locus-tag class description YPC_0001 ENOG4105QTB Flavodoxin YPC_0002 ENOG4108VVK transcriptional Regulator, AsnC YPC_0008 ENOG4108RVA ribokinase YPC_0010 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPC_0011 ENOG4107EJG GntR family transcriptional regulator YPC_0021 ENOG4107QP3 malate synthase g YPC_0022 ENOG4108I9X Isocitrate lyase YPC_0027 ENOG4105C3R Methionine synthase YPC_0032 ENOG4105CFH Aspartokinase YPC_0035 ENOG4105EG2 ABC transporter, permease YPC_0036 ENOG4105D56 permease protein YPC_0037 ENOG4107FKK extracellular solute-binding protein family 1 YPC_0041 ENOG4107W52 maltose operon periplasmic protein YPC_0044 ENOG4108WC9 type VI secretion system effector, hcp1 family YPC_0052 ENOG4105DQ6 Transposase YPC_0054 ENOG4105E98 transcriptional regulator DeoR family YPC_0060 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) YPC_0063 ENOG4105MJ2 Competence protein YPC_0065 ENOG4105RID UPF0379 protein yhcN YPC_0067 ENOG4105CE1 Ferrous iron transport protein b YPC_0068 ENOG4105XFK Ferrous iron transport protein A YPC_0070 ENOG4105BZM domain protein YPC_0071 ENOG4108RRZ Transcription elongation factor GreB YPC_0072 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPC_0073 ENOG4105E0F Histidine kinase YPC_0076 ENOG4105VEJ Heat shock protein YPC_0077 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 YPC_0078 ENOG4105DQY intracellular growth attenuator YPC_0079 ENOG4107RK2 ADP-ribose diphosphatase NudE YPC_0080 ENOG4108JQC penicillin-binding protein 1A YPC_0086 ENOG4105E4G Type IV pilus YPC_0091 ENOG4105DJV ribulose-phosphate 3-epimerase YPC_0092 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) YPC_0093 ENOG4105C31 Tryptophanyl-tRNA synthetase YPC_0095 ENOG4107V9H nitrite transporter YPC_0097 ENOG4105WZK nitrite reductase NADPH small subunit YPC_0098 ENOG4107QZF nitrite reductase NADPH large subunit YPC_0100 ENOG4105DZC cytosine deaminase YPC_0103 ENOG41060NJ transcriptional regulator YPC_0104 ENOG4105F8D glycoside hydrolase family 4 YPC_0105 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) YPC_0106 ENOG4105D7A ATP-binding protein YPC_0108 ENOG4105C8Y Acetylornithine aminotransferase YPC_0110 ENOG410613R integral membrane protein, YccS YhfK family YPC_0112 ENOG4108UKZ OsmC family YPC_0114 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) YPC_0116 ENOG4105DNZ Alpha Beta Hydrolase YPC_0119 ENOG4106FTQ Taurine ABC transporter, periplasmic YPC_0121 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component YPC_0122 ENOG4105E2B Taurine dioxygenase YPC_0124 ENOG4105K64 Glycosyl transferase, family 2 YPC_0129 ENOG4105VKU nucleicacid-binding protein YPC_0130 ENOG4108YZY peptidylprolyl cis-trans isomerase YPC_0133 ENOG4108V1T peptidylprolyl cis-trans isomerase YPC_0134 ENOG4105WWK YheO domain protein YPC_0139 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) YPC_0144 ENOG4108RS6 transposase YPC_0152 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) YPC_0154 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) YPC_0155 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) YPC_0157 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal YPC_0166 ENOG4105VPB 50S ribosomal protein L30 YPC_0168 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) YPC_0169 ENOG41067V7 50S ribosomal protein L36 YPC_0172 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) YPC_0175 ENOG4105W1Y Transcriptional regulator YPC_0176 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system YPC_0178 ENOG4105C1A potassium transporter peripheral membrane YPC_0182 ENOG4105C79 DNA protecting protein DprA YPC_0184 ENOG4108WI1 Dna topoisomerase YPC_0187 ENOG4108Z0R Transferase YPC_0190 ENOG4105SUU thioesterase domain YPC_0191 ENOG4105JV1 AsmA family YPC_0193 ENOG4105C2W permease YPC_0194 ENOG4105D6U Sodium Glutamate Symporter YPC_0196 ENOG4105CB5 ATP-dependent DNA helicase recG YPC_0197 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase YPC_0198 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) YPC_0201 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) YPC_0202 ENOG4105EN6 Membrane YPC_0203 ENOG4105DSJ YicC domain protein YPC_0208 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase YPC_0211 ENOG4105W0E 50S ribosomal protein L33 YPC_0215 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase YPC_0216 ENOG4105D16 lipopolysaccharide heptosyltransferase i YPC_0217 ENOG4105XA0 heptosyltransferase ii YPC_0219 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) YPC_0223 ENOG41063SB peptidase YPC_0225 ENOG4107YZP Rhodanese domain protein YPC_0226 ENOG4105VW4 glutaredoxin 3 YPC_0230 ENOG4105D7W serine acetyltransferase YPC_0231 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) YPC_0232 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) YPC_0233 ENOG4105E0F Histidine kinase YPC_0234 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPC_0235 ENOG4105FMW periplasmic YPC_0241 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein YPC_0243 ENOG4107QPK )-transporter YPC_0244 ENOG4105JSC dimethylmenaquinone methyltransferase YPC_0246 ENOG4107F9Y LysR family transcriptional regulator YPC_0248 ENOG4105EBK exported protein YPC_0249 ENOG4108VTS Membrane YPC_0250 ENOG4105DP0 ferredoxin-NADP reductase YPC_0251 ENOG4105CBT Fructose-1,6-bisphosphatase YPC_0252 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) YPC_0260 ENOG4108JJA ABC, transporter YPC_0261 ENOG4108MBX Secretion Protein YPC_0268 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase YPC_0271 ENOG41063M6 Cell Division Protein YPC_0272 ENOG4105ETE Transcriptional regulator (LacI family YPC_0273 ENOG4105C25 Primosomal protein n' YPC_0276 ENOG4108Z12 YiaAB two helix domain-containing protein YPC_0280 ENOG4105C28 cystathionine YPC_0281 ENOG4105C28 cystathionine YPC_0282 ENOG4105CFH Aspartokinase YPC_0283 ENOG4105SYT Methylenetetrahydrofolate reductase YPC_0284 ENOG4105DQ6 Transposase YPC_0289 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase YPC_0296 ENOG4107QZV Type I secretion membrane fusion protein YPC_0297 ENOG4105YHG TonB family YPC_0298 ENOG4107QN2 dihydrolipoyl dehydrogenase YPC_0299 ENOG4105EHV domain protein YPC_0300 ENOG4105C5Q Transcriptional regulator YPC_0303 ENOG4108Y73 Membrane YPC_0315 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator YPC_0316 ENOG4105C2J ABC transporter YPC_0320 ENOG4108WFC UPF0438 protein yifE YPC_0321 ENOG4105C0P Mg chelatase subunit ChlI YPC_0323 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit YPC_0324 ENOG4105CM2 brancheD-chain amino acid aminotransferase YPC_0326 ENOG4105C7B Threonine dehydratase YPC_0332 ENOG4105EMY transcriptional regulator YPC_0340 ENOG4108VEV chaperone YPC_0342 ENOG4105CW0 outer membrane usher protein YPC_0343 ENOG4105GQR Chaperone YPC_0347 ENOG4105KQ5 peptidylprolyl cis-trans isomerase YPC_0349 ENOG4105C4R Atp-dependent dna helicase YPC_0354 ENOG4105K63 Thioredoxin YPC_0356 ENOG4105ESV Glycosyl transferase, family 4 YPC_0357 ENOG4105SFE lipopolysaccharide biosynthesis protein YPC_0358 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase YPC_0359 ENOG4108IJ1 Dehydrogenase YPC_0360 ENOG4105C1B dTDP-glucose 4-6-dehydratase YPC_0361 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) YPC_0362 ENOG4108WJ1 acetyltransferase YPC_0363 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase YPC_0364 ENOG4105EGZ biosynthesis protein YPC_0368 ENOG4105C85 amino acid YPC_0376 ENOG410601J HemY protein YPC_0377 ENOG4105ECF c-methyltransferase YPC_0378 ENOG41076E6 Uroporphyrinogen-III Synthase YPC_0382 ENOG4107T0K Adenylate cyclase YPC_0385 ENOG4105S7Z (LipO)protein YPC_0387 ENOG4105CT0 Protein of unknown function, DUF484 YPC_0388 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPC_0389 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant YPC_0390 ENOG4105C4R Atp-dependent dna helicase YPC_0392 ENOG4105EQN UPF0261 protein YPC_0395 ENOG4107QUT magnesium and cobalt transport protein CorA YPC_0396 ENOG4105FR1 rard protein YPC_0397 ENOG4108VUY thioesterase Superfamily protein YPC_0400 ENOG4105C9U ATP-dependent DNA helicase RecQ YPC_0401 ENOG4105CCF Lysine exporter protein (Lyse ygga) YPC_0403 ENOG4108EUD Lysophospholipase YPC_0404 ENOG4105DQF Hydrolase YPC_0406 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase YPC_0411 ENOG4108W1V Lipoprotein YPC_0412 ENOG4105EX9 Membrane YPC_0416 ENOG4107FS9 Membrane YPC_0419 ENOG4105MG3 Membrane YPC_0420 ENOG4106H78 methyltransferase YPC_0421 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) YPC_0421 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) YPC_0422 ENOG4105CAK Cell division ATP-binding protein ftsE YPC_0423 ENOG4105CRP Part of the ABC transporter FtsEX involved in YPC_0427 ENOG4108RS6 transposase YPC_0428 ENOG4105U59 -acetyltransferase YPC_0430 ENOG4105CP9 extracellular ligand-binding receptor YPC_0431 ENOG4105C32 Amino acid ABC transporter (Permease) YPC_0432 ENOG4105CF8 branched-chain amino acid ABC transporter, permease YPC_0433 ENOG4105C0Z ABC transporter YPC_0434 ENOG4108IV0 ABC, transporter YPC_0447 ENOG4107T6V glycerophosphoryl diester phosphodiesterase YPC_0448 ENOG4105RK9 auxin efflux carrier YPC_0449 ENOG4105EMK carboxylate amino acid amine transporter YPC_0450 ENOG4105DZ2 Transcriptional regulator YPC_0452 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) YPC_0453 ENOG4108I5U Uridine phosphorylase YPC_0456 ENOG4108KF1 Membrane YPC_0457 ENOG4105CGY Dna recombination protein YPC_0459 ENOG4105JC1 sterol-binding domain protein YPC_0461 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) YPC_0463 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) YPC_0469 ENOG4105D52 delta-aminolevulinic acid dehydratase YPC_0470 ENOG4105MDZ Transcriptional activator rfaH YPC_0472 ENOG4107QK7 reductase YPC_0476 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein YPC_0478 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein YPC_0479 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) YPC_0480 ENOG4108RR8 protoporphyrinogen oxidase YPC_0499 ENOG4105PM1 preprotein translocase subunit SecE YPC_0500 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) YPC_0507 ENOG4108RS6 transposase YPC_0514 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) YPC_0519 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) YPC_0520 ENOG4105R2J Conserved Protein YPC_0523 ENOG4108T8B Protein of unknown function (DUF1481) YPC_0524 ENOG4105C12 Phosphoribosylglycinamide synthetase YPC_0533 ENOG4105CMM transposase YPC_0537 ENOG4107ZSV Receptor YPC_0538 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) YPC_0539 ENOG4105CFC Transporter YPC_0550 ENOG4105C1P efflux transporter, rnd family, mfp subunit YPC_0553 ENOG4105BZU Histidine kinase YPC_0554 ENOG4105DQ6 Transposase YPC_0560 ENOG4105CHV Transcription elongation factor NusA YPC_0566 ENOG4105EEI dihydropteroate synthase YPC_0567 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) YPC_0569 ENOG4105HBR Rna-binding protein YPC_0571 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) YPC_0572 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase YPC_0576 ENOG4105QYV Membrane YPC_0579 ENOG4105EAH synthase YPC_0581 ENOG4105HVQ Regulatory factor of maltose metabolism YPC_0586 ENOG4105DFU Cell wall formation (By similarity) YPC_0588 ENOG4105F0N pyrophosphate phospho-hydrolase YPC_0589 ENOG4108ZHD aig2 family YPC_0592 ENOG4105CFU surface antigen YPC_0594 ENOG4105C37 (CBS) domain YPC_0595 ENOG41061GZ Protein of unknown function (DUF1107) YPC_0596 ENOG4108UUE Transcriptional regulator YPC_0597 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase YPC_0598 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic YPC_0600 ENOG4108V1T peptidylprolyl cis-trans isomerase YPC_0601 ENOG4105FHY Opacity-associated protein A YPC_0603 ENOG4108RS6 transposase YPC_0606 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) YPC_0608 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) YPC_0610 ENOG4108MXZ Esterase YPC_0614 ENOG4105WSB biofilm stress and motility protein A YPC_0615 ENOG4105CSU acyl-Coa dehydrogenase YPC_0617 ENOG4105C2N RNA methyltransferase TrmH family group 3 YPC_0619 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) YPC_0623 ENOG4105EPW hflc protein YPC_0624 ENOG4107QJR hflk protein YPC_0625 