1320	COG2920	part of a sulfur-relay system
YPZ3_1324	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPZ3_1326	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_1327	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1328	COG3425	synthase
YPZ3_1330	COG1024	Enoyl-CoA hydratase
YPZ3_1331	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1333	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPZ3_1359	COG0488	(ABC) transporter
YPZ3_1361	COG3328	transposase activity
YPZ3_1363	COG0303	'Molybdopterin
YPZ3_1365	COG1136	(ABC) transporter
YPZ3_1370	COG0583	DNA-binding transcription factor activity
YPZ3_1371	COG0477	Major facilitator Superfamily
YPZ3_1373	COG2311	Membrane
YPZ3_1376	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPZ3_1377	COG2949	membrane
YPZ3_1380	COG1346	cytolysis
YPZ3_1382	COG2814	Major facilitator Superfamily
YPZ3_1386	COG1943	Transposase
YPZ3_1388	COG0489	protein tyrosine kinase activity
YPZ3_1391	COG2982	Protein involved in outer membrane biogenesis
YPZ3_1392	COG1253	flavin adenine dinucleotide binding
YPZ3_1393	COG4114	ferric iron reductase
YPZ3_1394	COG0076	glutamate decarboxylase activity
YPZ3_1395	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPZ3_1398	COG1120	ATPase activity
YPZ3_1399	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_1400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_1401	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPZ3_1404	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPZ3_1405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPZ3_1407	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPZ3_1407	COG0140	phosphoribosyl-ATP diphosphatase activity
YPZ3_1410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YPZ3_1411	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPZ3_1411	COG0131	Imidazoleglycerol-phosphate dehydratase
YPZ3_1413	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPZ3_1415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_1417	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_1418	COG1129	ABC transporter
YPZ3_1419	COG1129	ABC transporter
YPZ3_1420	COG0371	Dehydrogenase
YPZ3_1421	COG0531	amino acid
YPZ3_1422	COG2925	Exonuclease
YPZ3_1425	COG3328	transposase activity
YPZ3_1426	COG1388	LysM domain
YPZ3_1426	COG2373	Large extracellular alpha-helical protein
YPZ3_1426	COG4932	domain protein
YPZ3_1427	COG2271	Major facilitator Superfamily
YPZ3_1428	COG3011	Protein conserved in bacteria
YPZ3_1429	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1431	COG4948	Mandelate Racemase Muconate Lactonizing
YPZ3_1434	COG0534	Mate efflux family protein
YPZ3_1438	COG3122	Protein conserved in bacteria
YPZ3_1442	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPZ3_1445	COG2223	nitrite transmembrane transporter activity
YPZ3_1446	COG3328	transposase activity
YPZ3_1447	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_1450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPZ3_1451	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPZ3_1452	COG1121	(ABC) transporter
YPZ3_1453	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPZ3_1459	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YPZ3_1460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YPZ3_1460	COG0072	phenylalanine-tRNA ligase activity
YPZ3_1463	COG0386	Belongs to the glutathione peroxidase family
YPZ3_1464	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YPZ3_1472	COG0791	NLP P60 protein
YPZ3_1478	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPZ3_1478	COG0574	Belongs to the PEP-utilizing enzyme family
YPZ3_1479	COG0628	permease
YPZ3_1480	COG0247	lactate metabolic process
YPZ3_1480	COG0277	FAD linked oxidase domain protein
YPZ3_1481	COG2050	protein possibly involved in aromatic compounds catabolism
YPZ3_1482	COG0316	Belongs to the HesB IscA family
YPZ3_1483	COG0719	Fe-S assembly protein
YPZ3_1484	COG0396	ATPase activity
YPZ3_1485	COG0719	Fe-S assembly protein
YPZ3_1488	COG1376	ErfK ybiS ycfS ynhG family protein
YPZ3_1488	COG1388	LysM domain
YPZ3_1494	COG0307	riboflavin synthase, alpha
YPZ3_1495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPZ3_1496	COG2814	Major facilitator Superfamily
YPZ3_1497	COG0583	DNA-binding transcription factor activity
YPZ3_1499	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPZ3_1500	COG0791	NLP P60 protein
YPZ3_1501	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPZ3_1502	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPZ3_1503	COG0346	lactoylglutathione lyase activity
YPZ3_1505	COG1902	pentaerythritol trinitrate reductase activity
YPZ3_1506	COG1309	transcriptional regulator
YPZ3_1507	COG2194	sulfuric ester hydrolase activity
YPZ3_1508	COG4989	oxidoreductase activity
YPZ3_1510	COG3133	Outer membrane lipoprotein
YPZ3_1512	COG3895	Periplasmic Protein
YPZ3_1516	COG0625	glutathione transferase activity
YPZ3_1518	COG3104	oligopeptide transport
YPZ3_1519	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPZ3_1519	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPZ3_1520	COG4172	Belongs to the ABC transporter superfamily
YPZ3_1522	COG4171	peptide transport system, permease
YPZ3_1523	COG4168	peptide transport system, permease
YPZ3_1524	COG4166	transmembrane transport
YPZ3_1526	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPZ3_1527	COG1842	Phage shock protein A
YPZ3_1528	COG1983	PspC domain protein
YPZ3_1529	COG3106	COG3106 Predicted ATPase
YPZ3_1534	COG1943	Transposase
YPZ3_1535	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPZ3_1536	COG4948	Mandelate Racemase Muconate Lactonizing
YPZ3_1537	COG2866	Carboxypeptidase
YPZ3_1538	COG4166	transmembrane transport
YPZ3_1541	COG2755	lipolytic protein G-D-S-L family
YPZ3_1541	COG0657	acetylesterase activity
YPZ3_1543	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPZ3_1543	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPZ3_1543	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPZ3_1543	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPZ3_1545	COG1285	pathogenesis
YPZ3_1546	COG3042	response to heat
YPZ3_1547	COG3187	Heat shock protein
YPZ3_1548	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPZ3_1549	COG2911	Protein conserved in bacteria
YPZ3_1550	COG3784	Protein of unknown function (DUF1318)
YPZ3_1551	COG0246	Mannitol dehydrogenase
YPZ3_1552	COG2390	Transcriptional regulator
YPZ3_1554	COG1643	Atp-dependent helicase
YPZ3_1556	COG3591	Belongs to the peptidase S1B family
YPZ3_1557	COG3038	cytochrome b561
YPZ3_1562	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPZ3_1563	COG2205	protein histidine kinase activity
YPZ3_1564	COG0745	RESPONSE REGULATOR receiver
YPZ3_1566	COG0531	amino acid
YPZ3_1568	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPZ3_1569	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPZ3_1570	COG0589	response to stress
YPZ3_1571	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPZ3_1572	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPZ3_1576	COG1011	Hydrolase
YPZ3_1577	COG0440	acetolactate synthase activity
YPZ3_1578	COG0028	Belongs to the TPP enzyme family
YPZ3_1584	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPZ3_1585	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_1587	COG1609	Transcriptional regulator
YPZ3_1588	COG0038	chloride channel
YPZ3_1589	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPZ3_1590	COG1940	carbohydrate kinase activity
YPZ3_1591	COG0583	DNA-binding transcription factor activity
YPZ3_1592	COG2814	Major facilitator Superfamily
YPZ3_1594	COG0114	fumarate hydratase activity
YPZ3_1596	COG5339	Protein conserved in bacteria
YPZ3_1598	COG0385	Bile acid
YPZ3_1599	COG0673	inositol 2-dehydrogenase activity