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) YPC_0629 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase YPC_0630 ENOG4105K8N protein family UPF0079, ATPase YPC_0631 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) YPC_0632 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) YPC_0636 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) YPC_0639 ENOG4105EGS Mechanosensitive ion channel YPC_0645 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) YPC_0646 ENOG4105KPY Small multidrug resistance protein YPC_0648 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein YPC_0649 ENOG4108ZVF (LipO)protein YPC_0655 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPC_0658 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) YPC_0659 ENOG4108RC0 Electron transport protein YPC_0660 ENOG4105BZ8 glutamate synthase YPC_0661 ENOG4108SIC Transcriptional regulator YPC_0677 ENOG4105C0A alcohol dehydrogenase YPC_0679 ENOG4108UUM single-stranded DNA-binding protein YPC_0680 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) YPC_0681 ENOG4105MSB protein, conserved in bacteria YPC_0682 ENOG4105CGF Aromatic amino acid aminotransferase YPC_0683 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) YPC_0684 ENOG4105CDU Replicative dna helicase YPC_0685 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein YPC_0687 ENOG4105P4Z Phage shock protein G YPC_0688 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) YPC_0689 ENOG4105MYN Zinc uptake regulation protein YPC_0691 ENOG41080IJ Diacylglycerol kinase YPC_0702 ENOG4108S1B Periplasmic chaperone protein YPC_0714 ENOG4105DAX Pfam:DUF2983 YPC_0718 ENOG4105D4P Coproporphyrinogen iii oxidase YPC_0719 ENOG41090JE Utilization Protein YPC_0722 ENOG4107F3C Hemin uptake protein YPC_0723 ENOG4107ENK receptor YPC_0724 ENOG4106QJH hemin transport protein YPC_0725 ENOG4107R4I Periplasmic binding protein YPC_0726 ENOG4105EHG Permease protein YPC_0728 ENOG4105C28 cystathionine YPC_0729 ENOG4105C44 Serine transporter YPC_0730 ENOG4105EQ2 LysR family Transcriptional regulator YPC_0731 ENOG4105KSU Redox protein YPC_0732 ENOG41066VF YeeE YedE family protein YPC_0738 ENOG41063Q7 Type III secretion system protein YPC_0741 ENOG4108JIR Flagellum-specific ATP synthase YPC_0754 ENOG4105BZU Histidine kinase YPC_0755 ENOG4105WH1 Two component transcriptional regulator luxr family YPC_0756 ENOG4105CK2 sodium dicarboxylate symporter YPC_0758 ENOG41062QD Membrane YPC_0763 ENOG4105C0W non-ribosomal peptide synthetase YPC_0764 ENOG4105C0W non-ribosomal peptide synthetase YPC_0767 ENOG4105C0W non-ribosomal peptide synthetase YPC_0775 ENOG4105BZ1 (ABC) transporter YPC_0779 ENOG4107EFN gluconate transport system permease 3 YPC_0785 ENOG4105CS6 Rhs element vgr protein YPC_0787 ENOG4105CNA YD repeat protein YPC_0790 ENOG41062WK cellular response to acidity YPC_0792 ENOG4105C8P )-transporter YPC_0793 ENOG4105ETE Transcriptional regulator (LacI family YPC_0795 ENOG4105DQ6 Transposase YPC_0797 ENOG4105CT4 transporter YPC_0799 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) YPC_0800 ENOG4105DUU IucA IucC family protein YPC_0822 ENOG4105CDV Ompa motb domain protein YPC_0824 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPC_0839 ENOG4105CXN decarboxylase YPC_0840 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPC_0841 ENOG4105C2J ABC transporter YPC_0842 ENOG4105CNN ABC, transporter YPC_0847 ENOG4105CEN a g-specific adenine glycosylase YPC_0849 ENOG41090ED Protein with unknown function (DUF469) YPC_0850 ENOG4105CSV Glutaminase YPC_0853 ENOG4105EUK rtx toxin RtxA YPC_0854 ENOG4105CSA Coproporphyrinogen iii oxidase YPC_0855 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) YPC_0857 ENOG4108VIA integral membrane protein YPC_0858 ENOG4105II7 pyrroline-5-carboxylate reductase YPC_0859 ENOG4105DFA alanine racemase domain protein YPC_0860 ENOG4105CZX twitching motility protein YPC_0862 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) YPC_0865 ENOG4105D7Z glutathione synthase YPC_0866 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) YPC_0869 ENOG4105RWS endonuclease I YPC_0873 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) YPC_0876 ENOG4108K0D peptidase, M48 YPC_0877 ENOG4105CV1 Transketolase (EC 2.2.1.1) YPC_0882 ENOG4105D2N Aldolase YPC_0884 ENOG4105D64 Mechanosensitive ion channel YPC_0886 ENOG4105MPN Membrane YPC_0888 ENOG4105E66 phosphoriboisomerase A YPC_0889 ENOG4108JQ1 Dehydrogenase YPC_0891 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase YPC_0895 ENOG4107RAQ aminopeptidase YPC_0896 ENOG4105D0A hydroxylase YPC_0897 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family YPC_0907 ENOG4108UT2 hemolysin iii YPC_0910 ENOG4105Y75 tpr repeat protein YPC_0912 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPC_0913 ENOG4105EB3 Histidine kinase YPC_0914 ENOG4105CT7 inner membrane cred family protein YPC_0915 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) YPC_0916 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPC_0917 ENOG4105T95 Thiol disulfide interChange protein YPC_0918 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) YPC_0922 ENOG4105DFP Integrase YPC_0927 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation YPC_0928 ENOG4105WJ3 XRE family Transcriptional regulator YPC_0948 ENOG4105NTW Transcriptional regulator YPC_0951 ENOG4108UY0 (LipO)protein YPC_0953 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPC_0954 ENOG4105CNN ABC, transporter YPC_0957 ENOG4107FKK extracellular solute-binding protein family 1 YPC_0959 ENOG4105EG2 ABC transporter, permease YPC_0961 ENOG4105C4C beta-galactosidase YPC_0962 ENOG4105CI1 PTS System YPC_0964 ENOG4105ETE Transcriptional regulator (LacI family YPC_0971 ENOG4105ETE Transcriptional regulator (LacI family YPC_0973 ENOG4105D2N Aldolase YPC_0976 ENOG4105ENH Sulfatase YPC_0977 ENOG4105C4X radical SAM domain protein YPC_0981 ENOG4105CE4 GlcNAc 6-P deacetylase YPC_0982 ENOG4108YTN IIa component YPC_0985 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB YPC_0986 ENOG4105E70 isomerase YPC_0987 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of YPC_0988 ENOG4105E98 transcriptional regulator DeoR family YPC_0991 ENOG4105CBG Sulfatase YPC_0992 ENOG4108RS6 transposase YPC_1002 ENOG4107B2H carbonic anhydrase YPC_1006 ENOG4107QHF type ii secretion system protein e YPC_1008 ENOG4105D7Q type ii secretion system YPC_1021 ENOG4105C8Q Methyl-accepting chemotaxis YPC_1024 ENOG4105EJC lysr family transcriptional regulator YPC_1025 ENOG4105F27 Major Facilitator YPC_1026 ENOG4105RQF LysR family Transcriptional regulator YPC_1027 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) YPC_1028 ENOG41060NJ transcriptional regulator YPC_1037 ENOG4105CPC Aldo Keto reductase YPC_1041 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase YPC_1042 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase YPC_1049 ENOG4105DSY exodeoxyribonuclease V, gamma YPC_1050 ENOG4107QXK peptidase YPC_1054 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase YPC_1057 ENOG4105CA3 membrane-bound lytic murein transglycosylase YPC_1058 ENOG4105CUZ uba thif-type nad fad binding protein YPC_1059 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) YPC_1060 ENOG4105C9B Cysteine desulfurase YPC_1063 ENOG4105ETT transcriptional Regulator, LysR family YPC_1064 ENOG4105M08 Membrane YPC_1066 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease YPC_1067 ENOG4105EWT decarboxylase family YPC_1071 ENOG4108RS6 transposase YPC_1072 ENOG4105WP7 tRNA pseudouridine synthase C YPC_1073 ENOG4105DR9 pseudouridine synthase YPC_1074 ENOG4105QDK Flavodoxin YPC_1081 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) YPC_1088 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) YPC_1089 ENOG4105KNE Phosphatidate cytidylyltransferase YPC_1090 ENOG4105DZP Membrane-associated zinc metalloprotease YPC_1092 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) YPC_1096 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) YPC_1098 ENOG4105C0B DNA polymerase III (alpha subunit) YPC_1100 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase YPC_1101 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) YPC_1103 ENOG4105M1T rho-binding antiterminator YPC_1105 ENOG4108VWS Yaeq family YPC_1106 ENOG4108YZN class I peptide chain release factor YPC_1107 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion YPC_1109 ENOG4108R96 Methyltransferase, YaeB family YPC_1110 ENOG4108R8X outer membrane lipoprotein YPC_1111 ENOG4105D01 (LipO)protein YPC_1112 ENOG4108UMI ABC transporter, permease YPC_1114 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase YPC_1121 ENOG4105CV8 reductase YPC_1124 ENOG4105E9H Lytic Murein transglycosylase YPC_1126 ENOG4105D1A Methyltransferase YPC_1128 ENOG4108JDX DNA polymerase iii, epsilon subunit YPC_1130 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease YPC_1136 ENOG4105VUH addiction module killer protein YPC_1149 ENOG4105DFP Integrase YPC_1155 ENOG4108Z1B Cyclase dehydrase YPC_1157 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPC_1158 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) YPC_1159 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) YPC_1161 ENOG4105BZN citrate synthase YPC_1163 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein YPC_1165 ENOG4105E33 succinate dehydrogenase YPC_1166 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 YPC_1167 ENOG4105C7S Dehydrogenase YPC_1169 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha YPC_1170 ENOG4105C4M (Ubiquinol oxidase) subunit I YPC_1171 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii YPC_1173 ENOG4105KJB cyd operon protein YbgE YPC_1174 ENOG4107YD3 Thioesterase YPC_1175 ENOG4105E02 MotA TolQ exbB proton channel YPC_1176 ENOG4105M8F Biopolymer transport protein exbD tolR YPC_1177 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA YPC_1177 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA YPC_1179 ENOG4105KCK Peptidoglycan-associated lipoprotein YPC_1180 ENOG4105UFD tol-pal system protein YbgF YPC_1185 ENOG4106Z1T Nicotinamide Mononucleotide Transporter YPC_1186 ENOG4105PGM cation diffusion facilitator family transporter YPC_1187 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPC_1190 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) YPC_1193 ENOG4105F0Z galactose-1-phosphate uridylyltransferase YPC_1194 ENOG4105CMR udp-glucose 4-epimerase YPC_1197 ENOG4105DKW ABC transporter YPC_1198 ENOG4105F4R Transcriptional regulator mode YPC_1200 ENOG410680R Protein of unknown function (DUF2592) YPC_1201 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein YPC_1202 ENOG4105E0C molybdate abc transporter YPC_1204 ENOG4108K4B hydrolase YPC_1209 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) YPC_1210 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) YPC_1211 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) YPC_1212 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) YPC_1214 ENOG4105VYA Uncharacterized conserved protein (DUF2132) YPC_1215 ENOG4105CHW UPF0052 protein YPC_1216 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) YPC_1218 ENOG4105M00 molybdopterin converting factor, subunit 1 YPC_1219 ENOG4108ZAF Molybdopterin YPC_1220 ENOG4105HFZ Membrane YPC_1223 ENOG4108RS6 transposase YPC_1228 ENOG4105C94 Transporter YPC_1230 ENOG4105CN8 Transcriptional regulator YPC_1232 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) YPC_1237 ENOG4105BZU Histidine kinase YPC_1239 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPC_1244 ENOG4107QWP ABC-2 type transporter YPC_1245 ENOG4107QWP ABC-2 type transporter YPC_1246 ENOG4105CJ1 ABC, transporter YPC_1248 ENOG4107MVR Transcriptional regulator YPC_1249 ENOG4105C1J atp-dependent rna helicase YPC_1250 ENOG4105EQR Transposase IS116 IS110 IS902 YPC_1261 ENOG4105DWF phosphomethylpyrimidine kinase YPC_1264 ENOG4108ZGU inhibitor of vertebrate lysozyme YPC_1267 ENOG4105CFP Peptidase U32 YPC_1268 ENOG4105KWI UPF0339 protein YPC_1269 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPC_1270 ENOG4105EB3 Histidine kinase YPC_1275 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPC_1277 ENOG4108JPW Aminotransferase YPC_1279 ENOG4105F38 ABC transporter, permease YPC_1280 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component YPC_1281 ENOG4105R8A Heat shock protein YPC_1282 ENOG4105CJW magnesium transporter YPC_1284 ENOG4105C9X ppx gppa phosphatase YPC_1285 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) YPC_1293 ENOG4108MK9 spermidine N(1)-acetyltransferase YPC_1294 ENOG4108V3E phosphoribosylglycinamide formyltransferase YPC_1298 ENOG4108RS6 transposase YPC_1300 ENOG4105K89 arsenate reductase YPC_1301 ENOG4105ERG peptidase m48, ste24p YPC_1302 ENOG4105C02 permease YPC_1307 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen YPC_1308 ENOG4105RH4 Glycine cleavage system transcriptional repressor YPC_1310 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPC_1312 ENOG4108RS6 transposase YPC_1314 ENOG4105CGZ zinc metallopeptidase YPC_1320 ENOG4105KUZ arsenate reductase YPC_1323 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC YPC_1324 ENOG4107Z33 ABC transporter, permease YPC_1325 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPC_1326 ENOG4105ENH Sulfatase YPC_1327 ENOG4105C4X radical SAM domain protein YPC_1329 ENOG4105S2T inner membrane protein YbcI YPC_1333 ENOG4105BZS acriflavin resistance protein YPC_1336 ENOG4105WH1 Two component transcriptional regulator luxr family YPC_1337 ENOG4108ZNS ferredoxin-type protein NapF YPC_1338 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase YPC_1341 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) YPC_1342 ENOG4105CUW cytochrome C-TYPE protein YPC_1344 ENOG4105C6K Malic enzyme YPC_1352 ENOG4105H4F exported protein YPC_1353 ENOG4105E7K (LipO)protein YPC_1354 ENOG4105EZR dyp-type peroxidase family protein YPC_1359 ENOG4108R66 Conserved Protein YPC_1361 ENOG4105QEK Transcriptional regulator YPC_1363 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein YPC_1364 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein YPC_1365 ENOG4108I5D sulfate abc transporter YPC_1366 ENOG4105ECW sulfate abc transporter YPC_1367 ENOG4108IJ6 ABC transporter YPC_1368 ENOG4105C6T cysteine synthase YPC_1370 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPC_1371 ENOG41062D9 Histidine kinase YPC_1374 ENOG4105C87 Aminotransferase class I and II YPC_1376 ENOG4107RAQ aminopeptidase YPC_1378 ENOG4105E1V na solute symporter YPC_1381 ENOG4105DJY efflux transporter, rnd family, mfp subunit YPC_1382 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPC_1383 ENOG4105E0F Histidine kinase YPC_1390 ENOG4105C5Y PTS System YPC_1392 ENOG4105KZ7 phosphocarrier protein hpr YPC_1393 ENOG4105C6T cysteine synthase YPC_1394 ENOG4105EXN Sulfate transport protein CysZ YPC_1397 ENOG4105VRT cytoplasmic protein YPC_1403 ENOG4108RS6 transposase YPC_1409 ENOG4105D9N nucleoside YPC_1414 ENOG4105CPC Aldo Keto reductase YPC_1416 ENOG4105C5Q Transcriptional regulator YPC_1419 ENOG41072TH Protein of unknown function (DUF1479) YPC_1420 ENOG4105CHM Aminotransferase YPC_1421 ENOG4108VKM cytochrome b561 YPC_1428 ENOG4108NEM leader-binding protein dmsD YPC_1429 ENOG4107KGK dmso reductase anchor subunit YPC_1430 ENOG4105QAX Iron-sulfur YPC_1431 ENOG4107QY8 reductase YPC_1440 ENOG4105CVE Lytic murein transglycosylase YPC_1452 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPC_1454 ENOG4105GQR Chaperone YPC_1455 ENOG4105CW0 outer membrane usher protein YPC_1457 ENOG4105CW0 outer membrane usher protein YPC_1471 ENOG4105CS6 Rhs element vgr protein YPC_1477 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA YPC_1480 ENOG4108V0P LemA family YPC_1486 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) YPC_1487 ENOG41060IM Heme exporter protein YPC_1488 ENOG4105X3C heme exporter protein YPC_1491 ENOG4107QX9 Thiol disulfide interChange protein YPC_1494 ENOG410903C (LipO)protein YPC_1495 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation YPC_1496 ENOG4105KZW UPF0381 protein YPC_1499 ENOG4108BY2 phosphohistidine phosphatase YPC_1501 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) YPC_1504 ENOG4105EJ9 Membrane YPC_1506 ENOG4108BPE -transporting atpase YPC_1507 ENOG4105MH2 YfcL protein YPC_1509 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPC_1514 ENOG4106WZ1 flagella biosynthesis regulator YPC_1515 ENOG410631K Membrane YPC_1518 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) YPC_1520 ENOG4105DQR SNARE associated Golgi YPC_1522 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase YPC_1523 ENOG4108S3P Sporulation domain protein YPC_1524 ENOG4105E96 Colicin v production protein YPC_1525 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase YPC_1526 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YPC_1529 ENOG4105E89 ABC transporter YPC_1530 ENOG4105DSP amino acid AbC transporter YPC_1531 ENOG4106YG3 ABC transporter YPC_1532 ENOG4108JEH abc transporter atp-binding protein YPC_1533 ENOG4105ECP epimerase YPC_1535 ENOG4108RE9 Phosphodiesterase YPC_1537 ENOG4105PTV Nudix Hydrolase YPC_1538 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC YPC_1543 ENOG4107P2S Transcriptional regulator YPC_1545 ENOG4105C6K Malic enzyme YPC_1551 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 YPC_1552 ENOG4107QWE )-transporter YPC_1556 ENOG4105CHM Aminotransferase YPC_1558 ENOG4107NQ8 LysR family Transcriptional regulator YPC_1561 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) YPC_1563 ENOG4105GKE subunit e YPC_1564 ENOG4107QIZ NADH dehydrogenase YPC_1565 ENOG4108IEH NADH dehydrogenase subunit g YPC_1568 ENOG4107UFS subunit j YPC_1570 ENOG4105D65 subunit l YPC_1571 ENOG4105C8S subunit m YPC_1574 ENOG4108R66 Conserved Protein YPC_1575 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family YPC_1576 ENOG4105CHR reductase YPC_1579 ENOG4105F32 YngK protein YPC_1580 ENOG4105K2J Transcriptional regulator YPC_1582 ENOG4105C5I Dehydrogenase YPC_1586 ENOG4105C01 Dihydroxy-acid dehydratase YPC_1590 ENOG4105TNS Conserved Protein YPC_1593 ENOG4105E4F Isochorismate synthase YPC_1596 ENOG4108IPT Naphthoate synthase YPC_1598 ENOG4105CEY Amp-dependent synthetase and ligase YPC_1599 ENOG4108MTB glycosyl transferase family YPC_1602 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction YPC_1608 ENOG4107SDU Methyl-accepting chemotaxis YPC_1609 ENOG4105CDA abc transporter atp-binding protein YPC_1610 ENOG4105E5Q amino acid AbC transporter YPC_1611 ENOG4107R0W ABC transporter YPC_1619 ENOG4108T1M outer membrane protein x YPC_1623 ENOG4105CPQ Dehydrogenase YPC_1624 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPC_1625 ENOG4105C2J ABC transporter YPC_1626 ENOG4105CNN ABC, transporter YPC_1627 ENOG4105FKQ transcriptional regulator YPC_1628 ENOG4105EJC lysr family transcriptional regulator YPC_1629 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) YPC_1631 ENOG4105C94 Transporter YPC_1634 ENOG4105E3J oxidoreductase YPC_1635 ENOG4105D5K Hemolysin activator protein YPC_1636 ENOG4105CKT filamentous hemagglutinin YPC_1637 ENOG4105CKT filamentous hemagglutinin YPC_1640 ENOG4105CKT filamentous hemagglutinin YPC_1645 ENOG4105CKT filamentous hemagglutinin YPC_1646 ENOG4105CKT filamentous hemagglutinin YPC_1648 ENOG4108IJ9 (ABC) transporter YPC_1650 ENOG4105ETE Transcriptional regulator (LacI family YPC_1653 ENOG4105DRS transport system, permease YPC_1654 ENOG4105HY2 Glycosidase related protein YPC_1658 ENOG4105CUY Mechanosensitive ion channel YPC_1659 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) YPC_1660 ENOG4107IIZ CRISPR-associated helicase, Cas3 YPC_1661 ENOG4105ENG CRISPR-associated protein, Csy1 family YPC_1662 ENOG4105DZX CRISPR-associated protein, Csy2 family YPC_1663 ENOG4105M6W Crispr-associated protein, Csy3 family YPC_1664 ENOG4108Y1S CRISPR-associated protein, Csy4 family YPC_1665 ENOG4105CPC Aldo Keto reductase YPC_1668 ENOG4105C54 Major Facilitator superfamily YPC_1669 ENOG4105ETT transcriptional Regulator, LysR family YPC_1670 ENOG4105VJY transcriptional regulator YPC_1671 ENOG4107YC3 synthase YPC_1678 ENOG4105DSF transport protein YPC_1683 ENOG4105PVA Biofilm formation regulatory protein BssS YPC_1686 ENOG41067V3 Antibiotic biosynthesis monooxygenase YPC_1688 ENOG4107QQB Ribonuclease E YPC_1689 ENOG4105EI2 Pseudouridine synthase YPC_1691 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein YPC_1692 ENOG4105VGS 50s ribosomal protein l32 YPC_1695 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase YPC_1696 ENOG4105CHR reductase YPC_1698 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPC_1701 ENOG4105YAZ 4-amino-4-deoxychorismate lyase YPC_1703 ENOG4105HHA aminodeoxychorismate lyase YPC_1705 ENOG4107QRG dna polymerase iii YPC_1706 ENOG4105F8V Hydrolase, tatD family YPC_1707 ENOG4105CI1 PTS System YPC_1710 ENOG4105F9E Shikimate 5-dehydrogenase YPC_1711 ENOG4105K59 histidine triad (HIT) protein YPC_1712 ENOG41090DQ Lipoprotein YPC_1715 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) YPC_1717 ENOG4105CEP NADH dehydrogenase YPC_1723 ENOG4107MBR 17 kDa surface antigen YPC_1724 ENOG4108JA2 transcriptioN-repair coupling factor YPC_1726 ENOG4105D60 lipoprotein releasing system transmembrane protein YPC_1728 ENOG4105D60 lipoprotein releasing system transmembrane protein YPC_1732 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) YPC_1734 ENOG4105EZE Cupin 4 family protein YPC_1736 ENOG4105XJC Two component transcriptional regulator (Winged helix family YPC_1738 ENOG4107QTF adenylosuccinate lyase YPC_1742 ENOG4108R99 pseudouridine synthase YPC_1743 ENOG4108HMX isocitrate dehydrogenase (NADP) YPC_1744 ENOG4106NDP Transcriptional regulator YPC_1746 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor YPC_1747 ENOG4105ECR NmrA family YPC_1748 ENOG4105KVH Transcriptional regulator YPC_1752 ENOG4105D6F Phosphatase YPC_1753 ENOG4105D6F Phosphatase YPC_1755 ENOG41061EV selenium-binding protein YdfZ YPC_1757 ENOG4108XM1 transcriptional regulator AsnC family YPC_1759 ENOG4105GSJ Inner membrane protein ylaC YPC_1762 ENOG4105VEQ Cold shock protein YPC_1766 ENOG4105KT7 mgtC SapB transporter YPC_1767 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic YPC_1768 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic YPC_1771 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region YPC_1772 ENOG4107RD7 Flagellar Motor Protein, MotA YPC_1773 ENOG4105ER2 Ompa motb domain protein YPC_1774 ENOG4105CBS Chea signal transduction histidine kinase YPC_1775 ENOG4108V3W Chemotaxis protein, CheW YPC_1776 ENOG4105R9B Major Facilitator YPC_1777 ENOG4105KME endoribonuclease L-psp YPC_1779 ENOG4105WWK YheO domain protein YPC_1783 ENOG4105C8Q Methyl-accepting chemotaxis YPC_1784 ENOG4105C8Q Methyl-accepting chemotaxis YPC_1785 ENOG4105BZU Histidine kinase YPC_1787 ENOG4108VYJ response regulator receiver protein YPC_1788 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) YPC_1791 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPC_1792 ENOG4105EUR Domain-Containing protein YPC_1795 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) YPC_1802 ENOG4108EKI Dehydrogenase YPC_1803 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein YPC_1804 ENOG4107QSI ABC, transporter YPC_1806 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPC_1807 ENOG4105C3U ABC transporter YPC_1808 ENOG4108JQ7 (ABC) transporter YPC_1814 ENOG4108T1M outer membrane protein x YPC_1818 ENOG4105K9H YciI-like protein YPC_1819 ENOG410822N TonB family YPC_1821 ENOG4105NAU thioesterase Superfamily protein YPC_1828 ENOG4105EIF outer membrane protein W YPC_1833 ENOG4105DK0 Indole-3-glycerol phosphate synthase YPC_1835 ENOG4105DDQ anthranilate synthase YPC_1838 ENOG4105DB7 PHP domain protein YPC_1840 ENOG4107RTD sua5 ycio yrdc ywlc family protein YPC_1841 ENOG4105FE9 pseudouridine synthase YPC_1842 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase YPC_1843 ENOG4105UBK short-chain dehydrogenase reductase YPC_1844 ENOG4105ERU peptidase YPC_1846 ENOG4105RKX Protein of unknown function (DUF2498) YPC_1848 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) YPC_1849 ENOG4107R11 Transcriptional regulator YPC_1851 ENOG4107QM5 aconitate hydratase YPC_1852 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) YPC_1853 ENOG4105EYK Phosphatidylglycerophosphatase B YPC_1854 ENOG4105Q4A inner membrane protein yciS YPC_1855 ENOG4105CFV Tetratricopeptide repeat protein YPC_1858 ENOG4108ZJT translation initiation factor, Sui1 YPC_1859 ENOG41061RM osmotically inducible lipoprotein YPC_1860 