YPZ3_1601	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_1603	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_1606	COG2274	protein secretion by the type I secretion system
YPZ3_1607	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_1614	COG3708	Transcriptional regulator
YPZ3_1614	COG2207	Transcriptional regulator
YPZ3_1615	COG4658	electron transport chain
YPZ3_1616	COG4659	FMN binding
YPZ3_1618	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPZ3_1619	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_1620	COG2271	Major facilitator Superfamily
YPZ3_1622	COG1966	Carbon starvation protein
YPZ3_1623	COG2879	small protein
YPZ3_1624	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPZ3_1626	COG0023	Translation Initiation Factor
YPZ3_1628	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPZ3_1629	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPZ3_1630	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_1631	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YPZ3_1632	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPZ3_1634	COG0583	DNA-binding transcription factor activity
YPZ3_1635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPZ3_1636	COG0616	signal peptide processing
YPZ3_1637	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1639	COG1187	pseudouridine synthase activity
YPZ3_1640	COG0009	L-threonylcarbamoyladenylate synthase
YPZ3_1643	COG0512	Glutamine amidotransferase of anthranilate synthase
YPZ3_1645	COG0134	indole-3-glycerol-phosphate synthase activity
YPZ3_1645	COG0135	phosphoribosylanthranilate isomerase activity
YPZ3_1649	COG3047	cAMP biosynthetic process
YPZ3_1654	COG1607	acyl-coa hydrolase
YPZ3_1655	COG3328	transposase activity
YPZ3_1656	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPZ3_1660	COG4608	Belongs to the ABC transporter superfamily
YPZ3_1661	COG0444	Belongs to the ABC transporter superfamily
YPZ3_1662	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_1663	COG0601	transmembrane transport
YPZ3_1665	COG2095	MarC family integral membrane protein
YPZ3_1666	COG1454	alcohol dehydrogenase
YPZ3_1666	COG1012	belongs to the aldehyde dehydrogenase family
YPZ3_1669	COG1435	thymidine kinase activity
YPZ3_1672	COG0745	RESPONSE REGULATOR receiver
YPZ3_1674	COG0788	formyltetrahydrofolate deformylase activity
YPZ3_1675	COG3328	transposase activity
YPZ3_1676	COG0583	DNA-binding transcription factor activity
YPZ3_1677	COG0708	Exodeoxyribonuclease III
YPZ3_1678	COG0494	nUDIX hydrolase
YPZ3_1679	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPZ3_1680	COG0709	Synthesizes selenophosphate from selenide and ATP
YPZ3_1681	COG0778	Nitroreductase
YPZ3_1682	COG0616	signal peptide processing
YPZ3_1683	COG0252	asparaginase activity
YPZ3_1684	COG1335	isochorismatase
YPZ3_1685	COG3139	Protein of unknown function (DUF1315)
YPZ3_1689	COG3713	MltA-interacting MipA family protein
YPZ3_1690	COG2766	serine protein kinase
YPZ3_1693	COG0583	DNA-binding transcription factor activity
YPZ3_1695	COG2814	Major facilitator Superfamily
YPZ3_1697	COG2719	SpoVR family
YPZ3_1703	COG1104	cysteine desulfurase activity
YPZ3_1705	COG3328	transposase activity
YPZ3_1730	COG3328	transposase activity
YPZ3_1743	COG0582	viral genome integration into host DNA
YPZ3_1745	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPZ3_1746	COG2951	lytic endotransglycosylase activity
YPZ3_1748	COG2894	cell division
YPZ3_1749	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPZ3_1750	COG0318	PFAM AMP-dependent synthetase and ligase
YPZ3_1751	COG3065	identical protein binding
YPZ3_1753	COG1199	ATP-dependent helicase activity
YPZ3_1754	COG0251	oxidation-reduction process
YPZ3_1757	COG0800	Aldolase
YPZ3_1758	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPZ3_1759	COG1737	Transcriptional regulator
YPZ3_1760	COG0469	pyruvate kinase activity
YPZ3_1761	COG1560	Kdo2-lipid A biosynthetic process
YPZ3_1762	COG0739	heme binding
YPZ3_1763	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPZ3_1765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPZ3_1770	COG0494	nUDIX hydrolase
YPZ3_1772	COG1801	Protein of unknown function DUF72
YPZ3_1773	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPZ3_1777	COG3102	Protein conserved in bacteria
YPZ3_1781	COG0728	peptidoglycan biosynthetic process
YPZ3_1783	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPZ3_1786	COG3381	protein complex oligomerization
YPZ3_1788	COG1940	carbohydrate kinase activity
YPZ3_1789	COG0584	glycerophosphoryl diester phosphodiesterase
YPZ3_1790	COG3842	ATPase activity
YPZ3_1793	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPZ3_1794	COG3833	ABC-type maltose transport systems, permease component
YPZ3_1797	COG0659	secondary active sulfate transmembrane transporter activity
YPZ3_1799	COG2912	Transglutaminase-like superfamily
YPZ3_1800	COG3094	Invasion gene expression up-regulator, SirB
YPZ3_1801	COG2890	protein-(glutamine-N5) methyltransferase activity
YPZ3_1806	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPZ3_1808	COG0012	GTP binding
YPZ3_1818	COG5002	protein histidine kinase activity
YPZ3_1826	COG0500	methyltransferase
YPZ3_1830	COG3328	transposase activity
YPZ3_1839	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_1840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPZ3_1841	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPZ3_1844	COG0402	S-adenosylhomocysteine deaminase activity
YPZ3_1851	COG0395	ABC-type sugar transport system, permease component
YPZ3_1852	COG1175	transmembrane transport
YPZ3_1854	COG0673	inositol 2-dehydrogenase activity
YPZ3_1858	COG3328	transposase activity
YPZ3_1859	COG3328	transposase activity
YPZ3_1867	COG2197	response regulator
YPZ3_1868	COG3136	membrane protein required for alginate biosynthesis
YPZ3_1870	COG1113	amino acid transport
YPZ3_1873	COG2837	iron assimilation
YPZ3_1877	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPZ3_1877	COG0506	proline dehydrogenase activity
YPZ3_1877	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPZ3_1882	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YPZ3_1884	COG1191	sigma factor activity
YPZ3_1889	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YPZ3_1890	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPZ3_1891	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPZ3_1892	COG1677	Flagellar hook-basal body complex protein FliE
YPZ3_1894	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPZ3_1896	COG1157	protein secretion by the type III secretion system
YPZ3_1897	COG2882	bacterial-type flagellum organization
YPZ3_1899	COG1580	Controls the rotational direction of flagella during chemotaxis
YPZ3_1906	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_1907	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_1908	COG1129	ABC transporter
YPZ3_1910	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_1911	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1911	COG3347	Dehydrogenase
YPZ3_1912	COG2390	Transcriptional regulator
YPZ3_1914	COG1256	bacterial-type flagellum assembly
YPZ3_1918	COG4786	Flagellar basal body rod
YPZ3_1920	COG1749	Flagellar hook protein flgE
YPZ3_1921	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPZ3_1922	COG1558	bacterial-type flagellum-dependent cell motility
YPZ3_1923	COG1815	bacterial-type flagellum-dependent cell motility
YPZ3_1925	COG2747	anti-sigma28 factor FlgM
YPZ3_1926	COG3418	PFAM FlgN family protein
YPZ3_1930	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPZ3_1931	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPZ3_1936	COG2372	response to copper ion
YPZ3_1937	COG1528	Iron-storage protein
YPZ3_1939	COG1770	oligopeptidase
YPZ3_1942	COG3141	response to X-ray
YPZ3_1943	COG0513	Belongs to the DEAD box helicase family
YPZ3_1947	COG1760	l-serine dehydratase