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase YPC_1862 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) YPC_1863 ENOG4105VCD cytoplasmic protein YPC_1864 ENOG4105D22 carbon starvation protein YPC_1866 ENOG4105CSP Major Facilitator Superfamily YPC_1867 ENOG4105EXW epimerase dehydratase YPC_1868 ENOG4105CSM endonuclease III YPC_1871 ENOG4105D6A Electron transport complex YPC_1872 ENOG4105UEI Transcriptional Regulator AraC Family YPC_1877 ENOG4105M9B inner membrane protein ydgK YPC_1879 ENOG4108JJA ABC, transporter YPC_1880 ENOG4108JJA ABC, transporter YPC_1882 ENOG4105C42 Type I secretion membrane fusion protein (HlyD YPC_1883 ENOG4108JJA ABC, transporter YPC_1886 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator YPC_1888 ENOG4105CNN ABC, transporter YPC_1890 ENOG4105D9R oxidoreductase YPC_1891 ENOG4105DHU Bile acid YPC_1894 ENOG4106J39 exported protein YPC_1895 ENOG4105EIP mannose-6-phosphate isomerase YPC_1896 ENOG4105C9Q fumarate hydratase class II YPC_1897 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) YPC_1898 ENOG4105D94 Major Facilitator Superfamily YPC_1899 ENOG4106NZI LysR family Transcriptional regulator YPC_1900 ENOG4105DAG ROK family YPC_1902 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) YPC_1903 ENOG4105CMQ Chloride channel YPC_1904 ENOG41060NJ transcriptional regulator YPC_1907 ENOG4107UWC ABC, transporter YPC_1908 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component YPC_1909 ENOG4105D7T ABC transporter YPC_1910 ENOG4105FYV Amp nucleosidase YPC_1919 ENOG4105M71 acetolactate synthase 1 regulatory subunit YPC_1920 ENOG4105PAD Hydrolase YPC_1923 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) YPC_1924 ENOG4105DS0 Transcriptional regulator, Crp Fnr family YPC_1925 ENOG4105Q9Y Universal stress protein YPC_1928 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) YPC_1929 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) YPC_1931 ENOG4105C5D exported protein YPC_1932 ENOG4105D5Q Arginine ornithine antiporter YPC_1934 ENOG4107EXC regulatoR YPC_1935 ENOG4105JJR Histidine kinase YPC_1936 ENOG4105CTD carboxy-peptidase YPC_1943 ENOG4105DS1 cytochrome b561 YPC_1948 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap YPC_1951 ENOG4105CQ7 ATP-dependent helicase YPC_1953 ENOG4105DKT Transcriptional regulator YPC_1954 ENOG4105DEI Mannitol dehydrogenase YPC_1955 ENOG4105WXT Conserved Protein YPC_1956 ENOG410689M (LipO)protein YPC_1957 ENOG4107H52 Dicarboxylate transport YPC_1958 ENOG4105C5I Dehydrogenase YPC_1959 ENOG41090X5 Heat shock protein hslJ YPC_1961 ENOG4105KT7 mgtC SapB transporter YPC_1963 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) YPC_1969 ENOG4107QSI ABC, transporter YPC_1970 ENOG4105KXI murein peptide amidase A YPC_1971 ENOG4107S8C mandelate racemase muconate lactonizing YPC_1972 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) YPC_1974 ENOG4108RS6 transposase YPC_1979 ENOG4105CM6 amino acid regulated cytosolic protein YPC_1981 ENOG4105FM1 phage shock protein C YPC_1982 ENOG4105YYT phage shock protein B YPC_1983 ENOG41087YS Phage shock protein A YPC_1984 ENOG4105E51 psp operon transcriptional activator YPC_1987 ENOG4108HIY periplasmic YPC_1988 ENOG4108I5W peptide transport system, permease protein YPC_1989 ENOG4108EU3 peptide transport system, permease YPC_1992 ENOG4105Q4T oxidoreductase YPC_1994 ENOG4105DUX Transporter YPC_1995 ENOG41069YE inner membrane protein yohC YPC_1996 ENOG4108ZR5 Conserved Protein YPC_1997 ENOG4108K3A Glutathione S-transferase YPC_2001 ENOG410642K Lysozyme inhibitor YPC_2004 ENOG4108XTF Outer Membrane Lipoprotein YPC_2006 ENOG4105DIJ Phosphoethanolamine transferase YPC_2007 ENOG4108WUH Transcriptional regulator, TetR family YPC_2009 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPC_2011 ENOG4108UYE Lactoylglutathione lyase YPC_2012 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) YPC_2014 ENOG4105M2J Glutaredoxin YPC_2016 ENOG4105K4H Nlp p60 protein YPC_2017 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) YPC_2018 ENOG4105F52 Transcriptional regulator YPC_2019 ENOG4105CZQ inner membrane transport protein YdhC YPC_2020 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase YPC_2021 ENOG4108R6K riboflavin synthase, subunit alpha YPC_2025 ENOG4105CA9 Pyruvate kinase YPC_2026 ENOG4105KMX major outer membrane lipoprotein YPC_2032 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein YPC_2035 ENOG4105JRK feS assembly protein SufD YPC_2036 ENOG4105C3K feS assembly ATPase SufC YPC_2037 ENOG4105DIW FeS assembly protein SUFB YPC_2038 ENOG4108Z4V iron-sulfur cluster assembly YPC_2039 ENOG4105KA0 thioesterase Superfamily protein YPC_2040 ENOG4105CQB FAD linked oxidase domain protein YPC_2041 ENOG4105IPI Membrane YPC_2043 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) YPC_2045 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPC_2049 ENOG4108QBX (LipO)protein YPC_2058 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) YPC_2059 ENOG4108V06 Glutathione peroxidase YPC_2062 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) YPC_2063 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) YPC_2064 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) YPC_2073 ENOG41087WU YPC_2080 ENOG4105DSE periplasmic solute binding protein YPC_2081 ENOG4105DIK (ABC) transporter YPC_2085 ENOG4105FGM Fructosamine kinase YPC_2086 ENOG4107PN8 YfeABCD locus regulator YPC_2087 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 YPC_2090 ENOG4105M5J Cupin 2, conserved barrel domain protein YPC_2092 ENOG4105CHR reductase YPC_2093 ENOG41061NF Pectate lyase YPC_2097 ENOG4105WEM extracellular solute-binding protein YPC_2098 ENOG4108PU9 oligogalacturonate-specific porin YPC_2099 ENOG4107K5X Membrane-bound metal-dependent hydrolase YPC_2100 ENOG4108ETY sodium dicarboxylate symporter YPC_2102 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPC_2104 ENOG4105CAZ oligogalacturonide lyase YPC_2105 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPC_2106 ENOG4108VEV chaperone YPC_2109 ENOG4108VEV chaperone YPC_2110 ENOG4105H8W Fimbrial protein YPC_2112 ENOG4105CN1 protease YPC_2115 ENOG4108ZGC gaf domain protein YPC_2116 ENOG4105H2K paraquat-inducible protein a YPC_2122 ENOG4105GQR Chaperone YPC_2126 ENOG4105WT8 Protein of unknown function (DUF1480) YPC_2131 ENOG4107104 thymidine kinase YPC_2136 ENOG4105I93 response regulator YPC_2138 ENOG4105CIY formyltetrahydrofolate deformylase YPC_2141 ENOG4105SKE transcriptional Regulator LysR family YPC_2143 ENOG4105CGK Exodeoxyribonuclease III YPC_2144 ENOG4105M6F mutator MutT protein YPC_2145 ENOG4105MTM Protein of unknown function (DUF1496) YPC_2147 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) YPC_2148 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) YPC_2150 ENOG41069NU Nitroreductase YPC_2153 ENOG4105HDK L-asparaginase YPC_2154 ENOG4108RWI nicotinamidase YPC_2155 ENOG4105VUT cytoplasmic protein YPC_2158 ENOG4105DSB aldose 1-epimerase YPC_2159 ENOG4105GNX MltA-interacting MipA family protein YPC_2160 ENOG4105CYN Serine protein kinase YPC_2163 ENOG4105HEI LysR family (Transcriptional regulator YPC_2164 ENOG4105EUB pirin domain protein YPC_2166 ENOG4105CNH Multidrug resistance protein MdtL YPC_2168 ENOG4105ED1 spovr family YPC_2174 ENOG4105C3J Cysteine desulfurase YPC_2178 ENOG4105UZW Tail fiber assembly protein YPC_2220 ENOG4105HRS Antitermination protein YPC_2222 ENOG4105NY2 NinB protein YPC_2227 ENOG4107R08 Integrase YPC_2229 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase YPC_2230 ENOG4105CVE Lytic murein transglycosylase YPC_2235 ENOG4107QMS site-determining protein YPC_2236 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) YPC_2237 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) YPC_2238 ENOG4105CEY Amp-dependent synthetase and ligase YPC_2240 ENOG4105Y4Z Outer Membrane Lipoprotein YPC_2241 ENOG41072GX Peptidase M22 Glycoprotease YPC_2243 ENOG4105DVT helicase YPC_2244 ENOG4105M4H endoribonuclease L-psp YPC_2247 ENOG4108UHU Aldolase YPC_2248 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase YPC_2249 ENOG4106KNT transcriptional regulator YPC_2250 ENOG4105CA9 Pyruvate kinase YPC_2252 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase YPC_2253 ENOG4105DR5 peptidase YPC_2254 ENOG4105NXV High-affinity zinc uptake system protein YPC_2256 ENOG4105FAV ABC, transporter YPC_2261 ENOG4108TIT dATP pyrophosphohydrolase YPC_2263 ENOG41081XQ Conserved Protein YPC_2264 ENOG4105WJG Glutathione YPC_2269 ENOG4106ZCM YecM protein YPC_2275 ENOG4105CJR Integral membrane protein (MviN YPC_2276 ENOG4105EP9 oxidoreductase YPC_2278 ENOG4105D9U N-acetyltransferase YPC_2281 ENOG4105F3T (LipO)protein YPC_2285 ENOG4107XHZ cytoplasmic chaperone TorD family protein YPC_2288 ENOG4105E2R ROK family YPC_2289 ENOG4108QXE glycerophosphoryl diester phosphodiesterase YPC_2291 ENOG4105F38 ABC transporter, permease YPC_2292 ENOG4105EG2 ABC transporter, permease YPC_2296 ENOG4105CHH sulfate transporter YPC_2299 ENOG41063JG Transcriptional regulator YPC_2300 ENOG4108YY7 Invasion gene expression up-regulator SirB YPC_2301 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) YPC_2306 ENOG4105C5T Phosphoribosyl pyrophosphate synthase YPC_2308 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria YPC_2311 ENOG4105C3G gtp-binding protein YPC_2319 ENOG4105ENX hydrolase YPC_2321 ENOG4105GR3 Histidine kinase YPC_2330 ENOG4108WF3 methyltransferase YPC_2344 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase YPC_2348 ENOG41090B9 response to stress YPC_2349 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) YPC_2350 ENOG4105CZE histidine utilization repressor YPC_2353 ENOG4105FCK Membrane YPC_2360 ENOG4108IJ9 (ABC) transporter YPC_2364 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) YPC_2366 ENOG4105FDP GntR family transcriptional regulator YPC_2386 ENOG4108WC9 type VI secretion system effector, hcp1 family YPC_2397 ENOG4105WH1 Two component transcriptional regulator luxr family YPC_2398 ENOG4105XVG cytoplasmic protein YPC_2400 ENOG4105RA2 Membrane YPC_2402 ENOG4108T1M outer membrane protein x YPC_2404 ENOG4105C85 amino acid YPC_2407 ENOG4105DBE peroxidase YPC_2410 ENOG4105CK7 Sodium proline symporter YPC_2412 ENOG4105C26 Dehydrogenase YPC_2416 ENOG4105CDA abc transporter atp-binding protein YPC_2417 ENOG4105E5Q amino acid AbC transporter YPC_2418 ENOG4105EAB amino acid AbC transporter YPC_2419 ENOG4105K6H D-cysteine desulfhydrase YPC_2420 ENOG4108M9K flagella biosynthesis protein FliZ YPC_2422 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPC_2424 ENOG4105I03 Flagellin YPC_2425 ENOG4105DTS flagellar hook-associated YPC_2426 ENOG4105MQ3 flagellar protein FliS YPC_2429 ENOG4108T5G Adenylate YPC_2431 ENOG4105DHT Metal Dependent Phosphohydrolase YPC_2435 ENOG4105VQ0 flagellar hook-basal body complex protein fliE YPC_2436 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) YPC_2437 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) YPC_2438 ENOG41090PJ Flagellar assembly protein YPC_2439 ENOG4108JIR Flagellum-specific ATP synthase YPC_2440 ENOG4105GSA Flagellar export protein flij YPC_2441 ENOG4105WF4 Flagellar hook-length control protein YPC_2443 ENOG4107ZI8 flagellar basal body-associated protein flil YPC_2444 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) YPC_2445 ENOG4105DD5 Flagellar motor switch protein YPC_2447 ENOG4105CN7 Flagellar biosynthetic protein FliP YPC_2448 ENOG4105VS8 Flagellar biosynthetic protein fliq YPC_2449 ENOG4105D19 Role in flagellar biosynthesis (By similarity) YPC_2452 ENOG4108MGF sugar kinase YPC_2453 ENOG4105CNN ABC, transporter YPC_2454 ENOG4107R9N ABC transporter YPC_2455 ENOG4105C2J ABC transporter YPC_2458 ENOG4105CNN ABC, transporter YPC_2460 ENOG4105DKT Transcriptional regulator YPC_2461 ENOG4105DTJ flagellar hook-associated protein YPC_2462 ENOG4105E1Q flagellar hook-associated protein YPC_2467 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj YPC_2470 ENOG4105CGA flagellar basal-body rod protein FlgG YPC_2471 ENOG4108KPB Flagellar basal-body rod protein FlgF YPC_2472 ENOG4105BZE flagellar hook protein, FlgE YPC_2473 ENOG4105W00 Flagellar hook capping protein YPC_2474 ENOG4108ZC9 flagellar basal-body rod protein flgc YPC_2475 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) YPC_2476 