YPZ3_1948	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPZ3_1949	COG2368	4-hydroxyphenylacetate
YPZ3_1952	COG3971	2-oxopent-4-enoate hydratase activity
YPZ3_1954	COG3384	dioxygenase
YPZ3_1955	COG1012	belongs to the aldehyde dehydrogenase family
YPZ3_1958	COG1846	Transcriptional regulator
YPZ3_1959	COG1253	flavin adenine dinucleotide binding
YPZ3_1960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_1960	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_1961	COG3715	PTS system
YPZ3_1962	COG3716	PTS system mannose fructose sorbose family IID component
YPZ3_1966	COG3447	MASE1 domain protein
YPZ3_1966	COG5002	protein histidine kinase activity
YPZ3_1966	COG5001	Diguanylate cyclase
YPZ3_1967	COG2226	methyltransferase
YPZ3_1970	COG1113	amino acid transport
YPZ3_1971	COG2207	Transcriptional regulator
YPZ3_1972	COG1132	(ABC) transporter
YPZ3_1978	COG3328	transposase activity
YPZ3_1979	COG1917	Cupin 2, conserved barrel domain protein
YPZ3_1981	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_1983	COG1175	transmembrane transport
YPZ3_1984	COG0395	ABC-type sugar transport system, permease component
YPZ3_1985	COG3842	ATPase activity
YPZ3_1986	COG1653	transport
YPZ3_1987	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPZ3_1988	COG1988	membrane-bound metal-dependent
YPZ3_1990	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPZ3_1992	COG0823	Involved in the tonB-independent uptake of proteins
YPZ3_1993	COG2814	Major facilitator Superfamily
YPZ3_1994	COG3121	Chaperone
YPZ3_1997	COG3121	Chaperone
YPZ3_1998	COG3539	Fimbrial protein
YPZ3_2000	COG0793	Belongs to the peptidase S41A family
YPZ3_2002	COG1956	GAF domain-containing protein
YPZ3_2003	COG2995	paraquat-inducible protein a
YPZ3_2004	COG3008	intermembrane lipid transfer
YPZ3_2007	COG3121	Chaperone
YPZ3_2014	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPZ3_2016	COG5295	Hep Hag repeat protein
YPZ3_2018	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPZ3_2019	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPZ3_2020	COG0745	RESPONSE REGULATOR receiver
YPZ3_2022	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPZ3_2023	COG0840	transmembrane signaling receptor activity
YPZ3_2024	COG0840	transmembrane signaling receptor activity
YPZ3_2028	COG2964	Protein conserved in bacteria
YPZ3_2030	COG0251	oxidation-reduction process
YPZ3_2031	COG2271	Major facilitator Superfamily
YPZ3_2032	COG0835	chemotaxis
YPZ3_2033	COG0643	Histidine kinase
YPZ3_2033	COG2198	Histidine kinase
YPZ3_2034	COG1360	Flagellar Motor Protein
YPZ3_2038	COG1285	pathogenesis
YPZ3_2039	COG0840	transmembrane signaling receptor activity
YPZ3_2040	COG0840	transmembrane signaling receptor activity
YPZ3_2042	COG0604	alcohol dehydrogenase
YPZ3_2042	COG3321	synthase
YPZ3_2042	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_2044	COG1522	sequence-specific DNA binding
YPZ3_2047	COG1733	regulation of RNA biosynthetic process
YPZ3_2048	COG0702	epimerase
YPZ3_2049	COG0840	transmembrane signaling receptor activity
YPZ3_2051	COG0538	isocitrate dehydrogenase activity
YPZ3_2052	COG1187	pseudouridine synthase activity
YPZ3_2056	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPZ3_2058	COG0745	RESPONSE REGULATOR receiver
YPZ3_2060	COG2850	peptidyl-arginine hydroxylation
YPZ3_2062	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YPZ3_2064	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPZ3_2066	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPZ3_2067	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPZ3_2068	COG3134	Outer membrane lipoprotein
YPZ3_2069	COG3328	transposase activity
YPZ3_2072	COG1252	NADH dehydrogenase
YPZ3_2074	COG1472	Belongs to the glycosyl hydrolase 3 family
YPZ3_2077	COG5633	Lipoprotein
YPZ3_2078	COG0537	adenosine 5'-monophosphoramidase activity
YPZ3_2079	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPZ3_2081	COG1263	PTS System
YPZ3_2081	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_2082	COG0084	hydrolase, TatD family'
YPZ3_2083	COG0470	DNA polymerase III
YPZ3_2085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPZ3_2086	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPZ3_2087	COG1943	Transposase
YPZ3_2088	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_2089	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_2093	COG1399	metal-binding, possibly nucleic acid-binding protein
YPZ3_2096	COG0564	pseudouridine synthase activity
YPZ3_2097	COG1530	ribonuclease E activity
YPZ3_2098	COG3328	transposase activity
YPZ3_2100	COG3328	transposase activity
YPZ3_2103	COG0628	permease
YPZ3_2106	COG3916	Acyl-homoserine-lactone synthase
YPZ3_2107	COG2771	luxR family
YPZ3_2108	COG0583	DNA-binding transcription factor activity
YPZ3_2109	COG0477	Major facilitator Superfamily
YPZ3_2111	COG0667	Aldo Keto reductase
YPZ3_2116	COG1203	CRISPR-associated helicase, Cas3
YPZ3_2117	COG1518	maintenance of DNA repeat elements
YPZ3_2118	COG0668	transmembrane transport
YPZ3_2122	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPZ3_2123	COG0395	ABC-type sugar transport system, permease component
YPZ3_2126	COG1609	Transcriptional regulator
YPZ3_2128	COG3842	ATPase activity
YPZ3_2130	COG3210	domain, Protein
YPZ3_2131	COG3210	domain, Protein
YPZ3_2133	COG3210	domain, Protein
YPZ3_2134	COG2831	hemolysin activation secretion protein
YPZ3_2135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_2136	COG4638	Rieske (2fe-2S)
YPZ3_2137	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPZ3_2138	COG0473	3-isopropylmalate dehydrogenase activity
YPZ3_2139	COG0583	DNA-binding transcription factor activity
YPZ3_2140	COG1609	Transcriptional regulator
YPZ3_2141	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_2142	COG1129	ABC transporter
YPZ3_2143	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_2144	COG1063	alcohol dehydrogenase
YPZ3_2148	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPZ3_2154	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_2155	COG0765	amino acid transport
YPZ3_2156	COG1126	abc transporter atp-binding protein
YPZ3_2161	COG2271	Major facilitator Superfamily
YPZ3_2163	COG2831	hemolysin activation secretion protein
YPZ3_2164	COG0747	negative chemotaxis
YPZ3_2165	COG0601	transmembrane transport
YPZ3_2166	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_2167	COG0444	Belongs to the ABC transporter superfamily
YPZ3_2168	COG4608	Belongs to the ABC transporter superfamily
YPZ3_2169	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPZ3_2170	COG2199	diguanylate cyclase activity
YPZ3_2170	COG2200	EAL domain
YPZ3_2171	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPZ3_2175	COG0612	Peptidase, M16
YPZ3_2176	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_2177	COG2200	EAL domain
YPZ3_2178	COG2982	Protein involved in outer membrane biogenesis
YPZ3_2179	COG2134	cdp-diacylglycerol pyrophosphatase
YPZ3_2180	COG1295	ribonuclease BN
YPZ3_2185	COG1929	Belongs to the glycerate kinase type-1 family
YPZ3_2186	COG2610	gluconate transmembrane transporter activity
YPZ3_2187	COG3835	regulator
YPZ3_2188	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPZ3_2189	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPZ3_2190	COG0339	signal peptide processing
YPZ3_2194	COG0589	response to stress
YPZ3_2197	COG0306	phosphate transporter
YPZ3_2198	COG2081	HI0933 family
YPZ3_2201	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_2202	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_2204	COG0191	fructose-bisphosphate aldolase activity
YPZ3_2206	COG0745	RESPONSE REGULATOR receiver
YPZ3_2207	COG1741	Belongs to the pirin family
YPZ3_2208	COG1609	Transcriptional regulator
YPZ3_2209	COG2610	gluconate transmembrane transporter activity
YPZ3_2210	COG3265	gluconokinase activity
YPZ3_2212	COG2095	MarC family integral membrane protein