ENOG4105CKS Flagella basal body P-ring formation protein flgA YPC_2477 ENOG4105M9M anti-sigma28 factor FlgM YPC_2478 ENOG4105QVD Flagella synthesis protein FlgN YPC_2483 ENOG4105W13 flagellar protein YPC_2486 ENOG4105D00 flagellar biosynthetic protein flhB YPC_2487 ENOG4105D00 flagellar biosynthetic protein flhB YPC_2492 ENOG4105NKT exported protein YPC_2494 ENOG4105FXM Copper resistance protein YPC_2495 ENOG41090A1 ferritin YPC_2497 ENOG4105MPK DNA polymerase III subunit theta YPC_2501 ENOG4105CUG Oligopeptidase b YPC_2504 ENOG4105X2V dna damage-inducible protein YPC_2505 ENOG4105C1J atp-dependent rna helicase YPC_2508 ENOG4105CRQ synthase (Component I) YPC_2510 ENOG4105EJQ L-serine dehydratase YPC_2511 ENOG4107UWN reductase YPC_2512 ENOG4105EFA 4-hydroxyphenylacetate YPC_2518 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase YPC_2519 ENOG4105C26 Dehydrogenase YPC_2522 ENOG4108V8F Transcriptional regulator, MarR family YPC_2523 ENOG4105EE5 Membrane protein terC YPC_2524 ENOG4108EQA pts system YPC_2525 ENOG4105ETZ PTS System YPC_2526 ENOG4105F3R pts system mannose fructose sorbose family iid YPC_2531 ENOG4105BZU Histidine kinase YPC_2533 ENOG4105DHI Methyltransferase YPC_2534 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase YPC_2535 ENOG4105VEQ Cold shock protein YPC_2536 ENOG410610J Protein of unknown function (DUF2627) YPC_2538 ENOG4105C85 amino acid YPC_2541 ENOG41064PC YPC_2542 ENOG4105TIK YPC_2543 ENOG4105N4N Protein of unknown function (DUF2766) YPC_2546 ENOG4105BZ1 (ABC) transporter YPC_2557 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) YPC_2561 ENOG4108TSE Transferase YPC_2562 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit YPC_2565 ENOG4105CG6 trap dicarboxylate transporter dctm subunit YPC_2566 ENOG4108KX4 response regulator YPC_2570 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme YPC_2576 ENOG4105UQX Mate efflux family protein YPC_2580 ENOG4105DIA mandelate racemase muconate lactonizing YPC_2582 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr YPC_2583 ENOG4105KIR Thiol-disulfide oxidoreductase dcc YPC_2584 ENOG4105CSP Major Facilitator Superfamily YPC_2586 ENOG4105TNG K13735 adhesin invasin YPC_2591 ENOG4105CJB Exodeoxyribonuclease I YPC_2592 ENOG4105CUB amino acid YPC_2594 ENOG4107SCQ Iron-containing alcohol dehydrogenase YPC_2595 ENOG4105C2J ABC transporter YPC_2596 ENOG4105C2J ABC transporter YPC_2597 ENOG4105CNN ABC, transporter YPC_2599 ENOG4108535 NAD dependent epimerase/dehydratase family YPC_2602 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) YPC_2604 ENOG4105ECC imidazole-glycerol-phosphate dehydratase YPC_2605 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) YPC_2608 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase YPC_2609 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) YPC_2610 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase YPC_2611 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase YPC_2613 ENOG4105DUU IucA IucC family protein YPC_2614 ENOG4105CNM Receptor YPC_2615 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) YPC_2618 ENOG4105TVJ transport system, permease YPC_2619 ENOG4105E0A ABC, transporter YPC_2623 ENOG4105DY8 decarboxylase YPC_2624 ENOG4108819 ferric iron reductase YPC_2625 ENOG4105EE5 Membrane protein terC YPC_2626 ENOG4108GAE asmA family YPC_2629 ENOG4105D1F ATP-binding protein YPC_2631 ENOG4108RS6 transposase YPC_2637 ENOG4105E5W Transporter YPC_2639 ENOG41067MG lrgb family YPC_2643 ENOG4107GZ4 SanA protein YPC_2644 ENOG4108HWV )-transporter YPC_2648 ENOG4105DHF Membrane YPC_2650 ENOG4105CBP Major Facilitator YPC_2651 ENOG4105EGI Transcriptional regulator YPC_2656 ENOG4105ENT Efflux transporter rnd family, mfp subunit YPC_2657 ENOG4105C19 ABC transporter YPC_2659 ENOG4105CVM Molybdenum cofactor synthesis domain protein YPC_2660 ENOG4105D06 uba thif-type nad fad binding protein YPC_2663 ENOG4105C5H ABC transporter YPC_2686 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPC_2688 ENOG4105CDV Ompa motb domain protein YPC_2693 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase YPC_2694 ENOG41062T2 Acyl carrier protein YPC_2697 ENOG4105CHR reductase YPC_2700 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase YPC_2701 ENOG4105CHR reductase YPC_2702 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPC_2703 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) YPC_2710 ENOG4108BUD transposase YPC_2712 ENOG4108Z0T Part of a sulfur-relay system (By similarity) YPC_2717 ENOG4105K4P CoA-binding domain protein YPC_2719 ENOG4108Q67 UPF0319 protein YPC_2721 ENOG41088T4 Helicase IV YPC_2722 ENOG410901E Membrane YPC_2723 ENOG4105EM2 membrane YPC_2724 ENOG4108RZ1 DNA transformation protein YPC_2726 ENOG4105UYK outer membrane protein a YPC_2728 ENOG4108RS6 transposase YPC_2730 ENOG4105DAN ATP-dependent protease YPC_2732 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPC_2735 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPC_2736 ENOG4108RS6 transposase YPC_2738 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) YPC_2740 ENOG4108Q2G (LipO)protein YPC_2741 ENOG4105DY2 Paraquat-inducible protein b YPC_2742 ENOG4105F1S paraquat-inducible protein a YPC_2743 ENOG4105C5H ABC transporter YPC_2745 ENOG4105QVC MOSC domain-containing protein YPC_2746 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) YPC_2749 ENOG4105CD8 aminopeptidase N YPC_2756 ENOG4105CGF Aromatic amino acid aminotransferase YPC_2758 ENOG4105C5X domain protein YPC_2759 ENOG4105EAQ (twin-arginine translocation) pathway signal YPC_2760 ENOG4105DIT ErfK YbiS YcfS YnhG family protein YPC_2764 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) YPC_2765 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) YPC_2766 ENOG4106371 Methyltransferase YPC_2768 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups YPC_2770 ENOG4105W49 UPF0434 protein YPC_2772 ENOG4105VEQ Cold shock protein YPC_2773 ENOG4105E32 cytoplasmic protein YPC_2776 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 YPC_2779 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) YPC_2785 ENOG4105HDK L-asparaginase YPC_2786 ENOG4105DDY UPF0142 protein ycaO YPC_2788 ENOG4105TMB Formate nitrite transporter YPC_2789 ENOG4105C6N Formate acetyltransferase YPC_2791 ENOG4105F1A Pyruvate formate-lyase YPC_2792 ENOG4108ISG Major Facilitator YPC_2795 ENOG4108ISG Major Facilitator YPC_2797 ENOG4105D1H recombination factor protein RarA YPC_2799 ENOG4105CNU cell division protein FtsK YPC_2801 ENOG4105EW9 transcriptional regulator AsnC family YPC_2802 ENOG4105C3M thioredoxin reductase YPC_2804 ENOG4108JJ9 ABC, transporter YPC_2805 ENOG4108JJ8 (ABC) transporter YPC_2809 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) YPC_2816 ENOG4105VEQ Cold shock protein YPC_2818 ENOG4105DJY efflux transporter, rnd family, mfp subunit YPC_2821 ENOG4108MJ5 VirK protein YPC_2822 ENOG4105CPB ATP-dependent endonuclease of the OLD family YPC_2823 ENOG4105DWU Membrane YPC_2825 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) YPC_2826 ENOG4105C7K acetolactate synthase YPC_2828 ENOG4105C5W Aldolase YPC_2829 ENOG4105CGD Nad-dependent epimerase dehydratase YPC_2830 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase YPC_2831 ENOG41064MM (LipO)protein YPC_2833 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) YPC_2834 ENOG4105E5Z arginine transporter ATP-binding subunit YPC_2835 ENOG4106PMH Extracellular solute-binding protein family 3 YPC_2836 ENOG4105GBT ABC transporter YPC_2837 ENOG4105DMR ABC, transporter YPC_2839 ENOG4108I0N Transporter, RarD family, DMT superfamily protein YPC_2840 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) YPC_2841 ENOG410642S Nicotianamine synthase protein YPC_2842 ENOG4105E0A ABC, transporter YPC_2849 ENOG4106TNF Periplasmic binding protein YPC_2851 ENOG4105RBQ inner membrane protein ybjO YPC_2852 ENOG4105D38 putrescine abc transporter YPC_2853 ENOG4105F38 ABC transporter, permease YPC_2854 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPC_2855 ENOG4107RUE extracellular solute-binding protein family 1 YPC_2856 ENOG4108RMJ sensory transduction regulator YPC_2857 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress YPC_2858 ENOG41090BQ Glutaredoxin YPC_2859 ENOG4105D0C transport protein YPC_2862 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase YPC_2863 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPC_2864 ENOG4107FB0 transcriptional regulator DeoR family YPC_2867 ENOG4105C44 Serine transporter YPC_2868 ENOG4105C44 Serine transporter YPC_2870 ENOG4105DZ1 carboxypeptidase YPC_2871 ENOG4108UMI ABC transporter, permease YPC_2873 ENOG4105D01 (LipO)protein YPC_2877 ENOG4108TGY Glutathione S-transferase YPC_2878 ENOG4105D05 Receptor YPC_2880 ENOG4105EHG Permease protein YPC_2884 ENOG4105DUM transcriptional regulator, lysR family YPC_2885 ENOG4105HMI Membrane YPC_2887 ENOG4108D1K outer membrane usher protein YPC_2888 ENOG4108UIF Chaperone YPC_2891 ENOG4108SGD regulatory protein YPC_2892 ENOG4105DM4 PTS System YPC_2893 ENOG4105DE4 1-phosphofructokinase YPC_2894 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein YPC_2897 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane YPC_2898 ENOG4105C2J ABC transporter YPC_2899 ENOG4105C2J ABC transporter YPC_2902 ENOG4105E66 phosphoriboisomerase A YPC_2904 ENOG4105C26 Dehydrogenase YPC_2907 ENOG4105CHR reductase YPC_2908 ENOG4105KRS Proteinase inhibitor YPC_2911 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) YPC_2913 ENOG4105DEI Mannitol dehydrogenase YPC_2914 ENOG4107YCY Transcriptional regulator YPC_2917 ENOG4105CKI cobalamin synthesis protein YPC_2918 ENOG41076MN Phosphoesterase, PA-phosphatase related YPC_2920 ENOG4107TT5 NLP P60 protein YPC_2924 ENOG4105CXC rtn protein YPC_2925 ENOG4105E43 Extracellular solute-binding protein, family 5 YPC_2926 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component YPC_2927 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component YPC_2928 ENOG4108JQ5 ABC transporter YPC_2929 ENOG4108JQ5 ABC transporter YPC_2930 ENOG4105HG6 YPC_2932 ENOG4105C2C drug resistance transporter, Bcr CflA YPC_2933 ENOG4105I08 Pseudouridine synthase YPC_2934 ENOG4105CFI type iii restriction protein res subunit YPC_2936 ENOG4108RS6 transposase YPC_2939 ENOG4105PAN UPF0352 protein YPC_2940 ENOG4105E68 Sulfatase YPC_2942 ENOG4105GMB type VI secretion system effector, hcp1 family YPC_2947 ENOG4105CS2 ec 3.2.1.21 YPC_2948 ENOG4108Q3X Transcriptional regulator YPC_2952 ENOG4108T86 baseplate J family protein YPC_2962 ENOG4105TKZ Tail Sheath YPC_2966 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) YPC_2967 ENOG4105MVE transcriptional regulator YPC_2969 ENOG4105G63 Type III effector Hrp-dependent YPC_2970 ENOG4105HRS Antitermination protein YPC_2973 ENOG4105Y50 Virulence Protein YPC_2975 ENOG4105C8Q Methyl-accepting chemotaxis YPC_2977 ENOG4105CT4 transporter YPC_2979 ENOG4107R6D beta-lactam binding protein AmpH YPC_2985 ENOG4105FCK Membrane YPC_2987 ENOG4106UW1 Major Facilitator superfamily YPC_2988 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC YPC_2989 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC YPC_2990 ENOG41068CG regulatoR YPC_2991 ENOG4105BZU Histidine kinase YPC_2993 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPC_2995 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPC_2996 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPC_2997 ENOG4105XPH Ferredoxin YPC_3002 ENOG4105E0U tyrosine-specific transport protein YPC_3003 ENOG4108UII YfaZ family YPC_3004 ENOG4105CH6 catalase YPC_3005 ENOG4105DVT helicase YPC_3007 ENOG4105FDR Membrane YPC_3009 ENOG4105CXN decarboxylase YPC_3010 ENOG4105D5Q Arginine ornithine antiporter YPC_3011 ENOG4105D5Q Arginine ornithine antiporter YPC_3012 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component YPC_3013 ENOG4108IJ8 ABC transporter YPC_3014 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component YPC_3015 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system YPC_3016 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system YPC_3017 ENOG4105KHC sulfurtransferase YPC_3020 ENOG4108IV0 ABC, transporter YPC_3021 ENOG4108JJB ABC transporter YPC_3023 ENOG4105C32 Amino acid ABC transporter (Permease) YPC_3025 ENOG4108W15 Protein of unknown function (DUF1456) YPC_3029 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein YPC_3031 ENOG4105Y3U Transglycosylase-associated protein YPC_3034 ENOG4105N1F Hnh endonuclease YPC_3037 ENOG4105CXG d-lactate dehydrogenase YPC_3038 ENOG41061WM D-Alanyl-D-Alanine YPC_3041 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) YPC_3045 ENOG4105C1J atp-dependent rna helicase YPC_3046 ENOG4105EQR Transposase IS116 IS110 IS902 YPC_3053 ENOG4108WC9 type VI secretion system effector, hcp1 family YPC_3054 ENOG4108RS6 transposase YPC_3058 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) YPC_3060 ENOG4105VPD cellular component movement YPC_3065 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPC_3066 ENOG4105N21 Membrane YPC_3077 ENOG4108MGN ATP-binding component of a transport system YPC_3080 ENOG4108MGN ATP-binding component of a transport system YPC_3083 ENOG4105YYA enhanced serine sensitivity protein SseB YPC_3086 ENOG4105WVQ Fe-S assembly protein IscX YPC_3087 ENOG4108ZIT Ferredoxin, 2FE-2S YPC_3088 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB YPC_3091 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins YPC_3092 ENOG4105C3J Cysteine desulfurase YPC_3097 ENOG4108RS6 transposase YPC_3098 ENOG4105D7X high-affinity nickel-transporter YPC_3099 ENOG41065CD Exported protein YPC_3100 ENOG4108MN2 Stationary phase inducible protein CsiE YPC_3101 ENOG4105D8G Major Facilitator superfamily YPC_3106 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) YPC_3107 ENOG4108M21 YPC_3108 ENOG4108YZA Nitrogen regulatory protein pii YPC_3109 ENOG4105C4K Nad synthetase YPC_3110 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPC_3111 ENOG4108SKK alpha helix protein YPC_3112 ENOG4107WP9 Histidine kinase YPC_3121 ENOG4108Z6B deaminase YPC_3122 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB YPC_3124 ENOG4106G6Q Transcriptional regulator YPC_3125 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding YPC_3126 ENOG4108RS6 transposase YPC_3129 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) YPC_3133 ENOG4105C3F Signal peptidase i YPC_3136 ENOG4105WMJ Positive regulator of sigma E, RseC MucC YPC_3140 ENOG4108IYU L-aspartate oxidase YPC_3142 ENOG4105C1J atp-dependent rna helicase YPC_3156 ENOG4107R7A Allophanate hydrolase subunit 2 YPC_3157 ENOG4105P4J Allophanate hydrolase, subunit 1 YPC_3158 ENOG4107QNR UPF0135 protein YPC_3159 ENOG4107RF4 Phosphodiesterase YPC_3160 ENOG4105CVP deoxyribo-dipyrimidine photolyase YPC_3161 ENOG4107SEY Conserved Protein YPC_3163 ENOG4105XIQ Protein of unknown function (DUF2517) YPC_3167 ENOG4105C08 Histidine kinase YPC_3168 ENOG4105EEX Two component transcriptional regulator (Winged helix family YPC_3172 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 YPC_3177 ENOG4105EZV Transcriptional regulator YPC_3178 ENOG4105VCP PTS System YPC_3179 ENOG4105CK1 PTS System YPC_3180 ENOG4105VZJ PTS System YPC_3182 ENOG41085Q9 Protein CrcB homolog YPC_3183 ENOG41086WQ Protein CrcB homolog YPC_3184 ENOG4107SVH Potassium channel protein YPC_3185 ENOG4105XXV Acid-resistance protein YPC_3190 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) YPC_3199 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPC_3200 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPC_3201 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein YPC_3203 ENOG4105VEQ Cold shock protein YPC_3205 ENOG4108SAJ Protein of unknown function (DUF1198) YPC_3206 ENOG4108WMJ Protein of unknown function (DUF2002) YPC_3211 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPC_3213 ENOG4108IJ7 Glycine betaine YPC_3214 ENOG4108HQS Glycine betaine YPC_3215 ENOG4105GIJ Glycine betaine YPC_3220 ENOG4105DFP Integrase YPC_3225 ENOG4105EV9 Alpha Beta Hydrolase YPC_3227 ENOG4105NNH LexA regulated protein YPC_3229 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) YPC_3230 ENOG41090R7 Ferric uptake YPC_3236 ENOG4108RS6 transposase YPC_3238 ENOG4105CI1 PTS System YPC_3240 ENOG4105CE4 GlcNAc 6-P deacetylase YPC_3241 ENOG4105E2R ROK family YPC_3242 ENOG4105D4U had-superfamily hydrolase, subfamily iia YPC_3244 ENOG4105CAQ asparagine synthetase YPC_3252 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family YPC_3254 ENOG4105C9A Phoh family YPC_3257 ENOG4108JU5 Magnesium and cobalt efflux protein YPC_3258 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) YPC_3259 ENOG4107RP9 extracellular solute-binding protein, family 3 YPC_3260 ENOG4105EAD ABC transporter YPC_3261 ENOG4105DRP amino acid AbC transporter YPC_3262 ENOG4105CDA abc transporter atp-binding protein YPC_3263 ENOG4107PAI alpha helical protein YPC_3267 ENOG4105DJF DNA polymerase III, delta' subunit YPC_3269 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) YPC_3271 ENOG4105CJN penicillin-binding protein YPC_3272 ENOG4105CNI cell division protein FtsW YPC_3273 ENOG4105K6T rare lipoprotein A YPC_3274 ENOG4105DZ1 carboxypeptidase YPC_3278 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) YPC_3280 ENOG4107Z6W Protein CrcB homolog YPC_3284 ENOG4108N8T regulatoR YPC_3289 ENOG4108JJ7 ABC transporter YPC_3290 ENOG4105DH8 myo-inositol catabolism YPC_3292 ENOG4105EDK PfkB domain protein YPC_3293 ENOG4105CK5 oxidoreductase YPC_3294 ENOG4105CNN ABC, transporter YPC_3295 ENOG4105C2J ABC transporter YPC_3296 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPC_3299 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) YPC_3300 ENOG4105C26 Dehydrogenase YPC_3304 ENOG4105DN3 alpha-2-macroglobulin domain protein YPC_3305 ENOG4108RS6 transposase YPC_3307 ENOG4108JQB penicillin-binding protein 1C YPC_3309 ENOG4105HVQ Regulatory factor of maltose metabolism YPC_3314 ENOG4108WC9 type VI secretion system effector, hcp1 family YPC_3320 ENOG4105EZE Cupin 4 family protein YPC_3325 ENOG4107QK4 glycoside hydrolase, family 3 domain protein YPC_3329 ENOG4107SET aldo keto reductase YPC_3330 ENOG4105EQ2 LysR family Transcriptional regulator YPC_3335 ENOG41077RS Phosphatase YPC_3336 ENOG4105E8V Alpha Beta Hydrolase Fold protein YPC_3338 ENOG4108HPI phosphatidate Cytidylyltransferase YPC_3339 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase YPC_3349 ENOG4105WQ3 Rna-binding protein YPC_3350 ENOG4108RS6 transposase YPC_3353 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) YPC_3355 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) YPC_3356 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit YPC_3357 ENOG4105CV6 ABC transporter, permease YPC_3358 ENOG4108I0Y (ABC) transporter YPC_3359 ENOG4108UJV acyl-CoA thioesterase i YPC_3360 ENOG4105E1F short-chain dehydrogenase reductase YPC_3361 ENOG4107QR8 Thioredoxin YPC_3363 ENOG4107QX8 SPFH domain, Band 7 family protein YPC_3364 ENOG4105G5H Membrane YPC_3365 ENOG4108Z6Z Transcriptional regulator YPC_3366 ENOG4105C59 p-type ATPase YPC_3369 ENOG4108Z66 YbaK ebsC protein YPC_3375 ENOG4105EU0 Major facilitator Superfamily YPC_3376 ENOG4105CKD glutathione-regulated potassium-efflux system protein YPC_3377 ENOG4107RE1 Inosine-guanosine kinase YPC_3378 ENOG4108QY5 Ferric enterobactin transport protein YPC_3381 ENOG4105CJT Mannose-1-phosphate guanylyltransferase YPC_3382 ENOG4105C30 Nad-dependent epimerase dehydratase YPC_3385 ENOG4108TJN glycosyl transferase group 1 YPC_3391 ENOG4108SMP Nad-dependent epimerase dehydratase YPC_3392 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase YPC_3393 ENOG4105FAW cDP-glucose 4,6-dehydratase YPC_3394 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase YPC_3395 ENOG4108EX3 reductase YPC_3396 ENOG4108EX3 reductase YPC_3403 ENOG4107QMP dna polymerase iii subunits gamma and tau YPC_3407 ENOG4105WD1 Membrane YPC_3409 ENOG4106428 Protein of unknown function (DUF2496) YPC_3410 ENOG4105EGS Mechanosensitive ion channel YPC_3411 ENOG41090EX DsrE family YPC_3412 ENOG4108IG5 Transcriptional regulator YPC_3413 ENOG4105C1P efflux transporter, rnd family, mfp subunit YPC_3414 ENOG4105BZS acriflavin resistance protein YPC_3416 ENOG4105YK5 50S ribosomal protein L36 YPC_3418 ENOG4108UKR Biofilm formation regulator YbaJ YPC_3419 ENOG4105KF5 hemolysin expression-modulating protein YPC_3421 ENOG41080UX Methyltransferase YPC_3422 ENOG4108MNP Glycoprotein polysaccharide metabolism YPC_3424 ENOG4105C29 acyl-CoA thioesterase YPC_3425 ENOG4105BZU Histidine kinase YPC_3426 ENOG4108YZA Nitrogen regulatory protein pii YPC_3427 ENOG4105BZ1 (ABC) transporter YPC_3428 ENOG4105BZ1 (ABC) transporter YPC_3429 ENOG4108XM1 transcriptional regulator AsnC family YPC_3430 ENOG4105C6T cysteine synthase YPC_3432 ENOG4108NFA extracellular solute-binding protein YPC_3434 ENOG4108TGP Thioesterase superfamily protein YPC_3436 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein YPC_3437 ENOG4105EIN peptidylprolyl cis-trans isomerase YPC_3438 ENOG4105K70 DNA-binding protein YPC_3439 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) YPC_3444 ENOG4105M85 Bola protein YPC_3445 ENOG4105IEY (LipO)protein YPC_3446 ENOG4105EYM Major Facilitator superfamily YPC_3448 ENOG4108NFH Sugar hydrolase YPC_3449 ENOG4105E2S oxidase) subunit II YPC_3450 ENOG4105BZ9 Cytochrome C oxidase, subunit I YPC_3451 ENOG4105CCU oxidase (Subunit III) YPC_3452 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) YPC_3454 ENOG4107RDB Major Facilitator YPC_3456 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) YPC_3457 ENOG4107S0N DJ-1 family YPC_3461 ENOG4105CTB Polyprenyl synthetase YPC_3465 ENOG4108ZAI phosphatidylglycerophosphatase a YPC_3466 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) YPC_3469 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) YPC_3475 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) YPC_3476 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) YPC_3477 ENOG4105VIE preprotein translocase, subunit YajC YPC_3479 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) YPC_3480 ENOG4108ZYK Acyl carrier protein phosphodiesterase YPC_3481 ENOG4105D3R alkyl hydroperoxide reductase YPC_3485 ENOG4105CHR reductase YPC_3486 ENOG4107R28 alpha amylase, catalytic region YPC_3487 ENOG4105C85 amino acid YPC_3488 ENOG4105CWM branched-chain amino acid transport system II carrier protein YPC_3490 ENOG4105BZU Histidine kinase YPC_3491 ENOG4105CK6 Two component transcriptional regulator (Winged helix family YPC_3493 ENOG4107RH8 nuclease SbcCD subunit D YPC_3494 ENOG4105EYH Exonuclease YPC_3495 ENOG4105DKQ ROK family YPC_3503 ENOG4105F2W methyltransferase YPC_3507 ENOG4108RS6 transposase YPC_3520 ENOG4108RS6 transposase YPC_3521 ENOG4108KB2 LysR family Transcriptional regulator YPC_3522 ENOG4105CIN aminoacyl-histidine dipeptidase YPC_3527 ENOG4105CJ2 (LipO)protein YPC_3531 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPC_3532 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPC_3533 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPC_3535 ENOG4105F7V ErfK ybiS ycfS ynhG family protein YPC_3536 ENOG4105E7A Glutamine amidotransferase YPC_3538 ENOG4107QPN acyl-Coa dehydrogenase YPC_3540 ENOG4106YJS accessory processing protein YPC_3549 ENOG4105C5R Aminotransferase YPC_3551 ENOG4105E5Q amino acid AbC transporter YPC_3560 ENOG4105EQ0 Major Facilitator superfamily YPC_3561 ENOG4108UMN azlc family YPC_3562 ENOG4105ZED uncharacterized protein ygaH YPC_3563 ENOG4105NTK Transcriptional repressor Mpra YPC_3564 ENOG4105CW7 secretion protein, HlyD family YPC_3565 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPC_3566 ENOG4105EIB trna rrna methyltransferase YPC_3567 ENOG4105K63 Thioredoxin YPC_3569 ENOG4106IUH DTW domain containing protein YPC_3570 ENOG4105CD5 CoA-binding domain protein YPC_3571 ENOG4105JIM Phosphatidylserine synthase YPC_3572 ENOG4105T42 (LipO)protein YPC_3579 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPC_3580 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase YPC_3581 ENOG4105C34 Pseudouridine synthase YPC_3582 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane YPC_3583 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA YPC_3584 ENOG4108RS6 transposase YPC_3586 ENOG4105CQC Prephenate dehydratase YPC_3590 ENOG4105EHE chorismate mutase- prephenate dehydrogenase YPC_3591 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPC_3592 ENOG4108NEV two component transcriptional regulator, LytTR family YPC_3593 