YPZ3_2213	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPZ3_2215	COG3275	phosphorelay sensor kinase activity
YPZ3_2218	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
YPZ3_2220	COG0058	SHG alpha-glucan phosphorylase activity
YPZ3_2221	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPZ3_2223	COG2801	Transposase and inactivated derivatives
YPZ3_2228	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPZ3_2231	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPZ3_2234	COG1169	isochorismate synthase
YPZ3_2236	COG4575	ribosome binding
YPZ3_2237	COG0129	dihydroxy-acid dehydratase activity
YPZ3_2240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPZ3_2241	COG1609	Transcriptional regulator
YPZ3_2243	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_2244	COG3265	gluconokinase activity
YPZ3_2245	COG2731	YhcH YjgK YiaL family protein
YPZ3_2248	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPZ3_2249	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPZ3_2251	COG0839	Belongs to the complex I subunit 6 family
YPZ3_2254	COG1034	ATP synthesis coupled electron transport
YPZ3_2256	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
YPZ3_2258	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPZ3_2260	COG0583	DNA-binding transcription factor activity
YPZ3_2261	COG0436	Aminotransferase
YPZ3_2263	COG0490	domain, Protein
YPZ3_2263	COG0471	metal ion transport
YPZ3_2264	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_2268	COG0857	belongs to the CobB CobQ family
YPZ3_2268	COG0280	phosphate acetyltransferase
YPZ3_2269	COG1609	Transcriptional regulator
YPZ3_2271	COG3328	transposase activity
YPZ3_2272	COG4953	penicillin-binding protein 1C
YPZ3_2273	COG2373	Large extracellular alpha-helical protein
YPZ3_2277	COG3962	Belongs to the TPP enzyme family
YPZ3_2278	COG0673	inositol 2-dehydrogenase activity
YPZ3_2279	COG0673	inositol 2-dehydrogenase activity
YPZ3_2280	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_2281	COG1129	ABC transporter
YPZ3_2282	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_2283	COG0673	inositol 2-dehydrogenase activity
YPZ3_2284	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_2286	COG3718	enzyme involved in inositol metabolism
YPZ3_2288	COG5265	(ABC) transporter
YPZ3_2290	COG2197	response regulator
YPZ3_2292	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPZ3_2295	COG1686	Belongs to the peptidase S11 family
YPZ3_2296	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPZ3_2297	COG0772	Belongs to the SEDS family
YPZ3_2298	COG0768	penicillin binding
YPZ3_2300	COG0799	negative regulation of ribosome biogenesis
YPZ3_2302	COG1466	dna polymerase III delta subunit
YPZ3_2305	COG2888	peptidyl-tyrosine sulfation
YPZ3_2306	COG1126	abc transporter atp-binding protein
YPZ3_2307	COG0765	amino acid transport
YPZ3_2308	COG0765	amino acid transport
YPZ3_2310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPZ3_2311	COG4535	Mg2 and Co2 transporter CorC
YPZ3_2313	COG1702	phosphate starvation-inducible protein PhoH
YPZ3_2315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPZ3_2316	COG0367	asparagine synthase
YPZ3_2317	COG0647	UMP catabolic process
YPZ3_2318	COG1846	Transcriptional regulator
YPZ3_2318	COG1940	carbohydrate kinase activity
YPZ3_2319	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPZ3_2321	COG2190	(PTS) system
YPZ3_2321	COG1263	PTS System
YPZ3_2321	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_2322	COG1943	Transposase
YPZ3_2327	COG0735	belongs to the Fur family
YPZ3_2329	COG0596	Alpha beta hydrolase
YPZ3_2330	COG0582	viral genome integration into host DNA
YPZ3_2334	COG2113	Glycine betaine
YPZ3_2335	COG4176	ABC-type proline glycine betaine transport system permease component
YPZ3_2336	COG4175	Glycine betaine
YPZ3_2337	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPZ3_2344	COG0747	negative chemotaxis
YPZ3_2346	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_2347	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPZ3_2348	COG1124	(ABC) transporter
YPZ3_2354	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPZ3_2356	COG4413	Urea transporter
YPZ3_2357	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPZ3_2359	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPZ3_2360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPZ3_2361	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPZ3_2362	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPZ3_2363	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPZ3_2364	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPZ3_2365	COG1917	Cupin 2, conserved barrel domain protein
YPZ3_2365	COG2169	Transcriptional regulator
YPZ3_2367	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPZ3_2368	COG0033	Phosphoglucomutase
YPZ3_2370	COG0745	RESPONSE REGULATOR receiver
YPZ3_2371	COG2205	protein histidine kinase activity
YPZ3_2375	COG3272	Protein of unknown function (DUF1722)
YPZ3_2377	COG5212	phosphodiesterase
YPZ3_2378	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPZ3_2379	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YPZ3_2380	COG1984	allophanate hydrolase subunit 2
YPZ3_2389	COG0513	Belongs to the DEAD box helicase family
YPZ3_2391	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPZ3_2393	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YPZ3_2394	COG3026	antisigma factor binding
YPZ3_2395	COG3086	response to oxidative stress
YPZ3_2398	COG0681	Belongs to the peptidase S26 family
YPZ3_2404	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPZ3_2406	COG1943	Transposase
YPZ3_2407	COG1737	Transcriptional regulator
YPZ3_2409	COG0560	Phosphoserine phosphatase
YPZ3_2410	COG0590	tRNA wobble adenosine to inosine editing
YPZ3_2416	COG2205	protein histidine kinase activity
YPZ3_2417	COG3170	Tfp pilus assembly protein FimV
YPZ3_2418	COG2204	response regulator
YPZ3_2419	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPZ3_2419	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPZ3_2420	COG0347	Belongs to the P(II) protein family
YPZ3_2421	COG2188	Transcriptional regulator
YPZ3_2422	COG2188	Transcriptional regulator
YPZ3_2423	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_2423	COG1017	nitric oxide dioxygenase activity
YPZ3_2426	COG2814	Major facilitator Superfamily
YPZ3_2427	COG3711	transcriptional antiterminator
YPZ3_2428	COG3683	transport system, periplasmic component
YPZ3_2429	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPZ3_2430	COG1943	Transposase
YPZ3_2431	COG0483	inositol monophosphate 1-phosphatase activity
YPZ3_2434	COG1104	cysteine desulfurase activity
YPZ3_2435	COG0822	iron-sulfur transferase activity
YPZ3_2437	COG0443	Heat shock 70 kDa protein
YPZ3_2438	COG0633	Ferredoxin
YPZ3_2442	COG3468	outer membrane autotransporter barrel domain protein
YPZ3_2443	COG3468	outer membrane autotransporter barrel domain protein
YPZ3_2451	COG2976	Protein conserved in bacteria
YPZ3_2452	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPZ3_2456	COG0516	GMP reductase activity
YPZ3_2456	COG0517	IMP dehydrogenase activity
YPZ3_2458	COG1943	Transposase
YPZ3_2463	COG3328	transposase activity
YPZ3_2465	COG0351	phosphomethylpyrimidine kinase
YPZ3_2470	COG3422	double-strand break repair
YPZ3_2471	COG0745	RESPONSE REGULATOR receiver
YPZ3_2472	COG2205	protein histidine kinase activity
YPZ3_2477	COG3842	ATPase activity
YPZ3_2479	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPZ3_2481	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPZ3_2482	COG1177	transmembrane transport
YPZ3_2483	COG0443	Heat shock 70 kDa protein
YPZ3_2484	COG2239	Acts as a magnesium transporter
YPZ3_2485	COG0248	Ppx GppA phosphatase
YPZ3_2486	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPZ3_2488	COG0581	inorganic phosphate transmembrane transporter activity