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPC_3594 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPC_3595 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPC_3596 ENOG4108NE3 Salt-induced outer membrane protein YPC_3597 ENOG4108RS6 transposase YPC_3605 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY YPC_3606 ENOG4106KVJ cytochrome C assembly protein YPC_3607 ENOG4108JU6 CBS domain protein YPC_3612 ENOG4105D9M gamma-glutamylcysteine synthetase YPC_3613 ENOG4105W39 Membrane YPC_3614 ENOG4107VXZ Hydrolase YPC_3619 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) YPC_3620 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) YPC_3628 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) YPC_3631 ENOG4105CNN ABC, transporter YPC_3632 ENOG4105C2J ABC transporter YPC_3636 ENOG4108XVM Cytochrome b(562) YPC_3637 ENOG4105CPW cytochrome b561 YPC_3639 ENOG4108NEM leader-binding protein dmsD YPC_3640 ENOG4107KGK dmso reductase anchor subunit YPC_3641 ENOG4105QAX Iron-sulfur YPC_3642 ENOG4107QY8 reductase YPC_3643 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase YPC_3644 ENOG4105E98 transcriptional regulator DeoR family YPC_3647 ENOG4108RS6 transposase YPC_3648 ENOG4105C2J ABC transporter YPC_3649 ENOG4105CNN ABC, transporter YPC_3650 ENOG4105F5R ABC transporter YPC_3651 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase YPC_3652 ENOG4105CMG Carbohydrate kinase YPC_3653 ENOG4107GFK fumarate YPC_3655 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) YPC_3658 ENOG4105D05 Receptor YPC_3660 ENOG4105CA0 peroxidase YPC_3661 ENOG4105E89 ABC transporter YPC_3666 ENOG4105DKT Transcriptional regulator YPC_3668 ENOG4105CMT Dihydroxyacetone kinase YPC_3669 ENOG4105CHR reductase YPC_3670 ENOG4105CPQ Dehydrogenase YPC_3671 ENOG4108YZG isomerase YPC_3673 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) YPC_3674 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPC_3675 ENOG4108K5P (LipO)protein YPC_3680 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) YPC_3682 ENOG4105N0Z inner membrane protein ygbE YPC_3683 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) YPC_3695 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase YPC_3696 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) YPC_3702 ENOG4105DXN mazG family YPC_3704 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) YPC_3705 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) YPC_3707 ENOG4105BZU Histidine kinase YPC_3708 ENOG4105C0H protease YPC_3710 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) YPC_3712 ENOG4105EN6 Membrane YPC_3719 ENOG4105S6R Iron-hydroxamate transporter permease subunit YPC_3720 ENOG4105J76 Periplasmic binding protein YPC_3721 ENOG4105E0A ABC, transporter YPC_3722 ENOG4105BZ4 penicillin-binding protein YPC_3723 ENOG4105CQ7 ATP-dependent helicase YPC_3724 ENOG4107XID 2'-5' rna ligase YPC_3726 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters YPC_3727 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) YPC_3728 ENOG4105DJ0 Poly(A) Polymerase YPC_3729 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YPC_3735 ENOG4105E3A (ABC) transporter YPC_3736 ENOG4105DA5 (ABC) transporter YPC_3737 ENOG41077A9 carbonic anhydrase YPC_3738 ENOG4108UGV hypoxanthine phosphoribosyltransferase YPC_3739 ENOG4105E3B Multicopper oxidase YPC_3740 ENOG4108ZRK uncharacterized protein yacC YPC_3744 ENOG4105RPH Inner membrane protein YddG YPC_3748 ENOG4107QIJ Aconitate hydratase 2 YPC_3750 ENOG4108RS6 transposase YPC_3752 ENOG4107QN2 dihydrolipoyl dehydrogenase YPC_3754 ENOG4107QSN dihydrolipoamide acetyltransferase YPC_3755 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) YPC_3756 ENOG41073TP transcriptional regulator YPC_3757 ENOG4105C85 amino acid YPC_3758 ENOG4106A72 regulatory protein AmpE YPC_3759 ENOG4106A72 regulatory protein AmpE YPC_3760 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPC_3761 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase YPC_3762 ENOG4108ZUW Major pilin subunit YPC_3763 ENOG4107QHF type ii secretion system protein e YPC_3764 ENOG4105D7Q type ii secretion system YPC_3766 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) YPC_3772 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) YPC_3779 ENOG4105MYG DNA polymerase iii, chi subunit YPC_3780 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) YPC_3781 ENOG4108MJ3 acetyltransferase YPC_3782 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) YPC_3783 ENOG4105DBV ornithine carbamoyltransferase YPC_3784 ENOG4105XEP YhcH YjgK YiaL family protein YPC_3787 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPC_3788 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPC_3789 ENOG4105C3U ABC transporter YPC_3791 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase YPC_3792 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) YPC_3795 ENOG4107RJJ Transcriptional regulator YPC_3796 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG YPC_3797 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH YPC_3798 ENOG4105EKV Phosphonate metabolism protein YPC_3799 ENOG4105FT8 Phosphonate metabolism YPC_3800 ENOG4105ENV phosphonate C-P lyase system protein PhnK YPC_3801 ENOG4105HRV phosphonate c-p lyase system protein phnl YPC_3802 ENOG4105FD8 phosphonate metabolism protein PhnM YPC_3803 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) YPC_3804 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein YPC_3805 ENOG4105K4T epimerase YPC_3809 ENOG4105DRS transport system, permease YPC_3810 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component YPC_3815 ENOG4108YYD acetyltransferase YPC_3816 ENOG4105XPQ lipid carrier protein YPC_3818 ENOG4105CFP Peptidase U32 YPC_3819 ENOG4106RZ4 Peptidase U32 YPC_3820 ENOG4105ENJ RND efflux system, outer membrane lipoprotein YPC_3821 ENOG4105BZS acriflavin resistance protein YPC_3824 ENOG4105DEN Luciferase family YPC_3825 ENOG4105DEN Luciferase family YPC_3830 ENOG4105C1J atp-dependent rna helicase YPC_3833 ENOG4105DQ6 Transposase YPC_3837 ENOG4108M3R transcriptional activator CadC YPC_3841 ENOG4105E1Q flagellar hook-associated protein YPC_3843 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) YPC_3844 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) YPC_3845 ENOG4105CGA flagellar basal-body rod protein FlgG YPC_3846 ENOG4108KPB Flagellar basal-body rod protein FlgF YPC_3847 ENOG4105BZE flagellar hook protein, FlgE YPC_3848 ENOG4105W00 Flagellar hook capping protein YPC_3849 ENOG4108ZC9 flagellar basal-body rod protein flgc YPC_3850 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) YPC_3851 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA YPC_3855 ENOG4108JIR Flagellum-specific ATP synthase YPC_3858 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) YPC_3860 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPC_3862 ENOG4105DD5 Flagellar motor switch protein YPC_3863 ENOG4105CN7 Flagellar biosynthetic protein FliP YPC_3864 ENOG4105VS8 Flagellar biosynthetic protein fliq YPC_3865 ENOG4105D19 Role in flagellar biosynthesis (By similarity) YPC_3866 ENOG4105D00 flagellar biosynthetic protein flhB YPC_3873 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein YPC_3875 ENOG4106P2F Pfam:Pili_assembly_C YPC_3876 ENOG4106PG1 outer membrane usher protein YPC_3891 ENOG4108ZZF transport protein (ExbD) YPC_3892 ENOG4105CWK Biopolymer transport protein, ExbB YPC_3893 ENOG4105C28 cystathionine YPC_3894 ENOG4108K81 inner membrane protein YghB YPC_3895 ENOG4105CF7 AraC family transcriptional regulator YPC_3896 ENOG4108I6A alcohol dehydrogenase YPC_3898 ENOG4105CV8 reductase YPC_3901 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) YPC_3902 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase YPC_3903 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPC_3904 ENOG4105NF4 modulator of drug activity YPC_3905 ENOG4105CR8 Transcriptional regulator YPC_3906 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPC_3907 ENOG4105IPS esterase YPC_3908 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) YPC_3910 ENOG4108SX3 cytoplasmic protein YPC_3911 ENOG41087AY ADP-Ribose pyrophosphatase YPC_3912 ENOG4105DFG type I secretion outer membrane protein YPC_3915 ENOG4106032 Glutathionylspermidine synthase YPC_3916 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b YPC_3919 ENOG4105W0Z cytoplasmic protein YPC_3921 ENOG4105DVH amino acid YPC_3925 ENOG4105I7R Adenylate cyclase YPC_3926 ENOG4106MWK domain protein YPC_3929 ENOG4107ZVW dihydroneopterin aldolase YPC_3933 ENOG4105VCC 30S ribosomal protein S21 YPC_3934 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) YPC_3935 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPC_3952 ENOG4105KME endoribonuclease L-psp YPC_3957 ENOG4105CHM Aminotransferase YPC_3960 ENOG4105J12 Multidrug resistance protein mdtN YPC_3961 ENOG4108MI0 Resistance protein YPC_3963 ENOG4107QK4 glycoside hydrolase, family 3 domain protein YPC_3965 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component YPC_3967 ENOG4108IJG ABC transporter substrate-binding protein YPC_3968 ENOG4107KJX Transcriptional regulator YPC_3969 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 YPC_3974 ENOG4105CKT filamentous hemagglutinin YPC_3975 ENOG4105CKT filamentous hemagglutinin YPC_3978 ENOG4105CKT filamentous hemagglutinin YPC_3979 ENOG4105CKT filamentous hemagglutinin YPC_3980 ENOG4105CKT filamentous hemagglutinin YPC_3981 ENOG4105CKT filamentous hemagglutinin YPC_3982 ENOG4105D5K Hemolysin activator protein YPC_3983 ENOG4108M24 von Willebrand factor, type A YPC_3986 ENOG4108M24 von Willebrand factor, type A YPC_3989 ENOG4108YK4 Acid-resistance membrane protein YPC_3991 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPC_3994 ENOG4108VKG metal-dependent hydrolase YPC_3995 ENOG4105EE0 oxidoreductase YPC_3998 ENOG4108RS6 transposase YPC_4005 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) YPC_4006 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) YPC_4008 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) YPC_4009 ENOG4105D3G Pseudouridine synthase YPC_4018 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPC_4019 ENOG4105CS6 Rhs element vgr protein YPC_4032 ENOG4105CQ2 DNA polymerase YPC_4033 ENOG4108KF1 Membrane YPC_4035 ENOG4106SMU thiamine transporter membrane protein YPC_4036 ENOG4105DP9 ABC transporter YPC_4040 ENOG4105S8Q sugar efflux transporter YPC_4044 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) YPC_4046 ENOG4108RS6 transposase YPC_4049 ENOG41064T2 transcriptional regulator, lysR family YPC_4050 ENOG4108IQE Amp-dependent synthetase and ligase YPC_4051 ENOG4105C7K acetolactate synthase YPC_4052 ENOG4108ZP8 Acetolactate synthase small subunit YPC_4054 ENOG4108RS6 transposase YPC_4055 ENOG4107B7Y DNA-binding transcriptional regulator FruR YPC_4056 ENOG4108RNS Exports L-alanine (By similarity) YPC_4060 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) YPC_4061 ENOG4105CJN penicillin-binding protein YPC_4062 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) YPC_4063 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) YPC_4066 ENOG4105CNI cell division protein FtsW YPC_4070 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) YPC_4071 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) YPC_4072 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) YPC_4078 ENOG4105M6F mutator MutT protein YPC_4082 ENOG4105CHF Glutathione S-transferase YPC_4083 ENOG4108VBZ doxx family YPC_4085 ENOG41090KG Inner membrane protein YqjE YPC_4086 ENOG4105NE1 Conserved Protein YPC_4090 ENOG4106W5V Membrane YPC_4093 ENOG4105DPW Major facilitator superfamily MFS_1 YPC_4095 ENOG4107QZW Altronate oxidoreductase YPC_4096 ENOG4105CTX dehydratase YPC_4097 ENOG4105P66 Membrane YPC_4098 ENOG4108RS6 transposase YPC_4100 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) YPC_4102 ENOG4105DWK Membrane YPC_4103 ENOG4105N14 lysine exporter protein LysE YggA YPC_4104 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain YPC_4105 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain YPC_4107 ENOG4108RS6 transposase YPC_4113 ENOG4105DTN riboflavin biosynthesis protein ribF YPC_4115 ENOG41063Z6 transcriptional regulator, lysR family YPC_4119 ENOG4106HK8 GPR1 FUN34 yaaH family protein YPC_4122 ENOG4108RIR Molybdenum cofactor biosynthesis protein YPC_4132 ENOG41065U4 response regulator YPC_4133 ENOG4108RH0 Crea protein YPC_4134 ENOG4105UEI Transcriptional Regulator AraC Family YPC_4137 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) YPC_4138 ENOG4107SC1 transglycosylase YPC_4141 ENOG4108KHX Diguanylate cyclase YPC_4142 ENOG41090EK ompa motb domain protein YPC_4143 ENOG4105C5H ABC transporter YPC_4144 ENOG4105C5H ABC transporter YPC_4146 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase YPC_4147 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) YPC_4148 ENOG4105EAC phosphoserine phosphatase YPC_4150 ENOG41062Z9 Membrane YPC_4155 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPC_4157 ENOG4105D9N nucleoside YPC_4161 ENOG4108NRW Phospholipase, patatin family YPC_4162 ENOG4108NRW Phospholipase, patatin family YPC_4164 ENOG4105K3G Periplasmic Protein YPC_4166 ENOG4105KEG ribosomal-protein-alanine acetyltransferase YPC_4167 ENOG4108WPU DNA polymerase III subunit psi YPC_4172 ENOG4105YBH Protein of unknown function (DUF1435) YPC_4173 ENOG4105BZU Histidine kinase YPC_4179 ENOG4105BZS acriflavin resistance protein YPC_4180 ENOG410624X efflux transporter, rnd family, mfp subunit YPC_4184 ENOG4105DKP glycosyl transferase, family 9 YPC_4187 ENOG4105DKT Transcriptional regulator YPC_4188 ENOG4105DKT Transcriptional regulator YPC_4198 ENOG4105RI1 glycoprotein receptor YPC_4199 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) YPC_4200 ENOG4105DM4 PTS System YPC_4201 ENOG4108YRF PTS System YPC_4202 ENOG4108XCZ PTS System YPC_4203 ENOG4106R3P AraC family transcriptional regulator YPC_4205 ENOG4108M3P Membrane YPC_4216 ENOG4105CMM transposase YPC_4219 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 YPC_4223 ENOG4107S2Z UPF0761 membrane protein YPC_4224 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 YPC_4226 ENOG4105C5F glutamine synthetase YPC_4227 ENOG4105CUX Signal transduction histidine kinase YPC_4228 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPC_4229 ENOG4105D4P Coproporphyrinogen iii oxidase YPC_4234 ENOG4108RS6 transposase YPC_4238 ENOG4105C2M dna polymerase I YPC_4239 ENOG4108Z33 Thiol disulfide Interchange Protein YPC_4240 ENOG4105E27 serine threonine protein kinase YPC_4241 ENOG4105PC1 Conserved Protein YPC_4243 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b YPC_4253 ENOG4105CHF Glutathione S-transferase YPC_4254 ENOG4105CWB LysR family transcriptional Regulator YPC_4255 ENOG4108CNN domain protein YPC_4258 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) YPC_4262 ENOG4105W4M Transport-associated protein YPC_4264 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain YPC_4267 ENOG4105BZU Histidine kinase YPC_4269 ENOG4105N5T Radical SAM Protein YPC_4270 ENOG4105CBC glutamate synthase YPC_4271 ENOG4105BZ8 glutamate synthase YPC_4273 ENOG4105KB2 stringent starvation protein b YPC_4274 ENOG4107MKT Stringent starvation protein a YPC_4277 ENOG4105D6Z AFG1 family ATPase YPC_4278 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III YPC_4279 ENOG4105C0H protease YPC_4280 ENOG4108RS6 transposase YPC_4282 ENOG4105C0H protease YPC_4284 ENOG4105VFK BolA family YPC_4285 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane YPC_4286 ENOG4105E3I toluene tolerance YPC_4287 ENOG4107PE3 Mammalian cell entry related domain protein YPC_4288 ENOG4105CY3 ABC transporter, permease YPC_4289 ENOG4105DHJ ABC, transporter YPC_4290 ENOG4105FEU K -dependent Na -Ca exchanger YPC_4291 ENOG4105C2X Arabinose 5-phosphate isomerase YPC_4292 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase YPC_4293 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) YPC_4294 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA YPC_4295 ENOG4108IUZ ABC transporter YPC_4296 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPC_4297 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA YPC_4298 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA YPC_4299 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN YPC_4301 ENOG41080Z8 PHOSPHOCARRIER protein YPC_4304 ENOG4105KME endoribonuclease L-psp YPC_4306 ENOG4105D4X repressor YPC_4307 ENOG4105C5Y PTS System YPC_4308 ENOG4105CG3 alpha amylase, catalytic region YPC_4309 ENOG4105NXH GreA GreB family elongation factor YPC_4311 ENOG4108XVM Cytochrome b(562) YPC_4313 ENOG4105CMS peptidase U62, modulator of DNA gyrase YPC_4315 ENOG4105UNR (Barnase) inhibitor YPC_4323 ENOG4105CR8 Transcriptional regulator YPC_4335 ENOG4105D1U peptidase U62 modulator of DNA gyrase YPC_4337 ENOG4105QD6 exported protein YPC_4338 ENOG4105C03 ribonuclease YPC_4340 ENOG4105VQ7 Rod shape-determining protein MreD YPC_4341 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) YPC_4342 ENOG4105DFF Rod shape-determining protein mreb YPC_4343 ENOG41062P1 Diguanylate cyclase phosphodiesterase YPC_4344 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family YPC_4345 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) YPC_4348 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein YPC_4349 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase YPC_4352 ENOG4105RG0 Membrane YPC_4353 ENOG4108IA2 Sodium pantothenate symporter YPC_4356 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) YPC_4357 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) YPC_4361 ENOG4105CSH Transporter YPC_4362 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase YPC_4365 ENOG4108XTF Outer Membrane Lipoprotein YPC_4367 ENOG4105VEQ Cold shock protein YPC_4368 ENOG4105VEQ Cold shock protein YPC_4373 ENOG4105CYM Glutathione S-transferase YPC_4374 ENOG4105C2X Arabinose 5-phosphate isomerase YPC_4375 ENOG4105EF1 ribulokinase YPC_4377 ENOG4105CNN ABC, transporter YPC_4378 ENOG4105C2J ABC transporter YPC_4380 ENOG4105D1S lipid A biosynthesis YPC_4382 ENOG4105EEQ Na H antiporter YPC_4383 ENOG4105C7N Xanthine uracil vitamin C permease YPC_4388 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component YPC_4390 ENOG4105GVF (ABC) transporter YPC_4393 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPC_4395 ENOG4108RVA ribokinase YPC_4396 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) YPC_4398 ENOG4105W4W Transcriptional regulator YPC_4399 ENOG4107TYG Oxidoreductase domain-containing protein YPC_4402 ENOG4105CNA YD repeat protein YPC_4404 ENOG4105CS6 Rhs element vgr protein YPC_4415 ENOG4105CS6 Rhs element vgr protein YPC_4422 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPC_4431 ENOG4105DQ6 Transposase YPC_4435 ENOG4105C6V Glycerol-3-phosphate dehydrogenase YPC_4436 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) YPC_4442 ENOG4108HRK Histidine kinase YPC_4443 ENOG4105TNG K13735 adhesin invasin YPC_4444 ENOG4105TNG K13735 adhesin invasin YPC_4450 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) YPC_4451 ENOG41076UM multiple antibiotic resistance (MarC)-related protein YPC_4455 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family YPC_4457 ENOG4105C6Z Gluconate YPC_4459 ENOG4105DIQ Transcriptional regulator YPC_4460 ENOG4105C2I pirin domain protein YPC_4463 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPC_4465 ENOG4105D2N Aldolase YPC_4467 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPC_4468 ENOG4105CNN ABC, transporter YPC_4471 ENOG4105CBX hi0933 family YPC_4472 ENOG4105CJ3 phosphate transporter YPC_4476 ENOG4108M6U Universal stress protein A YPC_4480 ENOG4105DGW oligopeptidase A YPC_4482 ENOG4105D6S protein involved in catabolism of external DNA YPC_4483 ENOG4105DC8 reductase YPC_4484 ENOG4107VHA regulatoR YPC_4487 ENOG4107QQ0 gntp family YPC_4488 ENOG4105BZW Glycerate kinase YPC_4493 ENOG4107H3J ribonuclease YPC_4494 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) YPC_4497 ENOG4105CMB EAL domain-containing protein YPC_4498 ENOG4105VSH 4-oxalocrotonate tautomerase YPC_4499 ENOG4107SS6 2-dehydro-3-deoxygluconokinase YPC_4500 ENOG4105CS0 peptidase YPC_4504 ENOG4108PU9 oligogalacturonate-specific porin YPC_4505 ENOG4105BZU Histidine kinase YPC_4507 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) YPC_4508 ENOG4108JQ7 (ABC) transporter YPC_4509 ENOG4105C3U ABC transporter YPC_4510 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPC_4511 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPC_4512 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPC_4513 ENOG4105DEF Extracellular solute-binding protein, family 5 YPC_4515 ENOG4105D5K Hemolysin activator protein YPC_4517 ENOG4108RS6 transposase YPC_4519 ENOG4105CXY transporter YPC_4522 ENOG4108KX4 response regulator YPC_4523 ENOG4105DIJ Phosphoethanolamine transferase YPC_4525 ENOG4105C85 amino acid YPC_4526 ENOG4105C84 Histidine ammonia-lyase YPC_4528 ENOG4105C6T cysteine synthase YPC_4535 ENOG4108IPW abc transporter atp-binding protein YPC_4543 ENOG4105ZTC transcriptional activator, Ogr delta YPC_4545 ENOG4105DFP Integrase YPC_4547 ENOG4105T16 Transcriptional regulator (AraC family) YPC_4548 ENOG4107RNG ABC transporter YPC_4550 ENOG4105DFW ABC transporter YPC_4552 ENOG4105CMG Carbohydrate kinase YPC_4554 ENOG4108TTM chaperone YPC_4558 ENOG4106EAR Fimbrial protein YPC_4560 ENOG4105MEV Acyl-transferase YPC_4563 ENOG4105DQ6 Transposase YPC_4568 ENOG4105D13 transposase YPC_4573 ENOG4108MG3 formate dehydrogenase YPC_4574 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein YPC_4579 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) YPC_4580 ENOG4105C8Q Methyl-accepting chemotaxis YPC_4584 ENOG4108YYI Protein of unknown function (DUF2810) YPC_4586 ENOG4105E61 Mannitol repressor protein YPC_4588 ENOG4105CTS PTS system mannitol-specific YPC_4590 ENOG4106JH6 (LipO)protein YPC_4594 ENOG4108R3E Dna-3-methyladenine glycosylase i YPC_4597 ENOG4108ZG0 Ompa motb domain protein YPC_4600 ENOG4107T9C Alpha amylase catalytic region YPC_4602 ENOG4105JKW Valine--pyruvate aminotransferase YPC_4607 ENOG4105R2A (LipO)protein YPC_4608 ENOG4105D99 atp gtp-binding protein YPC_4609 ENOG4105D99 atp gtp-binding protein YPC_4610 ENOG4105C7B Threonine dehydratase YPC_4613 ENOG4105DQ6 Transposase YPC_4614 ENOG410667J hydrolase YPC_4615 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPC_4616 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) YPC_4617 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) YPC_4620 ENOG4105VG0 50S ribosomal protein l34 YPC_4623 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins YPC_4629 ENOG4105C7N Xanthine uracil vitamin C permease YPC_4631 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 YPC_4632 ENOG4105DRP amino acid AbC transporter YPC_4633 ENOG4105EAD ABC transporter YPC_4634 ENOG4106PMH Extracellular solute-binding protein family 3 YPC_4638 ENOG4105E2Z phosphate ABC transporter (Permease YPC_4639 ENOG4105C8U phosphate abc transporter YPC_4640 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) YPC_4642 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) YPC_4652 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) YPC_4654 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YPC_4735 ENOG4105E5H Transposase YPC_4736 ENOG4105CMM transposase YPC_4744 ENOG4106CQM replication YPC_4746 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) YPC_4755 ENOG4105D13 transposase YPC_4756 ENOG4108C33 Resolvase YPC_4760 ENOG4105CMM transposase YPC_4766 ENOG4105UZW Tail fiber assembly protein YPC_4767 ENOG4108X9F tail fiber protein YPC_4767 ENOG4108X9F tail fiber protein YPC_4774 ENOG4108NYK Tape measure protein YPC_4794 ENOG4105FA0 parb-like partition protein YPC_4795 ENOG4105FA0 parb-like partition protein YPC_4796 ENOG4105CB5 ATP-dependent DNA helicase recG YPC_4812 ENOG4105D2X ABC transporter substrate-binding protein YPC_4815 ENOG4106JVB Replication Protein YPC_4824 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) YPC_4826 ENOG4105C2M dna polymerase I YPC_4831 ENOG4106J5W DNA polymerase III (alpha subunit) YPC_4839 ENOG4108D1K outer membrane usher protein YPC_4840 ENOG4108UIF Chaperone YPC_4841 ENOG4106PHM regulatory protein YPC_4849 ENOG4105FEQ ParB domain protein nuclease YPC_4853 ENOG41073YN Protein of unknown function (DUF1380) YPC_4860 ENOG4106RMF ParB family YPC_4870 ENOG4105EKQ RNA-directed DNA polymerase YPC_4874 ENOG4105EQR Transposase IS116 IS110 IS902 YPC_4889 ENOG4105XUP Phage derived protein Gp49-like (DUF891)