YPZ3_2492	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPZ3_2493	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPZ3_2496	COG1943	Transposase
YPZ3_2499	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPZ3_2500	COG4589	Belongs to the CDS family
YPZ3_2502	COG2267	carboxylic ester hydrolase activity
YPZ3_2503	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_2503	COG2453	phosphatase
YPZ3_2509	COG0667	Aldo Keto reductase
YPZ3_2510	COG0656	L-ascorbic acid biosynthetic process
YPZ3_2515	COG3328	transposase activity
YPZ3_2516	COG2850	peptidyl-arginine hydroxylation
YPZ3_2521	COG4953	penicillin-binding protein 1C
YPZ3_2522	COG3328	transposase activity
YPZ3_2524	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPZ3_2525	COG0622	Phosphoesterase
YPZ3_2527	COG1090	epimerase
YPZ3_2528	COG4598	ABC transporter
YPZ3_2529	COG4160	amino acid transport
YPZ3_2530	COG4215	(ABC) transporter
YPZ3_2531	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_2532	COG0163	prenyltransferase activity
YPZ3_2533	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPZ3_2534	COG1286	toxin biosynthetic process
YPZ3_2535	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPZ3_2536	COG0285	dihydrofolate synthase activity
YPZ3_2538	COG0586	Pfam SNARE associated Golgi protein
YPZ3_2540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPZ3_2543	COG0697	spore germination
YPZ3_2546	COG1794	racemase activity, acting on amino acids and derivatives
YPZ3_2547	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_2549	COG3101	peptidyl-lysine hydroxylation
YPZ3_2550	COG0730	response to heat
YPZ3_2553	COG2890	protein-(glutamine-N5) methyltransferase activity
YPZ3_2555	COG2062	phosphohistidine phosphatase, SixA
YPZ3_2560	COG4235	cytochrome complex assembly
YPZ3_2560	COG3088	subunit of a heme lyase
YPZ3_2561	COG3088	subunit of a heme lyase
YPZ3_2561	COG4235	cytochrome complex assembly
YPZ3_2562	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPZ3_2563	COG1138	Cytochrome C-type biogenesis protein
YPZ3_2565	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPZ3_2566	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPZ3_2567	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPZ3_2570	COG1704	LemA family
YPZ3_2572	COG2824	Alkylphosphonate utilization operon protein PhnA
YPZ3_2577	COG3501	Rhs element vgr protein
YPZ3_2589	COG3188	usher protein
YPZ3_2590	COG3328	transposase activity
YPZ3_2591	COG3188	usher protein
YPZ3_2592	COG3121	Chaperone
YPZ3_2604	COG2951	lytic endotransglycosylase activity
YPZ3_2610	COG0243	molybdopterin cofactor binding
YPZ3_2611	COG0437	4 iron, 4 sulfur cluster binding
YPZ3_2612	COG3302	dmso reductase anchor subunit
YPZ3_2613	COG3381	protein complex oligomerization
YPZ3_2619	COG3038	cytochrome b561
YPZ3_2620	COG0436	Aminotransferase
YPZ3_2625	COG0667	Aldo Keto reductase
YPZ3_2628	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPZ3_2635	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPZ3_2636	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPZ3_2638	COG2190	(PTS) system
YPZ3_2640	COG2205	protein histidine kinase activity
YPZ3_2641	COG0745	RESPONSE REGULATOR receiver
YPZ3_2642	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_2645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPZ3_2646	COG0006	proline dipeptidase activity
YPZ3_2647	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPZ3_2649	COG3850	Histidine kinase
YPZ3_2649	COG5002	protein histidine kinase activity
YPZ3_2650	COG0745	RESPONSE REGULATOR receiver
YPZ3_2653	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YPZ3_2654	COG4208	sulfate ABC transporter
YPZ3_2655	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPZ3_2656	COG4150	thiosulfate binding
YPZ3_2658	COG1737	Transcriptional regulator
YPZ3_2659	COG2731	YhcH YjgK YiaL family protein
YPZ3_2661	COG4886	Leucine-rich repeat (LRR) protein
YPZ3_2664	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPZ3_2665	COG2837	iron assimilation
YPZ3_2667	COG3111	PFAM Bacterial OB fold (BOF) protein
YPZ3_2675	COG3005	denitrification pathway
YPZ3_2676	COG3043	anaerobic respiration
YPZ3_2678	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_2678	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_2679	COG2197	response regulator
YPZ3_2680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_2682	COG1988	membrane-bound metal-dependent
YPZ3_2683	COG0641	radical SAM
YPZ3_2684	COG3119	arylsulfatase activity
YPZ3_2685	COG3842	ATPase activity
YPZ3_2686	COG1175	transmembrane transport
YPZ3_2687	COG1840	ABC-type Fe3 transport system, periplasmic component
YPZ3_2689	COG1393	Belongs to the ArsC family
YPZ3_2691	COG1876	peptidase activity
YPZ3_2694	COG2321	neutral zinc metallopeptidase
YPZ3_2696	COG1943	Transposase
YPZ3_2697	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPZ3_2699	COG2716	regulation of RNA biosynthetic process
YPZ3_2700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPZ3_2702	COG0628	permease
YPZ3_2703	COG4783	chaperone-mediated protein folding
YPZ3_2704	COG1393	Belongs to the ArsC family
YPZ3_2706	COG1943	Transposase
YPZ3_2708	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPZ3_2710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPZ3_2711	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPZ3_2712	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPZ3_2713	COG4181	ATPase activity
YPZ3_2714	COG2755	lipolytic protein G-D-S-L family
YPZ3_2715	COG0300	oxidoreductase activity
YPZ3_2716	COG3118	belongs to the thioredoxin family
YPZ3_2717	COG0330	HflC and HflK could
YPZ3_2718	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPZ3_2719	COG0789	Transcriptional regulator
YPZ3_2720	COG2217	Heavy metal translocating P-type atpase
YPZ3_2721	COG3735	TraB family
YPZ3_2722	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPZ3_2723	COG0737	Belongs to the 5'-nucleotidase family
YPZ3_2724	COG0737	Belongs to the 5'-nucleotidase family
YPZ3_2725	COG2223	nitrite transmembrane transporter activity
YPZ3_2726	COG4651	solute:proton antiporter activity
YPZ3_2726	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPZ3_2727	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_2728	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPZ3_2732	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_2733	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YPZ3_2734	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YPZ3_2741	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_2745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_2745	COG0543	2 iron, 2 sulfur cluster binding
YPZ3_2751	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPZ3_2754	COG3264	Mechanosensitive ion channel
YPZ3_2754	COG1196	nuclear chromosome segregation
YPZ3_2755	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPZ3_2756	COG1309	transcriptional regulator
YPZ3_2757	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_2758	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_2761	COG3695	enzyme binding
YPZ3_2762	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPZ3_2763	COG1946	Acyl-CoA thioesterase
YPZ3_2764	COG0004	ammonium transporteR
YPZ3_2765	COG0347	Belongs to the P(II) protein family
YPZ3_2766	COG1132	(ABC) transporter
YPZ3_2767	COG1132	(ABC) transporter
YPZ3_2768	COG1522	sequence-specific DNA binding
YPZ3_2771	COG4533	DNA binding
YPZ3_2773	COG0824	Thioesterase
YPZ3_2774	COG1555	photosystem II stabilization
YPZ3_2775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPZ3_2776	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPZ3_2780	COG0271	Belongs to the BolA IbaG family
YPZ3_2781	COG3056	Lipoprotein
YPZ3_2782	COG2223	nitrite transmembrane transporter activity
YPZ3_2784	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPZ3_2785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPZ3_2786	COG1845	cytochrome c oxidase, subunit III
YPZ3_2787	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPZ3_2789	COG2814	Major facilitator Superfamily
YPZ3_2791	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPZ3_2792	COG0693	protein deglycase activity
YPZ3_2794	COG0142	geranyltranstransferase activity
YPZ3_2797	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPZ3_2798	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPZ3_2801	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPZ3_2801	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPZ3_2806	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPZ3_2807	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPZ3_2808	COG1862	Preprotein translocase
YPZ3_2810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YPZ3_2811	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YPZ3_2812	COG0450	alkyl hydroperoxide reductase
YPZ3_2813	COG1943	Transposase
YPZ3_2816	COG0366	Alpha amylase catalytic
YPZ3_2818	COG1114	Component of the transport system for branched-chain amino acids
YPZ3_2820	COG5002	protein histidine kinase activity
YPZ3_2821	COG0745	RESPONSE REGULATOR receiver
YPZ3_2822	COG0420	3'-5' exonuclease activity
YPZ3_2823	COG0419	ATPase involved in DNA repair
YPZ3_2824	COG1940	carbohydrate kinase activity
YPZ3_2828	COG2226	methyltransferase
YPZ3_2837	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPZ3_2840	COG1477	protein flavinylation
YPZ3_2844	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPZ3_2845	COG1805	sodium ion transport
YPZ3_2846	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPZ3_2847	COG3034	peptidoglycan biosynthetic process
YPZ3_2848	COG0121	glutamine amidotransferase
YPZ3_2850	COG1960	acyl-CoA dehydrogenase activity
YPZ3_2852	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPZ3_2856	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPZ3_2859	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPZ3_2867	COG2814	Major facilitator Superfamily
YPZ3_2868	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPZ3_2870	COG1846	Transcriptional regulator
YPZ3_2871	COG1566	PFAM secretion protein HlyD family protein
YPZ3_2872	COG2814	Major facilitator Superfamily
YPZ3_2873	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPZ3_2874	COG3118	belongs to the thioredoxin family
YPZ3_2876	COG1042	CoA-binding domain protein
YPZ3_2876	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPZ3_2876	COG0045	succinate-CoA ligase (ADP-forming) activity
YPZ3_2877	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPZ3_2878	COG5544	Lipoprotein
YPZ3_2880	COG0542	response to heat
YPZ3_2882	COG0564	pseudouridine synthase activity
YPZ3_2883	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPZ3_2884	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPZ3_2885	COG1943	Transposase
YPZ3_2886	COG1605	Chorismate mutase
YPZ3_2886	COG0077	Prephenate dehydratase
YPZ3_2889	COG1605	Chorismate mutase
YPZ3_2889	COG0077	Prephenate dehydratase
YPZ3_2890	COG0287	Prephenate dehydrogenase
YPZ3_2890	COG1605	Chorismate mutase
YPZ3_2891	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPZ3_2892	COG3279	Response regulator of the LytR AlgR family
YPZ3_2893	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPZ3_2894	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPZ3_2895	COG3137	Salt-induced outer membrane protein
YPZ3_2900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPZ3_2901	COG4137	Cytochrome C assembly protein
YPZ3_2902	COG4536	flavin adenine dinucleotide binding
YPZ3_2905	COG2918	glutathione biosynthetic process
YPZ3_2906	COG1238	metal cluster binding
YPZ3_2907	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_2915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPZ3_2916	COG3958	Transketolase
YPZ3_2917	COG3959	Transketolase, thiamine diphosphate binding domain
YPZ3_2918	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_2919	COG1129	ABC transporter
YPZ3_2923	COG3783	Cytochrome b(562)
YPZ3_2924	COG3381	protein complex oligomerization
YPZ3_2925	COG3302	dmso reductase anchor subunit
YPZ3_2926	COG0437	4 iron, 4 sulfur cluster binding
YPZ3_2927	COG0243	molybdopterin cofactor binding
YPZ3_2928	COG0235	Class ii aldolase
YPZ3_2929	COG1349	DNA-binding transcription factor activity
YPZ3_2931	COG1943	Transposase
YPZ3_2932	COG1129	ABC transporter
YPZ3_2933	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_2934	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_2935	COG3623	hexulose-6-phosphate isomerase
YPZ3_2936	COG1070	Carbohydrate kinase
YPZ3_2937	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPZ3_2937	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPZ3_2938	COG0024	Methionine aminopeptidase
YPZ3_2941	COG4771	TonB-dependent receptor
YPZ3_2942	COG1858	cytochrome C peroxidase
YPZ3_2943	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_2945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPZ3_2947	COG2390	Transcriptional regulator
YPZ3_2949	COG2376	Dihydroxyacetone kinase
YPZ3_2950	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_2951	COG1063	alcohol dehydrogenase
YPZ3_2952	COG0698	ribose 5-phosphate isomerase
YPZ3_2953	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YPZ3_2954	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPZ3_2955	COG4942	peptidase
YPZ3_2955	COG1388	LysM domain
YPZ3_2960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YPZ3_2963	COG0529	Catalyzes the synthesis of activated sulfate
YPZ3_2971	COG0720	synthase
YPZ3_2972	COG0602	queuosine metabolic process
YPZ3_2976	COG3956	TIGRFAM MazG family protein
YPZ3_2977	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPZ3_2978	COG2205	protein histidine kinase activity
YPZ3_2978	COG3437	response regulator, receiver
YPZ3_2978	COG3850	Histidine kinase
YPZ3_2978	COG4999	Histidine kinase
YPZ3_2979	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPZ3_2981	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPZ3_2983	COG2860	membrane
YPZ3_2987	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_2988	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPZ3_2989	COG1120	ATPase activity
YPZ3_2990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPZ3_2991	COG1643	Atp-dependent helicase
YPZ3_2992	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPZ3_2994	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YPZ3_2995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YPZ3_2996	COG0617	tRNA 3'-terminal CCA addition
YPZ3_2997	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPZ3_3001	COG0726	polysaccharide deacetylase
YPZ3_3002	COG0842	Transport permease protein
YPZ3_3003	COG1131	(ABC) transporter
YPZ3_3004	COG0288	reversible hydration of carbon dioxide
YPZ3_3005	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPZ3_3006	COG2132	Multicopper oxidase
YPZ3_3010	COG0697	spore germination
YPZ3_3012	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPZ3_3013	COG1943	Transposase
YPZ3_3014	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPZ3_3015	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPZ3_3016	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPZ3_3017	COG2186	Transcriptional regulator
YPZ3_3018	COG1113	amino acid transport
YPZ3_3019	COG3725	Membrane protein required for beta-lactamase induction
YPZ3_3020	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPZ3_3022	COG4969	Belongs to the N-Me-Phe pilin family
YPZ3_3023	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPZ3_3024	COG1459	type II secretion system
YPZ3_3026	COG0237	dephospho-CoA kinase activity
YPZ3_3028	COG1943	Transposase
YPZ3_3033	COG0582	viral genome integration into host DNA
YPZ3_3034	COG0795	lipopolysaccharide-transporting ATPase activity
YPZ3_3035	COG0795	lipopolysaccharide-transporting ATPase activity
YPZ3_3037	COG2927	DNA polymerase III (CHI subunit)
YPZ3_3038	COG0525	valine-tRNA ligase activity
YPZ3_3040	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPZ3_3041	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YPZ3_3042	COG2731	YhcH YjgK YiaL family protein
YPZ3_3045	COG0601	transmembrane transport
YPZ3_3046	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_3047	COG0444	Belongs to the ABC transporter superfamily
YPZ3_3048	COG4608	Belongs to the ABC transporter superfamily
YPZ3_3051	COG2188	Transcriptional regulator
YPZ3_3052	COG3624	Phosphonate C-P lyase system protein PhnG
YPZ3_3053	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPZ3_3054	COG3626	phosphonate metabolism
YPZ3_3055	COG3627	carbon phosphorus lyase activity
YPZ3_3056	COG4107	phosphonate C-P lyase system protein PhnK
YPZ3_3057	COG4778	phosphonate C-P lyase system protein PhnL
YPZ3_3058	COG3454	Phosphonate metabolism
YPZ3_3059	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPZ3_3060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPZ3_3061	COG0702	epimerase
YPZ3_3064	COG3842	ATPase activity
YPZ3_3065	COG0395	ABC-type sugar transport system, permease component
YPZ3_3067	COG1653	transport
YPZ3_3070	COG3153	acetyltransferase
YPZ3_3075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_3077	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPZ3_3079	COG0513	Belongs to the DEAD box helicase family
YPZ3_3082	COG2801	Transposase and inactivated derivatives
YPZ3_3097	COG3501	Rhs element vgr protein
YPZ3_3100	COG3209	COG3209 Rhs family protein
YPZ3_3103	COG3501	Rhs element vgr protein
YPZ3_3105	COG3209	COG3209 Rhs family protein
YPZ3_3108	COG0673	inositol 2-dehydrogenase activity
YPZ3_3109	COG2207	Transcriptional regulator
YPZ3_3109	COG1917	Cupin 2, conserved barrel domain protein
YPZ3_3110	COG1869	D-ribose catabolic process
YPZ3_3111	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_3113	COG0431	NADPH-dependent FMN reductase
YPZ3_3114	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPZ3_3116	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPZ3_3118	COG2252	PERMEase
YPZ3_3119	COG0025	NhaP-type Na H and K H
YPZ3_3121	COG1560	Kdo2-lipid A biosynthetic process
YPZ3_3123	COG1129	ABC transporter
YPZ3_3124	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_3126	COG1069	ribulokinase activity
YPZ3_3128	COG0625	glutathione transferase activity
YPZ3_3132	COG3133	Outer membrane lipoprotein
YPZ3_3133	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPZ3_3135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPZ3_3139	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPZ3_3141	COG4145	pantothenate transmembrane transporter activity
YPZ3_3142	COG0439	Biotin carboxylase
YPZ3_3143	COG0511	ligase activity, forming carbon-carbon bonds
YPZ3_3146	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YPZ3_3147	COG0604	alcohol dehydrogenase
YPZ3_3148	COG2200	EAL domain
YPZ3_3148	COG2199	diguanylate cyclase activity
YPZ3_3149	COG1077	Cell shape determining protein MreB Mrl
YPZ3_3150	COG1792	Involved in formation and maintenance of cell shape
YPZ3_3151	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPZ3_3153	COG1530	ribonuclease E activity
YPZ3_3154	COG3164	Protein of unknown function
YPZ3_3155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPZ3_3156	COG0312	modulator of DNA gyrase
YPZ3_3167	COG0583	DNA-binding transcription factor activity
YPZ3_3170	COG1012	belongs to the aldehyde dehydrogenase family
YPZ3_3174	COG0312	modulator of DNA gyrase
YPZ3_3176	COG3783	Cytochrome b(562)
YPZ3_3177	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPZ3_3178	COG0366	Alpha amylase catalytic
YPZ3_3179	COG1263	PTS System
YPZ3_3179	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_3180	COG1609	Transcriptional regulator
YPZ3_3186	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_3187	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPZ3_3188	COG1137	ATPase activity
YPZ3_3189	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPZ3_3190	COG3117	lipopolysaccharide transmembrane transporter activity
YPZ3_3191	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPZ3_3192	COG0517	IMP dehydrogenase activity
YPZ3_3192	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPZ3_3193	COG0530	calcium, potassium:sodium antiporter activity
YPZ3_3194	COG1127	ABC transporter
YPZ3_3195	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPZ3_3196	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPZ3_3197	COG2854	intermembrane phospholipid transfer
YPZ3_3198	COG3113	response to antibiotic
YPZ3_3200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPZ3_3201	COG1943	Transposase
YPZ3_3202	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPZ3_3203	COG3105	Protein conserved in bacteria
YPZ3_3204	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPZ3_3207	COG0625	glutathione transferase activity
YPZ3_3208	COG2969	positive regulation of protein catabolic process
YPZ3_3210	COG0493	'glutamate synthase
YPZ3_3211	COG0069	glutamate synthase activity
YPZ3_3211	COG0067	glutamate synthase
YPZ3_3211	COG0070	glutamate synthase
YPZ3_3212	COG1242	4 iron, 4 sulfur cluster binding
YPZ3_3213	COG5002	protein histidine kinase activity
YPZ3_3213	COG2198	Histidine kinase
YPZ3_3213	COG0784	Response regulator, receiver
YPZ3_3214	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPZ3_3216	COG2823	Periplasmic or secreted lipoprotein
YPZ3_3220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPZ3_3221	COG1741	Belongs to the pirin family
YPZ3_3222	COG0583	DNA-binding transcription factor activity
YPZ3_3223	COG0435	Glutathione S-transferase
YPZ3_3226	COG1073	alpha beta
YPZ3_3227	COG0360	Binds together with S18 to 16S ribosomal RNA
YPZ3_3229	COG1943	Transposase
YPZ3_3231	COG3061	Opacity-associated protein A
YPZ3_3232	COG0545	Peptidyl-prolyl cis-trans isomerase
YPZ3_3234	COG0737	Belongs to the 5'-nucleotidase family
YPZ3_3236	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPZ3_3237	COG1253	flavin adenine dinucleotide binding
YPZ3_3239	COG0729	surface antigen
YPZ3_3240	COG2911	Protein conserved in bacteria
YPZ3_3241	COG2105	PFAM AIG2 family protein
YPZ3_3242	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPZ3_3244	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPZ3_3248	COG0142	geranyltranstransferase activity
YPZ3_3250	COG0697	spore germination
YPZ3_3252	COG0642	Histidine kinase
YPZ3_3253	COG0745	RESPONSE REGULATOR receiver
YPZ3_3254	COG2027	D-alanyl-D-alanine carboxypeptidase
YPZ3_3255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPZ3_3257	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YPZ3_3258	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPZ3_3261	COG0195	Participates in both transcription termination and antitermination
YPZ3_3266	COG2801	Transposase and inactivated derivatives
YPZ3_3275	COG1175	transmembrane transport
YPZ3_3276	COG3833	ABC-type maltose transport systems, permease component
YPZ3_3279	COG0527	aspartate kinase activity
YPZ3_3284	COG1414	Transcriptional regulator
YPZ3_3285	COG1414	Transcriptional regulator
YPZ3_3287	COG2224	Isocitrate lyase
YPZ3_3288	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPZ3_3291	COG0151	Belongs to the GarS family
YPZ3_3293	COG3068	Protein conserved in bacteria
YPZ3_3294	COG1515	deoxyribonuclease V activity
YPZ3_3299	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YPZ3_3301	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPZ3_3304	COG1943	Transposase
YPZ3_3311	COG0250	Participates in transcription elongation, termination and antitermination
YPZ3_3312	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPZ3_3319	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YPZ3_3320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPZ3_3321	COG1739	Uncharacterized protein family UPF0029
YPZ3_3334	COG0805	protein transport
YPZ3_3339	COG1322	Protein conserved in bacteria
YPZ3_3340	COG0586	Pfam SNARE associated Golgi protein
YPZ3_3341	COG1966	Carbon starvation protein
YPZ3_3343	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YPZ3_3344	COG0412	Dienelactone hydrolase
YPZ3_3346	COG0583	DNA-binding transcription factor activity
YPZ3_3347	COG0679	Auxin Efflux Carrier
YPZ3_3348	COG0584	glycerophosphoryl diester phosphodiesterase
YPZ3_3360	COG0410	ABC transporter
YPZ3_3361	COG0411	ABC transporter
YPZ3_3362	COG4177	L-phenylalanine transmembrane transporter activity
YPZ3_3363	COG0559	Belongs to the binding-protein-dependent transport system permease family
YPZ3_3364	COG0683	leucine binding
YPZ3_3366	COG1943	Transposase
YPZ3_3368	COG2177	Part of the ABC transporter FtsEX involved in
YPZ3_3369	COG2884	Cell division ATP-binding protein ftsE
YPZ3_3370	COG0552	protein localization to endoplasmic reticulum
YPZ3_3370	COG0552	protein localization to endoplasmic reticulum
YPZ3_3371	COG0742	ribosomal rna small subunit methyltransferase
YPZ3_3374	COG3714	YhhN family
YPZ3_3377	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPZ3_3379	COG0247	lactate metabolic process
YPZ3_3381	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPZ3_3382	COG0584	glycerophosphoryl diester phosphodiesterase
YPZ3_3384	COG0561	phosphatase activity
YPZ3_3385	COG2267	carboxylic ester hydrolase activity
YPZ3_3386	COG1280	lysine exporter protein (LysE YggA)
YPZ3_3387	COG1280	lysine exporter protein (LysE YggA)
YPZ3_3388	COG0514	ATP-dependent DNA helicase (RecQ)
YPZ3_3389	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPZ3_3390	COG2050	protein possibly involved in aromatic compounds catabolism
YPZ3_3392	COG0598	Magnesium transport protein CorA
YPZ3_3393	COG5564	TIM-barrel signal transduction protein
YPZ3_3394	COG5441	Belongs to the UPF0261 family
YPZ3_3396	COG0210	DNA helicase
YPZ3_3397	COG1011	Hydrolase
YPZ3_3398	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPZ3_3399	COG3159	Protein conserved in bacteria
YPZ3_3402	COG3072	Adenylate cyclase
YPZ3_3404	COG1587	Uroporphyrinogen-III synthase
YPZ3_3405	COG2959	enzyme of heme biosynthesis
YPZ3_3406	COG3071	HemY protein
YPZ3_3408	COG1113	amino acid transport
YPZ3_3412	COG2244	polysaccharide biosynthetic process
YPZ3_3413	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPZ3_3414	COG0456	acetyltransferase
YPZ3_3415	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPZ3_3416	COG1088	dTDP-glucose 4,6-dehydratase activity
YPZ3_3417	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPZ3_3418	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPZ3_3419	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPZ3_3420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPZ3_3421	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPZ3_3422	COG3118	belongs to the thioredoxin family
YPZ3_3427	COG3328	transposase activity
YPZ3_3429	COG3121	Chaperone
YPZ3_3432	COG3121	Chaperone
YPZ3_3435	COG0583	DNA-binding transcription factor activity
YPZ3_3441	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPZ3_3444	COG3085	chromosome segregation
YPZ3_3446	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_3447	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_3448	COG1129	ABC transporter
YPZ3_3449	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_3457	COG0678	peroxiredoxin activity
YPZ3_3457	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPZ3_3458	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPZ3_3463	COG1629	transport
YPZ3_3466	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YPZ3_3470	COG2801	Transposase and inactivated derivatives
YPZ3_3475	COG3276	selenocysteine insertion sequence binding
YPZ3_3478	COG2864	formate dehydrogenase
YPZ3_3479	COG0437	4 iron, 4 sulfur cluster binding
YPZ3_3480	COG0243	molybdopterin cofactor binding
YPZ3_3480	COG3383	formate dehydrogenase (NAD+) activity
YPZ3_3481	COG0243	molybdopterin cofactor binding
YPZ3_3481	COG3383	formate dehydrogenase (NAD+) activity
YPZ3_3483	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPZ3_3488	COG3722	fumarate hydratase activity
YPZ3_3490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_3490	COG2213	PTS system mannitol-specific
YPZ3_3494	COG2818	Glycosylase
YPZ3_3496	COG2885	chlorophyll binding
YPZ3_3499	COG0366	Alpha amylase catalytic
YPZ3_3501	COG3977	Valine--pyruvate aminotransferase
YPZ3_3505	COG5645	(Lipo)protein
YPZ3_3506	COG0823	Involved in the tonB-independent uptake of proteins
YPZ3_3507	COG0823	Involved in the tonB-independent uptake of proteins
YPZ3_3508	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPZ3_3509	COG2423	ornithine cyclodeaminase activity
YPZ3_3511	COG2801	Transposase and inactivated derivatives
YPZ3_3512	COG0561	phosphatase activity
YPZ3_3513	COG0187	DNA topoisomerase II activity
YPZ3_3514	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YPZ3_3515	COG0592	DNA-directed DNA polymerase activity
YPZ3_3517	COG0706	membrane insertase activity
YPZ3_3521	COG2252	PERMEase
YPZ3_3522	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_3523	COG0765	amino acid transport
YPZ3_3524	COG0765	amino acid transport
YPZ3_3525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_3527	COG0704	Plays a role in the regulation of phosphate uptake
YPZ3_3529	COG0581	inorganic phosphate transmembrane transporter activity
YPZ3_3530	COG0573	inorganic phosphate transmembrane transporter activity
YPZ3_3531	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPZ3_3532	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YPZ3_3541	COG3312	ion transport
YPZ3_pCD0001	COG2801	Transposase and inactivated derivatives
YPZ3_pCD0003	COG5599	Phosphatase
YPZ3_pCD0005	COG1475	DNA binding
YPZ3_pCD0006	COG1192	Involved in chromosome partitioning
YPZ3_pCD0007	COG2801	Transposase and inactivated derivatives
YPZ3_pCD0011	COG3177	Filamentation induced by cAMP protein fic
YPZ3_pCD0015	COG4886	Leucine-rich repeat (LRR) protein
YPZ3_pCD0019	COG0457	Tetratricopeptide repeat
YPZ3_pCD0022	COG4789	Type iii secretion
YPZ3_pCD0030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPZ3_pCD0031	COG4790	Type iii secretion
YPZ3_pCD0032	COG4791	protein targeting
YPZ3_pCD0033	COG4792	protein secretion
YPZ3_pCD0035	COG2207	Transcriptional regulator
YPZ3_pCD0043	COG4669	(LipO)protein
YPZ3_pCD0045	COG1317	bacterial-type flagellum organization
YPZ3_pCD0046	COG5599	Phosphatase
YPZ3_pCD0047	COG2801	Transposase and inactivated derivatives
YPZ3_pCD0050	COG2801	Transposase and inactivated derivatives
YPZ3_pCD0052	COG0515	serine threonine protein kinase
YPZ3_pCD0059	COG2801	Transposase and inactivated derivatives
YPZ3_pCD0064	COG2801	Transposase and inactivated derivatives
YPZ3_pMT0003	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
YPZ3_pMT0004	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPZ3_pMT0004	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPZ3_pMT0011	COG3941	tape measure
YPZ3_pMT0027	COG1475	DNA binding
YPZ3_pMT0028	COG1475	DNA binding
YPZ3_pMT0029	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPZ3_pMT0034	COG1943	Transposase
YPZ3_pMT0039	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPZ3_pMT0046	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YPZ3_pMT0047	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPZ3_pMT0061	COG3328	transposase activity
YPZ3_pMT0064	COG3344	reverse transcriptase
YPZ3_pMT0066	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPZ3_pMT0076	COG1475	DNA binding
YPZ3_pPCP0008	COG4683	PFAM Phage derived protein Gp49-like (DUF891)